LOCUS       DAVLUM010000001        63786 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLUM010000001 DAVLUM010000000
VERSION     DAVLUM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.001"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            109..804
                     /locus_tag="VYN42_000001"
     CDS             109..804
                     /locus_tag="VYN42_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1461159.1"
                     /translation="MKEKGFWEGAQAAMPTALGYVSIGLACGIIGAPYVTPVEMGLMS
                     LFVYAGSAQFAMLALIAVKAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWQNIGM
                     SSILTDETYGVLMGELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIF
                     GLDFALVGMFIGIFASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFAT
                     LLGCTMGVVLDGQ"
     gene            794..1117
                     /locus_tag="VYN42_000002"
     CDS             794..1117
                     /locus_tag="VYN42_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1461160.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGNVGSLPQIKWLDFLAIFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            1221..2051
                     /locus_tag="VYN42_000003"
     CDS             1221..2051
                     /locus_tag="VYN42_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1461161.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2205..3059
                     /locus_tag="VYN42_000004"
     CDS             2205..3059
                     /locus_tag="VYN42_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1461162.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3159..4532
                     /locus_tag="VYN42_000005"
     CDS             3159..4532
                     /locus_tag="VYN42_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1461163.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLHGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVETAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4525..5586
                     /locus_tag="VYN42_000006"
     CDS             4525..5586
                     /locus_tag="VYN42_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1461164.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5588..6280
                     /locus_tag="VYN42_000007"
     CDS             5588..6280
                     /locus_tag="VYN42_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461165.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6310..6879)
                     /locus_tag="VYN42_000008"
     CDS             complement(6310..6879)
                     /locus_tag="VYN42_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1461166.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7014..7628
                     /locus_tag="VYN42_000009"
     CDS             7014..7628
                     /locus_tag="VYN42_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1461167.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLVGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7630..9276
                     /locus_tag="VYN42_000010"
     CDS             7630..9276
                     /locus_tag="VYN42_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1461168.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRK
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9288..10574
                     /locus_tag="VYN42_000011"
     CDS             9288..10574
                     /locus_tag="VYN42_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1461169.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10626..11159
                     /locus_tag="VYN42_000012"
     CDS             10626..11159
                     /locus_tag="VYN42_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461170.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11237..11707
                     /gene="nrdI"
                     /locus_tag="VYN42_000013"
     CDS             11237..11707
                     /gene="nrdI"
                     /locus_tag="VYN42_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1461171.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12000..13262)
                     /locus_tag="VYN42_000014"
     CDS             complement(12000..13262)
                     /locus_tag="VYN42_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1461172.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13572..14030)
                     /locus_tag="VYN42_000015"
     CDS             complement(13572..14030)
                     /locus_tag="VYN42_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1461173.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14027..14467)
                     /locus_tag="VYN42_000016"
     CDS             complement(14027..14467)
                     /locus_tag="VYN42_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1461174.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14823..16772
                     /gene="mutL"
                     /locus_tag="VYN42_000017"
     CDS             14823..16772
                     /gene="mutL"
                     /locus_tag="VYN42_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1461175.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17097..17564)
                     /locus_tag="VYN42_000018"
     CDS             complement(17097..17564)
                     /locus_tag="VYN42_000018"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1461176.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17565..18770)
                     /locus_tag="VYN42_000019"
     CDS             complement(17565..18770)
                     /locus_tag="VYN42_000019"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1461177.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18790..19425)
                     /gene="ribE"
                     /locus_tag="VYN42_000020"
     CDS             complement(18790..19425)
                     /gene="ribE"
                     /locus_tag="VYN42_000020"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1461178.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19410..20510)
                     /gene="ribD"
                     /locus_tag="VYN42_000021"
     CDS             complement(19410..20510)
                     /gene="ribD"
                     /locus_tag="VYN42_000021"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1461179.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20644..20758)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20915..21508
                     /gene="ruvA"
                     /locus_tag="VYN42_000022"
     CDS             20915..21508
                     /gene="ruvA"
                     /locus_tag="VYN42_000022"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1461180.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21518..22081
                     /locus_tag="VYN42_000023"
     CDS             21518..22081
                     /locus_tag="VYN42_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1461181.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22078..22755
                     /locus_tag="VYN42_000024"
     CDS             22078..22755
                     /locus_tag="VYN42_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1461182.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIIMV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22909..23940)
                     /locus_tag="VYN42_000025"
     CDS             complement(22909..23940)
                     /locus_tag="VYN42_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1461183.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIIPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24195..24878)
                     /locus_tag="VYN42_000026"
     CDS             complement(24195..24878)
                     /locus_tag="VYN42_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1461184.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24890..25834)
                     /locus_tag="VYN42_000027"
     CDS             complement(24890..25834)
                     /locus_tag="VYN42_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1461185.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25966..28797
                     /gene="uvrA"
                     /locus_tag="VYN42_000028"
     CDS             25966..28797
                     /gene="uvrA"
                     /locus_tag="VYN42_000028"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1461186.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28790..29851
                     /locus_tag="VYN42_000029"
     CDS             28790..29851
                     /locus_tag="VYN42_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1461187.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            29983..30381
                     /gene="spx"
                     /locus_tag="VYN42_000030"
     CDS             29983..30381
                     /gene="spx"
                     /locus_tag="VYN42_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1461188.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30447..31016
                     /locus_tag="VYN42_000031"
     CDS             30447..31016
                     /locus_tag="VYN42_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1461189.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31103..31369
                     /locus_tag="VYN42_000032"
     CDS             31103..31369
                     /locus_tag="VYN42_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1461190.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31373..31792
                     /gene="ruvX"
                     /locus_tag="VYN42_000033"
     CDS             31373..31792
                     /gene="ruvX"
                     /locus_tag="VYN42_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1461191.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31808..32113
                     /locus_tag="VYN42_000034"
     CDS             31808..32113
                     /locus_tag="VYN42_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1461192.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32372..33622
                     /locus_tag="VYN42_000035"
     CDS             32372..33622
                     /locus_tag="VYN42_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1461193.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLHPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTDFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33619..34176
                     /locus_tag="VYN42_000036"
     CDS             33619..34176
                     /locus_tag="VYN42_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1461194.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34322..35854
                     /gene="cls"
                     /locus_tag="VYN42_000037"
     CDS             34322..35854
                     /gene="cls"
                     /locus_tag="VYN42_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1461195.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            35932..36075
                     /locus_tag="VYN42_000038"
     CDS             35932..36075
                     /locus_tag="VYN42_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461196.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            36112..37650
                     /locus_tag="VYN42_000039"
     CDS             36112..37650
                     /locus_tag="VYN42_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1461197.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37770..39977
                     /gene="nrdD"
                     /locus_tag="VYN42_000040"
     CDS             37770..39977
                     /gene="nrdD"
                     /locus_tag="VYN42_000040"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1461198.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLVDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            39989..40129
                     /locus_tag="VYN42_000041"
     CDS             39989..40129
                     /locus_tag="VYN42_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461199.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40173..40679
                     /locus_tag="VYN42_000042"
     CDS             40173..40679
                     /locus_tag="VYN42_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461200.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            40672..41262
                     /gene="nrdG"
                     /locus_tag="VYN42_000043"
     CDS             40672..41262
                     /gene="nrdG"
                     /locus_tag="VYN42_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1461201.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41259..41876
                     /locus_tag="VYN42_000044"
     CDS             41259..41876
                     /locus_tag="VYN42_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1461202.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTSAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTAGLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFRPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42142..42450
                     /gene="rpsJ"
                     /locus_tag="VYN42_000045"
     CDS             42142..42450
                     /gene="rpsJ"
                     /locus_tag="VYN42_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1461203.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42667..43293
                     /gene="rplC"
                     /locus_tag="VYN42_000046"
     CDS             42667..43293
                     /gene="rplC"
                     /locus_tag="VYN42_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1461204.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43318..43941
                     /gene="rplD"
                     /locus_tag="VYN42_000047"
     CDS             43318..43941
                     /gene="rplD"
                     /locus_tag="VYN42_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1461205.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            43941..44237
                     /locus_tag="VYN42_000048"
     CDS             43941..44237
                     /locus_tag="VYN42_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1461206.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44255..45088
                     /gene="rplB"
                     /locus_tag="VYN42_000049"
     CDS             44255..45088
                     /gene="rplB"
                     /locus_tag="VYN42_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1461207.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45192..45473
                     /gene="rpsS"
                     /locus_tag="VYN42_000050"
     CDS             45192..45473
                     /gene="rpsS"
                     /locus_tag="VYN42_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1461208.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45485..45829
                     /gene="rplV"
                     /locus_tag="VYN42_000051"
     CDS             45485..45829
                     /gene="rplV"
                     /locus_tag="VYN42_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1461209.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45842..46495
                     /gene="rpsC"
                     /locus_tag="VYN42_000052"
     CDS             45842..46495
                     /gene="rpsC"
                     /locus_tag="VYN42_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1461210.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46499..46912
                     /gene="rplP"
                     /locus_tag="VYN42_000053"
     CDS             46499..46912
                     /gene="rplP"
                     /locus_tag="VYN42_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1461211.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46922..47128
                     /locus_tag="VYN42_000054"
     CDS             46922..47128
                     /locus_tag="VYN42_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1461212.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47153..47413
                     /gene="rpsQ"
                     /locus_tag="VYN42_000055"
     CDS             47153..47413
                     /gene="rpsQ"
                     /locus_tag="VYN42_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1461213.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47439..47807
                     /gene="rplN"
                     /locus_tag="VYN42_000056"
     CDS             47439..47807
                     /gene="rplN"
                     /locus_tag="VYN42_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1461214.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47885..48190
                     /gene="rplX"
                     /locus_tag="VYN42_000057"
     CDS             47885..48190
                     /gene="rplX"
                     /locus_tag="VYN42_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1461215.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48214..48756
                     /gene="rplE"
                     /locus_tag="VYN42_000058"
     CDS             48214..48756
                     /gene="rplE"
                     /locus_tag="VYN42_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1461216.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48774..49043
                     /gene="rpsN"
                     /locus_tag="VYN42_000059"
     CDS             48774..49043
                     /gene="rpsN"
                     /locus_tag="VYN42_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1461217.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49328..49726
                     /gene="rpsH"
                     /locus_tag="VYN42_000060"
     CDS             49328..49726
                     /gene="rpsH"
                     /locus_tag="VYN42_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1461218.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49918..50454
                     /gene="rplF"
                     /locus_tag="VYN42_000061"
     CDS             49918..50454
                     /gene="rplF"
                     /locus_tag="VYN42_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1461219.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50538..50894
                     /gene="rplR"
                     /locus_tag="VYN42_000062"
     CDS             50538..50894
                     /gene="rplR"
                     /locus_tag="VYN42_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1461220.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50912..51406
                     /gene="rpsE"
                     /locus_tag="VYN42_000063"
     CDS             50912..51406
                     /gene="rpsE"
                     /locus_tag="VYN42_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1461221.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51378..51602
                     /gene="rpmD"
                     /locus_tag="VYN42_000064"
     CDS             51378..51602
                     /gene="rpmD"
                     /locus_tag="VYN42_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1461222.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            51747..52187
                     /gene="rplO"
                     /locus_tag="VYN42_000065"
     CDS             51747..52187
                     /gene="rplO"
                     /locus_tag="VYN42_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1461223.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52200..53510
                     /gene="secY"
                     /locus_tag="VYN42_000066"
     CDS             52200..53510
                     /gene="secY"
                     /locus_tag="VYN42_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1461224.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53661..54299
                     /locus_tag="VYN42_000067"
     CDS             53661..54299
                     /locus_tag="VYN42_000067"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1461225.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54416..54634
                     /gene="infA"
                     /locus_tag="VYN42_000068"
     CDS             54416..54634
                     /gene="infA"
                     /locus_tag="VYN42_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1461226.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54659..54775
                     /gene="rpmJ"
                     /locus_tag="VYN42_000069"
     CDS             54659..54775
                     /gene="rpmJ"
                     /locus_tag="VYN42_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1461227.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54793..55158
                     /gene="rpsM"
                     /locus_tag="VYN42_000070"
     CDS             54793..55158
                     /gene="rpsM"
                     /locus_tag="VYN42_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1461228.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55176..55559
                     /gene="rpsK"
                     /locus_tag="VYN42_000071"
     CDS             55176..55559
                     /gene="rpsK"
                     /locus_tag="VYN42_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1461229.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55602..56537
                     /locus_tag="VYN42_000072"
     CDS             55602..56537
                     /locus_tag="VYN42_000072"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1461230.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56549..56935
                     /gene="rplQ"
                     /locus_tag="VYN42_000073"
     CDS             56549..56935
                     /gene="rplQ"
                     /locus_tag="VYN42_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1461231.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57200..57466
                     /locus_tag="VYN42_000074"
     CDS             57200..57466
                     /locus_tag="VYN42_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1461232.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAIVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57476..58813
                     /locus_tag="VYN42_000075"
     CDS             57476..58813
                     /locus_tag="VYN42_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1461233.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59057..59749
                     /locus_tag="VYN42_000076"
     CDS             59057..59749
                     /locus_tag="VYN42_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1461234.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59852..61498)
                     /locus_tag="VYN42_000077"
                     /pseudo
     CDS             complement(59852..61498)
                     /locus_tag="VYN42_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(61488..62580)
                     /locus_tag="VYN42_000078"
                     /pseudo
     CDS             complement(61488..62580)
                     /locus_tag="VYN42_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62593..63714)
                     /locus_tag="VYN42_000079"
                     /pseudo
     CDS             complement(62593..63714)
                     /locus_tag="VYN42_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        19098 a        12018 c        14122 g        18548 t
ORIGIN      
        1 tcagttctat ctgcaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt
       61 tgctctttga ttttcattga gtattattaa ggcaatatga ggagaaagat gaaagaaaaa
      121 ggattttggg agggggcgca ggcagccatg ccaacggccc ttggttatgt cagtatcgga
      181 ctggcctgtg ggattatcgg tgcgccctat gtgacacctg tagagatggg cttgatgagc
      241 ctctttgttt atgctgggag tgcccagttt gccatgctgg cactgattgc ggttaaagcg
      301 cctgtggcag ctattgctat gacggtcttt ttgattaatt tgcgtctctt tttgctgagc
      361 ttacatgcgt cgacctattt ccgtcatacc agtctctggc aaaatatcgg tatgtctagt
      421 atcttgacag atgagaccta tggcgttttg atgggcgagt tagcccatac agacaaggtc
      481 aatcctatgt ggatgcacgg aaacaacctc aatagctatg tggcttggtt tgtggggaca
      541 gtagtcggaa cggctctggg tggcctgcta ccaaatccag agatctttgg tttagatttt
      601 gccctagttg ggatgtttat cggcattttt gcttcgcaat tccagattat gcaaagacgg
      661 attcccgtcc gaaatctact gattatccta gcagttgttg cggtgtcctt ctttttactc
      721 ttaacagtgg tgtctcagtc gctagctgtt ctgtttgcga ccttgctagg ttgtacaatg
      781 ggggtggttt tagatggtca gtaagtatct tttattagca gttattttct ctggcttggt
      841 gacctggatt ccccgtatga ttcccttcat cttagtcaag tataagggtt tgcctgcgat
      901 tgttgaacgt tttttgaagt tcttgcccgt ttctattatc tttgctttga ttctttcaag
      961 cgtagtgaca ggtaatgttg ggagtcttcc tcaaatcaaa tggctggact tcttagccat
     1021 ctttccaaca gcttgggtag cctttcgcta ccgcaatcta gtcggaacag ttctctttgg
     1081 agtggtctta attgcagtct tgcgtttggt cttttaaatt acccataaaa aaaacttatc
     1141 acagagatag atatcatata atggcgtaaa tgctcttttt ctgttaagat tataaggtat
     1201 tctattttgg aggaaatgac atgaaaaaaa tcgttaaata ctcatctctt gctgccctag
     1261 gacttgttgc tgcaggtgtg cttgcggctt gctcaggggg tgctaagaaa gaaggagaag
     1321 cagctagcaa gaaagaaatc atcgttgcaa ccaatggatc accaaggcca tttatctatg
     1381 aagaaaatgg cgaattgact ggttacgaga ttgaagtcgt tcgcgctatc tttaaagatt
     1441 ctgacaaata tgatgtcaag tttgaaaaga cagaatggtc aggtgtcttt gctggtcttg
     1501 acgctgaccg ttacaatatg gctgtcaaca atcttagcta cactaaagaa cgtgcggaga
     1561 aatacctcta tgccgcacca attgcccaaa atcctaatgt ccttgtagtg aagaaagatg
     1621 actctagtat caagtctctc gatgatatcg gtggaaaatc gacggaagtc gttcaagcca
     1681 ctacatcagc taagcagtta gaagcataca acgctgaaca cacggacaac ccaactatcc
     1741 ttaactatac taaggcagat ttccaacaaa tcatggtacg tttgagcgat ggacaatttg
     1801 actacaagat ttttgataaa atcggtgttg aaacagtgat caagaaccaa ggtttggaca
     1861 acttgaaagt tatcgaactt ccaagcgacc aacaaccgta cgtttaccca cttcttgctc
     1921 agggtcaaga tgagttgaaa tcatttgtag acaaacgcat taaagaactc tacaaagacg
     1981 gaacgcttga aaaattgtct aaacaattct tcggagacac ttacctaccg gcagaagctg
     2041 atattaaata atttcttgaa atcatccatt ctgagtaaga tgggtggttt ctcagttttt
     2101 agggatatag ttttaaacta tatatctgat tatctaataa caatttgtga aatcaaacaa
     2161 attgtgagat actagtacgg tattattttt aaggagaaag aatcatgaaa atcaaaaaat
     2221 ggcttggcct agcagccctt gctacagtcg caggtttggc tcttgcagct tgcggaaact
     2281 cagaaaagaa agcagacaat gcaacaacta tcaaaatcgc aactgttaac cgtagcggtt
     2341 ctgaagaaaa acgttgggac aaaatccaag aattggttaa aaaagacgga attaccttgg
     2401 aatttacaga gttcacagac tactcacaac caaacaaagc aactgctgat ggcgaagtag
     2461 atttgaacgc tttccaacac tataacttct tgaacaactg gaacaaagaa aacggaaaag
     2521 accttgtagc gattgcagat acttacatct ctccaatccg cctttactca ggtttgaatg
     2581 gaagtgccaa caagtacact aaagtagaag acatcccagc aaacggagaa atcgctgtac
     2641 cgaatgacgc tacaaatgaa agccgtgcgc tttacttgct tcaatcagct ggcttgatta
     2701 aattggatgt ttctggaact gctcttgcaa cagttgccaa catcaaagaa aatccaaaga
     2761 acttgaaaat cactgaattg gacgctagcc aaacagctcg ttcattgtca tcagttgacg
     2821 ctgccgttgt aaacaatacc ttcgttacag aagcaaaatt ggactacaag aaagcacttt
     2881 tcaaagaaca agctgatgaa aactcaaaac aatggtacaa catcattgtt gcgaaaaaag
     2941 attgggaaac atcacctaag gctgatgcta tcaagaaagt aatcgcagct taccacacag
     3001 atgacgtgaa aaaagttatc gaagaatcat cagacggttt ggatcaacca gtttggtaat
     3061 aagaaacagg gaggtgggag agagaattcc acctcttgct tttgtataga gcacggagtg
     3121 taaagaagac tattcgttca tagaaaggta gagagaatat ggtttttcct agcgaacaag
     3181 aacagattga aaaatttgaa aaggatcatg tagcccagca ttattttgag gttttgcgta
     3241 ccttgatttc taagaaatca gtctttgccc agcaggttgg actcaaggaa gtcgcaaatt
     3301 atctgggtga gattttcaag cgtgttggag ctgaagtgga gattgatgag agctatacag
     3361 cgccctttgt catggcacat ttcaagagtt cgcgtccaga tgccaagacc ttgattttct
     3421 ataaccacta tgacactgtg ccagcggatg gggatcaggt ctggacagag gatcctttta
     3481 cgctttcggt ccgcaatggc ttcatgtatg ggcgtggggt tgatgacgac aagggtcata
     3541 tcacagctcg cttgagtgct ttgagaaaat atatgcagca ccatgatgat ttacctgtca
     3601 atatcagctt tatcatggag ggagcggagg aatcggcttc aacagaccta gataagtatt
     3661 tggaaaagca tgcagacaaa ctccatgggg cggatttgtt ggtctgggaa caagggacca
     3721 aaaatgcctt ggaacaactg gaaatttctg gtggcaataa ggggattgtg acctttgatg
     3781 ccaaggtaaa aagcgctgat gtggatatcc actcgagtta tggtggcgtt gtggaaacag
     3841 ctccttggta tctcctccaa gccttacagt ctcttcgtgc tgcggatggc cgtatcttgg
     3901 ttgaaggctt gtacgaagaa gtacaagagc ccaatgaacg agaaatggcc ttgctagaaa
     3961 cttatggtca acgaaaccca gaggaagtta gtcggattta tggattggag ttgcctctct
     4021 tacaggagga gcggatggcc tttctaaaac gtttcttttt cgagccagcg cttaatatcg
     4081 aaggaatcca gtctggttat caaggtcagg gtgttaagac tattttgcct gcagaagcca
     4141 gtgccaagct agaggttcgt ctggttccgg gcttagaacc gcatgatgtt ctggaaaaaa
     4201 ttcggaaaca gctagacaaa aatggctttg ataaggtaga attatactat accttgggag
     4261 agatgagcta tcgaagcgat atgagcgcac cagccattct caatgtgatc gagttggcca
     4321 agaaattcta tccacagggc gtttcagtct tgccgacgac agcggggaca ggacctatgc
     4381 atacggtctt tgatgcccta gaggtaccaa tggttgcatt cggtctagga aatgccaata
     4441 gccgagacca cggtggagat gaaaatgtgc gaatcgctga ttattacacc catatcgaat
     4501 tagtagagga gctgattaga agctatgagt agagatatta tcaagttaga tcagatcgat
     4561 gtgacttttc accaaaagaa gagaaccatt acagcggtta aggatgtgac cattcacatc
     4621 caagaagggg atatctacgg aatcgttgga tattctggag cagggaaatc aacccttgta
     4681 cgggtgatta acctcttgca aaaaccatct gcagggaaaa ttaccattga cgacgatgtg
     4741 atttttgacg gcaaggtgac cttgacggca gagcagttgc gtcgtaaacg tcaagatatc
     4801 ggaatgattt tccagcattt taacctgatg agccaaaaga cagcagagga gaatgtagcc
     4861 tttgccctta aacactctga actcagcaag gaagaaaaga aggctaaagt agctaagttg
     4921 ttggacttgg ttggtttggc agatcgtgct gaaaactacc cttcacaact atctggaggg
     4981 caaaaacagc gtgtggcaat tgcgcgtgcc ttggccaatg atccaaaaat cttgatttca
     5041 gacgagtcaa cttctgccct tgaccctaag acaaccaagc agattttggc cttgttgcaa
     5101 gatttgaacc aaaaattagg cttgactgtt gtcttgatta cgcatgaaat gcagattgtc
     5161 aaagacattg ccaaccgtgt tgcagttatg caggatgggc atttgattga agagggtagt
     5221 gtgcttgaaa tcttctcaaa ccctaaacaa cctttgactc aagactttat ctcaacagct
     5281 acaggtattg acgaagccat ggtcaaaatc gagaagcaag aaatcgtgga acacttgtct
     5341 gaaaacagtc tcttggtgca actcaagtac gctggagctt caacagacga gccacttttg
     5401 aatgaattgt acaagcatta ccaagtaatg gctaatattc tctatgggaa tatcgaaatt
     5461 ctcgatggta ctcctgttgg agaattggtg gtggtcttgt caggtgaaaa agcagcgttg
     5521 gcaggtgccc aagaagctat tcgccaagca ggtgtacaac taaaagtatt gaagggagta
     5581 cagtaagatg gaatcattga ttcaaaccta tttaccaaat gtctataaaa tgggttgggc
     5641 tggtcaggca ggctggggaa cggctatcta cttaactctt tatatgacag ttctttcctt
     5701 cattatcgga ggcttcttgg ggctagtggc aggtctcttt ctcgtcttga cagcgccagg
     5761 tggtgtcttg gagaataaag tcgtattctg gattttagac aaaattacct caatttttcg
     5821 tgcggttccc tttatcatcc tcttggcaat cttgtcacca ctttctcact tgattgttaa
     5881 aacaagtatc gggccaaatg cagcccttgt cccactttct tttgcagtct ttgccttctt
     5941 tgcccgtcag gtgcaggttg tcttggctga attggatggc ggtgtcattg aggcggctca
     6001 agcgagcgga gcgactttct gggacatcgt gggtgtttac ctatcagaag gtcttccaga
     6061 tttgatccgt gtgacgactg tgaccttgat ttcccttgtt ggggaaacag ctatggccgg
     6121 tgcggttgga gctggtggta tcggtaacgt agccatcgct tatggattta accgctacaa
     6181 tcacgatgtg accatcttgg caaccatcat tatcattttg attatctttg caatccaatt
     6241 cttgggagat ttcttgacta agaaattgag ccataaataa aaaagagccg cgtggctctt
     6301 tttaactgat cagattttct gtgcaaattt tttactcaag gcttgtccaa tcaaggcacc
     6361 cactagggct ccgatgacaa tacttgcgat aaatagaagg acagttccag ggtttggagc
     6421 gaccatgatg cggtcgatat attcttggga ttttcctctt gccagaagag tagccatata
     6481 ggctttgggc gcaatccaca taagcaagat tggtcctgtt gtactaaagg cgaaaataat
     6541 gaaagaaagg aagttctttg ttttgtcctt gtattttcct aaatgagcta ctccatctgc
     6601 taggaggcca cagataattc caggaaggaa ggaaccagca ccgtgtttag ttcccaagaa
     6661 aaagagggca atgacaaggc cgatagtggt aatggctcca aagcgcggaa cttttgcgac
     6721 taggatcata tagacgctac cgccgacaag ggcagtaaag gcaggcgcat aaaacatgtt
     6781 tccagtttgg tcaaagagat tgcccaaaag gacaccaatc cccatgcaga ggaagtaaag
     6841 aactgcaaaa agcagtgtag ttaagataga tttcttcatg aattgtctcc tgataatttt
     6901 ttcacaattc tcattgtacc acggtttggt gggattgtaa atggatacta gaagtttttg
     6961 aaaacgcttg aaatatgata taatggtttc atagttattt ttaggggaat atcatgggta
     7021 gatttttaga ctttgtcttt aatcgtttct ttttagggat gattgcgaca gccttctttt
     7081 ggctattaac tttagtagga gggattatcc ttggtctagc gccagctagt gccaccttga
     7141 tgagcttata tgcagaacat ggttatagct ttcgggaata cagtttgaag gaggcttggt
     7201 ctctttacaa gcaaaatttt gtctcaagca acctgatttt ctatagcttt ttaggtgtgg
     7261 gtctagtttt gacctatggt ttgtatctct tggtgcaatt gcctcatcag accattgttc
     7321 atttgattgc gacccttttg aatgtcctag tagttgccct gatctttttg gcttatacag
     7381 tatctttaaa attacaagtt tattttgcct tgtcctatcg aaatagtctc aaattatcct
     7441 tgattggcat ctttatgagt ctagcagctg tggccaaggt tctccttggg actgtgctac
     7501 ttgtagcaat tggttactat atgcctgccc tgctattttt tgtaggaatt gggatgtggc
     7561 atttctttat cagtgatatg ttggaacctg tctatgaaat catccatgaa aaattggcga
     7621 caaaatagaa tgaagcactt ttggctacat acgcttctaa gaacctatag ttcagtgatg
     7681 atcattatca ttgcgagttt tgcaatctta ctctcttacg ctgactggga ttcacgtgaa
     7741 aaggaagccc agagagtagc ccagcgtgta actgctagaa cagtgagtga aattgaatat
     7801 taccatagag agtcaaccca gatagctcag gctttagttg aaaatcaagc tcgtattgag
     7861 ggaatctata aatactttag ccttagcatg ccagactatt tttactggca attagagcgg
     7921 aaagcttcgc cttatatatc agtctctctg tatgaaaatg ttgatgacct ctatgttcga
     7981 aatgattttg taactggagt ggccattgct tttcaagatt acaaggaagt ctatgtttct
     8041 actaaagaca aacgtagtgg agaaaaaatc agggctgagg atttcaaacc agcaggaaat
     8101 agttttgcca ttccggtgtc agatccagtg tcagatcaag atttaggagt gatttacatc
     8161 tccttggatc ctgctgtttt ataccatgcc attgataata ctagaggtca tactccgatg
     8221 gcagtaacag tgacctcacc ttttgatacg gagatttttc atattggtga gacagttgat
     8281 aaggagagtg aaaattggct agttggctta acttctcatg gatatcaggt tcaggtggca
     8341 gttcctaaaa actttgtttt acaaggaaca gtgactagct ctgctttgat tgtgggtttg
     8401 agccttctct ttattgtcat tctttatctg actttgaggc agacttttgc taattaccaa
     8461 aagcaggtag tggatttagt agaatccatt caagtcattg ctcaaggcga agaggggcgt
     8521 cggattgaca tttccgagaa agatcaggaa ttactcctaa tcgcggagac gaccaatgat
     8581 atgttggatc gattggaaaa gaatatccat gatatttacc agttagagct tagtcaaaaa
     8641 gatgccaata tgcgagcctt gcaggcgcaa atcaatcctc attttatgta taatacgctg
     8701 gagttcttac gcatgtatgc agttatgcag agtcaagatg agttggcaga tatcatttat
     8761 gaattcagta gtctcttgcg taacaatatt tccgacgaaa gagagaccct cctcaaacag
     8821 gaattagaat tttgccgtaa atacagctat ctctgcatgg ttcgctatcc caagtccatt
     8881 gcctatggtt tcaagataga tccagagtta gagaatatga agattcccaa gtttaccttg
     8941 caaccgctgg tagaaaacta tttcgcgcat ggtgttgacc acaggaggac agataatgtg
     9001 attagcatca aggctcttaa acaggatggg tttgtggaaa ttttggtggt cgataatggt
     9061 agaggaatgt cggctgaaaa gttggcaaat atccgagaaa aattaagtca gagatatttt
     9121 gaacaccaag ccagctacag tgatcaaagg aagtctatcg ggattgtcaa tgtacacgag
     9181 cgttttgtgc tctattttgg agaccgctat gccattacga tagagtctgc agagcaagcc
     9241 ggtgttcagt atcgtattac aattcaagat gagtagaaag ggagaaaatg tataaagtat
     9301 tattagtaga tgatgagtac atggtgacag aaggtctgaa gcgtttgatt ccctttgata
     9361 agtgggatat ggaggtcgtc gcaacagcca gtcatgccga tgaagctcta gaatatgttc
     9421 aggaaaatcc tgtcgatgtc atcatttccg atgtcaatat gccagacaaa acagggcttg
     9481 atatgattcg ggagatgaaa gagatcttac cagatgctgc ctatatcctg ctctcaggtt
     9541 atcaggagtt tgattatgta aaaagagcaa tgaaccttag tgtggtggac tatttggtca
     9601 aacctgttga taaggtagag ctgggaaatc tgctggagaa gattgcaggt cagctcggcg
     9661 agagagggaa gaaaagtcag actcttagtc aagaattaga cgaggctgga tttgttagtt
     9721 atttagggga taaggagaat tggtggatag gtctatccaa ggaaaaacaa ggttccttca
     9781 ccattcccta ctatgtcttg ggccaagact ggcagatttt catttctgac caacccctag
     9841 atggtttagt cgttacacct tttgaagctc cttatcaaga acactttgaa cgctggaagc
     9901 tgaatgctga gaaaaccctc ttttacggtt ctgtaaattt gcagcagtct gagagtctct
     9961 ttgcctatta cgaaccgatt tatagggtta tcattcaggg aaatctcaat caaatcgtag
    10021 aagagttaaa tctcttggag aaggtagttc ttgaaaatac gccgcgtgtt ccgattacta
    10081 aacagctttt tattcagttt gtcatggatg ttttccattt atttgaacat ctcaaagctg
    10141 atgacctgac agacatcgtc aaaaccattc atgctattca atccttcgat gaattggttc
    10201 cttatatcaa ggaaactctg accagctttt tcggtcaata ccgtatgaat gaaaatgtgg
    10261 tcagtgtgct ggaagtcatt ggtcgtgatt accaaaaaga gctttccctc aaggatatca
    10321 gtaaggctct ctttatcaat cctgtctatc tagggcagtt gattaagcgt gaaaccgatt
    10381 cgacttttgc agagttacta aacaaacaac gtattaaggc tgcccaacaa cttttgcttt
    10441 caactagtga cagcatcgaa gatatttgtt atgctgttgg ttacagtaac cttggatatt
    10501 tctataaagt tttccgaaag ttgtgcggaa aatcgccaaa agcctaccga aaacaggtag
    10561 aaactatact ataaaatttg tattccttta caaaaggtgc tataatatta tcaggaggtt
    10621 ctatcatgaa aaagaaacca atttatctat gggtcttgct aatcttgtct gcccttattt
    10681 cagttccgtc tctgtttgga attgtgagtc ccttgcctag taaagaagcc cttcgtgctg
    10741 ctcagaaaca agttgcaggg gtcaatgctc agcaattaga agaccagctt aattatacct
    10801 atagagtagc agaagcatct cattctattt ttaatgttgc tttgattgtg ctatctacta
    10861 ttttagtggt cgtagcgatt gtcttccttg ttcgtaaaaa tttgcaatat gcaaactata
    10921 cttacgttgg ctatgttttg ttagctatta ttggttcgat ttatggctat gttggtttac
    10981 aagacgctgt gcagttggtt caagatgaga gcatgcgttt gacagtgagt attggctcaa
    11041 aagctgttag cattttctat atcgtcatca atgttctctt cctagccctt gtcttctata
    11101 agatgtggcg acaacagaaa gccttggcag aagaagagga aacagaagag cttacctaag
    11161 tattgacaaa aaagaactat caagatacaa tcttggtagt tgttttttga ttatagataa
    11221 aatcatggag gtacatatga agacaatttc tttagtttat attagtttga gtggcaacac
    11281 tgaaagtttt gtgacgcgct tgaaagacta tctcttgtcc cagtacaaag ggattgaggt
    11341 tcaaaagatt catatcaagg atttggtcaa ggaaggcaaa aatttctatg aaatggacca
    11401 tccctatgtc gcttttttgc cgacctatct cgaaggtggg aatggcgtgg ataacggaga
    11461 tgttgagatt ttgacgacac cggtgggaga ttttattgcc tatggtaaca atgctagtaa
    11521 gtgttttggt gtggttgggt caggaaatcg taactttaat aaccaatact gcctaacagc
    11581 caagcaatac agtcaacgct ttggcttccc tgtattggct gactttgaaa tgcgaggcat
    11641 gctggaagat atcaaacatg tcgcagctat tatcgcagat ttgtatgagt tggaaaagga
    11701 gaattaatac tcaatgaaaa tcaaagagca aactaggaag ctagtcgcag gttgctcaaa
    11761 gcacagcttt gaggttgcag atagagctga cgtggtttga agagattctc gaatagtata
    11821 aagttcttat aagaggtggt tgaagttgtt caactgtttt ttgagtataa acagtcttta
    11881 agaacgtaaa aaagcataag ttcaggtctt caaaaccttg ttcttatgct ttttatcata
    11941 gaaatatttg ctgaattttc tcttgaaatg aaaccttatc ttcatctcgc gcttgtccct
    12001 taccctgctt ttccgattgc gagtgcgtag ataaagaaga tggcgaagcc aaagaggaaa
    12061 atcaatcccg caatggcaag gtgtttgagc caagaaggaa gatttttgtt ttcacgcgtt
    12121 accaaggcgt aattcaaaag agcaaagaaa ggtgttgtca ggaaagatcc aatcatggca
    12181 aagcggagca tggttgaaac ctgaccagcg aagaacttga taatgacgat accgatgata
    12241 gcagtgatgg tcatccagat gttcaaagat ttacgattgt cctctttttg actgattagc
    12301 agtcggagag attcctgatt aacgcgagaa tagccatcga taacagttat aactgttcca
    12361 aagatacaga ggaaggcaat aaaggtaatc aagtaacggg accattcgcc aagaacagag
    12421 gcatacatgc ccacgaattg agagatgtat ttggctgaag cagcttcaac cgcctgccct
    12481 gtaggatact gaatcagtgc tcccagtgcc acaaagaaga cggctaggat agctgttcca
    12541 atataaccag tgttaaagtc aaacagagcg tcttctgtgt taaagttgac ggtctttctc
    12601 ttttcagctg accaaagtga attgatggct gaaatttcaa taggagccgg catccatcct
    12661 aggagggaga cgatgaaggg cagagctgcc atttgccaag gtgtcttctc gacaaaatca
    12721 gaactgtatt ctggatgctt gaccgccgca atgataactg caagaacagt cgcaatggtt
    12781 aaggcagaca taatccattt gaccatgccg tctaaaagtt tgtagcctcc aaagagtagc
    12841 atagcccaaa tgattgcaac gagaatgagg gaccactgag taatgctaag tccaatcatt
    12901 gggaaggcac tggcgatgat agctgagcac agaatggcaa caccagccgt gttgaccata
    12961 gccgaaaaga cattgagaat aaagaaaatc cagagataga gttttccttt ttcggcataa
    13021 ccttcaacca aagtctttcc agtatcagct gtgtattcag caccaaaacg gaaaaatgga
    13081 tatttaaaga cattggctaa gatgaccaag agaagtagag accaaccgta agaaccgcca
    13141 gcttgagttg aggatacaat gtgggaacct ccaacagcgg cagttgccat taggattcca
    13201 ggtcccattg cttttagctt gcttgcccag gttgattgat ttaaggaaat agcttgcgac
    13261 atgataaata ctcctttttg aattttcaga ataatctgta tatgcaatct atattctaca
    13321 aaaaattttg gaaaaatgca agaatatttt gaaaaaagat agaaaattta caaagaaaat
    13381 ctgaaataac tgttatgata tagcagattg aaactagaat agtacacttt tacttctaaa
    13441 acattgttag aaatcgattt gactgtcctg attgatttat cctgttctta tttcatttca
    13501 ctatagtaag gtgcagcagg ataaagcaaa accgagaagt ttctttctcg gttttgctta
    13561 ttatgaggtt cctattttct atgctccaag agttgattga tgtgatctac ttttttagcc
    13621 tctcttttat agagaatagc ccagatgatg agatagacaa tcgcaaactc gataatgagc
    13681 tggaggtaga aaatccagtg gaaggggaac caaccagcaa gagttgctag tgggacaaag
    13741 ccagccagca taaggaagaa atgagtcaga gtggcacgaa gcatgctcca gtcacggctg
    13801 aataagcggt tgccaaagtt gaagagcata ccgatggctg cccagataag tgtgcagtag
    13861 agcaagacca gggcaccgtg aacctgatgc tgatccatca cttggccgat gagagagtag
    13921 ggatttagtg gtgcgtaggt atttggtgca taaatgagtg aaaagaggat ggagaggatg
    13981 aggccgataa gaacaccggc agctgcatcg tgaaatactt gttttttcat agttctaatt
    14041 tctccttgat ggtttttaga taacggcgtg aagagtaggt gaagctttcg tttttcaaga
    14101 aaatttctac cagaccgttt ggcgtgagct tgaggtgaga gatggaatcg atattgatga
    14161 tttctgattg ggaaatttgg ataaaattgg ttggcaagag tttaagaacc tgatagagtc
    14221 gcaaatcaat gctgtaggtc tgactcgcgg tttctgctag aaccttccga ttctcgatat
    14281 agaagcgctg aatcttgcca atctcaacta gatagacctg atcatcgatt tttcctttga
    14341 ttttttctct ttggtccaga ttttctgcga actcgatgac tttctggact ttttcggttt
    14401 cttgaggtgc ttggacaatc agcttttcct cctcgtaagt ctcactaatc tgtagttcta
    14461 ctttcataaa tttctctcct tgtttttcat acaaaattaa tctcacttct tgtacacctt
    14521 tattaatact cttcaaaaat ctcttcaaac cacgtcagcg tcgtcttgcc gtaggatagt
    14581 tgttgacttt gtcagtttta tctacaacct caaaacagtg ttttgagctg tctgcgtcta
    14641 gctttctagt ttgctctttg atttttattg agtataccac tattttactc cctctggcaa
    14701 gggactttgt ctatgtggag ggattgggct cctatgtggt ggagtttttc tgttctttct
    14761 gaaatatggt ataatagcac taattaattt ctaggaaaat agatacagaa aggggctgaa
    14821 agatgtctca tattattgaa ttgccagaga tgctggcaaa ccaaatcgca gctggggagg
    14881 tcattgaacg tcctgccagt gtggttaaag agttggtaga aaatgccatt gacgcgggct
    14941 ctagtcagat tatcattgag attgaggaag ctggtctcaa gaaggttcaa atcacggata
    15001 acggtcatgg aattgcccac gatgaggtgg agttggccct gcgtcgccat gcgaccagta
    15061 agataaaaaa tcaagcagat ctctttcgga ttcggacgct tggttttcgt ggtgaagcct
    15121 tgccttctat tgcgtctgtt agtgtcttga ctctgttaac ggcggtggat ggtgctagtc
    15181 atggaaccaa gttagtcgcg cgtgggggtg aagttgagga agtcatccca gcgactagtc
    15241 ctgtgggaac caaggtttgt gtggaggatc tctttttcaa cacgcctgcc cgtctcaagt
    15301 atatgaagag ccagcaagcg gagttgtctc atatcattga tattgtcaac cgtctgggct
    15361 tggcccatcc tgagatttct tttagcttga ttagtgatgg caaggaaatg acgcggacag
    15421 cagggactgg tcaattgcgc caagcaatcg cagggattta cggtttggtc agtgccaaga
    15481 agatgattga aattgagaac tctgacctag atttcgaaat ttcaggtttt gtgtctttac
    15541 ctgagttgac tcgggctaac cgcaattata tcagcctctt catcaatggc cgttatatca
    15601 agaacttcct gctcaatcgt gctattttgg atggtttcgg aagcaagctt atggttggac
    15661 gttttccact ggctgtcatt cacatccata tcgaccctta tctagcggat gtcaatgtgc
    15721 atccaactaa gcaagaggtg cggatttcca aggaaaaaga actgatgacc ctggtttcag
    15781 aagctattgc aaatagtctc aaggaacaaa ccttgattcc agatgccttg gaaaatcttg
    15841 ccaaatcgac cgtgcgcaat cgtgagaagg tggagcaaac tattctccca ctcaaagaaa
    15901 atacgctcta ctatgagaaa actgagccgt caagacctag tcaaactgaa gtagctgatt
    15961 atcaggtaga attgactgat gaagggcagg atttgaccct gtttgccaag gaaaccttgg
    16021 accgattgac caagccagca aaactgcatt ttgcagagag aaagcctgct aactacgacc
    16081 agctagacca tccagagtta gatcttgcta gcatcgataa ggcttatgac aaactggagc
    16141 gagaagaagc atccagcttc ccagagttgg agtttttcgg acaaatgcac gggacttatc
    16201 tctttgccca agggcgagat ggactttaca tcatagatca gcacgctgct caggaacggg
    16261 tcaagtacga ggagtaccgt gaaagcattg gcaatgttga ccagagtcag cagcaactcc
    16321 tagtgcccta tatctttgaa tttcctgcgg atgatgccct gcgtctcaag gaaagaatgc
    16381 ctctcttaga ggaagtgggc gtctttctag cagagtacgg agaaaatcaa tttattctac
    16441 gtgaacatcc tatttggatg gcagaagaag agattgaatc aggcatctat gagatgtgcg
    16501 acatgctcct tttgaccaag gaagtttcta tcaagaaata ccgagcagag ctggctatca
    16561 tgatgtcttg caagcgatct atcaaggcca atcatcgtat tgatgatcat tcagctagac
    16621 aactcctcta tcagctttct caatgtgaca atccctataa ctgtcctcac ggacgtcctg
    16681 ttttggtgca ttttaccaag tcggatatgg aaaagatgtt ccgacgtatt caggaaaatc
    16741 acaccagtct ccgtgagttg gggaaatatt aaaagtataa aaaagtctgg gaaaaatttt
    16801 caaaatcaga aaaacgcata aaatcaggtg ttcaaaaacc ttgattttat gcgttttatc
    16861 atggaaatag ttacttcatg ttttcctaat tcttttcgaa actcttttta aaccacgtca
    16921 gttttatcag taatctcaaa acagtgtttt gagctaattt tgccagtttt gtctgtaaca
    16981 tcgaagttgt gttttaccac tctgcgactg gtttcctagt ttgctctatg attttcacag
    17041 agtattaaaa tgcgattttg ccaagtttct ttattcgtct aaaagtagag tctgttctat
    17101 gcgtctaatg tacgaattag gttgaccatt tcaatagctc cttgtgcaca ctcagaaccc
    17161 ttatttcctg ctttggtacc agctcgttct atggcttgtt caattgtatc tgtcgttagc
    17221 acaccaaaca taacaggaat ttcgctattt aaactgattt gggcgattcc cttagatacc
    17281 tcgctacata cataatcata atgacttgta ttccctctaa tgacagctcc caagcagata
    17341 attgcatcat attttttact ttttgccatt tttgatgcaa tcagtggtat ttcaaaagct
    17401 cctggaaccc aggctacctc tatatctttc tcgtttacat tctctctttt gagattatct
    17461 agtgctccag ataataattt tgaagttata aattcattaa atctcgctac aacaatacct
    17521 attttaatat tgtttgctac taaattacct tcataagtgt tcatttattt ttcctccata
    17581 tttaaaatgt gacccattcg atttttcttt gtttctaaat aaaaactatc gtaaggattg
    17641 gcttctattt cgattgatat tctactggaa atggtaattc catatttttc taactgttca
    17701 accttgtcag gattatttgt cagtaaatga agtgactgaa gtcccagatc tttaagcatt
    17761 tgtgctccaa tatgatattc tcttaaatca ccttcaaagc ctaatgcaag attggcatca
    17821 agcgtatcca tgccttgatc ttgtaaatga taggctttta atttattgat aagtccaatt
    17881 cctcgtccct cctgtcgcaa gtaaagtaag acacccgaac cattctcaac aatcattttc
    17941 atagctttat cgaattgctg tccacaatcg caacgtaaag agcctaaaac atctcctgtt
    18001 aaacattcgg agtggacccg acataataca ttggcttcat cctctatgtt tcccataata
    18061 agagcaagat gatgttcccc atttagttta tctatatagc taattgcttt gaaattaccg
    18121 tatctagtag gcatattgac agttgaaact cgttctacca gctgatcata tacttttcta
    18181 tattcttgta attctttgat ggtaattagt ggaatgttgt gtttcttcga aaactgaatt
    18241 aaatcatctg ttctcatcat tttgccatca tgattcatta tttcacaaca taggccacac
    18301 tcttttagtc cagctaattt taataaatca acagttgctt ctgtgtgtcc atttctttct
    18361 agaacaccac ctttttttgc aattaaagga aacatgtgtc ctggcctgcg aaaatcagag
    18421 ggtgttatat cttcagctac acacatacgt gcggtcagtc ctctttcctc ggcagaaata
    18481 cctgtggtcg tttctttata atcaattgaa actgtaaaag cagtcttatg attatctgta
    18541 ttgttttcaa ccataggtga aagcattaat tgattagcta aactttcgct cataggcata
    18601 caaattaatc ctttggcata agtagccata aaattaacat tttctgttgt agctgcttgt
    18661 gcagaacaaa ttaagtctcc ttcattttct ctatccttgt cgtctataac aagaacaagt
    18721 cgtcccttct gcaatgcttc taatgcttct tgtatttttc gatattccat tgactgatta
    18781 tcctttctgc taaaatccat tttgatataa tagttcctta gatatttctg attttggaga
    18841 gttatccatc agtttttgca catatttacc taagatatca ttttcaagat ttactgtact
    18901 cccgacttgt ttactcttaa gaatggtttg ttccaaggta tgagggataa cagatactga
    18961 aaagtttact ttggagactt tagcgacagt cagactaatg ccgtcaattg taatagatcc
    19021 tttttcaact attaaatcta aaatttcttt ttgtgtgttg atttgatacc atacagcatt
    19081 atcatctttt tttattgacg agatttttcc tgtaccatca atgtgtcctg taacgacgtg
    19141 acccccaagt cgaccgttga cagataaggc tctttctaga ttcacctcac ttccatgttt
    19201 taatagagta agagctgttc gactccatgt ttcattcatt acatcaactg taaaggattg
    19261 atggttgaaa tgagtaactg taagacagat accatttact gctatactat cgcctaaatg
    19321 gatatccgtt aatatttttg aggctttaat tgatagttta caattacgag agtctttctg
    19381 tattctttca acttttccga tttcttcaat tattcctgtg aacatggata aatcacttca
    19441 ctttctatga gatagtcatt tcctatttga gaaaaagcat aaggtttcaa tctaatagcg
    19501 tcatttggca aagaaatgcc ttcacctccg acaggaaact tggcactgcc tccaaaaatt
    19561 tttggtgcaa tatatatttt cagctcatca acaatttgtt gttccaaagc actccaattc
    19621 attagactgc ccccttctag aactaggcta tcaatctgca tgtttcctag atgttgcatt
    19681 aaactcgata agtctatatg attgcctttt ttctttatgg aaagtatttc acagccatga
    19741 ttttgatata gcttcatttt atttttgtct tcagaggaag tggcaatgta agttttaata
    19801 tcatttgctg tttttacgat tttagaggta agaggagttc gtaaatgtgt atcgcatatg
    19861 atacggatag gatttttccc ttcctccaat ctacatgtca gcaaaggatc gtcttgaata
    19921 acagtattga ctcccaccat aattgcacta acatggtgtc gtaactgatg cacatgcttt
    19981 cttgcttctt cttcagtaat ccatttggat tgatttgttt tagtggctat ttttccatcc
    20041 attgacattg catatttcat aaaaacatag ggtacatgct gggtaatata ctttctaaaa
    20101 ctttttatta agttaagaca ctcattttct aaaattccaa cagtaacttg aagattattt
    20161 tcctcaagta tctttactcc ttttccagat acaataggat tacagtctag gcttccaatg
    20221 actactcttg taataccact atcgattata gcatctatac agggaggtgt tttcccgaag
    20281 tgacaacagg gttcaagtgt tacataaagc gtcgctccga caggggattc tctacagttt
    20341 ttaagagcat ttctctcagc atgtgggcca ccaaaaaact catgataacc ttgtccgatg
    20401 atgtgattat cttttacaat aactgcgccg accataggat tgggattgac gtaaccagcc
    20461 cctttttgtg ccagttttat tgctaatttc atatattttg aatcgctcat ctcactacct
    20521 ccaaaaaaat atgccttgaa taggggacta ctcaaggcat acaaaagaaa acttatgcga
    20581 ttaacaaaaa tgctctgaaa tgacaagtaa tcatttcaga gcacgcaaaa agcacaaata
    20641 tacttttatc ttctttcatc cagactatac tgtcggcttt ggaatttcac caaatcatgc
    20701 ctttcggctc gtgggctata ccaccggtag ggaatttcac cctgccctga agatagttat
    20761 tcaattacag atgattatag tacttaattt tgaatatgtc aacagataaa taccgattgt
    20821 ttttgatata ctgtatttgt gataatcgat tctcgctcct cggataaaga aaatatgata
    20881 tactagataa acgaaataag agagaaggaa tactatgtac gcatatttaa aaggaatcat
    20941 taccaaaatt actgccaaat acattgttct tgaaaccaat ggtattggtt atatcctgca
    21001 tgtggccaat ccttatgcct attcaggtca ggttaatcag gaggctcaga tttatgtgca
    21061 tcaggttgtg cgtgaggacg cccatttgct ttatggattt cgctcagagg atgagaaaaa
    21121 gctctttctt agtctgattt cggtctctgg gattggtcct gtatcagctc ttgctattat
    21181 cgctgctgat gacaatgctg gcttggttca agccattgaa accaagaaca tcacctactt
    21241 gaccaagttc cctaaaattg gcaagaaaac agcccagcag atggtgctgg acttggaagg
    21301 caaggtagta gttgcaggag atggccttcc tgccaaggtc gcagtgcaag caagtgctga
    21361 aaaccaagaa ttggaagaag ctatggaagc catgttggct ctgggctaca aggcaacaga
    21421 gctcaagaaa atcaagaaat tctttgaagg aacgacagat acagctgaga actatatcaa
    21481 gtcggccctt aaaatgttgg tcaaatagga gcagagaatg acaaaacgtt gttcgtgggt
    21541 caagatgacc aacccactct acatcgccta tcatgatgag gagtggggcc agcccctcca
    21601 tgatgaccaa gcgttgtttg agttgttgtg tatggaaacc tatcaggcag gcctgtcttg
    21661 ggaaacggta ctcaacaaac gccaagcttt ccgagaagcc tttcatagct atcaaattca
    21721 ctcagtcgca gagatgactg acactgaatt ggaagccatg ctggagaatc cagctatcat
    21781 tcgaaataga gccaagcttt ttgctacacg cgctaacgcc caagtctttc tacagttaca
    21841 ggcagagtac ggctcttttg atgcctatct ttggtctttt gttgagggga aaactgtcgt
    21901 taacgatgtt cctgattatc gccaagcgcc agctaaaaca cccttatctg agaaattagc
    21961 caaagatctc aaaaaacgag gcttcaagtt cacaggccca gtcgccgtat tgtcttttct
    22021 acaggctgca gggctagttg atgaccacga gaatgattgt gagtggaaag gtcttaaatg
    22081 atgtctaaca aaaataaggg aattctgatt tttgcgattc tctatacagt cctctttgtg
    22141 tttgatggcg ttaaattgct ggcttcttta atgccatctg tcattgcaaa ttatcttgtt
    22201 tatgtagttt tagctttata tggctccttc ttgttcaagg atagattgat ccaacaatgg
    22261 aaggagatta gaaagactaa aagaaaattc ttctttggcg tcttaacagg atggctcttt
    22321 ctcattctga tgactgttgt ctttgaattt gtatcagaga tgttgaagca gtttgtgaga
    22381 ctagatggac aaggtctaaa tcagtctaat attcaaagta cctttcaaga acaaccacta
    22441 ctgatagctg tttttgcttg tgtcattgga cctctggtag aagaattatt tttccgtcag
    22501 gtcttattgc attacttgca ggaacggttg ccaggtttac taagcattat tatggtagga
    22561 cttgtttttg ctctgactca tatgcacagt ttggccctat cagagtggat tggtgcagtt
    22621 ggttacttag gtggaggcct tgccttttct attatttatg tgaaagaaaa agagaatatc
    22681 tactatcccc tacttgttca catgttaagc aacagcctct ccttaatcat tttagctatc
    22741 agtatagtaa aatgaaataa gaacaggaca aatcaatcag gacagtcaaa tcgatttcta
    22801 acaatgtttt agaagtagat gtgtactatt ctagtttcaa tttgctgtaa tatgtgatga
    22861 aaatgccagt aatgataccg agaaaaagct gagaaacttt tcccagcttt atttgttata
    22921 gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa agggtataat
    22981 tgctcttgga gttgcgtggc cgacattcag attatagaca atcgggatat tgctgtcaat
    23041 gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag gttttccgac
    23101 caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca acatcttttt
    23161 gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt tcccttccca
    23221 gtctgacaag tcagggaaaa gtttgtattt ttggcagagc tccgtgctat ctgcgtatcg
    23281 agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt tcccctcgaa
    23341 ttgggccctt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac gaggtgttcc
    23401 cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag ggcggatttc
    23461 tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg ctagcatttc
    23521 tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct tgattcctaa
    23581 tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa ttttttgctt
    23641 gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat aggtatcgtc
    23701 tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat gaatcaaatc
    23761 ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg aatggggcaa
    23821 aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca cttcgtgttt
    23881 gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag tagaaaccat
    23941 atctcatcct cctagaaata gattgagcct attttatcac aaaatataag agaaagctat
    24001 gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac cacgtcagtt
    24061 ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct agtttgctct
    24121 ttgattttca ttgaatataa ctcaaaaaag taagtgaaaa agcaaccgca cctgcagttg
    24181 cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact acggatattc
    24241 aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat agctagtggc
    24301 aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa gaagacaagc
    24361 aaccaaagga acatagaagc taggataact agtacagatt tccagaaagg tggacgttga
    24421 ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa gtagaaggca
    24481 aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa agcttggtct
    24541 gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat gaaaagagct
    24601 gagtccataa tcatcagttt tgggtcatca ttttcttttg gatgctcttt ttcgtactgc
    24661 tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga acgggcagtt
    24721 gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat agtctggatt
    24781 tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac aaactcttgg
    24841 tttttcttag ttaatttttg tagatcaatt tgagacatag gaactcctct tagaaccatt
    24901 ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata aagacgatta
    24961 accagaaggc atttggctct ccgtttaggg ggatttcatt atccttaaag ttcatcccgt
    25021 aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc aaggttttca
    25081 tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata gaatgcaaga
    25141 cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg gtgtcttcaa
    25201 gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc aatttcttaa
    25261 tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt tccaattcca
    25321 tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg atttgttcac
    25381 tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga taaagaattt
    25441 gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg ttgataaaga
    25501 catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca gtgatgataa
    25561 taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg accggcacgt
    25621 ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct tccgcatcga
    25681 gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg agtgattcat
    25741 tttgagtcgg attgacgaga ttgatccaag tacccggttc aagagtatcg atctctttaa
    25801 attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct catttttcag
    25861 attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata gaatctcact
    25921 ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca agataaaatt
    25981 gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat tccgcgagac
    26041 aagttggttg tcgtgactgg cttgtcaggt tcagggaagt ccagtctggc ttttgatacc
    26101 ctctatgcgg agggacaacg tcgctatgta gagagtttgt ccgcctacgc tcgtcagttc
    26161 ttgggaaata tggaaaaacc agatgtagat gccattgatg gtctcagccc agctatttcc
    26221 atcgaccaga aaacgactag taaaaatcct cgctcgacgg tgggaacgac gactgaaatc
    26281 aatgactatc tgcgtctcct ctacgcacgt gtggggacgc cttactgtat caacggacat
    26341 ggagctatca atgcttcttc tgtggagcaa atcgttgata aggttttgga gttacctgaa
    26401 cgccagcgct tgcagatctt ggctcctgtc atccgcaaga aaaaaggcca acataagagt
    26461 gttatcgaga aggttcagaa agacgggtat gttcgtgttc gtgtggatgg ggaagtctat
    26521 gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga tgtcgtggtt
    26581 gaccgtattg ttatcaagga gggcattcgt agccgtctct ttgattccat tgaagctgcc
    26641 cttcgtatcg cagaaggtta tgtgattatc gacaccatgg acgactctga gttgttgttc
    26701 tctgagcatt atgcctgtcc agtttgtgga tttactgtcc cagagttaga acctcgtctc
    26761 ttctctttca atgctccctt tggctcttgt agtgagtgtg acggcttggg gattaagctg
    26821 gaggtggata ctgatttggt agtgccagat gccagcaaaa ccttacatga gggagcgctg
    26881 gcaccttgga atcctatctc atccaactac tatccaaaca tgttagagca ggccatgaaa
    26941 gtctttggag tggctatgga taagcctttt gaggacctgt cagaagaaga taagaacttg
    27001 attctctacg gctcagatgg taaggaattc catttccatt atgaaaatga atttggtggt
    27061 gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg tcgttaccat
    27121 gaaaccaata gcgattacac tcgcactcag atgcgtctct acatgaatga gctgacctgc
    27181 ggaacctgtc aaggctatcg tctcaatgac caggccttgt ctgtccgtgt gggcggccag
    27241 caagggccac atattggaga aatctcagac ctgtctatcg ctgaccactt ggacttggtg
    27301 agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct caaggaaatc
    27361 aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct gtcacgttca
    27421 gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca gattggttcc
    27481 aacctatcag gtgtcctcta tatcctagac gagccgtcaa tcggtcttca ccagagggac
    27541 aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac tcttatcgtg
    27601 gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt tggtcctggt
    27661 gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt ggctcgcaac
    27721 agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt accagaagag
    27781 cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa caacttgcaa
    27841 aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt gtcgggttca
    27901 gggaaatcga ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa gctcaaccgt
    27961 aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt cgaccgtttg
    28021 attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc tacctataca
    28081 ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa gattcgaggc
    28141 tacaagaagg ggcgcttcag tttcaacgtc aagggaggtc gctgtgaagc ttgctcaggt
    28201 gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc ttgtgaagtt
    28261 tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga aaagaatatt
    28321 tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca cattccgaaa
    28381 attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac cttgggacag
    28441 ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag cgaactccac
    28501 aaacgctcga caggaaaatc tttctacatt ctggatgagc cgacgacagg gcttcataca
    28561 gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg caatacagtc
    28621 ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat tgacttggga
    28681 cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga agaagtagct
    28741 gccaacgaag ccagctatac aggacactat ttgaaaggaa agttacatca tgaataaacg
    28801 cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtgtca tcatcaacaa
    28861 tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag tctttatcag
    28921 ccgtgaccgt caggtcttag tgacagactc tcgctatatc atcgcagcta agcaagaaac
    28981 cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag gaattgttaa
    29041 ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtgtctt attaccaccg
    29101 tatgcaggca gcttttgcag gtttggactt gcttccacaa actcagtttg tggaaggtct
    29161 tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt ctatctcaga
    29221 ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa ttgagattgc
    29281 caacttcctt gatttccgca tgcgtgagtt gggagcatct ggcttatctt ttgatacgat
    29341 cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca aaccagtgga
    29401 gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg tcagtgatat
    29461 gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt acaatacggt
    29521 tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt tccgtgactt
    29581 tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggcgactact ttactcacgg
    29641 cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagcc agacttctac
    29701 agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata tcgaaggcaa
    29761 atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg aattattgac
    29821 cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag tacgaaaatg
    29881 acgaaaaaag tcaaaaaaaa ttaaaaatag gtcgcaagtc ggatgttttt tatggtataa
    29941 tagactaaac tgatagtaac atgtagcgaa aggggtaggt acatgattaa aatttataca
    30001 gtctcaagtt gtactagctg taaaaaagca aaaacctggc tcaatgccca ccagttaagt
    30061 tataaagaac aaaaccttgg taaagaagga attacgagag aagaattact ggatattcta
    30121 accaaaacag ataacggaat agccagcatc gtttcgtcta aaaatcgcta tgccaaagcc
    30181 cttggagtgg atattgaaga tttgagtgtc aatgaagttc tcaatctgat tatggaaaca
    30241 ccgagaattt taaagagccc aatccttgta gatgaaaaac gcctgcaagt tggctacaag
    30301 gaagacgata ttcgtgcctt cctaccacgc tctgtccgta atgtagaaaa tgcagaagca
    30361 cgtttacgtg cagctctata aacatcaagg ctgggagcac ttcccagtct tattctattt
    30421 taatttcaaa aagaaagaag agagaaatga aaaaaatagt tcttgttagt ctagctttcc
    30481 tttttgtcct ggttggttgc ggacagaaaa aagaaactgg aacagctaca aaaacagaaa
    30541 aggatacgct tcagtcggca ttgccagtta ttgaaaatgc cgagaagaat acagttgtaa
    30601 ccaagacttt ggtcttgccc aagtcagatg atggtagcca gcagacacaa acaattactt
    30661 acaaagacaa gacttttttg agtctaacta tccaacaaaa acgtccagtc tctgatgagt
    30721 tgaagactta tattgaccaa catggagtgg aggaaactca aaaagctctt cttgaagcgg
    30781 aggagaagga taagtctatc attgaagctc gtaaattggc aggtttcaaa cttgaaacaa
    30841 aactattgag cgcaacggaa cttcaaacaa cgactagttt tgattttcaa gttctggatg
    30901 tcaagaaggc ttcccagttg gaacatctga agaatattgg tttggaaaat cttttgaaaa
    30961 atgaaccaag caaatatatt tcagatagat tggcaaatgg cgcgacagaa caatagaaaa
    31021 tccaaataaa tagactgcct gaattgtaga aggtaaggaa ttatgctata atggtactat
    31081 tctaaggaaa gagggtgtta gaatgggatt tactgaagaa acagtacgtt ttaaattgga
    31141 cgattccaat aaaaaagaaa ttagcgaaac tttgacagat gtttatgctt cgttgaacga
    31201 taagggttac aacccaatta accaaatcgt aggttacgta ttgagtggag accctgccta
    31261 cgttcctcgt tataataatg cacgaaatca aatccgtaag tatgagcgtg atgaaatcgt
    31321 tgaggaattg gttcgctact acctcaaagg acaaggagtc gatctataac ctatgagaat
    31381 tatgggattg gacgtcggtt caaaaacggt aggggtggcg attagcgatc cgcttggttt
    31441 tacagctcaa gggcttgaaa tcatccagat aaatgaagaa caaggccaat ttggttttga
    31501 ccgcgttaag gaattggttg atacttacaa ggtggaacga tttgtagtgg gcttgcctaa
    31561 aaacatgaac aatacaagtg gaccgcgcgt agaagctagt caagcctacg gagcaaagct
    31621 agaagagttt tttggtttac cagtagacta tcaggatgaa cgcttgacaa cagtggctgc
    31681 tgagcgcatg ttgattgaac aagcagatat cagtcgcaat aagcgcaaga aagtcattga
    31741 taagttagca gctcagctga ttttacaaaa ttatttagat agaaaatttt aatataaagg
    31801 agaggctatg tcacacgatc ataaccacga ccacgaagaa cgtgaactaa tcacactagt
    31861 agatgagcaa ggaaatgaaa ccttgtttga aatccttttg acaattgatg gaaaagaaga
    31921 atttggtaaa aactatgttc ttctagtacc agttaacgca gaagaagacg aagacggaca
    31981 agttgaaatc caagcttact cattcattga aaatgaagat ggaacagaag gcgaattgca
    32041 accaatccca gaagactcag aagacgaatg gaacatgatt gaagaagtct tcaacagctt
    32101 tatggaggag tgatacagtc tgggagactg tatcagccca actcccagaa atggggaaga
    32161 gttggaacgt ccagtgaaca tttttacccc aactcttaga aattgagaag agttggaaca
    32221 tctagtggat gtttttagcc catattcaca ttcatagtgg ctagttatta gctaaccagg
    32281 taagaggtcg ggacgaaaat cctggccttg tttttattag taaccatact ttaatgcgat
    32341 aattgattgg acttttgtca aggagatgtg tatgtttgaa gtagaagaat ggcttcatag
    32401 tcggattggt ttgaattttc gatcaggttt gggccgaata cagcaagcgg tggatttgtt
    32461 aggaaatcct gagcagtctt accctattat ccacgtaaca gggactaatg ggaaaggatc
    32521 taccattgct tttatgaggg aattatttat ggggcatggc aaaaaagttg cgacctttac
    32581 ctcccctcat atcgtctcta tcaatgaccg aatctgcatt aatgggcaac ctatagcaga
    32641 cgcagacttt atccgtttgg ctgatcaggt caaggagatg gagaaaacgc ttctgcaaac
    32701 tcctgaccag ttgtcctttt ttgaattgct gaccttggtt gcttttcttt attttaggga
    32761 gcaagaggtg gatttggttt tattagaagt gggaattggt ggcttacttg acacgaccaa
    32821 tgtggtaact ggagagcttg ctgtcatcac ctccattggg cttgaccatc aagaaacctt
    32881 gggtgatagt ctagaagcaa ttgcagagca gaaagctggt attttcaagg ctggtaagaa
    32941 ggcagtgatt gcgaaattgc atccagaagc taggcttgtc tgtcagaaaa aagccgaatc
    33001 tttagctgtt aacctttatc aggcaggtca agatttttta atgctgaatg gtgatttttc
    33061 aagctcttta ctaaatcttt cacagctgaa cataggctta gaaggagtct atcagcagga
    33121 gaatgcagcc ttggcgttgc aaacttttct tctttttatg ggagaaggaa aggaagctgt
    33181 tgatgaacag gctgtaagaa aggccttgga acagacccat tgggctggtc gcttggagcg
    33241 tattcgccca cagatttact tggatggtgc tcataacctc cctgccttga ctcgcttggt
    33301 tgagtttatc aaagaaaaag agcaggaagg ctatcgacct caaatcctct ttggatcctt
    33361 gaaacgtaag gattatcaag ggatgttggg ttatctgact gaaaatttac ctcaagtgga
    33421 actcaaaatg accgactttg actatcaagg gtctttggac gagacagatg taacaggtta
    33481 ccatgtaatt ccctcttacc gagaatttat cagcagtttc gaagaaaggg cagacgctca
    33541 agacttgctg ttcgttacag ggtctctcta ttttatctca gaagtacggg gctacctgct
    33601 ggaccgtgag cagataaatt gacccccttt tttgaacttg ttatactagg ggaattgctg
    33661 gttagagaaa atttctctaa attggtagca gaaaggaaat tcatcatgaa attaaaaaga
    33721 ttcacacttt ctcttgcttc tctagcaagt tttagtctct tagtagcttg ttcacaaaga
    33781 gctcaacagg ttcaacagcc tgttgctcag cagcaggtcc aacagcctgc tcaacaacct
    33841 gctcaacaga ataccaatac tgcaaatgca ggaggtaacc aaaatcaagc ggctccagta
    33901 caaaaccaac ctgttgctca accgaccgat attgatggga cttatactgg tcaggatgac
    33961 ggagaccgta tcactttagt ggtaactgga acgactggta catggactga gctcgaatct
    34021 gacggggatc agaaagtcaa acaggttaca tttgattcag caaatcaacg catgattatt
    34081 ggcgatgatg tcaaaattta cactgtaaac ggtaatcaaa tcgtcgtaga tgatatggat
    34141 agagacccat cggaccaaat cgttttaact aaataagact atgcaagtag aaagggctgg
    34201 atttttcagc ctttttactt ttacctagaa aataatcata aatacttgcc ttctaccgaa
    34261 tacctgcgtt atactagtat caattacttg tttttagcat tcaaactatc aaggagggga
    34321 tatgaaatat aggaaattcc agttattgat gtccaagtat ggctttagtc tttcgattat
    34381 gctacttgaa ctttgtcttg tttttggtct ctttctttat ttaggacgca tggctcccat
    34441 tttatggatt actgtcctca ttctactgag tatcatcaca atcatttcga tagtcaaccg
    34501 taatacgact cctgagaata aggtaacctg gttgttagta gcctttgtac cagtatttgg
    34561 tcccttgctc tatctgatgt ttggtgaaag gcgattgtcc aaaaaagaaa tcaaacaact
    34621 gaagaagcta ggctctatgc atttccaaga agcaaatagc cagctactaa aagagaaatt
    34681 aaaagaaagt gacaaggcag cctatggagt catcaagtcc ttattgagta tggataccaa
    34741 tgctgacatc tatgatcaaa ctgcctctac attttttcct aacggagaag ctatgtggaa
    34801 aaagatggta gaagatctta aaaaggctga gaaatttatt ttcttggaat attacattat
    34861 agaagaaggt ttgatgtgga atcgcatact agatatacta gagcaaaagg tagctcaggg
    34921 tgtagaggtt aagatgctct atgatgatat cggctgtatg gctactttaa caggagatta
    34981 tgcacatcga cttcgtcagc tgggcatcga ggcccataaa ttcaataaag ttattcctcg
    35041 tttgacagtg gcttataata acagagatca tagaaaaata ttgattgttg atggtcagat
    35101 agcctatact ggtggggtca atctggcaga tgagtacatt aaccacgtcg agagatttgg
    35161 ttattggaag gatagtggaa ttcgcttaga cggactagca gtaaaagctc tgacacgctt
    35221 atttttgacc acttggtaca ttaatcgagg agaaattagt gattttgatc aatatcattt
    35281 agaaaatcat tctatcccga gtgacggttt aaccattcca tacggaagtg gacccaagcc
    35341 aatttttcga gcgcaggtag ggaaaaaagt ttatcagagt ttaatcaatc aagcaacaga
    35401 atcggtctat attacgacac cttatttgat tatagattat gatttaacag agacaatcaa
    35461 aaatgcagct atgagagggg tcgatgttcg aattatcacc ccttacatac cagataagaa
    35521 gttcattcag ttagtcacga gaggagctta tcccgacctt ctttctgctg gtgttcggat
    35581 ttatgagtat agtccaggtt ttattcatag taagcagatg ttggtagacg aagattttgc
    35641 ggtggtgggg acaatcaatc tcgactaccg gagcttggta caccattatg aaaatgcagt
    35701 cttactctat aaaactcctt ctataaggga aatcgcccga gattttcgaa atatatttgc
    35761 agattctcag gaagtctatc ctcattctat caaaacgagc tggtatcaaa agcttgtaaa
    35821 agaaatcgcc cagctattcg cccctatctt ataagaaatc tagaacttag gatacaaacc
    35881 agacctattt ttcttgtctt ttacgaatag aaagaaagag gaggggaatt catgctaact
    35941 aaggaagaag tgaatgatat gattgagttc aaacagacac atttacaccg ctttcgggaa
    36001 attgaaacct ttgtgaaact atgcaaaaaa tcactcaaac agccatcgca agctgacaat
    36061 cctaggactt tttgatatac taagacagat aaattgaaca ggagaaacga tatgagtgtg
    36121 tatggtagag tagaagaagt tcataaggag aatcgtgaac ctctagaata ccaaatcgaa
    36181 caagaatcgc atcatcgtga atcaagtcgt cttcctttgg tgaaaatttt actatggagt
    36241 acgcttgtaa cggggataac tctaggagtg ccgctattac tcgacttaat gagtgcacaa
    36301 gaagtgcagg atttttatgc aggttgggcg cttcatcaga cagggaagat ttacagcgac
    36361 tattatggaa gtcaaggttt gctttattat ttgctgactt acgtgagtca gggcggattt
    36421 ttctttgcca tctttgagtg gttagccttg gtagcaggag gatttttcct ttttagatca
    36481 gcggacacct tgacagagca aggagaccaa gctggacatc tggtgactat tttttacatg
    36541 ctagttacag gtcttgcttt tggtggaggc tatgcgactc ttttagcgct tcctttctta
    36601 ttcgcagcct ttagtttagt tgcggcttac ctaagcaatc caagccatga taagggattt
    36661 gtacggattg ggctagcttt ggcaggcgga tttttctttg ctcccttatc atcgctcctg
    36721 tttattgctg tagtgagttt aggcttgttg gtctttaacc ttgggcatag acgttttgtg
    36781 catgggtttt atcagtttct tgcagtggct ttaggttttt cacttgtctt ttatccaact
    36841 gcctactata gtgctgcaac aggaagtttt ggggatgcga ttagtggtat tcgttatcct
    36901 attgacagta ttcgctttga ttttacttct aaaattttag agaatatgtt tttttatggc
    36961 ttgttgtccc ttggtttggg atttgtggtt tgtatctttt taggtctctt tcaatccaaa
    37021 ccctttaaac tatacgtcat ttcggttcct gcaagtcttg tggtaatttt aggtttgatt
    37081 ttacttttct tttcacaaga gcctctgcac gcttcttatt tgatggtcgt cttccctgtt
    37141 ttcctacttt tattggtaac caatattaag agtcaacaga gggggcgtag tgctagaaga
    37201 agccgaagag aaacgccagt tagcctatgg agtcgtttct tcaaaggaaa tctatatctg
    37261 ctagtttttg ggtttgtcta tcttttgtct gttccttttt tgatgaagtt tgtcctttat
    37321 ccagtacctt atcaagaacg taatcgtctt gctgatttgg taaaagagga gacaaatacg
    37381 gaagatgcta tctatgcatg ggatgatact gcgactcttt atcgtaagag tgagcgcttg
    37441 tcgccatcgg cgattttgtc cccgttgcac tatacagcaa ctgaggaaaa tcgtaataag
    37501 ttacttaatg acttgaaaga aaaacaacct aaggtgattg tggtaaatga caaggtggta
    37561 gtctggtctg aagtggaaac actcttaaaa gaaaattacc aacaagtaaa gactgattac
    37621 tcagagttta aagtctataa aattaaataa ccaaatcaat atcttgtgta tttttaaaaa
    37681 ttttaggatt tttaacacaa gatattgatt tttcttttta gagtggtata atacttttta
    37741 gaaagaacat tttagaaaag agcatgcgta tgattgcact agaagaaaaa attacaattt
    37801 tgccaactct cttcgtcgag aaacgagatg ggagacgtgt tgtatttgat gtggacaaga
    37861 ttgacaaggc tctccacaag gcggctgaca aggttatgga tgtgacaccc ctggttgaaa
    37921 aacgcctcaa tgatctgact gagcgaatta ttacagaaat tcatagtcgc tttccacagg
    37981 gaattaagat ttacgaaatt caaaatatcg tagaacatga actccttgaa gccaaagaat
    38041 atgcgctggc tgaggagtat attacttatc ggacacagag ggattttgag cgctcaaaag
    38101 cgacggatat caactttagt attcataaac ttctcaacaa agaccagaca gttgtcaatg
    38161 aaaatgctaa taaagacagt gatgtcttta acactcagcg tgatttgaca gcagggattg
    38221 ttgggaaatc aatcggactg caaatgcttc ctaagcacgt agccaatgcc caccaaaagg
    38281 gggatatcca ctatcacgat ttggactaca gtccctatac ccctatgacc aactgctgtt
    38341 tggttgattt taagggtatg ttggaaaatg gttttaagat tggaaatgca gaggtagaga
    38401 gtcccaagtc tatccagact gcgacagcac agatttctca aatcattgcc aacgttgctt
    38461 ctagccagta cggtggctgt tcagctgacc gtatcgatga aattttggcg ccttatgcag
    38521 agaagaacta tcaaaaacat ctcaaagatg cagaagagtg ggtattgcct gaaaaacggg
    38581 aagattacgc ttggaagaaa acgcaaaagg acatctacga tgccatgcaa tctcttgagt
    38641 atgaaatcaa tactctcttc acttcaaatg gacaaacacc ttttacttcg ttaggttttg
    38701 gtctgggaac cagtcgtttt gaacgagaaa ttcaaaaagc tattttaaac attcgcatca
    38761 agggtcttgg ttcagaacac cgtacggcta tctttcctaa acttattttc actctgaaaa
    38821 gaggccttaa tttagaggaa ggaactccca actacgacat caagcagttg gctcttgagt
    38881 gtgcaaccaa acggatgtat ccagatgttt tatcttacga taagattgtt gacttgacag
    38941 gatccttcaa ggtgcctatg ggttgccgtt ctttcctcca aggatggaag gatgaaaatg
    39001 gtgtagaagt caattcaggt cgcatgaatc tgggtgttgt gacggttaat ctgcctcgta
    39061 ttgctcttga gtctgaaggt gatatgaata agttctggga aatcttcaac gagcgaatga
    39121 atatcgcaga agatgctctt gtttaccgtg tcgaacgcac taaagaggcg acaccagcaa
    39181 atgctcctat tctttatcag tacggtgctt ttggccatcg tctaggtaaa gaagaaagtg
    39241 ttgaccagct ctttaagaat cgtcgtgcga ccgtttcgct gggctatatc ggcttgtatg
    39301 aagtagcgac agttttcttt ggtaacagct gggaaagtaa tccagatgct aaggaattca
    39361 cgctagacat cattcacgat atgaaacgcc gtgtagaaga gtggtcagac caatatggct
    39421 accatttctc tatctactca acaccatccg aaagtctgac agaccgtttc tgccgactag
    39481 atatagacaa gtttggctct attcctgata tcacagacaa ggaatactac accaactctt
    39541 tccactacga tgttcgtaaa aatccaacac cgtttgaaaa attggacttt gagaaagtct
    39601 atccagaagc aggtgcgtca ggtggtttca tccattattg tgagtatcca gtccttcagc
    39661 aaaatccaaa ggccttggaa gctgtctggg attatgctta tgaccgtgta ggctatctag
    39721 gcaccaatac tccgattgac cgttgctaca agtgtgactt tgaaggggat tttgaaccaa
    39781 ctgagagagg gtttgcttgt ccaaactgtg gcaatagcga tcctaaaaca gtagacgttg
    39841 ttaaacggac ttgtggctat cttggcaatc ctcaagcaag accgatggtc aacgggcgtc
    39901 acaaggaaat cgctgcgcgt gtcaaacata tgaatggttc aacgattaaa atagctgggc
    39961 atcaagtaac aaattagaaa gaaatgaaat ggggaaatat caactagacg ataaggggcg
    40021 cgcacaagtg acccgttatc acgagaaata ctctaaaggt ggagctggta agaaagaacg
    40081 cttgcttagc ttcagagaac aatttttaaa caagaacaag aaaaaataaa agtgagagcc
    40141 agctctcgct tttctcatag tgggaggtaa ggatggaatt acgcagacca agattagcgg
    40201 ataagaaagc tgttttagat atgatgacag agtttgaaaa gagccaatca gcccatgatg
    40261 gaggattttg ggatacagag aactttgtgt atgaagagtg gttggaaagc aatcaggaac
    40321 aggaaatggg gattaatctg cctgaaggat gggttcctgc aattcagtta gtggcttttt
    40381 ctgagaaagg tcaagcagtt ggatttctta atctccggtt gcgcctcagt aactttctac
    40441 tagaagaagg tgggcacatt ggctactcca tccgtccatc tgaaagaggc aagggttatg
    40501 caaaagagac tctccgtcag ggcttgcaag ttgctaagga aaagaacatc aagaaagctc
    40561 tggtgacctg tagcgtgaat aatcctgcta gcagagcagt cattctagca aatggtggaa
    40621 tatttgagga tgctcacaat ggagtcgagc gttattggat agaggtagcg aatgaataat
    40681 ccaaaaccac aagaatggaa aagcgaggaa cttagtcaag gtcgtatcat tgactacaag
    40741 gcctttaact ttgtggacgg cgaaggcgtg cgcaactctc tctatgtatc aggctgtatg
    40801 tttcactgcg agggatgtta taatgttgcg acttggtctt ttaatgctgg cattccctat
    40861 acagcagaat tagaagagca gatcatggca gaccttgccc aaccctatgt tcaaggcttg
    40921 actttgctgg gaggggaacc ttttctcaat actggcattc tcttgcctct agttaaacgc
    40981 atccgaaagg aattgtcaga caaggacatt tggtcctgga cgggctacac ttgggaagaa
    41041 atgatgttgg aaactccaga taaactggaa ctcttatcat tgattgacat tcttgtcgat
    41101 ggacgatacg atcgaactaa gagaaatctc atgctccagt ttcgaggttc gtccaaccaa
    41161 cgaattatcg atgtgcaaaa atcgctcaaa agtgggcaag tagtgatttg ggacaagctc
    41221 aatgacggaa aagaaagcta tgaacaggtg aagagagaat gaagaaaaaa gacttagtag
    41281 accaactagt ctcagagatc gagacgggga aagtcaggac actgggaata tacggtcatg
    41341 gagcttcagg taaatcaacc tctgcacagg aattgtacca agctttagat tctactacag
    41401 taaatttgct agaaacagat ccctatatca cctcaggacg ccatctggta gtacccaagg
    41461 acgcgccgaa tcaaaaggtg acagccggtc tgccagtggc gcatgaactg gagagtttgc
    41521 agagagatat ccttgccttg caggcgagta tggatgtctt gacaattgaa gaaccttgga
    41581 aggctagtga ggtcttgtct ggagccaaac caattttgat tgtcgaaggg atgtctgttg
    41641 gctttcgacc caaggaactc tttgaaaaaa ccatctgttt ctacacggat gaggagaccg
    41701 aattaaagcg acgccttgct agagatacga ctgtgagaaa tcgtgatgca tcctttatat
    41761 tggctagcca tcagatgaga cgggagcagt atctgcgata ctataaagaa actgagtcta
    41821 aggcggatat cttagtggat caatcagaag ataaatttga tgtcaagagg acttaactta
    41881 tgtatagaag aaatatagaa gaaaatccct aattttagaa agaaaaagta ggaaaacagt
    41941 ttcatcccaa aaaaacgaaa aaacctaaca aatcccttgc aatcgcaggg gatttgtgtt
    42001 attctattat ggtgctgtaa attacagcct tagttttgat gcaagaggtt gcgacacgct
    42061 cggttgcatt gccacgcaac accgtgtcgg ttttcttgtg gagctagcct attatcttaa
    42121 atagacgaaa aggagaaaaa gatggcaaac aaaaaaatcc gtatccgttt gaaagcttac
    42181 gaacaccgta cgcttgacac agcggctgca aaaatcgtag aatcagctac tcgtacaggt
    42241 gcacaagttg cgggtccaat cccacttcca actgaacgta gcctctacac aatcattcgt
    42301 gcgactcaca aatacaaaga ctctcgcgaa caatttgaaa tgcgtacaca caaacgtttg
    42361 atcgatatcg ttaacccaac tcaaaaaaca gttgatgcct tgatgaaatt ggatcttcca
    42421 agtggtgtaa acgtagaaat caaactttaa tctaaaatat aaaagagcag aggctggtgt
    42481 ttcaatctaa ttgaacacgg gctaaactcg gtgtgaaaaa gataaacttc ctagtgtctg
    42541 ctagacactg cgtcagtttc ctattttcaa gttgagtttg acgccctttg tatcttagac
    42601 ttgagcataa aaaacgctcg ttaaaaactt tttgaataaa aaatatagaa aaggaactat
    42661 tttctcatga caaaaggaat cttagggaaa aaagtgggaa tgactcaaat cttcactgaa
    42721 gctggcgaat tgatccctgt aacagttatt gaagcaactc caaacgttgt tcttcaagtt
    42781 aaaactgttg aaacagacgg atacaacgct atccaagttg gtttcgatga caaacgcgaa
    42841 gtattgagca acaaacctgc taaaggacat gtagcgaaag ctaacacggc tcctaagcgc
    42901 ttcattcgtg aattcaaaaa cgttgaaggc ttggaagttg gtgctgaaat tacagttgaa
    42961 acattcgcag ctggagacgt tgttgacgta actggtactt ctaaaggtaa aggtttccaa
    43021 ggtgttatca aacgccacgg acaatcacgt ggaccaatgg ctcacggttc tcgttaccac
    43081 cgtcgtccag gttctatggg acctgttgca cctaaccgcg tattcaaagg taaaaacctt
    43141 gcagggcgta tgggtggcga ccgcgtaaca attcaaaacc ttgaagttgt acaagttgtt
    43201 ccagaaaaga acgttatcct tatcaaaggt aacgtaccag gtgctaagaa atctcttatc
    43261 actatcaaat cagcagttaa agctggtaaa taataaagaa aggggaaatc agtcacaatg
    43321 gcaaacgtaa cattatttga ccaaactggt aaagaagctg gccaagttgt tcttagcgat
    43381 gcagtatttg gtatcgaacc aaatgaatca gttgtgtttg atgtaatcat cagccaacgc
    43441 gcaagccttc gtcaaggaac acacgctgtt aaaaaccgct ctgcagtatc aggtggtgga
    43501 cgcaaaccat ggcgtcaaaa aggaactgga cgtgctcgtc aaggttctat ccgctcacca
    43561 caatggcgtg gtggtggtgt tgtcttcgga ccaactccac gttcatacgg ctacaaactt
    43621 ccacaaaaag ttcgtcgcct agctcttaaa tcagtttact ctgaaaaagt tgctgaaaac
    43681 aaattcgtag ctgtagacgc tctttcattt acagctccaa aaactgctga atttgcaaaa
    43741 gttcttgcag cattgagcat cgattctaaa gttcttgtta tccttgaaga aggaaatgaa
    43801 ttcgcagctc tttcagctcg taaccttcca aacgtgaaag ttgcaactgc tacaactgca
    43861 agtgttcttg acatcgcaaa tagcgacaaa cttcttgtca cacaagcagc tatctctaaa
    43921 atcgaggagg ttcttgcata atgaatttgt atgatgttat caaaaaacct gtcatcactg
    43981 aaagctcaat ggctcaactt gaagcaggga aatatgtatt tgaagttgac actcgtgcac
    44041 acaaactttt gatcaagcaa gctgttgaag ctgctttcga aggtgttaaa gttgccaatg
    44101 ttaacacaat caacgtaaaa ccaaaagcta aacgtgttgg acgttacact ggttttacta
    44161 acaaaactaa aaaagctatc atcacactta cagctgattc taaagcaatc gagttgtttg
    44221 ctgctgaagc tgaataatct aaggaggaaa tatcgtggga attcgtgttt ataaaccaac
    44281 aacaaacggt cgccgtaata tgacttcttt ggatttcgct gaaatcacaa caagcactcc
    44341 tgaaaaatca ttgcttgttg cattgaagag caaggctggt cgtaacaaca acggtcgtat
    44401 cacagttcgt caccaaggtg gtggacacaa acgtttctac cgtttggttg acttcaaacg
    44461 taataaagac aacgttgaag cagttgttaa aacaatcgag tacgatccaa accgttctgc
    44521 aaacatcgct cttgtacact acactgacgg tgtgaaagca tacatcatcg ctccaaaagg
    44581 tcttgaagta ggtcaacgta tcgtttcagg tccagaagca gatatcaaag tcggaaacgc
    44641 tcttccactt gctaacatcc cagttggtac tttgattcac aacatcgagt tgaaaccagg
    44701 tcgtggtggt gaattggtac gtgctgctgg tgcatctgct caagtattgg gttctgaagg
    44761 taaatatgtt cttgttcgtc ttcaatcagg tgaagttcgt atgattcttg gaacttgccg
    44821 tgctacagtt ggtgttgtcg gaaacgaaca acatggactt gtaaaccttg gtaaagcagg
    44881 acgtagccgt tggaaaggta tccgcccaac agttcgtggt tctgtaatga accctaacga
    44941 tcacccacac ggtggtggtg aaggtaaagc accagttggt cgtaaagcac catctactcc
    45001 atggggcaaa cctgctcttg gtcttaaaac tcgtaacaag aaagcgaaat ctgacaaact
    45061 tatcgttcgt cgtcgcaacg agaaataata ttaaactagt cgcttaagca actagtaaat
    45121 ccgccagctc ggtagcgctc cataggagtg caagccgctg tggtacaaca tttaaaggag
    45181 aaaatataaa aatgggacgc agtcttaaaa aaggaccttt cgtcgatgag catttgatga
    45241 aaaaagttga agctcaagct aacgacgaaa agaaaaaagt tattaaaact tggtcacgtc
    45301 gatcaacgat cttcccaagt ttcattggtt acactattgc agtttatgac ggacgtaaac
    45361 acgtacctgt ttacatccaa gaagacatgg taggccacaa acttggtgaa tttgcaccaa
    45421 ctcgtactta caaaggtcac gctgcagacg acaagaaaac acgtagaaaa taaggagaac
    45481 ataaatggca gaaattactt cagctaaagc aatggctcgt acagtacgtg tttcacctcg
    45541 taaatcacgt cttgttcttg ataacatccg tggtaaaagc gtagccgatg caatcgcaat
    45601 cttgacattc actccaaaca aagctgctga aatcatcttg aaagttttga actcagctgt
    45661 agctaacgct gaaaacaact ttggtttgga taaagctaac ttggtagtat ctgaagcatt
    45721 cgcaaacgaa ggaccaacta tgaaacgttt ccgtccacgt gcgaaaggtt cagcttcacc
    45781 aatcaacaaa cgtacagctc acatcactgt agctgttgca gaaaaataag gaggtaaaat
    45841 cgtgggtcaa aaagtacatc caattggtat gcgtgtcggc atcatccgtg attgggatgc
    45901 caaatggtat gctgaaaaag aatacgcgga ttaccttcat gaagatcttg caatccgtaa
    45961 attcgttcaa aaagaacttg ctgacgcagc agtttcaact attgaaatcg aacgcgcagt
    46021 aaacaaagtt aacgtttcac ttcacactgc taaaccaggt atggttatcg gtaaaggtgg
    46081 tgctaacgtt gatgcactcc gtgcaaaact taacaaattg actggaaaac aagtacacat
    46141 caacatcatc gaaatcaaac aacctgattt ggatgctcac cttgtaggtg aaggaattgc
    46201 tcgtcaattg gagcaacgtg ttgctttccg tcgtgcacaa aaacaagcaa tccaacgtgc
    46261 aatgcgtgct ggagctaaag gaatcaaaac tcaagtatca ggtcgtttga acggtgcaga
    46321 tatcgcccgt gctgaaggat actctgaagg aactgttccg cttcacacac ttcgtgcaga
    46381 tatcgattac gcttgggaag aagcagatac tacatacggt aaacttggtg ttaaagtatg
    46441 gatctaccgt ggtgaagttc ttccagctcg taaaaacact aaaggaggta aataaccaat
    46501 gttagtacct aaacgtgtta aacaccgtcg tgagttccgt ggaaaaatgc gcggtgaagc
    46561 aaaaggtgga aaagaagtag cattcggtga atacggtctt caagctacaa ctagccactg
    46621 gatcactaac cgccaaatcg aagctgctcg tatcgccatg actcgttaca tgaaacgtgg
    46681 tggtaaagtt tggattaaaa tcttcccaca caaatcatac actgctaaag ctatcggtgt
    46741 gcgtatggga tctggtaaag gggcacctga aggttgggta gcaccagtta aacgtggtaa
    46801 agtgatgttc gaaatcgctg gtgtatctga agagattgca cgtgaagcgc ttcgacttgc
    46861 tagccacaaa ttgccagtta aatgtaaatt cgtaaaacgt gaagcagaat aaggagaagg
    46921 catgaaactt aatgaagtaa aagaatttgt taaagaactt cgtggtcttt ctcaagaaga
    46981 actcgcgaag cgcgaaaacg aattgaaaaa agaattgttt gaacttcgtt tccaagctgc
    47041 tactggtcaa ttggaacaaa cagctcgctt gaaagaagtt aaaaaacaaa tcgctcgtat
    47101 caaaacagtt caatctgaag cgaaataata gactagggaa ggagaaattt caatggaacg
    47161 caataatcgt aaagttcttg ttggacgtgt tgtatctgac aaaatggaca agacaatcac
    47221 agttgtagtt gaaacaaaac gtaaccaccc agtctatggt aaacgtatta actactctaa
    47281 aaaatacaaa gctcatgatg aaaacaatgt tgccaaagaa ggcgatatcg tacgtatcat
    47341 ggaaactcgc ccgctttcag ctacaaaacg tttccgtctt gtagaagttg ttgaagaagc
    47401 ggtcatcatc taatcaaacc tgaaaggaga aaactgaaat gattcaaaca gaaactcgtt
    47461 tgaaagtcgc agacaacagc ggtgctcgcg aaatcttgac tatcaaagtt cttggtggtt
    47521 caggacgtaa atttgcaaac atcggtgatg ttatcgtggc atctgtaaaa caagctactc
    47581 ctggtggtgc ggttaaaaaa ggtgacgttg ttaaagcagt tatcgttcgt actaaatcag
    47641 gtgctcgtcg tgctgatggt tcatacatca aatttgacga aaacgcagca gttatcatcc
    47701 gtgaagacaa aactcctcgc ggaacacgta tctttggccc agttgcacgt gaattgcgtg
    47761 aaggtggctt catgaagatc gtgtcacttg ctccagaagt actttaattt ttaggaacaa
    47821 actagtcccc tagcttcaag ctagggtgcc cttatgggcg taagaaaaat caaggagaaa
    47881 cctaatgttt gtaaaaaaag gcgacaaagt tcgcgtaatc gctggtaaag ataagggaac
    47941 agaagctgtt gtccttactg cccttccaaa agtaaacaaa gttatcgttg aaggtgttaa
    48001 cattgttaag aaacaccaac gtccaactaa cgagcttcct caaggtggta tcatcgagaa
    48061 agaagcagct atccacgtat caaacgttca agttttggac aaaaatggtg tagctggtcg
    48121 tgttggttac aaatttgtag acggtaaaaa agttcgctac aacaaaaaat caggcgaagt
    48181 gcttgattaa tcacgaagga aaggagaagt ataatggcaa atcgtttaaa agaaaaatat
    48241 cttaatgaag tagttcctgc tttgacagaa caattcaact actcatcagt gatggctgtg
    48301 cctaaagtag ataagattgt tttgaacatg ggtgttggtg aagctgtatc aaacgctaaa
    48361 agccttgaaa aagctgctga agaattggca cttatctcag gtcaaaaacc acttatcact
    48421 aaagctaaaa aatcaatcgc cggcttccgt cttcgtgaag gtgttgcgat cggtgcaaaa
    48481 gttacccttc gtggtgaacg tatgtacgaa ttcttggata aattggtatc agtttcactt
    48541 ccacgtgtac gtgacttcca cggtgtccca acaaaatcat ttgatggacg cgggaactac
    48601 acacttggtg tgaaagaaca attaatcttc ccagaaatca acttcgatga cgttgacaaa
    48661 actcgtggtc ttgacatcgt tatcgtaaca actgctaaca ctgacgaaga gtcacgtgca
    48721 ttgcttacag gccttggaat gccttttgca aaataatata ggaggtaaat ctaatggcta
    48781 aaaaatcaat ggtagctaga gaggctaaac gccaaaaaat tgttgaccgt tatgctgaaa
    48841 aacgtgctgc attaaaggcg gcaggggact acgaaggttt atctaaatta cctcgcaacg
    48901 cttcaccgac tcgtttacat aatcgttgta gagttacggg gcgcccacat tcagtttacc
    48961 gcaaatttgg tctgagtcgt atcgcttttc gcgaacttgc gcataaaggt caaattcctg
    49021 gtgtaacaaa agcatcttgg taatttaaga tatcaagggc gtcaaaactc caagtaaaaa
    49081 taggaaactt gacgaagaaa ctaaagtttc taggaaagtt tatctttttc acacagagtt
    49141 tagcccgggt tcaattgggc ttgccaattt gaacacgagc tacagctttg gcaaaaaaga
    49201 ccaatttgct ttggagcatt gcttctgcat taaattgtct atttttgctc gtgctgttac
    49261 gctctttgta tcatgtatta actagcaagt gcaacttgca aactactagt aagaggagaa
    49321 aaacaaaatg gttatgactg acccaatcgc agacttccta actcgtattc gtaatgctaa
    49381 ccaagctaaa cacgaagtac ttgaagtacc tgcatcaaac atcaaaaaag ggattgctga
    49441 aatccttaaa cgcgaaggtt ttgtaaaaaa cgttgaaatc atcgaagatg acaaacaagg
    49501 cgtcatccgt gtatttctta aatacggacc aaatggtgaa aaagttatca ctaacttgaa
    49561 acgtgtttct aaaccaggac ttcgtgtcta caaaaaacgt gaagaccttc caaaagttct
    49621 taacggactt ggaattgcca tcctttcaac ttctgaaggt ttgcttactg ataaagaagc
    49681 acgccaaaag aatgttggtg gtgaggttat cgcttacgtt tggtaaaatc aagatacaaa
    49741 gctcgtaaag aacaaagcaa aattaggaag ttggagaagt ttgtttacaa acaagccaac
    49801 ttatctattt tgcacagttc ttagagcgtg ttcagttcag ctcttgaact aaataagtat
    49861 ctgaaccccg tgaaaactgg ccgttttggc ctgacaattt aacaggagaa aataaacatg
    49921 tcacgtattg gtaataaagt tatcgtgttg cctgctggtg ttgaactcgc taacaatgac
    49981 aacgttgtaa ctgtaaaagg acctaaagga gaacttactc gtgagttctc aaaagatatt
    50041 gaaatccgtg tggaaggtac tgaagtaact cttcaccgtc caaacgattc aaaagaaatg
    50101 aaaactatcc acggaactac tcgtgccctt ttgaacaaca tggttgttgg tgtatcagaa
    50161 ggattcaaga aagaacttga aatgcgtggg gttggttacc gtgcacagct tcaaggatca
    50221 aaacttgttt tggctgttgg taaatctcat ccagacgaag ttgaagctcc agaaggaatt
    50281 acttttgaac ttccaaaccc aacaacaatc gttgttagcg gaatttcaaa agaagtagtt
    50341 ggtcaaacag ctgcttacgt acgtagcctt cgttcaccag aaccatataa aggtaaaggt
    50401 atccgttacg ttggtgaatt cgttcgccgt aaagaaggta aaacaggtaa ataatgttga
    50461 gtggttgatc atcaaccacc aacctatttt ccaactttgt gcatagcaca cgatttaaaa
    50521 ctaaagaggt gaaaactgtg atttcaaaac cagataaaaa caaactccgc caaaaacgcc
    50581 accgtcgcgt tcgcggaaaa ctctctggaa ctgctgatcg cccacgtttg aacgtattcc
    50641 gttctaatac aggcatctac gctcaagtga ttgatgacgt agcgggtgta acgctcgcaa
    50701 gtgcttcaac tcttgataaa gaagtttcaa aaggaactaa aactgaacaa gccgttgctg
    50761 tcggtaaact cgttgcagaa cgtgcaaacg ctaaaggtat ttcagaagtg gtgttcgacc
    50821 gcggtggata tctatatcac ggacgtgtga aagctttggc tgatgcagct cgtgaaaacg
    50881 gattgaaatt ctaataggag gacactagaa aatggcattt aaagacaatg cagttgaatt
    50941 agaagaacgc gtagttgctg tcaaccgtgt tacaaaagtt gttaaaggtg gacgtcgtct
    51001 tcgtttcgca gctcttgttg ttgttggtga ccacaatggt cgcgtaggat ttggtactgg
    51061 taaagctcaa gaagttccag aagcaatccg taaagcagta gatgatgcta agaaaaactt
    51121 gatcgaagtt cctatggttg gaacaacaat cccacacgaa gttctttcag aattcggtgg
    51181 agctaaagta ttgttgaaac ctgctgtaga aggttctgga gttgccgctg gtggtgcagt
    51241 tcgtgccgtt gtggaattgg caggtgtggc agatattaca tctaaatcac ttggttctaa
    51301 cactccaatc aacattgttc gtgcaactgt tgaaggtttg aaacaattga aacgcgctga
    51361 agaaattgct gcccttcgtg gtatttcagt ttctgatttg gcataagaaa ggggataaaa
    51421 tggctcaaat taaaattact ttgactaagt ctccaatcgg acgcattcca tcacaacgta
    51481 aaactgttgt agcacttgga cttggcaaat tgaacagctc tgttattaaa gaagataacg
    51541 ctgctatccg tggtatgatt acagcagtat ctcacttagt aacagttgaa gaagtaaact
    51601 aatgaagttt taggggatgt gcactgtacc atcccctaaa actagatata gtcatctatg
    51661 atgacatcgt ataggcgagt tgatggggga gacaaccttt tctcccttat cggcgctagc
    51721 attttacaaa agaggagaaa ataaaaatga aacttcatga attgaaacct gcagaaggtt
    51781 ctcgtaaagt acgtaaccgc gttggtcgtg gtacttcatc aggtaacggt aaaacatctg
    51841 gtcgtggtca aaaaggtcaa aaagctcgta gcggtggcgg agttcgcctt ggttttgaag
    51901 gtggacaaac tccattgttc cgtcgtcttc caaaacgtgg attcactaac atcaacgcta
    51961 aagaatacgc aattgtgaac cttgaccaat tgaacgtctt tgaagatggt gctgaagtaa
    52021 ctccagttgt tcttatcgaa gcaggaattg ttaaagctga aaagtcaggt attaaaattc
    52081 ttggtaacgg tgagttgact aagaaattga ctgtgaaagc agctaaattc tctaaatcag
    52141 ctgaagaagc tatcactgct aaaggtggtt cagtagaagt catctaagag aggtgaccta
    52201 tgttttttaa attattaaga gaagctctta aagtcaagca ggttcgatca aaaattttat
    52261 ttacaatttt tatcgttttg gtctttcgta tcggaactag cattacagtt cctggtgtga
    52321 atgccaatag cttgaatgct ttaagtggat tatccttctt aaacatgttg agcttggtgt
    52381 cggggaatgc cctaaaaaac ttttcgattt ttgccctagg agttagtccc tatatcaccg
    52441 cttctattgt tgtccaactc ttgcaaatgg atattttacc caagtttgta gagtggggta
    52501 aacaagggga agtaggtcga agaaaattga atcaagctac tcgttatatt gctctagttc
    52561 tcgcttttgt gcaatctatc gggattacag ctggttttaa taccttggct ggagctcaat
    52621 tgattaaaac tgctttaact ccacaagttt ttctgacgat tggtatcatc ttaacagctg
    52681 gtagtatgat tgtcacttgg ttgggtgagc aaattacaga taagggatac ggaaacggtg
    52741 tttccatgat tatctttgcc gggattgttt cctcaattcc agagatgatt cagggcatct
    52801 atgtggacta ctttgtgaac gtcccaagta gccgtatcac ttcatctatc attttcgtaa
    52861 tcattttgat tattactgta ttgttgatta tttactttac aacttatgtt caacaagcag
    52921 aatacaaaat tccaatccaa tatactaagg ttgcacaagg tgctccatct agctcttacc
    52981 ttccgttaaa ggtaaaccct gctggagtta tccctgttat ctttgccagt tcgattactg
    53041 cagcgcctgc ggctattctt cagtttttga gtgccacagg tcatgattgg gcttgggtaa
    53101 gggtagcaca agagatgttg gcaactactt ctccaactgg tattgccatg tatgctttgt
    53161 tgattattct ctttacattc ttctatacgt ttgtacagat taatcctgaa aaagcagcag
    53221 agagcctaca aaagagtggt gcctatatcc atggagttcg tcctggtaaa ggtacagaag
    53281 aatatatgtc taaacttctt cgtcgtcttg caactgttgg ttccctcttt cttggtgtga
    53341 tttccatttt accgattgca gctaaagatg tatttggtct ttctgatgtt gttgcctttg
    53401 gtggaacaag tctcttgatc attatctcta caggtatcga aggaatcaag caattggaag
    53461 gttacctatt gaaacgtaag tatgttggtt tcatggacag aacagaataa aagtatttac
    53521 tgaatcagta aatactgagg gagtggaggt ttaaactctg acatttgtaa gagttggatc
    53581 tcccctcttc tattttgttt ttaaataggg gtgaaaagac tttttgcttc tatttaaaaa
    53641 taaaataagg agatcaaatc atgaatcttt tgattatggg cttacctggt gcaggtaagg
    53701 gaactcaagc agcaaaaatc gtagaacaat tccatgttgc acatatctca acaggtgata
    53761 tgttccgcgc tgcaatggca aatcaaactg aaatgggtgt tcttgctaag tcatatattg
    53821 acaagggtga attggttcct gacgaagtta caaatggaat cgtaaaagaa cgcctttcac
    53881 aagatgatat taaagaaaca ggattcttat tggatggtta cccacgtaca attgaacaag
    53941 ctcatgcctt ggacaaaaca ttggctgaac ttggcattga actagaaggt attatcaata
    54001 ttgaagtgaa ccctgacagc ctcttggaac gtttgagtgg ccgtatcatc caccgcgtaa
    54061 ctggagaaac tttccacaag gtctttaacc caccagttga ctataaagaa gaagattact
    54121 accaacgtga agatgataag cctgagacag taaaacgtcg tttggatgtt aatattgctc
    54181 aaggagaacc aatcattgct cactaccgtg ccaaaggttt ggttcatgac atcgaaggta
    54241 atcaagatat caatgatgtc ttctcagata ttgaaaaagt attgacaaat ttgaaataaa
    54301 gcgtttttca cacttgcaaa aatccgctac aaatgttata ctgaaatagt ctgacttata
    54361 attgttgtct ctgtgtctag aggcatcgaa tcgaaattta tggaggtgct tttgcgtggc
    54421 aaaagacgat gtgattgaag ttgaaggcaa agtagttgat acaatgccga atgcaatgtt
    54481 tacggttgaa cttgaaaatg gacatcagat tttagcaaca gtttctggta aaattcgtaa
    54541 aaactatatt cgtattttag cgggagatcg tgttactgtc gaaatgagtc catatgactt
    54601 gacacgtgga cgtatcactt accgctttaa ataatcgaaa aacttggagg gataagaaat
    54661 gaaagtaaga ccatcggtca aaccaatttg cgaatactgt aaagttattc gtcgtaatgg
    54721 tcgtgttatg gtaatttgcc cagcaaatcc aaaacacaaa caacgtcaag gataagatag
    54781 aaaggagaaa acatggctcg tattgctgga gttgatattc caaatgacaa acgcgtagta
    54841 atctcattga cttatgttta tggtatcgga cttgcaacat ctaagaaaat tttggctgct
    54901 gctggaatct cagaagatgt tcgtgtacgt gatcttacat cagatcaaga agatgctatc
    54961 cgtcgtgaag tggatgcaat caaagttgaa ggtgaccttc gtcgtgaagt aaacttgaac
    55021 atcaaacgtt tgatggaaat cggttcatac cgtggtatcc gtcaccgtcg tggacttcct
    55081 gtccgtggac aaaatactaa aaacaacgct cgcactcgta aaggtaaagc tgttgcgatt
    55141 gctggtaaga aaaaataata taggaggtaa aagtcttggc taaaccaaca cgtaaacgtc
    55201 gtgtgaaaaa gaatatcgaa tctggtattg ctcatattca cgctacattt aataacacta
    55261 ttgttatgat tactgatgtg catggtaatg caattgcttg gtcatcagct ggtgctcttg
    55321 gtttcaaagg ttctcgtaaa tctacaccat tcgctgctca aatggcttct gaagctgctg
    55381 ctaaatctgc acaagaacac ggtcttaaat cagttgaagt tactgtaaaa ggtccaggtt
    55441 ctggtcgtga gtcagctatt cgtgcgcttg ctgccgctgg tcttgaagta acagcaattc
    55501 gtgatgtgac tccagtgcca cacaatggtg ctcgtcctcc aaaacgtcgc cgtgtataat
    55561 catcgcatta cactgctttt cgtttaagag ggagtaacta aatgatcgag tttgaaaaac
    55621 caaatataac aaaaattgat gaaaataaag attatggcaa gtttgtaatc gaaccacttg
    55681 aacgtggcta cggtacaact cttggtaact ctcttcgtcg tgtacttcta gcttctctac
    55741 caggagcagc tgtgacatct atcaacattg atggtgtgtt acatgagttt gacacagttc
    55801 caggtgttcg tgaagacgtg atgcaaatca ttctgaacat taaaggaatt gcagtgaaat
    55861 cgtacgttga agacgaaaaa atcatcgaac tggatgttga aggtcctgct gaagtaacag
    55921 ctggtgacat tttgacagat agcgatattg aaattgtaaa tccagatcat tatctcttta
    55981 caatcggtga aggttcttct ctaaaagcga ctatgactgt taacagtggt cgtggatatg
    56041 tacctgctga tgaaaataaa aaggataatg caccagttgg aacacttgct gtagattcta
    56101 tttatacacc agttacaaaa gtcaactatc aagtggaacc tgctcgtgta ggtagcaatg
    56161 atggtttcga caaattaacc cttgaaatct tgacaaatgg aacaattatt ccagaagatg
    56221 ctttagggct ttcagcacgt attttgacag aacatcttga tttgtttaca aatcttactg
    56281 agattgctaa gtcaactgaa gtgatgaaag aagctgatac tgaatctgac gaccgtattt
    56341 tagatcgtac gattgaggaa ctggacttgt ctgtgcgttc atacaactgt ttaaaacgtg
    56401 ccggtatcaa tactgtgcat gatttgacag aaaaatctga agcagagatg atgaaagtac
    56461 gaaatcttgg acgcaagagt ttggaagaag tgaaactcaa actcattgat ttgggtcttg
    56521 gattaaaaga taaataaagg aggaatacat ggcttaccgt aaactaggac gcactagctc
    56581 acaacgtaaa gcaatgcttc gcgatttgac aactgacctt ttgatcaacg aatcaatcgt
    56641 gacaactgaa gctcgtgcta aagaaatccg taaaactgtt gaaaaaatga ttactctagg
    56701 taaacgtggt gatttgcatg cacgtcgtca agcagctgct ttcgtacgta atgaaatcgc
    56761 atctgaaaac tatgatgaag caactgataa gtacacttct actacagcac ttcaaaaatt
    56821 gttctcagaa atcgcacctc gttatgctga acgtaacggt ggatacactc gtatccttaa
    56881 aactgaacca cgtcgtggtg atgcagcgcc aatggcgatc atcgaattag tataaaatca
    56941 tcaattttgt tgagtgttat gatgatggag tcttgtgctc ttagtctagc tctggtctac
    57001 cgctaggatt tcggtcctag cgggaacact catcataagt tgggatagta gacgcttgtt
    57061 tacgaaattg tttttttctt aagaacaact tcgtaagcag gcgtttttga gtattttcgt
    57121 tagaattatg ctatactatt tgaaaagaat cctgtttaat gttaaggttt cttattttaa
    57181 gaagaattgg agtttgctta tgaaagcgat tataactgtt gttggtaaag ataaatctgg
    57241 aattgttgca ggtgtttctg gtaaaattgc agaattagga ttgaatattg acgatatctc
    57301 tcaaactgtc ttggatgaat attttacgat gatggctatt gtatctagtg atgaaaagca
    57361 agattttacc tatcttcgta atgaatttga agcttttggg caaactttga atgtaaaaat
    57421 caatattcag agtgcagcga ttttcgaagc tatgtataat atctaggagg ttatcatgga
    57481 tattagacaa gttactgaaa ccatcgccat gattgaggag caaaatttcg atatcagaac
    57541 cattaccatg gggatttctc ttttggactg tatcgatcca gatatcaatc gtgctgcgga
    57601 gaaaatctat caaaaaatta cgacaaaggc ggctaattta gtagctgttg gtgatgaaat
    57661 tgcggctgag ttgggaattc ctatcgttaa taagcgtgta tcggtgacac ctatttctct
    57721 gattggggca gcgacagatg cgacggacta cgtggttctg gcaaaagcgc ttgataaggc
    57781 tgcgaaagag attggtgtgg actttattgg tggtttttct gccttagtac aaaaaggtta
    57841 tcaaaaggga gatgagattc tcatcaattc cattcctcgc gctttggctg agacggataa
    57901 ggtctgctcg tcagtcaata tcggctcaac caagtctggt attaatatga cggctgtggc
    57961 agatatggga cgaattatca aggaaacagc aaatctttca gatatgggag tggccaagtt
    58021 ggttgtattc gctaatgctg ttgaggacaa tccatttatg gcgggtgcct ttcatggtgt
    58081 tggggaagca gatgttatca tcaatgtcgg agtttctggt cctggtgttg tgaaacgtgc
    58141 tttggaaaaa gttcgtggac agagctttga tgtagtagcc gaaacagtta agaaaactgc
    58201 ctttaaaatc actcgtatcg gtcaattggt tggtcaaatg gccagtgaga gactgggtgt
    58261 ggagtttggt attgtggact tgagtttggc accaacccct gcggttggag actctgtggc
    58321 acgtgtcctt gaggaaatgg ggctagaaac agttggcacg catggaacga cggctgcctt
    58381 ggccctcttg aacgaccaag ttaaaaaggg tggagtgatg gcctgtaacc aggtcggtgg
    58441 tttatctggt gcctttatcc ctgtttctga ggatgaagga atgattgctg cagtgcaaaa
    58501 tggctctctt aatttagaaa aactagaagc tatgacggct atctgttctg ttggattgga
    58561 tatgattgcc atcccagaag atacgcctgc tgaaactatt gcggctatga ttgcggatga
    58621 agcagcaatc ggtgttatca acatgaaaac aacagctgtt cgtatcattc ccaaaggaaa
    58681 agaaggcgat atgattgagt ttggtggtct attaggaact gcacccgtta tgagggttaa
    58741 tggggcttcg tctgtcgact tcatctctcg cggtggacaa atcccagcac caattcatag
    58801 ttttaaaaat taagaaaata ggagaaattt taagttctat ttaagattag atgtgtatac
    58861 tataatcatt aaataaagac ctcctaatat tatttgaaac agataacact gaattagttt
    58921 gaatttgatt ttcatctaat atctttattt aatgaactcc taaacttttt cataataatc
    58981 tccttcaaaa gtcgcctgta tgggtggctt ttattttatc attcatgata taatagaagc
    59041 aaacggagga cggaaaatgg taaaagtacg attgtatttg gtacgtcatg gcaagaccat
    59101 gtttaacacg attggtcgcg cgcaaggttg gagcgatact cccttaactg ctgaaggtga
    59161 acgagggatt caagagttag gaatcggttt gcgagaatct gatctacagt ttgagcgcgc
    59221 ttattcgagt gattctggtc gtaccattca gaccatggga attatccttg aagaacttgg
    59281 cttgcagggg aaaatccctt atcgcatgga caagcgtatc agagaatggt gtttcggtag
    59341 ttttgatgga gcctatgatg gcgatctttt catgggcatt attcctcgta tctttaatgt
    59401 ggaccacgtt caccaattgt cttatgctga actggctgag ggcttggtag aggtcgatac
    59461 agctggttgg gctgaaggct gggaaaaact cagtggccga atcaaggaag gctttgaaat
    59521 gattgcaaaa gaaatggaag atcaaggtgg aggtaacgcc cttgttgtca gccatggaat
    59581 gactattgga accattgttt atctgattaa tggcatgcat ccgcatggtc tagataatgg
    59641 tagcgtgacg attcttgaat atgaggacgg tcagtttagg gttgaagttg tcggtgaccg
    59701 tagttaccga gagctaggac gtgagaagat ggaagaaggc tctatttaat cagtctagac
    59761 ttgcttgcca tgagctaggg atttgataag aatatcaaga taagaaaaaa cagccgaggg
    59821 tactcctttc ggctgttttt gatgtggaaa actaaagtgt aatgctattg cttttagaga
    59881 ttttcataaa caagagcaag gaacctactg ttagaacagt caggatagtt gacaaggctg
    59941 cggctacacc gtaatttcct ctgagaacct ctgtataaat agctacagtc attgttcttg
    60001 ttttgacatt gtagaggagg atagaagtag agagttttga aatcattgtg acccaagata
    60061 agatggctcc agaaatgata ccagatagca tcattggagt tgtaatctta gcaaaggtat
    60121 tgagacgact acttcctaag ctttcagcag cttcttcaat acttggtgct atttgttgta
    60181 agctagcaac agatgagcga atagtataag gtaatcttct gacagataga gacataatca
    60241 agatgaaagc agtccctgta atcataagaa atccacttcc aaatagacca gtattgaagg
    60301 aagaaatgaa ggcaatccct agaacggttc ctggtacaat ataaggtacc atactgaggc
    60361 tgtcaattaa gtttgtaaac aaattccgtt ttctaacggc taggtaggag ataaatgtcg
    60421 caaatagaac aactagaact aaggcaatca aagggatacg aatggtattg aaaatagcag
    60481 atcccatacg atggaaagct accttgtaac tgtttggaga ataaccttta acagatacca
    60541 tacctgatgt ttttaggaaa gaggtataaa ttaagtagat ttgaggtaaa acagagataa
    60601 agataattcc gtagactgtt gcataaatgg cagctatttt tccttttgta gtttttttag
    60661 gctcaattgg atggagcaga ttcatgctga aactgtagcg gtttgcaatg tgtttttgga
    60721 taaggaaaat tgccaaggca atgataatcg ccataattgc aaaagcagaa tttcctccaa
    60781 cctcgctaat aaattgggta taaatcagga cagggaaagt ccgatatcct tcgccaatca
    60841 acataggcgt tccaaagtct gagaatgctc tcataaatac aagcaaggag ctgctagtaa
    60901 ggttggaact aggagaggta aaacaaccgt tacgatacgc ttaaatccga aggaccccca
    60961 tgctttcagc tgcttcaagt agagaattgt caatactgtt cattgttcca gcaacatata
    61021 gaaataccag tgggaatagt tgcagtgtaa agacaagtac aattcctttg aatccataaa
    61081 tatcgatagc tggaagatga agggcatttg tcaaaaattt agtgatgacc ccatttcgtc
    61141 ctagcaagag aacccaggag taggctccta cgaaaggagc tgacatggaa gcaatgataa
    61201 tcaatatttg tagaaatttc tcccccttga agtcatacat agagaagaga taagctaata
    61261 gggttcctac aactaaggaa gtgacagtag cggtaatgga aaccttgaaa ctgttgacta
    61321 gtgtctcaga gtagtagact ttactaaaga aagtgacaaa attagctagt gagaattatc
    61381 cttcatgtat aagtgcttac ttgagcacgg taatgatagg ataaacgaga aagacaagat
    61441 aggtaagaaa gatgaagaaa gaggaggctg tccaaatatt tagtttttta cattccatgg
    61501 ttgactcctt ttatcaggtt ttgggaacca tctgcagaaa agatgtttaa tttttgcgta
    61561 ttgattcgta gacgaatacg attgtctttt tgtagatctt cttcaaaagt tgattcttca
    61621 ctaacttgaa tttttgaggc aaaacctgtc tcaatgaaat actccgtatt tagtccaaga
    61681 tagacgctat cgctaatagt tccttcgata tctccagatt catctttgat aaactcttcg
    61741 ggacgaatgc ttacatgaat agcttgctcc tcaacctgat caagagctag cattcgaagg
    61801 gcatagccat ctgaaaaaga cgatataagc gccgtcgctc cgtttttcaa gattggcagg
    61861 gataatattt gtgcgtccga taaaggttgc cacaaactca ttagctggtt tatgatagag
    61921 ttcttttggt cggccgattt gttggatcac cccatctttc ataacagcaa tttggtctga
    61981 aatagccatg gcttcttctt ggtcgtgggt tacataaaca gttgtaattc ccacttcgtg
    62041 ttggatttct cggatggctt gacgcatatc caagagaagt ttggcctcca gattactaag
    62101 tggctcgtcc atgaggagaa cacttggatt aaccgctaag gcgcatgcca aggtgacacg
    62161 ttgttgttgt ccaccactga gtttatcggg ctttcgatcc gcatattgag caatttgcat
    62221 gagttcaaga tacttgttgg tctgttgaat caattcttct tttggaacct tcttttgcat
    62281 aagaccaaaa gcaacgttgt ctcgaacagt caaatgtggg aaaatagcgt agttttggaa
    62341 aaccatcccg atattgcgtt tgctgggttc catattattg atttttgtat catcgaagta
    62401 aaattctcca tctttgatac tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc
    62461 acatcctgaa gctccaagaa gggtaaagag acttcctttt ggaattgtaa tgttcaaatt
    62521 ctcaataaca gggacatcgt ggtagatttt tttggcgtta ataatttcga tctcactcat
    62581 agtgaacctc ttttactgtt tagattggat atctgtaaag acttcgttgt atttcttaac
    62641 gatatctgat ttattcttga tgacataatc ataatcttca gtgagtgttt tgattttgtc
    62701 aattggtttc atgttttcgc ttgttttagc atttttacga acaggacggt tagtagtggt
    62761 tgtaccaagt gtatcttgta cttcttgaga gataataaaa tcgataaatt tcttggcatt
    62821 ttccatattt ttagattttt taacgatagc agcactagca ggtaggaaga cggttccttc
    62881 ttttggatag actaccttaa tgttagctcc gtcatttaag agtttaactg ctggatcttc
    62941 ataagagaga ccaacagtca tttctccatc agcgactgct ttatagacac cagatgaact
    63001 taaaccgatt ttatagtata ttgaaactag aatagtacac atctacttct aaaatattgt
    63061 tagaaatcga tttgactgtc ctgattaatt tgtcctattc ttatttcatt ttactatacc
    63121 atcaataagt gtgaaaagat cttttacata agaccaagcc ttatcatctt tgtaaccacc
    63181 ttgagcttgt agcatatttg ttaattgagc aaaggcgcta gaagagtttg ctgggtcagc
    63241 agttgcgatt ttttctttta gttcaggttt gagaagatcg ttatatcctt cgatgttcat
    63301 gcctttagtt aaatcagggt ggacgattaa aacactacca tctagtgtat aaggagtaga
    63361 gaagccagtt gtgttttgat attctttgat aacattatca ttttcttttg aaatatagtt
    63421 ttcaaagagt tctccgtggg tagcatattg tgtataagaa ccaccaaagg taacatcagc
    63481 tacaggaact tctttttctg actctagttt tttgaaaagt tctccagtac cagcttgaat
    63541 cagttctatt ttgataccat atttttcttc aaaggcagga atagttgctc caattaagcc
    63601 ttctgagttt ggtgaataaa cgactagcga accaccgtct cctttatcag atgaactgtc
    63661 atcggcagat tcattagaag aacaagcagc ataatacatc catttctttt tcatgatgga
    63721 tacctccgtt gtgttattta agtttatttt aaaacaatgt aagcgttttt aaaacctaca
    63781 attcta
//
LOCUS       DAVLUM010000002        51043 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLUM010000002 DAVLUM010000000
VERSION     DAVLUM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.002"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..713)
                     /locus_tag="VYN42_000080"
     CDS             complement(<1..713)
                     /locus_tag="VYN42_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1461235.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIS"
     gene            complement(771..1952)
                     /locus_tag="VYN42_000081"
     CDS             complement(771..1952)
                     /locus_tag="VYN42_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1461236.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            2135..2614
                     /gene="rlmH"
                     /locus_tag="VYN42_000082"
     CDS             2135..2614
                     /gene="rlmH"
                     /locus_tag="VYN42_000082"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1461237.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            2658..2731
                     /locus_tag="VYN42_000083"
     tRNA            2658..2731
                     /locus_tag="VYN42_000083"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2692..2694,aa:Arg,seq:tct)
     gene            2896..3021
                     /gene="comC"
                     /locus_tag="VYN42_000084"
     CDS             2896..3021
                     /gene="comC"
                     /locus_tag="VYN42_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1461238.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            3042..4367
                     /locus_tag="VYN42_000085"
     CDS             3042..4367
                     /locus_tag="VYN42_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1461239.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVIFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            4364..5116
                     /locus_tag="VYN42_000086"
     CDS             4364..5116
                     /locus_tag="VYN42_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1461240.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            5168..5239
                     /locus_tag="VYN42_000087"
     tRNA            5168..5239
                     /locus_tag="VYN42_000087"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5201..5203,aa:Glu,seq:ttc)
     gene            5245..5318
                     /locus_tag="VYN42_000088"
     tRNA            5245..5318
                     /locus_tag="VYN42_000088"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5279..5281,aa:Asn,seq:gtt)
     gene            complement(5359..5901)
                     /locus_tag="VYN42_000089"
     CDS             complement(5359..5901)
                     /locus_tag="VYN42_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1461241.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            6080..6847
                     /locus_tag="VYN42_000090"
     CDS             6080..6847
                     /locus_tag="VYN42_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1461242.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            6932..7207
                     /locus_tag="VYN42_000091"
     CDS             6932..7207
                     /locus_tag="VYN42_000091"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461243.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFLQQYQQI"
     gene            7297..7611
                     /locus_tag="VYN42_000092"
     CDS             7297..7611
                     /locus_tag="VYN42_000092"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1461244.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(7712..10264)
                     /locus_tag="VYN42_000093"
     CDS             complement(7712..10264)
                     /locus_tag="VYN42_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1461245.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSYYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIENQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(10326..11948)
                     /locus_tag="VYN42_000094"
     CDS             complement(10326..11948)
                     /locus_tag="VYN42_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1461246.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            12154..13179
                     /gene="trpS"
                     /locus_tag="VYN42_000095"
     CDS             12154..13179
                     /gene="trpS"
                     /locus_tag="VYN42_000095"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1461247.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEENKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSGVKGA
                     MGLHYFN"
     gene            13331..14809
                     /gene="guaB"
                     /locus_tag="VYN42_000096"
     CDS             13331..14809
                     /gene="guaB"
                     /locus_tag="VYN42_000096"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1461248.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(14860..15957)
                     /gene="recF"
                     /locus_tag="VYN42_000097"
     CDS             complement(14860..15957)
                     /gene="recF"
                     /locus_tag="VYN42_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1461249.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNRN"
     gene            complement(15960..16328)
                     /locus_tag="VYN42_000098"
     CDS             complement(15960..16328)
                     /locus_tag="VYN42_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1461250.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SCRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            16487..17737
                     /locus_tag="VYN42_000099"
     CDS             16487..17737
                     /locus_tag="VYN42_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1461251.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            17734..19017
                     /locus_tag="VYN42_000100"
     CDS             17734..19017
                     /locus_tag="VYN42_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1461252.1"
                     /translation="MTKVVFEKKYYPAVKEMIYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            19059..19880
                     /locus_tag="VYN42_000101"
     CDS             19059..19880
                     /locus_tag="VYN42_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1461253.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            19891..20436
                     /gene="pgsA"
                     /locus_tag="VYN42_000102"
     CDS             19891..20436
                     /gene="pgsA"
                     /locus_tag="VYN42_000102"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1461254.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            20433..21260
                     /locus_tag="VYN42_000103"
     CDS             20433..21260
                     /locus_tag="VYN42_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1461255.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVIFITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            21245..22084
                     /locus_tag="VYN42_000104"
     CDS             21245..22084
                     /locus_tag="VYN42_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1461256.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRIFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            22077..22871
                     /locus_tag="VYN42_000105"
     CDS             22077..22871
                     /locus_tag="VYN42_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1461257.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            22930..23748
                     /gene="mreC"
                     /locus_tag="VYN42_000106"
     CDS             22930..23748
                     /gene="mreC"
                     /locus_tag="VYN42_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1461258.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            23748..24242
                     /gene="mreD"
                     /locus_tag="VYN42_000107"
     CDS             23748..24242
                     /gene="mreD"
                     /locus_tag="VYN42_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1461259.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            24336..25514
                     /locus_tag="VYN42_000108"
     CDS             24336..25514
                     /locus_tag="VYN42_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1461260.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            25738..26517
                     /gene="rpsB"
                     /locus_tag="VYN42_000109"
     CDS             25738..26517
                     /gene="rpsB"
                     /locus_tag="VYN42_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1461261.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAALETQADSIEEIVEVVEGDNA"
     gene            26596..27636
                     /locus_tag="VYN42_000110"
     CDS             26596..27636
                     /locus_tag="VYN42_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1461262.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            27882..28169
                     /gene="tnpB"
                     /locus_tag="VYN42_000111"
     CDS             27882..28169
                     /gene="tnpB"
                     /locus_tag="VYN42_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1461263.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(28360..28647)
                     /locus_tag="VYN42_000112"
                     /pseudo
     CDS             complement(28360..28647)
                     /locus_tag="VYN42_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            28638..29036
                     /locus_tag="VYN42_000113"
     CDS             28638..29036
                     /locus_tag="VYN42_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1461264.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEGWARM
                     GLPITRKEIVNWHIKASQYYLEPLYNLLRERLLTQSLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(29233..30153)
                     /gene="cysK"
                     /locus_tag="VYN42_000114"
     CDS             complement(29233..30153)
                     /gene="cysK"
                     /locus_tag="VYN42_000114"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1461265.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(30438..31073)
                     /locus_tag="VYN42_000115"
     CDS             complement(30438..31073)
                     /locus_tag="VYN42_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1461266.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            31129..32427
                     /locus_tag="VYN42_000116"
     CDS             31129..32427
                     /locus_tag="VYN42_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1461267.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLDLYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            32424..33086
                     /locus_tag="VYN42_000117"
     CDS             32424..33086
                     /locus_tag="VYN42_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1461268.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            33166..33714
                     /gene="raiA"
                     /locus_tag="VYN42_000118"
     CDS             33166..33714
                     /gene="raiA"
                     /locus_tag="VYN42_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1461269.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            33850..35823
                     /locus_tag="VYN42_000119"
     CDS             33850..35823
                     /locus_tag="VYN42_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1461270.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDTFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            35820..36272
                     /gene="rplI"
                     /locus_tag="VYN42_000120"
     CDS             35820..36272
                     /gene="rplI"
                     /locus_tag="VYN42_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1461271.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            36316..37668
                     /gene="dnaB"
                     /locus_tag="VYN42_000121"
     CDS             36316..37668
                     /gene="dnaB"
                     /locus_tag="VYN42_000121"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1461272.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            37670..37936
                     /locus_tag="VYN42_000122"
     CDS             37670..37936
                     /locus_tag="VYN42_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461273.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            38025..39371
                     /gene="cbpD"
                     /locus_tag="VYN42_000123"
     CDS             38025..39371
                     /gene="cbpD"
                     /locus_tag="VYN42_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1461274.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      39454..39556
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            39627..39917
                     /locus_tag="VYN42_000124"
     CDS             39627..39917
                     /locus_tag="VYN42_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1461275.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            39880..40638
                     /locus_tag="VYN42_000125"
     CDS             39880..40638
                     /locus_tag="VYN42_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461276.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            40676..41683
                     /locus_tag="VYN42_000126"
     CDS             40676..41683
                     /locus_tag="VYN42_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1461277.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            41683..42411
                     /locus_tag="VYN42_000127"
     CDS             41683..42411
                     /locus_tag="VYN42_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461278.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            42530..42988
                     /locus_tag="VYN42_000128"
     CDS             42530..42988
                     /locus_tag="VYN42_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1461279.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            42990..45422
                     /locus_tag="VYN42_000129"
     CDS             42990..45422
                     /locus_tag="VYN42_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1461280.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKLLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            46064..46717
                     /gene="rr06"
                     /locus_tag="VYN42_000130"
     CDS             46064..46717
                     /gene="rr06"
                     /locus_tag="VYN42_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1461281.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            46714..48054
                     /gene="hk06"
                     /locus_tag="VYN42_000131"
     CDS             46714..48054
                     /gene="hk06"
                     /locus_tag="VYN42_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1461282.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            48149..48676
                     /locus_tag="VYN42_000132"
     CDS             48149..48676
                     /locus_tag="VYN42_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1461283.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            48755..>51043
                     /locus_tag="VYN42_000133"
     CDS             48755..>51043
                     /locus_tag="VYN42_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV1461284.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGIT
                     QVATSYNKANESQTEHRKAAKQVDEDIKKMLSEIQEYIKKMLSEIQLDKRKDTQNRTL
                     NRKLSAIQTKYLYELRVLKEKSKKEELTSKTKKELDAAFEKFKKEPELTKKLAEAKQK
                     AKAQKEEDFRNYPTNTYKTLELEIAEFDVKVKEAELELVKEEAKPRNEEKIKQAKEKV
                     ESKKAEATRLEEIKTERKKAEEEAKRKAEESEKKAAEAKQKVDTKEQGKPKRRAKRGV
                     SGELATPDKKENDAKSSDSSVGEETLPSPSLNMANESQTEHRKDVDEYIKKMLSEIQL
                     DRRKHTQNVNLNIKLSAIKTKYLYELSVLKENSKKEELTSKTKAELTAAFEQFKKDTL
                     KPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELV
                     KEEANESRNEEKIKQAKEKVESKKAEATRLEKIKTDRKKAEEEAKRKAEESEKKAAEA
                     KQKVDAEEYALEAKIAELEYEVQRLEKELKEIDESDSEDYLKEGLRAPLQSKLDTKKA
                     KLSKLEELSDKIDELDAEIAKLEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAE
                     ADLKKAVDEPETPAPAPQPAPAPEKPAEKPAPAPEKPVEKPAPAPEKPVEKPAPAPAP
                     EKPAPAPEKPAPTPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMA
                     TGWLQNNGSWYYLNSNGAMATGW"
BASE COUNT        16284 a         8266 c        10767 g        15726 t
ORIGIN      
        1 aaagaaataa tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg
       61 agtagttttc ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc
      121 ttttgttttt tctctgtcag aagagcttct aacttcctta cagaaatatc ttcttctata
      181 atccgttgaa agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg
      241 gcttgtgata gtttgccatt ttctacttct gagagaatct gttctggcaa ggaaagtaaa
      301 cgaatggagt tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg
      361 gtgaatcctt tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt
      421 tctctctgta aattttcaat aatggactgg accatcatct cttggtctga aatctgttta
      481 acaacagctg ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct
      541 gcaaggattt cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca
      601 ttttctttga tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt
      661 tgatagggat ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta
      721 cactaacaca tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct
      781 aaatcacctg aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag
      841 taggttatct taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt
      901 gatgaagcaa tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca
      961 ttggcaggca tattactttg taccgaacga acaattacac cagatgtaac attacttgga
     1021 atattgagtc ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc
     1081 aaagctggac gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca
     1141 tttgcaggaa ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta
     1201 cttgaggtaa ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct
     1261 gggttaatag cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat
     1321 tttaaggata catttctatt gagactggat acgatacctt gagtgacagt atttgcatat
     1381 tcagaaccta acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa
     1441 tcaccaaact cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca
     1501 gagaaagtgt cagctccgac aatttttcca ggtactttag tcccatctga caatcgaata
     1561 tctactttgc tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca
     1621 ttctttttat aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta
     1681 tcatcattgc caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca
     1741 gcatctttta ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt
     1801 gtaatagtac tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt
     1861 gaaaaactac ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac
     1921 cattttttgt aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga
     1981 aagtataaac tgactagctt aattataact taaacacaaa agttttacac aaactgtgga
     2041 taactctttt gaaattgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga
     2101 tgtgaaaaaa tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg
     2161 gaaactgaaa gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag
     2221 atttgctaag tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga
     2281 atcagaaaat caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga
     2341 ccgtgatttc gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag
     2401 taagcagtta gaagaaactt ctataaaagg attttctact cttactttta ttattggggg
     2461 aagtttagga ttatcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg
     2521 cctaacctta ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt
     2581 tacgattcag cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg
     2641 gtagaataat tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga
     2701 acggtcgcag gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg
     2761 gcttttttct taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc
     2821 taaaacgaaa ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt
     2881 ttaggagatt ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa
     2941 aaagacttac aaaagattaa aggtggggag atgaggattt caagaatcat ccttgatttt
     3001 cttttcctac gaaaaaagta atgaaataag gagaaagagt aatggattta cttggatttg
     3061 ggacagttat tgttcatttt ttaattatta gtcacagtta ccgtttaatt tgtaaaggtc
     3121 gaataaatag aaaagaatta tacgtttttg gtgcttatac attactaact gaaatagtac
     3181 ttgaattttc cttttatctt ctatatttag ataaaatagg gattgaaaga tttttatttc
     3241 ctttgggctt atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat
     3301 tcctaagttt actactatct cttttatatg agagcactca taactttctg tccgtaattt
     3361 tctcctctat aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg
     3421 tgacggtgtt aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag
     3481 cctattttga caaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat
     3541 tgctacatat tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt
     3601 ttggaagtat tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga
     3661 attctcataa agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga
     3721 aacatttaca gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc
     3781 gacatgatta tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac
     3841 aggaaattga cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag
     3901 ataagtacac ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg
     3961 ctcagtcaat tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata
     4021 cgattaccaa gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga
     4081 ataatgctgt cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta
     4141 agatggaaac tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt
     4201 caggagatct atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa
     4261 ataatgtgaa agaactacta gataagtaca acaatattat tttagaaaca gagatggaag
     4321 gcagtacatt tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt
     4381 agaagatgtt attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga
     4441 atcgaatatt ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat
     4501 tgaaaatgat gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa
     4561 aaagggattt gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt
     4621 tatcactagt cgatcagagt ttgcgactct aacctataaa taccaggtat cagccctaga
     4681 ttttgttgat aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt
     4741 ctacacgaag agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta
     4801 caagggaaat gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt
     4861 atctcataaa ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac
     4921 agatattcag gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt
     4981 ggtaaatata ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga
     5041 agaccatcgt tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa
     5101 aaaatctcaa aagtgattga caattagcaa gaaattgata taatggttat atctgctaca
     5161 gatagaaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt
     5221 tcgaatcccg tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt
     5281 taatcatgat gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc
     5341 tgtgttcctc tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat
     5401 ttcttgagaa ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc
     5461 atgagttaga tagatgctac tatattctaa ttcagtggta tttagattca gttgcataaa
     5521 tcgcttttgt aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat
     5581 ttctttagtc ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc
     5641 aaaaacttct aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa
     5701 tgtatggaat agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt
     5761 atagaagctg gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc
     5821 aaatggctgt tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa
     5881 gcgtttgtta ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa
     5941 atatattttt tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt
     6001 agacaatgtg tttaaaaaag gagaaattat gtttaaagaa tggaaagcaa tttaaaaaaa
     6061 accaaccttt attattgtca tgatcgggat ttctcttatt ccagctctgt acaatatcat
     6121 atttttgtca tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt
     6181 aaataatgat aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt
     6241 gtccaattta aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa
     6301 gaagggattg gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga
     6361 aaaaacaact acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga
     6421 gcaacaaact gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc
     6481 tcagtcaatt gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca
     6541 atcttctaat ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac
     6601 ttctttgata ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt
     6661 agttcctgcc agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa
     6721 agtttctcag ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga
     6781 taaactagtt tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt
     6841 tggttaatta caatcaggat ctgggcaatt agcagacaaa tccagttagt tactttcagg
     6901 tgcttctcca ttagagaata gagctaataa attggcagat ggatctggga aactagcaga
     6961 aggtggaaca aagttaactt ctggattgga agatttacag acaggacttg cttctttagg
     7021 acaaggacta ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc
     7081 agagattttg tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa
     7141 tggaatcgca atagctcctt atatgatatc agttgctctt tttttgcagc aatatcaaca
     7201 aatatgatat ttgcgaaatt gccttcagga cgtcatccag agagccgttg ggcttggttg
     7261 aaatcttgag ctgaaataaa tggtattata gctgttttgg caggaatttt ggtatatgga
     7321 ggagttcagc ttattggttt aactgctaat catgagatga gaatatttat tctcatcatc
     7381 ctaacaagtt tagtattcat gtctatggtg accactttag caacgtggaa tagccgtata
     7441 ggagcttttt tctcacttat tttgctttta ctacagttag catcaagtgc aggtacttat
     7501 ccacttgctt tgacaaatga tttctttaga tctattaatc cctggttacc aatgagctat
     7561 tcagtttcgg gattacgaca aacaatctct atcaacaagt cattttccta gctgtcatac
     7621 tagttctatt tactagttta ggtatgctag cctatcaaca taagaaaatg gaagaagatt
     7681 aaaaaaatcg accgattaac tggtcgattt tttatgcctt agatgacttt cgtctgtgat
     7741 tatagattcc aaatagtaag agagaagtaa aggaacagat tgctccagta ataaaaccat
     7801 tgggaatgaa ggaaagtgta atagttcctt tccccttggg aatgtcaact ttcataaatc
     7861 cagtttgagc ttgtttaatt tctattttct taccatcttg gtaggcagac caacctttgt
     7921 cataaggaat ggtgaagaaa atagatgtat cttgttggac atcatatgta gcaaaaacct
     7981 tgtttttaga agttgatact gtgacaggtt gttctttaat tttttgaatt gcctcggtga
     8041 aagttttggt atctaaacga tagaaggtag gagattcaaa tgatacttgt gaatttccag
     8101 ggaaactaac attgatattg aaagtttttt tctctttagt atatcctaga ttaaagaagg
     8161 agaagacatt atcagttgta aaagtctttt tttcaccatt tacaaggatg tcaaccttct
     8221 tttgtttatc gttagaaaag tgaaggttta tgaaagagag ataaacttgg ctgttttctg
     8281 gaacttcaat ttgatactgg attgctgcat cttcatttga agaacttgtt acactaatca
     8341 aatcattagt attttctatt ttttctgttt tttcataagg tattggagaa aaataatcaa
     8401 aattgacgtt agcaagttga tttaaaaatg aggcctgatt atccaaggta tgttcattga
     8461 acttgacatc attgtaaaca gattgactag caactgcaat cggaagagag tattgatttt
     8521 catatagggt aagattatct ttttgataga tatctttaaa accatactta tcaataggac
     8581 tgtctgagat attgtactgg ataccaaata aactatcagc caaaatacta ttatttgcat
     8641 atcggagatt gagattagtc ccagaggatt taaaaccaag tttatctaaa gtagagcttg
     8701 atgaacgatt tcgaacagat gaaaattgag agattccatt gtagttgaat ttcatactgt
     8761 catttcctgt ctgagtttgt agtttttcag tacgagtaaa ttgattttca atatatgttg
     8821 agaaagattc catagctggg atatctcgac tataagcact tcgagaagca aatccccatt
     8881 ccttagcaat tccgtccatt tgagatgaag catttaaact catttcaacc agtataaata
     8941 aagagattag aatggcaaat agattcacag atataaactt tttgataact gcaaggagta
     9001 aaagagaata gacaaccaaa aattcaagag taagcagaat attcaaatct gttaaaaaag
     9061 aataatacga ttttagatag atggtagcta aaaatcctgt tactacaaga aaaagcgaaa
     9121 ctaaaaaatt ccagacttta agttctttca gacgctttaa gacttctgct gctgtgtaaa
     9181 ttaacaaggt agagaaaatc caagcatagc gatgtaaaaa catgtttgga gtatgcatgc
     9241 cttgccaaaa taagtcaaga gcttctatgt aaaagcttgc aattagaaat gcaaagaata
     9301 ttacatatat gagtttcacg tgaaacttaa tagatttcag cgtaaaaaat aaaatggtca
     9361 aaataaaggg aagtagtcca acaaaaatca ttgggatggc cccatacttt gttgtgtcaa
     9421 aggaaccaat gaattgctta gcaaagagat caagatacca gctactttca gtttgaaact
     9481 ttgtaacttc agtcaatttt tccccatgtg tctgtaaatc aaatagagtg ggaagagtca
     9541 taatcaaact agccatacca gctaaaaagg agataactat gaaatcaaga acagatgatt
     9601 ttcgagtctt aaagtcccac gaaatttgac agagatacca gaaaataaga aacaatactg
     9661 tcatatatcc aaaataataa ttttgaataa ataagattga cagacttgta aagtacaata
     9721 ggagtttctt ttcagttatc agtagatgta aaccagttat aattaaagga atcaagataa
     9781 aaacatctag ccaggttttt atctctaatt gactgacagt gaaactcatc agagcatagg
     9841 aagtagataa ggctagtttt aaagtctgag ggatagattg aaacaattta ttcaaactaa
     9901 aaaaggttga cagaccaatc aatccaaatt ttaagagagt ggtcagatag acagcatctg
     9961 gcatattcgt tagatcaaaa aagtaaacca gaggcgcgag aaaactaccc aagtaataac
    10021 tagatagggc atagaagttt agccctagac cacttgtaaa ggtgtaaaac agactactat
    10081 ttccatgtag gatatttcgt aaggctacat caaaaataac gtattgatga aagccatctc
    10141 ctaatagagg agagttgtcg ctattccagt agataccttg agatagatat actccagaca
    10201 taatcactac aggaatgatg aaagaaataa aataggttcg atatgttttt aaaaatgatt
    10261 tcatgttacc tcgtagaatg atagaaaact cagttggtta acccaactga gttttgaagt
    10321 tttatttagt ctttccaaag ttctttaact tttgcttgta cttctgcatt ttctaggaat
    10381 tcatcgtagg tttcatcgat acggtcaatg acgccatttt tagataagac aatgatatga
    10441 ttagccaaag tttgaataaa ttcgtggtca tggctggcaa agatgattga ttctttaaag
    10501 tttttcaatc catcattcaa gcttgagata gattccaagt ccaagtgatt tgttggatca
    10561 tcaagtacaa ggacatttga ttttaagagc atgagttttg aaagcatgac acgaactttt
    10621 tctccccctg acaagacatt tacaggtttg ttaacttcat ctccagagaa gagcatacgg
    10681 ccgaggaagc cacgtaggaa agtattgtca tcttcttctt tacttgcgaa ttgacgcaac
    10741 cagtcaagaa ttgattctcc tcctgcaaaa tcagctgagt tatcttttgg taggtaagat
    10801 tgactagttg taactcccca cttgacagtt ccttcatagt caatatctcc catgattgca
    10861 cgaattaatg cagtcgtttg aatatcattt tgtccaataa gtgctgtctt atcatctgga
    10921 cgcaagatga aactaatatt atccaagata gtttcaccat caatctttac agttagattt
    10981 tctactgtca agagatcatt accaatctca cgttccgctt taaagttgat aaatggatat
    11041 ttacgactag atggtacaat ctcttctagc tcaatcttat caagcatttt cttacgtgat
    11101 gttgcctgcc ttgacttaga agcattggca gagaaacgag caacgaattc ttgcaattgt
    11161 ttaatttttt cttctgcttt agcattacgg tctgctagca atttagcagc aagctcagaa
    11221 gattccttcc agaagtcgta gtttccgaca tagagtttga tttttccaaa gtcaaggtcg
    11281 gccatgtgag tacaaacttt gtttaagaag tgacggtcgt gggatactac gataactgtg
    11341 ttatcaaagt caatcaagaa gtcttctaac caagtaatcg attggatatc caaaccgtta
    11401 gtaggctcgt ccaagagaag aacatctggt ttaccaaaaa gtgctttggc gaggagaacc
    11461 tttacttttt caccgttggc caattcgctc atgttttggt agtgtaattc ttctggaatg
    11521 tttaggtttt gaagtagttg agaggcttca ctctctgctt cccaacctcc aagttcggca
    11581 aactctcctt cgagttcggc agcacgaacc ccgtcctcgt ctgagaaatc ttccttcatg
    11641 tagatagcat ctttctcttt catgatgcta taaagttttt catttcccat gataacgaca
    11701 tcaatggcac gttcatcttc gtagtcaaag tgattttgac gaagaacaga gagacgttca
    11761 tctggaccaa gagagatgtg accagtagta ggttcgatat ctccagctaa aatttttaaa
    11821 aaggttgatt ttccggcacc attagcaccg attaatccgt aagtatttcc ttctgtaaat
    11881 ttgatattga catcatcaaa aagtttgcga tcactaaaac gtagtgaaac atcagatact
    11941 gtaagcaatg tttttctcct atatgtgtaa tatatttatt ctactagaaa atacagaaat
    12001 attcaaattt ttatttgtca attttgtgta aattatattt acagtatcct ttacacaaat
    12061 ctgtaaaaag caaggctgat ttattttgat aaattacggt tatttcatta aaaaaatgct
    12121 ataattgaaa ggactatatc gaaggagaac aaaatgacta aacccattat tttaacagga
    12181 gaccgtccaa caggaaaatt gcatattgga cattatgttg gaagtctcaa aaatcgagta
    12241 ttattacagg aagagaataa gtatgatatg tttgtgttct tggctgacca acaagccttg
    12301 acagatcatg ccaaagatcc tcaaaccatt gtagagtcta tcggaaatgt ggctttggat
    12361 tatcttgcag ttggattgga tccaaataag tcaactattt ttattcaaag ccagattcca
    12421 gagttggctg agttgtctat gtattatatg aatctagttt cgttagcacg tttggagcga
    12481 aatccaacag tcaagacaga gatttctcag aaaggatttg gagaaagcat tccgacagga
    12541 ttcttggtct atccaatcgc tcaagcagct gatatcacag ctttcaaggc taattatgtt
    12601 cctgttggaa cagatcagaa accaatgatt gagcaaactc gtgaaattgt tcgttctttt
    12661 aacaatgcat ataactgtga tgtcttggta gagccggaag gtatttatcc agaaaatgag
    12721 agagcagggc gtttgcctgg tttagatgga aatgctaaaa tgtctaaatc actaaataat
    12781 ggtatttatt tagctgatga tgcggatact ttgcgtaaaa aagtaatgag tatgtataca
    12841 gatccagatc atatccgcgt tgaggatcca ggtaagattg agggaaatat ggttttccat
    12901 tatctagatg tttttggtcg tccagaagat gctcaagaaa ttgctgatat gaaagaacgt
    12961 tatcaacgag gtggtcttgg tgatgtgaag accaagcgtt atctacttga aatattagaa
    13021 cgtgaactgg gtcctattcg tgagcgccgt attgaatttg ctaaggacat gggagaagtt
    13081 tataatatga ttcaaaaagg tagtgaaaga gcgcgtgaag ttgcgggtca aaccctatct
    13141 ggggtaaaag gggcaatggg acttcattac tttaactaag tttattttac aagaaactat
    13201 cttttctatc tcgaagaaaa gatagttttt tatttacccc tgtaacattt gacaaatttt
    13261 tatagaatgg tatgatagat acaatataaa aagagtcaag ctcaaaaaga aagaaaagag
    13321 gaaacttcga atgtctaatt gggacactaa atttttgaaa aaaggtttta cctttgatga
    13381 tgtattgctt attccagctg aaagtcatgt gttgcctaac gatgcagatt taacaactaa
    13441 attggcagat aatttgactt taaatatccc aattattacc gctgccatgg acacagttac
    13501 agagagtcaa atggccattg ctattgctcg tgcaggcggt ctcggagtta tccataaaaa
    13561 catgtcaatt gctcaacaag cagacgaggt tcgtaaggta aaacgttctg aaaatggagt
    13621 tattattgat ccgttcttct tgacgcctga acatacaatt gctgaagcag atgagcttat
    13681 gggtcgttac cgcatcagtg gtgttccagt tgttgaaaca cttgaaaatc gtaaattggt
    13741 tggtattttg acaaaccgag atcttcgttt tatttcagat tataatcaac caatttcaaa
    13801 ccatatgact agtgaaaatc ttgttactgc acctgtgggt acggatcttg caacggctga
    13861 gagtattctt caagagcatc gtattgaaaa acttccgttg gttgatgaag aaggcagtct
    13921 ttctggtttg atcactatca aagatattga aaaagttatt gagtttccaa atgcggctaa
    13981 agatgagttt ggtcgtcttc tagttgcagg tgcagtaggt gttacttcag atacatttga
    14041 acgtgcagag gctctttttg aggcaggagc ggatgcgatt gttattgata ctgcacatgg
    14101 tcattctgca ggtgtcttgc gtaaaattgc cgagattcgt gctcatttcc cagatcggac
    14161 tttgattgct ggaaatattg ctactgctga aggtgcacgt gccctttatg aagcgggtgt
    14221 agacgttgtt aaggttggta ttggaccagg ttctatctgt actactcgtg tgattgctgg
    14281 tgttggtgtt ccgcaagtaa cagctatcta cgatgctgca gctgttgcgc gcgaatatgg
    14341 taaaacgatt attgctgacg gtgggatcaa gtattctgga gatattgtaa aagcacttgc
    14401 tgcaggtgga aatgctgtta tgcttggatc tatgtttgct ggaactgatg aagctccagg
    14461 cgaaactgaa atcttccaag gacgtaaatt caaaacttac cgtggtatgg gatcaattgc
    14521 tgctatgaag aaaggttcaa gcgaccgtta tttccaaggt tctgtcaatg aagcaaacaa
    14581 gctcgttcca gaaggaattg aaggtcgtgt tgcttataaa ggagcggcag ctgatattgt
    14641 tttccaaatg attggtggta ttcgctctgg tatgggttac tgtggtgcag ctaaccttaa
    14701 agaactacac gataatgctc aatttattga aatgtctggt gctggtttga aagaaagcca
    14761 tcctcatgat gtgcaaatta ctaatgaggc accaaattat tctatgtaaa aaacaatgaa
    14821 aagaactcca gtgaaaacag gagttctttt acaatgttgt caatttctat ttacagcagc
    14881 tttaccatcc tgaatagtga agatacttag attttctggc agattttgaa gatggtctaa
    14941 gcttgttgtt gtgataaagg tttggattga ttgagaaatc gtttctaata attttaactg
    15001 tctagtgttg tcaagttcac tcatcacatc gtcaagcagt aatatcggag attctgtggt
    15061 aatgctttcc attaattcga tttctgctaa ttttatcgag aggacgagac tacgatgttg
    15121 accttggctt ccgaaactag catccatccc atttatataa aaagaaatgt catctcgatg
    15181 aggaccgaca ccagtattct ttttaaataa atctctggat ctactttttt ctaaagcaat
    15241 tttgaaagat tcggataagt tttgtttgtc agttatattg acagaagatt gataggatat
    15301 tgacaactct tcgatctgat tagagagttc aaaatgtttc ttacgcccaa atgattctag
    15361 tttttttatg aaatctaagc ggtgattcat tacacgacat ccataatcaa ctagctgatc
    15421 atctaacaca gaaaggaatg tttcatctat tttttgagct gattttaggt aagtgtttct
    15481 ttgctttagg atgtggttat aattggttaa gtcagataaa tagattggct taatttgccc
    15541 aagttccata tcaatgaatt ttcgtcgaat cgaaggtgct cctttaatta gttgtaaatc
    15601 ttcaggagca aataagacaa cattcatgtg tcctacataa tctgaaaggc gtgcctgttt
    15661 taagtgatta acttttgtta cacggccttt ttgtgttagt tcgatttcta ggggaatgga
    15721 tccagttttt ttctgaacga gacctgaaag atgaagttgt tcctcatcaa aatgaatgag
    15781 atttttatct gttcgagttc gatgactacg cgttaaggct aaaaaataga tagcctctaa
    15841 catgtttgtt tttccttgtg cattacgtcc caaaaagaca ttcaatttag gattaaagtc
    15901 tattttcgtt tctttgtaat tacgaaaagt cttgagagat agatgttgta gccacatgat
    15961 tatctaccag ggaatcgtgg agcttgttgg cttttaggtg atgaagcagg tttcgatttg
    16021 tcttttttaa ctcccttatt catctttttg acaagtttag cgatccgttc tttttcaact
    16081 ttatcagctt ggtattcatc ttgttcttca gaagtaggtt gtgtcaacaa gatgtcaatg
    16141 ttcatgtcag ggatgtcaac tttatcgcca atacgaagtt tttttccacg acaactctct
    16201 aattccctat taaagtaaac agaatgttca gagagaaatg atttaatagc tcctccgcta
    16261 tgtgtaattc caagttcttt gagtagtgct tggagggtaa taaattcttc aaataatttg
    16321 tattccataa ttcacctcaa tctttggtat tataccatat tttcctaaaa atagtgagag
    16381 agacagctag aaatgtaagc gatttttatt tcaaaagtgt tacagggaac aagaaaattt
    16441 caggttttcg tgatataata gaagtctgta tataaggagg taaatcatgg agttagtgca
    16501 tggaatttca acacatttta tccaatcaaa aaagtttaaa acaaacaaaa ttaccgtgcg
    16561 ttttaccgct ccattatccc ttgatacgat tgcaggtcac atgttgagtg caagtatgct
    16621 agagactgct aatcagatgt accccacttc tcaagatttg aggagacact tggccagtct
    16681 atacggtaca gatatgtcaa ccaattgttt cagaagaggg caaagccaca ttatagaatt
    16741 gacatttacc tatgttcgtg atgagttttt aagtaggaaa aacgtgctaa cctctcagat
    16801 tttggaactt gtaaaagaaa ctcttttttc acccgcagta gttgataatg ggtttgatcc
    16861 ggccttattt gaaattgaga aaaaacaatt gctagcaagt ttagcagctg atatggatga
    16921 ttctttttat tttgcacata aagaattgga taaattgttt tttcatgatg aacgtcttca
    16981 attggaatat agtgatttac gaaatcgtat tttagctgaa actccacaaa gttcttattc
    17041 ttgtttccaa gaatttttag ccaatgatcg aatagatttc tttttcctag gtgattttaa
    17101 tgaggttgaa attcaaaatg tattagaatc atttggcttt aaaggtcgaa aaggagatgt
    17161 gaaggttcag tattgtcaac cttattctaa tatccttcag gaaggtatgg ttcggaaaaa
    17221 tgtgggacaa tccattttgg aattaggtta tcattaccgt tctaaatatg gtgatgaaca
    17281 acatttaccc atgattgtaa tgaatggttt acttggtgga tttgctcact ctaagctctt
    17341 tacaaatgtc cgtgaaaatg ctggattagc ttataccatt tcaagtgagc ttgatttatt
    17401 tagtggattc ttgaggatgt atgctggtat caatcgagaa aatcgtaacc aggctcgtaa
    17461 aatgatgaat aatcaactgc ttgatttaaa aaaaggttat tttacagagt ttgagttaaa
    17521 tcagaccaag gaaatgattc gttggtcgtt gttactttct caagataatc aatcttcatt
    17581 gattgaacgt gcttatcaaa atgccttatt tggaaaatct tcagcagact ttaaaggttg
    17641 gattgcaaaa ctcgagcaag ttgacaaaga tgctatttgt agagcagcta ataatgtgaa
    17701 actacaggcg atttacttta tggaaggaat agaatgacaa aggttgtttt tgaaaaaaaa
    17761 tactatccag ctgtaaaaga aatgatttat cgaactcgtt tggccaacgg attgacagtt
    17821 gctcttttgc ctaaaaagga atttaaagag gtttacggga gtgtcactgt acagtttggt
    17881 tcggtagata cgtttgtcac agaagttgac ggagatgtaa aacaatatcc tgcaggaatt
    17941 gctcattttc ttgaacataa attatttgag agagaagatt ctagtgattt gatgtcggct
    18001 tttacgagtc taggtgcaga tagtaatgcc tttacaagct ttacaaaaac aaactatctt
    18061 ttttcagcaa cggattattt tttagaaaat ttatatttac ttgatgaatt ggtaacatca
    18121 gcacacttta ctgaagcttc cattctgaca gagcaggata ttattcagca agaacgagaa
    18181 atgtaccaag atgatccaga ttcgtgttta ttcttttcaa ctttagcgaa tttgtatcct
    18241 ggtacacctt tagcaactga tatagttgga agtgaggagt ccatttccca aatcaatcta
    18301 actaatttgc aagaaaattt tacaaagttt tacaaacctg taaacatgtc tctgttttta
    18361 gttggtaatt ttgatgtgga gcgagtacag gactattttg aaagcaaaga actgaaagat
    18421 tcagattttc aggaagtagc aagagaaaag ttgtttttac agcctgtaaa gccaacagat
    18481 agtatgagaa tggaagtatc ttctcccaaa ctagcgattg gagttagagg taagcgagaa
    18541 gtttctgaag cggattgcta tcgacatcat attttattaa aattattgtt tgcaatgatg
    18601 tttggttgga cttcggatcg ttttcaaaaa tgttatgaat caggtaaaat tgatgcatcc
    18661 ttatctctgg aagttgaagt aacaagtcgc tttcattttg tcatgttgac aatggatacg
    18721 aaagagccag ttgctttgtc tcatcaattt aggaaggcta ttcgtaattt tacaaaggat
    18781 ttagatatta cagaggaaca tttagatatt atcaaaagag agatgtttgg cgaatttttc
    18841 agtagcatga actctcttga atttattgca acgcaatatg atgcttttga aaatggtgag
    18901 acaatttttg atttgccgaa aattttacag gaaattactt tagaggatgt ccttgatgct
    18961 ggacatcatt taatagatga tggtgacata gttgatttta caatattccc atcgtagtaa
    19021 cctattataa tagacactag aaagaaggga tgacaagtat gagaaaaaaa acaattggag
    19081 aggttttacg attagctaga atcaatcagg gattgagttt agatgaattg cagaaaaaga
    19141 cagaaatcca gttagatatg ttggaagcaa tggaagcaga cgatttcgat caacttccaa
    19201 gtccttttta cacgcgttct ttcttgaaaa aatatgcatg ggctgttgag ttagatgacc
    19261 aaattgtttt ggatgcttat gattctggga gtatgattac ttatgaggaa gtagatgttg
    19321 atgaagatga gttgacaggt cgtagacgtt caagtaagaa aaagaagaaa aaaacatcat
    19381 ttttaccttt attttatttt atcctttttg ctttatcgat tttaattttt gtgacttatt
    19441 atgtttggaa ctatattcaa actcaaccag aggagccttc tctttctaat tacagtgtgg
    19501 ttcaatcaac aagttcaact agctctgttc cccactcctc aagtagtagt tcttctagta
    19561 tagaatcagc tataagtgta tcaggcgaag gaaatcatgt agaaatcgct tataagacaa
    19621 gtaaggaaac agttaaattg caattggcag tttcagatgt tacaagttgg gtcagtgttt
    19681 cagaaagcga acttgagggc ggtgtaacct tatcgccaaa gaagaaaagt gcagaagcaa
    19741 cagttgcaac taaaagtcct gtaacaatta cgttaggtgt tgtaaaaggt gttgatttga
    19801 cagtagataa tcagactgtt gatttatcga aattaacagc tcagactgga caaatcactg
    19861 taacctttac taaaaattaa ggaaaaacga atgaaaaaag aacaaattcc caatctctta
    19921 acaataggtc gaattctctt tatacctatt tttatcttta ttttaacgat aggaaattcg
    19981 atagagagtc atatagttgc agctattatc tttgctgttg ccagtattac cgactattta
    20041 gatggatatt tagctcgtaa atggaatgtg gtcagtaatt ttggtaaatt tgcagatcct
    20101 atggcggata agttactagt tatgtcggct tttattatgt tgattgagtt aggtatggct
    20161 ccggcttgga ttgttgcagt gattatctgt cgtgagttag ctgtgacagg tttaaggctt
    20221 ttattggttg aaactggtgg aacaatttta gcagcagcaa tgcctggaaa aattaaaact
    20281 tttagtcaga tgtttgccat tattttcttg ctattacatt ggactttgct tggtcaagtt
    20341 ctactttatg tagccttatt tttcactatc tactctggct atgactattt caagggtagt
    20401 gcctatgtat ttaaagggac atttggttcg aaatgaaatc aataattgat gtaaaaaatc
    20461 tttcttttcg ctataaagaa aatcagaact actacgatgt gaaggatatt acgtttcacg
    20521 tgaaacgtgg agaatggctt tcgattgtag ggcataatgg tagtggtaaa tcaacgacgg
    20581 ttcgattaat tgatggctta ctggaagcag aatccggaga gattgtaatt gatggccaac
    20641 gtttgactga ggaaaatgtt tggaatatac gtcgtcaaat cggtatggtt tttcaaaatc
    20701 cagacaatca atttgttgga gcgactgttg aagatgatgt tgcttttggt ttggaaaatc
    20761 agggactttc tcgtcaagaa atgaaaaaga gagtagaaga agctctggct ttagttggca
    20821 tgttggactt taaaaagaga gagccagcgc gtctatcagg tggccaaaag caacgtgtgg
    20881 ccattgcagg tgttgtagcc ctaagaccag ctattttaat cttagatgaa gcaacgagta
    20941 tgttggatcc tgaggggcgt agagaactta ttgggacagt aaaaggaatt cgaaaagact
    21001 atgatatgac ggtcattttt attacccatg atttggaaga agtcgccatg agtgatcgcg
    21061 tattggtcat gaaaaaaggg gaaattgaat caactagtag tccaagggag cttttctctc
    21121 gaaatgattt agatcaaatt ggattagacg atccttttgc taatcaatta aaaaaatctt
    21181 tgagccagaa tggctatgat ttacctgaaa attatttgac agaaagtgag ctagaggata
    21241 agctatggga attgctctag aaaatgtgaa ttttacatat caagaaggta ctcccttagc
    21301 ttcagcagct ttgtcggatg tttctttgac gattgaagat ggctcttata cagctttaat
    21361 tgggcacaca ggtagtggta aatcaactat tttacaactc ttaaatggtt tattggtacc
    21421 aagtcaaggg agtgtgagga tttttgatac cttaatcacc tcgacttcta aaaataaaga
    21481 tattcgtcaa attagaaaac aggttggctt ggtatttcag tttgctgaaa atcagatttt
    21541 tgaagaaacg gttttgaagg acgttgcttt tggaccgcaa aattttggag tttctgaaga
    21601 agatgctgtg aagactgcgc gtgagaaact ggctctggtt ggaattgatg aatcactttt
    21661 tgatcgtagt ccgtttgagc tgtcaggggg acaaatgaga cgtgttgcca ttgcaggcat
    21721 acttgccatg gagccagcta tattagtctt agatgagcca acagctggtc tagatcctct
    21781 agggagaaaa gagttgatga ccctgttcaa aaaactccac cagtcaggga tgaccatcgt
    21841 cttggtaacg catttgatgg atgatgttgc tgaatatgcg aatcaagtct atgtaatgga
    21901 aaagggacgt ttagtaaagg ggggcaaacc aagtgatgtc tttcaagacg ttgtttttat
    21961 ggaagaagtt cagttgggag tacctaaaat tacggccttt tgtaaacgat tggctgatag
    22021 aggcgtgtca tttaaacgat taccgattaa gatagaggag ttcaaggagt cgctaaatgg
    22081 atagtatgat tttggggcgt tatatcccag gggattcgat tgttcaccga ttggatccac
    22141 gtagcaaatt gcttgctatg atgctactga ttttgattgt gttttgggct aataacccct
    22201 tgacgaatct gattcttttt atagcgacag ggatatttat tgccttgtca ggagtatctc
    22261 tttcattttt tattcagggc ttgaagtcta tgtttttctt gattgccttc acaactattt
    22321 ttcaactatt tttcatttct aatgggaatg ttttatttga attttcgttt gtgagaatca
    22381 cggattatgc tttgcaacaa gctgggatta ttttttgtcg ctttgtattg attattttct
    22441 tttcaacttt gttaacctta acaaccatgc ctttaagttt ggcatcagct gtcgaagctt
    22501 tattagcacc tttaaagcgt gtgaaagttc cagttcatga aattggattg atgctgtcta
    22561 tgagtttgcg ttttgtccca accttgatgg atgatacgac tcggattatg aatgcacaga
    22621 aagctcgtgg agtggatttt ggagaaggaa gcatcgttca aaaagtaaag gcgatgattc
    22681 ccattttgat tcctcttttt gcgacaagtt taaaacgtgc agattccttg gctatcgcta
    22741 tggaagcgcg tggctatcag ggtggaaaag gcagaagtca ataccgacaa ttgaaatgga
    22801 ctctgaagga tacgctgacc attcttgtta ttctcgtact tggttgttgt ttatttttct
    22861 taaaatctta gtagctttca ggaattgata aaaagttact gtaacagttt ttgatataaa
    22921 ggtagggata tgaaccgttt taaaaaatca aaatatgtca ttattgtttt tgtcactgtt
    22981 ctgcttgtgt cagctctctt agcgacgact tattcaagta caattgtgac aaaattagga
    23041 gatggaatct cattggttga tagagttgta caaaaacctt ttcagtggtt tgattctgtc
    23101 aaatcagatt tggctcattt gacacgaaca tataatgaaa atgaaagttt gaagaaacag
    23161 ctttaccaat tagaagttaa atcaaatgag gtggaaagtt taaagacaga aaatgaacaa
    23221 ctgcgccaat tgcttgatat gaagtctaaa ttgcaagcca caaagacttt agcagcagat
    23281 gttattatgc gttctccggt atcttggaag caggagttga ccttagatgc aggcagatca
    23341 aaaggtgctt ctgagaacat gttagctatt gcaaatggtg gcttgattgg gagtgtttca
    23401 aaagtagagg agaactctac tatagtcaac cttctgacaa atacggaaaa tgctgataag
    23461 atttctgtta aaattcaaca tggctctact acaatttatg gaattattat tggctatgac
    23521 aaggaaaatg acgttcttaa aattagccaa ttaaatagta atagcgatat tagtgcggga
    23581 gataaggtga ctactggtgg attaggaaac tttaacgttg ctgatattcc tgttggtgaa
    23641 gtggttgcca caacgcatag tacagactat ttgacacgag aagtaactgt taaattgagt
    23701 gcagatactc ataatgtaga tgtgatagaa ttagtgggga attcataatg agacagttga
    23761 agcgagttgg agtattttta ttgcttcctt tctttgttct aattgacgcc catattagcc
    23821 agcttctggg ctcatttttc ccccatgtac atttggctag tcattttctt tttctatttc
    23881 tcttatttga gacgatagaa gtatcagagt atctctacct agtctattgt tttgttatag
    23941 gcttggttta tgatgtttac tttttccatc taatagggat tacaactctc ttatttatct
    24001 tattgggagc cttccttcat aaattgaata gtgttatttt gttgaatcgt tggacaagaa
    24061 tgctagctat gattgtgctg acattcctgt ttgaaatggg tagttatctt ttggctttta
    24121 tggtagggtt gacagtagat agcatgtcga tttttatagt ctatagcttg gtaccgacga
    24181 tgattttaaa ttttttatgg attactgttt ttcaatttat ttttgaaaaa tattatctat
    24241 aagaacgaca tataaatgta acaaaggcgt aatatttatt aggccttttt ttggtatact
    24301 agtattgtct ttaaaagaag gagtatctac gtaatatgaa gaaaaaaatc ttagcgtcac
    24361 ttttattaag tacagtaatg gtttctcaag tagctgtttt aacaactgcg catgcagaaa
    24421 cgactgatga caaaattgct gctcaagata ataaaattag taacttaaca gcacaacaac
    24481 aagaagccca aaaacaagtt gaccaaattc aggagcaagt atcagctatt caagctgagc
    24541 agtctaactt gcaagctgaa aatgatagat tacaagcaga atctaagaaa ctcgagggtg
    24601 agattacaga actttctaaa aacattgttt ctcgtaacca atcgttggaa aaacaagctc
    24661 gtagtgctca aacaaatgga gccgtaacta gctatatcaa taccattgta aactcaaaat
    24721 caattacaga agctatttca cgtgttgctg caatgagtga aatcgtatct gcaaacaaca
    24781 aaatgttaga acaacaaaag gcagataaaa aagctatttc tgaaaaacaa gtagcaaata
    24841 atgatgctat caatactgta attgctaatc aacaaaaatt ggctgatgat gctcaagcat
    24901 tgactacgaa acaggcagaa ctaaaagctg ctgaattaag tcttgctgct gagaaagcga
    24961 cagctgaagg ggaaaaagca agtctattag agcaaaaagc agcagctgag gcagaggctc
    25021 gtgcagctgc ggtagcagaa gcagcttata aagaaaaacg agctagccaa caacaatcag
    25081 tacttgcttc agcaaacact aacttaacag ctcaagtgca agcagtatct gaatctgcag
    25141 cagcacctgt ccgtgcaaaa gttcgtccaa catacagtac aaacgcttca agttatccaa
    25201 ttggagaatg tacatgggga gtaaaaacat tggcaccttg ggctggagac tactggggta
    25261 atggagcaca gtgggctaca agtgcagcag cagcaggttt ccgtacaggt tcaacacctc
    25321 aagttggagc aattgcatgt tggaatgatg gtggatatgg tcacgtagcg gttgttacag
    25381 ctgttgaatc aacaacacgt atccaagtat cagaatcaaa ttatgcaggt aatcgtacaa
    25441 ttggaaatca ccgtggatgg ttcaatccaa caacaacttc tgaaggtttt gttacatata
    25501 tttatgcaga ttaatttaca gagggactcg aatagagccc tcttttcagg ttttaccgtg
    25561 acaatcccta ttaaaaatta tatcaaaata gcttgaaaat attggaaaag tatggtagaa
    25621 tgaaaattgt cgtgtgaacg ataatactca ttcttgatga attgtgaagc agttgccctt
    25681 gggtcgtttt gcgagttgaa gtcaagaaga ggaaaaaaac aaaaaggaga aatactcatg
    25741 gcagtaattt caatgaaaca acttcttgag gctggtgtac actttggtca ccaaactcgt
    25801 cgctggaatc ctaagatggc taagtacatc tttactgaac gtaacggaat ccacgttatc
    25861 gacttgcaac aaactgtaaa atacgctgac caagcatacg acttcatgcg tgatgcagca
    25921 gctaacgatg cagttgtatt gttcgttggt actaagaaac aagcagctga tgcagttgct
    25981 gaagaagcag tacgttcagg tcaatacttc atcaaccacc gttggttggg tggaactctt
    26041 acaaactggg gaacaatcca aaaacgtatc gctcgtttga aagaaattaa acgtatggaa
    26101 gaagatggaa ctttcgaagt tcttcctaag aaagaagttg cacttcttaa caaacaacgt
    26161 gcgcgtcttg aaaaattctt gggcggtatc gaagatatgc ctcgtatccc agatgtgatg
    26221 tacgtagttg acccacataa agagcaaatc gctgttaaag aagctaaaaa attgggaatc
    26281 ccagttgtag cgatggttga caccaatact gatccagatg atatcgatgt aatcatccca
    26341 gctaacgatg acgctatccg tgctgttaaa ttgatcacag ctaaattggc tgacgctatt
    26401 atcgaaggac gtcaaggtga ggatgcagta gcagttgaag cagaatttgc agctttagaa
    26461 actcaagcag attcaattga agaaatcgtt gaagttgtag aaggcgacaa cgcttaattt
    26521 atacaaatag taattaccta ggagggcggg gcttagcccg gctctcctat tttcaaaaaa
    26581 tataggagaa ttaaaatggc agaaattaca gctaaacttg taaaagagtt gcgtgaaaaa
    26641 tctggtgccg gtgttatgga cgctaaaaaa gcgcttgtag aaacagacgg tgacatcgaa
    26701 aaagcgattg aattgcttcg tgaaaaaggt atggctaagg cagctaagaa agctgaccgt
    26761 gttgctgcag aaggtttgac tggtgtttat gttaacggta atgttgcagc agttattgaa
    26821 gtaaacgctg aaactgactt cgttgcaaaa aacgctcaat tcgttgaatt ggtaaatact
    26881 acagctaaag tcattgctga aggaaaacct gctaacaacg aagaagctct tgctttgata
    26941 atgccttcag gtgaaactct tgaagctgca tacgtatctg caacagcaac tatcggagag
    27001 aaaatctcat tccgtcgctt tgcattgatt gaaaaaacag acgcacaaca ctttggagca
    27061 taccaacata acggtggacg tatcggtgtt atttcagttg ttgaaggtgg agacgaagca
    27121 cttgctaaac aattgtcaat gcacatcgca gcgatgaaac caacagttct ttcttacaaa
    27181 gaattggatg agcaattcgt taaagatgag ttggcacaat tgaatcacgt tatcgaccaa
    27241 gacaacgaaa gccgtgcaat ggttaataaa ccagctcttc cacacttgaa gtatggatca
    27301 aaagctcaat taactgatga tgttattgct caagctgaag ctgacatcaa agctgaattg
    27361 gctgcagaag gcaaaccaga aaaaatctgg gacaaaatta ttccaggtaa aatggatcgc
    27421 ttcatgcttg ataacactaa agttgaccaa gcttacacac ttcttgcaca agtttacatc
    27481 atggatgaca gcaagacagt tgaagcatac cttgaatcag ttaacgcttc ggtagttgag
    27541 tttgctcgct ttgaagttgg tgaaggtatc gagaaagctg caaacgactt cgaagctgaa
    27601 gttgcagcta caatggcagc agccttgaat aactaataat agaaaggaag caaattgctt
    27661 ccttttttgt atagggctta gatttttcct gaaattgttt tttccccagt ctcactcgat
    27721 tagaataatt aaaacaaaaa gccctataat aagggctaag tgcatttagg agactatact
    27781 tcaaattcat agtaagcgcg tcataacaag gtatctatcc taattcccca acttccagta
    27841 tactagataa aaaataatta tcggaggaaa ggtattgtac tatgataatt caactaagtg
    27901 atttaggtca agttcacctt gtttgtggca agacagatat gaggcaggga atagactcat
    27961 tagcctatgt agttaaaacc cactttgaat tggattcttt ctccggtcaa gtctttctct
    28021 tttgtggtgg acgtaaagac cgctttaaag ccctttactg ggatggtcaa ggattttggc
    28081 tactatataa acgctttgag aacggaaaac tgacttggct aagtacagaa aaggatgtca
    28141 aagctctcgc acctgaacaa gtagactagc ttatgaaggg cttttctatc actccaaaaa
    28201 tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt agaaatcgat
    28261 ttgactgtcc tgatcgattt gtcctgttct tatttcattt tactataaat ccatcagaaa
    28321 gtcgtgattt ctattgaaat gaggactttc tttttacact catctgcttt caaaaagcat
    28381 tctagtccgt ctccgattaa cgatggactt tatcacctcc ttctccagtc cttgtatgac
    28441 atcttccaaa gttcgaaagg ctttattctt aaatccacgt ttacgaatct ctttccacac
    28501 ttgttcaatg gggttcatct ctggtgtgta tggaggaata aatgaaaagc caatattagt
    28561 cggaatcttt aaggtacttg atttatgcca tatagcattg tccataacga gtaaaagata
    28621 atcatctgga taagcttgtg aaagctccta ttcctaaagc ccctttagcg cataactttg
    28681 gctcagcttc tattatcgct cacaccatcc atcagaagtt taatctgaag gtacccaatt
    28741 atcgccaaga agaaggttgg gctaggatgg gtttaccaat cacacgtaag gaaattgtta
    28801 attggcatat caaggcgagt caatactatt tggagcccct ttataacctc ttgcgagaga
    28861 gactattgac gcagtcctta cttcatgcgg atgaaacttc ttatagggtg ctagagagtg
    28921 atagtcagct gacttactat tggacttttt tgtctgggaa agctgagaaa caagggatta
    28981 cgctttacca tcatgtccta atcgatttgt tcatatctta tttcaatcca ttataaatag
    29041 tgagaaatat ctatcctatc ttctagaatg tcttccaaac gtggaaactc tcgtaaacaa
    29101 agaggtttta gaggcctatt taccatggac taaagttgta caagaaaagt gcaaataaga
    29161 aatctccaga ttaggaacta tccgtgagtt ctctagtctg gagatttttc aatagacttc
    29221 gttattggat ggttacaatt cataaagtgc tgtagagaga taacgttcac cgttatctgg
    29281 tgctagggca aggacttttt tacctgtacc taattttttg gcaacctcaa tggctccgta
    29341 gatagctgca gctgaggaaa tccctacaag gaagccttct tttccaccaa tttcacgtcc
    29401 gagtgcaaga gcgtcatctg atgttacacg aacgatacca tcataggctt tagtatcaag
    29461 tgtatcagga ataaatccag ctgagatacc ttgaattttg tgaggaccag gtttttcacc
    29521 agatagaata gcagattcat ctgcttctac tgcaaaaact tgaatgttag aattttctga
    29581 tttgagtgca tgagaaacac cagaaatcgt tccaccggta cctactccag caacaaaggc
    29641 atctaatcca tctttaccga aagcagctag tatctcagct cctgttgttc tttcgtgtac
    29701 ttctggatta gctggattgt caaattgaag aggaaggaaa ccatcacgtt cagcagcgat
    29761 ttcttgagcc ttagcaatag cacctttcat tccctcgcta ccaggagtta ggacgagttc
    29821 agcaccataa gcttggataa ttttacgtcg ttctacactc atagtttcag gcataacgat
    29881 gacgacttta taccctttag cagcacctac ccatgaaagt ccaataccag tgtttccact
    29941 tgttgcttca acaatagtag aaccaggttt cagaatacca tcttgttcag ctttttcaat
    30001 catgctaagg gcaatacggt cttttacaga tgaaccagga ttaaatgctt caagctttat
    30061 atagacgtct gcagcacctt ctggcacgat gttgttaagt ttaacaatcg gtgtttgacc
    30121 gattaattca gtaatgttgt tataaataga catatgaata cctctttgta taagatatct
    30181 ttagtataac gctatccata ccatttgtaa aatatagaaa tcctatcgaa gcgataggat
    30241 ttctatatat catagatcaa agtcattaat tttcaagtga ttgcgttcag ctaattctag
    30301 taaataggtg tgaaggaaaa cgatatcagg tttcgtttga attgcttcat tttctagtat
    30361 attttggtac gcatcttttt attttgctcg ctaaagtagt tgtgagaatg tcaacgaaac
    30421 gctgtattat tcattgttta cactaagttt acaggaactt caacctctcg taaaccttgg
    30481 tcagttaaag tgacttttcc attaaaaaac tccacaagtg cagctttaat agtttctttt
    30541 tcttctttat caacataaat catcgtatcg acttgatctg taaagtttgt atccagctcc
    30601 atgagatcat gttctttaag gaagttactg tactcttggt actgagcata agacatttga
    30661 atagcaatgc cagcctgttc ttttatttca ataataccaa tttctttgac agctaaggcg
    30721 acactgccgg cgtaagcacg aattagtcct ccagcgccta gtttaatacc accaaagtag
    30781 cgtgtcacga ccacacagac attggtgaga ttgtgatttt ctagtacccc aagcatggga
    30841 acaccagcag taccactagg ctcaccatca tcacttgtac gtttaatttc actacgttct
    30901 ccaataataa aggcagagca gttatgtgtc gctttgtagt gttctttttt gatggcagta
    30961 atgaagtcac gagcctcttc ttcgctataa acacgcttgg catggcagat aaagcgagat
    31021 tttttgattt cttcttggac ttgaccgtcc tctttaattg tcctaaattc catgatttaa
    31081 ttgtactaaa aaatcatcta aagtgctagt ttttacgaat aaagaagtat gaaagtaaat
    31141 ttagattatc tcggtcgttt atttactgag aatgaattaa cagaagaaga acgtcagttg
    31201 gcggagaaac ttccagcaat gagaaaggag aaggggaaac ttttctgtca acgctgtaat
    31261 agtactattc tagaagaatg gtatttgccc atcggtgctt actattgtcg agagtgcttg
    31321 ctgatgaagc gagtcagaag tgatcaaact ttatactatt ttccgcagga ggattttcca
    31381 aagcaagatg ttctcaaatg gcgcggccaa ttaactcctt ttcaagagaa ggtgtcagag
    31441 ggattgcttc aagtagtaga caagcaaaag ccaaccttag ttcatgcggt aacaggagct
    31501 ggaaagacag aaatgattta tcaagtagtg gctaaagtga tcaatgcggg tggtgcagtg
    31561 tgtttggcta gtcctcgcat agatgtttgt ttggatctgt acaagcgcct gcaacaggat
    31621 ttttcttgcg ggatagcttt gctacatgga gaatcggaac cttattttcg aacaccacta
    31681 gttgttgcaa caacccatca gttattgaag ttttatcaag cttttgattt gctgatagtg
    31741 gatgaagtag atgcttttcc ttatgttgat aatcccatgc tttaccacgc tgtcaagaat
    31801 agtgtaaagg agaatggatt gagaatcttt ttaacagcga cttcgaccaa tgagttagat
    31861 aaaaaggtcc gtttaggaga actaaaaaga ctgaatttac cgagacggtt tcatggaaat
    31921 ccgttgatta ttccaaaacc aatttggtta tcggatttta atcgctactt agacaagaat
    31981 cgtttgtcac caaagttaaa gtcctatatt gagaagcaga gaaagacagc ttatccgtta
    32041 ctcatttttg cttcagaaat taagaaaggg gagcagttag cagaaatctt acaggagcaa
    32101 tttccaaatg agaaaattgg ctttgtatct tctgtaacag aggatcgatt agagcaagta
    32161 caagcttttc gagatggaga actgacaata cttatcagta cgacaatctt ggagcgtgga
    32221 gttaccttcc cttgtgtgga tgttttcgta gtagaggcca atcatcgttt gtttaccaag
    32281 tctagtttga ttcagattgg tggacgagtt ggacgaagca tggatagacc gacaggagat
    32341 ttgcttttct tccatgatgg gttaaatgct tcaatcaaga aggcgattaa ggaaattcag
    32401 atgatgaata aggaggctgg tctatgaagt gcttgttatg tgggcagact atgaagactg
    32461 ttttaacttt tagtagtctc ttacttctga ggaatgatga ctcttgtctt tgttcagact
    32521 gtgattctac ttttgaaaga attggggaag agaactgtcc aaattgtatg aaaacagagt
    32581 tgtcaacaaa gtgtcaagat tgtcaacttt ggtgtaaaga gggagttgaa gtcagtcata
    32641 gagcgatttt tacttacaat caagctatga aggatttttt cagtcggtat aagtttgatg
    32701 gagacttcct gttaagaaaa gttttcgctt catttttaag tgaggagttg aaaaagtaca
    32761 aagagtatca atttgttgta attcccctaa gtcctgatag atatgctaat agaggattta
    32821 atcaggttga gggcttggta gaggcagcag gctttgagta tctggattta ttagagaaaa
    32881 gagaagagag agccagttct tctaaaaatc gttcagagcg cttggggaca gaacttcctt
    32941 tctttattaa aagtggagtc actattccta aaaaaatcct acttatagat gatatctata
    33001 ctacaggagc aactataaat cgtgttaaga aactgttgga agaagctggt gctaaggatg
    33061 taaaaacatt ttcccttgta agatgaggaa aaaatttgca aaaacagaat gaaagcgtta
    33121 taataaaatc ataaaaacaa aaatgtttag aaagaaggta ctcatatgat taaatatagt
    33181 atccgtggtg aaaacctaga agtaacagaa gcaattcgtg attatgtagt ttctaaactc
    33241 gaaaagatcg aaaagtactt ccaaccagaa caagagttgg atgcccgaat taacttaaaa
    33301 gtttatcgtg aaaaaacggc taaagtggaa gtaacgattc cgcttggatc tattactctc
    33361 cgcgcagaag atgtatctca agatatgtat ggttcaattg accttgtaac tgataaaatt
    33421 gaacgtcaga ttcgtaaaaa taaaacaaaa atcgagcgta aaaataaaaa taaggtagca
    33481 actggtcaat tatttacaga tgctttggtg gaagattcaa atgttgtcca gtctaaagtt
    33541 gttcgttcaa aacaaattga tttaaaacca atggatttgg aagaagcaat tctacaaatg
    33601 gatttattgg ggcatgattt ctttatctat gtggatgttg aagatcagac aaccaatgtg
    33661 atttatcgtc gtgaggatgg cgaaattggt ttgttagagg ttaaagaatc ttaatttcaa
    33721 tatgtgtaaa ggtaggttta ctgaattgta aactaccttt ttcttataat tgatagaatt
    33781 actgattaca cttttaaaaa gtcgcttttt gaggggtatt atggtataat gggtgccaag
    33841 aggttttgaa tgaaaaaatt ttatgtaagt ccaatttttc ctattctagt aggattgatt
    33901 gcgtttggag tcttatccac tttcattatt tttgttaata ataatctgtt gacggtttta
    33961 attttgtttc tttttgtagg aggctatgtt tttttattta agaaactgag agtgcattat
    34021 acaaggagtg atgtagaaca gatacagtat gtaaaccacc aagcggaaga aagtttgaca
    34081 tctctattgg aacaaatgcc tgtaggtgtt atgaaattga atttatcttc tggagaggtt
    34141 gagtggttta atccctatgc tgaattgatt ttgaccaagg aagatggtga ttttgattta
    34201 gaagctgttc aaacgattat caaggcttca gtaggaaatc cgtctactta tgccaagctt
    34261 ggtgagaagc gttatgctgt tcatatggat gcttcttccg gtgttttgta ttttgtagat
    34321 gtatccaggg aacaagccat aacagatgaa ttggtaacaa gtcgaccagt gattgggatt
    34381 gtctctgtgg ataattatga tgatttggag gatgcaactt ctgagtcaga tattagtcaa
    34441 atcaatagtt ttgtagctaa ttttatatca gagttttcag aaaaatacat gatgttttct
    34501 cgtcgggtaa gtatggatcg attttatcta tttactgact acacggtgct tgagggcttg
    34561 atgaatgata aattttctgt tattgatact ttcagagaag agtcgaaaca gagacagttg
    34621 cccttgacct taagtatggg attttcttat ggcgatggaa atcatgatga gatagggaaa
    34681 gttgctttgc tcaatttgaa cttggctgaa gtacgtggtg gcgaccaggt ggttgttaag
    34741 gaaaacgacg aaacgaaaaa tccagtttat tttggtggtg ggtctgctgc ttcaatcaag
    34801 cgtacacgga ctcgtacgcg cgctatgatg acagctattt cagataagat tcggagtgta
    34861 gatcatgttt ttgtagtcgg tcacaaaaat ttagacatgg atgctttggg ctctgctgta
    34921 ggtatgcagt tgttcgccag caatgtgatt gaaaatagct atgctcttta tgatgaagaa
    34981 caaatgtctc cagatattga acgagctgtt tcattcatag aaaaagaagg agttacgaag
    35041 ttgttgtctg ttaaggatgc aatggggatg gtgaccaatc gttctttgtt gattcttgta
    35101 gaccattcaa agacagcctt aacattatca aaagaatttt atgatttatt tacccaaacc
    35161 attgttattg accaccatag aagggatcag gattttccag ataatgcggt tattacttat
    35221 atcgaaagtg gtgcaagtag tgccagtgag ttggtaacgg aattgattca gttccagaat
    35281 tctaagaaaa atcgtttgag tcgtatgcaa gcaagtgtct tgatggctgg tatgatgttg
    35341 gatactaaaa atttcacctc gcgagtaact agtcggacat ttgatgttgc tagctatctc
    35401 agaacgcgcg gaagtgatag tattgctatc caggaaatcg ctgcgacaga ttttgaagaa
    35461 tatcgtgagg tcaatgaact tattttacag gggcgtaaat taggttcaga tgtactaata
    35521 gcagaggcta aggacacgaa atgctatgat acagttgtta ttagtaaggc agcagatgcc
    35581 atgttagcca tgtcaggtat tgaagcgagt tttgttcttg cgaagaatac acaaggattt
    35641 atctctatct cagctcgaag tcgtagtaaa ctgaatgtac aacggattat ggaagagtta
    35701 ggcggtggag gccactttaa tttggcagca gctcaaatta aagatgtaac cttgtcagaa
    35761 gcaggtgaaa aactgacaga aattgtatta aatgaaataa aggaaaagga gaaagaagaa
    35821 tgaaagtaat ctttttagca gatgttaaag gaaaaggtaa aaaaggcgaa attaaggaag
    35881 taccaacagg gtatgcgcaa aactttctta tcaaaaagaa tctagccaaa gaagcgactg
    35941 ctcaagctgt aggtgaactt cgtggtaaac aaaaatcgga agaaaaagct cacgctgaga
    36001 tgattgcaga agggaaagca attaaagcac aacttgaagc agaagaaact gttgtagaat
    36061 ttgttgaaaa agttggtcca gatggtcgta cctttggttc tattaccaat aagaagattg
    36121 cagaagaatt acaaaagcaa tttggaatta agattgataa acgtcatatt caagtacaag
    36181 ctccgattcg agcggttggt ttgattgatg tgccagtgaa aatctatcaa gatatcacaa
    36241 gtgtaatcaa tcttcgtgtg aaagaaggat aagtttacac cttcttgaca agattgtaaa
    36301 aggaagggaa gtctgatggc agaagtagaa gagttacgag tacaacctca agatatctta
    36361 gctgagcaat ccgttttagg ggctatcttt attgatgaga gtaaacttgt ttttgtgcga
    36421 gaatacattg agtctcggga cttttttaag tatgcccatc gtttgatttt ccaagccatg
    36481 gtcgatttat ccgatcgtgg tgatgccata gatgcaacaa cggttcgtac tatccttgat
    36541 aatcaaggtg atttacagaa tattggtggc ttgtcttact tggttgagat tgtcaattct
    36601 gtgccaactt ctgctaatgc ggagtattat gctaagattg ttgcagaaaa agcaatgcta
    36661 cgtcgtttaa ttgccaagtt gacagagtct gtcaaccaag cttacgaagc gtcacaacca
    36721 gctgatgaaa ttattgctca ggcagaaaaa gggctgattg atgtcagtga aaatgcaaat
    36781 cgaagcgggt ttaagaacat tcgagatgtg ttgaatctca actttggaaa tctggaagct
    36841 cgctcgcaac aaacgaccga tattacaggt attgcgacag gttatcgtga tttggatcat
    36901 atgacaacag gacttcatga ggaggagttg attatcttag cagctcgtcc agcagttggt
    36961 aagacagcat ttgccttgaa tatcgctcag aatattggga ctaagttgga caaaacggtt
    37021 gctatttttt cactcgaaat gggtgcggaa agcttggtag accgtatgtt agctgcagaa
    37081 ggcttggtgg agtcacattc tatccgtaca gggcaattga cagatgagga gtggcaaaaa
    37141 tatactattg ctcagggtaa tctagctaac gccagtatct atatcgatga tacgccaggt
    37201 attcggatta cagagattcg ttctcgttct cgtaaattgg ctcaagaaac tggaaatctt
    37261 ggtttgattt tgatagacta tttgcaactt atcacgggaa ctggtcgaga aaatcgtcaa
    37321 caagaagttt ctgaaatttc tcgtcagttg aaaatactag ccaaggaatt gaaggttcca
    37381 gtaatcgctc tgagtcagct ttctcgtggt gtagaacaac gtcaggacaa gagaccggtc
    37441 ttgtctgata ttcgtgaatc tgggtctatt gagcaggacg ctgatatcgt agcttttctc
    37501 tatcgcgatg actactatga acgtggtggt gaagaagagg agggtatccc aaataataag
    37561 gtggaagtta ttatcgagaa aaaccgtagt ggagctcgtg gaacagtgga attgattttc
    37621 caaaaagaat acaataaatt ttcaagtatc tcaaagaggg aggcataaga tgtcagatgc
    37681 atttacagat gtagccaaga tgaaaaaaat caaagaagaa atcaaggcac atgagggaca
    37741 agtcgtagaa atgactttgg agaatggtcg taagcgccaa aaaaatagat tgggtaagct
    37801 aattgaagtt tatccatccc tatttattgt ggagtttggg gatgtggaag gagataaaca
    37861 agttaatgtt tacgttgaat cctttactta ctcagatatt cttacagaaa agaatttgat
    37921 tcattatctt gactaaagtg agaaattttc tcactttttc ttttttctcc gaataattta
    37981 ggtgaaggca atcatcgctt tatattattt tttaaggagg aagaatgaaa attttaccgt
    38041 ttatagcaag aggaacaagt tattacttga agatgtcagt taaaaagctt gttccttttt
    38101 tagtagtagg attgatgcta gcagctggtg atagtgtcta tgcctattcc ggaggaaatg
    38161 gatcgattgc gcgtggggat gattatcctg cttattataa aaatgggagc caggagattg
    38221 atcagtggcg catgtattct cgtcagtgta cttcttttgt agcctttcgt ttgagtaatg
    38281 tcaatggttt tgaaattccg gcagcttatg gaaatgcgaa tgaatgggga catcgtgctc
    38341 gtcgggaagg ttatcgtgta gataatacac cgacgattgg ttccattact tggtctactg
    38401 caggaactta tggtcatgtt gcctgggtgt caaatgtaat gggagatcag attgagattg
    38461 aggaatataa ctatggttat acagaatcct ataataaacg aattataaaa gcaaacacga
    38521 tgacaggatt tattcatttt aaagatttgg atggtggcag tgttgggaat agtcaatcct
    38581 caacttcaac aggcggaact cattatttta agaccaagtc tgctattaaa actgaacccc
    38641 tagttagtgc aactgtgatt gattactatt atcctggaga gaaggttcat tatgatcaaa
    38701 ttctcgaaaa agacggctac aagtggttga gttatactgc ctataatgga agctatcgtt
    38761 atgttcaatt ggaggctgtg aataaaaatc ctctaggtaa ttctgttctt tcttcaacag
    38821 gtggaactca ttattttaag accaagtctg ctatcaaaac tgaaccccta gttagtgcaa
    38881 ctgtgattga ttactattat cctggggaga aggttcatta tgatcagata cttgaaaaag
    38941 acggctacaa gtggttgagt tatacggctt ataacggaag tcgtcgctat atacagctag
    39001 agggagtgac ttcttcacaa aattatcaga atcaatcagg aaatatctct agctatggat
    39061 ccaataatag ttcaactgtc ggttggaaga aaataaatgg tagttggtat catttcaaat
    39121 caaatggttc taaatcaaca ggatggctga aagatggttc tagctggtat tatttgaaat
    39181 tatctggtga aatgcagaca ggatggttaa aggagaatgg ctcgtggtat tatctgggta
    39241 gttcaggggc aatgaaaaca ggctggtacc aggtctctgg taagtggtat tattcttact
    39301 cttcaggcgc cttagctgtt aatacgacgg tggatggcta cagagtaaac agtgatggag
    39361 aacgagtata gaaaattgga gtaggagaaa tttcctgctc ttttctgtaa gcagtttcct
    39421 tgacattttt cttattttgc gctatcatat atacatataa tatatgggag tctgtgtaca
    39481 gtctgagagg aagtgttaaa cttcgaccgc acctgatctg ggtaatgcca gcggagggaa
    39541 cgatacttag tctaattttg caccttttcc atgtatggta aaggtttttc ttttttttaa
    39601 aaggaaaacg agaagaggag gttcttatga aagcaagcat tgccttgcaa gttttacccc
    39661 tagtacaggg gattgatcgg atagctgtta ttgatcaggt cattgcttat ctgcaaactc
    39721 aagaagtgcc gatggtagtg acaccatttg aaacggtctt ggaaggggag tttgatgagc
    39781 ttatgcgcat tctaaaagaa gcgctggaag tggcagggca ggaggcagac aatgtctttg
    39841 ccaatgtcaa aataaatgta ggagagattt taagtattga tgagaaactt gagaagtata
    39901 ctgagacgac acattagtct attgggcttt ctcggagtct tgtcaatctg gcagttagca
    39961 ggttttctta aactgctccc caagtttatc ctgccgacac ctcttgaaat tctccagccc
    40021 tttgttcgtg acagagaatt tctctggcac catagctggg cgaccttgag agtggcttta
    40081 ctggggctga ttttgggagt tttgattgcc tgtcttatgg ctgtactcat ggatagtttg
    40141 acttggctca atgacctgat ttaccctatg atggtggtca ttcagaccat tccgaccatt
    40201 gccatagctc ctatcctggt cttgtggcta ggttatggga ttttgcccaa gattgtcttg
    40261 attatcttaa cgacaacctt tcccatcatc gtcagcattt tggacggttt taggcattgc
    40321 gacaaggata tgctgacttt gtttagtctg atgcgggcca agccttggca aatcctgtgg
    40381 cattttaaaa ttccagtcag cctgccctac ttttatgctg gtctgagggt cagtgtctcc
    40441 tacgctttta tcacaacagt ggtatctgag tggttgggag gctttgaggg gcttggtgtt
    40501 tatatgattc agtccaagaa attgtttcag tatgatacca tgtttgccat tattattctg
    40561 gtgtcgatta tcagtctttt gggtatgaag ctggtcgata tcagtgaaaa atatgtgatt
    40621 aaatggaaac gtacttaaaa tagagcgttt ttgaaaaaga aaagaggaaa tcaaaatgaa
    40681 gaaaacatgg aaagtgtttt taacgcttgt aacagctctt gtagctgttg tgcttgtggc
    40741 ctgtggtcaa ggaactgctt ctaaagacaa caaagaggca gaacttaaga aggttgactt
    40801 tatcctagac tggacaccaa ataccaacca cacagggctt tatgttgcca aggaaaaagg
    40861 ttatttcaaa gaagctggag tggatgttga tttgaaattg ccaccagaag aaagttcttc
    40921 tgacttggtt atcaacggaa aggcaccatt tgcagtgtat ttccaagact acatggctaa
    40981 gaaattggaa aaaggagcag gaatcactgc cgttgcagct attgttgaac acaatacatc
    41041 aggaatcatc tctcgtaaat ctgataatgt aagcagtcca aaagacttgg ttggtaagaa
    41101 atatgggaca tggaatgacc caactgaact tgctatgttg aaaaccttgg tagaatctca
    41161 aggtggagac tttgagaagg ttgaaaaagt accaaataac gactcaaact caatcacacc
    41221 gattgccaat ggcgtctttg atactgcttg gatttactac ggttgggatg gtatccttgc
    41281 taaatctcaa ggtgtagatg ctaacttcat gtacttgaaa gactatgtca aggagtttga
    41341 ctactattca ccagttatca tcgcaaacaa cgactatctg aaagataaca aagaagaagc
    41401 tcgcaaagtc atccaagcca tcaaaaaagg ctaccaatat gccatggaac atccagaaga
    41461 agctgcagat attctcatca agaatgcacc tgaactcaag gaaaaacgtg actttgtcat
    41521 tgaatctcaa aaatacttgt caaaagaata cgcaagcgac aaggaaaaat ggggtcaatt
    41581 tgacgcagct cgctggaatg ctttctacaa atgggataaa gaaaatggta tccttaaaga
    41641 agacttgaca gacaaaggct tcaccaacga atttgtgaaa taatgacaga aattagacta
    41701 gagcacgtca gttatgccta tggtcaggag aggattttag aggatatcaa cctacaggtg
    41761 acttcaggcg aagtggtttc catcctaggc ccaagtggtg ttggaaagac caccctcttt
    41821 aatctaatcg ctgggatttt agaagttcag tcagggagaa ttgtccttga tggtgaagaa
    41881 aatcccaagg ggcgcgtgag ttatatgttg caaaaggatc tgctcttgga gcacaagacg
    41941 gtgcttggaa atatcattct gcccctcttg attcaaaagg tggataaggc agaagctatt
    42001 tcccgagcgg ataaaattct tgcgaccttc cagctgacag ctgtaagaga caagtatcct
    42061 catgaactta gcggtgggat gcgccagcgt gtagccttac tccggaccta cctttttggg
    42121 cacaagctct ttctcttaga tgaggccttt agcgccttgg atgagatgac aaagatggaa
    42181 ctccacgctt ggtatcttga gattcacaag cagttgcagc taacaaccct gatcatcacg
    42241 catagtattg aggaggccct caatctcagc gaccgcatct atatcttgaa aaatcgccct
    42301 gggcagattg tttcagaaat taaactagat tggtctgaag atgaggacaa ggaagtccaa
    42361 aagattgcct acaaacgtca aattttggcg gaattaggct tagataagta gaaaaatagg
    42421 gagttggtga agattatcct ttaccagcgc cctttttctt ttaaaaatga gaaaatttcg
    42481 gtataatagt caaacaaggt caaggtttaa agagagaggt gggtttgtta tgagatttaa
    42541 aaatacatcg gatcatattg aggcctacat caaggcgatt ttagatcaat ctggtatcgt
    42601 ggagttgcaa cggagtcagt tggcagatac ctttcaggtt gttcctagtc agattaacta
    42661 cgtgatcaag acacgcttta cggaaagtag aggctacttg gttgaaagta agcgtggtgg
    42721 cggaggctac attcgtatag gacggattga gttttctagt catcatgaaa tgctccggga
    42781 gctgctttac tcgattggtg agcgagtcag tcaagaaatt tatgaggata ttctccagct
    42841 tttggttgag caggaattga tgaccaagca ggagatgaat ttgctagaat cagtagcttt
    42901 ggatcgcgtt ttaggagaag aagctccagt tgttcgagca aacatgctac gtcagatcat
    42961 acaagaggta gatagaaaag ggaagtaaga tgaactattc aaaagcattg aatgaatgta
    43021 tcgaaagtgc ctacatggtt gctggacatt ttggagctcg ttatctagag tcttggcact
    43081 tgttgattgc catgtctaat cacagttata gtgtagcagg ggcaacttta aatgattatc
    43141 cgtatgagat ggaccgttta gaagaggtgg ctttggaact gactgaaacg gactatagcc
    43201 aggatgaaac ctttacggaa ttgccgttct cccgtcgttt gcaggttctt tttgacgaag
    43261 cagagtatgt agcgtcagtg gtccatgcta aggtgctagg gacagagcac gtcttctatg
    43321 cgattttgca tgatggcaat gccttggcaa ctcgtatctt ggagagggct ggtttttctt
    43381 atgaagacaa gaaagatcag gtcaagattg ctgctcttcg tcgaaattta gaagaacggg
    43441 caggctggac tcgtgaagat ctcaaggctt tacgccaacg ccatcgtaca gtagctgaca
    43501 agcaaaattc tatggccaat atgatgggca tgccgcagac tcctagtggt ggtctcgagg
    43561 actatacgca tgatttgaca gagcaagcgc gttctggcaa gttagaacca gtcatcggtc
    43621 gggacaagga aatctcacgt atgattcaaa tcttgagccg gaagactaag aacaaccctg
    43681 tcttggttgg ggatgctggt gtcgggaaaa cagctctggc gcttggtctt gctcagcgta
    43741 ttgctagtgg tgacgtgcct gcggaaatgg ctaagatgcg cgtgttagaa cttgatttga
    43801 tgaatgtcgt tgcagggaca cgcttccgtg gtgactttga agaacgcatg aataatatca
    43861 tcaaggatat tgaagaagat ggccaagtca tcctctttat cgatgaactc cacaccatca
    43921 tgggttctgg tagcggaatt gattcgactc tggatgcggc caatatcttg aaaccagcct
    43981 tggcgcgtgg aactttgaga acggttggtg ccaccactca ggaagaatat caaaaacata
    44041 tcgaaaaaga tgcggcactt tctcgtcgtt tcgctaaagt gacgattgaa gaaccaagtg
    44101 tggcagatag tatgactatt ttacaaggtt tgaaggcgac ttatgagaaa catcaccgtg
    44161 tacaaatcac agatgaagcg gttgaaacag cggttaagat ggctcatcgt tatttaacca
    44221 gtcgtcactt gccagactct gctatcgatc tcttggatga ggcggcagca acagtgcaaa
    44281 ataaatcaaa gcatgtaaaa gcagacgatt ctgacttgag tccagctgac aaggccttga
    44341 tggatggcaa gtggaaacag gcagcccagc taatcgcaaa agaagaggaa gtgcctgtct
    44401 ataaagactt ggtgacagag tctgatattt tgaccacctt gagtcgcttg tcaggaatcc
    44461 cagttcaaaa actgactcaa acggatgcta agaagtattt aaatcttgaa gcagaactcc
    44521 ataaacgggt tatcggtcaa gatcaagctg tttcaagtat tagtcgtgcc attcgccgca
    44581 atcagtcagg aattcgcagt cacaagcgtc cgatcggttc ctttatgttc ctaggaccca
    44641 caggtgtcgg taagaccgag ttggccaagg ctttggcaga agttctcttt gatgacgaat
    44701 cagcccttat ccgctttgat atgagtgagt atatggagaa attcgcagcc agccgtctaa
    44761 atggagctcc tccaggctat gtgggttacg aagaaggtgg ggagttgaca gagaaggttc
    44821 gcaataaacc ctattccgtt ctcctctttg atgaggtaga gaaggcccat ccagatatct
    44881 ttaatgttct cttgcaggtt ctggatgacg gtgtcttgac agatagcaag ggacgcaagg
    44941 tcgatttttc aaataccatt atcattatga catcgaactt aggtgcgact gcccttcgtg
    45001 atgataagac tgttggtttt ggggctaagg atattcgttt tgaccaggaa aatatggaaa
    45061 aacgcatgtt tgaagaactg aaaaaagctt atagaccgga attcatcaac cgtattgatg
    45121 agaaggtggt cttccatagc ctatctagtg accatatgca ggaagtggtg aagattatgg
    45181 tcaagctttt agtggcaagt ttggctgaaa aaggcattga cttgaaatta caagcttcag
    45241 ctctgaaatt gttagcaaat caaggatatg acccagagat gggagctcgc ccacttcgca
    45301 gaaccctgca aacagaagtg gaggacaagt tggcagaact tcttctcaag ggagatttag
    45361 tggcaggcag cacacttaag attggtgtca aagcaggcca gttaaaattt gatattgcat
    45421 aaaagaataa aagtatcagc atctgaccat aagtcacagt ggagtgaaac tcaatgaaaa
    45481 tcaaagagca aactaggcag ctagccgcag gttgctcaaa acactgtttt gaggttgcag
    45541 atagagctga cgtggtttga agagattttc gaagagtatg aaactaaaac ctatagcttc
    45601 taaacgatcc gtggttttca ccattcaaca caaaattcat atgtttatta ccctccgtcg
    45661 tatttgtctt agagcgtgtg tagtagaaaa agagcagtct tatctgaaat ttttattctt
    45721 tcaaaagaga cctgtttctt ttttgcatgt caaatccgtt ctagctggta tttgaaaaat
    45781 caaactaata ctcaatgaaa atcaaagaac aaactaggaa gctagccgca ggttgctcaa
    45841 aacactgttt tgaggttgta gatagagctg acgtagtttg aagagatttt cgaagagtat
    45901 aagctgcaag atgaatgatt ttcttgtatt gacgttgttg ttgacaaaaa gtagcggata
    45961 aatgaaatcc attccattat catagatgat aggctggtag gaaattttca aatagcatac
    46021 aggaaataga tgtatggagt tctggtagta gaaagggaga gagatgaaca ttttagttgc
    46081 agatgacgag gaaatgatta gagaaggaat tgcagcattt ctgacagaag agggttatca
    46141 tgtcattatg gctaaggatg gacaagaggt cttggaaaaa tttcaagatc tccctatcca
    46201 tctcatggta ctggatttaa tgatgcctag gaagagtggt tttgaagtgt taaaagaaat
    46261 caatcaaaag cacgatattc ctgtcatcgt cttgagtgct ctgggagatg aaactactca
    46321 gtcacaggta tttgatctct atgctgatga tcatgtgaca aaaccttttt ctttggtact
    46381 gcttgtcaag cgtattaagg cgcttatcag acgttactac gtcatagagg atctttggcg
    46441 atatcaggat gtaacagtgg attttacctc ttacaaagca cattataaaa atgaagaaat
    46501 tgatctcaaa ccaaaggaat tactggtact aaagtgtttg attcagcata aaaatcaagt
    46561 tttaagtaga gagcagatat tggaagaaat ttcaaaagat gtagctgatt taccttgtga
    46621 tagggtcgtt gatgtctata ttcgtactct tcgcaaaaaa ttagctttag attgtatcgt
    46681 gactgtgaaa aatgttgggt ataagattag cttatgataa aaaatcctaa attattaacc
    46741 aagtcttttt taagaagttt tgcaattcta ggtggtgttg gtctagtcat tcatatagct
    46801 atttatttga cctttccttt ttattatatt caactggagg gggaaaagtt taatgagagc
    46861 gcaagagtgt ttacggagta tttaaagact aagacatctg atgaaattcc aagcttactc
    46921 cagtcttatt caaagtcctt gaccatatct gctcacctta aaagagatat tgtagataag
    46981 cggctccctc ttgtgcatga cttggatatt aaagatggaa agctatcaaa ttatatcgtg
    47041 atgttagata tgtctgttag tacagcagat ggtaaacagg taaccgtgca atttgttcac
    47101 ggggtagatg tctacaaaga agcaaagaat attttgcttt tgtatctccc atatacattt
    47161 ttggttacaa ttgctttttc ctttgttttt tcttattttt atactaaacg cttgctcaat
    47221 cctctttttt acatttcaga agtgactagt aaaatgcaag atttggatga caatattcgt
    47281 tttgatgaaa gtaggaaaga tgaagttggt gaagttggtg aagttggaaa acagattaat
    47341 ggtatgtatg agcacttgtt gaaggttatt catgagttgg aaagtcgtaa tgagcaaatt
    47401 gtaaaattgc aaaatcaaaa ggtttccttt gtccgcggag catcacatga gttgaaaacc
    47461 cctttagcca gtcttagaat tatcctagag aatatgcagc ataatattgg agattacaaa
    47521 gatcatccaa aatatattgc aaagagtata aataagattg accagatgag ccacttatta
    47581 gaagaagtac tggagtcttc taaattccaa gagtggacag agtgtcgtga gaccttgact
    47641 gttaagccag ttttagtaga tattttatca cgttatcaag aattagctca ttcaataggt
    47701 gttacaattg aaaatcaatt gacagatgct accagggtcg tcatgagtct tagggcattg
    47761 gataaggttt tgacaaacct gattagtaat gcaattaaat attcagataa aaatgggcgc
    47821 gtaatcatat ccgagcaaga tggctatctc tctatcaaga atacatgtgc gcctctaagt
    47881 gaccaagaac tagaacattt atttgatata ttctatcatt ctcaaatcgt gacagataag
    47941 gatgaaagtt ccggtttggg tctttacatt gtgaataata ttttagaaag ctatcaaatg
    48001 gattatagtt ttctccctta tgaacacggt atggaattta agattagctt gtagacagat
    48061 tagtttttta ttaaagttca tatagggtta acataagtgt attattcttt atatagataa
    48121 aaatatagat aaaagaaagg atactaatat ggtattagcg attattttag taacattcct
    48181 tattcgattg atttttttaa agcgttcgat agagaatgag aaacgaatcc ttagcaatgg
    48241 cgggaaagaa tttggagttg agaatacaaa acgattaacg ttggctcata ttgtttttta
    48301 tctctcttgc ctcgttgaag caatggtgca taagacaatg tttgatggta tgagcatggt
    48361 tggtttagtc ttgcttattt tttctatgct gatgttgatg ttggtgattc acttgttggg
    48421 agatatttgg acagtgaagc ttatgcttgt caataatcac aaatatgtag atcatatctt
    48481 gtttaggaca gtaaaacatc ctaattactt tttaaatatt ttacctgagt tgattggctt
    48541 gaccttgttg agtcatgcct atatgacttt tgttttagtt tttccagttt atgcagttat
    48601 tttgtatcga cgaatagctg aagaggaaaa gctattacat gaagttataa tcccaaatgg
    48661 aagcataaag agataaatac aaaattcgat ttatatacag ttcatattga agtgatatag
    48721 taaggttaaa gaaaaaatat agaaggaaat aaacatgttt gcatcaaaaa gcgaaagaaa
    48781 agtacattat tcaattcgta aatttagtat tggagtagct agtgtagtag ttgctagtct
    48841 tgttatggga agtgtggttc atgcgacgga gaatgaggga attacccaag tagccacttc
    48901 ttataataag gcaaatgaaa gtcagacaga acataggaaa gctgctaaac aagtcgatga
    48961 agatataaaa aaaatgttga gtgagatcca agaatatata aaaaaaatgt tgagtgagat
    49021 ccaattagat aaaagaaaag atacccaaaa tcgcacctta aacagaaagt tgagcgcaat
    49081 tcaaacgaag tatttgtatg aattaagagt tttaaaagag aagtcgaaaa aagaagagtt
    49141 gacgtcaaaa acaaaaaaag agttagacgc agcttttgag aagtttaaaa aagaaccaga
    49201 acttactaaa aaattagcag aagctaaaca aaaagccaag gctcaaaaag aagaagattt
    49261 ccgtaactac ccaaccaata cttacaaaac gcttgaactt gaaattgctg agttcgatgt
    49321 gaaagttaaa gaagcggagc ttgaactagt aaaagaggaa gctaaacccc gaaacgagga
    49381 aaaaattaag caagcaaaag agaaagttga gagtaaaaaa gctgaggcta caaggttaga
    49441 agaaatcaag acagaacgta aaaaagcaga agaagaagct aaacgaaaag cagaagaatc
    49501 tgagaaaaaa gctgctgaag ccaaacaaaa agtggatact aaagagcaag gtaaaccaaa
    49561 gaggcgggca aaacgaggag tttctggaga gctagcaaca cctgataaaa aagaaaatga
    49621 tgcgaagtct tcagattcta gcgtaggtga agaaactctt ccaagcccat cccttaatat
    49681 ggcaaatgaa agtcagacag aacataggaa agatgtcgat gaatatataa aaaaaatgtt
    49741 gagtgagatc caattagata gaagaaaaca tacccaaaat gtcaacttaa acataaagtt
    49801 gagcgcaatt aaaacgaagt atttgtatga attaagtgtt ttaaaagaga actcgaaaaa
    49861 agaagagttg acgtcaaaaa ccaaagcaga gttaaccgca gcttttgagc agtttaaaaa
    49921 agatacattg aaaccagaaa aaaaggtagc agaagctgag aagaaggttg aagaagctaa
    49981 gaaaaaagcc aaggatcaaa aagaagaaga tcgccgtaac tacccaacca atacttacaa
    50041 aacgcttgaa cttgaaattg ctgagtccga tgtgaaagtt aaagaagcgg agcttgaact
    50101 agtaaaagag gaagctaacg aatctcgaaa cgaggaaaaa attaagcaag caaaagagaa
    50161 agttgagagt aaaaaagctg aggctacaag gttagaaaaa atcaagacag atcgtaaaaa
    50221 agcagaagaa gaagctaaac gaaaagcaga agaatctgag aaaaaagctg ctgaagccaa
    50281 acaaaaagtg gatgctgaag aatatgctct tgaagctaaa atcgctgagt tggaatatga
    50341 agttcagaga ctagaaaaag agctcaaaga gattgatgag tctgactcag aagattatct
    50401 taaagaaggc ctccgtgctc ctcttcaatc taaattggat accaaaaaag ctaaactatc
    50461 aaaacttgaa gagttgagtg ataagattga tgagttagac gctgaaattg caaaacttga
    50521 agttcaactt aaagatgctg aaggaaacaa taatgtagaa gcctacttta aagaaggttt
    50581 agagaaaact actgctgaga aaaaagctga attagaaaaa gctgaagctg accttaagaa
    50641 agcagttgat gagccagaaa ctccagctcc ggctcctcaa ccagctccag ctccagaaaa
    50701 accagctgaa aaaccagctc cagctccaga aaaaccagtt gaaaaaccag ctccagctcc
    50761 agaaaaacca gttgaaaaac cagctccagc tccagctcca gaaaaaccag ctccagctcc
    50821 agaaaaacca gctccaactc cagaaactcc aaaaacaggc tggaaacaag aaaacggtat
    50881 gtggtacttc tacaatactg atggttcaat ggcaacaggc tggctccaaa acaatggctc
    50941 atggtactac ctcaacagca atggcgctat ggcgacagga tggctccaaa acaatggctc
    51001 atggtactac ctcaacagca atggcgctat ggcgacagga tgg
//
LOCUS       DAVLUM010000003        46809 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLUM010000003 DAVLUM010000000
VERSION     DAVLUM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.003"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            79..6513
                     /locus_tag="VYN42_000134"
     CDS             79..6513
                     /locus_tag="VYN42_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1461285.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAMETSQDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKE
                     ENSNKSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYT
                     YDRIFNGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSI
                     NAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDK
                     IPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNA
                     QIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRA
                     LRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQ
                     TVEFDKVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLD
                     LRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEG
                     TKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNV
                     GDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVI
                     NGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIAL
                     QNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYG
                     SISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDG
                     KQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFES
                     VEEMEALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDG
                     KPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTS
                     GSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVV
                     SREHFIRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPAT
                     KIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLI
                     TKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTY
                     AGEGQGRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEK
                     GMISYYLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIE
                     GKSLFNIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIA
                     YDDGTDLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIE
                     IKATKYDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKE
                     TKSEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSNLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYINGKEYTSFNDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7139..7615
                     /locus_tag="VYN42_000135"
     CDS             7139..7615
                     /locus_tag="VYN42_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1461286.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7653..7958
                     /locus_tag="VYN42_000136"
     CDS             7653..7958
                     /locus_tag="VYN42_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1461287.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8006..9481
                     /locus_tag="VYN42_000137"
     CDS             8006..9481
                     /locus_tag="VYN42_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1461288.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9504..9581
                     /locus_tag="VYN42_000138"
                     /pseudo
     CDS             9504..9581
                     /locus_tag="VYN42_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            9831..16532
                     /locus_tag="VYN42_000139"
     CDS             9831..16532
                     /locus_tag="VYN42_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1461289.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKVKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKAVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPASEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16780..17636)
                     /locus_tag="VYN42_000140"
                     /pseudo
     CDS             complement(16780..17636)
                     /locus_tag="VYN42_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17846..18205)
                     /locus_tag="VYN42_000141"
     CDS             complement(17846..18205)
                     /locus_tag="VYN42_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1461290.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            18228..18806
                     /locus_tag="VYN42_000142"
     CDS             18228..18806
                     /locus_tag="VYN42_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846832.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEV1461291.1"
                     /translation="METRNRGIYRKVRLLRLWVIFVIMKVIKSYNTLNDYYRKLFGEK
                     TFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKW
                     PDVQKYLVYFQNFTNTHEKVEVIRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAE
                     LSECMHVTVELGLQTTYEATSDLINRAHSYEL"
     gene            18825..19253
                     /locus_tag="VYN42_000143"
     CDS             18825..19253
                     /locus_tag="VYN42_000143"
                     /inference="COORDINATES: protein motif:HMM:NF027524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461292.1"
                     /translation="MRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLKKWEVLNSIEMEMRRRGSVQGCKVVKQEFENEKTT"
     gene            19237..19794
                     /locus_tag="VYN42_000144"
     CDS             19237..19794
                     /locus_tag="VYN42_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1461293.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19787..20041
                     /locus_tag="VYN42_000145"
     CDS             19787..20041
                     /locus_tag="VYN42_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461294.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            20053..22107
                     /locus_tag="VYN42_000146"
     CDS             20053..22107
                     /locus_tag="VYN42_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1461295.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22286..23146
                     /locus_tag="VYN42_000147"
     CDS             22286..23146
                     /locus_tag="VYN42_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1461296.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            23357..24067
                     /gene="ccdA2"
                     /locus_tag="VYN42_000148"
     CDS             23357..24067
                     /gene="ccdA2"
                     /locus_tag="VYN42_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1461297.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQTS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            24087..24653
                     /locus_tag="VYN42_000149"
     CDS             24087..24653
                     /locus_tag="VYN42_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1461298.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24664..25776
                     /gene="msrB"
                     /locus_tag="VYN42_000150"
     CDS             24664..25776
                     /gene="msrB"
                     /locus_tag="VYN42_000150"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1461299.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            26044..26781
                     /locus_tag="VYN42_000151"
     CDS             26044..26781
                     /locus_tag="VYN42_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1461300.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            26778..28469
                     /locus_tag="VYN42_000152"
     CDS             26778..28469
                     /locus_tag="VYN42_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1461301.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMIAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            28585..29148
                     /locus_tag="VYN42_000153"
     CDS             28585..29148
                     /locus_tag="VYN42_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1461302.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKS"
     gene            29170..34638
                     /locus_tag="VYN42_000154"
     CDS             29170..34638
                     /locus_tag="VYN42_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1461303.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAQPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKSAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNSKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEVTTVETREEVIPFETKE
                     QEDDTLKRGTRQVVQKGVEGKKQITETYKTIRGEKTNEAPIVKETVIEQPQDEIIKKG
                     TKGLEKPTLQWANTEKDVLKKSATASYTLTKPAGVEIKSIKLALKDKDGQLVKEVTVA
                     ENNLNATLDKLKYYQGYTLSTTMVYDRGEGEETEKLEDKQIQLDLKKVEIKNIKETSL
                     MNVDAEGNETDKSLLSEKPTDVSQLYLRVTTHDNKVTRLAVSSVEEVVVDGKTLYKVV
                     AKAPDLVQRRADDTLSEEYVHYFEKQLPKVNNVYYNFNELVKDMQANPTGEFKLGADL
                     NAANVKPNGKSYVTKPFKGKLLSNDGGRFTIHNIERPLFANIEGGKIHDINLANVNIN
                     MPWADKVAPIANVIKNNATIENVKVTGNVLGKDWVSGFIDKIDGSGKLINVAFIGNVT
                     SVGTGGNFLTGIVGENWKGYVERAYVDAHIKGKRAKAAGIAYWSQNQGNNFTIGSEGA
                     IKKSVVKGTIDVEKPIEVGGAVGSFTYHGSIEDTVSMMKVKNGEIFYGSKDIDDDPYY
                     TGNHVNRNYVVIGVSEGTSTYRYSNQHNRIKPITQSEADVKIAETAITADKFTITDPI
                     VNKLNALTTRDNEYRTTQDYKATREQAYRNIEKLQPFYNKEWIVNQGNKLVEGSNLLT
                     KEVLSVTGIKSGQFVTDLSDIDKIMIHYSDGAKEELNVTRQESNVQQVREYSITDLDI
                     LYTPNMVEKDRAQLMTDVKSKLSSVELESDGVRQLLVKRDTKKDANANSVGRQNGYIR
                     DLFLEESFSEVKANLDKLVKQILENEDHQLNDNELAERALLKKVEDNKAKIMMGLAYL
                     NQYYAFKYDELSIKDIMMFKPDFYGKTASVIDRLINIGSAENNLKGDRTQDAYRGIIS
                     GATGKGSLHDFLTYNMKLFTNETDINVWFKKAIEKNAYVVEQPSTNPAFANKKYRLYE
                     GINNGQHGRMILPLLNLKNAHLFMISTYNTISFSSFEKYGKDTDEKREKFKSEINKRA
                     KEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHNSPNGWASRHGHIDGKPDYAP
                     IREFFGRINKYHGYKYGYGAYAYIFAAPQPMDAVYFVMTDLISDFGTSAFTHETTHVN
                     DRMAYYGGHWHREGTDLEAFAQGMLQTPSVSNPNGEYGALGLNMAYERQNDGNQWYNT
                     NPNDLTTRAEIDNYMKGFNDTLMLLDYLEGEAVLNKANQDLNNAWFKKVDKQLRGAST
                     KNQYDKVRDLTADEKNITLNSVDDLVDNNFMTKHGPGNNVYDPTGFGTAYVTVPITAG
                     IYGGNTSEGAPGSMSFKHNTFRMWGYYGYEKGFLNYASNMLKNESRQAGHNTLGDDFI
                     IKKVSDNKFSTLEDWKKAYFKEVVDKAKAGFNPVTIDSTTYSSYDDLKNAFAAAVEKD
                     KATLKNGSVKSDNTVALKEKIYKKLLQQTDSFKTSIFR"
     gene            34699..36420
                     /gene="pabB"
                     /locus_tag="VYN42_000155"
     CDS             34699..36420
                     /gene="pabB"
                     /locus_tag="VYN42_000155"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1461304.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLTVHKVPLLGEYLLYFTVHDRVETSPVPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRSHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            36421..37038
                     /locus_tag="VYN42_000156"
     CDS             36421..37038
                     /locus_tag="VYN42_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1461305.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFFELLK"
     gene            37088..37846
                     /locus_tag="VYN42_000157"
                     /pseudo
     CDS             37088..37846
                     /locus_tag="VYN42_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            37973..38932
                     /locus_tag="VYN42_000158"
     CDS             37973..38932
                     /locus_tag="VYN42_000158"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1461306.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            39029..39868
                     /locus_tag="VYN42_000159"
     CDS             39029..39868
                     /locus_tag="VYN42_000159"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1461307.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTSFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(39916..40086)
                     /locus_tag="VYN42_000160"
     CDS             complement(39916..40086)
                     /locus_tag="VYN42_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1461308.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            40207..41091
                     /gene="miaA"
                     /locus_tag="VYN42_000161"
     CDS             40207..41091
                     /gene="miaA"
                     /locus_tag="VYN42_000161"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1461309.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            41084..42322
                     /gene="hflX"
                     /locus_tag="VYN42_000162"
     CDS             41084..42322
                     /gene="hflX"
                     /locus_tag="VYN42_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1461310.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     NYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            42315..42938
                     /locus_tag="VYN42_000163"
     CDS             42315..42938
                     /locus_tag="VYN42_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1461311.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            42953..43882
                     /locus_tag="VYN42_000164"
     CDS             42953..43882
                     /locus_tag="VYN42_000164"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1461312.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            43903..44658
                     /locus_tag="VYN42_000165"
     CDS             43903..44658
                     /locus_tag="VYN42_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1461313.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(44712..45620)
                     /locus_tag="VYN42_000166"
     CDS             complement(44712..45620)
                     /locus_tag="VYN42_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1461314.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            45684..45953
                     /locus_tag="VYN42_000167"
     CDS             45684..45953
                     /locus_tag="VYN42_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1461315.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            45953..46333
                     /locus_tag="VYN42_000168"
     CDS             45953..46333
                     /locus_tag="VYN42_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1461316.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            46422..46649
                     /locus_tag="VYN42_000169"
     CDS             46422..46649
                     /locus_tag="VYN42_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461317.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
BASE COUNT        15032 a         8360 c        10185 g        13232 t
ORIGIN      
        1 aaaacttttt ataacaaagg ctagcaaagt taaagtttat tatctattgg aagttatata
       61 aatatgtaag gaattaaaat gaaaaaaagt acagtattgt cattaaccac agctgcagtt
      121 attttagcag cctatgcccc taatgaggta gtcttagcag acacatctag ctctgaagat
      181 gctttaagca tctctgataa agaaaaagta gtagtagata aggaaacaga aaataaagag
      241 aaacataaag atattcataa tgctatggaa acttcacagg atactgaaga aaagaaaaca
      301 acaattattg aggaaaaaga agttgttagt aaaaatcctg tgatagacac taaaactagc
      361 aatgaagaag caaaaatcaa agaagaaaat tccaataaat cccaaggaga tcatacggac
      421 tcatttgtga ataaaaacac agaaaatccc aaaaaagaag ataaagttgt ctatattgct
      481 gaatttaaag ataaagaatc tggagaaaaa gcaatcaagg agctatccag tcttaagaat
      541 acaaaagttt tatatactta tgatagaatt tttaacggtg gtgctattga aacaactcaa
      601 gataatctga ataaaattaa acaaatagaa ggtattacat cggttgaaag ggcacaaaaa
      661 gtccaaccca tgatgaatca tgccagaaag gaaattggag ttgaggaagc tattgattac
      721 ctaaagtcta tcaatgctcc gtttgggaaa aattttgatg gtagaggtat ggtcatttca
      781 aatatcgata ctggaacaga ttataggcat aaggctatga gaatcgatga tgatgccaaa
      841 gcctcaatga gatttaaaaa agaagactta aaaggaactg ataaaaatta ttggttgagt
      901 gataaaatcc ctcatgcgtt caattattat aatggtggca aaatcactgt agaaaaatat
      961 gatgatggaa gggattattt tgacccacat gggatgcata ttgcagggat tcttgctgga
     1021 aatgatactg aacaagatat caaaaacttt aacggcatag atggaattgc gcctaatgca
     1081 caaattttct cttataaaat gtattctgac gcaggatctg ggtttgcggg tgatgaaaca
     1141 atgtttcatg ctattgaaga ttctatcaaa cacaacgttg atgttgtttc ggtatcatct
     1201 ggttttacag gaacaggtct tgtaggtgag aaatattggc aagctattag ggcattaaga
     1261 aaagcaggca ttccaatggt tgtcgctacg ggtaactatg cgacttctgc ttcaagttct
     1321 tcatgggatt tagtagcaaa taatcatctg aaaatgaccg acactggaaa tgtaacacga
     1381 actgcagcac atgaagatgc gatagcggtc gcttctgcta aaaatcaaac agttgagttt
     1441 gataaggtta acattggagg acaaagtttt aaatacagaa atataggggc ctttttcgat
     1501 aagaataaaa tcacaacaaa tgaagatgga acaaaagctc ctagtaaatt aaaatttgta
     1561 tatataggca aggggcaaga ccaagatttg ataggtttgg atcttagggg caaaattgca
     1621 gtaatggata gaatttatac aaaggattta aaaaatgctt ttaaaaaagc tatggataag
     1681 ggtgcacgcg ccattatggt tgtaaatact gtaaattact acaatagaga taattggaca
     1741 gagcttccag ctatgggata tgaagcggat gaaggtacta aaagtcaagt gttttcaatt
     1801 tcaggagatg atggtgtaaa gctatggaac atgattaatc ctgataaaaa aactgaagtc
     1861 aaaagaaata ataaagaaga ttttaaagat aaattggagc aatactatcc aattgatatg
     1921 gaaagtttta attccaacaa accgaatgta ggtgacgaaa aagagattga ctttaagttt
     1981 gcacctgaca cagacaaaga actctataaa gaagatatca tcgttccagc aggatccaca
     2041 tcttgggggc caagaataga tttactttta aaacccgatg tttcagcacc tggtaaaaat
     2101 attaaatcca cgcttaatgt tattaatggc aaatcaactt atggctatat gtccggaact
     2161 agtatggcga ctccaatcgt agcagcttct actgttttga ttcgaccaaa attgaaggaa
     2221 atgcttgaaa aacccgtatt aaaaaatctt aaaggtgatg ataaaataga ccttacaagt
     2281 cttacaaaaa tagccctaca aaatactgca agacctatga tggatgcaac ttcttggaaa
     2341 gaaaaaagtc aatactttgc atcacctaga cagcaggggg cggggctaat taatgtggcc
     2401 aacgctttga gaaatgaagt tgtagcgact ttcaaaaaca cggattctaa aggtttggta
     2461 aattcatatg gttccatttc tcttaaagaa ataaaaggtg ataaaaaata ctttacaatt
     2521 aagcttcaca atacatccaa caggccttta acctttaaag tttcagcatc agcggtgact
     2581 acagattctc taactgacag actaaaactg gatgaaacat ataaagatga aaaatctcca
     2641 gatggtaagc aaattgttcc agaaattcat ccagaaaaag tcaaaggggc aaatattaca
     2701 tttgagcatg acactttcac tataggggca aattctagct ttgatttaaa tgcggttata
     2761 aatgttgggg aggctaaaaa taaaaataaa tttgtagaat catttattca ttttgagtca
     2821 gtagaagaaa tggaagcatt aagctccaat ggcaagaaaa ccgacttcca accatcttta
     2881 tcaatgcccc taatgggatt tgctgggaat tggaaccacg aaccaatcct tgataaatgg
     2941 gcttgggaag aaggatcaaa atcaaaaaca atggaaggtt atgatgatga cggtaaacca
     3001 aaaattccag gaaccttaaa taaggggatt ggtggagaac atggtataga taaatttaat
     3061 ccagcaggag ttatccaaaa tagaaaagat aaaaatagaa catctctaga tcaagatcca
     3121 gacttatttg cctttaacaa ccaaggtgtt catgcagaat ccactagtgg ttctaagatt
     3181 gctaacattt atcctttaga ttcaaatgga aatcctcaag atgctcaact agaaagagga
     3241 ctaactccat ctccacttgt tctaagaagt gcagaagaag gactaatttc aattgtaaac
     3301 accaacaaag aaggagaaaa ccaaaaagac cttaaagttg tatcaagaga gcacttcata
     3361 agaggaattc taaattctaa gggaaatgac gctaagggta tcaaatcatc caaactaaaa
     3421 gtttggggtg acttgaaatg ggatggactc atctataacc caagaggtag agaagaaaat
     3481 gccccagaaa gtaaggataa ccaagatcca gctactaaga tacgaggaca atttgaaccg
     3541 attgcggaag gtcaatattt ctataaattt aaatatagat taactaaaga ttacccatgg
     3601 caggtttcct atattcctgt aaaaattgat aacacagccc ctaagattgt ttcggttgat
     3661 ttttcaaatc ctgaaaaaat taagctaatc acaaaggata cttatcacaa ggtaaaagat
     3721 caatacaaga atgaaacttt atttgctaga gatcaaaaag aacatcctga aaaatttgat
     3781 gagattgcaa atgaggtgtg gtatgcagga gctgctcttg ttaatgaaga tggagaggtt
     3841 gagaaaaatc ttgaagtaac ttatgcaggt gagggtcaag gaagaaatag gaagcttgat
     3901 aaagatggga atactatcta tgaaattagc ggagcaggag atctaagagg aaaaatcatc
     3961 gaagtaatcg ccctagatgg agcaagcaac tttaccaaaa tccataggat taaatttgct
     4021 aatcaagctg atgaaaaagg gatgatttcc tattatctag tagatcctga tcaggattca
     4081 tctaaatacc aaaagcttgg cgaaattcct gaatctaaat ttaagaattt aaaaaatgtt
     4141 aaagatgata gcctaaacaa agagacagct gaggtggaaa ataacctttt agtagataat
     4201 cagtctatcg aaggaaaatc tctctttaat attcataaaa ctatttcaac aattagagac
     4261 tttgaaaata aagacctaaa gaaactcatt aaaaagaaat ataagcaaga agacgacttt
     4321 gtaaatggtg gaacaagaac agtagagcgt gattataaat acgatgataa aggaaatata
     4381 atagcctacg atgatgggac tgatctagaa tatgaaactg agaaacttga cgaaatcaaa
     4441 tcaaaaattt atggtgttct aagtccgtct aaagatggac actttgaaat tcttggaaag
     4501 ataagtaatg tttctaaaaa tgccaaggta tattatggga ataactataa atctatagaa
     4561 atcaaagcga ccaagtatga tttccactca aaaacgatga catttgatct atacgctaat
     4621 attaatgata ttgtggatgg attagctttt gcaggagata tgagattatt tgttaaagat
     4681 aatgatcaga aaaaagctga aattaaaatt agaatgcctg aaaaaattaa ggaaactaaa
     4741 tcagaatatc cctatgtatc aagttatggg aatgtcatag aattagggga aggagatctt
     4801 tcaaaaaaca aaccagacaa tttaactaaa atggaatctg gtaaaatcta ttctgattca
     4861 gaaaaacaac aatatctgtt aaaggataac atcattctaa gaaaaggcta tgcactaaaa
     4921 gtgactacct ataatcctgg aaaaacggat atgttagaag gaaatggagt ctatagcaag
     4981 gaagatatag caaaaataca aaaggccaat cctaatctaa gagtcctttc agaaacaaca
     5041 atttatgctg atagtagaaa tgttgaagat ggaagaagta cccaagctgt attaatgtcg
     5101 gctttggacg gctttaacat tataaggtat caagtgttta catttaaaat gaacgataaa
     5161 ggggaagcta tcgataaaga cggaaatctt gtgacagatt cttctaaact tgtattattt
     5221 ggtaaggatg ataaagaata cactggagag gataagtcca atgtagaagc tataaaagaa
     5281 gatggctcca tgttatttat tgataccaaa ccagtaaacc tttcaatgga taagaactac
     5341 tttaatccat ctaaatctaa taaaatttat gtacgaaatc cagaatttta tttaagaggt
     5401 aagatttctg ataagggtgg ttttaactgg gaattgagag ttaatgaatc ggttgtagat
     5461 aattatttaa tctacggaga tttacacatt gataacacta gagattttaa tattaagctg
     5521 aatgttaaag acggtgacat catggactgg ggaatgaaag actataaagc aaacggattt
     5581 ccagataagg taacagatat ggatggaaat gtttatcttc aaactggcta tagcaatttg
     5641 aatgctaaag cagttggagt ccactatcag tttttatatg ataatgttaa acccgaagta
     5701 aacattgatc ctaagggaaa tactagtatc gaatatgctg atggaaaatc tgtagtcttt
     5761 aacatcaatg ataaaagaaa taatggattc gatggtgaga ttcaagaaca acatatttat
     5821 ataaatggaa aagaatatac atcatttaat gatattaaac aaataataga caagacacta
     5881 aacattaaga ttgttgtaaa agattttgca agaaatacaa ccgtaaaaga attcatttta
     5941 aataaagata cgggagaggt aagtgaatta aaacctcata gggtaactgt gaccattcaa
     6001 aatggaaaag aaatgagttc aacgatagtg tcggaagaag attttatttt acctgtttat
     6061 aagggtgaat tagaaaaagg ataccaattt gatggttggg aaatttctgg tttcgaaggt
     6121 aaaaaagacg ctggctatgt tattaatcta tcaaaagata cctttataaa acctgtattc
     6181 aagaaaatag aggagaaaaa ggaggaagaa aataaaccta cttttgatgt atcgaaaaag
     6241 aaagataacc cacaagtaaa ccatagtcaa ttaaatgaaa gtcacagaaa agaggattta
     6301 caaagagaag atcattcaca aaaatctgat tcaactaagg atgttacagc tacagttctt
     6361 gataaaaaca atatcagtag taaatcaact actaacaatc ctaataagtt gccaaaaact
     6421 ggaacagcaa gcggagccca gacactatta gctgccggaa taatgtttat agtaggaatt
     6481 tttcttggat tgaagaaaaa aaatcaagat taggacaaaa gctatagaaa aaaatggttt
     6541 atgtactgag attagatagt gaggtgatga catagttttg tgaaaacagc catttataat
     6601 tcaattattt agtttacttc actattgata ctatttggag ttattaatgg acttagttta
     6661 gataactaat gaattgattg aaagggttag tattgacaat attggtcata ttgattagaa
     6721 aatagagtct atcaaaattt aaaggctaat agaggtgatg agacaatttc aaggaattaa
     6781 gtagcgtttg gttgcttaat tcctttttat ttggaaggaa gtttttcgta accgcccaat
     6841 aacgaagtct attggacggt tacgatatga tcactgactt cgtcagttct atctacaacc
     6901 taaaaacagt gttttgaaca acctgcggct agctttctag tttgctcttt gattttcatt
     6961 gaatattaga acagcaaaaa tgcttggagt atttgtttgt gtgtttgttt ttatataaca
     7021 aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa agaacagaaa gtaattgaca
     7081 acggtttcat atagtgttat acttatggca taaagttaat ggaaagaagg gaaaacttat
     7141 ggtattagat tatttctttg acaaaaacct tgtgttttgc ttagaagcgg ataatcaaga
     7201 acaactcttt gatcaggttg caactttatt ggaagaacga gaaattgtca ctccaactta
     7261 tcgtgaagcc ttgatcacgc gtgaaaagtc atttccaact ggtttagata tggaatttct
     7321 aggaaaggac ttgccaaatg tagcgattcc tcatacagat attgttcata atctagctga
     7381 gaaagtggtg gttgttcgat tagaaaaacc agtaactttt cacaatatga tagctcctga
     7441 taaggaagta gaagtatcct tgctcttctt tatcatcaat aactcaagtt caagtcaaac
     7501 aaatattctg gctcagttga tggacttttt cacaggaaat ggacatcttg aagacctatc
     7561 aaaaatttcc gaaccagaaa aactttatgc ttacattgct gaagcaaccg cttaatcttg
     7621 tctattaaaa aataaaatcg gaggaaatcc aaatgattaa aattcttgct gcctgcggtg
     7681 caggtgttaa ctcaagtcac caaattaaaa gtgctctaga agaagaactt tcaaaccgtg
     7741 gttatgatgt tcactgtgat gcagtcatgg tgaaagatgt aaacgaagac cttatgaaag
     7801 gttacgatat ctttacacca atcgctgcaa cagaccttgg ttttgaacca ggtatcccag
     7861 ttatcgaagc tggaccaatc ttattccgta tcccagcaat gagcgctcca gtatttgaca
     7921 atattgaagc agctattaaa gaacacggat taagctaatt ctaatttgtt aacattcata
     7981 taacataaaa aagggaggaa ctgttatgga tgcaatcttt gacctaatcg gaaaggtttt
     8041 caatcccatc ttagaaatgg gtggacctgt catcatgtta atcattttga cagtattggc
     8101 tttacttttt ggagtgaaat tctccaaagc gcttgaaggt ggtatcaaac ttgccatcgc
     8161 tcttacaggt atcggtgcta tcatcggtat gctaaatggt gctttctcag catcacttgc
     8221 aaaattcgtt gaaaacactg gtatacaatt gagtattacc gacgttggtt gggcaccact
     8281 cgcaacaatc acttggggtt ctgcttggac actatacttc ttgctcatca tgttgattgt
     8341 caacgtagtg atgcttgcta tgaagaaaac cgatacactt gatgtcgata tctttgatat
     8401 ctggcacttg tctatcacag gtctcttgat taaatggtat gctgataaca atggtgtgag
     8461 tcaaggggtt tcactcttta ttgctacagc agctatcgtc cttgtcggtg tgttgaaaat
     8521 tatcaactct gacttgatga aacctacatt tgatgacctt cttaacgccc caagttcatc
     8581 accaatgaca tcaactcaca tgaactacat gatgaaccca gttatcatgg ttttggataa
     8641 gatttttgaa aaattcttcc caggccttga taaatatgac tttgatgctg ctaaattgaa
     8701 caagaaaatc ggtttctggg gatctaaatt cttcatcggt ttcatccttg gtatcgttat
     8761 tggtattatg ggaactccac atccaattgc aggtgttgca gatgcagata aatggcgtct
     8821 tgttatcaaa ggatggttgt ctcttggttt gactgccggt gtatctttgg aactcttctc
     8881 acttatcggt tcatggttca tcgcagccgt agaaccacta tcacaaggta ttacaaacgt
     8941 tgctactaaa cgtcttcaag gacgtaaatt caatatcggt cttgactggc cattcatcgc
     9001 tggtcgtgct gaaatctggg cttgtgccaa cgtacttgca ccaatcatgt tgattgaagc
     9061 agtgcttctt tcaaaagttg gaaatggtat cttgccactt gcaggtatca tcgctatggg
     9121 tgttactcca gcactcttgg ttgtaactcg tggtaaattg ctccgtatga ttatcttcgg
     9181 aacactcttg ttgccactct tccttctttc aggtacactt attgcaccat ttgcaacaga
     9241 acttgctaaa ggtgtaggtg ccttcccaga aggtgtgagc caaactcaat tgattactca
     9301 ctctactctt gaaggaccaa tcgaaaaact tcttggttgg acaattggta acactacaac
     9361 tggtgatatc aaagcaatcc ttggtgcagt agccttcctt gtattctata tcggtatctt
     9421 tgcttggtac agaaaacaaa tgatcaaacg taacgaagag tacgcagcaa aagcaaaata
     9481 atgcgctcct ataaaatata aactcaatga aaatcaaaga gcaaactagg aagctagccg
     9541 caggttgctc aaaacacagt tttgaggttg tagataagac tgacgaagtc agctcaaaac
     9601 atggttttga ggttgtagat gaaactgacg aagtcagctc aaaacatggt tttgaggttg
     9661 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacactg acgaagtttg
     9721 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     9781 tgggctttag tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     9841 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     9901 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     9961 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
    10021 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
    10081 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
    10141 caaaagagga aaaagtgtct gctaaaccgg aagaaaaagc tccaaggata gaatcacaag
    10201 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaagtga
    10261 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
    10321 caaattctaa ggaagccatt aaacctgatg cagacgtatc tacgtggaaa aaattagatt
    10381 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
    10441 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
    10501 acctcaagaa aaatgttcgc cttacttttg atggcgtcta tatggattct caagtttatg
    10561 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tacgatatca
    10621 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
    10681 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
    10741 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
    10801 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgtcaatacg gacgacaaag
    10861 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
    10921 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
    10981 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
    11041 tgattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
    11101 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
    11161 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
    11221 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
    11281 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
    11341 aagaggcctt tgatacgtgg tatggtggca agaaacctta tgactatgga cgtttctttg
    11401 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
    11461 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
    11521 aaataggtga agctaatggt gatgcccact ctttagcaac tgttaaacgt ttggttaagg
    11581 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
    11641 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
    11701 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
    11761 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
    11821 aacatagcaa tggacctgag cgtaattatg aacagtcaga ttatggaaat gatcgtgtgg
    11881 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
    11941 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
    12001 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
    12061 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
    12121 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
    12181 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
    12241 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
    12301 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
    12361 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
    12421 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
    12481 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
    12541 ctaataatct ggttcgcttc caattgcatg gccaaggtca actggtcggt gtagataacg
    12601 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
    12661 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
    12721 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
    12781 aaggacaaga gaagactgtt ttggggacag aagtgccaaa agtacagacc attattggag
    12841 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
    12901 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
    12961 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
    13021 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
    13081 atgttttgac tgatggaagt gttgaagagt atgaagtgga caagtgggag attgccgaag
    13141 aagataaagt taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
    13201 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
    13261 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
    13321 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
    13381 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
    13441 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
    13501 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
    13561 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
    13621 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttgc
    13681 ataagccagg agcagtcact ctgaacgctg aatatgaggg agctaaaggc caagttgaac
    13741 tcactatcca agccaatact gagaagaaga ttgcgcaatc catccgtcct gtaaatgtag
    13801 tgacagattt gcatcaggaa ccaagtcttc cagcaacagt aacagttgag tatgacaaag
    13861 gtttccctaa aactcataaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
    13921 atcaaacatt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaaaag
    13981 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
    14041 caccacaatt accagaaagt gttcggacat atgattcaaa tggtcacgtt tcatcagcta
    14101 aggttgcatg ggatgcgatt cgtccagagc aatacgctaa ggaaggtgtc tttacagtta
    14161 atggtcgctt agaaggtacg caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
    14221 ctgagcaagg tgcaaacatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
    14281 cttcagattc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
    14341 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
    14401 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
    14461 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
    14521 gtaaggctgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
    14581 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
    14641 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctatt cgtattcgca
    14701 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
    14761 aagttgcggc agccaagcaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
    14821 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttccggcag
    14881 tcacagcaaa tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
    14941 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat tttaggagaa taccgtctgc
    15001 acttcactaa ggataagaac ttactttctc ataaaccagt tgctgcggtt aaacaagctc
    15061 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
    15121 gtaaagacgg ctacgaaaca aaaaacctga cagttgaatg ggaagaagtt ccagcggaaa
    15181 atctgataaa agcaggtcaa tttaccgttc gaggccatgt ccttggtagt gatcttgttg
    15241 ctgaggtcac tgtacgagtg acagacaaac taggcgaagc tctttcagat aaccctaact
    15301 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
    15361 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
    15421 ggtctccaac accatcttct aatccagaag tatcagcggg tgtgatcttc cgtgaaaatg
    15481 gtaagattgt agaacggact gttgctcaag ccaaacttca cttctttgca gatagtggta
    15541 cggatgcacc aactaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
    15601 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
    15661 gggaagctgt gccttatcgt gcggataaag acatcgcagc tggtgatgaa atcaacgtaa
    15721 catttaaagc tgtcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
    15781 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
    15841 cgcaatcgaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
    15901 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
    15961 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
    16021 cagaaagtgg aaaacaagtc aaggaatacc gtatccagtt gactaaggaa aaaccagctt
    16081 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
    16141 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
    16201 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
    16261 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
    16321 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
    16381 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
    16441 gtgcggcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
    16501 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
    16561 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
    16621 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
    16681 tctcttattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
    16741 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttcattt cactatgttt
    16801 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac tcttgcctct
    16861 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttctacatc
    16921 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
    16981 agctttcaag ttttgatagc gttcgttcat atacaatccc ttttgagggg ctgattcagg
    17041 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
    17101 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
    17161 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
    17221 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
    17281 ttcttgaagt ttggcggaga atttctctgt cgttttcttc cacacaaaac tatacttgtt
    17341 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
    17401 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
    17461 acaagcattt tagggtgata agacgggcga ccaaaggcat gatagaaggc gtagaagtga
    17521 cgttcctcca aggtattcac cactttttca atagtaaaga cgagatggtc ttgtggtaag
    17581 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
    17641 tagtctttct aaatggttta ttaagcaatt ctattttacc aagactatcg taaccatgca
    17701 aaaaagcaac ggcaaatccg ttgccttttt ggatataaga gactattgtc ccagactctt
    17761 ttctttgtat aaaattgtat agtgttattg tctatactat tttgtagaga aagcaaaaat
    17821 ccctagaaaa tgcttaggga ttcgactatt tcattaagaa caattcaaca atcatttcta
    17881 tatacatgat aagggttaat aagaatcctg cacgccagaa gaatttgatg aatttaggat
    17941 agtaaaagct gcgttttttt aaaaggaaga aaaagacgag aataatggct aggaacgaga
    18001 gggctagccc cagtctaggg aggaaattat gggtaaaggt tttagctgta atcaagtaat
    18061 actcaaatac caagactgga aaagccaaat ccgcaaagtt tcgtcctagt ttttttaatc
    18121 taaaaagttt ggttaggata atgcagacga ctaaggtcag tatcaataat aaaatagatg
    18181 ctaatttcat taaaatcata cccatattgt atcataaaaa aaggctaatg gaaacgagaa
    18241 acagaggaat ttataggaaa gtcaggcttt tgagattgtg ggtgattttt gttataatga
    18301 aagttataaa atcttataat accttgaatg attattatcg aaaactgttt ggagaaaaga
    18361 cttttaaagt ccctattgat gcgggatttg actgtcccaa tcgtgatgga actgtggctc
    18421 atggaggctg tactttttgt acggtttcag gttctggaga tgctattgta gccccagatg
    18481 cgcctatccg tgagcaattt tataaggaaa ttgactttat gcaccgtaag tggccggatg
    18541 ttcagaagta tctggtttat tttcaaaatt ttaccaacac ccatgaaaag gtggaagtta
    18601 ttcgagagcg ttatgaacag gctatcaatg agccaggtgt ggtaggaatc aatattggaa
    18661 cgcgcccaga ctgtttacca gacgaaacca tcgaatattt ggctgagtta tcggagtgca
    18721 tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga agcaacctct gacctgatta
    18781 accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa gcgtttgaga aagtatccaa
    18841 aaattgagat tgtttcccat ttgataaatg gtttgcctgg tgaaacccat gagatgatgg
    18901 ttgaaaatgt ccgccgttgt gtcacggata acgatattca agggattaaa ctgcatttgc
    18961 tccatcttat gacaaatact cgtatgcaac gagattacca tgagggacgt ttacaattga
    19021 tgagtcagga cgaatatgtc agggtcatct gtgaccaact ggaaattatt cccaaacata
    19081 tcgtcatcca tcgaattaca ggagatgcgc ctagggatat gctgattggt cctatgtgga
    19141 gcctcaaaaa atgggaagtc ctcaacagca ttgagatgga gatgcgacgt cgtggaagtg
    19201 ttcaaggatg caaggttgta aaacaggagt ttgaaaatga aaagaccact tgagatggca
    19261 catgattttt tggctgaggt cgtgacaaaa gaggatgtcg tagtggatgc gactatggga
    19321 aatggtcatg acacgctttt tttagccaag ctagccaagc aagtctatgc ctttgatatt
    19381 cagaagcaag ccttggaaaa gacccaagag cgtttgcatc aggctgactt gacaaatgcc
    19441 cagttaatct tgcaaggcca tgagacactg gatcagtttg tgataaaagc taaggcaggg
    19501 atttttaatt tgggctattt gccgtcagct gataagtctg tcatcacccg accgcagaca
    19561 acgattgagg cattagaaaa gctatgtggc ttacttgtca aaggtggacg aattgctatt
    19621 atgatttact atggtcatga aggaggcgac ctcgagagag atgctgtctt ggattttgta
    19681 atccagttga accaacaaga gtacacagct gccatttacc gaactttaaa ccaagtcaac
    19741 aacccgccgt ttttagtgat gattgaaaaa ttagagagat acagacatgg ataaacaata
    19801 cctacacgaa aagctggatg ccatgcgcca gaattttgtt gaatcaaccc accacgaacg
    19861 atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa atgcttaaaa tcaagaaaaa
    19921 attagttgct cttgaaatgg aacggtgcca gagaaaaatt gagcacaaag actgttccaa
    19981 gattgaccaa aaaatcaaag agcagaagga gatatttgaa tcctgttgta aaaaagatta
    20041 aggaggacgt gcgtggaatt actgatttac ctcatcctat ttttactggt tttgattgtc
    20101 tcaagtacaa ccaataagct cctgcccttt ttgcctctcc ctttggtgca aattcttttg
    20161 ggaattgtga ttggtctctt tttacccaat actgactttc accttaatac ggagttgttt
    20221 ttggcactgg ttatcggacc cttgcttttc cgagaggctg aagaagcaga tgttacggct
    20281 attttaaaac actggcgaat cattgtttat ctcatatttc cagtgatttt tatctcgacc
    20341 ctgagtttgg gtggcttggc ccatcttctt tggttcagcc ttcccttggc agcttgcttg
    20401 gctgttggtg cagcccttgg tcctacggac ttggtggcct ttgcctctct ttcggagcgt
    20461 tttagctttc ctaagcgcgt gtccaatatt cttaagggcg aaggactctt gaatgatgct
    20521 tctggtttgg tggcttttca ggtagctttg acagcttgga caactggagc tttttctctg
    20581 gggcaagcta gcagttcgct catcttttca atcctaggcg gttttttaat tggattttta
    20641 acagccatga ccaaccgctt cctccatacc ttcttgctaa gtgtgcgcgc aacggatatt
    20701 gccagtgaac ttttattaga attgagtttg cctctagtga ccttctttct ggcagaagaa
    20761 gttcatgttt caggtattat tgccgtcgta gttgctggaa ttttaaaggc aagtcgcttc
    20821 aagaaaatca cgctcctcga agcccaagtg gatacggtga ccgagacggt ctggcataca
    20881 gtgaccttta tgctcaacgg ttctgtcttt gtgattttag ggatggagtt ggaaatgata
    20941 gcagaaccta tcttgaccaa tccaatctat aatcctctac ttttattgct atctcttatc
    21001 gcccttacct ttgtcctttt tgtcattcgt tttattatga tctatggcta ttatgcctat
    21061 agaacccgac gcctcaagaa aaagctaaat aagtatatga aggacatgtt tctcttgacc
    21121 ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc tcttgatacc aagtaatcta
    21181 gaacaggagt atcctctttt gcttttcctt gttgcaggtg tgacgcttgt tagcttttta
    21241 acaggtctct tggtcttgcc tcatctttct gatgaagagg aagaaagcaa ggattatctt
    21301 atgcatatcg ccattttgaa tgaagtaacg ctagagttgg aaaaagagtt ggaagacacc
    21361 agaaataaac ttcccctcta tgcggctatt gacaattatc atggacgtat tgaaaatctc
    21421 attttaagcc aagaaaacca ggatgatcaa gaagactggg ctgctttgaa actcttgatt
    21481 cttagtattg aaagtgatgg tttggaacag gcctatgaag aggggaacat tagcaatcgt
    21541 gcttaccgag tttaccaacg ttatctgaaa aatatagaac aaggaatcaa tcgtaaactt
    21601 gcctcaagac tgacctatta ttttcttgtt tccttgagga ttttacgttt tctccttcat
    21661 gaagttttta ctctcggaaa gaccttccgt agctggaaga acaaggagca aagccgtctc
    21721 cgtgctcttg attatgacca aattgcagag ctctatcttg ccaatacaga gatgattatt
    21781 gaaagtttgg aaaacctgaa gggagtctac agacgctctt tgattagttt tatgcaggag
    21841 tctcgtcttc gagaaacagc tattatcagc agtggtgcct ttgtcgaacg ggttatcaat
    21901 cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct attatctgga gcgcaagttg
    21961 attttcgaat acgaagaaaa acgattgatt acgactaagt atgccaagaa attacgacaa
    22021 aatgtaaata acttagagaa ctattccttg aaggaagctg ccaataccct accgtatgat
    22081 atggtggaat tggtaagaag aaattagtta atactcttcg aaaatctctt caaaccacgt
    22141 cagcgtcgcc ttaccgtatg tatgtgactg acttcgtcag tcttatctac aacctcaaaa
    22201 cagtgttttg agcagcttgc ggctagcttt ctagtttgct ctttgatttt cattgagtat
    22261 aagattataa gtgaaggagt atgacatgaa aaagtggtgg aaagagctga tagacaaacc
    22321 tttattaaaa gcttttttgc attattatca agcatcagat agtgagttga ccagtgtcgc
    22381 agtagcctac tattggttga tttcgatttt ccccctgctt ttggtggtgg tcaatatcct
    22441 cccctatttt cagattcctg tgggagaatt tttgggcttt atgaaagacg tcctgccccc
    22501 aagcctctat gaaggtgtgg aaaaaatagc cagagaagtc ttgacgcaac cttcaacagg
    22561 tttattgagt ttttctgttt tatcggcgtt atggagtttt tcaaaatcta tgaatttctt
    22621 gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt cgtggactta tttcccatca
    22681 gatgctaagt ctcctagtca gttttggctt gcagctcctc tttgcgtttg ccttgttttt
    22741 gatcttattt ggtcagatga ttttggcttt acttgctcat tattggacaa aagatggcat
    22801 tatctatcag gctttacaag ggttggcagg tcctctgatt tacgccctcc tctttgctat
    22861 cttggtcatg ctttattatt ttcttcccaa tctatctaac aggaaaatta gctataccct
    22921 accaggcagt gcctttgttc tcttagtgat tttaggttta ctaactctgt tctctagtta
    22981 tctcaattac tatgtccatc atttggtgga tgtccgaatt ttaggttccg ttcttcttgt
    23041 tgttatgatg ttttggttta tcttgattgc taaaattgtt atcctaggcg cggttatcaa
    23101 tgccagtatg cagagtttga aagatccggt ctttaaaaaa gactaactat ttatctatta
    23161 taaaagcgca tagtatcaag actttataga accttgatac tatgcgcttt tgtgctttga
    23221 cagttttttg tatagttttt gtccaagatt tctaaatcat ctgattaaat tcctattttc
    23281 ccctatcatt gtccctgttt tttcgaaaat ggaaggagta taataaatct atcaataaaa
    23341 tgataggagg aactttatgg gtcatatttt cttttttcta agtgtctttt tggcagggat
    23401 tctatccttc ttttctcctt gtatcttacc tttgttaccg gtctatacag gggtgttact
    23461 agatgataag gatggtgctc agacttctag cggcaaattt tcaatctcag ttactagttt
    23521 attacgaact ctggccttta tagcaggaat ttcctttata tttattttgt tgggctatgg
    23581 agctggtttt ttaggcgatt tgctttatgc ttcttggttc caatatctta ctggggcaat
    23641 tattatcctt cttggtttgc accaaatgga gattctacac tttaaggggc tttataagga
    23701 aaagaggcta caactgcaag gacaggggca aaatggtaag ggctatagtc aggcattttt
    23761 attgggcttg acctttagtt ttgcttggac gccttgcgtg gggccggttc tggggtctgt
    23821 tttggccttg gcggcttcag gtggttcagg agcttggcag ggagctggtc tcatgttggt
    23881 gtatacgctg ggcttggcgc taccattctt gcttctagct ctgacctcta gttatgtttt
    23941 gaaacatttc cgaaaacttc atccctatct cggaatcctc aaaaaagtgg gtggttttct
    24001 cattattgtg atgggactct tggttctgtt tggaaatgct tcaattttaa gtcaattatt
    24061 tgaataaaat ggaaaggaat atcaatatga aaaaatggca aacatgtgtt cttggagcag
    24121 gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt gactagtgaa caccaaacga
    24181 aagatgaaat gaagacggag cagacagcta gtaaaacaag cgcagctaaa gggaaagagg
    24241 tggctgattt tgaattgatg ggagtagatg gcaagaccta ccgtttatct gattacaagg
    24301 gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc catctgtctg gctagtcttc
    24361 cagatacgga tgagattgct aaagaagctg gtgatgacta tgtggtcttg acagtagtgt
    24421 caccaggaca taagggagag caatctgaag cggactttaa gaattggtat aagggattgg
    24481 attataaaaa tctcccagtc ctagttgacc catcaggcaa acttttggaa acttatggtg
    24541 tccgttctta cccaacccaa gcctttatag acaaagaagg caagctggtc aaaacacatc
    24601 caggattcat ggaaaaagat gcaattttgc aaactttgaa ggaattagcc taggaggtgt
    24661 ctcatgaatg ataagttaaa aatcttcttg ttgctaggag tattttttct agccataacc
    24721 ggtttctatg ttctattgat acgaaatgca gggcagacag atgcctcgca aattgaaaag
    24781 gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag aaattagtaa agacgcagac
    24841 ttgcacgaaa tttatctagc tggaggttgt ttctggggag tggaggaata tttctcacgc
    24901 gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg gtagaggaga aacaaccaag
    24961 tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc atgtcaccta tgatgccaag
    25021 caaatttctc tcaaggaaat cctgcttcac tatttccgca ttatcaatcc aaccagcaaa
    25081 aataaacaag gaaatgatgt ggggacccag taccgtactg gtgtttatta cacagatgac
    25141 aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg ctaagaaata cgatcaacct
    25201 ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg ctgaggatta ccatcaagac
    25261 tatctcaaga aaaatccaaa tggctactgc catatcaatg ttaatcaggc ggcctatcct
    25321 gtcattgatg ccagcaaata tccaaaacca agtgatgagg aattgaaaaa gaccctgtca
    25381 cctgaggagt atgcagttac ccaggaaaat caaacagaac gagctttctc aaaccgttac
    25441 tgggataaat ttgaatccgg tatctatgtg gatatagcaa ctggagaacc tctcttttca
    25501 tcaaaggaca agtttgagtc tggttgtggc tggcctagtt ttacccaacc catcagtcca
    25561 gatgttgtca cctacaagga agataagtcc tacaatatga cgcgtatgga agtgcggagc
    25621 cgagtaggag attctcacct tggccatgtc tttacggatg gtccacagga caagggcggc
    25681 ttacgttact gtatcaatag cctctctatc cgctttattc ccaaagacca aatggaagaa
    25741 aaaggctacg cttatttact agattatgtt gattaatact tttcgaaaat ctcttcaaac
    25801 cacgtcagcg tcgccttacc gtatgtaggg ttactgactt cgtcagtttt atctacaacc
    25861 tcaaagctat actttgagct gacttcgtca gttttatcta caacctcaaa gcggtacttt
    25921 gagaaacctg tggctatctt cctagtttac tttttgattt ttattgagta taagaggtct
    25981 ttcctaagca gttagaggag aattttgcta tactgatact agtaagtggt aaaggagcag
    26041 atcatgacct acacaatctt aatcgtagaa gatgaatatc tggtaagaca aggtttgact
    26101 aaactggtca atgtagcagc ctacgatatg gaaatcatcg gtcaggctga aaatggaagg
    26161 caggcttggg aattgatcca aaagcaggtg ccagatatca ttttaaccga tatcaacatg
    26221 cctcatctaa atggcatcca gttggccagt ctggtacgag aaacctatcc tcaggttcat
    26281 ttggtctttt taacaggtta cgatgatttt gattatgcct tgtctgctgt caaactaggt
    26341 gtggacgact acctgctcaa acccttttct cgtcaggata ttgaggaaat gttggggaaa
    26401 atcaaacaaa aactagacaa ggaagagaaa gaagagcagt tacaagattt attgactaat
    26461 aggtttgaag gaaacatggc ccagaaaatc cagtctcatc tggctgatag ccaatttagt
    26521 ttaaagtctt tagccagtga cttaggtttt agtccgacct atctgagttc cttgattaag
    26581 aaagagttgg gcttgccttt tcaggattat ctggtgagag aacgtgttaa acaagccaag
    26641 ctcttgcttt taactacaga tctgaagatt tatgagatcg cagagaaggt tggttttgaa
    26701 gatatgaact attttaccca acgttttaag cagattgcag gtgtgacacc tcgtcagttt
    26761 aagaagggag aagaccgatg aagcgttctt ctcttttagt tagaatggtt atttccatct
    26821 ttctggtctt tctcattctc ctagctctgg ttggaacttt ctactatcaa tcaagttctt
    26881 cagccattga ggccaccatt gagggcaaca gccaaacgac catcagccag actagccact
    26941 ttattcagtc ttatatcaaa aaactagaaa ccacctcgac tggtttgacc cagcagacgg
    27001 atgttctggc ctatgctgag aatcccagtc aagacaaggt cgagggaatc cgagatttgt
    27061 ttttgaccat cttgaagtca gataaggact tgaaaactgt tgtgctggtg accaaatctg
    27121 gtcaggtcat ttctacagat gacagtgtgc agatgaaaac ttcctctgat atgatagctg
    27181 aggattggta ccaaaaggct attcatcagg gagctatgcc tgttttgact ccagctcgta
    27241 aatcagatag tcagtgggtc atttctgtca ctcaagaact tgttgatgca aagggagcca
    27301 atcttggtgt gcttcgtttg gatatttctt atgaaactct ggaagcctat ctcaatcaac
    27361 tccagttggg gcagcagggc tttgccttca ttatcaatga aaaccatgaa tttgtctacc
    27421 atcctcaaca cacagtttat agttcgtcta gcaaaatgga ggctatgaaa ccctacatcg
    27481 agacaggtca gggttatact cctggtcaca aatcctacgt cagtcaagag aagattgcag
    27541 gaactgattg gacggtactt ggcgtgtcat cattggaaaa gttagaccag gttcggagtc
    27601 agctcttgtg gaccttgctt ggggccagtg tcacatctct tcttgtctgt ctctgcttag
    27661 tgtggttcag tcttaaacgc tggattgctc ctttgaagga tttgagagaa accatgttgg
    27721 aaattgcttc tggtgctcaa aatcttcgtg ccaaggaagt tggtgcctat gaactgagag
    27781 aagtaactcg ccaatttaat gccatgttgg atcagattga tcagttgatg gtagctattc
    27841 gtagccagga agaaacgacc cgtcagtacc aacttcaagc cctttcgagc cagattaatc
    27901 cacatttcct ctataacact ttggacacca tcatctggat ggctgaattt catgatagtc
    27961 agcgagtggt gcaggtgacc aagtccttgg caacctattt ccgcttggcg ctcaatcaag
    28021 gtaaggactt gatttgtctc tctgacgaaa tcaatcatgt ccgccagtat ctctttatcc
    28081 agaaacaacg ctatggagat aaactggaat acgaaattaa tgaaaatgtt gcctttgata
    28141 atttagtctt acccaagctg gtcctacaac cccttgtaga aaatgctctt taccatggca
    28201 ttaaggaaaa ggaaggtcag ggccatatta aactttctgt ccagaaacag gattcgggat
    28261 tggtcatccg tattgaggat gatggcgttg gcttccaaga tgctggtgat agtagtcaaa
    28321 gtcaactcaa acgtggggga gttggtcttc aaaatgtcga tcaacggctc aaacttcatt
    28381 ttggagccaa ttaccagatg aagattgatt ctagacccca aaaaggaacg aaagttgaaa
    28441 tatatataaa tagaatagaa actagctaac tcccagtcaa ttctgggagt tttatgcgta
    28501 attgggcaaa ctttctaggt tgtctatctt gctaaaaaca agaaaaaacg gtatgataga
    28561 agagtgacaa cagaggtaac agagatgaac gagacacaga ttcaaagaga aacacgtcag
    28621 gtagtggaag atgttttaga aaagaccaat ttgaaacagg gggccctttt tgttttaggt
    28681 ctatcttcta gtgaggtgct aggtggtcag attgggaaag aatccagtca agagattggt
    28741 gagctgatag tggagactat cttgggtatt ctaggtagta gaggtatcca tttagcagtt
    28801 caaggttgtg agcatgtcaa tcgggctctc gttgttgaac gtcaggtggc agagcagttt
    28861 ggtctggaaa ttgtcagtgt ccatcctact cttcatgcag gaggttcggg gcagttggca
    28921 gcctttaagt ttatgcagga tccagttgag gttgaattta tcaaggctca tgctggattg
    28981 gatatcggag acactgcaat tggcatgcat gtcaagcatg ttcaggttcc gattcgccct
    29041 attttgagag agattggtca tgcccatgta acggcactga ctagtcgtcc aaaattaatc
    29101 ggaggtgcgc gtgcgcacta tccgcaagac gctattagaa agtcttgaga atgaataaag
    29161 gagataaaag tgtttaaaaa agaccgtttt tcaattcgta agattaaggg agttgtaggc
    29221 tctgtatttc ttggaagcct tttgatggct ccttctgtag tggacgcagc cacctatcac
    29281 tatgtaaata aagagattat ttcacaagaa gctaaagatt taattcagac aggaaagcct
    29341 gacaggaatg aagttgtata tggtttggtg tatcaaaaag atcagttgcc tcaaacaggg
    29401 acagaagcat ctgttttgac agcttttggt ttgctgactg ttgggagctt gcttttaatc
    29461 tacaagagaa agaaaattgc tagcgtcttt ctagttggag ctatgggatt ggtagttctt
    29521 cctagtgcag aggctgtaga cccagttgcg accctagcgc tggctagtcg agagggtgtt
    29581 gttgaaatgg atggctatcg ctatgttggt tatctatcag gtgacatcct caaaacgctt
    29641 ggcttggaca ctgttttaga agaaacctca gcacaacctg gagaggtgac tgtagtcgaa
    29701 gttgagactc ctcaatcaac aacaaatcag gagcaagcta ggacagaaaa ccaagtagta
    29761 gagacagagg aagctccaaa agaagaagca cctaaaacag aagaaagtcc aaaggaagaa
    29821 ccaaaatcgg agataaaacc tactgacgac acccttccta aagtagaaga ggggaaagaa
    29881 gattcagcag aaccagctcc agttgaagaa gtaggtggag aagttgagtc aaaaccagag
    29941 gaaaaagtag cagttaagcc agaaagtcaa ccatcagaca aatcagctga ggaatcaaaa
    30001 gttgaaccac cagtagaaca agcaaaagtc ccagaacaac ccgtgcaacc tacacaagct
    30061 gagcaaccaa gtacaccaaa agaatcatca caagaagaca attctaaaga agatagggga
    30121 gcggaagaga caccgaaaca agaagatgaa cagccagcag aagccccaga aatcaaggtt
    30181 gaagaaccag tagaatcaaa agaggagact gttaatcaac ctgttgaaca accaaaagtg
    30241 gaaacgcctg ctgtagaaaa acaaacggaa ccaacagagg aaccaaaagt tgaagtaaca
    30301 acagttgaaa caagagaaga agtcattcct tttgaaacaa aagaacaaga agatgacact
    30361 ttaaaacgcg gaacaagaca agtagttcaa aaaggtgtag aaggtaagaa acaaattact
    30421 gaaacttata aaacaattcg tggagaaaaa acaaatgaag ctccaatagt taaggaaaca
    30481 gtaattgaac aacctcaaga tgagattatc aaaaaaggta caaaagggtt agaaaaacca
    30541 acattacaat gggctaatac tgaaaaagat gtcttgaaga agagtgctac agctagttat
    30601 acattgacta aaccagctgg tgtagaaatt aaatcaatta aattagcgct aaaagataaa
    30661 gatggacaac ttgttaaaga agtaacggta gctgaaaata atttaaatgc tactttagat
    30721 aaattgaaat attatcaagg ttacacccta tctactacaa tggtttatga tcgtggagaa
    30781 ggtgaagaaa ctgagaaatt agaagataaa caaattcaat tagaccttaa aaaagttgaa
    30841 atcaaaaaca ttaaagaaac aagcttaatg aatgttgatg ctgagggtaa cgaaactgat
    30901 aagagcttat tatctgaaaa accgacagat gtttcccaat tgtatttacg tgtgacaact
    30961 catgacaaca aagtgacaag acttgcggta agttcagttg aagaagttgt tgttgatgga
    31021 aaaacattgt acaaagttgt agccaaagct ccagacttag ttcaacgtag agctgatgat
    31081 acactgagtg aagaatatgt tcattatttt gaaaaacaat taccaaaagt aaataatgta
    31141 tactacaact tcaatgaact tgtaaaagat atgcaagcta atccaacggg tgagtttaaa
    31201 cttggtgcag acttgaatgc agcaaatgta aaacctaacg ggaaatctta tgtaacgaaa
    31261 ccatttaaag ggaaattact aagtaatgac ggcggtagat ttacaatcca taatatagaa
    31321 cgtccattat tcgctaatat tgaaggtggt aaaatccacg atattaatct tgctaatgta
    31381 aatattaata tgccttgggc tgataaagtt gctcctattg caaatgtaat caaaaataat
    31441 gcaaccattg aaaatgtcaa agttactggt aatgtcctgg gtaaagactg ggtatctgga
    31501 tttatagaca aaattgacgg cagtggtaaa ttaattaatg ttgcatttat cggtaatgtt
    31561 acatctgttg gtactggagg caacttctta acaggtattg tgggagaaaa ctggaaagga
    31621 tacgttgaaa gagcatatgt tgatgctcat attaaaggta agcgagctaa agctgcgggt
    31681 atagcctact ggtcacaaaa ccaagggaat aactttacta ttggatctga gggggctatt
    31741 aaaaaatctg ttgttaaagg tacaatagac gttgaaaaac caattgaagt tggtggcgct
    31801 gttggaagtt ttacttatca tggttctatt gaagatactg tttctatgat gaaagttaag
    31861 aacggtgaaa ttttctatgg ttctaaagat attgatgatg atccatatta cacaggtaac
    31921 catgttaatc gaaactacgt tgttataggt gttagcgaag gtacttctac atatagatat
    31981 tctaatcagc ataatcgtat taaacctata acacaatcag aagctgatgt taaaattgca
    32041 gagacagcta tcacagcaga taaatttaca attaccgatc caattgtaaa taaacttaac
    32101 gctctcacaa cacgtgataa tgagtataga acaacacaag attacaaggc gactcgcgaa
    32161 caagcttatc gcaatattga aaaacttcaa ccgttctata acaaagaatg gattgtcaac
    32221 caaggtaaca aacttgtaga aggttcaaac ttgttgacaa aagaagtatt atctgttaca
    32281 ggtataaaga gcggtcaatt cgtaactgat ttgtcagata ttgataaaat tatgattcac
    32341 tattctgatg gagcaaagga agaattgaat gttactcgtc aagaatcaaa cgttcaacaa
    32401 gtgcgtgagt acagtattac agatttagat atactctata caccaaatat ggttgagaaa
    32461 gatcgcgctc agttgatgac tgatgtaaag tctaagctat ctagtgtaga attagagtct
    32521 gatggagtgc gtcaacttct cgttaagaga gatactaaga aagatgcgaa tgcaaatagt
    32581 gtaggtcgtc aaaatggata cattagagat ttattccttg aagaaagttt ctctgaagtt
    32641 aaagcaaatc ttgacaaatt ggtaaaacag atacttgaaa atgaagatca tcaactcaac
    32701 gataacgaat tagctgaacg tgctttactg aagaaagttg aagataataa agctaaaatc
    32761 atgatgggac tggcatactt aaatcaatat tatgctttta aatacgatga gttatcaatt
    32821 aaagatatta tgatgtttaa acctgatttt tatggtaaga cagcaagtgt tattgataga
    32881 ttgattaata ttggttctgc agaaaataat ctaaaaggag atagaacgca agatgcttat
    32941 cgtggtataa tttcaggggc aacaggtaaa ggtagtttac atgacttctt gacctacaat
    33001 atgaaattat tcacaaatga aacagacata aatgtttggt ttaagaaagc tattgaaaag
    33061 aatgcttatg tagttgaaca accatcaacg aaccctgcat ttgccaacaa aaaatatcgt
    33121 ctatacgaag gaattaataa tgggcaacat gggcgcatga ttttacctct tcttaacttg
    33181 aaaaatgcac atctatttat gatttcaaca tacaacacta tctcgtttag ttcgtttgaa
    33241 aaatatggca aagacacaga tgaaaaacgt gaaaagttca agagtgagat caataaacgt
    33301 gctaaagagc aggttaatta cttagatttt tggtcacgtc ttgctactga taatgtccgt
    33361 gataaacttc ttaagagtca aaatgtagtt ccaactcctg tatgggataa tcataatagc
    33421 ccgaacggat gggctagtag acatggtcat atagatggga aaccagatta tgctccaatt
    33481 cgtgagttct ttgggcgaat caataagtat catggttaca aatatggata tggcgcatat
    33541 gcatatattt ttgcagcacc tcaaccgatg gatgcagttt atttcgttat gacagattta
    33601 attagtgact ttggaacatc tgcatttaca catgaaacta ctcacgttaa tgatcgtatg
    33661 gcttactatg gtggtcattg gcatcgtgaa ggtacggatc ttgaagcatt tgctcagggg
    33721 atgttacaaa cgccatcggt atcaaatcca aacggagaat atggcgcatt aggtctaaat
    33781 atggcgtatg aacgtcaaaa tgatggaaat caatggtata acacaaatcc aaacgacctt
    33841 acaactcgtg cagaaattga taactacatg aaaggtttca acgacacatt aatgcttctt
    33901 gattaccttg aaggagaagc tgtcctcaat aaagcaaatc aagatttaaa caacgcttgg
    33961 ttcaaaaaag tggataagca acttcgtgga gctagtacga agaaccagta tgataaagtt
    34021 cgtgatttaa cggcagatga gaaaaatatc actctaaatt cagtagatga tttagttgat
    34081 aataatttta tgacgaaaca cggacctgga aacaatgtat atgatccaac tgggttcgga
    34141 acggcctacg tgactgtacc tattactgca ggtatttatg gaggtaacac aagtgaaggt
    34201 gctcctggtt ctatgtcatt caaacataac acattcagaa tgtgggggta ctacggatat
    34261 gaaaaaggat tcttaaacta tgcttctaac atgctgaaaa atgagtctag acaggctggt
    34321 cacaatactc taggtgatga tttcatcatt aagaaagttt ctgataataa attcagtaca
    34381 ttggaagatt ggaagaaagc atacttcaaa gaagttgtag ataaagctaa agcaggattt
    34441 aaccctgtta caatcgacag tactacatat agtagttacg atgacttgaa gaacgcattt
    34501 gctgcagcag ttgaaaaaga taaagctact cttaaaaatg gatcagttaa atctgacaat
    34561 actgttgcac ttaaagagaa aatatacaaa aaacttcttc aacaaacaga tagctttaaa
    34621 acttcaatct ttagataatc gaaatctctc atctgctttg cggatgaggg ttttcttatt
    34681 ttatgctata cttaaggtat gcatagaaaa acagtgattg attttaggac tttaggggag
    34741 agatatacct ttacccagcc tattaaagag ttgaaaacga gaaatgtaga agaagtggca
    34801 gatttgctgg cacaagtgga aagctaccaa gagcaaggtt attatgtggt ggggtatgtc
    34861 agctacgagg ctgcacctgc ttttgaggag aaattaacag ttcacaaggt tcctctactg
    34921 ggcgagtact tgctttactt tactgttcac gatagggtag agacctcccc tgttcctctg
    34981 acttatgagg atattgattt gccctcaaat tggcaggaag tgacgtctgc agcagactat
    35041 gaaaaggcca ttgcccagat acaccatcac ttgaggcagg gagacaccta tcaggtcaac
    35101 tacaccgtcc aactcaagca aaagttaagt gccaatcctt ttgccatcta caatcgtatg
    35161 gtggtagagc aggaggcggg ctacaatgcc tacgtggaac atgacgagat ggcagtgatt
    35221 tccatgagcc cagagctctt ttttgagcaa aatgatcgcg agttgacaac acgaccaatg
    35281 aaggggacga ctcagcgtgg ggtaactgac caagaagatc ttgaacaggc cagttggttg
    35341 gaacaggatc ccaaaaatcg ctctgaaaat atgatgattg tggacctctt gcgcaatgat
    35401 atgaaccgta tttctgaagt tgggagcgag cacgtggagc gtctgtgtca ggtagagcag
    35461 tattcaactg tttggcagat gacttcgacc atcaagagtc agttgcgaga ggatgtggac
    35521 cttgttgaaa tcttccgctc actctttcct tgtggttcca taacgggtgc accgaaaatt
    35581 gcgacaatgg agattatcaa ggacttggag cctcaaccgc gtggagtcta ctgtggaacg
    35641 attggtctct tgcttccaaa tggacgacgg atttttaatg tggccattcg taccattcaa
    35701 cttcacaaag gtcaagccat ttatggagtt ggcggaggga ttacttggga tagcacatgg
    35761 gaatctgaat accgagaggt tcatcaaaag gcagcagttc tttatcgtaa acaagctcgc
    35821 ttccaactga ttacgacagg ggaaatcagc cagaagaacc tgctgtttga agatcaacat
    35881 ctggaaagac tgagaaaagc tagtcgttat tttgcttttc cttttgatgc agaagacttg
    35941 ggacacaaga ttgaggaaga gtgtcaggat tgtgaagcta atcgagatta ccgcttgcga
    36001 atcagcctta gcaaatctgg agagatagaa gtcaatcgtc aagtattaac ccctctcagt
    36061 acaagctttt gtcaggccca agtctgtctt caggaagctg ctttgaatca atcctttacc
    36121 tactttaaaa ccactcaccg atcgcatttg agcctaggag aacaagagaa gatttaccac
    36181 aataagtcag gagaactgct tgaaacctct ataggaaatt tggttctgaa aatcgctgga
    36241 aaactctaca caccgcctat ccgacttgga atcttgccag gaatttaccg tcagcatttg
    36301 ctagaaacag gacaggtaga agagaaagtc ttgaccttgg cagatttaac ccaagcagaa
    36361 gctatttacg gctgtaatgc agtgagaggc ttgtatgaac taagccttga ggagaactag
    36421 atgaaattga tatttttgca tgggttaggg cagtcagcag agtcttggaa agaagttcgg
    36481 aatctactga cagattatcc ttctgaggct atcgagttat ttccttctgg agttagtaac
    36541 tatcaacaag ctaaagagcg agtttatcag cacctagctc aagagacaga accttttgtt
    36601 ttgattggat tgtccttagg tgctgccctg acactagaac tttccagtta cgatttacca
    36661 aatcttcgag ctttgattct gtcaggatgc ccgcttaaat tagcagggaa tatcctattt
    36721 tatcttcagt tgctgatttt taaactactt cccaaaagag tatttgaaaa acagggagca
    36781 gacaagactc ttatggtcgg agtttctgag gaattgaaga cacttgattt aacggatata
    36841 gcagggactt gctcctatcc aaccttacta atttgtggca gcaaagataa accgaatctt
    36901 agttctatga aagctctcca tagactgtta acagattcgc agtttcagat cattcctgat
    36961 ggccctcatg tcttgaataa ggcaaaacca aaggagtttg tagaaaagac cagaagtttc
    37021 tttgaattgc tgaaataagt ttgataaaat aatattgaaa tcgatatcat aattatggga
    37081 gaaagaaatg aataaacgtc tatttttaaa aatgagtctg gtgacgttgc caattttagc
    37141 cttgttttca caaccagttt tggcggaaga aaacatccat ttttcgagct gtaaggaagc
    37201 ttgggcgaat ggctattcgg atattcacga gggagaacct ggttattctg ccaagttaga
    37261 ccgtgatcat gatggtgtgg cttgcgaatt gaaaaatgct cctaagggtg cttttaaagc
    37321 aaaacagtca acggctattc aaatcaacac aagttcagca acaacaagtg gttgggttaa
    37381 gcaggacggc gcttggtact actttgatgg aaatggaaat ctagtgaaaa atgcatggca
    37441 gggaagctat tacctgaaat cagatggtaa aatggctaaa ggtgaatggg tttatgatgt
    37501 cacctatcaa gcttggtatt atttgacatc agatggttct tatgcttaca gtacatggca
    37561 aggaaattac tatctaaaat cggatggtaa aatggctgtc aatgaatagg ttgatggtgg
    37621 acgttattat gttggcgctg acggagtttg gaaggaaggt caagcaagta cagtttcttc
    37681 tagtaatgat agcaatagtg aatattctgc tgctttagga aaggcaaaaa gttataattc
    37741 gttattccac atgtcaaaaa aacgtatgta tagacaatta acttctgatt ttgataaatt
    37801 ttcaaatgat gcagctcaat atgccattga tcatttagat gattaacaga tactggtagg
    37861 cgaaaaaatt ccttataatt catttacgca aacctttgca taagtgaatg gattttgata
    37921 tactagtact gtaagcattt tcaattacta cacaatgaaa aaggagaata tgatgagtca
    37981 aaagattatt gggattgacc ttggtggaac ttctatcaaa tttgcaatct taacaacagc
    38041 aggagaaatc caaggaaaat ggtcaatcaa gaccaacatt ttggatgagg gaagtcatat
    38101 cgttgatgat atgattgagt ctattcaaca tcgtttggac ttgcttggat tggcagcagc
    38161 ggacttccaa ggcattggaa tgggatcacc aggtgtggtt gaccgtgaca aagggactgt
    38221 tatcggtgcc tacaacttga actggaaaac ccttcaacca atcaaacaaa agattgaaaa
    38281 agctttgggc attccatttt tcatcgataa tgatgccaac gtagcagctc ttggtgagcg
    38341 ctggatgggt gctggagata accaaccaga cgttgtcttt atgacactcg gtactggtgt
    38401 tggtggtggt attgtcgcag aaggcaaatt gcttcatggt gttgctggtg cagcaggtga
    38461 acttggtcat atcactgttg actttgacca accaatctca tgtacttgtg gtaaaaaagg
    38521 ctgccttgag acagttgctt cagcaacagg gattgtcaac ttgactcgtc gctatgccga
    38581 tgaatacgaa ggcgatgcag ccttgaaacg cttgattgat aacggagaag aagtaactgc
    38641 taagactgtc tttgatctcg caaaagaagg agacgacctt gctttgattg tttaccgtaa
    38701 cttctcacgt tacttgggaa tcgcttgtgc taacattggt tcaatcctaa acccatcaac
    38761 aatcgtcatc ggtggtggtg tgtcagccgc gggagaattc cttctacaag gtgttcaaaa
    38821 agtttacgat gaaaatagtt tcccacaagt acgcacatct actaaattag ctcttgcaac
    38881 tctaggaaat gacgctggag ttatcggagc agcatcactt gtattgcaat aagataatga
    38941 gagaggaaaa tgctaaccta gagttagtaa tgttcctctt ttatttttta tgctatacta
    39001 gttaggacaa tgaatgaggt gaaacgaaat gacaaaagca gatacgattt ttaaagagaa
    39061 tattgaacgc attctaaagg aaggtgtttt ctcagagcag gctcgtccta agtacaagga
    39121 tgggactgtt gctaattcca agtatgtaac tggtgccttt tccgagtacg acttatctaa
    39181 aggagaattt cctatcacaa ccttgcgtcc cattgcaatc aaatccgcca tcaaagaagt
    39241 tctctggatt taccaagacc agtcaaatag cttagaagtg cttaatgaca agtacaatgt
    39301 tcactactgg aatgactggg aagttggaga cacgggaacc attggtgagc gctatggtgc
    39361 cgttgttaag aaacacgaca ttatcaataa gcttctcaaa cagttggaaa ccaatccttg
    39421 gaaccgccgc aatattattt cgctctggga ttaccaagct ttcgaagaaa cagatgggct
    39481 gctcccgtgc gcctttcaga ccatgtttga tgttcggcgt gttgatgggg aaatctatct
    39541 ggatgcgacc ttgacccagc gctccaatga tatgctggtg gcccaccaca tcaacgctat
    39601 gcagtatgtg gctttgcaga tgatgattgc taaacatttt ggctggaagg ttgggaagtt
    39661 cttctacttc atcaacaacc tccatatcta tgataatcaa tttgaacaag ctcaggaatt
    39721 gctccgtcgg gagccgtcaa actgccaacc acgcttggtt ttaaatgttc ctgatgggac
    39781 tagtttcttt gatatcaaag cagaagattt tgagttggtg gattatgacc ctgttaagcc
    39841 acagttgaag tttgacctag ctatttaaaa gaatagaaaa aagaagttga gaataatccc
    39901 aacttctttt gtttcttaac gtgatacgcg gcgacgagct gcttttttac ggttttcttc
    39961 gatgaaagct gctttttgct cttctggttc gattactttc tttttaaatg cgtatactgc
    40021 acctgcaacg gcagcgacag ttcctgcgac acctgttaca agacctttag cgaatccttt
    40081 agccatgagt cttcctcctt tatattctca atcagccagc ctcctcaaga ggtcacattt
    40141 ttctgactga cctttttgtg ttataataat agtaacgaaa aaatgggaat ttttcaagga
    40201 aaaaagatga aaacaaaaat aattgtgatt gttggaccga ctgctgttgg aaagacggct
    40261 ctagctattg aagttgcaaa gcgctttaat ggcgaagtgg ttagtggaga tagccagcaa
    40321 gtctatcgag gacttgatat tgggacggcc aaggctagtc cagaagagca ggcagctgtt
    40381 cctcatcatt taatcgatgt tagagagata accgagtctt actcggcttt tgattttgtt
    40441 tcagaagcta agatgactat tgaggatatt cacagccgtg gcaagctagc cattatcgcc
    40501 ggtgggactg gactttatat ccagagcttg ctagaaggtt accacctagg tggggagact
    40561 cctcatgagg agattttagc ttatcgagct agtttggagc catattcaga tgaggaatta
    40621 gcccatttgg tggagcaagc aggccttgag attccccagt ttaatcgtcg tcgtgctatg
    40681 cgtgccttag aaattgccca ttttggtcag gatttggaaa atcaagagat tttgtatgaa
    40741 ccgctgatta tctgcttgga tgatgaacgt agtcaacttt atgagcgtat caaccaccga
    40801 gtggatttga tgtttgaggc tgggcttttg gatgaggcca agtggctgtt tgaccattcc
    40861 cctaatgtac aggctgctaa aggaattggc tataaggaac tctttcctta tttccgtgga
    40921 gagcagacct tggaggaagc tcgtgagagt cttaaacagg cgacccgtcg ttttgccaag
    40981 cgtcagctga cctggttccg taatcgcatg caggtcacct tttatcagat tggagaatct
    41041 ggtgtacaag accgcatttt aagccagata gaggagtttt tagatgattg aaacggagaa
    41101 aaaagaggag cgagtcctgc tgattggtgt ggaattgcag ggtatggaca gttttgacct
    41161 ctccatggaa gaattggcta gtttagcgaa aacggcaggg gcagtcgttg tagataacta
    41221 cagacaaaaa cgtgaaaaat atgattccaa gaccttcgtc ggctctggta agttggaaga
    41281 gattgcgctt atggtggatg cagaagaaat cactactgtc atcgtcaaca accgtctgac
    41341 accaaggcag aatgtcaatc tagaggaagt tctgggtgtc aaggtcattg accgtatgca
    41401 gttgattttg gatatctttg ccatgcgggc tcgaagccat gaagggaagc tccaagtcca
    41461 cctagcccaa ctcaaatacc tcttgcctcg cttggttggt caggggatta tgctcagccg
    41521 tcaggcaggg ggaattggtt cccgtggtcc tggtgaaagc caactggagc tgaaccgtcg
    41581 tagcgttcgc aatcaaatca cggatatcga gcgccagctc aaggtggttg agaaaaatcg
    41641 ggcgactgtc agagaaaaac gtttggagtc tagcaccttt aagattggtt tgattggtta
    41701 taccaatgct gggaaatcaa ctatcatgaa catcttgacc agtaagaccc agtatgaagc
    41761 agatgagctc tttgcgactc tggatgcgac aaccaagagt attcatctgg gaggcaatct
    41821 ccaagtaact ttgacagata ccgttggctt tatccaagat ttgccgacag agttggtgtc
    41881 cagtttcaag tcaaccttgg aagaaagcaa gcatgtggac cttctggttc atgttatcga
    41941 tgctagcaat ccttatcacg aggagcatga aaaaacggtt ctctccatca tgaaagacct
    42001 ggacatggaa gatattcctc acttgacgct ttataataaa gcggatttgg tggaggattt
    42061 cacgcctacc caaacgccat ataccctcat ttctgccaag tctgaggaca gtcgtgaaaa
    42121 cttgcaagca ttattgctag ataagattaa ggaaattttt gaagcattta ccctgcgagt
    42181 gcctttttca aagtcctaca agattcatga tttagagagt gttgcaattc tggaagaacg
    42241 tgattatcag gaagacagcg aagtgattac aggctacatt tccgaaaaaa ataaatggag
    42301 gttagaagaa ttttatgact gatattaaag ctttggctct aaagtatgga ggttatacaa
    42361 gtctggacaa ggtctatctg gatcagcttc tagctggtaa aacagagcag gagcagttaa
    42421 cacttattac acctccgcca agtgttgtta atgcctactt tgcagaactc tatcagaaaa
    42481 agagtcctca ggctgcgacg gattattttg cagaactcag tcaggaactg aatctttaca
    42541 atactgagcc aagtttcacc ctagaaaata agccttttat tcggcttaat ctgtctggta
    42601 aatcctttgg tttttgttat gagagtgacg gccttggtcg gattttctct gaaaatgagg
    42661 agaaaatctc ggatgacttg ctctttgaaa ttgcgcaaat tttcccccat caattagtct
    42721 ttgaagagtc tggtaagatt tacatgaagc ctgtcgagga cgaggaagtt gtcagcctag
    42781 aaagtctcac agctttgact gatttggaaa gattggctga tggtcgaaaa cgtctcaaag
    42841 gctacagcca agaggattta ttgcaagaag ctgctgcttt ttctggcaaa cgctatttcc
    42901 gatcggaaaa ccgcacagcc atgttatata ttgattaatt agaaagtatc gaatggatat
    42961 tcaattttta ggaacggggg ctggtcagcc ctctaaagct cgcaacgttt caagtctcgc
    43021 cctgaaactt ttggacgaga ttaacgaagt ttggctcttt gactgtggag aaggtacgca
    43081 aaatcgcatt ctggaaacca caattcgacc acgtaaggtc agcaaaatct ttattaccca
    43141 tctgcatgga gaccacattt ttggtttgcc aggtttcctt tctagccgtg cctttcaggc
    43201 caatgaagag cagacagatt tggaaatcta cggacctcaa ggaatcaagt catttgtctt
    43261 aaccagcctt cgtgtgtcag gttctcgtct gccctaccgc attcatttcc atgagtttga
    43321 ccaagattct ctaggtaaaa ttcttgaaac cgataaattc actgtgtatg cagaggagct
    43381 ggaccacact attttctgtg ttggctatcg tgtcatgcaa aaggatctag aagggacgct
    43441 ggatgctgaa aaactcaagg ctgctggtgt tccgttcggc ccgctttttg gtaaaatcaa
    43501 aaatggccag gatcttgttt tggaagacgg aactgaaatc aaggcagcag actatatctc
    43561 agcgccacgt ccaggtaaga ttatcactat tttaggagac actcgaaaaa cggatgccag
    43621 tgtgcgtctg gctgtcaatg cagatgtcct agttcatgag tccacttatg gcaagggtga
    43681 tgaaaaaatt gctcgtaacc atggtcactc aactaatatg caagctgcac aagtagcggt
    43741 agaagcaggt gccaaacgcc tcctactcaa ccatatcagt gcccgtttcc tctcaaaaga
    43801 tataagcaaa ctcaagaaag acgctgccac aatttttgaa aatgtccatg tggtcaaaga
    43861 cttggaagaa gtggaaatct agcagtcaca gaaaggataa gtatgcctac tattctcatt
    43921 acgggagcta gcggtggtct agctcaagaa atggtcaaac tcctgcccaa tgaccaactc
    43981 atcttgcttg gtagaaataa ggaaaaatta gcccaactct acggaaatta ttcccatgca
    44041 gaattgattg aaattgatat taccgacgat tcagccctag aagctctggt aactgatctt
    44101 tatctccgct atggcaagat tgatgtcttg attaacaacg ctggttacgg gatttttgag
    44161 ggatttgacc aaattgctga taaagacatt caccagatgt ttgaggtcaa tacctttgcc
    44221 ctgatgaatc tgtctcgtca ccttgcggct cgtatgaagg aaagcagcaa agggcatatc
    44281 atcaacatcg tcagcatggc aggtctaata gctactggca agtctagtct ttactcagcg
    44341 accaagtttg cggctattgg tttttcaaat gctctgcgac tcgaacttat gccctatgga
    44401 gtctatgtga caacagtcaa tccaggtcca atccgaacag gattttttga ccaagctgac
    44461 ccagatggaa cttatcttaa atcggttgac cgcttcctct tagaggcaga tgcagtggct
    44521 aaaaagattg tcaagattat aggcaaaaat aaacgagaac tcaatctccc gattttgttg
    44581 aacctagccc ataagtttta tactctcttt cccaagctag ctgataagtt ggcaggggaa
    44641 acttttaatt ataagtaaaa agaaccaatg tgcaggttgt tgctagccta catattggtt
    44701 cttatcattt ctcaactatc aaactgaact tcttctagta gatagtcgat aaagcgttcg
    44761 cccatcttag ataggctggt tttctcatgc tggatataga ccagctcaat cgggtcatca
    44821 atatccagtg ggatagaaac gatattgtct ccgtttaggt tgctgttcaa aatccctgtc
    44881 gcaatggtat aaccatccaa accaatcaag agattaaaga gggtggcacg gtcactgacc
    44941 acaatggatt ttttgtggtg ttcttgagaa agaatctctt ctgaaaagta gaaggagttg
    45001 tgcgtccctt ggtcatagct gaggtaaggg aaattctcca aatcagacag tttcaccttg
    45061 tctttctttg ccagagggtt ggtcttgctg acaaagatat gcggttgcgc tgtgaagaga
    45121 tggtgggcta gcaggtgatt gtcatccagc atcttggtta aaacatcacg gttgtaactg
    45181 tttaagaaga ggaccccgac ctcactgcgg aagttcttga cgtcgtcgat aatctcccaa
    45241 gtccgagttt cacgaaggaa gagttcgtat ttctccatat cgcttttctt gagcaaagag
    45301 acaaaggcat tgaccacaaa ggcatagtgt tgagacgaaa cgctaaatag ttcgcggtgg
    45361 gcgacaggat ttttatagcg ttcctccaga agctgggtct gctcgacaac ctgacgggca
    45421 taagagagaa actccatccc atcacgggtc aaggtgattc ccttgggatt gcggataaag
    45481 atctcaatgc ccatttcatt ttccaaatct cgcactgcat tggagagact tggctgagtg
    45541 ataaagagtt gcttggctgc ctcattcatg gagccagttt cgacgatttt gataatataa
    45601 tgtaattgtt gaattctcat gtttttattg taccatactt gccttagaat cgctaaagaa
    45661 gataggaaaa taaggagcat tgtgtgagtc tcttcttgaa aaaaacacaa aattttgcta
    45721 gaatgagtct tatgaaaaca ttctatgatg tgcagcaatt cctcaaacga tttggtatta
    45781 ttgtttacat gggaaaacgc ttatatgata ttgaactgat gaagttggaa ctatctcgga
    45841 tttacgatgc agggttgatg gataaattag actatctaga ggcagaagca gttcttcgca
    45901 gagagcacaa ggtagaattg gattatattg agaaaaatgg agaaaagaac taatggttac
    45961 ttggattttg tgggcactta tactagcaat gttggcgtgg atgggcttta actatcttcg
    46021 tattcgccgt gcggctaaaa ttgtggacaa tgaggagttt gaagccttga ttcgtacggg
    46081 tcaattgatt gatttgcgcg acccagcaga attccacaga aaacatatcc ttggtgcacg
    46141 caatattcct tcaagtcagt tgaaaactag tcttgcagcc cttcgtaaag ataaacctgt
    46201 ccttctctac gaaaaccaac gtgcgcaacg agttacaaat gcagctcttt acttgaaaaa
    46261 acaaggtttt tctgagattt atatcctttc ttatggcttg gattcttgga aagggaaagt
    46321 gaagactagc taaccttatt tccaaattag tcgaatgata ggatgaagct attgttttat
    46381 agtataatta atttgtataa aatttaagga gttcttagaa cataaaagaa aagaagaaaa
    46441 atccactttt tgtgggtatc ttgtcgatta ttcttggttt gttatttcca attgtaggcc
    46501 tgattttggg tatcatagga ttggtcttgg ctatttcata ccaaaaagag tcacaattag
    46561 actataaaat agaaaagatt cttaatatct taggaattgt gatttctgta gttaactgga
    46621 ttgtagcaat cgccttaatt tttcgataaa acaaaaaaag ctttagtttt aggctctttg
    46681 tcaactgcag tgggttgaag tcggctaagc tcgagaaagg acaaaattcg tcctttcttt
    46741 tttgatgttc agagcgataa aaatcctttt tttgaagttt tcaaagttcc gaaatccaaa
    46801 ggcgtttcg
//
LOCUS       DAVLUM010000004        44058 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLUM010000004 DAVLUM010000000
VERSION     DAVLUM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.004"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(157..507)
                     /locus_tag="VYN42_000170"
     CDS             complement(157..507)
                     /locus_tag="VYN42_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461318.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(647..982)
                     /locus_tag="VYN42_000171"
     CDS             complement(647..982)
                     /locus_tag="VYN42_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461319.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(1073..2383)
                     /gene="der"
                     /locus_tag="VYN42_000172"
     CDS             complement(1073..2383)
                     /gene="der"
                     /locus_tag="VYN42_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1461320.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(2397..3110)
                     /locus_tag="VYN42_000173"
     CDS             complement(2397..3110)
                     /locus_tag="VYN42_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1461321.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(3107..4003)
                     /gene="dnaI"
                     /locus_tag="VYN42_000174"
     CDS             complement(3107..4003)
                     /gene="dnaI"
                     /locus_tag="VYN42_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1461322.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(4004..5173)
                     /locus_tag="VYN42_000175"
     CDS             complement(4004..5173)
                     /locus_tag="VYN42_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1461323.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTINF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(5174..5647)
                     /gene="nrdR"
                     /locus_tag="VYN42_000176"
     CDS             complement(5174..5647)
                     /gene="nrdR"
                     /locus_tag="VYN42_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1461324.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            5787..6152
                     /locus_tag="VYN42_000177"
     CDS             5787..6152
                     /locus_tag="VYN42_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1461325.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            6157..6852
                     /locus_tag="VYN42_000178"
     CDS             6157..6852
                     /locus_tag="VYN42_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461326.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            6869..7636
                     /locus_tag="VYN42_000179"
     CDS             6869..7636
                     /locus_tag="VYN42_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461327.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(7989..9188)
                     /locus_tag="VYN42_000180"
     CDS             complement(7989..9188)
                     /locus_tag="VYN42_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461328.1"
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMASRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(9185..10078)
                     /locus_tag="VYN42_000181"
     CDS             complement(9185..10078)
                     /locus_tag="VYN42_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461329.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPIQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            10195..10275
                     /locus_tag="VYN42_000182"
                     /pseudo
     CDS             10195..10275
                     /locus_tag="VYN42_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10785..10973
                     /locus_tag="VYN42_000183"
                     /pseudo
     CDS             10785..10973
                     /locus_tag="VYN42_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11388..12005
                     /locus_tag="VYN42_000184"
     CDS             11388..12005
                     /locus_tag="VYN42_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1461330.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(12325..13212)
                     /locus_tag="VYN42_000185"
     CDS             complement(12325..13212)
                     /locus_tag="VYN42_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1461331.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(13361..15244)
                     /locus_tag="VYN42_000186"
     CDS             complement(13361..15244)
                     /locus_tag="VYN42_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1461332.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            15621..17075
                     /locus_tag="VYN42_000187"
     CDS             15621..17075
                     /locus_tag="VYN42_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1461333.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            17056..18021
                     /locus_tag="VYN42_000188"
     CDS             17056..18021
                     /locus_tag="VYN42_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1461334.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(18056..19330)
                     /locus_tag="VYN42_000189"
     CDS             complement(18056..19330)
                     /locus_tag="VYN42_000189"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1461335.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKYQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(19330..20502)
                     /locus_tag="VYN42_000190"
     CDS             complement(19330..20502)
                     /locus_tag="VYN42_000190"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1461336.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(20633..20881)
                     /locus_tag="VYN42_000191"
     CDS             complement(20633..20881)
                     /locus_tag="VYN42_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461337.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(20949..21573)
                     /locus_tag="VYN42_000192"
                     /pseudo
     CDS             complement(20949..21573)
                     /locus_tag="VYN42_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(21635..22084)
                     /locus_tag="VYN42_000193"
     CDS             complement(21635..22084)
                     /locus_tag="VYN42_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1461338.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(22086..22844)
                     /locus_tag="VYN42_000194"
     CDS             complement(22086..22844)
                     /locus_tag="VYN42_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1461339.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(22959..24938)
                     /gene="pknB"
                     /locus_tag="VYN42_000195"
     CDS             complement(22959..24938)
                     /gene="pknB"
                     /locus_tag="VYN42_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1461340.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIILTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(24935..25675)
                     /locus_tag="VYN42_000196"
     CDS             complement(24935..25675)
                     /locus_tag="VYN42_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1461341.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(25690..27003)
                     /gene="rsmB"
                     /locus_tag="VYN42_000197"
     CDS             complement(25690..27003)
                     /gene="rsmB"
                     /locus_tag="VYN42_000197"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1461342.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(26996..27931)
                     /locus_tag="VYN42_000198"
     CDS             complement(26996..27931)
                     /locus_tag="VYN42_000198"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1461343.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(27944..30340)
                     /locus_tag="VYN42_000199"
     CDS             complement(27944..30340)
                     /locus_tag="VYN42_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1461344.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEELVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(30406..30720)
                     /locus_tag="VYN42_000200"
     CDS             complement(30406..30720)
                     /locus_tag="VYN42_000200"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1461345.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(30745..31371)
                     /gene="gmk"
                     /locus_tag="VYN42_000201"
     CDS             complement(30745..31371)
                     /gene="gmk"
                     /locus_tag="VYN42_000201"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1461346.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(31501..33114)
                     /locus_tag="VYN42_000202"
     CDS             complement(31501..33114)
                     /locus_tag="VYN42_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1461347.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(33383..33613)
                     /locus_tag="VYN42_000203"
     CDS             complement(33383..33613)
                     /locus_tag="VYN42_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1461348.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            complement(33851..34948)
                     /locus_tag="VYN42_000204"
     CDS             complement(33851..34948)
                     /locus_tag="VYN42_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1461349.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(34958..35704)
                     /locus_tag="VYN42_000205"
     CDS             complement(34958..35704)
                     /locus_tag="VYN42_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1461350.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(35807..36160)
                     /gene="rsfS"
                     /locus_tag="VYN42_000206"
     CDS             complement(35807..36160)
                     /gene="rsfS"
                     /locus_tag="VYN42_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1461351.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(36173..36673)
                     /locus_tag="VYN42_000207"
     CDS             complement(36173..36673)
                     /locus_tag="VYN42_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1461352.1"
                     /translation="MKMAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(36674..37267)
                     /gene="yqeK"
                     /locus_tag="VYN42_000208"
     CDS             complement(36674..37267)
                     /gene="yqeK"
                     /locus_tag="VYN42_000208"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1461353.1"
                     /translation="MSYQDYINCSREALLEKMVEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(37267..37896)
                     /locus_tag="VYN42_000209"
     CDS             complement(37267..37896)
                     /locus_tag="VYN42_000209"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1461354.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(37948..38259)
                     /gene="yhbY"
                     /locus_tag="VYN42_000210"
     CDS             complement(37948..38259)
                     /gene="yhbY"
                     /locus_tag="VYN42_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1461355.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(38473..39579)
                     /gene="yqeH"
                     /locus_tag="VYN42_000211"
     CDS             complement(38473..39579)
                     /gene="yqeH"
                     /locus_tag="VYN42_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1461356.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAREEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(39582..40172)
                     /locus_tag="VYN42_000212"
     CDS             complement(39582..40172)
                     /locus_tag="VYN42_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1461357.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(40124..41032)
                     /locus_tag="VYN42_000213"
     CDS             complement(40124..41032)
                     /locus_tag="VYN42_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1461358.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESETVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFV
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(41089..41649)
                     /locus_tag="VYN42_000214"
     CDS             complement(41089..41649)
                     /locus_tag="VYN42_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1461359.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            41788..43006
                     /gene="sstT"
                     /locus_tag="VYN42_000215"
                     /pseudo
     CDS             41788..43006
                     /gene="sstT"
                     /locus_tag="VYN42_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            43074..44027
                     /locus_tag="VYN42_000216"
     CDS             43074..44027
                     /locus_tag="VYN42_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1461360.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
BASE COUNT        12346 a        10043 c         8495 g        13174 t
ORIGIN      
        1 gatctaaagc attttatacc aatgttttat aagttgtatt gtattattcc atattcaatc
       61 cactatacaa gatgaatatt tctctcaagt ttcataatca aaataaaaat gactgtatct
      121 atagctccat aaaaaaatca tagatacagt cattttttag ttcctacacc ttcctttatg
      181 cacaccttta gacttcccta gttcccgtct caagtcaagc atttttttga aacagatata
      241 gtctaaccag tcactagcaa aagcgataag tagtaataat agccaaatac cccataactt
      301 gatatctgtc aaatttctca agacgatatt gaaaaacaga actgaaaaaa ctgtccaagc
      361 aaggctaaaa agagcataga gggtgatgta aatccagtaa aaatagtaaa aaattgggaa
      421 aaatttactt tctctattat ccttgtcaat ccagctgaaa aagtaaaaac agggtaataa
      481 gattatcatt ttaaacaagt gttccatcac aagcctcctt ttttaaattg ttttctttag
      541 tttcgttcta ttaaatgtta ttaccaatat aaaccttgga atagcgtgta ataaatgatt
      601 ttagaggtac cataagccac ctcctacaaa tagaaaccga tataaatcaa tgccttccac
      661 ccttagactt ccctagttcc tgtctcaagc gaaacatttc tttgaaacag gaataagtta
      721 accaattcat accaatagct agcagaataa aaagaaacca aatgccccat aacttgatat
      781 ctgtcacatt tctcaagacg gtattgaaaa acagaactga aacaactgtc caagcaaggc
      841 taaaaagaga atagaagggg atgtaaaacc agtaaaaata ataaaaaatt ggaaaaaact
      901 tactatttct gttggccttc tcaatccagt tatcaaaata aaagtacggt gctaaaagta
      961 agaatttaaa caaatgttcc atcaccgaca tcaccctcct tcttttgata gcgttttcta
     1021 ttattttatt atatcaaaaa aatccggaac tgtcattcca gattctactt ttttatttgc
     1081 gttttcttgc gatgagatga atcggtgttc cctcaaaaac aaaggccttg cggatttgat
     1141 tttccaagaa acgcaggtaa gaaaagtgca tgagttcttc ttcattgaca aagatgacaa
     1201 aggttggtgg tttggttgcc acttgggtcg catagaaaat cttgagacgt tttcctttgt
     1261 ctgtcggtgt tgggttgatg gcaatggcat ccatgatgac atcgttcaag acagctgatg
     1321 gaatacgtgt attttgactt tcgctgattt gcttaatcat ctcaggaagt ttgtggagac
     1381 gttgcttggt taaagctgat acaaagataa tcggtgcgta aggcaggtat tggaactgct
     1441 cacggatatc ttcttcccag tttttcatag tgtggttatc tttttcaagc gtatcccact
     1501 tgttgaccac gataatcatc cctttaccag cttcatgggc aaatcctgcg atacgcttgt
     1561 cgtactcacg aatgccttct tccgcattga tgaccatcaa gaccacatct gaacggtcaa
     1621 tagcacgcat ggcacgcata acagagtatt tctcagtatt ttcataaacc ttaccagact
     1681 tacgcatacc agccgtatca atcatggtaa actcttgacc atctgtatct gtaaagtggg
     1741 tatcaatggc atcacgagtt gttccagcaa caggactagc aataacacgg tcttctccca
     1801 agatagcatt gatcaagctt gattttccaa cgttaggacg accaatcaag ctaaacttaa
     1861 tgacatctgg attttcttcc tcatattcat ttggaagatt ttctacgatc gcatctagca
     1921 catcccctgt accgattcca tggacagatg agataggcaa tggttcaccc aaaccgagag
     1981 catagaaatc atagatatca tttctcatct cagggttgtc caccttgttg actgcgagga
     2041 taactggttt gtgggtctta taaagcttac gagctacgta ttcgtctgca tcagtaattc
     2101 cttccttacc agacacgaca aaaacgataa catctgcttc ttccatggca atttctgcct
     2161 ggtgcttgat ttgttccatg aaaggagcat cgacatcatc aattcctcct gtatcaatca
     2221 tgctaaaaga acgattgagc cactcacccg ttgcataaat acggtcacgt gtcactcctt
     2281 cgacatcttc tacaatggag attcgctcac cagcgatccg attaaatagg gttgatttcc
     2341 caacattggg acgtcctaca atggcaatag ttggtagggc cataatttct cactttctac
     2401 aataatttct tctgttcaag attttttcta gttgagcttg gttcagcttg accaaactgt
     2461 tctgctaggc gctgactcca gcttgtggtc gcacgcgccc cagcatagtc agcctgaaca
     2521 cggtcataag cttggattgc ctcagttgac tgttcttggt attcttcctc aaagacaaca
     2581 ttctctagtg gcagtcttgg tttcatatca tgatgttgat ttggcacacc cagtgccatc
     2641 ccaaagacag aataggtgta gtcaggtagg ttaaagagct ctgccacttc ttcagacttg
     2701 tatcgaacca aaccgataat cacaccacca tagcccaagc tttcagctgc caacaaggcg
     2761 ttttgtccag caagagctgc atcgaccgaa ctaatcaaga gaccttccac accttggggt
     2821 tggaaggtgt cggtatgaag tcgggctccc ttttctgctc ggttcaaatc tccgacaaag
     2881 agaaggaaaa cagcagactg gcgaatggct tcttgaggta ccaattcata caaggcatct
     2941 ttcttctctt gacttcgtac cacaatcaca gagtaggatt ggaaattctt ccaagatgat
     3001 gccatctggg ctgctgtcaa aatctcattt aagtctactt ggggaatttc ttgctcttta
     3061 aacctgcgca ctgaagtatg agccttcatc aatttaatgg tttctgtcat cgacggttta
     3121 ctccttctaa acgagtctcc tcagccaaat aacggatgcg ttccatgacc cgtctggctt
     3181 cccaggtttc gtcatttcca tgtttcactt tcgcaaaatg cttctccaaa tcttcaaagt
     3241 tgaagttgga tgtgaaaaag gtcggtaaat tttcctgcat ccgatattgg agaatgacct
     3301 gcaggatttc gtcacgcacc caaacggttg attgctcggc gccaatatca tctaaaatca
     3361 ggacctcaga cagcttaatc tcatccacca aggtcttaac attgccatca ctgatagcat
     3421 ttttgacatc aatgacaaag ctaggatagt ggaggagagt ggatgataca ccacgttttt
     3481 ctgataaatc atgagctagg gcagccacca tgaaactttt acccacacca aagtctccat
     3541 acaagtaaag acctttcaaa ttattggggt aatcgttaac aaattctatc attcttttta
     3601 gaacagttaa gcgctgaaca tcatcacgat aaacatctaa aaaactgaca tttttcaggc
     3661 tagatggaaa attaattaag ttgagacgtt tcttgatagc cgcttctttt tcagctgcga
     3721 ttagttcagg agtttcttca taagaaacat ctgcatagcc atggttcatg actaatatag
     3781 gcttgtagcc tttggcaata taatctgtat ctcctcggag gaatttatct ctctcagtga
     3841 tgtattggtt aaacttggaa atactacggt tcaactcgtc ctgattgagg gattcttgct
     3901 ggacaaaggc cgcaacatca ggatccttca tgattttctg aactaaatct tgatagtgaa
     3961 aacgacttgg ttgacgtttg agtacatctc cgacactttc catctaatca cctccgttat
     4021 ctaattttgc taataattct agggtttggc gttccatctc ttctaattcc tcagcggatg
     4081 acgtattttt atattcagga ttactccatt taggaatatt ggtttttgct ggggcagtct
     4141 gattctgttt ttgtgttttt gctttctgtt ctcgctcacg gatgcgcaag actgcctttt
     4201 ctgccgaatg aatcttttga taggcatagt cattggctac cttcatggca tatttctcat
     4261 tgatatttgc cgaatcgacc ttattaaagg tcaataaaag aatgatattg atgacttcgt
     4321 ccagcaagcc caagccagcc atctgttgca agagttctct ttctgtttgg gtaatggttc
     4381 ccttgcgtgt ttgcttgatt tctgccaaga actgcagggc agttttactt ttggcttctt
     4441 tgataatggt tgtttcctta agactaaagt cagaggaaac tggtttttga gcaatttttt
     4501 cccgcatgcg tttggttgaa ataacctgag aaacagctgt tgacttggcc aattgatagg
     4561 tttcaaacca agtccatttc ttctcctcgg caatagcaaa gaggtttaag acatcggact
     4621 gctcatccgc aaaacgaagt ccatctcgag ccatcagctg gcgaaaatgg tccaagtcaa
     4681 aatcgttggc cactttcttc ttgagaccaa ggtcttcttg actgcctagt tctgccaatt
     4741 ctggaaagac ttgattgagt gagacaggta tttcttcacc atcagcactt tcaactttca
     4801 aatcctccac agctacatcg ccaatctttt tctctaagag tctgcgataa acaggatgct
     4861 ccaagaagtc ttgactagat agaggagcat ggaggactag ctgataaaca tccccctttt
     4921 gatagagggt caagagatta aaagcagata agattttcaa tgattttatc agtctatcca
     4981 tcccaaagtt aagatggttg agaatgcttg aaaaaagata ttcctttcta ccattatccc
     5041 aaaaattgat tgtataaaga taaaggctca gtgcctcctg accgataatc gggaggtagc
     5101 actgtaccag agatgaggta tcttgcgaca cccgattatt ctttagataa gaaaaacggt
     5161 caattggctt catttatctt tcctttttct ttttagagga ctgggtgatt tgttggagca
     5221 agctctctaa ctcactgaca tccttaaaac tacgatagac actagcaaaa cgtacatagg
     5281 taatctcgtc caattcagcc aactcctcca tgacgagtga accaatgtcc tcactttgaa
     5341 tttcattttc atttcgacca cggagtttct gttcgatacg attgactacc atgttgattt
     5401 catcacttga cacaggacgt ttctgggctg agcggataat cccattaaag attttatctc
     5461 tggagaattg ttcccgtgtg ccatcttttt taacaaccac taaggttctt tcttctactc
     5521 gttcgtaggt tgtaaaacgg tgttggcatt cgtcgcactc acgtcttcta cgaatggtgt
     5581 tcccttcttc tgcttggcga ctatcgataa cacttgactt ggtagcccca cattttggac
     5641 aacgcatcct ttccctcctt atcgttttct tttcattata ccatttttta agcgattccc
     5701 aaaacaattc ttctttttgc ttgacaagtt ttttgttttg ttgtattatt taattaagac
     5761 aaaaaggtaa aagaaaggag actaagatgt cctggacatt tgacaacaaa aaacccatct
     5821 atttacagat tatggagaaa atcaagcttc agattgtttc ccatacactg gaacccaatc
     5881 aacaacttcc aaccgtgagg gagctagcta gcgaggctgg tgtcaatccc aataccatcc
     5941 aaagagcctt atcagacctt gaacgagaag gatttgtcta cagcaagcga acaactggac
     6001 gatttgtgac taaggataag gagctaatcg ctcagtcacg caaacaatta tcagaagaag
     6061 aattggaaca cttcgtttcc tccatgaccc attttggcta tgaaaaagaa gaactaccag
     6121 gcgtagtcag tgattatatt aaaggagttt aagcctatgt cattactagc atttgaaaat
     6181 gtatccaaat catatggagc aacaccagcc cttgaaaatg tttctcttga cattccagct
     6241 ggaaaaattg tcggccttct tgggccaaac ggctcaggaa aaacaaccct gattaaacta
     6301 attaatggcc tcttacaacc agatcaagga cgtgtcctca tcaacgacat ggacccaagc
     6361 ccagcaacca aggccgttgt agcttatttg cctgatacga cctatctcaa tgagcaaatg
     6421 aaggtcaaag aagccctaac ctacttcaag accttctata aagatttcaa tcttgaacgc
     6481 gcccatcatc tacttgcaga cctgggcatt gatgaaaata gtcgtctcaa gaaactatca
     6541 aaaggaaaca aagaaaaggt tcaactgatt ttggttatga gccgtgatgc tcgtctctat
     6601 gttttggatg aacccattgg tggggtggat ccagcagccc gtgcttatat cctcaatacc
     6661 attatcaaca actactcacc aacttctacc gttttgattt ctacccactt gatttctgat
     6721 atcgagccaa tcttggatga aattgtcttc ctaaaagacg gaaaagtcgt ccgtcaagga
     6781 aatgtagatg atattcgcta cgagtcaggt gaatccattg accaactctt ccgtcaggaa
     6841 tttaaggcct aagcaaagga gattatttat gttttggaat ttagttcact acgaatttaa
     6901 aaatgttaac aagtggtatt tagccctcta cgcagccgtg ctagtccttt ctgccctcat
     6961 cggaatacag acacaaggct ttaaaaatct accttaccaa gaaagtcagg ctactatgct
     7021 actttttcta gctacagtct ttggtggctt gatgcttaca cttgcgattt caaccatttt
     7081 cttgattatt aaacgcttca aaggtagtgt ctacgaccga caaggctatc tgactttgac
     7141 cttgccagtt tctgaacacc atatcatcac agccaaacta atcggtgcct ttatctggtc
     7201 attgattagc accgctgtat tggctctaag tgctgttatt attctggctt taacagctcc
     7261 agaatggatt cctctttctt atgtgattac atttgtagaa acacatctcc ctcagatctt
     7321 tcttacaggt atatccttcc tactaaatac catttcagga atcctctgca tctacctggc
     7381 tatttccatt ggacagcttt tcaatgaata ccgtacagca ctcgctgttg cagcctacat
     7441 tggtatccaa atcgtcattg gatttattga acttttcttc aatcttagtt ccaatttcta
     7501 tgtcaattca ctggtaggac tcaatgacca tttctatatg ggagcaggta tagccattgt
     7561 taaagaactc atattcatag ctatctttta tctcggaacc tactacatct tgagaaataa
     7621 ggttaatttg ctttaaataa tttttaccta gatatgtaac atactcatag aacaaaagag
     7681 accaggcaaa aagtctttaa aattagaaaa cgcatagtat caagtgttaa aaatccttga
     7741 tattatgcgt tttttgtgag ctgacttatt tcctttcgct atatcgcaaa atgaaataag
     7801 aacggaacga tgggattttg gaattcaaat caatttataa gaatgtttta gaagtaatat
     7861 tatcctattc cagattcagt tcactataca attgagtttt caagcaacct gtttacataa
     7921 tgtgtacata attaggttcg tgattccacc cttttcacct ttaaaaacct cgctttcgca
     7981 aggctcttct atttataaga taaggcacgt ttaaaggttt tccaaatccc taaatcatcc
     8041 gtttgaagaa cgagactagc atacatgcgt ccgataaatc ctgttgctac caccgcaaaa
     8101 atcactgtaa tagcaagtga aatccatgct tctgctcccc ccgcatagcc attaatcgtt
     8161 cgaaacggca taaagaaggt cgaaataaag ggaatataag aaccaatctt caagaggaga
     8221 ttgtcaccag ctgcacctag agctgtcact ccaaaaaaac cacccataat caaaatcatc
     8281 aaaggcgaca aggctttccc tgagtcctca ggacgagaag ccatagatcc taggaaggct
     8341 gccaagacta cgtacatgaa aagactgatc aaaataaaga gcagggtatt cagtgagata
     8401 gcatctccca agtgaaccaa aataccagac tgagccaaga atggcaaatc tttaaagagc
     8461 aaaacggcag ccagaccacc tacaacatag atcccaatat gcgttaaaat cactagaaac
     8521 agagccatca tccgcgcata gaaatagtga cttgccctta tgctagaaaa aacgacttcc
     8581 ataattttgg tgcctttttc actggcaact tcctgagctg ttacacccgc ataggtaatc
     8641 agaatcatat aaagaaagaa tcctaaggca cctgctgcaa ttgtttgaat aaacttttta
     8701 ttttccttgg cttcatcaat cttttctgtg aattgaattg tctgcgctaa gcgtttttcc
     8761 tgctcttgag acaaggaagc agttgaacga ttaagctgat tttgcagttc attgagtgta
     8821 cctgtaacct caaatttaat tccattttca agcgatgttt cgccatgata aactgccttt
     8881 agaacactat cttcttgatc aatggtcaaa taacctttta atttttcttc tttaattgct
     8941 tctttggcac ttgcttcgtc tttatagtcg aagttaacac catttacatt cttcagtcct
     9001 tctgctacag atggcactgt tgtcactact gccactttat tatttttagc catagaagaa
     9061 ccttggatat gcccaattcc tacagagatt cctaaaaaga ggaacggcga aatcaccata
     9121 aagaagaaac tccatgactt gacatgtcga agataggttt ccttgattac aacccacata
     9181 tttctcatac ttccactcct gattctagtt taaagatttc atcgatagtt ggcgcttgtt
     9241 ggtcaaatgt tgcgatatat tgaccttgag tcaagattgg gaagagttcc cttccagcgc
     9301 tctcatcctc caaaatcaat ttccaactgc cttgtttggt caagctcacc tgtttgacat
     9361 gaggaagatt ttccaattct tccttgcttc gttcacttga aacaaagaga cgcgttttcc
     9421 cgtattgatt gcggacatcc tgaattggtc cgtgcaagac cacacggcca tctcggatca
     9481 tcagaatatc gtcacaaagt tcctcaacat tggtcatgac atggtcagaa aagataatgg
     9541 ttgctccgcg ctctttttcc tgaaaaatga cttgtttgag caattctgta ttaactgggt
     9601 ccaatccact aaaaggctca tccaagataa tcaggtctgg ttcatgaatc agagtaataa
     9661 tgagctgaat cttctgctga tttccttttg acagactctt gattttatct gtcagctttc
     9721 cttttacttc caacctcttc atccattgag ggagtttttc tttgacttct ttggcatcca
     9781 tgccttttag agtcgccaag tagcgaactt gttcaagaac tgtcaattta ggcatgagac
     9841 tgcgttcttc aggcagataa ccaatccgag cataggtctc ctgacgaata tcctgaccat
     9901 ccagaccgat ttctccctga tattctagga attttaaaat actatggaaa atcgttgttt
     9961 ttccagcacc attttttccg actagtccca aaatacgacc tggtcgcgct tgaaagtcaa
    10021 taccaaacaa aacttgcttg gatccaaaac ttttctctag acttcttact tctagcatct
    10081 ttcacctccg aaatttcttg cactcattat actccttttt gatagccttt acaatgtttt
    10141 ttgtccattt ttagaagact attgctgtgt aaaatatggc ctggagcact tttatactca
    10201 atgacaatca aagagcaaac taggaagcta gccgtagact gctcaaagta cagctttgag
    10261 gttgcagata aaactgacga agtcagctca aaacactgtt ttgaggttgt ggatagaact
    10321 gacgaagtca gtaactatat ctacggcaag gcgaagctga cgtggtttga agagattttc
    10381 gaagagtatt agtgataaat ccattataca gcagcaaact taatttatac cttccgctcc
    10441 tcaactgtct atttttaatc ctgaattgtt atttgagtaa ctcctttttc ctcgtaaagt
    10501 tttcttcctc taaaacttct ggaaaaaggc taatagtttc agacaacatt tttataagaa
    10561 acaagttcat ctgtcatttc aagaaggagt aatcctttat ctactaatgg acggaacaga
    10621 attcaaccgc ttgtccgata tgttttctaa ggattatata gtaaaatgaa ataagaacag
    10681 gacaaattga tcaggacagt caaattgatt tctaacaatg ttttagaagt agatgtatac
    10741 tattctagtt tcaatctgct atatctatta tgcacaccac tataggatct aataaaaatc
    10801 acaacaagtt cattcataga tggttacctc agggaactaa gaaaacgact acaaaggaag
    10861 tcgcattcat cgaaaagtgg attaacaact atcctaaaaa atgcttgaac tacaagtccc
    10921 ccagagaaga cttctggatg actaacttga acttgaaatt tagcaataat taattcacca
    10981 tctaactata tttagtaatt atttcagaac tgattaatat taaaattaac taacaattca
    11041 aaggattcat actagccata aattacgtcc atcagagaga gactcttact acttttagat
    11101 tttagtcttt ctagcttcag aatacatcta aactttaggg aaaatgacta ttcgaaaacg
    11161 cgaatgcctc aaaattatct cagataagct attcgaaact tagaatgctt ttaaatttat
    11221 ggaattgcga ttattcgaaa cctagaatgc atataacctt tagttgacag acctattcta
    11281 agtctcgaag ggctatttac tttctattcc ttatcaaaaa agactcattc cccctttctc
    11341 ctccaaaata tggtatagta gaaatatact atctatgagg agtttacatg tcacaggata
    11401 aacaaatgaa agctgtttct ccccttctgc agcgagttat caatatctca tcgattgtcg
    11461 gtggggttgg gagtttgatt ttctgtattt gggcttatca ggctgggatt ttacaatcca
    11521 aggaaaccct ctctgccttt atccagcagg caggcatctg gggtccacct ctctttatct
    11581 ttttacagat tttacagact gtcgtcccta tcattccagg ggccttgacc tcggtggctg
    11641 gggtctttat ctacgggcac atcatcggga ctatctacaa ctatatcggc atcgtgattg
    11701 gctgtgccat tatcttttat ctagtgcgcc tatacggagc tgcctttgtc cagtctgtcg
    11761 tcagcaagcg cacctacgac aagtacatcg gctggctaga taagggcaat cgttttgacc
    11821 gcttctttat ttttatgatg atttggccca ttagcccagc tgactttctc tgtatgctgg
    11881 ctgccctgac caagatgagt ttcaagcgct acatgaccat catcattctg accaaaccct
    11941 ttaccctcgt ggtttatacc tacggtttga cctatattat tgactttttc tggcaaatgc
    12001 tttgacacgt aaaaaatccg tttggtttcc caagtggatt tttaaagcgt agattaacta
    12061 tagcttgata ctaaatatac tttggtatgg aaattatgca tatttttcga tagtgaggcg
    12121 aggacttacc tagcctttcc gccgtgatag aaacacctga aatctaatgg tttcaggtat
    12181 tcggaaactt tgagacacta ggctcaaagt ttaggtatgg aatttcgaag aaagtcgcta
    12241 ccgtccgtaa tcacttaagg aaaggctcaa aaatattgtt ttcaaccaca aaatccgttt
    12301 ggtttcccaa gcggattttg tgctttattt tgaaacttct tttgcaagaa caaagttccc
    12361 aagtgtggca gaaccatttc ctgcgactgc tggcgtcacg atatagtcac gcacatctgg
    12421 tactggtagg taaccattaa gaagagatgt aaatttctca cggacacggt ccagcatatg
    12481 ttgttgagcc atgacccctc caccaaagac aatcacgtct gggcggaaag tcactgtcgc
    12541 attaaccgca gcttgagcga tatagtaggc ttgaacatcc caaacagggt tgttgagttc
    12601 aatattttcc ccacgtacac ctgtacgagc ttccaaactt ggaccagctg cataaccttc
    12661 tagacatccc ttatggaaag gacaaacacc cttaaactct ttttcaatat ccattgggtg
    12721 tctagcaaca taataatgac ccatttcagg gtgacccaca ccaccgataa actcaccacg
    12781 ttggatgacg cctgcaccga tacctgtacc gattgtgtag taaaccaagt tttcgatacg
    12841 accaccagca ttgttacggg caaccatttc accgtaagca gagctgttta cgtctgttgt
    12901 gaagtacatt ggcacgttta gggcgcgacg aagggcacca agcaagtcta catttgccca
    12961 gtttggtttt ggagtcgtcg tgataaagcc ataagttttt gagtttttgt caatatcaat
    13021 cggcccaaat gaaccaactg caagaccagc aaggttatcg aattttgaga agaactcaat
    13081 ggttttatcg attgtttcga ttggagttgt tgttggaaat tgtgtttttt ctacaacgtt
    13141 aaagttttca tcaccgacag cacagacaaa ctttgtaccg cccgcttcca agcttccata
    13201 taattttgtc atgataaacc tcttgttttt attttcttta ttatagcata cttcgaaagt
    13261 ctaaatgtct ctatttttta gattttcctc tgtaaatctt actatctaat aaaaacgaac
    13321 aaacatgtca tttgttcgtt ttcacattag agaggattga ttagattttc acttcgatca
    13381 cagcatcccc cttcgaaact gaacctgttg cgactggagc tactgaagcg tagtcagctg
    13441 tatttgtaac gataaccatt gttgtatcat caagtccagc tgcagcgatt ttgtttgagt
    13501 caaatgttcc aagaacatcg ccagctttca ccttattacc ttgagcaact tttgcttcaa
    13561 aaccgtcacc gttcatagat acagtgtcaa taccaacgtg aatcaaaact tcagcaccat
    13621 ttcttgtttt caaaccaaaa gcgtgccctg ttggaaaggc aattgaaact tcagcatcag
    13681 ctagtgcata gaccacgcct tgacttggtt tcacagcgat accttgtccc atagctccac
    13741 ttgagaagac tgggtcattg acatcagcaa gagcgacaac atcaccgacg ataggagtta
    13801 caagtgtttc attttgaaga gctgctggcg caacttcttc tttttcttca gccacttcag
    13861 cttgttttgc agctgcagtt gcgtctactt catcttcgta accaaacatg taagtaagag
    13921 caaaaccaag ggcaaatgat acagctacca taagaaggta ttgtggaagt tgtccgttac
    13981 caacataaag cattgtacca gggatgatgg tgataccatt accagtacca gcaagtccaa
    14041 ggatagaagc caatccacca ccgattgcac cagcaatcaa tgaaaggaag aatggtttac
    14101 ggaagcgcaa gttcaccccg aagatagcag gctctgtaat acctaggaag gcagaaagag
    14161 cagccgggaa agcaagtgtt ttcagttttg gattttttgt tttaacacca accgcaacag
    14221 tagcagcacc ttgagctgtc atagcagctg tgatgatagc gttgaatggg ttagcatggt
    14281 cagcagcaag taattgcact tcaagcaagt tgaagatgtg gtgcacacct gacacgacga
    14341 tcaattggtg aaccccacca atcaagaaac caccaagacc aaatggcatg ctaagaatcg
    14401 cttttgtagc aataaggatg tagttttcaa caacgtggaa aactggtcca atgacaaaga
    14461 gtccaaggat agacatgacc aaaagtgtca cgaatggtgt taccaagagg tcaatgacat
    14521 ctggaacaac cttgcggaca gctttttcaa atttagctcc gacaaccccg atgatgaagg
    14581 ctggaagaac ggaaccttgc aaaccaacaa cagggatgaa accaaagaag ttcatcgctg
    14641 ttacttcacc accttgagca actgcccaag cgtttggaag tgagccagag acaagcatca
    14701 taccaagaac gataccaacg gcaggatttc caccaaatac acggaaggtt gaccacacaa
    14761 ccaaacctgg caagatgatg aaggctgtat ctgtcaagat ttgtgtgtaa gttgcaaagt
    14821 cacctggaag tggcatttca agagcgttga aaagaccacg cacacccatg aagagacctg
    14881 tcgctacgat aactgggatg attggaacga aaacatcacc gaaagtacgg atagcacgtt
    14941 ggaaccagtt cccttgttta gcaacttctg ctttcatgtc atccttagat gatgttggta
    15001 agccaagtac aacaacttca tcgtacattt tgttaactgt acctgtacca aagataattt
    15061 ggtattgccc tgagttaaag aaagcacctt gaactttttc caagttctca atcacttctt
    15121 tattgatttt ctcttcatct ttgaccatga cacgtagacg agtcgcacag tgggcaacac
    15181 tattgacatt ttcacgtccg cccaaggcat cgatgacttt ttttgcaatt tcctgattgt
    15241 tcatttgcaa aaatctcctt atataacatt ttgttcttgt ttgaaagcga ttttattcgc
    15301 ccttacgact attattttat catgttttaa aaatatgtca agcgttttgc agaaaaaata
    15361 ttctatccac ttagtgggca agttttagat tgattgtttt tgactgtttc atcaggaatt
    15421 ccttgaaaaa taagtttgaa accttggtta aaaagtcttt tatttcatta tctttcacat
    15481 tttcgtaaaa atttgattga tttcctgtat ttattttatg ataatcgttt gacagttttt
    15541 cctctttttt aacataaaag gcttgcattt tttatcgaaa acagttacta ttaaaagtga
    15601 taagattttt ggaggaatga atggaatgga caactgagcg tcgttacaga ctttatcaag
    15661 attggacgca agaagaaatt caacatataa aggaaaatat ggcacaatct ccatggcata
    15721 ctcattacca tgttgagcca aaaacaggac ttctcaacga cccaaatggc ttttcttact
    15781 ttgatggcaa gtggatcctc ttttaccaga attttccttt tggtgcagcc cacggtttga
    15841 aatcttgggc acagctagaa agtgatgatt tggttcactt taaagaaact ggaatcaaag
    15901 ttttaccaga tactccatta gatagccacg gtgcctactc tggttctgcc atgcaatttg
    15961 gcgataactt attcctattt tatacaggaa atgttcgcga tgaaaactgg atccgtcacc
    16021 cataccagat cggtgctttg atggacaagg agggtaagat tacaaagatc gacaagatct
    16081 tgattgacca gccagcagac tctactgacc acttccgcga tccacaaatt tttaacttta
    16141 aaggtcaata ctatgctgtc gtcggtggac aggacttgga gaaaaaaggc ttcgtccgtc
    16201 tctacaaggc tgtcaataac gactacacaa actggcaagc agttggcgac cttgactttg
    16261 ctaacgaccg tactgcctac atgatggaat gtcctaatct ggtctttgta gaggaacatc
    16321 ctgtccttct ctactgtcca caaggattgg ataagaaagt tctagactac gataatatct
    16381 ttccaaatat gtataagatt ggggcttcct ttgaccctaa aaatgccaaa atggtagatg
    16441 tgtctcaact tcaaaacatg gattacggtt tcgaagccta tgcaactcaa gccttcaacg
    16501 ctcctgatgg gcgtgctcta gcagttagct ggcttggttt gccagatgtt tcttacccat
    16561 ctgaccgttt tgaccaccaa ggaaccttct ctttggtcaa ggaactcact atcaaagacg
    16621 acaagctcta ccagtatcca gtcgctgcta ttaaggacct tcgtgcttct gaagaagcct
    16681 tctcaaaccg ttcccaaacc aagaacactt acgaacttga actcaacttg gaagctaata
    16741 gccagagcga gattgtctta cttgctgata aagaaggtaa gggactttca atcaactttg
    16801 accttgtaaa cggtcaagtg acagtggatc gtagccaggc tggagaacag tatgcccaag
    16861 aatttgggac aactcgttct tgccctatcg agaatcaggc tactactgct acaatcttca
    16921 tcgataactc tgtctttgaa attttcatca ataaaggaga aaaagtattt tctggtcgtg
    16981 tcttcccaca tgcggaccaa aatggtatcc tgatcaaatc tggaaaccca actggaactt
    17041 actatgaatt agattatggt cgcaaaacta actgatgtcg ccaaacttgc aggcgtcagt
    17101 cctactaccg tttctcgggt tatcaataaa aaaggatatc tatctgagaa aaccatccaa
    17161 aaagtcaatg aagccatgag agaattaggc tataaaccca acaacctggc tcgtagtctg
    17221 caaggaaaat cagctaagtt aatcggcttg attttcccca atatttccaa tgttttctat
    17281 gcagaattga ttgataaatt ggaacaccaa ctcttcaaaa atggttacaa gaccatcatc
    17341 tgcaacagtg aacatgattc tgagaaggaa cgcgaataca tcgaaatgtt ggaagccaat
    17401 caggtagacg gcatcatttc tggtagtcac aacctaggaa tcgaagacta caatcgtgtg
    17461 acagcgccga ttatttcctt tgaccgaaac ctatcgccag acatccctgt tgtctcctct
    17521 gacaactatg ctggtggggt tcttgctgcc caaaccttgg tcaagacagg tgcccagtct
    17581 atcatcatga ttacagggaa tgacaattcc aattcgccaa ccggactgcg ccacgctggt
    17641 tttgcatccg tactcccaaa agctcctatt atcaatgttt ccagtgactt ttctcccgtc
    17701 agaaaagaaa tggaaatcaa gaatatcttg acccgggaaa aaccagatgc catttttgct
    17761 tcggatgatt tgacagctat tctggtcatt aaaatcgctc aagaattggg catttctgtc
    17821 ccaaaagagc tcaaggtcat cggctatgat gggacctact ttatcgaaaa ttactaccct
    17881 caattggcta ctatcaagca acctttggaa gagattgctt gtctcactat tgatcttctc
    17941 ttgcaaaaga ttgaaggcaa ggaagtcgcc acaactggtt acttcttacc agttacgcta
    18001 ttaccaggaa aaagtattta aacacaagaa aactcagacc gattcgtctg agtttttatg
    18061 atcttaaatt ttcgagatag cgctgggctg tctctaggtt aaaggtttta tctgagatga
    18121 ggcgctctac taggggagca acttcagatt cactagcccc agctaggaga gctagggatt
    18181 tggcctgtag tttcatgtgg ccttgctgga tgcccgtact taccaaggct ttgagggctg
    18241 caaaattttg agcaagaccg atggacacga taatctgggc taattctctg gcagaaggat
    18301 ttcctagtag atcatgactg agagctacac gtgggttgag gccgatagag ccacccttag
    18361 tcgctacagg catgggcagg gtcatctcac cgaccaattc ttctctttca aggtccagcg
    18421 tccagcagct aagaccttga tagcgtccat ctcgactggc aaaggcatgg gccccagctt
    18481 cgatggcacg ccagtcatta ccagtggcaa tcaaaatcgc atcaatacca ttaaaaattc
    18541 ctttattatg agtagcagct cggtaaggat cagcctgcgc aaactgacta gccaacgcaa
    18601 ttttctccgc aatctctcgt ccttgatact tttggcggct caagtagcga aaggcgatgc
    18661 gacagcttgc agtcaccaga gaatcagtcg cgtagttgga caggattccc atgagactct
    18721 gtccctgact gagttcttct aagactggtt tcaaggcttc cagcatggtg ttgagcatat
    18781 tggcacccat ggcttcctgg gtatcgacat gaatataaac aacgagaaag tctggttcgc
    18841 cttttatctg ctcgacatgc agatcacgcg ccccaccccc acgtttaacg atagaaggat
    18901 aggcttgatt ggcaagctcc aagagctccg ctttcttgct ggcaatcttc tcttgcgcta
    18961 gtttaggatt agcaacttga taaagggcta cctgcccaat catctggcgc tgatggactt
    19021 gtgcagtaaa accacctgca cgcttgatga ttttgctggc atagctggcc gccgcaacca
    19081 cagagggttc ttctgtcaca tagggaacgg tgtattcctg accgttgaca agtacctccg
    19141 gaaccagcga ataaggcaga gaaaaagttc ccaccacatt ctcactcagc tggtctgcca
    19201 cagtcacact catctgttca tccttctcca gactagcttg tctctcagga ctaaggagcg
    19261 cctgagcttt tagcagctcg aggcgctctt ggtatgattt tttagaaaat ccattccaac
    19321 ttatcttcat tatttttcaa ccttgctata acggcgttgg tggtcaagaa tttcaaccaa
    19381 ggcaaaatct tgattttcat agccagcaaa ctgggcagag tttgtttcat ccaagtttac
    19441 ttcctcaaaa aagacctttt catagtctgc aacggataag gcagttcgtt ggttgagctt
    19501 gttcaaacgg tctttatcca aataagcttc atatccttca accaattcac cactgaagaa
    19561 ctcagccaca gctccacttc cgtaactata aagggcgatt ttatccccag ctttcaagct
    19621 atctgtattt tccaagagag acaaaagtcc aaggaaaagt gaacctgtgt agatattccc
    19681 caccttttga ctgtagagaa tagactggtc aaaatgcttt tgtaagaggt cttttttctc
    19741 ttgaggcagg ctcttatcca tgattttttt caagcctttt agcgctaatt taggataagg
    19801 caagtggaaa caaacagccg caaaatcatc caaagtaagc tggtagcgtt tttgatattc
    19861 aagccaagtc gttttcaaac tatccaagta ttgttgggta gaatagacac catttacata
    19921 aggagttgtc gagtaatttg gtcgccagaa atccatgatg tcacgggtct gagctacatt
    19981 gtcattatta aaggccatca tgcgtggatt ttgtgtaatc aacatagcta cacttccagc
    20041 accttgagtt ggttctcctg gagtttcaat accgtatttg gcaatatcac tggcaatgac
    20101 caagaccttg gactccggag aattttccac atgcaatttg gcataatgga gggcagcagt
    20161 cgccccatag caggcttctt taatctcgaa actacgagca aagggctgga tgcccagcaa
    20221 gccatgcaca aagacggccg cagccttact ctggtcaatt cctgactcgg tcgccacaat
    20281 gaccatgtca acttcttgtc tttcttgctc agttaaaata gagtcactag cactggccgc
    20341 caaggtcacg atatcctcag ttaggggcgc aatactcaat tccttgagta agagtccttt
    20401 acttaatttt tcagggtcaa ttcccctcgc ttctgctaag tcttgtaatt tcaagacata
    20461 ttgactggtc gcaaaaccaa tcttatcaat accgattgtc atatttacct ctgttttatc
    20521 attcatgtaa aaaatcgttc tatactattt tatcacaaat ggcagtaaaa gagagaaaaa
    20581 agacttgatt caccaaatca agcctcttat tggtcatcat tttaaagaat gattagttgc
    20641 tagagagttc accgatataa gtagctttat aagctccatt cacagttatc agctcctgga
    20701 ggatcaaatt tcctgagtaa gtccttccca tctcatctac aaatttttga taaaactgac
    20761 tggtcggaat ttctctgaca tccttatcaa atgtcttatc aagtgtttta ctaaccttct
    20821 cagcaatcaa ttgatgctct tgccatccac tttgaaactc tgagcccgaa ctagaaacca
    20881 tgactgggat aaacaacaag gtcagtagac ttacagacaa taaggaaaat agtagacttc
    20941 ctgcaaaact agaatcctag ttcatgattg ataataccag caatcaaatt cattcgtaat
    21001 ccgaagcgtt tacgatgatt tcgataggtt gttgaaaata ttttaaacgt ttttactttg
    21061 gcaaagatgt tctcaacctt gcttctctcc ttagatagcg catggttata ggctttatct
    21121 tcagctatta gcggcttgag tttgctggat ttacgtggag tttgtgcttg aggatatatc
    21181 ttcatgggcc cttgataacc actgtcagcc aagattttac cagcttgtcc gatatttctg
    21241 cgactcattt tgaacaactt catatcatga caatagttca cagtgatatc caaagaaaca
    21301 attctccctt gacttgtgac aaccgcttga gccttcatag cgtggcattt ctttttacca
    21361 gaatcattcg ctaattcttt ttttagggcg attgatttgt acttccgtcg catcaatcat
    21421 taccgtgtcc tcagaactga gaggagttct tgaaatcgta acaccacttt gaacaagagt
    21481 tacttcaacc cattggctcc gacggcttaa gttgctttcg tgaataccaa gatcagccgc
    21541 aatttcttca taagtgcggt attctcgcac atatagaaag cgttgttaat ttatttatct
    21601 catttttcag aaaattcttt tatttctgta aagtctacga tactcgatgt gtctttatat
    21661 aatgatacag tctgagaatc actgttccgc tagccattcc aatagagatt accagagcca
    21721 acatgacaac caaggtcgca cttgccagtg ctttattata gtcccctgtc acaaaaaagg
    21781 cagttgttcg gtaggagaga taacctggaa ccagcggtgc caaaatggcc aagataaaga
    21841 ccacagcagg tgtcttataa agaatactta aaatctggct gacacaagaa ccaataatgg
    21901 ctgcaatgaa ggtagctaca atgacattgg tcggttcctt gagcaagaga tagattagcc
    21961 agacagtcat gcccaaaatc cctccaggta agagcataga ccgttgcaca ttgagtacga
    22021 ttaaaaaagt gataatggca agaaaacttg ctactgcttg taataaaaag gttgttagtg
    22081 tcatattagt tcatcaatac caaggcgaca gaagttcctg cccctaaagc gagggtaatg
    22141 agcagggatt caaacatctt actcatacca gagtttatgt ggttggtcat aatatcacgg
    22201 accgcattgg tcaaggcaat acctggtaca aacggcatga ccgcaccagc tataatcaaa
    22261 tctgccgttg aaggaaaacc tgtgtagcga gcccaaaact gggcaattat cccaaagaca
    22321 aaggctccag caaaggctgt cacaaaggga attcggataa atttttccac atagagggaa
    22381 aaggcaaaac caaataaggt cgccactcct gccccaagtg cgtcgtagat atttccgcta
    22441 aacataactg aaaagaaagg agcactaaag gtcgcagcca gagttacctg caacttagta
    22501 tagggaaggg gttgagcttg caaggccgtc aattgcttaa aggctgtttc taagtcaatc
    22561 tgccccccaa ctagctgacg agaaatctgg ttcacatcgc agactttttc gatgttataa
    22621 gaagaggagg tcacgcgctt catgcgcgaa atattggtat tttcaataga gaaaaagata
    22681 gcggcaggca tggcaaggac attgcaatcc acaatcccct gcgaatgcgc gattcgaatc
    22741 atggtatctt ctacacgatg gatttctgag ccacttttaa ggagaatagt ccccgctagc
    22801 ataatcacat caatgacggc atttaattct tttgattctt ccatgctttc ctccttttat
    22861 caactccctc tattctatca caaatctgga ctcaaaaaaa atctttgcca tgaaatcatg
    22921 acaaagattg attactcatt ttgattatcc atctactttt aaggagtagc tgaagttgtt
    22981 ttaggtttgt agattgaaat cttgactcta gtcttattta ggtctacctt ttcacctgct
    23041 ctaggacttt gttcaacaac catgccttct gcactacctg caggcgctgt cgtcacttct
    23101 acaacttcta tattagcttc cttaatccca acaatttgaa tcaaattgtt cttagtaaac
    23161 tccaagctgg aaccaatgta actcggcatg gcaacacttg taactttttt agctactgtc
    23221 aagacaattt gagtaggttt actcacatca taagtcgttc cggcacctgg actttgtttc
    23281 ataatcgttc ctggttcgct ttcgctggac tcttcttcct ctatcttaat caaattctca
    23341 ggaaccttct tctgcttgag ttctgagatt acttctgtag agttccgtcc aatatagttc
    23401 cctaattgaa tcgtcgtagc ttttttagct actgtcaaaa taatttgagt tgccttgctc
    23461 aagtcatagg tcgtaccttc tggtagactt tgcttcagga ccgttccagc ctcactctca
    23521 ttcgactctt cttcctcaat tttaatcaaa ttatctggaa cttttttctc ttttaattcc
    23581 gcgataacat cagaagattt ccggccgaca taattactaa tttggaagga ttgtttgcct
    23641 gatgagacaa ccagattaat tttcgttcct tcttttcgac cagttccagc gccaggatct
    23701 gtacggataa tccgcccttc ttccaccttt tcactagcct ctgtcttctc ctcaccaatc
    23761 tcaaaattgg cttttttgag cgttgccttg gcctctgcaa ctgtctgacc tgccacatct
    23821 ggaatggcaa tggttgcagg agttctggat agtatccaaa taagagaagc tgccaccaat
    23881 acaaggctgg ccaacaaaat caggtaacgc atcttaaatc tatgtttttt cggtgcttgt
    23941 ggttggtaag tttcctctgt cacagcctgg cttgggtttt tgattgattt gtgttctgtc
    24001 tgcgcttgaa ccttaggaat agatgtcaag gtactctgag aaaccttcgg caaggtcttg
    24061 gtatctgcct tgctcgtttc atcaaagatt aacttacttt catttctacg attgtaggac
    24121 aagctactag acaagtctac atacatctct gaaaccgagc gatagcgatt ggtcaacttt
    24181 ttagcagttg ccttgataat aacattttct aaagcctgag gtacagatgg attttctgca
    24241 ataacggacg gcaggggttt ctggaaatgc tggagggcaa tggtcaccgc gctatccccg
    24301 tcataaggga tatggcctgt caacatctca tagaaaataa tccccatggc atagatatca
    24361 ctctgcacag tcgccttcga accacgcgcc tgctctggtg acaagtaatg aactgagccc
    24421 aacatcgagt tagtctgggt cagacttgtc tctgcaaagg ctacagcaat cccaaagtct
    24481 gtgaccttgg ccgtcccatc tggtgtcaaa aggatatttt gaggtttcaa gtccctgtga
    24541 acaattcctc gagtatgggc caagcgcata gccaagagaa tttgtcccat gatacggact
    24601 gcttcttcat tagaaagagg ataatgttcc ttgatatagc gtttgaggtc tagtccagca
    24661 acatactcca ttgcaagata ctgttgaccg tcttcctcac caatatctgt tatccgaacg
    24721 atatgaggat ggtctagatc tgccatagct ctcgcttcac gctgaaaacg agctacagct
    24781 atcgggtccg tctggtagtt ggtcctcaga accttcactg ccacttcttc cccatctaag
    24841 attaagtctt tggctaggta gacatccgcc atgcctcctc gaccaatctg tttgacaatc
    24901 cgatagcgtc cggcaaaaat cttgccgatt tggatcattc tgcatcctcc tcgttcatag
    24961 aaacaagggc aaccgtaatg ttgtctaaac ctcctgcatt gttagcaaaa cgaacaagtg
    25021 tctccgtttt atctgctaaa ggaatatcac tggttacaat atcacgaatc tcactgcctg
    25081 aaatcatgtt ggtcaagccg tcactattga gcaagagata gtcacctgac tcaaggataa
    25141 ctgtcccaaa atcaggctga atttcatctt tttgcccaat agactgggtg ataatatttt
    25201 tttgcggatg agcttctgcc tcttctggtg tcaattgacc agccttgagc aattcattaa
    25261 ccaaggaatg atcgctcgtc aactgatggt attcttctcc acgaatcaag ccgatacgcg
    25321 aatcaccaat atgagcatag atagcctgat tatcaataat agcaaggact tccaaagtag
    25381 ttcccatgcc tctgtaagct tcatcctgac caagctggtg aatcttttga ttttcaattt
    25441 ctaggtaatg ggcgaaccat tcacgcactt cattgactgt atcgatctgg gtatcaaccc
    25501 aagctacacc caggtctgtg accgccattt cactagcgat attccctgca cgatgacctc
    25561 ccatcccatc agctaaaata atcatggtac gtccagctct attgacatag tggttgacat
    25621 agtcttggtt atttgttcgt ttctgaccaa catctgttaa taatgaaatt tccatgtgtc
    25681 agttccttcc taatccgata tcttgcgaaa ttgactgatg aagaatccat cacttccata
    25741 caattcaggt gtaatgagga tacagccgtc tttcatgata tccttacatt catgttctag
    25801 ttttacctgc tcgaactcgg gatgactctc taaaaaggcc ttaacaactt gaaaattctc
    25861 ctctgagacg atagtgcagg tgctataagt tattatacca cctttgccta gtatttgaca
    25921 aacactacct aatatttcta actgaatttc ctgcaaggac gcgaaatctg ccgtttcttt
    25981 attgtatttg atatctggtt ttcggcgcaa aagaccgatt cctgaacaag gagcatccac
    26041 caaaatctta tcaaaggaat cctggtcaaa aaactcatgc acctttctgg catccaattt
    26101 ttgagtttga acccgatctg caactcccag acgttgggca ttttcttgaa ttaaatccaa
    26161 cttgtggtcg tacaagtcca gagcagtaac ctgacctgtc gtaagataag aggctatatg
    26221 ggctgttttc ccacctggag ccgcacaggc atcaagcact cgctcatcac cttgtaaatc
    26281 aagcgtcgga gcaaccagct gactggactc gtcttggatg gtaatggctc catccgcaaa
    26341 caaattatgc cctgcaaaat gcccctgctc cttaaccaga ccagtggttg ctaaaagaga
    26401 atcattcgcc tccaacaagg cttggatttc ctcttttcga cttaggtctg ttacacgaat
    26461 actggctttg tttcgcacta acaggctttc aaagatggct tttgctctct cctctccgta
    26521 ttcttccttg agtttggcaa ctagccaaac tgggagagaa taggcaatgg agtcacgctt
    26581 gttttttcgc ttgatgctag caatatctgg ccagccttca cgcaagatac ggcgaaggac
    26641 agcgttgacc aatttttcac tgcctttttt acggagtttg gctaattcca ctgcttcatt
    26701 gaccacagca tgatctggaa ttttgtccaa atagcggagt tggtaggcac tcatgagaag
    26761 aaggacatag agccagctgt ctaactggtc tctgtcttcg ataaagtggg ataggtacca
    26821 ttccagagtc agtttacggg ctaccgttcc atagactagc tcggtcacta agcccttgtc
    26881 tgctgcagag agctgactcc ccttgaggtg tttatttaag gcaatatttg aatatgcttg
    26941 attcacaaaa acatcctcta gcactgctag agctaaactt ctagccgttt ctactttagt
    27001 caccaaatcg ttctcctaca gtcaatgtac gtccaactcc attgaggaag gaagcaatgt
    27061 ccatcttagg cttaccagct ggctgcactt gtttgaggga tagagcccct tcagccgttg
    27121 cgacaatcaa ttctttcttg ccgatagaga gaatctcacc tggatttccc tgaccttcta
    27181 ctggtagggc ttcataaatc ttaaagcggt cgcccttaag gaaagtatgg gcaacaggcc
    27241 aggggttcat tccacgaatt tggttaaaga gttgacgatt ggttttgttc cagtccagtt
    27301 tttcttcctt tggctttata tttggagaga aggtaacctg actcgtatcc tgcggttcag
    27361 gtttgatatc accagcaata taggcaggca gagtgtccaa aagcaaatca caaccaacta
    27421 gcgccaattt ttcaaacaag gtgccaacat tgtcctcatc tgtgatcgga atgctgcgac
    27481 gagaaatcat atctcctgca tccatttcct taaccatttc catgatggtc acaccagctt
    27541 cctcatcccc ttgaatcaag gcataatgga taggcgcacc accacggtgt ctaggaagga
    27601 gggaggcatg aacgttgaca gcaaagtcca tgctatcaag gagtttgctt gggagaaact
    27661 gcccaaaagc agcagtcaca attccatctg ctcctagctt cataagatct tccatctctg
    27721 gacttccaga taatttttca ggttggtaga tagatagtcc tgcttccttg gcagcctgct
    27781 tgactggggt ttcttggata acttttttac gaccaacagc acggtctggc tgggtcacaa
    27841 cggctagaat ttcgtaacgg tcatctgtca aaagtccttt taagactgtt gctgaaaagt
    27901 cgggggtccc cataaagatt agttttgtca tatcttctcc ttcttataaa aattgctgcg
    27961 gctcatggtc aatgctgaga cggagctcac tattttcccg ttcttgagtc aaggccaaga
    28021 cctggttgag ggtcggcccc agctcatctt ctaaacggta tttaattaaa atctggtaat
    28081 gatagaggtt gtgggtacgg gcaatcggtt ttggcgttgg ccccagaatg ggactggtct
    28141 ctgacaagcc tgaccgcaaa atgttcatga cttcataggc acgtttgaaa acctcttctt
    28201 ctttcttgtg agaaagggta ataccaatcg tgaaatagta aggtggatag ccgagttgtc
    28261 gtctgattcc catttcatag gcataaaagc cttcgtaatc ttgatccttg gcaaatcgaa
    28321 tagcatagtg ctgcgaattg taggactgta tcaagacttg acctgctttt tcagcccgac
    28381 ctgctcgacc tgccacctga gtcaagagct ggaaggttct ctcagaagaa cggaaatcag
    28441 gcagattcaa ggccgtatcc gcatttagaa ctccgactag ggtaacattg ggaaaatcca
    28501 aaccctttgc aatcatctga gtaccaagta aaatatccgc ttcccctcgc ccaaactggt
    28561 caagcaaggc ttggtgactg cctttctttc gagtcgtatc cacatccatc ctcaaaatgc
    28621 gagcttgggg aaagagttct gctagctcat cataagcctt ctgagttccc gtcccatagt
    28681 aacgaatact gcggctctta cagttaggac agacctgagg aatatccttc gagaaaccac
    28741 aataatggca gttcatagtc ttggtatcca tatgcaaggt cagagaaata tcgcagttgg
    28801 gacaagtatc caccgtccca cactcccgac acatgacaaa gctagaataa ccacggcgat
    28861 tgagcatgag aaccacctgc tcttttttaa ccagacggtc ttggatagcc tctagcaaag
    28921 gaggcgtaaa gtttgacgtc tcattttgtc cgatatagtc tcgaaagtca atcacttgaa
    28981 cctcagggat tgtagccaaa ggattggcac gttgggttag acgtaagtgt tgatagacgc
    29041 ctttgccagc acgtgcccgg ctctctaagc tcggcgttgc agatccaagt accagagttg
    29101 cttgattata ctgagcccgt aaaatagcta cctctctggc atggtaacgg ggattgctgt
    29161 cctgcttata agccgcttca tgctcttcat caataatcat gacacccaga tttttcagag
    29221 gagcaaagat agcagatctg gcaccaacaa caacttgggc atcgccacgc tccaccttgc
    29281 gccattcatc atacttttca ccattggata atcctgagtg aagaatggct accttgtccc
    29341 caaaacgtgc tataaaacgc tcggtcatct gaggagtcaa ggaaatctca ggtaccagca
    29401 aaatagctgt cttgccctta tccagggcac cttggataat ctgcaagtaa acctcggtct
    29461 tcccacttcc tgtaatccct tgaagtagaa agggaggttg agaactgcca atagaactca
    29521 caaccgcatc acgcgcctgt ctttgttctg gatttaactc caaaggtcta cttgcttcaa
    29581 ttccttcaaa ataagcagcc gagcgttgaa cttccttttg gactatggta acagcacctt
    29641 gatccacaaa gaagttgact tgctctcgcg agtaggactc taacaagcta gccaaggaag
    29701 cgctctctgg atgagacagc agataatctc tcagttccaa ctttttcttg gcacgtgtag
    29761 aaatctcaac accttctaat tgagcatggt caacctcata ccaagactgg gtcttgacct
    29821 tcttttgatc gactgcctga tattccagac caagcaggcc ttttctagtc aaacgcatca
    29881 tttcagcttg cttggcaagg tctagtgaag aaaaggctag cgaatcttct gaaccaaaca
    29941 ggcgcactag ttcttcctga ctcaagcctt ccagaggata gagaatcttg tcatagctag
    30001 aattcagaaa tcctggaagc atagccttga ggatagaaat tttgtaggag aagacagatt
    30061 tgcgtaactc ctcagccagc cagagttgtt ctggcgtgag aacaggagaa aaatccagca
    30121 cctctgcaat atcttttaaa tcttgctcca tctcttctcc atctgattgg gactccaaac
    30181 caagaacaat cccttgaatc aggcgattcc ccttaccaaa aggcacatga acccgcatcc
    30241 caacttccag cattccctca aattcctccg gaatcctgta actatagggc tggtccgtct
    30301 gcatcaaggg cacatctacg ataatcttag ctagggccat cgtctcacct cctccttgtc
    30361 agtacattct tgcaatagaa aaaataagat tgagtccccc caaccttaaa ttttttcacc
    30421 atcttctttt tctttagcaa tttgctcttt gattttcttt tcttcttctt ctttgcggcg
    30481 tttttcttct tcgatacggc gacgcactgc ttcacgtttt ccttctggat ctgggtgaat
    30541 tgtaacgttt cctgattcga tttcttctaa agcgcgaaga gttgattttt cagacttaaa
    30601 accttgagtt gctggggcac ctgcttccaa ttcgtgggca cgttttgctt ccaagattac
    30661 gagtgaatat tttgaaggaa ccttgtcgag caaggtatca atagagggtt ttaacatcat
    30721 ttgcttgtac ctattttcta aattttatcg ggtagttgga gattttggta acatctcctg
    30781 atagtgacca atgacacgat ccacacagaa gtgttctgct tcaatcacac atttgacacg
    30841 ttcagcagct aggggcacct gatcgttgac aatcgcataa tcatactcac gcatgagggc
    30901 aatttcttcc ttggcctttt cgattcgttg ggcaatcact tctgcactat ctgttccacg
    30961 acctaccaag cgatcttgca attcatccaa atctggtggt gtcaggaaga taaagacagc
    31021 atctggaacc tttttcttga cctgaagagc accctgaact tcaatttcaa ggaaaacatc
    31081 gattcccttg tccaaggttt cattgacata ggtcagagga gttccatagt agttgccgac
    31141 atattctgcg tattccaaca tctgtccttg acgaatcagc tcttcaaatt cttcacgagt
    31201 acggaagaaa tagtcaacac cgtccacttc tccaggacgt tgtgcgcgtg tcgtcatcga
    31261 tacagaatat tgaaattggt tttcagaact ctcaaaaatc tctcttctaa ccgttccttt
    31321 tccaacccct gaaggaccag aaaaaacgat tagtaagcct cggtctgcca ttgtgtctcc
    31381 ttttagtcaa tctgtgaaat aacatttctc tagaataatg gcaaaaagcc agattatcct
    31441 ttacagtctt tctatctagt gtaacaaaaa agcagtaatt tttcaactgc tctttcttat
    31501 ttatttagca taatctactg cacgaagctc gcgaatcacg gttaccttga tatttcctgg
    31561 ataatcgaga ttgttttcaa ttttcttacg aactttgtga gccaagattg tgactttgtc
    31621 gtccttgatt tttcctggat tgaccatgat acgaatttca cgtcctgctt gaagggcaaa
    31681 gctagtttgc actccttcaa agccgttagc aatttcttcc aaatcatgga gacgcttgat
    31741 gtagctttca agagactcac tacgagcacc tggacgggct gcgctcaagg catctgctgc
    31801 agcgacgata actgctatca cgctctcagc ttcaacatct ccgtggtgac tagcaatcgt
    31861 attcaccaca actgggggtt ccttgtactt acgggccaat tccataccga tttcaacgtg
    31921 gctaccttca acctcatggt caatggcttt cccgatatcg tgaaggaatc cagcacgacg
    31981 ggcaagagcc gcattttcac caagttcgct cgccatgata ccagccaact tagcaacctc
    32041 aatcgaatgg cgcaaaacat tttgtccata tgaagtacgg aactgcaaac gtcccataat
    32101 cttcatcaag tctggatgaa ggtttggcgc accaatttca taggcagcag cctcaccgta
    32161 ttcacgaatc ttattgtcaa tctcttgacg gtttttctca accaactctt cgatacgagc
    32221 tggatgtata cgaccatctt tgagcaacat ttccatagtc atacgggcaa tctcacgacg
    32281 aatcggatca aatcctgaca aggtcaccac ttctggtgta tcgtcgataa tcacatcgac
    32341 ccctgtcaaa ctttcaaagg tacgaatgtt acgaccttca cgaccaataa tgcgtccctt
    32401 catagtatcg tctggcagat gaactgttga gtttgttgac tccgctacat attcaccagc
    32461 gatacgttgc atagcttgaa ccaagatgtc cttggccatt ttgtcagaac gttccttgac
    32521 ctcttgctca gcttcgcgaa tgcgactggc aatctccctg gtcaagtttt cctctgtctg
    32581 agccaagata atatctcgtg cttctgcctg agacagagca ccaatacgct ctagttctgc
    32641 ttctttttgt ctttcgactt cctctaattg ctcttcacgc gcatcaaggt ttttcgctct
    32701 atcagaaata ctttgttctt tttgttcaag tgtttgttct ttactcgtca aattgtcgtc
    32761 cttacggtca aggctagtag ctctctctgt caaacgactt tcgatttgtt tgagttcttg
    32821 acgttctgat ttgaattcag cgtccacttc ttcacggtat tttctggctt cttctttggc
    32881 ctccaatagt gcttcttttt taagagactt gctttcacgt ttggcttcat taacaagtaa
    32941 atccgcttca cgctcagctt gtccacgtaa attagttgct tcttgttcag catttaaaag
    33001 catcaactct gcagcttcct gagatgattt catcttagct gagatgctga catatccaat
    33061 gactaaacca atgatgacgg caaaaacagc aatcgcaagc gacatgattt ccatgttttt
    33121 acctcatttt attgttattc cgaatgacat acattctttt acattctacc ataaaaaagt
    33181 gattttcaca aacctaaaat agaatatgtt ttggggaatt tggaacacat ttgcaaaaat
    33241 aaacttgttg tttagaaata gtagtttagt agagacttga gaaaaagcct actttacagt
    33301 agacttccta atgattatgc aatacaagaa gtttgtttct aacaacagca agatttcact
    33361 caggtattct ctgtaaatga gactagtgtc ctgcgcgaat tttatccatt cctcgcaaaa
    33421 ccttgtctga taactcctta ttttgggcga ttctcagggt ttcctgaata ctgtcccatt
    33481 cgctctttga aagaactaca atgtcctcat ctggattttt attgaccacc gtcaaaggct
    33541 caaattcatc atttaccttc ttcatgtagt cctttaaatg atttcggaat gttgagtaaa
    33601 ggactgcttc cataaccata cctcgtttta gctcttttcc actattatac acaaaaagaa
    33661 agaaattgtc aggaacttgt acaagatttt cttttctatc tatttatact caatgaaaat
    33721 caaagagcaa actaggaaac tagccgcagg ctgtacttga gtacggcaag gcgacgttga
    33781 cgcgatttga atttgatttt cgaagagtat tattcgtaaa aaatctcaaa aagcctacct
    33841 tttagtagac ttagtttgtt tctattctaa tcggcactct tccaaaattt tgctctgcta
    33901 tacttggatt tcctagttgg taaatctggt ctgctttttg ggtcatagca tcccaaggtt
    33961 ctttgccaat tcggctgact agactgacct gacctttcaa agacttgaga tgttgcctac
    34021 ctttttcagt aaatccaagg acatgaatga cttctggcaa gacattttct ctagcctgca
    34081 tcaaaatata ggtcaatagg cgtctgacac gcgccttggt gtaacgtttg gtagtcacta
    34141 actcgaccaa ttcttccaca gactgggctg ttttaatagc ttctttaatg cgcacagcca
    34201 tttcttgatt gacctgatag atggtggtta ggtcgggatt tgacaagatt tgatagcgga
    34261 gcaagggaaa atagtcttcc cagatcacct tactggcctg ctcaaatagg gcaacagaag
    34321 gcataaaacg ttctaagaaa tcttggtcct tctgatgttg acggagggct gtcgccgagg
    34381 caaagtccac atctttattc acagaatggt aacctgcccc ctgacgctga atcggatgca
    34441 gcttgatatt tcgtcctgca accgcctttg cataggccag agcaagaaca tgattggggg
    34501 tattacctga aaaatcaaga ccagcaaatt ccttccacat agattgggtt ttctggggat
    34561 aggaaaggga atcaggcaga ttttccacaa atttctccat ctcagcacct ttctctgtgt
    34621 ataagtcagc gattttctga taatctcgaa cttcctctgt cccaaaaact agactatcaa
    34681 tgcccaagcg atccaagata tccacagctc cttgaccaaa gaaatcagct gcctgaacac
    34741 tgactaaaaa gggcaattcc actaccaagt ctgcgccatt ttccagcgcc atctgggccc
    34801 ttgtccactt atccacaata gcaggctctc cacgctgcat gaaattccct gacatggcaa
    34861 caattttcag tccctctgcc tgatccagca ggtatttatg gccattatga aaaggattga
    34921 actccgcgat aatacctgtg atggtcatgc taatctccta cttctgcgcc acaaaaaacc
    34981 aacgggtgct agtttctgtt ggttccttat cctcaaagtc tgcatagagt ttgaaggact
    35041 tgaatccagc ctgttccagt aagatatcat aggtcaagat ctcataggtc ctctcctcat
    35101 gtacttcatc gtggcgacta aaggaaccgt cagcctcctt gataaagaaa gtcagctcat
    35161 gcacgatgga gtgaggagct tcgtcctcat atgtatccca aagcatggca aaatcttccg
    35221 cattttcatg gtaggaatag ccagggaata cttcatctgt ctggtaggtc gagtgcacgt
    35281 caaagatgaa aactccctct tcattcagcg cattgtacac gtccttaaag acgtccccta
    35341 cttccacctc atcctgcata tagcagatag agtccgaata acacgtgaca aaatcgtatt
    35401 tccctgcctt ggacaaattc agcatattac cttctataaa agcaatcttt tgcttggctg
    35461 aagttgctct cttctccgca atcttcaaca tatccgcact caagtcaagt ccagtcacat
    35521 caaaaccagc ctgagagaag cgcactgatt gaattcctgt cccacaagcc aattccaaga
    35581 gtttctttct ctccttggtc ttaggcaaat gacgcagaga aaaattcgtc catttgtcgt
    35641 ataaactatc gtccatgacc gcatcataga ccgccgcaaa ggtttcataa gtcgccataa
    35701 tcatgatacc aagagctcca tggtaaacac cactagccct ttacctttct atcaattttt
    35761 ctaaaataag caaagaaacc cagttgatta caactgagtt catcttctaa gcaagagctt
    35821 ctgaaatatc tactgaattc gcctcatgcc ataacttctc tagattataa tgggcacgca
    35881 tttcttctga aaagatatgc acgacaacag caccgaggtc cagtaagacc cagcctccag
    35941 ctgcatcgcc ttcgacatgg ctacctttaa agcctgcttg agctactttt tcacggatat
    36001 tagctgcgat agcgtccaac tgacggctat tcattgagct agtgatgaca aagtagtccg
    36061 tcacactagt caaatcttgt acatcaagtg cgaggatatc ctccgcacgt ttctcatcag
    36121 ccgctttcac gactagttct agtaattctt tttcgttcat ttaatcctct ttttagaaaa
    36181 tatgtttgta atctaggaca tctgcaaagc gctcctccca aatgtcctca taaaattcat
    36241 taatcgtttc tgctggaatg tcatccccat caaaggttgt gacagcacct tctggaacaa
    36301 taagctgata gccatattca aaggcaacct tgacagaggt atccacacaa tattctgtct
    36361 gcataccaca taaaactaat ttttcaatcc cctgcttatc caagtattct tttaagccag
    36421 tttctttgaa aatactgtta tatttcttct gaaagacctt ttcagcaggt tttcgattta
    36481 aaagcgcaga taactgccaa tcttctgatg tttgagcttc agagttctca atatgttgaa
    36541 catagataat ttcaatattc ttgcttctag cctggttttg taaataagaa attttttcca
    36601 atagactttt tgtctggaac ccagtttcta ctaaaacatt ctgaacatca atgattataa
    36661 aagccatctt catttagttc tctttcaaat agtgcacaaa ggcgttatag gtttcaaggg
    36721 tttggggata gatggggaat ccctgatgag ctagatactc cacggtacga gctgtttcgt
    36781 aggccaccgc cttattgagc gatagacttg caatctcacg cgccacatct actccaggaa
    36841 aggctcgatt gtgctcgata tagtctgcta cataaacaac cttatctagg tctgtcatct
    36901 gaccagcacc gactgtatgg acttcaatgg ctcgcaggat ttctgaatca tgcaaatcca
    36961 aatcttcctg aattttgtaa attccgacca taccatgcca gacattattg ccccagtttt
    37021 tgaggtcagg gtctagctgg taacggtcaa tcaaggctag aaattcctga tttgacaact
    37081 ttttagcata gtcatgaaga agacctgcta gacttgcttt ctcaacatct acaccaaagc
    37141 gctgagctaa ttccatagcg gcacgctcca cacccaagca atgggttaag cgtttttcag
    37201 gtagaaactc taccattttt tccaacaagg cctcacggga gcagttgata tagtcttgat
    37261 aggacatcag tagagcccct ccttctcgat gtagtctagc actggctgag gtaggagaaa
    37321 gttgggtttc cgaccttggg caaggaagtc ccgcaccatg ctggacgaga tatccatgag
    37381 cggtacgtcc acccagataa ctggatagga agtccctacc ttgtagcgtg gacgctgaac
    37441 ccccacaaac tgaaccatgt caaccagttc atcaattcgg taccacttag gcagatagtc
    37501 aaccatgtcg gcaccgatga taaagtaata atccgtatct ggattcttct ctgtcaaaat
    37561 cttcatggtg tcgtaggtgt aggaaatacc cttgcgctcc aactcaatgg tttcaatgac
    37621 taggccgtca attccctcaa ttgccaactc aagcatcttg agacgatggt gttcagggat
    37681 ggtttccttt ttatcaacgt gaggaggttg gtattcaggc atgagaagaa cttgatccag
    37741 tcccaactgt tgccgtactt gatccgcaac aatgagatgg gcattgtgaa cagggttaaa
    37801 attcccccct aaaatcccaa cttgtttgcg ttttttctcc ttgatttctg gctccaactc
    37861 taccttggta aagggagtca atagttcgat tgtcataggc tagtcccctt tatttctcta
    37921 taaaaacagt tatttggagt ttcggtctta gatttctttg actttcttag aaatcttgcg
    37981 attttctttc ttgctagatt gtttaaacaa aatcaagatg cgtcctattt tttggactgt
    38041 atccacaccg atttcttctt ccaaaatttc agctacttcg tggatgtttt catctgtgtt
    38101 ttgtaagaga gtaaccttga ttaattcacg cgcatcaaga gcttgacgga cgctggtttt
    38161 gatttggtcg ttgagtccat ttttcccgat ttggatgata ggtttgaggg tgtgtgcctg
    38221 gctgttgagg aaggcacgtt gttttgatgt taatgacata aatttcttcc ttgtttttgg
    38281 atagttattt taggtggtga gggacggtcg gaactaattt tccaaagatt tcatctttga
    38341 aaaatggatt tcctgacctc acaattgagc cttggtctca attgtgcccc ttgccaatct
    38401 acagattggc aatcacacca cggcaataac tatcgctata tgagctcact ttgttcgctc
    38461 agcgattttg ttttaaataa ttgcttttcg tgtgacgacg gcgacgcctt ctggtgccca
    38521 gacggcgact tttgctgtgc ctgttacacg aatccatcct aggcctgaga tgactaggtc
    38581 tgtcttatct ttaatggtaa agacatgctg gactagcctt gggaaatctt ctttttcctt
    38641 gctatttggt ggtgtcagaa gagttcccag gtgcttatcg tagaaagcac tagctccttc
    38701 aagcttgcta cgatggagtt tgagttcatt atcaaagaaa gcagtaaatc cttgcttttc
    38761 tcctgctata aagtcaaagc gtcccaaacc acctaaaaat agggtttgct caggattaag
    38821 ctgataggtc ttaggcttga tttccttttt aggactgaca tacttgaggt ttttggccgt
    38881 caagtagtga gccatctggt ggcggtggat aattcccggc gtatcgtaaa tataagatcc
    38941 gtcgtcaagc ggaatctcta ttttgtccaa ggttgtccct gggaagcgtg aagtagtgat
    39001 gacattctga tcacccgtga tttcttggat aatagcattg attagagttg attttccaac
    39061 gttggtcaca ccgaccacat agacatcgcg gcccttacgg tagtgttcaa tcttatcaat
    39121 gacttcctta atggcatgtt tattttgtgc tgaagttagg accacatcga ctggacgaag
    39181 accttcttca cgggcacgtt tcatgagcca ctggctaatc ttaccagact taactgactt
    39241 aggaaggata tcttttttat ttcctaccaa gaggacatca ttgcccgaga cgaaacgtgg
    39301 taaacctggg atgacagatc cattaaaatc aaagatatca atgacattga ccactaaggc
    39361 attactgtct cccacctcgt gcaagagctt gaggaaatca tcgttcgtca actggacatc
    39421 tgtgatttca ttgtagtggc ggagacggaa acagcgttgg caatagactt cgccagtctc
    39481 caaacctttt tcaagtgccg actggggggt aaaaccaaga ccagctttat ctgtcgtctg
    39541 aatggttgct ccacaaccaa tacagagaat ttcttccata gttaaattcc ttttttatat
    39601 gtaatcggtc cgtacttttc agtgattttt ctcataacac gacgctcacg agttcggtta
    39661 atctgcgttt tgattgagtc atgttggacc aagggtttga ctaaaattga ccgaatccct
    39721 gcacggtggg ctgctcgtat atctgtcatg agctggtcgc caaccatgac cacttccttt
    39781 ttgtcatagt ggaattcctt catagcacgg tcaataccaa atgtgaaggg cttcaaggcc
    39841 cagtaaacgt aatcaatccc aaatttctca actgctcgtt gaacgcgttt tttggtgtta
    39901 tttgacacta cgataatgcc aatacccgcg tcccgaaggt catgtagcca ttgcttcatc
    39961 tctggcgttc catcagggtt gttccaagca atgagggtat tatccaaatc gaccaaaaca
    40021 gccttgattc cctgcgcctg caggcttggg actgtcagat catagactgc ttccacagca
    40081 aaatctggta tataattttc aatcgccatt ctggctcctt ttcttaactt tttttcgcaa
    40141 ttttccttag taacaaggat aaaacaatcc acaaacctgc actagccaaa ctgatataga
    40201 gccaagcatg gggctcatct gttaaaggta agggaacatt cattccgaaa aagcctgtca
    40261 cgactgccaa aacagctagc aagactgaaa tgatagtcaa ggttgtcaaa ttgtcattca
    40321 gattattgtt tagaatattg ttgtaagagg ctgaaagctg ctgtaaaatc tgagagatta
    40381 ggtctgtcat ggataccagc tgatgagcct caatcatggc atcatcaaac tgttctctct
    40441 caatctcatc aaaactacga tacaaggcat gaccttgaat atgctctaac aaaatccgat
    40501 tttgtttggc agctgccgtc agataaacca taccagtctc caaatcagac aggacaaaga
    40561 ggtttttctt ggtagttcgc tggcgcaaga ggtcattgac ctcatcccta ctcttgtcca
    40621 tctgctcaat gacaggatag taggcattgc tgataatttc cagactggca aagagaaact
    40681 tataaatcga aagcgtgtca tggttctcca gataacgagt catctgttca atgacatagg
    40741 cgttcttggt attactaatg gtaatcaggc gacgatgctc gacaataaag gtcatgggaa
    40801 aagtctcata gtaggccttg tcctttttta cgtctaagac attatagata aaggtaaccg
    40861 tctcactttc acggtggtag tccatgtggg cgcgctcgtt tctatccagt gcgtattcaa
    40921 tggtttcctt gtccaaaccg taaatttcag aaaggtcttc tagtttattc aactttccta
    40981 ggtctaggtc tatccaggta caaccattgc ccaactgctt ttctaaaacc atcttttctc
    41041 cttattaaac tccctctatt gtaccacaaa ttacttaaaa taacaggtct agtctgtgcg
    41101 tgagaaattg ctaacaactg tgatatttcg gttagggaca aagtgaaggg cttgctcctc
    41161 gctacgaagc tgtgtcgtac gaattcccac actgacaacc ttacccgata cagtaatcgg
    41221 tccatttgtc agaacgacct catctcccac atccagttga cgttcaaaga ggatgaaaaa
    41281 gccattgatg acatcagaca gaaagccttg ggctcccata ccaatcgcta ccccagcaat
    41341 accagctcca gccagcaaac tagaaactgg caaacctaaa atcgacaaaa tgcagtagag
    41401 taaaaagaaa tatagcgtat aattaaacac attttctagt aaacgtgaga tggttttttg
    41461 gcgtccaaca tcatgacgag acatttttag agaaggtttg acaattctct gcaccatggt
    41521 atgaagcatt tttttagcaa tataaaatac aatcaaaagc agtaaaagag aaatgacctt
    41581 ggttagaata ttctcgataa tggttgtcac atctagcttt tcaatataag cctgaataaa
    41641 tttttgcata taaaactcct ttatttcatt ataccatatt ttcatcagtc tcattctcca
    41701 taaatattca aaaaatagac agaaaattct tgattttgtc tatcatttat actataatca
    41761 taatcactac acaaaaagga gattattatg aaaagaatca ttcatgcttg gaataaggca
    41821 agccttgtca agcgtatctt gattggtatg ctttgtgggg aatcctagga ctgacccttc
    41881 ctaatctctc agggattggg ctactcgggg atttattcgt tggaggtcta aaagctgttg
    41941 ctcctatcct agtctttgcc ctcgttgcca atgccctttc ccaacatcaa aagggacaag
    42001 atagcaatat gaaaactgtt gttttcttgt atatcctatg atagggactt tcgccgctgc
    42061 tcttgtagct gtactagcaa gtttcatcgt ccctattgaa attaccctaa atagtgccaa
    42121 tactgaaatt gcaccaccag atgggattgg gcaggtcctc agcaacctct tgctcaaact
    42181 ggttgacagc ccagtcaacg ccctgcttac tgctaactat attggaatct tatcttgggc
    42241 agtcattttt ggaatcgcta tgagagaagc cagtaaaacc agtaaaaata gtaaagaatt
    42301 gctaaaaact atcgctgacg tgacttctaa aattgtcgaa tggatcatca atctggctcc
    42361 atttggaatc cttggtcttg tttttaaaac catttctgac aagggagtcg gaagccttgc
    42421 caactacggt attttattgg ttccattagt aacgactatg ctttttgttg cccctgtggt
    42481 caaccctttg attgccttct tctttatgag acgcaatcct tactctctag tttggaactg
    42541 cctccgtgtc agcggtgtga cagccttttt cactcgtagt tctgcgacta acattcctgt
    42601 caacatgaaa ctctgccatg accttggact caacccagat acctattctg tttctatccc
    42661 actcggttct actatcaata tggctggagt agcgattacc attaacgttt tgacccttgt
    42721 tacagttaac actcttggaa ttcctgttga ctttgccaca gcctttgtcc tcagtgtggt
    42781 agcagctatc tcagcctgtg gtgcttcagg tattgccgga ggttccctcc ttcttatccc
    42841 agttgcttgt agccttttcg gtatttctaa cgatattgcc atacaagttg ttggggttgg
    42901 ttttgtgatt ggtgtcatct aagaatcatg tgaaacagcc cttaactctt ctacagatgt
    42961 cctctttacc gccgttgccg aatacgcagc aacccgtaaa aaataactca tcaaggcaag
    43021 cctgctcatg tcttgtcttt tacgctttta ttctaactta ttaggaaatt cttatgtcta
    43081 ttagccaacg tacgaccaag ctcatcttag ctacctgtct tgcctgcctg cttgcttatt
    43141 ttctcaatct ttcgtcagca gtttcggctg gaattatcgc tctcttgagc ctatctgata
    43201 cgcgtagaag tactttaaaa ctggctcgca atcgtctttt ttctatgctt ctagctctgg
    43261 ctatcggtgt tctagctttt cacttgagcg gatttcatat ctggagtctc ggcctctatc
    43321 tggccttcta cgttccttta gcctacaaga tgggctggga aattggcatc acaccaagca
    43381 ctgttttggt tagccatctc ttggttcaag agtcaacctc tccagacctt ctagtcaatg
    43441 aattccttct ctttgctatt ggtacaggat ttgccttgct tgttaatctc tatatgcctt
    43501 cacgagaaga ggaaatccag cactaccaca cgctggtgga agaaaagtta aaagatatcc
    43561 tccagcgctt caaatactat ttatccagag gagacggacg caaccgagca cagctggtag
    43621 cagaattaga cacgcttttg aaagaagccc tcagactggt ctatttggat cactctgacc
    43681 acctctttca ccagaccgac taccatatcc actactttga gatgagacaa cgacaaagtc
    43741 gtatcctgag aaacatggcc caacagatta acacttgtca ccttgccgcc agtgaaagcc
    43801 tgatcttagc gcaactcttt tcaaaaattg caggtcaact gagccagacc aatcctgctt
    43861 ctgatttgct agatgaaatt gaacgttatc tggaagtctt ccggaaccgc agtctgccca
    43921 agacaagaga agaatttgaa acccgcgcca cccttcttca actcctacgt gaagccaaaa
    43981 ccttcatcca agtaaaagtt gatttttacc aaaaatatag acagtaatac tcttcaaacc
    44041 acgtcagcgt cgccttgc
//
LOCUS       DAVLUM010000005        40298 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLUM010000005 DAVLUM010000000
VERSION     DAVLUM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.005"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            12..512
                     /locus_tag="VYN42_000217"
     CDS             12..512
                     /locus_tag="VYN42_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461361.1"
                     /translation="MKNERRERWTQLSSQRMSRVLWTIELIANLSSHNYEYKDEWLGY
                     LFDSIKQKGDEIKEVFQNPTDALSNKLISEFEFPKEMFRSQPSPKELKFKNVAERRIT
                     KLYKEMNYFSRLANTKNYTYDSIDVDFLFDCYSNKYYELVSWFPPFIKDRVCNDINVA
                     DFPSER"
     gene            540..818
                     /locus_tag="VYN42_000218"
     CDS             540..818
                     /locus_tag="VYN42_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461362.1"
                     /translation="MNYWNDIKNIITEWHSIDYRVTEREDFETVKLRAIRDFQHYLKL
                     LDENTEEGYQEVIRLFTFSKFYGEELCNDEKLNKLSRDIRGRLKQFRS"
     gene            1080..2357
                     /locus_tag="VYN42_000219"
     CDS             1080..2357
                     /locus_tag="VYN42_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1461363.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2433..3917
                     /locus_tag="VYN42_000220"
     CDS             2433..3917
                     /locus_tag="VYN42_000220"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1461364.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNALNTQGQYELTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTNDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVCHKTTVAAADMQVAVEAYLGL"
     gene            3978..5258
                     /locus_tag="VYN42_000221"
     CDS             3978..5258
                     /locus_tag="VYN42_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1461365.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            5262..5885
                     /locus_tag="VYN42_000222"
     CDS             5262..5885
                     /locus_tag="VYN42_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1461366.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFEAER"
     gene            6047..7225
                     /locus_tag="VYN42_000223"
     CDS             6047..7225
                     /locus_tag="VYN42_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1461367.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALDVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7548..7973
                     /locus_tag="VYN42_000224"
     CDS             7548..7973
                     /locus_tag="VYN42_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1461368.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7984..8343
                     /locus_tag="VYN42_000225"
     CDS             7984..8343
                     /locus_tag="VYN42_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1461369.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8450..9094
                     /gene="pcp"
                     /locus_tag="VYN42_000226"
     CDS             8450..9094
                     /gene="pcp"
                     /locus_tag="VYN42_000226"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1461370.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGEIH"
     gene            complement(9121..9978)
                     /locus_tag="VYN42_000227"
     CDS             complement(9121..9978)
                     /locus_tag="VYN42_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1461371.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10108..11250
                     /gene="tgt"
                     /locus_tag="VYN42_000228"
     CDS             10108..11250
                     /gene="tgt"
                     /locus_tag="VYN42_000228"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1461372.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11351..13168
                     /locus_tag="VYN42_000229"
     CDS             11351..13168
                     /locus_tag="VYN42_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1461373.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13321..14472
                     /gene="nagA"
                     /locus_tag="VYN42_000230"
     CDS             13321..14472
                     /gene="nagA"
                     /locus_tag="VYN42_000230"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1461374.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVGDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14635..15693
                     /locus_tag="VYN42_000231"
     CDS             14635..15693
                     /locus_tag="VYN42_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1461375.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLDTAVSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15844..16209
                     /locus_tag="VYN42_000232"
     CDS             15844..16209
                     /locus_tag="VYN42_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1461376.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16285..17226
                     /locus_tag="VYN42_000233"
     CDS             16285..17226
                     /locus_tag="VYN42_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1461377.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17174..18190
                     /locus_tag="VYN42_000234"
     CDS             17174..18190
                     /locus_tag="VYN42_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1461378.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18192..18518
                     /gene="comGC"
                     /locus_tag="VYN42_000235"
     CDS             18192..18518
                     /gene="comGC"
                     /locus_tag="VYN42_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1461379.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQVDGRITEEQAKAYKEYHDKNGGA
                     NRKVND"
     gene            18511..18915
                     /locus_tag="VYN42_000236"
     CDS             18511..18915
                     /locus_tag="VYN42_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1461380.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18920..19180
                     /locus_tag="VYN42_000237"
     CDS             18920..19180
                     /locus_tag="VYN42_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461381.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19143..19604
                     /locus_tag="VYN42_000238"
     CDS             19143..19604
                     /locus_tag="VYN42_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1461382.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            19582..19992
                     /locus_tag="VYN42_000239"
     CDS             19582..19992
                     /locus_tag="VYN42_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1461383.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKSEEKPEKKENS"
     gene            20129..20716
                     /locus_tag="VYN42_000240"
                     /pseudo
     CDS             20129..20716
                     /locus_tag="VYN42_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20777..21730
                     /locus_tag="VYN42_000241"
     CDS             20777..21730
                     /locus_tag="VYN42_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1461384.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21781..22971
                     /locus_tag="VYN42_000242"
     CDS             21781..22971
                     /locus_tag="VYN42_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1461385.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23120..23491
                     /gene="rnpA"
                     /locus_tag="VYN42_000243"
     CDS             23120..23491
                     /gene="rnpA"
                     /locus_tag="VYN42_000243"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1461386.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNRFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23466..24290
                     /locus_tag="VYN42_000244"
     CDS             23466..24290
                     /locus_tag="VYN42_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1461387.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24309..25295
                     /locus_tag="VYN42_000245"
     CDS             24309..25295
                     /locus_tag="VYN42_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1461388.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25346..25969
                     /locus_tag="VYN42_000246"
     CDS             25346..25969
                     /locus_tag="VYN42_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1461389.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKVFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26100..27557
                     /locus_tag="VYN42_000247"
     CDS             26100..27557
                     /locus_tag="VYN42_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1461390.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27580..27861
                     /locus_tag="VYN42_000248"
     CDS             27580..27861
                     /locus_tag="VYN42_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1461391.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27938..28423
                     /locus_tag="VYN42_000249"
     CDS             27938..28423
                     /locus_tag="VYN42_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1461392.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28440..29105
                     /locus_tag="VYN42_000250"
     CDS             28440..29105
                     /locus_tag="VYN42_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1461393.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCTTIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29109..29972
                     /locus_tag="VYN42_000251"
     CDS             29109..29972
                     /locus_tag="VYN42_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1461394.1"
                     /translation="MVRPIGIYEKATPTHCTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29974..30678
                     /locus_tag="VYN42_000252"
     CDS             29974..30678
                     /locus_tag="VYN42_000252"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1461395.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30857..32530
                     /locus_tag="VYN42_000253"
     CDS             30857..32530
                     /locus_tag="VYN42_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1461396.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYNLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32642..33733
                     /gene="ulaG"
                     /locus_tag="VYN42_000254"
     CDS             32642..33733
                     /gene="ulaG"
                     /locus_tag="VYN42_000254"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1461397.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33847..35823
                     /gene="tkt"
                     /locus_tag="VYN42_000255"
     CDS             33847..35823
                     /gene="tkt"
                     /locus_tag="VYN42_000255"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1461398.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35940..36239
                     /gene="yajC"
                     /locus_tag="VYN42_000256"
     CDS             35940..36239
                     /gene="yajC"
                     /locus_tag="VYN42_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1461399.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36285..36713
                     /locus_tag="VYN42_000257"
     CDS             36285..36713
                     /locus_tag="VYN42_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1461400.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36715..37125
                     /locus_tag="VYN42_000258"
     CDS             36715..37125
                     /locus_tag="VYN42_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461401.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37425..40076
                     /gene="adhE"
                     /locus_tag="VYN42_000259"
                     /gene_synonym="adhC"
     CDS             37425..40076
                     /gene="adhE"
                     /locus_tag="VYN42_000259"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1461402.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12403 a         7130 c         9001 g        11764 t
ORIGIN      
        1 aggagaagac aatgaaaaat gaacgcagag agcgatggac acagcttagc tcacaaagaa
       61 tgtcacgagt attatggaca atagaattaa ttgcaaatct atctagtcac aactatgaat
      121 ataaagatga atggcttgga tatttatttg attcaatcaa gcagaaagga gatgagataa
      181 aagaagtatt tcaaaatcct accgatgcat tatctaataa attgatttca gaatttgaat
      241 ttccaaaaga aatgtttcgt tctcaaccta gcccaaaaga attaaaattt aaaaatgttg
      301 cagaaagaag aattactaag ctatataaag aaatgaacta ttttagccga ttggctaata
      361 ccaaaaatta tacatacgac tctattgatg ttgactttct atttgattgt tactcaaata
      421 aatactacga attggtgagc tggtttcctc catttataaa agacagagtt tgcaatgata
      481 ttaacgtagc tgattttcca agtgaaagat agttaaattc tatgatttgg agaaggaaaa
      541 tgaactattg gaatgatatt aaaaatataa taacagaatg gcactctatt gattacagag
      601 ttacggaacg agaagatttt gaaacagtaa aactaagagc aattagagat tttcaacatt
      661 atctaaaatt acttgatgaa aacactgaag aaggatacca agaagttata agattattta
      721 cattcagcaa attctatggt gaagaactgt gtaatgatga aaaactgaac aaattgagta
      781 gagatataag agggagatta aaacaattcc gttcctaaaa tgttactaaa aataaaaaaa
      841 ctatcgtttt tgtgatagag gtaacttttt gaaaaggcta tttgactggc tttatatact
      901 tatgaaacgt taagagtcca actcaaaatc cagtgtccgc aaggacgtgc cggttcgacc
      961 ccggccgccg gtatagtata gtgttaggaa cgttgttatt cttcgttcct tttttatatt
     1021 atttttggta taattatagt tattcaaatt ttgtttagat tgagaaagtg tagggtagta
     1081 tgtcttgttc tatcgattta ttaaaacatc ggtatttgaa aaatattaaa gaaaatcctg
     1141 aattgtttgt cggaattgag ttggagtatc ctgttgcaag tttagaaggg gatgctacag
     1201 atgttgaagt tataaaggat ctatttcatt atttagtttc tactttggat ctcaccgtag
     1261 caaaggtaga tgattttggc aatctgatcc agttagtaga tccgataagt caggatgcta
     1321 ttttatttga agtttcctat acaacgattg agtttgcatt tggtaaggct gaaacgattc
     1381 aagaggtcga aaatcgtttc aataattata tgaatgtaat tcagagaaag ttagctgaat
     1441 caaatcatgc tattgttggc tgtggtatcc atcccaactg ggataaaaat gagaattgtc
     1501 cagtggctta tccacgctat cagatgttga tggattattt gaatttgagt agaaatatta
     1561 ttaaatcaga tttacatcat ttccctgaat atggtacttt tatctgtggg agccaggttc
     1621 agctggatat ttcaaaaacc aactacttac gggtgattaa tgcttttact caaattgaag
     1681 cggctaaggc ttatttattt gcaaactctg aattttcggg tgcggattgg gatacgaaaa
     1741 tttcaaggga tattttctgg gaagaatcta tgcatggtat ctatccagag aatgttgggg
     1801 tcaatgctag actccttaat gatgaagctg atttttttga ctatctaaat cattctgcga
     1861 tttttactgc ggaacgtgat gggcagacct attattttta tcctattcag gctggggact
     1921 atttggctac gcctgaaatc caagcatttg ctctgaatgg ggatgaggtt attatttacc
     1981 cccaagagaa ggattttgaa actcatcgta gttaccagta ccaagactta acgactcgag
     2041 gaacagttga gtttcgtagt gtgtgtacac agccacttga taggactttt gcttctgcag
     2101 cttttcactt gggattattg gttaatttag acaagttaga agcttactta gaaacagcac
     2161 ctttctttaa agtatttggt tatgattaca agtctttaag gagacaattt tctaagaaaa
     2221 atcttacaga tgaggaagaa actacgatta ttgaattttc caaagactta ctcctactag
     2281 ctgaggaggg actagtggtg agaaataagg aagaaatgac ctatttacag cctttgagag
     2341 aagaattgag cctataattt ctcttataaa gggagaattt tctgaaaaat catgatataa
     2401 tggacgagac tatagataaa ggatagagag taatgacatt agtttatcaa tcaacgcgtg
     2461 atgccaacaa tacagtaact gccagccaag caattttgca aggtttggcg acggacggcg
     2521 gtttgtttac accggttact tatccaaagg tagatttgga ctttgacaaa ttgaaagatg
     2581 cttcttacca ggaagttgct aagctagttt tgtcagcatt tttagatgac tttacagctg
     2641 aggagttgga ctactgtatc aacaatgcct acgatagcaa atttgatact ccagctattg
     2701 caccattagt gaaattagat gggcaataca atttggaact tttccatggt tcaacgattg
     2761 cctttaagga tatggccttg tctattttgc catactttat gacgactgct gctaagaaac
     2821 atggtttgga gaacaagatt gttatcttga cagcgacatc tggtgacacg gggaaagctg
     2881 ctatggcggg gtttgcggat gtgcctggta ctgagattat cgtcttttat ccaaagggtg
     2941 gtgtcagcaa ggtacaagag ttgcaaatga ccactcagaa tggtgacaat actcatgtta
     3001 tcgctataga tggtaacttt gacgatgcgc aaaccaacgt gaagcacatg tttaacgacg
     3061 tggctcttcg tgaaagatta gcggccaaca agttgcaatt ttcatctgct aactctatga
     3121 atatcggtcg tttggtgcca cagattgttt attatgttta tgcctatgct cagttggtca
     3181 agactggtga gatcgtggct ggtgataaga ttaacttcac agtaccaaca ggaaactttg
     3241 gaaatatctt ggctgccttt tatgccaaac aaatcggtct cccagttggt aaattgatct
     3301 gtgcttcaaa tgacaacaat gttttgacag acttcttcaa gacacgtgtt tacgacaaga
     3361 aacgtgagtt taaggtaaca accagcccat ctatggatat cttggtatct tcaaacttgg
     3421 agcgtttgat tttccatctt ttggggaatg atgcggttaa gacggctgaa ctcatgaatg
     3481 ccttgaatac acaaggacaa tatgaactga ctgattttga tgcagagatt ctggagctct
     3541 ttgcagctga atatgcgact gaggaagaaa cagcggcaga aatcaagcgt gtttatgagt
     3601 tagattctta tattgaggat ccacatacgg cggttgcctc agcagtttat agaaaatacc
     3661 aagcggttac taatgatgcg actaagacag tgattgcttc aacagctagt ccctacaagt
     3721 tcccagtagt tgcagtagaa gctgtaactg gaaaagcagg tttaacagac tttgaagctt
     3781 tggctcaatt acatgaaatc tcaggcgttg cagtgccacc agcagttgat gggcttgaga
     3841 cagctcctgt ttgtcacaag acaacagtgg cagctgctga catgcaagta gcggttgagg
     3901 cttatttagg actttaagat agagggagta aactcggttg ggaaaccaac tgagtttctt
     3961 ttcatcagga ggagagattg tttaagaaaa ataaagacat tcttaatatt gcattgccag
     4021 ctatgggtga aaactttttg cagatgctaa tgggaatggt ggacagttat ttggttgctc
     4081 atttaggatt gatagctatt tcaggggttt cggtagctgg taatattatc accatttatc
     4141 aggcgatttt catcgctctg ggagctgcta tttccagtgt tatttcaaaa agcatagggc
     4201 agaaagacca gtcgaagttg gcctatcatg tgactgaggc gttgaagatt accttactat
     4261 taagtttcct tttaggattt ttgtccatct tcgctgggaa agagatgata ggacttttgg
     4321 ggacggagag ggatgtagct gagagtggtg gactgtatct atctttggta ggcggatcga
     4381 ttgttctctt aggtttaatg actagtctgg gagccttgat tcgtgcaacg cataatccac
     4441 gtctgcctct ctatgttagt tttttatcca atgccttgaa tattcttttt tcaagtctag
     4501 ctatttttgt tctggatatg gggatagctg gtgttgcttg ggggacaatt gtgtctcgtt
     4561 tggttggtct tgtgattttg tggtcacaat taaaactgcc ttatgggaag ccaacttttg
     4621 gtttagataa ggaactgttg accttggctt taccagcagc tggagagcga cttatgatga
     4681 gggctggaga tgtagtgatc attgccttgg tcgtttcttt tgggacggag gcagttgctg
     4741 ggaatgcaat cggagaagtc ttgacccagt ttaactatat gcctgccttt ggcgtcgcta
     4801 cggcaacggt catgctgttg gcccgagcag ttggagagga tgattggaaa agagttgcta
     4861 gtttgagtaa acaaaccttt tggctttctc tgttcctcat gttgcccctg tcctttagta
     4921 tatatgtctt gggtgtacca ttaactcatc tctatacgac tgattctcta gcggtggagg
     4981 ctagtgttct agtgacactg ttttcactac ttgggacccc tatgacgaca ggaacagtca
     5041 tctatacggc agtctggcag ggattaggaa atgcacgcct ccctttttat gcgacaagta
     5101 taggcatgtg gtgtatccgc attggaacag gatatctgat ggggattgtg cttggttggg
     5161 gcttacctgg tatttgggca gggtctctct tggataatgg ttttcgctgg ttatttctac
     5221 gctatcgtta ccagcgctat atgatcttga aaggatagga aatgcaaaaa acagctttta
     5281 tttgggattt agacgggact ttattggact cttacgaagc gattttatca gggattgagg
     5341 agacttttgc tcagttttct attccttatg ataaggagaa ggtgagagag tttatcttca
     5401 agtattcggt gcaagatttg cttgtgcggg tggcagaaga tagaaatctg gatgttgagg
     5461 tgctaaatca ggtgcgtgcc cagagtctgg ctgagaagaa tgctcaggta gttttgatgc
     5521 caggtgcgcg tgaggtgcta gcttgggcag acgaatcagg aattcagcag tttatatata
     5581 ctcataaggg gaacaacgct tttaccattc tcaaggactt gggggtggaa tcctatttta
     5641 cagagatttt aaccagtcag agtggctttg tgcggaagcc aagtccagaa gcggctacct
     5701 atctgctaga taagtatcag ttgaattctg ataatactta ttatataggg gatcggactc
     5761 tggatgtgga atttgcccag aatagtggga ttcaaagtat caacttttta gagtctactt
     5821 atgaagggaa tcacaggatt caagcgttag cagatatttc ccgtattttt gaggctgaac
     5881 gataaaaaga ttgtgtcagt tttgtgacag agacctaaca aactatttca agtaacctag
     5941 tttgttacaa ggaatagaca gttctgttaa ataggcccga gagggctttt tttctacatt
     6001 ttttgtgtta tcatagacag gtactcattt gaaaggattt gaaagaatga agaaaagaat
     6061 gttattagcg tcaacagtag ccttgtcatt tgccccagta ttggcaactc aagcagaaga
     6121 agttctttgg actgcacgta gtgttgagca aatccaaaac gatttgacta aaacggacaa
     6181 caaaacaagt tataccgtac agtatggtga tactttgagc accattgcag aagccttgga
     6241 tgtagatgtc acagtgcttg cgaatctgaa caaaatcact aatatggact tgattttccc
     6301 agaaactgtt ttgacaacga ctgtcaatga agcagaagaa gtaacagaag ttgaaatcca
     6361 aacacctcaa gcagactcta gtgaagaagt gacaactgcg acagcagatt tgaccactaa
     6421 tcaagtgacc gttgatgatc aaactgttca ggttgcagac ctttctcaac caattgcaga
     6481 agctccaaaa gaagtagcat caaattcaga agttgcagag acagtgactg ctgcagaaga
     6541 agtggcacta tctacagact ctactacgcc agagggacaa ccagccgaaa caactagtcc
     6601 agttgaagaa gtagctcctc aggcaacgac tctagctgag aagcaggaaa cacaagtgag
     6661 ctctcaaacc gagtcagcag tggaagcaac tacaatgcca gtagaagaaa aagcaaccga
     6721 aacaactgca acaagttcag aagcaaaaga agtagcatca tcaaatggag ctacagcagc
     6781 agtttctact tatcaaccag aagagacgaa aataatttca acaacttacg aggctccagc
     6841 tgcgcccgat tatgctggac ttgcagtagc aaaatctgaa aatgcaggtc ttcaaccaca
     6901 aacagctgcc tttaaagaag aaattgctaa cttgtttggc attacatcct ttagtggtta
     6961 tcgtccagga gacagtggag atcacggaaa aggtttggct atcgacttta tggtaccaga
     7021 acgttcagaa ttaggggata agattgcgga atatgctatt caaaatatgg ccagccgtgg
     7081 cattagttac atcatctgga aacaacgttt ctatgctcca ttcgatagca aatatgggcc
     7141 agctaacact tggaacccaa tgccagaccg tggtagtgtg acagaaaatc actatgatca
     7201 cgttcacgtt tcaatgaatg gataaacccg acttgataac atcattttga cgaatgagat
     7261 ctagctttcg tgatggaaag cgattctcgt tcgttttttc tttgtcatac tcttcgaaaa
     7321 tctcttcaaa ccacgtcagt tttatctgaa acttcaaagc tgtgctttga gcaacctgcg
     7381 actagcttcc tagtttgctt tttgattttc attgagtatc aatttgaatg gaaaatggaa
     7441 agttatcatc ttgtaatgag ttaagcaaca ttcttgcaat ctattttact ttatatcaca
     7501 attaattagt caaatattga taaatcaata aaaagagagg ggaagaaatg ctagagattc
     7561 aagatttact gtatcaactc cgcttgtctg agcaagcgag tacgcaattg tttgaaaaaa
     7621 ggcttgggat tagtttgaca cggtatcaga ttttactgtt tttgctggag cattctcctt
     7681 gtaaccaaat ggcggttcag gagcgtttga aaattgatca ggctgctttg acacggcatt
     7741 tcaaaatttt ggaaacggaa ggtttggtgg agcgtcatcg taatcctgaa aatcagcggg
     7801 aagtgttggt agaggctgcg aagtatgcca aggagcagtt agtggtgaat ccccctctgc
     7861 aacatatcag ggttaaggaa gagatagaaa gtatcttaac agagtttgag agaacagaac
     7921 tcagccgttt attaaataaa ttggttttgg gtattgaaaa tatagaaatt taaggagaaa
     7981 tagatgtcaa ttattttaac aacgatcgtt gctttggagc atttttacat tttttatttg
     8041 gaaagtattg ccacgcaatc agatgcgact agtcgtgtat ttaatatgga aaaggaagaa
     8101 ttggctcatc cgtcagtaag ttcattgttc aaaaatcaag gaatttataa ggctctgcta
     8161 ggagtctttc tcttgtatgt catttatttc tcacagaatt tagaaattgt gactattttt
     8221 gtcttatttg tgattggtgc tgcgacttac ggctctttaa cagcggataa aaaaattatt
     8281 ttgaaacaag gtggatcagc tattttggcc ttgattagta ttttactctt taaatacact
     8341 tgaaggtcga ttctaatctc gctaatcctt tttaatccag aataagggaa atatgttata
     8401 cttgttttta agaaaaaagt ctcattgaat tggttttgag gagttagaaa tgaaagtatt
     8461 agtgacaggt tttgagccct ttggagggga aaagggcaat ccagctttgg aggccattaa
     8521 aggtttacca gctgaaatcc atggtgctga ggtccgttgg ctagaggtgc cgacagtttt
     8581 tcacaaatct gctcaagtat tggaagaaga gatgaatcgt tatcaacctg actttgtcct
     8641 ttgtattggg caagctggtg gaagaactag tttgacacct gaacgagtga ccattaatca
     8701 agacgatgca tgcatttctg ataacgaaga taatcaaccg attgaccgtc ccattcgccc
     8761 agatggtgct tcggcctact ttagtagttt gccgattaaa gcgatggttc aagctataaa
     8821 aaaagagggc ttaccggcct ctgtttccaa tacggcaggg acttttgtct gcagccattt
     8881 gatgtatcag gctctctatt tggtagaaaa gaaatctcca tatgttaagg caggttttat
     8941 gcatattcct tatatgatgg aacaggtggt gaacagaccg actactccag ctatgagttt
     9001 agtggatatt cggcgaggga tagaagcagc aatcggcgct atgatagaac atggagatca
     9061 ggaactcaag ttggtaggcg gagaaattca ttgatagaaa aaagcttgag gggaaaacct
     9121 tcaagctttt ggacgttttc gagccaatac tgctcggtaa aacataattt tagtgcattg
     9181 gatataaggt aggagtgaaa aactagcaat gccaaaggta atccaattga ggaagtacca
     9241 aggaagaagc tgtaaatcta ggacaaagtg ctggaacttg tagcccttca taaaggaacg
     9301 gctagttttt aggattcgtc ttggtgggac ctgtcctagg tctagactat aacagagaag
     9361 aaattccacc tgtgaatagg cataatactg tggaatatag aggatattcc ctacaatgat
     9421 caagatgaga cttgcaagaa agtagagtcc aaagaccatg aggaaacgct cggtttcaac
     9481 tgatgagaga tctagatttg gaaactcagg atgtagggtg acgaattttt tggctaaaaa
     9541 gctactataa aagaggaggt aaatcccaag taaattaggg atactccata aaaagagata
     9601 gaaacgtttg agaagtaggg tcaaaaaggt ttgagaaaag cgctcctcat caaagagagc
     9661 taggctgttt tttacagatg gctccgtttt agaatctttc atgagtgtca gtgttgcata
     9721 gacggaactg gtcaaaagaa tagtcccgat aaaggagact agtagaggaa agaggtaggc
     9781 ttgaagtatt tggccaagta tgctgaaaaa tggctgttct aaaacagtcc cgtggatccg
     9841 agataaggga ttaagaaaac tagataagat gaccagcata ctgggaagga tatagaggag
     9901 aaagagacgg ggggtgtcag cctgaaaatg ttttgactcc tgacgaattg tttttaaatc
     9961 aatttttgga tagttcattc tcttattata ccatagttct tatacatagt tcgtgacagt
    10021 tcctactttt tttgataaaa tcatacagtg tgtccttggg cacactgtat gaactgggac
    10081 tgtctttccc agcttcggag gtaaaaaatg tcagattcac caatcaaata tcgtttgatt
    10141 aagaaagaaa aacacacagg agctcgtcta ggagaaatca tcactcccca cggtaccttt
    10201 ccgacaccta tgtttatgcc agttgggaca caagccactg tcaaaactca gtcacctgaa
    10261 gaattgaagg agatgggttc gggaattatc ctatcaaaca cctatcatct ctggcttcgc
    10321 cctggagatg aactcattgc acgcgctggt ggtctccaca agttcatgaa ttgggaccag
    10381 cctatcttga cagatagtgg tggttttcag gtttattctt tagcagatag ccgtaatatc
    10441 acagaagaag gagtaacctt taaaaatcat ctaaatggtt ctaagatgtt cctatcccca
    10501 gaaaaagcca tctctattca gaataatctg ggttcagata tcatgatgtc ctttgatgaa
    10561 tgtcctcagt tttatcaacc ttatgactac gttaagaaat cgatcgagcg taccagccgt
    10621 tgggctgagc gtggtttgaa ggctcaccgt cgtccacatg accaaggttt gtttggaatt
    10681 gtgcaaggtg caggatttga agaccttcgc cgccaatcag ctcatgatct tgtcagcatg
    10741 gatttctcag gctactctat cggtggtttg gcagtgggag aaacccatga agagatgaat
    10801 gcggtcttgg actttacaac tcaactgcta cctgaaaata aacctcgtta tctgatgggt
    10861 gtgggagcgc cagatagctt gatcgatggg gtcattcgtg gggtggatat gtttgactgt
    10921 gtcttaccga ctcgaattgc tcgtaacggg acttgtatga ccagtcaagg acgtttggtt
    10981 gtgaaaaatg cccagtttgc tgaggacttt acgccactgg atcctgagtg tgattgttac
    11041 acatgtaata actatacacg cgcttacctt cgtcacctgc tcaaggctga tgaaaccttt
    11101 ggtatccgct tgactagcta ccacaatctt tacttcttgc ttaacttgat gaagcaagtg
    11161 cgacaagcca tcatggatga caatctcttg gaattccgtg agtattttgt ggaaaaatat
    11221 ggctataata agtcaggacg taatttctaa aatggaattg atataagcta aaaatcctaa
    11281 gttttctctt aggatttttc ttcttttttt gatagaataa agtgtacaat gaaaggaaga
    11341 ataaactcgt atgcgcatta aatggttttc cttggttagg attacaggtt tacttttggt
    11401 actcttgtat cacttctttc agacgatctt tcctggagga tttttcgggg tagatgtctt
    11461 tttcacattt tcaggtttcc tgattacagc tctactcatt gaagaatttt ctaaaaacca
    11521 tgagattgat ttgataggat tttttagaag acgcttttat cggattgtgc cacctgtggt
    11581 tttgatggtc ttggtgacca tgccttttac tttcttggtt cgccaagact atgttgctgg
    11641 aattggtggc cagattgcga gcgtcttagg ctttatgacc aacttctatg aactcctaac
    11701 aggtgggagt tatgaatctc agttcattcc tcatttgttt gttcataatt ggagtttggc
    11761 agttgaggtt cactactata ttctttgggg attggcagtt tggttcttat ccaaacaagc
    11821 taaatcaaat ggtcagttga aggggatggt ctttctctta tctgctgttg ccttcttgat
    11881 cagtttcttc tccatgttta ttggtagttt tctagtgacc tcttattcct ctgtttattt
    11941 ctccagttta actcatgtct atccattctt tttgggaagt atgttagcaa ctattgtagg
    12001 cgttcgtcag acgacttccc tcgtcaagca gttggataaa atctgggatt tacgaaagac
    12061 tttggtagtt tttggaggag gctttggttt cctagttctt ttgactttct ttgtcaaatt
    12121 cacttatctt tttgcctatc ttatcggctt cttacttgcc agtcttgcag ctcttgccat
    12181 gattctggcg gcgcgtgtct tacatgaaaa gacacatcat atacaggagc cgaagattat
    12241 cagcttttta gcggatacta gctatgcggt ttatcttttc cattggcctt tctatatcat
    12301 tttctcacag ttgacatcaa atcttcttgc tgtattactg actctgattt gttcttatgg
    12361 ctttgccagt ctgtcattct atgtattgga accttggatt gcaggcaaga acacacctat
    12421 tgtccaaacc cttcgtcccc tgccttatat tcacgcaatt cttgcagcag gtacaggaat
    12481 cttgaccatc attgtctgca cggtgacctt gttggcacca caagtgggag cgtttgagac
    12541 agacttgact gtcaatggct tgaagcaagc tgcaacaaat attggccaga ccaaggtgat
    12601 ggcagaacgg gcagatgcaa acagtttggg aattgctgat ggcactatgt taattggtga
    12661 ctcagtggct ttaagggcaa atacagcact acagacagct cttcctggag cacagattaa
    12721 cgcgcaggtc agcgtaacaa ccaagaccgc aaatgaaatc atgctaaata atagccagaa
    12781 taaattttta cctaagacgg tggtcattgc gactggggta aataatcctg agaattacaa
    12841 ggatgactgg gacagtatcg tgaaaaatct tcctaaggga caccatatga ttttggtgac
    12901 tccttatgag ggagataaga caaaagagac ctatgccatc gttgagaagg ctgctgccta
    12961 tatgagagaa ttggcagaga agacacctta cattacgata gcagattgga atcaagttgc
    13021 gaaagagcat ccagaaattt gggcaggaac agaccaggtt catttcggga gtgagagtag
    13081 cactatcgaa gcaggagcaa aattgtatgc agatacgatt gccacagctt tgcagacagc
    13141 tcaagacaag ccggttaaat caaaataact tgtattaaaa aagagaagag ttggagaaat
    13201 ccagctcttt taaaatatct ccaaaaaata ggtctatacc atttacaaat aaaaaagaaa
    13261 ggtttataat gtaattgaca taataaattg tagaatcaat cttttaagga ggttaacatt
    13321 atgcctaact atattaaagc ggatcagttt ttctacccac acggagttcg tcgaggtggt
    13381 tacttggaac ttgtggacgg caagtttggg aaacatgtag agcagattcc tgaaggggct
    13441 gaggtgattg actatacagg ttatagcatt gccccaggtc ttgtggatac tcatattcat
    13501 ggatatgcag gtgtagatgt gatggacaac aacattgaag gtacattgca tactatgagt
    13561 gaaggacttc ttagtaccgg tgttaccagt ttcttaccca caactttaac agccacttat
    13621 gagcaattgc ttgcagtcac tgaaaatctt ggaaaccatt ataaagaagc aacaggtgct
    13681 aagattcgtg ggatttatta tgaaggtcca tatttcacag aaacttttaa gggggcacaa
    13741 aatccaactt atatgagaga cccgggtgtt gaggagtttc attcttggca aaaagcggca
    13801 aatggcttgc ttaataaaat tgcccttgca ccagaacgtg atggggtggg ggactttgtt
    13861 cgtacagtta cgggcgaagg tgtgacggtt gctcttggac attcaaacgc gacttttgat
    13921 gaagccaaaa aagcagtcga tgctggagcg agtgtttggg tgcatgccta caatggaatg
    13981 cgtgggttga ctcaccgtga attgggtatg gttggagcca tgtaccaatt gccacatacc
    14041 tatgcagagt tgatctgtga tggccaccac gtagatccaa aggcttgcga aattcttatc
    14101 aaacaaaaag gaacagaaaa catcgctctt atcacagact gtatgacagc tgggggattg
    14161 gaagacggag attatatgtt gggagaattc ccagttgtcg ttgcaaatgg aactgcacgc
    14221 ctcaaatcga caggtaactt ggcaggttct atcctcaaac tcaaagatgg tttgaagaat
    14281 gtggtcgaat ggggaattgc gaatccgcat gaagcagtca tgatggccag cttcaaccca
    14341 gctaaatccg ttcacatcga tgatgtctgt ggccaaatcc gtgaaggcta cgacgctgac
    14401 ttcatcgtat tagataaaga tttggaattg gtagcaacct acctagatgg cgtaaaacgt
    14461 tatcaagcat aagagagaaa gcagaagtta gagactaact tctgcttttt tatgcagggt
    14521 actttactgg taaataaaaa gttaaaaaaa atcacaaaaa agcttgaaga aacaaagaaa
    14581 aaggcttaca attgaactat aaatattaca aataaaaaaa cggaggagtg ctttatgaaa
    14641 gcctatactt atgttaaacc aggacttgct tcttttgttg atgtagacaa accagttatt
    14701 cgcaagccaa cagatgctat tgtgcgtatt gtaaaaacca ctatttgtgg aacagacctc
    14761 catattatca aaggggatgt tcctacttgc caaagtggta ccattcttgg ccacgaaggg
    14821 attgggattg ttgaagaagt tggggaagga gtttccaact tcaaaaaagg tgacaaggtc
    14881 ttgatttctt gcgtctgtgc ctgtggtaaa tgctactact gtaaaaaagg aatttatgct
    14941 cactgtgaag acgaaggggg ctggattttc ggtcacttga ttgatggtat gcaggctgaa
    15001 tatctacgtg tccctcatgc agataatact ctttaccata ctccagaaga cttgtcagat
    15061 gaagctttgg ttatgctgtc agacattctg cctactggat atgaaattgg tgtcttaaaa
    15121 gggaaagtag aacctggttg cagcgtagcc attattggtt caggtccagt tggattggct
    15181 gctcttttaa cagcccaatt ctattcacca gctaaattga ttatggtgga cttggatgat
    15241 aaccgtttgg atactgcagt atcctttggt gctactcata aggtaaactc ttcagaccct
    15301 gaaaaagcga taaaagaaat ttatgatttg acagatggtc gcggtgtaga tgtcgctatt
    15361 gaagctgtag ggattcctgc aacatttgat ttctgtcaaa agattatcgg tgtagacgga
    15421 acggttgcca actgtggtgt gcatggtaaa ccagttgaat tcgatttaga taaactttgg
    15481 attcgcaaca tcaatgtaac aactggtttg gtatctacaa atacgactcc acaattgttg
    15541 aaagcacttg aaagtcataa gattgaacca gaaaaattgg taactcacta tttcaaactc
    15601 agtgaaattg aaaaagccta tgaagtcttc agtaaggcag cagaccacca tgccattaag
    15661 gtcattatcg aaaacgatat ctcagaagcc taagtagtaa aaatattttt gtacataagt
    15721 aaatagaaat tcagtcatcc atcagatagc tggatttttt atcaaaaaat taagaaatga
    15781 gcatatttct ttccttgtct ggcggaattg gttataatat acggtacaaa ggaatgaatg
    15841 aatatgtatc gtgttataga aatgtacgga gattttgaac cgtggtggtt cttagaaggt
    15901 tgggaagaag atattgtagc aagtagaaaa tttgaccagt attatgatgc tctcaaatac
    15961 tacaaaactt gctggtttag attggaacaa gaatcccctc tttataaaag tagaagcgac
    16021 ttgatgacca ttttttggga cccggaagac caacgctggt gtgatgaatg tgatgagtat
    16081 ttacaacaat accattcttt ggctcttttg caggatgagc aggttatccc agacgaaaaa
    16141 ctacgctcag gctatgaaaa acaaaccagt caggaaagga atcgttcttg ccgtatgaaa
    16201 ttaaaataga gaaaagtaac ttttttggag ttgctttttt tatttttcta acgctttgcg
    16261 aatagtatag gtgaggaggt aagtatggtt caagaaattg cacaagaaat cattcgttcg
    16321 gctcggaaaa aaggggcgca agacatttat tttgtcccta agttagatgc ctatgagctt
    16381 catatgaggg taggagacga gcgctgtaaa attggtagct atgattttga aaagtttgca
    16441 gccgttatca gtcactttaa gtttgtggcg ggtatgaatg tgggagaaaa aagacgtagt
    16501 caactgggtt cctgtgatta tgcctatgac cagaagatag cgtctctacg tttatctact
    16561 gtaggcgatt atcgggggca tgagagtttg gttatccgtt tgttgcacga tgaggagcag
    16621 gacttgcatt tttggtttca ggatattgaa gaattaggca agcagtacag gcaacgggga
    16681 ctctatcttt ttgctggccc ggttgggagt ggtaagacga ccttgatgca tgaattgtcc
    16741 aagtcactct ttaaaggaca gcaagttatg tccatcgaag atcctgtcga aatcaagcag
    16801 gacgacatgc ttcagttgca gttgaacgaa gcaatcggcc taacctatga aaatctaatc
    16861 aaactttcct tgcgtcatcg accagatctc ttgattatcg gagaaattcg tgacatcgag
    16921 acggcgcgtg cagtggtcag agctagtttg acaggtgcga cagtcttttc aaccattcac
    16981 gccaagagta tccgaggtgt ttatgagcgt ctgctggagt tgggtgtgag tgaagaagaa
    17041 ttggcagttg ttctgcaagg agtctgctac cagagattaa tcgggggagg aggaatcgtt
    17101 gactttgcaa acagagatta tcaagaacac caagcagcca agtggaatga gcaaattgac
    17161 cagcttctta aagatggaca tatcacaagt cttcaggctg agacggaaaa aattagctac
    17221 agctaagcaa aaaaatatca tcaccctatt taacaatctc ttttctagcg gttttcatct
    17281 ggtggagact atctcctttt tagataggag ttccttgttg gacaagcagt gtgtgaccca
    17341 gatgcgtaca ggcttgtctc aggggaaatc attctcagaa atgatggaaa gtttgggatg
    17401 ttcaagtacc attgtcactc agttatctct agctgaagtt catggcaatc ttcacctgag
    17461 tttgggaaag atagaagaat atctagacaa tctggccaag gtcaagaaaa agttaattga
    17521 agtagcgacc tatcctttga ttttgctggg ttttcttctc ttaattatgc tggggctacg
    17581 gaattacctg ctcccacaac tggatagtag caatattgcc acccgaatta tcggtaatct
    17641 gccacaaatt tttctaggca tggtagggct tgtttccgtg cttgcccttt tagcactaac
    17701 tttttataaa agaagttcta agatgagtgt cttttctatc ttagcacgcc ttccctttat
    17761 tggaatcttt gtgcagacct acttgacagc ctattatgca cgtgaatggg ggaatatgat
    17821 ttcacaggga atggagctga cgcagatttt tcaaatgatg caggaacaag gttcccagct
    17881 ctttaaagaa atcggtcaag atctggctca aaccctgaaa aatggccgtg aattttctca
    17941 gacgatagga acctatccgt tctttaggaa ggaattgagt ctcatcatag agtatgggga
    18001 agttaagtcc aagctgggta gtgagttgga aatctatgct gaaaaaactt gggaagcctt
    18061 ttttacccga gtcaaccgca ccatgaattt ggtgcagcca ctggttttta tctttgtggc
    18121 actgattatc gttttacttt atgcggcaat gctcatgccc atgtatcaaa atatggaggt
    18181 aaatttttaa aatgaaaaaa atgatgacat tcttgaaaaa agctaaggtt aaagctttta
    18241 cattggtgga aatgttggtg gtcttgctga ttatcagcgt gcttttcttg ctctttgtac
    18301 ctaatctgac caagcaaaaa gaagcagtca atgacaaagg aaaagcagct gttgttaagg
    18361 tggtggaaag ccaggcagaa ctttatagct tagaaaagaa tgaagatgct agcctaagaa
    18421 agttacaagt agatggacgc atcacggaag aacaggctaa agcttataaa gaataccatg
    18481 ataaaaatgg aggagcaaat cgtaaagtca atgattaagg cctttaccat gctggaaagt
    18541 ctcttggttt tgggtcttgt gagtatcctt gccttgggct tgtccggctc tgttcagtcc
    18601 acttttgcgg cggtagagga acagattttc tttatggagt ttgaagaact ctatcgggaa
    18661 acccaaaaac gcagtgtagc cagtcagcaa aagactaatc taaatttaga tgggcagacg
    18721 cttagcaatg gcagtcaaaa gttgacagtt cctaaaggaa ttcaggcacc atcaggccaa
    18781 agtattacat ttgaccgagc tgggggcaat tcgtccctgg ctaaggttga atttcagacc
    18841 agtaaaggag cgattcgcta tcaattatat ctaggaaatg gaaaaattaa acgcattaag
    18901 gaaacaaaaa attagggcag tgattttact ggaagcagta gtcgctctag ctatctttgc
    18961 cagcattgcg accctccttt tgggacaaat tcaaaaaaat aggcaagagg aagcaaaaat
    19021 cttgcaaaag gaagaagtct tgagggtagc taagatggcc ctgcagacgg ggcaaaatca
    19081 ggtaagcatc aacggagttg agattcaggt attttctagt gaaaaaggat tggaggtcta
    19141 ccatggttca gaacagttgt tggcaatcaa agagccataa ggtcaaggct tttaccttgt
    19201 tagaatccct acttgccctc attgtcatca gtgggggatt actccttttt caaactatga
    19261 gtcagctcct catttcagaa gttcgctacc agcaacaaag cgagcaaaag gagtggctct
    19321 tgtttgtgga ccaacttgag gcagaattag accgttcgca gttcgaaaaa gtagaaggca
    19381 atcgcctata catgaagcaa gatggcaagg acatcgccat cggtaagtca aagtcagacg
    19441 attttcgtaa aaccgatgct agtggacggg ggtatcagcc tatggtttat ggcctcaaat
    19501 cagctcagat tacagaggac aatcaactgg ttcattttcg tttccagttt caaaaaggct
    19561 tagaaaggga gttcatctat cgtgtggaaa aagaaaaaag ttaaggcagg tgttctcctc
    19621 tacgcagtca ccatagcagc catctttagt cttttgttgc aattttactt gaaccgacaa
    19681 gtcgcccact atcaagacta tgctttgaat aaagaaaaat tggttgcttt tgcaatggct
    19741 aaacgaacca aggataaagc cgagcaagaa agtggggaac aggtctttaa tctaggtcag
    19801 gtaagctatc aaaacaagaa aacaagcttg gtgacgactg ttcgtacgtc taagagccaa
    19861 tatgagtttc tgtttccttc agtcaaaatc aaagaagaga aaagagataa aaaggaagag
    19921 gtagcgactg attcaagcga aaaagcggag aaaaaatcag aagagaagcc tgaaaagaaa
    19981 gagaattcat agtcaattca actataatgc gttgaatcca gaatagtcca ctgtagtttc
    20041 tagaaaattg ctggaaatgg atgttaagct ccaattcatt tgtttatatc ttatttcagt
    20101 ttactatact ttgtgctaaa ttaaagatat gaaacatgat tttaaccaca aagcagaaac
    20161 tttcgattcc cctaaaaata tcttcctcgc aaacttggta tgtaaagcag ccgagaaaca
    20221 gattgatctt ctatcagaca aagaaatttt agatttcggt ggtggcacgg gtctattagc
    20281 tttgccccta gccaagcagg ctaagtcagt tactcttgta gacatttctg agaaaatgtt
    20341 ggagtaagct cgtttgaaag cggagcagca agcaatcaag aatatccagt ttttggagca
    20401 agatttaccg aaaaatccct tggagaaaga gtttgattgc cttgctgtta gtcggcttct
    20461 tcatcatatg cctgatttgg atgcggatct ctcactgttt catcaacatt tgaaggaaga
    20521 taggaaactc atcattgctg attttaccaa gacagaagct aatcatcatg gatttgattt
    20581 agctgaactg gaaaacaagc taattgagca tagtttttca tctgtgcata gtcagattct
    20641 ctatagcgct gaagacctgt ttcaagggaa tcactcagaa ttctttttaa cagtatccca
    20701 aaaatcactc gcctagtcag ggagtgattt ttctataagg atggaaaaaa gaagggaaat
    20761 ttgataagat aggaatatgg attttgaaaa aattgaacaa gcttatatct atttactaga
    20821 gaatgtccaa gtcatccaaa gtgatttggc gaccaacttt tatgacgcct tggtggagca
    20881 aaatagcatc tatctggatg gtgaaactga gctaaaccag gtcaaagaca acaatcaggc
    20941 ccttaagcgt ttagcactac gcaaagaaga atggctcaag acctaccagt ttctcttgat
    21001 gaaggctggg caaacagaac ccttgcaggc caatcaccag tttacgccag atgctattgc
    21061 cttacttttg gtatttattg tggaagagtt gtttaaagag gaggaaatta ctatcctcga
    21121 aatgggttct gggatgggaa ttctaggcgc tattttcttg acctcgctta ctaaaaaggt
    21181 ggattacttg ggaatggaag tggatgattt gctgattgat ctggcagcta gcatggcaga
    21241 tgtaattggt ttgcaggctg gctttgtcca aggagatgcc gttcgcccac aaatgctcaa
    21301 agaaagcgat gtggtcatca gtgacttgcc tgtcggctat tatcctgatg atgccgttgc
    21361 gtcgcgccat caagttgctt ctagccaaga acatacttac gcccatcact tgctcatgga
    21421 acaagggctt aagtacctca agtcagacgg atacgctatt tttctagctc cgagtgattt
    21481 gttgaccagt cctcaaagtg atttgttaaa agaatggctg aaagaagagg cgagtctggt
    21541 tgctatgatt agtctgcctg aaaatctctt tgctaatgcc aaacaatcta agactatttt
    21601 tatcttacag aagaaaaatg aaatagcagt agagcctttt gtttatccac ttgctagctt
    21661 gcaagatgca agtgttttaa tgaaatttaa agaaaatttt caaaaatgga ctcaaggtac
    21721 tgaaatataa aatagatttt gttataatag ttgaaaacgc ttaaaaaggg gtatcatgtt
    21781 atgacaaaaa caattgcaat caatgcagga agttcaagtt tgaaatggca attatactta
    21841 atgccagaag aaaaagtatt ggcgaaaggt ttgattgaac gtatcggttt gaaagattca
    21901 atttcaactg taaaatttga cggccgttct gaacaacaaa ttttggatat tgaaaatcat
    21961 atacaagccg ttaaaatttt attggatgac ttgattcgtt tcgatattat caaggcttat
    22021 gacgagatta caggtgttgg acatcgtgtt gttgctggtg gagaatattt caaagaatca
    22081 acagttgttg agggagatgt tttagaaaaa gttgaagagt tgagtttgtt ggctcctcta
    22141 cacaacccgg ccaatgcagc aggtgttcgt gccttcaagg aattgttgcc agacattacc
    22201 agtgtagttg tttttgatac ttccttccac acaagtatgc cagagaaagc ttatcgctac
    22261 cctctaccaa caaaatatta cacagaaaac aaggttcgta aatacggtgc tcatggtaca
    22321 agtcaccagt ttgtagcagg agaagctgca aaactcttgg gacgtccatt agaagacttg
    22381 aagttaatta cctgtcatat tggtaacgga ggctcaatta cagctgtgaa agccggcaaa
    22441 tctgtagaca cttctatggg gttcactcct cttggtggta ttatgatggg aacgcgtaca
    22501 ggggatattg atccagctat cattccttat ttaatgcaat atacagagga ttttaacaca
    22561 ccagaagata tcagtcgtgt tcttaaccgt gaatcaggtc ttttgggagt ttctgctaat
    22621 tctagcgata tgcgcgatat agaagcagct gtagcagaag ggaatcacga ggctagcttg
    22681 gcttatgaaa tgtatgttga ccgtatccaa aaacatatcg gtcagtacct tgcagtgcta
    22741 aatggagcag atgccattgt tttcacagca ggtgtcggtg aaaatgcaga gaatttccgt
    22801 cgtgatgtaa tctcagggat ttcgtggttt ggttgtgatg ttgatgatga aaagaatgtc
    22861 tttggcgtta caggagacat ctcaacagag gcagctaaaa tccgtgtctt ggttattcca
    22921 acagatgaag aattagtcat tgcccgtgac gttgaacgct tgaaaaaata agtgaaacta
    22981 aaaaaatatt caatacaagg agttgggaaa gttatttttc cagcttcttt ttctgatgaa
    23041 attgtccaaa accttgctat gattggcttt tttgaaaaat atggtataat agtagtaatt
    23101 taatagatgg agttgagttt tgaagaaaaa ctttcgtgta aaaagagaga aagattttaa
    23161 ggcgattttc aaggagggga caagttttgc taatcgcaaa tttgtggtct accaattaga
    23221 aaaccagaaa aaccgttttc gagtaggtct atcagttagc aaaaaactgg ggaatgccgt
    23281 cactagaaat caaattaagc gacggattcg gcatattatc cagaatgcaa aagggagtct
    23341 ggtagaagat gtcgactttg ttgtcattgc tcgaaaagga gtcgaaacct tgggatacgc
    23401 agagatggag aaaaatctac tccatgtatt aaaattatca aagatttacc gggaaggaaa
    23461 tgggagtgaa aaagaaacta aagttgacta gtttgctagg actgtctctg ttaatcatga
    23521 cagcctgtgc gactaatggg gtaactagcg atattacagc cgaatcggct gatttttgga
    23581 gtaaattggt ttacttcttt gcggaaatca ttcgcttttt atcgtttgat attagtatcg
    23641 gagtggggat tattctcttt acggtcttga ttcgtacagt cctcttgcca gtctttcagg
    23701 tgcaaatggt ggcttctagg aaaatgcagg aagctcagcc acgcattaag gcgcttcgag
    23761 aacaatatcc aggtcgagat atggaaagca gaaccaaact agagcaggaa atgcgtaaag
    23821 tatttaaaga aatgggtgtc agacagtcag actctctttg gccgattttg attcagatgc
    23881 cggttatttt ggccctgttc caagccctat caagagttga ctttttaaag acaggtcatt
    23941 tcttatggat taaccttggt agtgtggata caacccttgt tcttccgatt ttagcagcag
    24001 tattcacctt tttaagtact tggttgtcca acaaagcttt gtctgagcga aatggcgcta
    24061 cgactgcgat gatgtatggg attccagtct tgatttttat ctttgcagtt tatgcgccag
    24121 gtggagtcgc cctatactgg acagtgtcta atgcttatca agtcttgcaa acctatttct
    24181 tgaataatcc attcaagatt atcgcagagc gcgaggccgt agtacaggca caaaaagatt
    24241 tggaaaatag aaaaagaaaa gccaagaaaa aggctcagaa aacgaaataa ataaggagga
    24301 atctggtagt ggtagtattt acaggttcaa ctgttgaaga agcaatccag aaaggattga
    24361 aagaattaga tattccaaga atgaaggctc atatcaaagt catttctagg gagaaaaaag
    24421 gctttcttgg tctatttggt aaaaaaccag cccaagtgga tattgaagcg attagtgaaa
    24481 cgactgttgt caaagcaaat caacaggtag taaaaggcgt tccgaaaaaa atcaatgatt
    24541 tgaacgagcc tgtgaagacg gttagtgaag aaaccgttga ccttggtcat gtggttgatg
    24601 ctattaaaaa aatagaggaa gaaggtcaag gtatttctga tgaagtcaag gctgaaatct
    24661 taaaacatga aagacatgcc agcactatct tagaagaaac tggtcacatt gagattttaa
    24721 atgaacttca aatcgaggaa gcgatgaggg aagaagcagg cgctgatgac cttgaaactg
    24781 agcaagacca agctgaaagt caagaactag aagacttggg cttgaaagtt gaaacgaact
    24841 ttgatattga acaagtagct acggaagtaa tggcttatgt tcaaacgatt attgatgaca
    24901 tggatgttga ggctacactt tcaaatgatt ataaccgtcg tagcatcaat ctacaaattg
    24961 acaccaacga accaggtcgt attatcggct accatggtaa agtcttgaag gccttgcaac
    25021 tgttggctca aaattatctt tacaaccgct attccagaac cttctacgtt acaatcaatg
    25081 tcaatgatta tgtcgaacac cgtgcagaag tcttgcagac ctatgcgcaa aaattggcga
    25141 ctcgtgtttt ggaagaaggg cgcagtcata aaacagatcc aatgtcaaat agcgaacgca
    25201 agattatcca tcgtattatt tcacgtatgg atggcgtgac tagttactct gaaggtgatg
    25261 agccaaatcg ctatgttgtt gtagatacag aataagtaaa atcaggttta tcctgatttt
    25321 ttgctagtta gaggaggtta aactgatgtt gaataagata agagactatt tagactttgc
    25381 tggtttgcag taccgtaatc ctgataaagc gggagcagag cgagagaaga tgctggcatt
    25441 ccgccacaaa ggacaagagg cccgaaaggt ttttacagaa ctggccaaag cctttcaagc
    25501 aagccatcca gaatggcaac tccaacagac tagccagtgg atgaatcagg cccagcgttt
    25561 gagaccacat ttttgggttt atctacagag agacggacaa gtgacagaac ctatgatggc
    25621 cttacgtttg tatgggacat ctactgactt tggaatttct ttggaagtca gtttcatcga
    25681 acgtaagaag gatgagcaaa cactgggcaa gcaggccaaa gttttagaca ttccaaccgt
    25741 taaagggatt tattatctaa cctactctaa tggtcaaagt caacggtggg aggcgaatga
    25801 agaaaagcgt cgtactttac gcgagaaggt gagaagtcaa gaagttcgaa aagttttagt
    25861 gaaggtagat gttcctatga cagaaaattc gtctgaagaa gaaatcgtag aaggcttatt
    25921 gaagtcttat tctaaaattc ttccctatta tctagctacg agaaaataag ataatttgta
    25981 aaacatcata aatcatacag tccaagagtg aacagtccgc tgtgtaattc ttggtctttt
    26041 tgtttgcgct ttcgcattat ataataaact tacaaaaata attcaaaagg agaacaatta
    26101 tggaagtcgt ttcaagtgtt ctaaattggt tttctagcaa tattttgcag aatcccgcat
    26161 ttttcgtagg tttattggtg ttgataggat atgcactttt gaaaaaacct gcccatgacg
    26221 ttttttcagg gtttgttaaa gcaacagtag ggtatatgtt gcttaacgtg ggtgctggtg
    26281 gtttggttac aacctttcgt ccaatcttag cagctcttaa ctacaaattc caaattggtg
    26341 cagcggttat cgacccttac tttggacttg ctgcagcaaa caacaaaatt gtagcagagt
    26401 ttccagattt tgttggaact gcaactacag ctctattgat tggttttgga ataaatatct
    26461 tgctcgtagc tcttcgaaag attacgaagg taagaaccct ctttattact ggtcacatca
    26521 tggtacaaca agctgcaaca gtatctctta tggttctatt cttagtacca caattgcgca
    26581 atgcttacgg tacagcagcg attggtatca tctgtggact ttactgggca gttagttcaa
    26641 atatgactgt tgaggcaact caacgcttga ctggtggtgg cggatttgcg attggtcacc
    26701 aacagcaatt tgcaatctgg tttgtagata aagtagcagg acgctttggt aagaaagaag
    26761 aaagtttaga caatcttaaa ttacctaagt tcctctcaat cttccacgat acagttgttg
    26821 catctgctac cttgatgctc gtattcttcg gagccattct tttaatcttg ggtccagaca
    26881 ttatgtctaa taaagaagtc atcacttcag gaactctatt caatcctgct aaacaagatt
    26941 tctttatgta cattatccaa acagccttta ccttctcagt ttacttgttc gttttgatgc
    27001 aaggtgtccg aatgttcgta tctgagttga caaacgcctt ccaaggtatt tcaaacaaat
    27061 tgttgccagg ttcattccca gcggttgacg ttgcagcttc ttatggattt ggttctccaa
    27121 atgctgtctt gtcaggattt acctttggtt tgattggtca attgattaca attgttttgc
    27181 tcatcgtctt taaaaatccg attcttatta ttacaggatt tgtaccagtg ttctttgaca
    27241 atgcagccat tgcggtctac gctgataaac gcggcggatg gaaagcggct gttatccttt
    27301 cctttatatc aggtgtcctt caagttgctc taggagctct ttgtgtggcc cttctcgatt
    27361 tggcatctta tggtggctac catggaaata tcgactttga attcccatgg cttggatttg
    27421 gatatatctt caaatacctt ggtattgttg gttatgtact tgtgtgtctc ttcttgcttg
    27481 ttattcctca acttcaattt gccaaagcaa aagataaaga gaaatattac aacggtgaag
    27541 ttcaagaaga agcttagtat ctagaaaagg agaaataaaa tggttaaagt attagcagcg
    27601 tgcggaaatg gaatgggttc atcaatggtt atcaagatga aggttgaaaa tgctctccgt
    27661 aagcttaatc aaacagattt tacagtcaat tcatgcagtg tcggtgaagc taaaggttta
    27721 gcagtaggat atgacatcgt aatcgcttct cttcatttga ttcaagaatt ggaagggcga
    27781 actaatggga agttaattgg acttgataac ttgatggatg ataaagaaat caccgaaaaa
    27841 ctcagtcaag cactacagta aaaggttgga gggggctgga cagaaactga gagttatcgt
    27901 ttctgtcctt ctccctcttt aaataaagga ggcagatatg aatttaaaac aagctttaat
    27961 tgacaatgac tcgatccgac taggtttaga ggctaacaat tggaaagaag cagtcaaggt
    28021 agcagtagat cccttaattg aaagtggggc aattttgcca gagtattacg atgctatcat
    28081 tgaatcgact gaagagtatg ggccttacta tatcttgatg ccaggtatgg ctatgcccca
    28141 cgctagacct gaagctggtg tgcaaagtga tgccttttca ttgattacct tacaaaatcc
    28201 tgttgtattt tcagatggga aagaggtatc tgttttgttg gcactagcag caacaagctc
    28261 aaaaattcac acaagtgtag ccattccaca aattattgcc ctgtttgaat tagacgattc
    28321 tattgcacgt ttacaggctt gccagactaa agaagatgtc ttggctatga ttgaagaatc
    28381 taaggatagc ccttatctcg aaggattgga tttggaaagt tagaaagagg aataaagaaa
    28441 tgacaaaaag aatacctaat ttacaagttg cattagacca ttcagacttg caaggagcga
    28501 ttaaagcagc tgtttctgtt ggtcaggaag tagatattat cgaagctgga actgtttgct
    28561 tgcttcaagt tggaagtgaa ctggctgaag tcttgcgtag ccttttccca gataagatta
    28621 ttgtggcaga cacaaaatgt gctgatgctg gtggaacagt tgctaaaaat aatgcggttc
    28681 gtggagcaga ctggatgact tgtatctgtt gtacaaccat ccctactatg gaagcagctc
    28741 taaaggctat caagactgaa cgaggagaac gaggcgaaat ccagatcgag ctttatggcg
    28801 attggacttt tgaacaagct cagctttggc tagatgcagg tatttcacaa gctatttatc
    28861 accaatctcg tgatgctctt cttgctggtg aaacttgggg tgaaaaagac cttaataagg
    28921 ttaaaaaact cattgacatg ggcttccgtg tatctgtaac aggtggtcta gatgtagata
    28981 ctctcaaact ctttgaaggt gttgatgtct ttacctttat cgcaggtcgt ggaattacag
    29041 aggctgcgga tccagcagga gcagcgcgtg ccttcaagga tgaaatcaaa cgaatttggg
    29101 ggtaaatcat ggtacgtcca attggaattt atgaaaaggc aaccccaaca cactgtactt
    29161 ggctagaacg tttaaatttt gccaaggagt taggctttga ttttgtcgag atgtctattg
    29221 acgaacgtga cgagcgttta gcaagacttg actggagtaa ggaagaacgc ttggaagttg
    29281 tcaaagcaat ctatgaaact ggtgttcgta ttccttctat ctgtttttca ggccatcgtc
    29341 gctacccatt gggttcaaaa gatccagttc tagaggaaaa atctctagaa ctcatgaaaa
    29401 aatgtatcga attagctcaa gacttgggag ttcgtacgat tcaattagct ggttacgatg
    29461 tttactatga ggaaaagtca ccccagacac gccaacgttt tatcaaaaat ttgagaaaag
    29521 cctgtgactg ggctgaagaa gctcaggtgg tacttgctat tgaaattatg gatgatcctt
    29581 tcatcaatag catcgaaaaa tatttggcta tagaaaaaga gattgactct cccttcctct
    29641 ttgtatatcc agatattggt aatgtgtctg catggcataa tgatatctat agtgagtttt
    29701 atcttggtca tcatgccatc gcagctctcc atctcaagga tacttatgca gtgacagaaa
    29761 gttcaaaggg ccagttccga gatgtacctt ttgggcaagg ttgtgtcaaa tgggaagaag
    29821 ctttcgatat tttaaaggaa accaattata atggaccttt cctaatcgaa atgtggtctg
    29881 aaaattgtga aacagtagaa gaaacacgcg cagccattca agaggcgcaa gcttttctct
    29941 atccactcat taagaaagca ggtttgatgt aagatgaatc aagtaatcaa tgctatgcgt
    30001 aaacgagttt gtgatgccaa tcaatcattg ccaaaacatg gacttgtcaa atttacctgg
    30061 gggaatgtat ctgaagtcaa tcgcgaactc ggtgtcattg ttatcaaacc atcaggcgtg
    30121 gattatgacg aattgacacc tgaaaacatg gtagtgactg atctagatgg taagatccta
    30181 gaaggggatt taagaccatc ttccgacctc ccaactcatg tgcaattata taagacttgg
    30241 tcagaaattg gtagtgtggt tcacacccat tcgacagaag ctgttggttg ggctcaggca
    30301 ggtcgtgata ttcctttcta cggaacaacc catgcagatt atttctacgg ttcaatccct
    30361 tgcgcccgta gtttgaccaa ggacgaagta gaagtggcct atgaaaaaga tactggcctg
    30421 gttatcgtag aagagtttga acatcgcgga cttaacccgg ttgaagtacc aggaattgtt
    30481 gtacgcaatc acggtccatt cacctggggc aaaaatccag agaatgctgt ttatcactct
    30541 gtcgtactag aggaagtatc aaagatgaat cgctttacag aacaaatcaa tccaagagtt
    30601 ggacctgctc cccagtacat actagaaaaa cactaccaac gtaaacatgg accaaatgct
    30661 tattatggtc aaaagtaaga acgatgaagg aggagaaaaa gataaattta gctcctcttt
    30721 ttacatttga tttttattga gagtaaagtt ggagttgaag taattttaaa agatttttta
    30781 gaaatagcgc ttgatatata tatggtaaaa taaaaagaat tgctgtgata tcaatagatt
    30841 tgggggattt tttaatatgg tactggataa ggcaagttgt gatttgcttc aatatttgat
    30901 ggatcaagaa acgtccaaaa cgattatggc gatttcgaaa gatttgaaag agtcaagaag
    30961 gaaaatttat tatcacattg acaaaatcaa tgctgctctg ggtgacgagg cgcttcacat
    31021 cattagtatt ccacgaattg gtattcactt aacggaagag cagagagatg cttgttgtaa
    31081 actattatcg gaagtagatt cgtacgatta tatcatgagt gcgcatgaac gtatgatgat
    31141 aatgttacta tggataggta tttctaaaga acgtattacg attgaaaaat tgatagagtt
    31201 aacagaggta tctaggaata ctgttctcaa tgatttgaat agtattcgtt atcaactaac
    31261 tttggaacaa tatcaggtga tcttgcaagt gagcaagtca cagggataca accttcatgc
    31321 ccaccctctt aataaaattc agtatcttca atcgcttcta tatcatattt ttatggaaga
    31381 aaatgccact tttgtatcta ttttagaaga taagatgaaa gagaggttag atgatgagtg
    31441 tttgctttct gttgaaatga accaattttt taaggaacag gttcctttag ttgaacaaga
    31501 tttagggaag aaaataaacc atcatgaaat aacttttatg ttgcaggttc taccttattt
    31561 gctgttaagc tgtcataatg ttgaacagta tcaagaaaga catcaggata tagagaaaga
    31621 attttctttg ataagaaaaa gaatagagta tcaggtgtct aagaaattag gagaacggtt
    31681 gtttcaaaag tttgaaattt ctttgtcagg acttgaagtt tctcttgtag ctgttctcct
    31741 cctctcctat cgtaaagatt tggatattca tgcagaaagt gatgattttc ggcaattaaa
    31801 acttgcttta gaagaattta tctggtattt tgaatcacaa atccgaatgg agattgagaa
    31861 caaggatgat ttgttacgaa atttgatgat ccactgtaaa gccttgttat ttagaaagac
    31921 ttacggtatt ttttctaaaa atcctctaac aaaacaaatt cgatccaagt atggagaatt
    31981 atttttagtc actagaaaat ctgcggaaat tttagaagga gcatggttta ttcggctaac
    32041 agacgatgat attgcctatt tgacgattca tattggagga tttttaaaat atacaccatc
    32101 atctcaaaaa aatatgaaaa aagtttatct cgtttgtgat gaaggtgttg cggtttcgag
    32161 acttttgctg aaacaatgca aactttattt tccaaatgag caaattgaca ctgtatttac
    32221 aacagaacaa tttaagagtg tggaagatat tgcacaagtt gatgtagtga ttactactaa
    32281 tgatgatttg gatagcagat ttccgatttt aagggttaat cctatccttg aagcagaaga
    32341 tattttgaaa atgctagact atcttaaaca caatatattt cgtaataaga gcaaaagttt
    32401 cagtgaaaat ctttctagtc ttatttcgtc ttatattgta gacagcaagt tggctagtaa
    32461 gttccaagaa gaggttcaaa cacttataaa tcaagaaata gtagttcaag cttttttgga
    32521 agatatttga aggacagtcc aatgatgaac acaaacctgt gtttttcttg gtctttttta
    32581 gtgttttgaa gggtggtata ctaatctcaa agataacaat tatatccaaa ggaggcaaca
    32641 tatgccaaac gtcaaagaaa ttacaagaga gtcatggatt ttagccactt tcccagagtg
    32701 gggaacatgg ttgaacgaag aaatcgaaga agaagtcgta cctgaaggca actttgccat
    32761 gtggtggcta ggcaactgtg gtacttggat taagacacca gctggtgcta acgttgtcat
    32821 ggacctttgg tcaaaccgtg gaaaatcaac caaaaaagtg aaagatatgg ttcgtgggca
    32881 ccaaatggca aatatggcag gtgttcgtaa gctgcaacca aacttgcgtg ttcagccaat
    32941 ggttatcgat ccatttgcta tcaacgaact agactattac ttagtttcac acttccacag
    33001 tgatcatatc gacccataca cagctgcagc aattctcaat aatcctaagt tagagcatgt
    33061 taagtttatc ggtccttacc actgtggacg aatctgggaa ggatggggtg ttccaaaaga
    33121 acgtatcatc gttgttaaac caggtgacac tatcgaatta aaagatatga agattcatgc
    33181 agtagaatca tttgaccgta cttgcttggt aactctccca gtgaacggtg ctgatgagac
    33241 aggcggtgaa cttgctggct tggctgttac agatgaagaa atggctcaaa aggctgttaa
    33301 ctatatcttt gaaacaccag gtggaaccat ctatcatggt gcagattctc acttctcaaa
    33361 ctattttgca aaacatggta aagactttaa aattgatgtt gctttgaata actatggtga
    33421 aaatccggta ggtatccaag acaaaatgac atctatcgac cttcttcgta tggcagaaaa
    33481 tctgcgtacc aaagtcatta tcccagttca ctatgatatc tggtctaact tcatggcttc
    33541 tactaatgag attctagaac tttggaaaat gcgaaaagat cgcttgcaat acgatttcca
    33601 tccatttatc tgggaagttg gcggtaagta cacttatcct caagatcaac acttagtaga
    33661 ataccatcat ccacgtggtt ttgatgattg ttttgaacaa gactctaaca ttcaatttaa
    33721 agctttgcta taatataaaa atattctttg gaggttatcc gtatgttgca tgatacggat
    33781 aattttcata taatagtaaa atagaatgtg tgattcaata atcacctcaa atagaaagga
    33841 aattctatgt caaatctatc tgttaatgca attcgttttc taggtattga cgccattaat
    33901 aaagccaact caggtcatcc aggtgtggtt atgggagcgg ctccgatggc ttacagcctc
    33961 tttacaaaac aacttcatat caatccagct caaccaaact ggattaaccg cgaccgcttt
    34021 attctttcag caggtcatgg ttcaatgctc ctttatgctc ttcttcacct ttctggtttt
    34081 gaagatgtca gcatggatga gattaagagt ttccgtcaat ggggttcaaa aacaccaggt
    34141 cacccagaat ttggtcatac ggcagggatt gatgctacga caggtcctct agggcaaggg
    34201 atttcaactg ctactggttt tgcccaagca gaacgtttct tggcagccaa atataaccgt
    34261 gaaggttaca atatctttga ccactatact tacgttatct gtggagacgg agacttgatg
    34321 gaaggtgtct caagcgaggc agcttcatac gcaggcttgc aaaaacttga taagttggtt
    34381 gttctttatg attcaaatga tatcaacttg gatggtgaga caaaggattc ctttacagaa
    34441 agtgttcgtg accgttacaa tgcctacggt tggcatactg ccttggttga aaatggaaca
    34501 gacttggaag ccatccatgc tgctatcgaa acagcaaaag cttcaggcaa gccatctttg
    34561 attgaagtga agacggttat tggatacggt tctccaaaca aacaaggaac taatgctgta
    34621 cacggcgccc ctcttggagc agatgaaact gcatcaactc gtcaagccct cggttgggac
    34681 tacgaaccat ttgaaattcc agaacaagta tatgctgatt tcaaagaaca tgttgcagac
    34741 cgtggcgcat cagcttatca agcttggact aaattagttg cagattataa agaagctcat
    34801 ccagaactgg ctgcagaagt agaagccatc atcgacggac gtgatccagt cgaagtgact
    34861 ccagcagact tcccagcttt agaaaatggt ttttctcaag caactcgtaa ttcaagtcaa
    34921 gatgccttga atgttgtggc agctaaatta ccaacctttc taggtggatc agctgacctt
    34981 gctcactcaa acatgactta tatcaagacg gatggacttc aagacgatgc caatcgcttg
    35041 aatcgtaaca ttcagtttgg tgttcgtgaa tttgcaatgg gaacaatctt gaacgggatg
    35101 gcccttcatg gtggacttcg tgtatacggt ggaactttct tcgtcttctc tgactatgtg
    35161 aaggcagctg tccgcttgtc agccttacaa ggacttcctg tgacttatgt ctttacccat
    35221 gattcaatcg cagttgggga agatggtccg actcatgaac cagttgagca tttagcaggt
    35281 cttcgtgcta tgccaaatct aaatgttttc cgtccagcag atgcgcgtga aacgcaagca
    35341 gcttggtacc ttgcagtgac aagtgagaaa acaccaactg cccttgtctt gacacgtcaa
    35401 aatttgactg ttgaagatgg aacagacttc gacaaggttg ctaaaggtgc ttatgttgta
    35461 tatgaaaatg cagccgactt tgataccatc ttgattgcga caggttcaga ggttaatctt
    35521 gctgtctcag ctgctaaaga attggctagt caaggcgaaa aaatccgcgt agtcagcatg
    35581 ccatctacag atgtctttga taaacaagat gcagcttaca aggaagaaat tcttccaaat
    35641 gcagtccgcc gtcgtgttgc agtcgaaatg ggtgcaagtc aaaactggta caaatatgtt
    35701 ggtctcgatg gtgccgttct aggtattgat accttcggag cctctgcccc agcaccaaaa
    35761 gtattggcag aatatggctt tactgtagaa aatcttgtaa aagttgttcg aaacttgaaa
    35821 taatcctaaa aatcagggcg taagctctgg tttttcttac cagaaaagta aggtacaatc
    35881 ttgtaaaagt agctgaaatt tgatatagta gtcctatgta aaagacaaag gagaaaacaa
    35941 tgaatccaaa tattactttt ttaatcatgc ttgtaggtat gatggccttg atgttcttta
    36001 tgcaacgttc tcaaaagaaa caagctcaaa agcgtatgga aagcttaaat aaactacaaa
    36061 aaggctatga agtgattaca atcggtggac tttatggaac agtcgatgaa gtagatacgg
    36121 agaagggaac aatagttctt gacgtagatg gagtttactt gacttttgaa ctagctgcta
    36181 tcaagacagt attaccgctg aaagaaacag cttcactaga aggcgcaatt gaaaaataag
    36241 acgggatcac gaactcccgt tttctataaa agaaaggaaa tgggatgaaa aaattagtct
    36301 ttgtctgtct gggaaatatt tgccgtagcc ctatggccga gtttgttatg aaatcaatga
    36361 cagataacta cgaaatccaa agtcgagcaa cttcctcttg ggaacatggc aatccgattc
    36421 ataaggggac tcagggaatt tttcaagagt atgagattcc ttatgacaag aacaagacat
    36481 cgcttcagat tagtaaggaa gattttgaag cctttgatta tattatcgga atggacgctt
    36541 caaatatttc tgacttacgt cagatgtgtc cagtagactg tcaagataag atttactcat
    36601 tttcatctga aagtgttcca gacccttggt atacaggaga ttttgaagaa acctatcgac
    36661 gtgttcaaga gggctgtcaa gcttggttag aacgtttaga aaaggagagt taaggtggaa
    36721 aatcttacga atttttacga aaagtatcgt gtctatctga ctcgtccacg tttagagctt
    36781 ttggcagtag ttaccattgt tttctgtgct gtactcgtct tttttctaaa tattccagga
    36841 aaaggtgtct taaaactcga taatggaacg attgtttatg atggcagtct tgtccgcggt
    36901 aaaatgaatg gccaaggtac cattaccttc caaaatggag accaatatac aggtggcttc
    36961 aacaatggag ccttcaacgg aaaaggtacc tttcaatcta aagaaggctg gacctacgaa
    37021 ggtgattttg taaatggtca ggctgaagga aaagggaaac taacaacaga acaagaagtc
    37081 gtttatgaag gaacttttaa acaaggcgtt tttcaacaaa aataaagcct ccttatcaaa
    37141 ggaggtatta ttagaatcgc aaggtaagcg cttacctgca aatccctttc tttccaaatc
    37201 cctcttccaa gcaagtttgt gaaataaaaa atatttgaaa taaatttcac aaacttcaaa
    37261 gataaaacct gataagaaaa gaaaatgaga aaagtttcac aagagtttaa aaattctttg
    37321 tgaaatgttt atgaaactgt ttacaaagtt gaaataatgc gttataataa acttgtgaaa
    37381 aaattaacaa aggatatcgt tccttgaaag ctatggagga aaatatggct gataaaaaaa
    37441 ctgtgacacc agaggaaaag aaactcgttg ctgaaaaaca cgtagatgag ttggttcaaa
    37501 aagctctagt tgcccttgaa gaaatgcgta aattggatca agaacaagtt gactacatcg
    37561 ttgccaaagc atcagtagca gctttggatg cccacggaga attggcttta catgcctttg
    37621 aagaaacagg acgtggtgta tttgaagaca aagcaactaa gaacttgttt gcctgtgaac
    37681 acgtagtaaa caacatgcgc cacactaaga cagttggcgt tatcgaagaa gacgatgtaa
    37741 caggattgac tcttattgct gaaccagttg gtgttgtttg tggtattact ccaacaacaa
    37801 acccaacatc aacagcaatc ttcaaatcat tgatttcatt gaagacacgt aacccaatcg
    37861 tctttgcctt ccatccatca gcacaagaat catctgctca tgcagctcgt atcgtccgcg
    37921 atgcagctat cgcagctggt gctcctgaaa actgtgtgca atggattact caaccatcta
    37981 tggaagcaac aagtgccctt atgaaccacg aaggtgttgc gacaatcctt gcaacaggtg
    38041 gtaatgccat ggttaaggcg gcttattcat gtggtaaacc agctcttggg gtaggtgccg
    38101 gaaacgttcc agcttatgtt gaaaaatcag caaacattcg tcaagcagca cacgatatcg
    38161 tcatgtctaa atcatttgat aacggtatgg tctgtgcatc tgaacaagca gttatcattg
    38221 ataaagaaat ttacgatgaa tttgtagcag agttcaaatc ttaccacact tactttgtaa
    38281 acaaaaaaga aaaagctctt cttgaagagt tctgcttcgg cgtcaaagca aacagcaaaa
    38341 actgtgctgg tgcaaaattg aacgctgaca tcgttggtaa accagcaact tggattgcag
    38401 aacaagcagg atttacagtt ccagaaggaa caaacattct tgctgcagaa tgtaaagaag
    38461 ttggcgaaaa tgagccattg actcgtgaaa aattgtcacc agttattgca gttttgaaat
    38521 ctgaaagccg tgaagatggt attactaagg ctcgtcaaat ggttgaattt aacggtcttg
    38581 gacactcagc agctatccac acagctgacg aagaattgac taaagaattt ggtaaagctg
    38641 ttaaagctat tcgtgttatc tgtaactcac cttctacttt tggtggtatc ggggacgttt
    38701 acaatgcctt cttgccatca ttgacacttg gatgtggttc ttacggacgc aactcagttg
    38761 gggataacgt tagtgccatt aacctcttga atatcaaaaa agtcggaaga cggagaaata
    38821 acatgcaatg gatgaaactt ccttcaaaaa catactttga acgtgattca attcaatacc
    38881 ttcaaaaatg tcgtgacgtt gaacgtgtca tgatcgttac tgaccatgcc atggtagagc
    38941 ttggtttcct tgatcgtatc atcgaacaac tggaccttcg tcgcaataag gttgtttacc
    39001 aaatctttgc ggatgtagaa ccggatccag atatcacaac tgtaaaccgt ggtactgaga
    39061 ttatgcgtgc cttcaaacca gataccatca tcgcactcgg tggtgggtct ccaatggatg
    39121 ctgccaaagt aatgtggctc ttctacgagc aaccagaagt ggacttccgt gaccttgtcc
    39181 aaaaattcat ggatatccgt aaacgtgcct tcaagttccc attgcttggt aagaagacta
    39241 aattcatcgc gattccaact acatctggta caggatctga agtaacacca tttgccgtta
    39301 tctctgataa agcaaacaac cgtaaatacc caatcgctga ctactcattg acaccaactg
    39361 tggcaatcgt agatcctgct ttggtattga cagttccagg atttgttgct gctgatactg
    39421 gtatggacgt attgactcac gcgacagaag catacgtatc acaaatggct agtgactaca
    39481 ctgatggttt agcacttcaa gccattaaat tggtctttga aaatctcgaa agctcagtta
    39541 agaatgcaga cttccactca cgtgagaaaa tgcataacgc ttcaacaatc gctggtatgg
    39601 cctttgccaa tgccttccta ggtatttctc actcaatggc ccataagatt ggtgcgcaat
    39661 tccacacaat ccacggtcgt acaaatgcca tcttgcttcc atacgttatc cgttacaacg
    39721 gtacacgtcc agctaagaca gcaacatggc ctaagtacaa ctactaccgt gcagatgaaa
    39781 aataccaaga tatcgcacgc atgcttggac ttccagcttc tactccagaa gaaggggttg
    39841 aatcttacgc aaaagctgtt tacgaactcg gtgaacgtat tgggatccaa atgaatttta
    39901 gagaccaagg aattgacgaa aaagaatgga aagaacattc tcgtgaatta gccttcctgg
    39961 cttatgaaga ccaatgttca ccagctaacc cacgtcttcc aatggtagac catatgcaag
    40021 aaatcatcga agatgcatac tatggctaca aagaaagacc aggacgccgt aaataattgt
    40081 ttatcagtct agaagcaaga caaaaactca atttgaggga aagatccagt aatttttcta
    40141 tgataaaagg catcctatca aggtttttga acacctgata ggatgccttt ttatgatatt
    40201 gaggcctttt tgcccttttt gaaaaactag aatagaaaca aaatatataa tagattgaaa
    40261 ctagaatagt acacatctgc ttctaaaaca ttgttaga
//
LOCUS       DAVLUM010000006        37408 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLUM010000006 DAVLUM010000000
VERSION     DAVLUM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.006"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(1..770)
                     /locus_tag="VYN42_000260"
                     /pseudo
     CDS             complement(1..770)
                     /locus_tag="VYN42_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1191..1589)
                     /locus_tag="VYN42_000261"
     CDS             complement(1191..1589)
                     /locus_tag="VYN42_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461403.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(1962..2444)
                     /gene="greA"
                     /locus_tag="VYN42_000262"
     CDS             complement(1962..2444)
                     /gene="greA"
                     /locus_tag="VYN42_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1461404.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(2515..4170)
                     /gene="mltG"
                     /locus_tag="VYN42_000263"
     CDS             complement(2515..4170)
                     /gene="mltG"
                     /locus_tag="VYN42_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1461405.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(4251..4745)
                     /locus_tag="VYN42_000264"
     CDS             complement(4251..4745)
                     /locus_tag="VYN42_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461406.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(4742..5206)
                     /locus_tag="VYN42_000265"
     CDS             complement(4742..5206)
                     /locus_tag="VYN42_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461407.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(5216..6550)
                     /locus_tag="VYN42_000266"
     CDS             complement(5216..6550)
                     /locus_tag="VYN42_000266"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1461408.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(6561..7178)
                     /locus_tag="VYN42_000267"
     CDS             complement(6561..7178)
                     /locus_tag="VYN42_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1461409.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(7226..10324)
                     /locus_tag="VYN42_000268"
     CDS             complement(7226..10324)
                     /locus_tag="VYN42_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1461410.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADNHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(10417..11583)
                     /locus_tag="VYN42_000269"
     CDS             complement(10417..11583)
                     /locus_tag="VYN42_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1461411.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            complement(11591..12685)
                     /locus_tag="VYN42_000270"
     CDS             complement(11591..12685)
                     /locus_tag="VYN42_000270"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1461412.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(12843..14525)
                     /locus_tag="VYN42_000271"
     CDS             complement(12843..14525)
                     /locus_tag="VYN42_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461413.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLPPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQTLFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKE
                     WRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDT
                     EVGERGRLLSGGRSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEK
                     TVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(14697..16655)
                     /locus_tag="VYN42_000272"
     CDS             complement(14697..16655)
                     /locus_tag="VYN42_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1461414.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(16858..18480)
                     /locus_tag="VYN42_000273"
     CDS             complement(16858..18480)
                     /locus_tag="VYN42_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1461415.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18586..20031
                     /locus_tag="VYN42_000274"
     CDS             18586..20031
                     /locus_tag="VYN42_000274"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1461416.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(20077..20271)
                     /locus_tag="VYN42_000275"
     CDS             complement(20077..20271)
                     /locus_tag="VYN42_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1461417.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(20372..20980)
                     /locus_tag="VYN42_000276"
     CDS             complement(20372..20980)
                     /locus_tag="VYN42_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1461418.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            complement(21005..21517)
                     /locus_tag="VYN42_000277"
     CDS             complement(21005..21517)
                     /locus_tag="VYN42_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1461419.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAAFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(21603..22538)
                     /locus_tag="VYN42_000278"
     CDS             complement(21603..22538)
                     /locus_tag="VYN42_000278"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1461420.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(22609..22908)
                     /locus_tag="VYN42_000279"
     CDS             complement(22609..22908)
                     /locus_tag="VYN42_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1461421.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(22898..23647)
                     /locus_tag="VYN42_000280"
     CDS             complement(22898..23647)
                     /locus_tag="VYN42_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1461422.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(23701..24060)
                     /locus_tag="VYN42_000281"
     CDS             complement(23701..24060)
                     /locus_tag="VYN42_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1461423.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKTK"
     gene            complement(24062..25462)
                     /locus_tag="VYN42_000282"
     CDS             complement(24062..25462)
                     /locus_tag="VYN42_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1461424.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(25757..25996)
                     /locus_tag="VYN42_000283"
     CDS             complement(25757..25996)
                     /locus_tag="VYN42_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1461425.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(26028..26498)
                     /gene="ssbA"
                     /locus_tag="VYN42_000284"
     CDS             complement(26028..26498)
                     /gene="ssbA"
                     /locus_tag="VYN42_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1461426.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(26510..26800)
                     /locus_tag="VYN42_000285"
     CDS             complement(26510..26800)
                     /locus_tag="VYN42_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1461427.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(26953..28299)
                     /gene="asnS"
                     /locus_tag="VYN42_000286"
     CDS             complement(26953..28299)
                     /gene="asnS"
                     /locus_tag="VYN42_000286"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1461428.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGIKHIREAIPFPRMLHRIKP"
     gene            complement(28315..28680)
                     /locus_tag="VYN42_000287"
     CDS             complement(28315..28680)
                     /locus_tag="VYN42_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1461429.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLVPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEASGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(28673..29860)
                     /locus_tag="VYN42_000288"
     CDS             complement(28673..29860)
                     /locus_tag="VYN42_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1461430.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYSFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(29857..30345)
                     /locus_tag="VYN42_000289"
     CDS             complement(29857..30345)
                     /locus_tag="VYN42_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1461431.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            30666..31214
                     /locus_tag="VYN42_000290"
     CDS             30666..31214
                     /locus_tag="VYN42_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1461432.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(31452..37400)
                     /locus_tag="VYN42_000291"
     CDS             complement(31452..37400)
                     /locus_tag="VYN42_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1461433.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGVAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKENVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPRVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAQGAKGEKGDR
                     GERGLTGAQGAKGEKGAQGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKG
                     EKGAQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQ
                     RNDADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGAQG
                     PKGADGQRGPAGPQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNP
                     NQPLATITDGRNGTNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVEDGQKGAD
                     GKTPTVTITEGQNGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQ
                     GKNGDKYINTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQG
                     AKGADGAVGRDGRDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNI
                     KGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTP
                     KVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKS
                     LLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVE
                     ITVDNHDGSQPTTVFVQDGAKGKTGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDP
                     VTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGV
                     YDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGK
                     DGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKV
                     TDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDG
                     RTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDG
                     TTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETTVRDGKSPTAKVVDNGDGT
                     HTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPK
                     ANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNP
                     DGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVTKTVIKDGKDGRDGRDG
                     RDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQPTPNVPTPEVPVQ
                     PTPAVSTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQ
                     SDYISVLLGSGILLSLYVGRRKED"
BASE COUNT        10414 a         8356 c         6927 g        11711 t
ORIGIN      
        1 tgtgcataat aaatgtgctc ctcagaaaat acattagaca agcgattgaa ttccgttcca
       61 ttatctgccg tgatggaaag aatcttgtgt tgttttaaga tgagttttag agcctgattg
      121 accacctcag cacttttatt tggaatcaat cggatgatct gatgtctact ttttcgatcc
      181 gtcaagacaa gcaagcagta gtttttcgct ctcgtaagta gaaccgtatc aatctcataa
      241 tgcccattct ccaagcgaaa attgatagct tcaggccgct gttcgatgga ttgaccagca
      301 ggtttaaagt tggtgctggc ctgtttctta agcgcttttc cttttctagg gtaaagcaga
      361 tcctgcttgc tttaccccaa ttttccatga tgaatccaat agtaaatggt tgaaattccc
      421 acgttaaccc ctttagccat aaccatcatt tcaggcaaaa atttttggtt atggtagtgg
      481 agaatctttt cctttagttc cttggtcacg cttgatctct tgaccgagtg cttgcgatta
      541 ttttcataag actgttgagc atagtcggca gaataaacct ctttgaagcg cccttttcca
      601 agacattttc ggactgtcct acgcttgatt ttagtgtgga tagtttgagg agcttttcca
      661 agtagagagg caatttctct atttgatttt ccttcttttt tccatctttc gattaagcga
      721 cggctatcga ttgtcaaatg tttacctttt gtagtataat tgtcttgcat ttctgtgcct
      781 ttcttgtgtt tgtggttgaa caacaagtat aacacaaagg tgttttctta tgcctacaag
      841 agctttcatt atttccattt tcttttggat ttcactctat tctgaaaaac ttgtgtatat
      901 ttactgaagc tagcaagtct tacctgtaaa tttaatgaaa gcaacacaaa atccgagagg
      961 ggaatctcgg attaatgtca atttaaaaag atagagagtt tttagtttaa ataaattgtt
     1021 ttaaaatatc aacaacatca cttcttttct taacctgata agccttgatt cctaattttg
     1081 gggctacgat tatattgtcc tcaatatcgt ctagaaagac acaatttcta ggttataact
     1141 ggtatttatc gatagttact catatatatc agtccacctc catactcacc ttacagattc
     1201 ttttgataat aatatctttg cctaatgtag agatagtctt gcaaagaaaa aacttccttg
     1261 tagccatgtt tctgataaaa gtccggtgcc tggaactggt aagtattgac aaaggcaaaa
     1321 caacaatttc gattcttagc ttcactttct gcctgttgca atagttttga accgattcct
     1381 tgccctcgca gttcctcttt tacaaacaaa tactcgattt ctagccaatt tccaaaagtc
     1441 tctgctatca aacccgcaag gagattgccc ttttcatctt cgacataaag attaagtggc
     1501 tcactttcag cctcttctct ttttgaacgg ttataaacac gaatcagatt ccctatttct
     1561 tgcgatttat gtgattcctt attttccaat ctaaagtata atgaaatgaa ataaaacatg
     1621 cgcaaatcga ttaaggaatt taatctaatt tctaacaatg tcttagaaat caaagtgtac
     1681 tattttaact tcaatgcact atacatctaa tactcaataa aaatcaaaga gcaaactagg
     1741 aaactaggcg caggctgctc aaaacaccgt tttgaggttg tagatgaaac tgacgaagtc
     1801 agctcaaaac atggttttga ggttgtagat gaaactgaca aagtcagtaa ccatatatac
     1861 ggcaaggcga cgctgacgtg gtttgaagag attttcgaag aatagcaaaa tggaaaaagg
     1921 agtgagtgaa gcacatcgcc tccccactcc tttttctgtt tttaggctgt tttttcaacc
     1981 ttcaagattt ttacatcata gctaccaaca ggcgtttcaa tggttgctgt gtcacctgtt
     2041 ttcttgccaa tcaaggcctg cccaattggg ctttcatttg aaaccttacc tgcaaaggca
     2101 tccgcaccag ctgaacctac gataatataa acttcttctt cgtcctcacc aatttcttgg
     2161 atggtgactg ttttaccaat cgctacttcg tcctgggcaa ctgcgtcgct attgacgatt
     2221 tcagcatagc ggatttttgt ttctaagcta gagatttgtc cttcgacaaa ggcttgttca
     2281 tccttagctg cttcgtactc actgttttct gaaagatcac cgtatgaacg ggcaatctta
     2341 atgcgttcta ccacttctgg tcgacgaacc aatttcaatt cttctaattc tttttcaagt
     2401 ttctcctttt cctcaagggt cataggatat gttttttctg ccatttttct caactttctt
     2461 ctgataatat tttctaaaga aaattatgtg aagtatcaca taattttagt ttgtttagtt
     2521 taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg tcttcttgat tgttagcata
     2581 gtagaccttg ccttctgtga catctgctac aaagtagagg ttatcgctct tagtttgatt
     2641 gatgcttgac tcaatcgcat ccagacttgg actatcgact ggaccaggca tgagacctac
     2701 atttttataa acattataag gtgaatcaat gtcggtatca atcgcaacat cctcagctag
     2761 actgatattt tgccccagtt ttccttgggc atacaagatt gcaatattac tttgaagtgg
     2821 catatcacga tttaaacgat tgtagaatac acctgcaatg agcttacgat cttctgtctt
     2881 ggcaccttct ttttcgacca aggaagcaat ggtcaacaac tcattgatag tcaagttttt
     2941 agatttgata gtactatagt aaggagatag gttcttatcc atagcagcta acatctcatc
     3001 aatcaagctc tcaatagttg tgctttcctt gatagagtat gtagctggga aaaggtatcc
     3061 ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa ctttccagta aagtaggata
     3121 tttcgctact gcttgactga taaacgtctc atcttgaact ttagccaaga aagcctccgc
     3181 tgtcaaagac tctttgaagt caccttgcaa ttgacccaca gtttgagcaa tctgatccaa
     3241 ggtataacct tctggaattg tcaaagtcgc aagtacaggt tcttgcggtt catctgttcc
     3301 acctttttgc aactctttga gtaagtcttc tgtactcata ctcttttgca aattgtagta
     3361 acctgctttc aagtcggtat aatttttata cttggcataa aaactaaaaa tcagaccatg
     3421 ctttaccaaa ccagcttttt caagcgtcgt accgatttct tgaacgtttg aaccttctgg
     3481 aattccaacc gtcacatatt tcttagaatt agcatcgata ggtaacaaag aatctagcac
     3541 gtactggtaa ccaaagtaac cacctgctga gagcaaggca aggaatacaa ggaatgaaat
     3601 cacaaaagct ttcacatgtg acttcttctc tttcttaggt ttaacgggtt ttgctccttc
     3661 tctacggcta cgacgtgatg tatcgctgat gatatccact gtttctgtag caggcgtagg
     3721 tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc gtataggaaa cagctaccct
     3781 tgttggggtt tcattgtatt ctctttcaag tttcttaggt ctaacaggac ctggacctgg
     3841 tcttgatcca ctttcttccg ctggagaaga aggtacatct tgacttggat gacttggaac
     3901 accaggagtt tctctttgaa tctcatctgc tggagaagct ggtacacctt gacttgggtg
     3961 agtaggcacg gtaggagctt ttctcataat ctcctctacc gttgacaagg aatcagccat
     4021 gagttcttca gctgaaggtt catttgcagg agtgcgaact actgcctcat cttctttcag
     4081 aacttcatca tagcctttta ctttttctaa atctctcaga atctgctctt taaagcttaa
     4141 tttctcttct tctcttgact tttcactcaa aagtttttcc tccttgttga taatccataa
     4201 tattatatct taaaagtcca aaaaaagcaa tctatgatac ttttcctaac ttattttttc
     4261 atttcccaga ccatatcata ccatgtttcc cctgcaaagg ttgactggga ctggccttcg
     4321 ttgacaaatc catgtttttc atagtaggcg atgagatagt catgacaggt tagattaatg
     4381 ccatctctct catcttcaag agcaacttct ttcaaggctg tcagcaattt ctgacccagt
     4441 ccgagtccct gtgcctcctt ggcaatagac agacaggtca cagagatata accaccaggc
     4501 tcatgactat agtcttttat ttcttctgta aaagactggt cttgcagatg gcggtgcagg
     4561 ccaactggtc cttcgatata acccatgatt cttccttctt tttcagcaac cagaaaagag
     4621 gtctgaattt ctctcaaatg tgcttcaaag acagaaggag gaatggcttc ttcgaccgaa
     4681 aaattttcaa attcaagttc aacaatccga tccaaatctt ctaatcttgc ttgtctgatt
     4741 ttcattgttc ctccagataa aagggattaa accaaatcat actatagccc tggctagttg
     4801 catagagcaa agtttcttct tcatcaacaa aaccgttcat ttcaaaatag gaaagcagct
     4861 catcaggact ctccaaacga atccctttgc aatccagctc aactgccacc tctttcaagg
     4921 ctgcaagaag aagtgttccc aggccctgtc tctgatggtc agactcgatg actaaagaat
     4981 gtacttttag acattgcgga ttgtctgact ggggacttga taaaatatag cctaaaagtt
     5041 gattttcatc cctagctaga agaaaggtat ccgcacactt acggatactt tcttctaaaa
     5101 tatgggaaag ttgctgcttt tcagctggaa aagacgaggt ctgaagtgcc cctatctcag
     5161 gcaaatcaga cttgcttgcc tgaatgatct taattggaat ttccatggga acatcctatt
     5221 gaacattgct tgtcaagtta gataagagac gctcaaatga gtattcatag gtttggatgt
     5281 ctcctgctcc cataaagacg taaacagcat tgtcatggtc taggagtgga gaaacatttt
     5341 caacagtaat cacttggtgt tttttgttga ttttgttggc taggtcttct accttaacgt
     5401 caccatgatc tacttcacga gccgagccat aaatttgcgc tagataaaca gcatctgctt
     5461 ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt tcttgtaaag gtatgcggtt
     5521 gaaagactgc tacaatttcc ttgcttgggt atttctgacg agccgcatcc aaggtcgcaa
     5581 taatttctgt tggatgatgg gcaaagtcat cgataatcac tgtatcattg acaattttct
     5641 cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg ctcacgcacc aagttcaaat
     5701 caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc attcatgata ttgtgacgac
     5761 caaaggttgg aatgtggaat tgccccaagt tttgtccacg gaaatgaacg gtgaaggttg
     5821 aaccagttgt tgaacgaaga agatcactag ctacaaagtc attgccttca gcttcaaaac
     5881 cataataata aattggtgca tcagacgtaa tcttacgcaa ttcagcatct tcaccataga
     5941 caaaaagacc cttggtaatt tgtttggcat agtcgttaaa ggcattgaaa acatcctcga
     6001 gacttgtgaa ataatctgga tggtcaaagt caatgttggt gataatagag tattctgggt
     6061 ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa gacaaaatat ttggcattag
     6121 ccgaaccacg acctgtccca tctccaatca agaagctggt atctgtaatg tgagacaaga
     6181 catgagacaa catacctgtc gttgaagttt ttccatgtgc tcctgctact cccatgctaa
     6241 caaagtcacg cataaagcta cctagaaact catggtaacg tttgtagctg ataccatttt
     6301 ggtccgcata ggcaatttcg acgttgttat ctggacgaaa ggcatttcca gcgataattt
     6361 ccatatcacc gtctagattc ttttcatcaa aaggaagaat ggtaattcct gcctgctcaa
     6421 gaccgcgttg ggtaaagtag tacttttcaa catctgatcc ctgaaccttg tgccccatct
     6481 ggtgcaacat caaggccaag gcactcatcc ctgatccctt aattccgata aaatgatatg
     6541 tctttgacat gttttctccc ctattctgtc attctggtca gattcaactc ttgggcaacc
     6601 cgacgttctt gttctgtttg tttacttttt ttattgtaga tttggctctt ctttagaaaa
     6661 tcataattgt ttttctttgg agcaggtgct gacacttctt cattcttggt agggatagaa
     6721 tgaacttctt ccgccaagat ataatgagac tgggtcaatt tttggctata tttgacaaat
     6781 tcaccaggat tttccttttg gaaaggagtt gtcggttgat tgccctgtct aactagactg
     6841 ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta ggtagttagc agagcgtttc
     6901 tttttcaagt ccgcacgcgc ttcttcacgc gccacctccg catagctctt tccttctttt
     6961 ttaaccccta aaggagcctt tttaggtttt tcgacttgct tttcaatcgg ttttactggt
     7021 ttttcttcag taataggagc ccattctaaa taatttttat ctcgatactc acccttgata
     7081 ttactgatca gatcagactc atcatagaga ttcatgactg gcatttcagt caacatgacc
     7141 tcgtcatctg acaccaatgg aaatcgttct tgtttcattt tctatttcct ttcaacactt
     7201 cattatagcg tattgtcttg atttttcaag tgctggcttc agaaattccc aaaatttctc
     7261 taatttctgc tagggtcaga ctaccacgtg actctgtgcc atccaatact tgtgacacca
     7321 gatgtttctt ttgttcttgg agttcctgaa ttttttcttc aatggttccc ttggtcacca
     7381 agcgatagac ctcaaccgtt tcttcctgac ccatccgatg ggcacggcca atggcttgcg
     7441 cttccaccgc aggattccac caaaggtcaa ccaagatcac tgtatctgca cctgtcaggt
     7501 tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc atctctttct ccttggttaa
     7561 aggccttggt catgtcttgt ctttccttgg ctggggttga acccgtaatt ttaaaggatg
     7621 tcaggcccaa gtctggcagt tcttgttcaa ttttttccaa cattcccttg aactgagaga
     7681 aaatcaagac acggtgtccg ccgtctgcca cctgtaccag taggtctcgg agactatcta
     7741 gtttgccgct ggctccctga taatcttcca taaacagggc aggagtgtca catatttgac
     7801 gcaagcgcat caaaccagat aaaatttcca cacgacttcg ctgaaattcc tgttctgaca
     7861 cttgagccag atggtctcgc atctgttgta actgggcaag gtaaatagcc ttttgctggt
     7921 cttccagttc atttttataa accacctcaa tcaagtctgg caattcagtc agaacttctt
     7981 ctttcttgcg tcgcatcacg aaaggcttga taaactgagc cactcgctct gctggcaatt
     8041 tcataaattc tttcttgctt ggcaaaagtc cgggcatgac gatttggaaa atagaccaca
     8101 actcacccag atggttttca atcggagttc ctgacaaggc aaagaccgac ggcaccacaa
     8161 attgtctcaa ggtctgggca atcttggtct gggcattttt catgacctga gcttcatcta
     8221 agaaaaggaa gtcaaaggcc atcccctgat aaagctcact gtcctgacgg aaggtggcat
     8281 agctagtcac atagatttga tggttatcgg caagaatctc ctcacgactt gctttcaaac
     8341 catgaacaac agccacatcc aactgtggag caaatttctg aaactcatcc gcccagttgt
     8401 aaatcaaacc cgacggagcg agaatcaaga ctcgactttc ttttgtcact tgactagtca
     8461 aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc atcagccaaa atcccaccaa
     8521 aaccataatg atggagcatc tgcaaccagc caattccctt ttcctgataa tctcgcaagt
     8581 cagccttgac ctgagttgct tgcaaaggaa agtcctctgg atgtgtcaaa tcctgggcca
     8641 gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc ttcaaagaga tgagctaaac
     8701 tgtaggctaa ggatttccga gcctgcaagg tcccatcttt taattcaaat tgccccagtt
     8761 cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa aaagtaaact tgattagacg
     8821 aatcaatata aaaatcctga ttggcaacca aggcctgtat ggcttggtcg atttcctcct
     8881 gggcaatatc ttgaaaatca aactggattt ccaagagacc tcccttggag gcaatctgca
     8941 cctgaggact cgctaggcta taaagctctt ctagtttatc tgataggtca acatgcccga
     9001 gtttttcaaa gactggaatg atatcatgaa aaaaatgata gacagactcc gcttttaagg
     9061 cctgacgcca agattgaaaa tcggcttcaa agcccgcagc caaacagact tggaaaattc
     9121 tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc tagctcttgt cggctagata
     9181 cctgtctatt tccataatca aactgaattt ctaaacgaat ccgattatct tcttccctgt
     9241 caaagtaaaa agagggcgca aaagttttga tttgtagacg ttctggagct gaaacggtgc
     9301 ccatctggat aaaaagagtc agacaggagg ccaatttgtc tcgatcactg ctatcaaatt
     9361 gcaggtattt ctttccttgt cgatccacag gtaacgcttt aatttccttg agaagacgca
     9421 tctgctggtc tgttaaaaaa taaacctgac ctttatggaa aagtactgct ccttgataaa
     9481 agacattgac cctaggactc tcactgattt ccatttcaaa atagtccgaa tattctgtta
     9541 ctgtaaaggc aaatagattg gcatcagcat gcatatcctg aaaaagcagg gtttggtagc
     9601 tatccacttg atggtcaaat tgaaaatggg gcaaggccat cagtaaattc acaccctgct
     9661 caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt ttggaaaaag aggtctggaa
     9721 ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag ttcttggctg gcatcatcaa
     9781 aggcttccca agaaagagac tcctcataaa tcttgccaat catatacgac tttctctgct
     9841 cgacaatcct taaaaaaagt ggaatatccc gaatgacata gtatttttgg ctattgattt
     9901 ggccgattct cagagtccac aagatatgat tggttcctgc ttccacctga cccacagctg
     9961 ataactcata ggcgcattct gattttggag ataaaattcg atccaaaaac ttgccaccca
    10021 aggtcacctt ggtttcaacg gcctcttttt cttcatgacc ttcttccaga ctccacaaga
    10081 tttcctgacc acgctcatca tttttcagaa aatgctctag cgctgccaaa tgcacacagt
    10141 agcccctctt ttgaaaaaaa tcacaggcac aaaaaatcaa atcatcctct aaactatagc
    10201 gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt cttttccttg atgatatcaa
    10261 ccttaccagt ttcataaagg gcaacacctt cgatacgaat tttccccgga atcaatttag
    10321 ccatattttc acctttacct tatcttttta ttataccata ttttcgccta tgaaaatagc
    10381 cttctaggaa gacttttctc ctagaaggct ggatttttaa catttggcaa aagtagccac
    10441 aatccgctga cagacttctt gcaacagaga tttgggcata gctatattga tgcgggcatg
    10501 gagacttcct tcctctccaa aatccaaacc acggttgagg ataaccttgg cttcatttct
    10561 caacaactct tgcaatgttt catcagtcag gtcataagct gaaaagtcaa gccaaatcaa
    10621 gtaggtacct tgcggtttca tgaccttgat tttagtctct tttccaaata gatccaccac
    10681 ataattgatg tggtcttcaa agacttgctt gagttcctct agccaatctt taccgtatcg
    10741 ataggcagct tctgtcgcca aataacccaa gcctgaaatt tcatgctgat tattggccaa
    10801 caggcgtttc tggaaagcca gtctcaactt aggattttca atgactgcat aggaattttt
    10861 tgttccagca atattaaatg ttttagtggc actgctcaag acgatagcaa aatttttgaa
    10921 ggcaggattg atggtattga aagactggtg tttgtgacca aagagggtca aatcttggtg
    10981 aatctcatcc gaaactaaca aaacaccgtg tttttggcag agttggccaa tcttctccaa
    11041 cacttctttt tcccaaacac gtccaccagg attgtgaggg ttgcaaagaa catagagttt
    11101 aacctcctct tccaccaaat ccttttcaag ttggtcaaag tcaatctcaa acagactatc
    11161 cttttccact aaggaattag taatcaatct acgattattc aacttgacac tgcgagcaaa
    11221 gggtgggtag acaggcgtgt taattaaaac cgcctcgcct tcttttgtaa aggtttgaat
    11281 agctgttgag atggctggta ccacaccctc gataaagaca agagcctctt tgtcaaagtt
    11341 gtaaccgtat tgtgtagctt cccacttttg aacttcctta attaagtctt cactggcata
    11401 ggtataacca taaaccagtt ggtctgcgta agtttgcacg gcttggtgga tttcaggcaa
    11461 gactacaaag tccatatccg ctatccaagc tggtagaact tcactatccg tttctgtttc
    11521 tttccattta taggtatggt gccctaaacg gttgggcagg cttgtaaaat catattttcc
    11581 catctttgtc ttatccttct aaggcttggc gcaaatctgc aatcaaatct ctagcatcct
    11641 caatcccaat agacaaacgc aagaggtcat ctgtcaaacc ataagaatgg cgtacttctg
    11701 ctggaatatc agcatgagtt tgagtcgttg gataagtaat aagactttcc actccaccca
    11761 aactttccgc aaaagagaag accttgagac tgttcaaaat atgaggaatg cgtgtttcat
    11821 cggctacttt aaaggaaatc atgcctccac gaccagtgta gagaacttcc ttaactgctg
    11881 gagaatcctt caaaaaggca accacttctt gggcgttagc tgttgagcgc tccatacgaa
    11941 gagacaaggt cttgagacca cgaagcaact ggtagctgtc aaatggagac aagactgccc
    12001 ctgttgtatt aagattgtaa aaaagcttct cgtatagttc taaactattg gtcacaacca
    12061 ctccagccaa gacatcattg tggcctgcta gatacttggt tgctgaatgg agaacgatat
    12121 ctgctccatc ttcaatcgga cgttggtaga tagggctata gaaggtattg tccaccacca
    12181 ctttggcacc cttagcatga gccaattttg ctagtttttc gatatcaaat tccaacatca
    12241 agggattggt tggggtttcg atatagagaa catccacatc cttttctaac tcggcaatca
    12301 actcttcttc tgtattggca taggtaaaat ggaaatgacc ttcctgctcc acttggttaa
    12361 accagcgaaa agaaccaccg taaagatcac gcactgccaa gaccttactt cctactggaa
    12421 agacgctaaa ggccagtaca atagctgaca tccctgagct agtcgctagg gcatagtctg
    12481 ctgactcaat agccgccaag acttcctcag ccttactacg agttggattt ttagtgcgcg
    12541 tatagtcaaa cccagtagat cgaccaaact ctggatgctg ataggtcgtt gaaaaatgaa
    12601 gtggtgtcac caaagcacct gttgcctcat cagacttgat ccctgcttgt gctaaaattg
    12661 tgttaatgtg taattccttg ctcatacaat tcctccaaat ctatagtaac tattgtacca
    12721 cttattttca tcaactcatt ttcttctttt caagagctag ttatagtttc aaactatata
    12781 aaaagggagt ttttcctgct ccctttaata gactataaaa tggtgaatct caaaagacac
    12841 cttcactcta tcatttgctc ctgcacaaaa cgagcataac gctcatgatt ttccagtagt
    12901 tccttatgag ttcctgagcc agtgattttc ccctcctcta agaagaaaat acaatccaca
    12961 tcttttaccg ttgacaaacg atgcgctata atcacaaccg tcttctcctt tagtacagaa
    13021 tagaggctac tgataatcgc atactcagaa tccgcatcaa gattagcagt ggcttcatca
    13081 aatataagaa tttcagcatc ttttaagtag gctctagcta tttgaagtct ttggcttcgc
    13141 ccccctgaca agagtcgtcc gcgttcacca acttcagtat ctagtccctc tttcatggag
    13201 cgaatctcat cacctagtga tactaagtct agcactttca tcaattcatc atcagttact
    13261 aagcgattca aaccgagaca aagattgtca cgaatactgc cagataagac tgcattattt
    13321 tgtgaaaccc aagcgatttt acttctccat tcttttaagt taaaatcata tatacttgat
    13381 tgctccatta gaatatctcc tgaaagcggt ttataaaacc gctctaacaa acgcacaatc
    13441 gttgattttc ctgatccaga tggcccaaca aaagcaattt tttgcccctt gaaaattgaa
    13501 caagtaatat cctttaagac aggtcgattt tcatcataac caaaatagac atggttaaaa
    13561 ttcaaccctt gtcctgatac cgattttcct ccctcaaatt tttctttagg aactgcaagc
    13621 aagttctcca gtgcaactga agatcccttg ctactagaat aaatagttac aaaattagct
    13681 atattactaa taggattaag taattgaaag aggtaaatca aaaacgaaac caaggttccc
    13741 acagatatat atcctgcgct gacccgataa cccccatagg ttagcatcac aactatagtc
    13801 gcaaagataa ataagagagc aaacggggtc tcaaaagaag taaccctatc tgatttcagt
    13861 gaattgtttt gtaccctttc aatacaatta tccaaaacat cctgtacact tttctctgct
    13921 tggttagtct taattaattc atgttcttga atcttttcag tcaattgccc tgttaaaaat
    13981 ccgatttcct cctgtaaacg acgactatac ttttcactga tattggaaag gggcaagata
    14041 ataaacatca tacaaggaag agtgatgaat aaaagtagag aaagattcca atcaagacta
    14101 aataagacta caatggaacc aagtaccata actaaactca gaataatatt tgggaaagtc
    14161 gtaattaaaa actcacgaat gacactcgtg tcattgacaa tggcagaagt caactcccca
    14221 ctttggctct tatcaaagaa ggatttctct gcataaatca acccctctat cacttttttc
    14281 ctgatttttg ctatcttttt ttcacccgat tgactaaaca gatagtaacc aatagaagaa
    14341 aacaaggttt gaccaataaa aatcaaaaac gattgaaata ctttggaacc tatattttca
    14401 atagaactcc catctattaa accttttaag ataaggggag gcaacaaagc aagtagacta
    14461 gacagaacaa ggaagaaact ccccataatc accttagtat ctactcttaa taattttaat
    14521 ttcataaata ctccttataa tatttcaacg gataaagtcg ggaataactc aatttgagga
    14581 taaaatctaa taaatcttcc tataacaaaa cgcataacat ctaggatttt atatacctga
    14641 tattatgcgt ttttaagcac aaagacttct tacacaaact tatctacaat tagattttat
    14701 ttgacatgtt ttgccaattc ttcttgggct tttttattgg attcttcttt ttctttcaac
    14761 catttttctc tggcttttgc atattcgtct gttgtgacaa tcttatcttg tactttgagg
    14821 tatttatatg attcaacccc ttttgtaccg gttaaaccat aggcagcagc aaatggtacg
    14881 gttcttctca atgatggtgt tcccccacgc gaaacacttg gaagaactaa agaactatca
    14941 atcaaccaag cttgaatatc agcatatttc tcataacgtt tggctggatc ttgctcttta
    15001 ttagcttctt ccaacatttg agtatagaca tccagtccaa cttccttagc cttgtcattg
    15061 gcttctccag gctctagtcc aagattttgt agaactcctc cactattagt attaaaaata
    15121 tcgagatagg ttgacgggtc ttgataatca ggtccccaac cgccatgata taaatcatag
    15181 tctttctgag cagctgtttg agcaaagtag cctgaactgt caaactcatc tgatgttaat
    15241 tgctgaatgt caatcactac attatcagaa cctaaaacag attcaattga ttgtttgata
    15301 gaactaactc cttgtatgcc tactttatct gttacttcca cagtcttatc caagtggatt
    15361 gggaattgaa caccctttgc ttcgagttct ttcttagctt ccgcaaactt agccttggct
    15421 ttctcaggat tgtagtaagg gtcttgacca tccgcaaagt tgataccttg ccattcctta
    15481 ccatagttga ccatcttaga ggctacaact tcaccaaagt cttttccctt gatactgaca
    15541 aagtttggag gaaccactag gttacgcaaa atctttgttg caccttcttt cccttcagac
    15601 tgagccccat aagatgttct gtcaaaagca aaattgatag cctgacggaa gtttttattg
    15661 agaactgctt cctgagtcga tttcttttca atgtcacttg ttttagaagt ataattgtaa
    15721 gacttcctat ctaggttaaa attaaagaaa tatgaagttg aattttgcat actatagatg
    15781 atattgtttt tgtatttttc tttaatccct tcatagctgg agctgttagg aaaaagacga
    15841 gccgtagtat aagcaccagc tgtaaaatta cgttccagtg attcttggtc gctaccatca
    15901 tagtaggtca atttcacatc gtctacaaag acattcttag catcccagta attagggttt
    15961 ttcttatatt caatagcaga ttttgagaca agtgctttca tcaagaaagg tccattgtac
    16021 aaaatactag atggatccgc cttcccaaaa tcatcccctt ttgatttcag gaaatctgca
    16081 ttaacaggaa aaagtatcgt tgcaagtgtt tttgaattcc agtaaagttc tggtttaacc
    16141 aaagtatatt gaaccgtttg gtcatcaagt gccttgacac cgacagttga aaagtcgctt
    16201 gttttaccag tgatatagtc atccaaacca gcaacagagt cctgcactag atacaaggct
    16261 tctgattttt tatcagctgc atattgcaaa cctgtcacaa aatcctgggc agttacaggc
    16321 gcatattctt ctccctcaga agtaaaccac ttggcatcct tacgaagttt gtaggtatag
    16381 gtcaaaccgt cctgagaaac agtccaatcc tctgctaatg atggaataat attcccatat
    16441 tggtcatttt ctaataaccc gtctaccaaa tttgcaacaa tatcggatgt tgctgcgcgg
    16501 ttttctgcta gatagttcaa gctagatgga tcacttgaat aaacatagtt gtaggttttt
    16561 gacgccgtgc tagaatttcc acacgcgctc aataaaactc ctgtacccag gacaagacct
    16621 gccaaggtta gatatttgct cttagacttt ttcatttccg gaacctcctg ctttaaatat
    16681 ttgttttatt atacaactct tggtttgttt agtcaattgt tttttccaaa aaatcaaaaa
    16741 aacctcattt tctatttttg aaagataatt ttagctattt ttacgctaaa aaaggaataa
    16801 gtttcaagtt ctcctaaaag attgttcaac ttattccttt tatttataaa tgctacctta
    16861 cgaaagctta aattttgctc gcaggcgatc tgcttgggct tttcctatta ccttatctaa
    16921 caaataggta cgcagactca taaccatata aagtccaccc cccatggcac cgacaagagc
    16981 tacataaaag aagctccaca aacgtccact tggttggaag aaaaatccta acagccactg
    17041 gatggttcct attaacagaa acatgactag ggtcagcaaa ctgattaaaa tggttcgctt
    17101 caaaatcacc ttgcgcttga caccagttac tttacaaata tcccgataca tcaagacgtt
    17161 aggaatgatg agagcaatgg ttgttgaaat caaaggacca taactgtgga agagggcgat
    17221 ggtaggtagt tgcaagacta gcttggcaat agaaccatag ataaaataga gaacggcctt
    17281 tcggttgcgg aacatggcct gaagcattgg agacaagacc atgtacaagc ctaaaataat
    17341 agactgcaaa actgcaaaga caaataagcc cagagccaaa ctatctggct taccatagaa
    17401 gaccgtataa agaggttctc ctaccataac cactccaacc gttgctggta gcaagaacat
    17461 aaagagtagg gtgagactgt cctgaacgag acgagaagct gctttcaagt cccccttgac
    17521 atagttttcc gtcaaaagtg gcaaaccaac actcccaatc gaaaccccta cagaaatcaa
    17581 aatcatcgtg attttattag gattggctga gaaataagaa aacatgacaa ccaagtcctc
    17641 attgctgtag ttggtaaacc agctcatact attgataaag gtcagctgat ccaaaatctg
    17701 gaagagctgg atggcagacc ctgtcaggat aaaaggaatg gcttccttaa tggtatcaac
    17761 caagagacgc ttactgttaa tcttatctcc tgtttcaaag actcttttga gtgaaccttc
    17821 ttgggcaagg aaataaatca agactgcaaa actggctacc ataccgacaa aggcagcaaa
    17881 ggttgattgg gtaacggctg ctagataatc tcctgaaccg agcttcataa tgataaaggt
    17941 tgctaggagc atccagataa cacgaatgac ctgctcagca atttggctca tggcataggg
    18001 tttgaggtta ttcatccctt ggaaaaatcc tcggataaca ctcatagacg ggaaaatcaa
    18061 gactccccaa gccaagcttt gcatgattgg gatcaagtct ttgcccacgc cagacaagtc
    18121 tgctagccaa ggagcaaaga catacaagac taaagcaaaa accaggccta gtcctgtcat
    18181 aaagcctaag aagctccgaa tcagggcaaa gctatgctct tcttctcgca tggtattata
    18241 cttggcaact tgcttggcca ccgcaactgg aatccccgct gttgaaacca acaagaacca
    18301 agcatagata ttgtaaccca tggtaaagag accatttgcc ttagctgcat aagcccccat
    18361 ccagatgtac caagggataa tgtaaacagc cccgagtagg cgactgataa agttactagc
    18421 cgttagccaa gcagtccccc gtaacatctg ggcctgctgg tgattgtttt cgtgcgacat
    18481 agattcctca ttcaattttg atagctagga aaaactcctt atcttccatt ataaactttt
    18541 ccttgttact tgtaaattta cgactttcgg tttacaatag aaagtatgat taagattgaa
    18601 accgtattag atattttaaa gaaagatggc ctttttcgcg aaattattga ccaaggtcat
    18661 taccactaca actacagcaa agttattttt gatagcatca gctacgacag ccgaaaagta
    18721 acagaagaca ctcttttttt tgcaaaaggc gctgccttta aaaaagaata ccttctttct
    18781 gctataacac aaggcttagc ttggtatata gctgaaaagg actacgaagt cggtatccct
    18841 gtcatcattg tgaacgatat aaagaaagcc atgagtttga ttgccatgga gttctatggt
    18901 aatccacagg aaaaactcaa actccttgcc tttactggta ctaagggtaa gacaacagca
    18961 gcctatttcg cctataacat cttatctcaa gggcatcgac ctgctatgtt gtcgaccatg
    19021 aacacaactc ttgatggaga gactttcttt aagtcagcgt tgacaacccc tgagagtatt
    19081 gacctctttg acatgatgaa tcaggctgtg caaaatgacc gtacccacct catcatggaa
    19141 gtctccagtc aagcctatct ggtcaaacgt gtctatggtc taacctttga tgtgggagtt
    19201 ttcctaaata tcagcctaga ccatatcggc ccgattgaac accctagctt tgaagactat
    19261 ttctaccaca agcgtctctt gatggaaaat agccgagcag tcatcattaa cagtgacatg
    19321 gaccacttct cagtcttgaa agaacaggtt gaagatcaag accatgattt ctatggtagc
    19381 caatttgata accaaatcga gaattccaaa gcctttagat tttcagctac gggtaaactc
    19441 gctggagatt atgatatcca actcattggc aacttcaacc aagaaaatgc agttgctgct
    19501 ggacttgctt gtctccgtct cggagcaagt cttgaggaca tcaaaaaagg catcgctgca
    19561 acccgcgttc ctggtcgtat ggaagtcctc actcagaaaa atggagccaa ggtcttcatc
    19621 gactatgccc acaatgggga tagtctgaaa aaactcatca atgtggttga aactcatcaa
    19681 accggaaaga ttgctctggt tctgggatca acaggaaaca agggagaaag tcgtcgtaag
    19741 gactttggcc tcctcctcaa tcaacaccct gagattcaag tctttctgac tgctgatgac
    19801 cctaactatg aagacccaat ggccattgca gatgaaatta gtagctacat caatcatcct
    19861 gttgagaaga ttgcggatcg ccaagaagcc atcaaggcgg caatggctat cacaaatcac
    19921 gaattagatg cagttattat tgcgggtaag ggagccgatt gttaccaaat catccagggc
    19981 aagaaagaat cctacccagg agatacagcc gtcgcagaaa attatttata agaatagaaa
    20041 aaatcaaggg aaaatgaaac ccttgatttt ttcctattat ttagtaaaaa cgtttttcaa
    20101 accttcaacg gcaccttcta cagcaccttt tgcgtcttct acaacgtctt ttgccttagc
    20161 aactgttttt tcaacagctc cttcaagttc tgtcttgctg tctccagtaa ctttaccaaa
    20221 accttctttg acagcgcctg ttgcttgttc caatttgttt tcaagtgaca tatgattgtc
    20281 tcctttagtt tattccgata tgtgttaccg gttacatata gtttataccg aatactaagg
    20341 aaagtcaaac aatgtactca gaaacaagaa atcacgctaa gtagaaagtt aatctctcct
    20401 tatcaaaatc gatagccaac tcatactttc catcttcatt ttgcacaata tagcctaaga
    20461 caaccaaact gtccacaaag atatcacggc atttctgcat aagctggtct tttttgagaa
    20521 atttcaacaa aaaagccgtc atatacttga gtgcatactc aggattaaca tctcctaaaa
    20581 tgtcatagag ctcctgctgt ttttctgtca aaggatactg ctgtttgacc ttgtaaaaat
    20641 aattggacag ggtcatttta atgcgcgcaa agtccgtctt ttcaactaaa atagctgcat
    20701 tgatttgatt gcgcaattcc gtctcaaaac tctgctccaa caaggcttga tagaccggac
    20761 tagcttctct gacaaaaatc tcttgatcca gttcaagact atcaagtgat tcaagcgtag
    20821 gaaaattgag gtaatagcgc ttattttcac gtagaatcaa gcctgccttt atatactctt
    20881 ccatgagttt atcaactgca acatctggaa attgagcctt aatttcccgt agaatcacat
    20941 cctcatactg gtccagatag cggatcaatt ctccaaaaat ggctgtctcg tcaaacgaga
    21001 tggattaaaa atctgaatca tgaagattcc tttctttaca ttgtaacaga ggcgatgctg
    21061 ccaactgact aggattggta ccagcttggt tcagaggaac aggcagacct agttctatgt
    21121 aatactccct ccaaaaatca ctaatctcct gctccccatc tccaaatttc ataggaatag
    21181 tttcaaaaat aggtaggatt tctgctatat actgggagca gtagaaagca gctgcatctg
    21241 gatagaaaga agcattgtag ggtgctccaa gatgtctgca agctctttcc ttcaccgact
    21301 ggatatccat ttctgggtaa acatagaggt cgtataaatg attggactca aagaagtctg
    21361 ccggttcttg acagacaaca ccagcctgtc cactagcatg ataaatcatc ccatccaaat
    21421 aaatggcaac atggctatag ttacctgtgg aagtctggat ggcctgtccc atgtctgacc
    21481 catctctcac aaaaatcaaa tcgccatttt ctaacatact tcactcctag aaaaaaggag
    21541 ccgaaactcc tttcgatata aggcaaacta gactttccga ttttgagctg acacccaaaa
    21601 tcttacgcat taaagctttc agtcaattga ggtaccactt gtttcttacg tgaaacggca
    21661 ccagcaagga aggcatgatt gttttcaagt ttgaagttga aagccgcttc gaccttgtcc
    21721 atattggcac caagagccaa gatttctgag tttgagttga cgatatctgt aatcatcaag
    21781 acaaagtcag agtagccgtt tgattcgttg gcagcttgca ttgcagcttc aatttctgct
    21841 tggcgttcca aaacttcagc gatgtcaact gtgttcactt gggcaacacg gacattattt
    21901 ccgttgagtt caaaagtctt agcatcgata tcaatcaatt cttcagcaga tttgctagcc
    21961 aagttggtac cagctttcaa cattgccaaa ccatattctt ccaagttcac accagccaat
    22021 tcagccaatt caggagcaat gattttatct gttgggtgtg ttgttggtga tttcaaaaga
    22081 agggtatctg aaatcaaacc tgaaagcatc aaacctgcaa tctctttagg cacagctaca
    22141 ccatgttctt tgaacatacg gtaaacgatt gaagacgctg atccaactgg ctccaaacgc
    22201 atgtaaagtg ggcttgcagt ttcaaagtta gccacacggt ggtggtctac aacaccgtaa
    22261 acttctactt cagcgatatc tgatacagat tgttggaatt cattgtggtc agtcaagata
    22321 acttgctctg ccccctctgc tttggcagaa gtgataacac gtggtgcttc cacaccaaaa
    22381 tagttcaaga caaaggctgt ttcttcattt ggagttccaa gggcaacagc ttccgtatcc
    22441 aaaccgtaag cttcttttgc aaggtaggca aaagctacag atgatccgat ggcatctgag
    22501 tctggatttt ggtgaccaaa tactagaatc ttggacatga taatacctca ttttgtttat
    22561 tttctttatt gtagcatttt tttcgctttt tgacaaaggt aagaggagtc aaaggactcc
    22621 ccacgattct tcaaaataac tgagtaaatt tctatcttga ttttcagata aaaattcttc
    22681 cttctgtggc ctcttcttac gcttgagaag agcttcagcc gacatggctt cttccttact
    22741 ggcaaaacct tgagcataga taagtttgac tggcaagcgt gctcgtgtat atttggctcc
    22801 cttcccacta ttgtggatag cgaggcgtct tctcacatca gtcgtatagc ctatatagta
    22861 ggatccatca cgacactcca gaacgtacat ataagcctta tgatccataa taaatctctt
    22921 cgatttcggg cgtataagag ccatcatcat tgtggacaat caaaggaggt aagaccttaa
    22981 agccacttgt tgagccatcc ttgatcgcct caatcaaaag catattggct tccttttctc
    23041 tttttggata aacaaactgc aggcgcttag gggctagatt atgtcgtttt aacgtatcca
    23101 aaatatccag aagtcgatca ggacgatgaa ccatggccaa acgcccatta gacttgagaa
    23161 tactctgggc actacgacag atttcttcca aattagtcgt gatttcgtgt cgagccaaga
    23221 gataatgttc actctcgttc agattagaat aaggatccac cttgaaatag ggtggattac
    23281 acaaaatcat atccacctta ctcccctgaa tgtgagcagg catatttttc aaatcatcgc
    23341 agatgacctg catttgctcc tctaatccat tcaaacggac agagcgttca gccatatccg
    23401 ccaaacgctc ctgaatctca acagacaata tctgtgcttg agtacgagtg ctagcaaaaa
    23461 gccccactgc tccattccca gcacagaaat ccacaatcaa ccccttctta ggaaaacgtg
    23521 gaaatcgtga taagagaaca ctatccaccg aatagctaaa aacctctcta ttttgaatga
    23581 ttttgatatc tgtcgaaaag agctggttaa tgcgctctcc tgattttaat aattgttctt
    23641 cttccatggt cctattatag caaatttata ttaacatcac aaaaaatata aaactctaaa
    23701 ctacttcgtc ttttttaaat ggtgcagggc ttctccagtc cagattggta acattcgtcg
    23761 aaagggagca aaaccgtagt taaagcggtc gcttgaaaag cgtctccgtc taggaaactg
    23821 gtacttttct tcctccaaag tgcggataga aagactggct ttccccgtaa attcatctaa
    23881 atccactacc tgaacttgaa cctcttcatc gactttcaag gtttcatgaa tattttcaat
    23941 aaatcctgtc cgaatttctg aaatgtgaat cagccccgta tcacccgtct ctaactcaac
    24001 aaaggcaccg tagggctgaa tccctgtaat acgccccttt agcttatcac cgattttcat
    24061 cttagtcctc gatttcaata gtttcaatta caacatcttc aactggcttg tccatagctc
    24121 ctgtctcaac agcagcaatg gcatccaaga cagcgtaaga tgcttcatca gctaactgac
    24181 caaaaaccgt gtgacggcgg tctaggtgag gtgtcccacc ttgattggca tagatttctg
    24241 caatcggttc tggccaacca ccacgagtaa tttctttctt agaataaggt aggtgttggt
    24301 tttgcacgat aaagaactgg ctgccgttgg tatttggacc agcatttgcc atggaaagag
    24361 caccacggat attgtaaagc tcttctgaga attcatcctc aaaagattcg ccgtagattg
    24421 actcgccacc cataccagtt ccagttgggt ctccaccttg gatcataaag tccttgataa
    24481 tacggtggaa aatgacacca tcatagtagc catcttttga aagagataca aagttagcca
    24541 ctgttttagg agcatgttca gggaaaagct tgatacgtaa gtctccgtga ttggtcttaa
    24601 tagtcgcaag aggaccttct actgtttcaa tgtctacttg tggaaaatgc aattcttttt
    24661 ctaccatacc aaatacttct aaggcatcaa aaatgccatc ttcttctaat gtttttgtaa
    24721 tataatctgc tttttctttg attttatcat gagaaattcc catggcaacg ctgattccag
    24781 cataatcaaa gagttccaag tcgttgagac catctccaaa aaccatgacc ttctctggtt
    24841 tcaagccaag gtgttccaca accttttcca cccccgtcgc tttggagcct gaaatcggca
    24901 caatatcaga cgaatgttga tgccaacgaa ccatgcgaag tttgtctgag agactgtcag
    24961 gcaagtgcaa gtcatctccc ttatcttcaa aagtccacat ctgatagata tcttcttttt
    25021 catggaaatc gggatctaca tctaagtcgg gataaattgg attgatagct tcactcatca
    25081 tatcggtgcg agtcgacaac ttggcatcat gactcccaac caagccatac tcaattcctt
    25141 cttgcttagc ccaagagata tactcctcaa catctgactt ttcaatctga tgctgataaa
    25201 tgacctgacc ttttttatct tcgatataag ctccattcaa agttacaaaa aagtcaggct
    25261 tgagatcacg aatctctgga acaacaccaa aaatgccacg tccagaggcg attcctgtta
    25321 aaattccttt ttcacgcaac tgtttaaaaa cagtgggaat tgtagttgga ataaaccctg
    25381 tctttgaatt ccgcaatgta tcatcaatat caaaaaagac aatcttgatc ttctttgcct
    25441 tgtatcttaa tttcgcgtcc atctcactac ctctttcaat ctaactcttt ccattatatc
    25501 ataaagtagg caaatcccct attttcaaaa agtttatcat ttttatttta atttcttgga
    25561 tgagaaaaaa gacatattta tgaaaaagct ccatcgtgct tttaatgtgt tctcttgttt
    25621 tcaaactcgt aaaaagggag ccactgagcc tgactcgctc tctcatttca aagcttgtga
    25681 aaaaagaccc gttggggtct taattcgctt tcttgttttc aagctcatga aaaagagacc
    25741 caaccgggtc ttttctttaa tcttcgttta cgaaaggcat caaagccatt acgcgagcgc
    25801 gtttgatagc tgttgttact ttacgttggt ttttagctga agttcctgtt acacgacgag
    25861 gaaggatttt cccacgttct gaaacgaaac ggctaagaag ctcagtatct ttgtaatcaa
    25921 catattcaat tttgtttgct gcgatgtaat caactttttt acggcgtttg aatccgccac
    25981 gacgttgttg agccatgttt tttctccttt ataagtttag ttgtccatta gaatggtaaa
    26041 tcatcatctg aaatatccaa tgggtttgtt gctccaaatg gattttcatt acgtgaaaag
    26101 tctggtactg aatttgtagg tgctgaatag tttgcagttg gtgcagagta agctccacct
    26161 gtgtgaccct cacgcacact acggctttcc aacatttgga aattctcagc cacgacctct
    26221 gtcacgtaga cacgttgtcc ttgctggtta tcgtaactac gagtctggat acgacctgtc
    26281 accccgataa gtgagccttt tttagcccag ttagcaagat tttcagcctg ttggcgccac
    26341 ataacgacat taataaaatc agcctcacgt tcaccatttt gactcttaaa tgtacggttt
    26401 actgcaagag taaaagtcgc aactgctaca tttgatgggg tataacgcaa ctcagcgtca
    26461 cgtgtcatac gccctacaag tacaacattg ttaatcatag tttaccttct tacgcgtcaa
    26521 ttttgacgat catgtgacga agaatgtcag cgttgatttt ggaaagacgg tcaaactctt
    26581 taagagctgc atcgtcattt gcttcaacgt taacgatgtg gtaaagtcct tcacggaaat
    26641 cttggatttc gtatgcaaga cgacgttttt cccaagtttt tgattcaaca acagttgcac
    26701 cgttgtcagt caaaatagag tcaaaacgtg ctaccaaagc gtttttagct tcttcttcaa
    26761 tgtttggacg aatgatataa agaatttcgt atttagccat tgatatgttc ctccttttgg
    26821 tctaatgacc ccaagacttt gcaaggggta agtgaggttc gctcacaata aactattata
    26881 ctagaaaaaa tttttttacg caagtaaaaa cactagaatt cgaaaaaacg ccacatgggc
    26941 gttttcctgt tcttatggtt tgatacggtg caacatacgt gggaatggaa tagcttcacg
    27001 gatatgtttt attcctgctg cgaaggttac catacgttcg ataccgatac caaatcctcc
    27061 gtgtggaact gtaccgtatt tacgaaggtc aaggtagaat tcatattctg tacgatccat
    27121 gccaagttca tccatcttag cgacaagggc atcgtaatct tcctcacgca tagacccacc
    27181 gataatttct ccatagcctt ctggagcaag caagtctgca caaagcacgc gctctggatt
    27241 tccaggaact ggtttcatgt agaaggcctt gatggctgct ggatagttca tgacaaatgt
    27301 tggcacacca aagtggtttg aaatccaagt ttcgtgtggt gacccaaagt catcaccatg
    27361 ctcaagatgc tcgtagtcag catcttcatc attttcatgc tcttgcaaga ggtcaatggc
    27421 ttgatcgtaa gtgatacgtt tgaatggctc tgcaatgtag cgtttcaaga gttctgtatc
    27481 acgttccaag gtttccaagg cttgaggcgc gcggtcaaga acaccttgta gaagagcttt
    27541 cacataagct tcttgcaagt caagcgactc atcatgtgtc aagtatgagt actcagcatc
    27601 catcatccag aactcagtca agtgacggcg tgtttttgat ttttcagcac ggaaaactgg
    27661 accaaagtca aagacacgac caagagccat agcccctgct tctaggtaaa gctgacctga
    27721 ttggctcaag taggctggcg ttccgaagta gtcagtttca aagagttctg tagaatcttc
    27781 tgccgcattt cctgaaagaa ttgggctgtc aaacttcata aaaccgttct tgtcaaagaa
    27841 ctcataagtt gcatagataa tagcgttacg gatttgcaac acagctactt gcttacgaga
    27901 gcgtagccac aagtgacggt tatccatcaa aaagtctgtt ccgtgttctt ttggtgtgat
    27961 tgggtagtct tgagattcac cgatcacttc gatgtctgtg atgtccaact catagccaaa
    28021 tttagaacgt tcgtcctctt tgacaatacc tgtcacataa acagacgttt cttggctcaa
    28081 gcgtttgata acatcaaact tctcaagtcc cacttcttca ccaaattttt cgacaaagtt
    28141 tggtttaaaa gccacacctt gaaagaaggc tgttccatca cgcaattgta agaaagcgat
    28201 ttttcctttt cctgatttgt tggcaaccca agcgccaatc gtcacttcct gaccaacata
    28261 gtcttttacg tcaataatcg ttacacgttt tgtcattatt tttccttttc ttttttattc
    28321 tttatggcaa accacctcta tattgttccc atccaggtca atcataaaag cagcatagta
    28381 aatcggatgc tcacttcgat aaccaggaac cccattgtct cgcccacttg cctctatgcc
    28441 agcctcataa caagcctgaa cttcttcctt attttctgct aaaaaagcaa aatgaacagg
    28501 atcttgtgtt ccctgagtca gccaaaaatc accaccagga tgagggctgt tcggggatag
    28561 aaaactaatt agagaactag tcttaaaagc caatttatag tccaaaggaa cgagaaaact
    28621 cctataaaat ccttctgaaa tttgtaaatc ctttacctta atctcaaaat gatcaatcat
    28681 tctcactacc cataaatgct ttcaagcgtt cgactgcttc tttaagcgtg tctaggtctg
    28741 tcgcatagct gaggcggaca ttttctggtg ctccaaatcc agctcctgtt accaaggcca
    28801 cttcggcttc ttctaagata acagttgtaa agtctgtcac atccgtgtag cctttcatct
    28861 ccatggcctt tttgacattt gggaagagat agaaggcccc ttgtggtttg accacttcaa
    28921 atcctggcac ctctgcaagg aggggataga tggtattaag acgttcctca aaggcctgac
    28981 gcatgctttc tacagtatct tgctcacctg atagagcctc aactgctgca tattgggcta
    29041 ctgctgacgg attcgaagtt gtttgacctg caatcttgga catggcagcg ataatgtctg
    29101 cttctccaac ggcataacca atccgccaac cagtcatggc ataggtttta gacacaccat
    29161 tgatgaccac tgtttgcttg cgaatcgctt ccgataggct agaaatcggt gtgaactcat
    29221 gaccattata aaccaagcgg ccatagatat catctgctag gatgagaata tcgttttcta
    29281 cagcccagtt tccaattgcc aagagttcct cacgggtgta aatcatacct gtgggattag
    29341 atggcgaatt cagcaccaaa accttggtct tgtcagtgcg agctgcttct aactgctcta
    29401 cggtcacctt aaagtgattg tcttccttag cagaaacaaa gacgggaacg ccttctgcca
    29461 tcttgacctg atctccatag ctaacccagt atggggttgg gatgatgact tcatcacctg
    29521 gattgaccac agccataaag aagctataga gagaatattt ggctcccgca gcgactgtca
    29581 cttgatttga cgctacagaa tagccgtaaa agcgctcaaa gtagctattg accaccgcct
    29641 taagctctgg cagacctgag gttactgtat aaaaagaagc acgcccatct cgaatcgatg
    29701 caatggcggc atcttggata tttttgggag tagtgaaatc tggctcaccc aaggttagag
    29761 acaaaatatc tctaccctca gccttcagtg ctttggcacg ggctccagca gccaaagtca
    29821 cactttcttc catttctaaa acacggttgg atagtttcat aggccctcct tgttgaccaa
    29881 tgctcctgtt tcaaaatcta ctagataaaa atcagatcct gacttaactt cccagattgg
    29941 cttatcttga taacggccaa aggttatctt gtcaatctcg ccagctccct tttccttaga
    30001 aaccgtttct gctttttctt gtgaaacacc ctgatttagc tgataaacgt aaatcttatg
    30061 gtcatcttta ccaatcagga cagcaagcgc ttcttgctgt ttgttacgac caagaacgct
    30121 gtaataagat tccaagccat tgtataaatc aacctgatca gcctgctcta atcctgcata
    30181 ctgctgagct aatttttctc cttcactttt agctgtttga tagggtttca tgctaagaga
    30241 aaccatatac agaaaggaag cactgataac cacaaacaaa atcgtcatcc ctagaccata
    30301 ctgccacagt agattatttt ttgctttgtt ttgtcttttt ttcactcgtc tattttacca
    30361 tctattaagc tttattacaa gtgaatataa gaatactctt cgaaaatctc ttcaaaccac
    30421 gtcagcttta tctgcaacct caaagctgtg ctttgagcaa ccaattctat ttctcccttc
    30481 aaacaaaacc gattttgaaa gtgaaacagt tcttactttt tcagtcacaa atgattagag
    30541 tttccgaaat tttacaattt tcaaataaac tctgagcaaa tttcttgcaa gttcttttgt
    30601 tttgttgtaa tatattttat aacaacgaga gagttctcga aattttaaga aaaaggagac
    30661 acatcatgtc taaaaaagta ttatttatcg tcggatcact acgtcaaggt tctttcaacc
    30721 accaaatggc gctcgaagct gagaaagcac ttgctggtaa agcggaagtt agctaccttg
    30781 attattcagc ccttcctctc ttcagccaag atttggaagt tccaacacat ccagctgtag
    30841 ctgctgctcg tgaagcagtt ctcgttgcgg atgctatctg gattttctct ccagtctaca
    30901 acttctctat ccctggtaca gtgaaaaact tgcttgactg gctatctcgt gcccttgact
    30961 tgtctgatac acgtggcgtt tctgcccttc aagacaagtt tgtcacagta tcatctgtag
    31021 ccaatgcagg gcacgatcaa cttttcgcta tctacaaaga cctcttgcca tttatccgta
    31081 cacaaggcgt tggtgatttc actgctgcac gtgttaatga ctctgcctgg gcagacggaa
    31141 aattggttct tgaagaaaca gtcctaaact cacttgaaaa acaagctcaa gacttggtcg
    31201 aagcgattca gtaaaaaata gaaaatttta gaaagtctaa atcaattata gccacctaat
    31261 agggtggctt tttatttctc aatcaagatt ttcagacaaa catcagccat ccaaaaaaaa
    31321 ccttgagcgt taccactcaa ggtttttagc agtcttttcc atcataggaa aatcattcta
    31381 agaatattct ttcattcgag atctatcact tatcatcttc tttcgagaaa ttagtgactg
    31441 cttttggctg attaatcttc ttttcttcgt cctacatata ggctcaatag aataccgcta
    31501 cctaaaagaa cagagatata atcagattgg cttccagttt caggtaattt gtccccacgg
    31561 ttttctttac ctgtagttgg tgctactggg ttagcattta ctggagttgc tggttgagcc
    31621 ggtgttggta ctactggttg ttctggaacc gctggtactg gtttaaccgg tacttctggt
    31681 gttgaaacag ctggagttgg ttgtactggc acttctggtg tcggtacatt tggtgttggt
    31741 tgcgctggca caggtttaac cggtacttct ggtgtcggca catttggtgt tggaggaact
    31801 ggtttgtcat ttgatggtgt tactggtttg tcttggcatc cacattttcc atctttaccg
    31861 tctttgccgt ctcgaccatc acgtccatct ctaccatctt tgccatcttt aataactgtt
    31921 tttgtcacag ttccatcaga attgatgatt gtgattgtat gactaccatc accattatct
    31981 tcaacagaaa cttttggtga tttaccatct ttaccgtctt taatcaccat ttctgtctta
    32041 cttccatctg gattagtgat tgtaacaacg tgagttccat cgttattatt tttaacagtt
    32101 acagttggtg aaacgctatc tttgccgtct ttaccatctt tgataataga tttgtattca
    32161 cgaccatcag aatctacgat tgttaatgta tgagttccat ctccgttatc aacgatgttc
    32221 gcttttggtg atttaccatc aaagattgta gttgtcgttc ctttaccatc agcacctgtc
    32281 actttaatag tgtgtgaacc atcgttgtta tcaataactt caagttttgg ttctctacca
    32341 tcacgaactg tagttgttgt agttgttccg tctgagttca caactgtgat agtgtgagtt
    32401 ccatctccat tatccacaac cttagcagtt ggtgatttac cgtcacgaac tgtggtttca
    32461 gaaacagtac cattaccgtt ttccacacga atagtgtaag taccatcttg gttatctcta
    32521 actgttgcta ctggtgattt accatcttta atgattgttt cagtagttgt tccgtcacca
    32581 tttagaacag agatcttatg agttccattt tgttcatcag ttatagtcac ttttggtgat
    32641 ttaccatcac gaactgtggt ttcagttgtc acaccttctg gatttgtaat aacgattgta
    32701 tgacttccgt ctccattatc acgaacagat gcggttggag tacgtccgtc aacaccgtca
    32761 cgtccattct taacaacaaa ctcattctta gttccgtctg ggttagtgat tgttactgtg
    32821 tggcttccat ctggattttc agtagttgtt gctgttgcag ctttaccgtc tttaccatct
    32881 ttgatgatag cgttggtaac attgccgtct ccatctgtaa ctttaacagt atgagttcca
    32941 tcgttgttat ccgttacttc aactttagga gtcttaccgt ctttaccgtt tttaacaaca
    33001 gtttctttag ttgaaccatc tggatttgtc accgtaattg tgtggcttcc atctgggttt
    33061 tctgttgtag tgatattcgc agttttaccg tctttaccat ctttaacaac tgttgttgat
    33121 tcagaaccat ctgggttttg aactgtgata gtgtgagttc catctccatt atcttttgta
    33181 gtaatagttg gagctgaacc atcacgtcca tctataccgt tataaatatc tttactattt
    33241 aatactttat cgacaccttc gtcgtatacc ccattgtcat taacatcatc ataaactgta
    33301 acacggatac cgttacgcgt tggagttgca gcagcatctg tatcgcgtct aattcttgaa
    33361 ggtgaagtaa tatcttctac tttgattttc ggtgcacggc catctttacc attcttacca
    33421 tcttttacag tgaaggttac tggatcttta cctgatgttg tgatagttac aacagtgctt
    33481 tggccatctt gtccacgttg agtagtgatt gtaggagttt gtccatcctg accggttgca
    33541 ccagtttttc ccttagcacc atcttgaaca aagactgtag ttggttgtga accatcatgg
    33601 ttatcaacag tgatttctac acctttatgc cctgcttcat ctttacgaac agctgtaact
    33661 gtaggtgatt ttccatctac tccatctcta attaccgcaa gtggtttttc tggatttaat
    33721 ggttgtcctg ggttagctgg atcttcttgg taaactttag tttctttacc atccttgaca
    33781 gtaagcaatg atttaccatc tcgtccgtcc gcgcctttag caccatcttt aatcatttct
    33841 gaacctagaa gttcatcagt tcctggtgta tatttgccgt cattgttttc atctgtatag
    33901 aatgtcacaa ttgtatgaga tggatttccg ttttttcctt ggacacgaag taaatcaact
    33961 tttggagttt taccgttcag accattttct ccgtccttaa catttactgt aactggatct
    34021 ttacctggaa cagtgaatgt aatgtcagta ctatggccat ctttacctgg agttacagtt
    34081 acttctggag tcttaccatc ttctccgcgt tcacctttgt cacccttagg gcctttgatg
    34141 ttgccctctt tatcccagtt gccgttattc ttaacgaaga cgtcgcctgt ttctgtatta
    34201 acgtatttat cgccgtcttt accttgatgt gcttctgggt tagctttgcc gttcaacacg
    34261 tctttaccgt cacgtccatc acgacctact gcgccatccg cacctttagc tccttgcgct
    34321 ccagttaggc cgcgttcgcc ttggtctcct ttttcgcctt tagcaccatc tgcacctttg
    34381 tcccctttag ggcctttgat gttgccttct ttatcccagt ttccattgtt tttaacatag
    34441 acatcaccgg tttcggtatt aatatattta tctccatttt taccttggtt tggttgtgga
    34501 tttacttttc cgtttaatac atctttacca tcacgacctg cttgtcctgt agctccatca
    34561 cggatcgtag ttgtcacatc tggacttcct ggattatgaa ccgttaatgt atgtgtgccg
    34621 ttttgcccct cagttattgt tactgttggg gttttcccat cagcaccctt ttgtccatcc
    34681 tctacaaatg ttgtttgtgg acgacctcct actggtgtaa ttgttactaa tacaccattt
    34741 ttgccatttt gcacacttcg tgtcgctgta attgttggtg attgtccatt agtaccgttt
    34801 cttccatcag tgatagttgc taatggttgg tttggattaa gtggttgtcc tggtctagcc
    34861 ggatcctcta catagacttt tgtttcagtt ccatttttaa cagcaattag agattttcca
    34921 tctttacctg gagttcctgg attaccttgt tctccttttg gtccttgtgg tcccgctggt
    34981 cctctttgtc catctgcgcc ttttggtcct tgagctccat cacgaccttg aagaccttgt
    35041 tcacctttgt cccctttttc acctttagca ccatctgcaa ttacaacttc ttttaatttc
    35101 ttatcagaag catctaattc attgtttcca tttttatcgt aatagaagat aacagttgtt
    35161 gtcttatctg cgtcatttcg ttgagtcgca actaatggac ttgcgccatc gaaaccatct
    35221 cttacaacag tacttgtaac attacctcta ccgtcgttaa tagtgatagt atgagtgccg
    35281 tcatttttat tatctttaac ggttacggtt ggagttacac cgtcacgacc tgcctgacct
    35341 tgggctcctt tttcaccttt agctccagtt aaaccacgtt cgcctcggtc tcctttttca
    35401 ccttgggctc cagtgagacc gcgttcacct tggtcccctt tttcaccttt agctccagtt
    35461 aaaccgcgtt caccttgggc tcctttttca cctttagctc cttgagctcc agttagaccg
    35521 cgttcgcctc ggtctccttt ttcaccttta gctccttgag ctccagttag accgcgttca
    35581 ccttggtctc ctttttcacc tttagctcca tctttaatag caattttttg aacaagttcg
    35641 tctacacctt cagtataaac accgtttcca tcgttatcaa gatagaaagt gaggttattt
    35701 gtatcaccga ctttattttg atcaacacgt ggttttactg tatcgattag atctttagcc
    35761 acaccaattt gcataatacg tggcttagct tctttagtaa cactattact aatcggcaat
    35821 cctaaaagtg tttcgttacc aaatcgatga actttatagg taatttgacg ttgtcctttt
    35881 tcaccttctc gaactaatct agtttgacct tctggtaact tactagttgg aagatagaca
    35941 gtttggaagt caatgtcttc tgaaacagtc ttattattag taccaccata agggtttgca
    36001 tccaagtata gtgggtttgc tctataataa tagttagagt tactgtatgg gtcattgcta
    36061 gtagcggcac caccaccacc ttggtccacg ttaaaagtaa caggtttcaa acgaacagac
    36121 aaatcaccat ttagattaat gataggcaaa ctaaatctga tagtttgttc cgtatttgtt
    36181 gaaatagcag aggtcatact gtatcctgag tgagatacgt agttggcacc ctgactaata
    36241 gattttgatt gctcccttac tcttggattt gaacttgtga tcgttgcatt tgaaggattt
    36301 ccaaatccat cccctttatc caagataaaa ttattattaa caaactctct agaatctcct
    36361 ggcgcagaat aactaattgt aaagttaaca ctattaccac tacgtactgt tgttacatcg
    36421 taatgaatag aatttccacc acgtgagttc ccgtagccac ggaaactata gctacgacca
    36481 ccttggctaa tatctgcaaa tgcaactgta tttccagaac ctgagacaat tgggttggct
    36541 ggattgctag ccgctctaaa accactatac cctctattaa cattttcctt acggatagct
    36601 ggattttggc gagcatcaga aaggctcaaa cctagtttca agatttcatt aatagatgct
    36661 ggagctgaag ttgtttctac tttgtcagct gtgctagttg gcaaaatagc gctatcaaca
    36721 gctgaacgtt cagttgttgc agctggttta gccccttctt ttgattcaac tgcatcagct
    36781 ttcttcgcta caggcgtttc tgatacagtt tctttattag agttagaacg aagttctaga
    36841 ccaataataa atgattgaat agatgactct gctgctgata attcagcttc agttgcatct
    36901 gcttttccaa gcaagctttg accagcttgg atacttgttt gcaagttagc agcacttgct
    36961 tctgtatata acttgctttc taatttttta gcacgcgaaa gagccgttaa taattttgac
    37021 ttgtcaacgg catcttgatg cgttacttcc tcttttttgt cttttgcttc ttcaactttt
    37081 tctgctggtt tagtaacttc ttcagtttta actggagtcg tttctactgg attagctaca
    37141 gttggagctg cataggtttt ctctttatta gacgcagaaa cctctgctgg tttagtagct
    37201 gcttctcccc taccaacaga aatactattg gtagtttctt gtttgttttc ttccgcttgt
    37261 actgtttgga cactagctgc tacacctaat accaaagcgg taccgagcaa gacactagct
    37321 gcaccaaagt aatacttacg aatagaataa cgttgttgca tgctatacca gtcaaatgat
    37381 tttttatgtg aatgtttcat tttaaact
//
LOCUS       DAVLUM010000007        37254 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLUM010000007 DAVLUM010000000
VERSION     DAVLUM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.007"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            16..86
                     /locus_tag="VYN42_000292"
     tRNA            16..86
                     /locus_tag="VYN42_000292"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="VYN42_000293"
     tRNA            122..195
                     /locus_tag="VYN42_000293"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="VYN42_000294"
     tRNA            202..289
                     /locus_tag="VYN42_000294"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(415..1350)
                     /locus_tag="VYN42_000295"
     CDS             complement(415..1350)
                     /locus_tag="VYN42_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1461434.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1347..2207)
                     /locus_tag="VYN42_000296"
     CDS             complement(1347..2207)
                     /locus_tag="VYN42_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1461435.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2315..4477
                     /locus_tag="VYN42_000297"
     CDS             2315..4477
                     /locus_tag="VYN42_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1461436.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4569..5828
                     /locus_tag="VYN42_000298"
     CDS             4569..5828
                     /locus_tag="VYN42_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1461437.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKEGMVNDLNAFFNPMKADVD"
     gene            5842..6708
                     /locus_tag="VYN42_000299"
     CDS             5842..6708
                     /locus_tag="VYN42_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1461438.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6722..7555
                     /locus_tag="VYN42_000300"
     CDS             6722..7555
                     /locus_tag="VYN42_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1461439.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7556..7636
                     /locus_tag="VYN42_000301"
                     /pseudo
     CDS             7556..7636
                     /locus_tag="VYN42_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7913..9355
                     /gene="gtfA"
                     /locus_tag="VYN42_000302"
     CDS             7913..9355
                     /gene="gtfA"
                     /locus_tag="VYN42_000302"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1461440.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYENLEEYFGDDIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKGLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQIYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9493..10686
                     /locus_tag="VYN42_000303"
     CDS             9493..10686
                     /locus_tag="VYN42_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1461441.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAMHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11371..13350
                     /locus_tag="VYN42_000304"
     CDS             11371..13350
                     /locus_tag="VYN42_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1461442.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13417..14913
                     /locus_tag="VYN42_000305"
     CDS             13417..14913
                     /locus_tag="VYN42_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461443.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPAAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14913..15839
                     /locus_tag="VYN42_000306"
     CDS             14913..15839
                     /locus_tag="VYN42_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461444.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15848..16915
                     /locus_tag="VYN42_000307"
     CDS             15848..16915
                     /locus_tag="VYN42_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461445.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16926..17852
                     /locus_tag="VYN42_000308"
     CDS             16926..17852
                     /locus_tag="VYN42_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461446.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18343..18858
                     /locus_tag="VYN42_000309"
     CDS             18343..18858
                     /locus_tag="VYN42_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1461447.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TTPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            18880..19281
                     /locus_tag="VYN42_000310"
     CDS             18880..19281
                     /locus_tag="VYN42_000310"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461448.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19293..20170
                     /locus_tag="VYN42_000311"
                     /pseudo
     CDS             19293..20170
                     /locus_tag="VYN42_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20183..20986
                     /locus_tag="VYN42_000312"
                     /pseudo
     CDS             20183..20986
                     /locus_tag="VYN42_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(21019..21729)
                     /gene="treR"
                     /locus_tag="VYN42_000313"
     CDS             complement(21019..21729)
                     /gene="treR"
                     /locus_tag="VYN42_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1461449.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21914..23881
                     /gene="treP"
                     /locus_tag="VYN42_000314"
     CDS             21914..23881
                     /gene="treP"
                     /locus_tag="VYN42_000314"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1461450.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24059..25684
                     /gene="treC"
                     /locus_tag="VYN42_000315"
     CDS             24059..25684
                     /gene="treC"
                     /locus_tag="VYN42_000315"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1461451.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRSLNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25940..26188
                     /locus_tag="VYN42_000316"
     CDS             25940..26188
                     /locus_tag="VYN42_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1461452.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26395..27189
                     /gene="racE"
                     /locus_tag="VYN42_000317"
     CDS             26395..27189
                     /gene="racE"
                     /locus_tag="VYN42_000317"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1461453.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27186..28157
                     /locus_tag="VYN42_000318"
     CDS             27186..28157
                     /locus_tag="VYN42_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1461454.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28133..28654
                     /locus_tag="VYN42_000319"
     CDS             28133..28654
                     /locus_tag="VYN42_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1461455.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28651..29112
                     /locus_tag="VYN42_000320"
     CDS             28651..29112
                     /locus_tag="VYN42_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1461456.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29103..29843
                     /gene="xerD"
                     /locus_tag="VYN42_000321"
     CDS             29103..29843
                     /gene="xerD"
                     /locus_tag="VYN42_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1461457.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29843..30571
                     /locus_tag="VYN42_000322"
     CDS             29843..30571
                     /locus_tag="VYN42_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1461458.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30590..31159
                     /locus_tag="VYN42_000323"
     CDS             30590..31159
                     /locus_tag="VYN42_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1461459.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31146..31868
                     /locus_tag="VYN42_000324"
     CDS             31146..31868
                     /locus_tag="VYN42_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1461460.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLHP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31868..32110
                     /gene="yidD"
                     /locus_tag="VYN42_000325"
     CDS             31868..32110
                     /gene="yidD"
                     /locus_tag="VYN42_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1461461.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32335..33300)
                     /locus_tag="VYN42_000326"
     CDS             complement(32335..33300)
                     /locus_tag="VYN42_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1461462.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGVADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33396..34148)
                     /locus_tag="VYN42_000327"
     CDS             complement(33396..34148)
                     /locus_tag="VYN42_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1461463.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34145..35101)
                     /locus_tag="VYN42_000328"
     CDS             complement(34145..35101)
                     /locus_tag="VYN42_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1461464.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILIGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(35091..36050)
                     /locus_tag="VYN42_000329"
     CDS             complement(35091..36050)
                     /locus_tag="VYN42_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461465.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36473..37174)
                     /locus_tag="VYN42_000330"
     CDS             complement(36473..37174)
                     /locus_tag="VYN42_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV1461466.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRATVD
                     NRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
BASE COUNT        10743 a         6941 c         8287 g        11283 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagagc caataaaact tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatat cgtttatatt ataattgtgt tattttactt
      421 ccaactattg agagaaattt cgccactatt tagccagatt tcttttccgt tatcacattg
      481 aactaaaagt tttccatttt ctgagatgtc tttagcaagt cccttgtagt ctttttgctc
      541 tagtgtgaaa gtgacttctt ttcctagaat gaatgactgt tttttgtata ggtataatag
      601 ctcttctgct ggtgtttcga agaaagcacg ccagatttct atgatcaatt cattccttgt
      661 tataggagct gtagctttaa ataagctggc agctttttct tttaattcct gagggaagtc
      721 tttaatagtg aaattgatac ctactccaat aatgatatct gtgactaagc cagtttctac
      781 agaggtcatt gcttcagtaa ggattcctcc aattttatga ttgtttagat agatatcatt
      841 gacccatttt atgtcgacat ctattaaagt taggttctta atggctttgt agacagctcc
      901 agctacaagt agtgtgtagg atggtaattt gtcatagggg agatttggtt taagatggag
      961 tgtcatataa ataccacctt gtggtgagta gaaggaacgt tgaaaacggc ctcggcctgc
     1021 tgtttgatag gaagctagat agagggtatt tgcttcatgg cctaaatcaa ttgcttcttt
     1081 tgcatctagt tgtgttgatt ttgtttcggg tttaaagctg actttaattg gaagattttc
     1141 ttctagaatc tctggaagaa taaggtcacc attcatcagt ttatatcctc tatttttgat
     1201 actatcaatt tcaatgcctt cttgttctag tcgcttgatg gctttccaaa ttgctgttcg
     1261 gcttagggat agtttttctg cgattttttc tccgctgata tagtcggttt ctttagatag
     1321 gatttggtag acagcttggt aggatttcat aatgttgcct ttcttactag ttggtattga
     1381 gagtattctt ttcttgtatg acttggagtc tgattaaagt attgtttata agctttcgaa
     1441 aaatggagtg gatctgaaaa acctaccgag tatgcaatta ccttgatgga ctcttgggta
     1501 ttttcgagaa gttgtctagc tcggtgcatt cgaacgtaga gtaggtattc tttgggtgat
     1561 aaggtattaa attctttgaa tacgcttgat aagtagcttc tgtgaacgga tagttctttt
     1621 gctaaatctt gaattgtaag tgattgagga tagtggctat caattaatcg tttgcattca
     1681 agatagagtt ggtgggttga tgaaatattc ttttttttct gattgggagc aatagttccc
     1741 agatgaaaca tcagttcatg aagttgtccc atgatatgga gttgagctaa ttcacttgat
     1801 tttgtaatct gagcgaagcg gacaatgtct gagatgagtt ttgcagtagt ctgggtatga
     1861 caagtttcag attggatgag ataggattga tcagaaattt gggaaagagc aaaataatca
     1921 ggggctttcc ctccagtgat tcctaaccag tagtaggccc aaggttcttt actatctgct
     1981 tgataaaagg ttagttcctc tggttttaat agaaagaaat ctccttcttt taaatcaaca
     2041 attttaccct tgtaatgaaa ttttccttgt cctttagtaa tgtaatgtag aacgtatgta
     2101 tcacgaatgg ctggaccaaa agagtaatta ggtgtgcatt cctcatatcc ataaaagctt
     2161 agggcaaggt cgattgttcc agtctggtat tctgaaaaaa ctaacatgtg ctacctccta
     2221 cctaacattt taccatattc ttgagacatt tttctatttt ggaaagcgat ttcaggtgat
     2281 aaaatataat caataaagtg atgaggtgaa gtaaatggga gttaggatag agaataatct
     2341 attttatgtt gagagtaaaa atctaagttt gattattgaa aatcgaaatg gctacttact
     2401 tttgaaacat ttaggaaaga ctattaagaa ctataaaggt tccaatagtg tttatgaacg
     2461 agaccatgcc ttttcaggaa atccaacggc tactaatcga acctttagtt tagatactca
     2521 gcgacagatt tttggacaac atggcttagg agattttagg aaaccaacta tacaggttca
     2581 gcatagtgta actgaagtaa cagactttcg atttgtagaa gcaaagattt taaaaggtca
     2641 gaatggtcca cagggcttac cttctccaca tagcatggac gatacagaga ctcttgtctt
     2701 aatgttagaa gattctaagg ctcaacttag tctgactttg tattatacta cttttaataa
     2761 tgatgcgact attgctagct acagtaaatt agataataat agtaatcagg aagttgtcat
     2821 ccataaagat ttttctttta tggctgattt tccagctgca gattacgaaa tagtaactct
     2881 gcagggtgct tatgctcgtg aaaagactgt tagacgtcaa caggtagaac aaggaatctt
     2941 ttcgattagt tcaaaccgag gtgcttctgg tcatgctcaa acaccagctc ttctactatg
     3001 cgaacaagga gtcacagagg atgctgggaa tgtgtttgct attcaactaa tgtatagtgg
     3061 caactttgaa gcttttgttc aaaaaaatca attgaatgaa gttcgggtgg ctattggcat
     3121 taatccagaa aacttttctt ggaagttagc ccctgaggaa tactttgaaa caccggtagc
     3181 tttagtgact cattcagatc agggattaac tggtattagt catgaaagtc agaattttgt
     3241 actgaagcac attattctaa gtgaattttc taaaaaagaa cgtccaattc taatcaataa
     3301 ctgggaagct acttactttg actttcagag agaaaaactg ttagagttag cagatgaagc
     3361 taagaaagtt ggcattgaac tttttgtatt agatgatggt tggtttggca atcgttttga
     3421 tgataatcgt gctttaggtg attgggttgt taatgaggaa aaactgggtg gaagtctaga
     3481 aagtctgatt tcagctatcc atgaaagagg tttgcagttt ggactttggt tagaacccga
     3541 aatgatttct gtagatagtg atttgtatcg tcaacatcct gactgggcta ttcaggttcc
     3601 tgattatgag catacttatt ctcggaatca attagtactt aatcttgcca atcctcaggt
     3661 agtagaatac ttgaaaagtg tcttagatca actcctatct tatcatgaga ttgattacat
     3721 taaatgggat atgaaccgca atatcactaa gctagggaat ggattaactt atctagagac
     3781 acagatgcaa tctcatcagt acatgctggg actttacgaa ctcgtttctt atctgacaga
     3841 gaagcacagc catattctct ttgagtcctg ctctggtggt ggtggacgaa atgatcttgg
     3901 tatgatacgc tatttcccac aagtctgggc tagtgataat actgatgcca ttgcacgttt
     3961 accaattcaa tacggttcat cctatctcta tccaaccatt tctatggggg ctcatgtgtc
     4021 agcagtaccg aatcatcaga tgggacgaat gacaccatta gaaacacgtg gccatgtagc
     4081 aatgatggga aatttgggct atgagcttga tttgacaaat ttatcagatg aagagaaagc
     4141 tacgattgct aatcaggtga acttgtataa agaattacga ccagtagttc agttaggaca
     4201 gcagtataga ctaattaatc ctgatactgc atccaatgaa gcagctgtac aatttaatta
     4261 cggaaatcaa acgattgtaa cctacgttcg cgttttatct gttgtagaga ccatggaaac
     4321 aactttaaaa ttaaaagatt tggatgaaga gggactatat aaattacagg aaaatggcga
     4381 agtttactca ggtgcagaac taatgtatgc gggcttaact gttatcttat cccaaggaga
     4441 ttttttgagt agacagtata tttttagaaa actatgatat gtactgaccc caaaagttag
     4501 atttattctg tctaactttt ggggtgcagt tcaataaggg tgtataaatt tataaaggag
     4561 gctttctaat ggaatggtat aaaaaaatcg gacttcttgc aactacaggt ttagctttgt
     4621 ttgggctcgg cgcttgctcc aactatggta aatctgcgga tggcacagtg accatcgagt
     4681 atttcaacca gaaaaaagaa atgaccaaaa ccttggaaga aatcactcgt gattttgaga
     4741 aggaaaaccc taagatcaag gtcaaagtcg tcaatgtacc aaatgctggt gaagtattga
     4801 agacacgcgt tctcgcagga gatgtgcctg atgtggtcaa tatttaccca cagtccatcg
     4861 aactgcaaga atgggcaaaa gcaggtgttt ttgaagattt gagcaacaaa gactacctga
     4921 aacgcgtgaa aaatggctac gctgaaaaat atgctgtaaa cgaaaaagtt tacaacgttc
     4981 cttttacagc taatgcttat ggaatttact acaacaaaga taaattcgaa gaactgggct
     5041 tgaaggttcc tgaaacctgg gatgaatttg aacagttagt caaagatatc gttgctaaag
     5101 gacaaacacc atttggaatt gcaggtgcag atgcttggac actcaatggt tacaatcaat
     5161 tagcctttgc gacagcaaca ggtggaggaa aagaagcaaa tcaatacctt cgttattctc
     5221 aaccaaatgc cattaaattg tcggatccga ttatgaaaga tgatatcaag gtcatggaca
     5281 tccttcgcat caatggctct aagcaaaaga actgggaagg tgctggctat accgatgtta
     5341 tcggagcctt cgcacgtggg gatgtcctca tgacaccaaa tgggtcttgg gcgatcacag
     5401 cgattaatga acaaaaaccg aactttaaga ttgggacctt catgattcca ggaaaagaaa
     5461 aaggacaaag cttaaccgtt ggtgcgggag acttggcatg gtctatctca gccaccacca
     5521 aacatccaaa agaagccaat gcctttgtgg aatatatgac ccgtccagaa gtcatgcaaa
     5581 aatactacga tgtggacgga tctccaacag cgatcgaagg ggtcaaacaa gcaggagaag
     5641 attcaccgct tgctggtatg accgaatatg cctttacgga tcgtcacttg gtctggttgc
     5701 aacaatactg gaccagtgaa gcagacttcc ataccttgac catgaactat gtcttgaccg
     5761 gtgataaaga aggcatggtc aatgatttga atgccttctt taacccgatg aaagcggatg
     5821 tggattagga gtagagagac tatgaaaaaa gtattacaaa aatattgggc atgggctttt
     5881 gtggtcatcc ccctcttgtt acaagcaatt ttcttctatg tgccgatgtt tcaaggagcc
     5941 ttttacagtt ttaccaactg gacaggattg acttataact acaaatttgt cggcttaaac
     6001 aactttaagc tcctcttcat ggatccaaaa ttcatgaatg cgattggctt taccgcaatc
     6061 attgcgattg ccatggtggt tggtgagatt gcactcggga tcttcattgc gcgtgtcttg
     6121 aattctaaaa tcaaaggcca aaccttcttc cgtgcttggt tcttcttccc agctgtttta
     6181 tctggtttga cagtggcttt gatcttcaag caagtcttca actacggtct tccagcgatt
     6241 ggaaatgccc ttcatattga atttttccaa accagtcttt tagggactaa gtggggagca
     6301 atctttgcgg ctgtctttgt ccttctttgg caaggggtgg ctatgcccat catcatcttc
     6361 ctagctggtt tgcaatctat tccaactgag attacagagg cagcaaggat tgatggtgcg
     6421 actagcaagc aagttttctg gaacattgaa ttgccttact tgctaccaag tgtctctatg
     6481 gtctttatcc tagccctaaa aggtgggctg actgcctttg accaagtctt tgccatgacc
     6541 ggtggtggtc caaacaatgc cacaacctca cttgggctct tggtttataa ctatgccttt
     6601 aaaaacaacc aattcggtta tgccaatgcc attgccgtaa tcttgttctt cttaattgta
     6661 gtgatttcga tcatccaatt gagagtatct aagaaatttg aaatttaaga ggagaagcat
     6721 gatgaaacaa gatgaaagaa aagccctgat tggcaaatac attctattga ttctaggatc
     6781 ggttctgatt ttagtgccgc tccttgctac cctttttagt tccttcaaac ccactaagga
     6841 tattgtagat aatttctttg gctttccaac caacttcaca tgggacaact ttagccgtct
     6901 cttagctgat gggattggag gctattattg gaactctgtc gtcatcactg tcttgtcttt
     6961 acttgcagta atgatcttta tacctatggc agcctactcc atcgctcgca atatgagtaa
     7021 aagaaaagcc tttaccatca tgtataccct cttaatcctc ggaatcttcg tacctttcca
     7081 agtcatcatg attccgatta cggttatgat gagtaaactc ggtttggcta atacctttgg
     7141 tttgatctta ctctacttga cctatgcgat tccacagacc ctctttctct atgttggcta
     7201 tatcaaaatc tcgattccag aaagtctgga tgaagcagca gagatcgatg gggctaatca
     7261 atttacaacc tatttccgca tcatcttccc aatgatgaaa ccgatgcatg cgacaaccat
     7321 gatcatcaat gccctttggt tctggaatga cttcatgttg ccactccttg tcttgaaccg
     7381 ggattccaaa atgtggactc tgcctttgtt ccaatacaac tacgcaggcc aatatttcaa
     7441 cgactacgga ccaagctttg cctcttacgt ggtcggcatt atcagtatca ccattgtcta
     7501 tctcttcttc caacgccata tcatttcagg aatgagcaac ggggcagtga agtaatactc
     7561 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga
     7621 ggttgtggat gaaactgacg aagtcagtaa ccatacctac ggtaaggtga agctgacgtg
     7681 gtttgaagag attttcgaat agtataagaa gagctcatgg aatctatagt ctttgacaca
     7741 gaggaagagt tcagcttgtt gataattcta tgtagaaaac aagaaagtag tactttgttt
     7801 atcacagtct atattagtac gagtttgatg ataaatagag atttaaaatg aattttattt
     7861 atgaagccag atcatatgag acttggcttc aattagaaaa aggagagtaa tgatgccgat
     7921 tcagaataaa acaatgttga ttacctattc agatagtctg ggaaataatc ttaaagactt
     7981 atatgagaat ttggaagagt attttggaga tgatattgga ggagttcacc ttctaccatt
     8041 tttcccatca acaggtgatc gtggatttgc gccagttgac tacgacgaag tggattcagc
     8101 ttttggtgat tgggaggatg ttaagcgttt aggtgagaaa tattatctta tgtttgactt
     8161 tatgattaat catatttctc gtcaatctaa gtattataag gactatcaag aaaaacatga
     8221 agccagtgaa tttaaaggtc tctttttaaa ctgggataag ttttggccag aaaaccgtcc
     8281 gacacagtct gatgtagatt taatttacaa gcgtaaggat cgtgcaccaa agcaagagat
     8341 tgtgtttgaa gatggatcag tggaacattt gtggaatacc tttggtgagg agcagattga
     8401 tcttgatgtg accaaagaag taactatgga atttatccgt aagaccattc agcacttggc
     8461 aagtaatggg tgtgatttga ttcgtctaga tgcctttgct tatgcagtga agaaattgga
     8521 tactaatgat ttctttgtgg aaccagatat ttgggattta ttggacaaag ttcgagatat
     8581 cgctgctgag tatgggacag agcttttacc tgagattcat gaacactatt cgattcagtt
     8641 taaaatagca gaccatgatt actatgttta tgattttgct cttccaatgg tgacacttta
     8701 tactctttac agttccagaa cagagcgttt ggctaagtgg ttaaagatga gcccgatgaa
     8761 gcaatttacg acgctagata cccatgatgg gattggagta gtagatgtca aggatatcct
     8821 gaccgatgag gagattgact atgcttcaaa tgaactctat aaggttggag ccaatgtcaa
     8881 acgtaagtac tctagtgccg agtataacaa cttagatatc taccaaatca attcaaccta
     8941 ctattcagcg cttggagatg atgatgtcaa gtattttctc gctcgtctaa ttcaagcttt
     9001 tgccccaggt attcctcaga tttactatgt gggtctatta gcaggcaaga atgacttgaa
     9061 attattagaa gaaactaaag aaggtcgaaa tattaatcgt cattactata gcaacgagga
     9121 aatagcaaaa gaagtgcaac gacctgttgt gaaggccctt ctcaatctat tttctttccg
     9181 taaccgttca gaagcctttg atctagaagg gactactgag atagagacac caacagctca
     9241 cagcattgta atcaaacgtc aaaataaaga taagtccgta acagcagtag tagaaattga
     9301 tttgcaaaat cagacttatc gggtaattga gaatggagtt gaagtatcat tttgaagcct
     9361 tgatatggtg gataaaatag ggtttttatt ttggaaaacg tttcctttgt tttcaaattg
     9421 ctaaaaaagt ggtacaatat aggatagctt actattatct gaatcagctg atttggagag
     9481 aaaggattca ttttgaaatc aataggcttt attgaaaagc tgaaggggtt gtctagtaaa
     9541 gagctgattt tattgggaat tatcctgagt atctttttac ccttttatct ttttgtagtt
     9601 gtactctgtt tatatattat cagtttgatt tttacaggag acatgaaaag tattcttcag
     9661 aaaatggggg agcatccgat gctgcttctt tttcttagct atagtactgt tatatccatt
     9721 cttgcacaaa attggatggg tcttgtggct tcagtaggaa tgtttctatt tactattttc
     9781 tttttgcact atcagtcgat tttatcccat aaattctttc gattgatttt gcagtttgtc
     9841 ttgtttggta gtgtcttgtc agctgctttt gccagtttag aacatttcca aattgtgaag
     9901 aaatttaact atgcttttct ttcacccaat atgcaggtgt ggcatcagaa ccgggcagaa
     9961 gtgaccttct ttaatcctaa ttattatgga attatttgtt gtttctgtat tatgattgct
    10021 ttctatctgt ttacaacgac caagttgaat tggttgaaag tattctgtgt gattgcaggc
    10081 tttgttaatc tctttggttt gaactttact caaaatcgaa ctgcctttcc tgctattatc
    10141 gctggagcaa ttatctatct ctttacgact attaaaaact ggaaggcctt ttggcttagt
    10201 attggggtct tcgcgattgg tttgagtttc ctcttttcta gtgatttggg agttcgaatg
    10261 ggtactttag actcttctat ggaagaacgc atttctatct gggatgctgg gatggccttg
    10321 tttaagcaaa atcctttttg gggtgaaggg ccattgacct atatgaactc ttatcctcgg
    10381 atacatgctc cttatcatga acatgcccac agtctttata ttgatacgat tctgagttac
    10441 ggaattgtgg ggactatttt attagttttg tcttctgttg ctcctgttcg cttgatgatg
    10501 gatatgagtc aggagtcggg gaaacgtccg attatcggcc tttatctatc tttccttaca
    10561 gtggttgcta tgcacggaat ttttgacttg gctctcttct ggattcagtc aggctttatt
    10621 ttcttgctag ttatgtgcag tattccattg gagcatcgaa tgttggtatc ggacatgacg
    10681 gattaagttt tataagtttg aaatcttcta ccttgggtag gagatttttt atacgatggg
    10741 catgtcgtgc atctgaggtg taagtcctct gtagggctcc actaccggtg aatacaatag
    10801 cgctccccaa gcctgactat cgtgaggtag cggattaaaa tggtctgggg atagatcgtt
    10861 ttaagtctga cgcaggaaat aagaattgtc agagaaagca atagtgaaat cgtaggctat
    10921 gaatagaaac gtgatagcga ggagcatata gtggataagg tagcgagaaa ttttaaagta
    10981 taaaagatag tcttaatcta tatatgtaaa tcacaaaagt aattgaattc gggataaggt
    11041 tggtgtgaaa agacatagta aactgaatct tgaatactag aatgatactt ctacaatatt
    11101 gttataattt aatttgaatt ccaaaatcac attgttccgt ccgtatttca ttttactgta
    11161 tgtcttccta aactccaaag tttctgcgtc aaatttccta ttttcactgt agtctttgac
    11221 acttcgaacg acaatttgaa tcatatattc aaaaaaaatg aaaaatttgt gccaacaagc
    11281 ctaaatattc tgaaaatttg tttgattttt aatggataat gtgatataat ggttgtcaat
    11341 ctataattca cataaacaga ggagtagaaa atgaaaaaaa atcgtgtatt tgctacagca
    11401 ggtcttgttt tattagcagc aggtgtactt gcagcatgca gttcttcaaa atcatctgat
    11461 tcatcagccc ctaaagctta tggctatgtt tatacagcag acccagaaac cttggactac
    11521 ctgatttcaa gtaaaaatag tacaacagta gtgacttcaa atgggattga tggtttattc
    11581 actaacgata attacggtaa tcttgctcct gcagttgcag aggattggga agtctctaag
    11641 gatggtttga cctacactta taagattcgt aaaggggtta aatggtttac ctctgatgga
    11701 gaagaatatg cagaggtgac ggctaaagat ttcgtgaacg gtttaaaaca cgcagcagat
    11761 aaaaaatcag aagctatgta tttagctgaa aattcggtta aaggcttggc agattatcta
    11821 tcaggaactt caacagattt ttcaacagtt ggtgtcaagg cggttgatga ttatacgtta
    11881 caatacactt tgaaccagcc tgaaccgttc tggaactcta agttgaccta ttctattttc
    11941 tggcctctga atgaagaatt cgaaacatca aaaggaagcg attttgctaa accaacagat
    12001 ccgacatcct tgctttataa tggtccattc ttgttgaaag ggttgactgc aaaatcttct
    12061 gtagagtttg taaaaaatga gcaatattgg gataaagaaa atgtccacct agatactatc
    12121 aatctagctt actatgatgg atcagatcag gagtcgctag agcgtaactt cactagtgga
    12181 gcttatagtt atgcccgtct ttaccctacc agctccaact attctaaggt tgcagaagaa
    12241 tacaaggaca atatctatta cacacaatca ggctctggga ttgctggtct gggtgtgaat
    12301 attgatcgcc aaagttacaa ctatacttct aaaactacag attcagagaa agtagctact
    12361 aagaaggcat tgcttaacaa agatttccgt caagccttga attttgctct tgatcgctca
    12421 gcttactcag ctcaaatcaa tggtaaagat ggagcagctt tagcagttcg taatttattt
    12481 gtaaaaccag actttgtttc agctggtgag aagacctttg gtgatttagt cgctgctcaa
    12541 cttcctgctt atggtgatga gtggaaaggt gtgaatttag ctgatgggca ggatggttta
    12601 ttcaatgctg acaaggccaa ggcagagttt gcgaaagcta agaaagcttt agaagcagac
    12661 ggcgttcagt ttcctattca tctggacgtt ccagtagacc aagcatcaaa aaactacata
    12721 tctcgtattc agtcctttaa acaatctgta gaaacagttc ttggtgttga aaatgtcgtt
    12781 gttgatattc aacaaatgac aagtgatgaa ttccttaata ttacttacta tgctgccaat
    12841 gcttcatctg aggattggga tgtatcagga ggagtttcat gggggccaga ctatcaagac
    12901 ccatctactt acctggatat tttaaaaaca actagcagtg aaactacaaa aacatattta
    12961 ggatttgata atccaaatag cccttcagta gttcaagttg gtttgaaaga atacgataaa
    13021 ttagttgatg aagctgccag agagacaagc gacttgaatg tccgttatga aaaatatgca
    13081 gcggctcaag catggttgac agatagttca ctctttattc ctgctatggc ttcttctggt
    13141 gcagcaccag tgctttcacg aattgttcca tttactggag cttctgcgca aacaggctct
    13201 aaggggtcag atgtttactt caaatatttg aaattacaag ataaagtggt gactaaggaa
    13261 gagtatgaaa aagctcgtga aaaatggttg aaagaaaaag ctgaatcaaa tgagaaagct
    13321 caaaaagaat tggcaagtca tgtgaagtaa ataatttcta atagaacttt ctctccatga
    13381 ggagaaggtt cttttgggat ttttaaagga aataatatga aaaaatatat ttttatgcgt
    13441 gttttgcggt cattggtttc gattttctta gtaacgactt tgacctacac gattatctat
    13501 accttggttc ctcgaaaatt gattttcaag caggatccta actataataa aattgcgaca
    13561 acggctgata aacgtgataa ctatgaaaat actgtgtttg agcgtatggg ctacattgag
    13621 tattacgata ctaaagagtt gcaagaaaag gcaagtagca tggattcttc tgtaacagta
    13681 gaagcaaatg cgaccaataa agctatttat gaaaagtaca tcaatcaatt aggtcatggt
    13741 tggactttgg gagaatttac tgaaagtggt caattctatg ctactcgtga aattccaatt
    13801 tttgaacgtg tttttcactt ctatgctaac ttgattgaca ttgaccatac aaataaaatc
    13861 caagaccctg aaaatccaga cttgaaacgc taccttcgtt ttgaaaatga tccagctatc
    13921 ggatggtcat tggtcggttc aggaactaaa cataaatatc tcttgtactt taacagtcag
    13981 ttcccatttg ttcatcaaaa ctttgtgaac ttgaatttag gtgactctta cccaacctat
    14041 gctaatacac cagttcttca ggttattact caaggtcaag gacaaaccaa aactgcccaa
    14101 gttcagttcc caacaggtaa gaaaacgtct tctgtaaata tttactcaag aacctacaag
    14161 tcacctagtc aggctgactc tcgtgaagta gctagctatg ggaaagatga tccttataca
    14221 gcgactgaaa gtaattacca atatccatct atgattgtca gctctgctat tactggtttg
    14281 attggtttgg ttcttgccta tgctcttgcc gtgccacttg gttcagccat ggctcgtttc
    14341 aagaacactt ggattgatag cctctcaaca ggggctttga ccttcttgct tgctcttcca
    14401 acgattgcct tggtttacat cgttcgattg attggatcat ctattgccct tccagattca
    14461 ttccctatct tgggagctgg agattggcgt tcttacgttt taccagcagt catccttggt
    14521 ttgttgggtg ctcctggtac agccatttgg attcgtcgtt acatgattga cttgcaatct
    14581 caagactttg ttcgtttcgc tcgtgcaaaa ggtttgtctg aaaaagaaat ttcaaacaaa
    14641 cacatcttta aaaatgccat ggttccgctg gtttcaggaa ttcctgctgc cattattggg
    14701 gttatcggtg gtgcaaccct tactgaaaca gtcttcgcct tcccaggtat gggtaaaatg
    14761 ttgattgact ctgtaaaagc atctaataac tctatggtcg ttggtcttgt cttcatcttt
    14821 acatgtattt ctatcttctc acgtcttttg ggagatattt ggatgactat tattgaccca
    14881 cgtattaaat tgactgagaa aggaggcaaa taatgtctac aatcgataaa gaaaaatttc
    14941 agtttgtaaa acgtgatgat tttgcctctg aaactattga tgcgccagca tattcttact
    15001 ggaaatcagt gtttaaacaa tttatgaaga aaaaatcaac tgtagtcatg ttgggaatct
    15061 tggtagccat cattttgata agtttcatct acccaatgtt ttctaagttt gatttcaatg
    15121 atgtcagcaa ggtaaacgac tttagtgttc gttatatcaa gccaaatgcg gagcattggt
    15181 tcggtactga cagtaacggt aaatcgctct ttgacggtgt ctggttcgga gctcgtaact
    15241 ccatcctcat ttctgtgatt gcgacagtga ttaacttggt tatcggtgtt tttgtcggtg
    15301 gtatttgggg tatttcaaaa tcagttgacc gtgtcatgat ggaagtttac aacgtcatct
    15361 caaacatccc acctcttttg attgttattg tcttgactta ctcaatcgga gctggattct
    15421 ggaatctgat ttttgccatg agcgtaacaa catggattgg tattgccttc atgatccgtg
    15481 tgcaaatctt gcgctatcgt gacttggaat acaacttggc gtcacgtact ttgggaacac
    15541 caaccttgaa gattgttgcc aaaaatatca tgcctcaatt ggtatctgtt attgtgacaa
    15601 ccatgactca aatgcttcca agctttatct catacgaagc cttcttgtct ttcttcggtc
    15661 ttggattacc gattacagtg ccaagtttgg gtcgtttgat ttcggattat tcacaaaacg
    15721 taacaaccaa tgcttacttg ttctggattc cattgacaac ccttgtcttg gtatccttgt
    15781 cccttttcgt agttggtcaa aacttagcgg atgctagtga tccacgtaca catagatagg
    15841 agtagaaatg acaaaagaaa aaaatgtaat tttgactgct cgcgatattg tcgtggaatt
    15901 tgacgttcgt gacaaagtat tgacagccat tcgcggcgtt tcccttgaac tagtcgaagg
    15961 agaagtatta gccttggtag gtgagtcagg atcaggtaaa tctgttttga caaagacctt
    16021 cacaggtatg ctcgaagaaa atggtcgtat tgcccaaggt agtattgact accgtggtca
    16081 ggacttgaca gctttatctt ctcacaagga ttgggaacaa attcgtggtg ctaagattgc
    16141 gactatcttc caggacccaa tgactagttt ggaccccatt aaaacaattg gtagtcagat
    16201 tacagaagtt attgtaaaac accaaggaaa aacagctaaa gaagcgaaag aattggccat
    16261 tgactacatg aataaggttg gcattccaga cgcagataga cgttttaatg aatacccatt
    16321 ccaatattct ggaggaatgc gtcaacgtat cgttattgct attgcccttg cctgccgacc
    16381 tgatgtcttg atctgtgatg agccaacaac tgccttggat gtaactattc aagctcagat
    16441 tattgatttg ctaaaatctt tacaaaacga gtatcatttc acaacaatct ttattaccca
    16501 cgaccttggt gtggtggcaa gtattgcgga taaggtagcg gttatgtatg caggagaaat
    16561 cgttgagtat ggaacggttg aggaagtctt ctatgaccct cgccatccat atacatggag
    16621 tctcttgtct agcttgcctc agcttgctga tgataaaggg gatctttact caatcccagg
    16681 aacacctccg tcactttata ctgacctgaa aggggatgct tttgccttgc gttctgacta
    16741 cgcaatgcag attgacttcg aacaaaaagc tcctcaattc tcagtatcag agacacattg
    16801 ggctaaaact tggcttcttc atgaggatgc tccgaaagta gaaaaaccag ctgtgattgc
    16861 aaatctccat gataagatcc gtgaaaaaat gggatttgcc catctggctg actaggagga
    16921 aggaaatgtc tgaaaaatta gtagaaatca aagatttaga aatttccttc ggtgaaggaa
    16981 gtaagaagtt tgtcgcggtt aaaaatgcta acttctttat caacaaggga gaaactttct
    17041 cgcttgtagg tgagtccggt agtgggaaaa caactattgg tcgtgctatc atcggtctaa
    17101 atgatacaag taatggagat atcatttttg atggtcaaaa gattaatggt aagaaatcgc
    17161 gtgaacaagc tgcggaattg attcgtcgaa tccagatgat tttccaagac cctgccgcaa
    17221 gtttgaatga acgtgcgact gttgattata ttatttctga aggtctttac aatcaccgtt
    17281 tatttaagga tgaagaagaa cgtaaagaga aagttcaaaa tattatccgt gaagtaggtc
    17341 ttcttgctga gcacttgact cgttaccctc atgaattctc aggcggtcaa cgtcaacgta
    17401 tcggtattgc ccgtgccttg gtcatgcaac cagactttgt tattgcagat gagccaattt
    17461 cagccttgga cgtttctgta cgtgcccaag tcttgaactt gctcaaaaaa ttccaaaaag
    17521 agctcggcct gacctatctc ttcatcgccc atgacttgtc ggttgttcgc tttatttcag
    17581 atcgtatcgc agttatttac aagggtgtta ttgtagaggt tgcagaaaca gaagaattgt
    17641 ttaacaatcc aattcaccca tatactcaag ccttgctttc agcggtacca atcccagatc
    17701 caatcttgga acgtaagaag gtcttgaagg tttacgatcc aagtcaacac gactatgaga
    17761 ctgataagcc atctatggta gaaatccgtc caggtcacta tgtttgggcg aaccaagccg
    17821 aattggcacg ttatcaaaaa ggactaaact aataatggtt ttataatttc catgtcaatt
    17881 tttatgggaa ttataaaact ttttttgttg gactgatttg aaaaactttg aaagcttcct
    17941 gaaagaattt tcgaaaaatt ttaaaaaatt ttgaaatatt attgacaggt gatgaaaaag
    18001 gtggtaggat aggaaggatc aaaaaagaaa gcagaaaaag aaatgaataa gagacaagcc
    18061 gtaactatga atcaaaactt ttactttagc tactttagat agtgtttgta gacatgtcac
    18121 catggatgca aacagttcaa gcaatttgtt tgtatctatg tggctaagat ttttgattgt
    18181 ggtccatata gatgaatatc taaatggact agctaagttg taacttgtta ggttatttca
    18241 agtacccgtt tagatagtat ctaggcggtt ttttgtttta tcttttctga gaaggagttt
    18301 cattatgaaa gttgttcgaa aatcactagc cccctcttgg tagtggggat cctcttgact
    18361 tctctgatca gtttgcatca gttgaaggca gataagaaaa gagatgtctt tcgtatcggt
    18421 atttcgcagt ttattaccca ccagtcctta gacgctacta gagaaggatt tgtggatgag
    18481 ctggccaaac aaggctatgt tgagggggaa aatattgaga ttgatttgca aaatgcacag
    18541 ggagaacaaa gaaatctaaa aacgatttcc cagcaactag cagaatccag cgatgtcgtt
    18601 ctagccatcg caaggccttc tgctcagagc ttggccaata cgacgcaaac gacaccagtt
    18661 atcttttcag ctgtaacaga cccagtcagt gccaagttgg ttgagtcaag agaacatcct
    18721 gggggcaatg taactgggac aagcgatcag tcatcagatg ccatttcaac ccaaatcaat
    18781 ttgataaaga aagtgttgcc aaaggctaaa acgattggaa tcctctatac tcagagcgag
    18841 cccaattcgg ttgtttaaaa tgatgaagct aagcgacttc tgaaagaaaa aggctttacc
    18901 gttgttgaaa aaacaatctt ggacagtaat aacgtcaagg cggcagcaga gagtttgatg
    18961 gcagaggtgg atatggtttt tgtcccaact gataatatca tttcgtcaac catggaaaca
    19021 gttaagcagg tttctattaa acacaaggtt ccagtattcg gtggttcaac agaaatgatt
    19081 gctgttggtg acttgtataa ctacggaacc aattatgaag aattgggaag acagacagct
    19141 cgcatgctga ttcgtgtttt aaaaggtgag aaaccagaaa atatagcagt tgagttgcct
    19201 gaaaaactgg aattgcatac caatcaagaa atggcagatg cattgggaat tgatattagt
    19261 aagttagaag gcaaggaata aggaggatta agatgaattt tgtgttatct agtttatcag
    19321 aaggtttgtt gtggtcgatt gtggcgattg gggtctactt gactttccgt attttggata
    19381 ttgcggatat aactgctgag ggagcctttc ctctgggggc agcagtcgtt gtatcacaga
    19441 tacaggcagg ggcaaatcct tggcttgcga ctttacttgc tttgctggca ggtatggtag
    19501 caggtcttgt atcaggaatg ctccacacca agatgaaaat cccagctctc ttgacaggga
    19561 ttgtgacctt gacagggctc tattcaatca atattaaaat tatgggcagt gtacccaatc
    19621 tttccttggg agattctgca accgtcttta aacagttggc gagcttgggt ctgacaaatg
    19681 aaggagctgt tttctcactt agtttagtct gtctcttact tgtttggtct tgaccctttt
    19741 gatgaaaaca gagattggtt tggtcttgcg ttcgactggg gataatatcc cgataagtga
    19801 ggccaatgga gtcaatgtag acaccatgaa gattgttggt tacatgattt caaacggttt
    19861 gattgcccta tgtggttcct tgtttgccca aaatgatgga ttttcagatg tgacttctgg
    19921 gacaggaacc attgttgttg gtttgagctc ggaagtcttg atacacgact tgaccattgg
    19981 aggccgctta ttatccatcg gaatcggtgc tattgtttac cgtttgatta ttttaaatat
    20041 ctatgaaatt ccaaatctag atcaaaactt ggtacgtctc tttaatgcaa tcttgctcgc
    20101 tttggtttta tttgcaccag aattgcaaaa gagattaaag attcgtggtc tgaaattgag
    20161 aaatgaatag gaggagaaag ttatggcaag tttgttaaca cttgaaaata ttcacaagac
    20221 atttgaagca gggacggtca atgagaacca tgtcctcaaa ggattagatt tagaggttga
    20281 agagggagat tttatctatg tgattggtgg aaatggagca ggaaaatcca ctttgatgaa
    20341 tatcttggct ggcaatctat cggtggacga aggggacctt ctactggcag ggaaatccat
    20401 taaaaatctg agtgtcagaa agagagccaa ggatattgcc cgtgtttttc aatatcctaa
    20461 gatgggaaca gcttctcgtt tgacgattga ggagaatatg gctattgcct tgagacgtgg
    20521 gcaaaagaga gggcttggtt ggggtgtgaa ggagaaggat agaatccagt tccaagaggc
    20581 cttgaaggag ttgaatattg gtcttgaaaa ccgcttaaaa gtagatactc aatatctctc
    20641 aggaggacaa agacaggctt tgaccctagt catggcagct ctggtgaaac ccaaactttt
    20701 acttttggat gaacatactg cggcacttga cccgaaaacc agtcaaatgg tgatggactt
    20761 gacgcaaaag attgtggagc accattagtg gacgactttg atgattaccc atgatatgaa
    20821 tcatgcgatt gagtacggca atcgtctcat tatgctctat caaggcaaga tagtggtgga
    20881 tgtcaaggga gaagagaaaa agcatctgac agttgaagac cttatgcatc tcttccagaa
    20941 aaatagtggc caaagtctgg tcagtgatga attagttttg ggataaagaa aaaggctgag
    21001 atctggtgtc tcagtctttt atttcttgcg ttttgcaaaa tctacaaatc taaatttttc
    21061 taacttatgg cgactttcgg taaactgaaa ttggcgtccg tcttggagat agacttttga
    21121 tttaatcgaa acgacataag ggtctttgcc aatgtccatg agaatcttgt ctcggtcgct
    21181 tgagtggtca atggtgattt ccttctgagc ataatcaata aggagtttga ggccattttc
    21241 tatataagaa tagatagact gctcagcaat ttggcgagtg agatttggga tgagttccat
    21301 atccagatag tccgtatcca gaacggatac cagatcatcc accacacgct ggcggaccac
    21361 cttccaaacc atccgaaact ctgggaaacc ggttatcagt gaggattttt tatcaataat
    21421 aatcttgtcc agactgacca cgttggtttt agagcgcagt ccaagttctt taactagttc
    21481 ttggtagctg gttaggttgg atacagggaa attgacggtt tcttctttga cgacttgaga
    21541 accttgccct cttatctttt tgatcaatcc ttcctcttgg aggagagaca gggcctttcg
    21601 gacggtatca cgactcactt gatattgctc cataaggtcg tgctcgctag gaaggaaatc
    21661 tccgacagcg taagtctcgt tttgaatggt ttcttggatt tgcttaaata attgttggta
    21721 tttcttcatt ttgcctgctt taataggttt ttagtctagt ttaatgaaca cctgtatcta
    21781 ttttaccata caagtgctag aaaatttaca aaaaaacacc ctttttatac caaacaagtt
    21841 gcagacaagt ttggtatcgt ttacgatata cttatcaaat caaacttgct ttgacaagta
    21901 taaggagaat caaatgggaa aatttgaaca agaagccaaa gatctgcttc aggcaattgg
    21961 aggcaaagaa aatgtgactg ccgtaactca ctgtgcgaca cggatgcgct ttgttttagg
    22021 agatgataag aaggctaatg ttaaagctat cgagtcaatt ccagctgtta aaggaacttt
    22081 tacaaatgca ggtcaatttc aggtaatcat tggaaatgac gtgcccatct tttataatga
    22141 ttttacagcc gtttcaggta ttgagggtgt ttccaaagaa gcagccaagt ctgcagctaa
    22201 gagtaatcaa aacgtggtcc aacgtgttat gaccactctg gcggagattt ttactccgat
    22261 tattccagcc ttgatagtcg gaggattgat cctcggtttc cgtaatgtct tggaaggtgt
    22321 ccattggtcg atgttggatg gcaagaccat cacagaatcc tctcagtttt gggcaggtgt
    22381 caatcacttc ctatggttgc ctggtgaagc tatcttccag ttcttaccag tagggattac
    22441 ttggtctgtt tctcgtaaga tgggaaccag ccaaattttg ggaattgttc tcggaatctg
    22501 tttggtatcg cctcagttgc tcaatgccta tgcggttgct tcaacgccag cagctgatat
    22561 cgcggcaaac tgggtttgga attttggcta ttttactgtt aatcgtatcg gttaccaagc
    22621 ccaagttatc ccagccttgc ttgcaggttt gagtctgtct tatcttgaaa tcttctggcg
    22681 caagcatatc ccagaagtca tttctatgat ttttgtacct ttcttgtcat tgattccagc
    22741 cttgattttg gctcatactg ttttgggacc aatcggttgg acaattggac aaggactttc
    22801 atcagttgtc ttggcaggtt taactggtcc agttaaaggg ctcttcggtg caatttttgg
    22861 tgccctctac gctccatttg tcatcacagg tctgcaccat atgaccaatg ccattgatac
    22921 acaattgatt gcggatgctg gtggcactgc cctatggcca atgattgctc tttctaatat
    22981 tgctcaaggc tcagccgtgt ttgcctatta tttcatgcat cgccatgatg agcgtgaggc
    23041 tcaggtttca cttcctgcaa ccatttcagc ctatctcggt gttacagaac cagctctttt
    23101 tggggttaac gtaaaatata tttatccatt tgttgctggg atgactggtt cagcccttgc
    23161 aggcatgtta tccgttactt ttaatgtaac tgcggcttct attggtatcg gtggtttgcc
    23221 aggtattctc tctattcaac ctcaatacat gctgccattt gcaggaacta tgctagttgc
    23281 gattgttgtt ccaatgctct tgactttctt cttccgcaag gctggtctct ttacaaaaac
    23341 agagggcgat acgaacttgc aggcagaatt cgttgctcaa gaagaagcag aatttgtgaa
    23401 ccatgaacca gtagaactta cttcggtaga aattatcagc ccactaactg gccaagtgaa
    23461 agaattgagt caagcgacgg atcctatttt tgcatcaggt gtcatggggc aaggtctggt
    23521 cattgaacca agccaaggtg agttgacctc tccagttaat gggacagtga cggttctttt
    23581 ccctaccaag catgccatcg gcattgtctc tgacgaggga gttgaattgc tcatccacat
    23641 cggtatggat acagtaggtc ttgatggcaa aggttttgaa agtcttgtag tccaaggaga
    23701 tcacgttaca gttggtcagc aactgattcg ttttgatatg gatgtcatta aggctgcagg
    23761 tctggtgaca gaaactcctg ttatcatcac caaccaagat gcttatacag cgactattcc
    23821 cggaacttat ccgacaacga ttcaagctgg agcatctctc atggtcgcta cacgaatcta
    23881 atactcttcg aaaatctctt caaaccacgt cagctctatc tgcaacctca aaacagtgtt
    23941 ttgagcaacc tgtggctagc ttcctagttt gctctttgat tttcattgag tataattgaa
    24001 atagcacaaa tagggacgga agactgcttc ctccctttta tcagaaaagg agaaacagat
    24061 gacacttgat aaaggaaaag tagtctatca aatctatcca aaatcttaca aagacaccac
    24121 tggcaatggt attggggatt tccgtgggat tatcggaaaa attccctatc tagccaaact
    24181 aggtgtggat atggtctggc tcaatccatt ctatccaagt cctcaacggg ataatggtta
    24241 cgatatttca gattatatgg cagtggatcc tctttttggt gatatggctg attttgagga
    24301 aatggtgtgt atcggtaaag agcacaagat tgactttatg ctggacatgg tacttaatca
    24361 ttgttcgaca gagcatgaat ggtttcagaa agccctagct ggtgataagt attatcaaga
    24421 ctttttcttc atccaagacc aaccaacaga ttggcagtct aagtttggtg gttctgcatg
    24481 ggcgcctttc ggggatactg ggaaatacta tcttcaccta tttgatgaga cccaggctga
    24541 ccttaactgg cgcaatccca atgtccgtaa ggagcttttc aaggttgtta atttctggcg
    24601 cgacaagggt gtcaaaggtt ttcgatttga tgtgatcaat ttgattggta aggacgaggt
    24661 ttcagtggac tgtcctgaaa atgaagggaa gccagcttat acagacaaac ccatcgttca
    24721 taactatttg cgtatgatga accaagccac ttttggatct gacgatagct ttatgacagt
    24781 tggggaaatg tcttctacca ccatggaaaa ctgtgtcctc tattcgtcgc ctgatcgtca
    24841 ggaattatcc atgaccttta attttcatca cctcaaggtg gactataagg atggacaaaa
    24901 gtggaccttg gctccctttg attttgaaga gttgaagagt ctttaccata gttggggtaa
    24961 ggaaatgagt gataaagacg gttggagtgc cctcttttgg aacaatcacg atcaaccacg
    25021 ttccttgaac cgttttgtcg atattcaaaa cttccgcaag gaaggagcca ccatgctagc
    25081 agccagcatt cacctgtcac gtgggacacc ttatatctac atgggtgagg aaatcgggat
    25141 gattgaccca gactatgatt ctatggctga ttatgtggat gtcgaatcgc ttaatgccta
    25201 tcagatgctc ttagaagaag gaaagagtca gcaagaagcc ttccagatta ttcaagctaa
    25261 gtcgcgtgat aattcacgca ttcccatgca gtgggatgct tcggaaaatg caggattttc
    25321 aacaggcact ccttggttga aagctggtaa atcctataaa tacatcaatg tagaaaatga
    25381 aatccagggt ccgattttta ccttctatca agacttgatt cgactgcgta aggaaatgcc
    25441 aatcatttca gaaggaagtt acaaaccagc ctttgaagat agcaaacaag tctacgcttt
    25501 tgaacgccag tttgaggatc aaaagttact agtgctcaat aacttttatg ctaaagaagt
    25561 ggaaatcgac ttgccagcag tctaccaaaa tggacagatt ttgatatcaa actatgaaga
    25621 tgcagaagtg tctgagaaaa ttctactcaa accctatcaa acactggcta tttatgtaaa
    25681 ttaatactct tcgaaaatct cttcaaaccg tgtcagtttt atctgcaacc tcaaagcggt
    25741 gctttgagca acctgtggct agcttcctag tttgctcttt gattttcatt gagtataaac
    25801 ttagcaagga gacctctttt tcagaaaagc agcgttcttt ttgctgtcta ttccatccct
    25861 gaaagtgtag aacaaactgg tcagggtggc tagtttgtgg tataatgaaa gggattcaaa
    25921 aagaaacagg agaaaaatga tggatttact tttagcaatt gtattgattg tgctagcttt
    25981 tctaggagga gctcttggag gaatgtactt ggttcgtaag caaatcgaaa aagaatttgc
    26041 tgacaaccca cgtttgaatg ctgaagcagt tcgtactctt ttgagtgcaa atggtcaaaa
    26101 accaagcgaa gctaaggtac aacaagttta ccaccaaatc atccgccaac aaaaggcagc
    26161 ccttgctaac aataaaaaga aaaaataaat aaggaaaagt ctgggatgaa agttccagac
    26221 ttctcactat gttggttatg gtttagggat gagacttttt ccttgcattc tattgatatt
    26281 tgattatgat taagagagag gtagttgaca ttctatcaag ctgtcggtca gttcgttcag
    26341 tacaaggaat cataatgaac gatcaatcag aaaaaagact agaaagaaga ctgtatggat
    26401 aatcgaccaa ttggtttttt ggattcgggt gtcgggggct tgaccgttgt gcgcgagctc
    26461 atgcgccagc ttccccatga agaaatcgtc tatattggag attcggcgcg ggcgccctat
    26521 ggcccccgtc ctgctgagca aattcgtgaa tatacttggc agctggtcaa ctttctcttg
    26581 accaaggatg tcaaaatgat tgtcattgct tgtaacactg cgactgcggt cgtctgggaa
    26641 gaaatcaagg ctcaactaga tattcctgtc ttgggtgtaa ttttgccagg agcttcggca
    26701 gccatcaagt ccagtcaagg tgggaaaatc ggagtgattg gaacgcccat gacggtacaa
    26761 tcagacatat accgtcagaa aatccatgat ctggatcccg acttacaggt ggagagcttg
    26821 gcctgtccca agtttgctcc cttggttgag tcaggtgccc tgtcaaccag tgttaccaag
    26881 aaggtggtct atgaaaccct gcgtcccttg gttggaaagg tggatagcct gattttgggc
    26941 tgtactcatt atccactcct tcgccctatt atccaaaatg tgatggggcc aaaggttcag
    27001 ctcatcgata gtggggcaga gtgcgtacgg gatatctcag tcttactcaa ttattttgaa
    27061 atcaatcgtg gtcgcgatgc tggaccactc catcaccgtt tttacacaac agccagtagc
    27121 caaagttttg cacaaattgg tgaagaatgg ctggaaaaag agattcatgt ggagcatgta
    27181 gaattatgac aaataaaatt tatgaatata aggatgacca ggactggtat gttgggtctt
    27241 atagtatttt tggtggcgtt aacagtttga gcgactatca gacagatttt cctctgtttg
    27301 aattctccaa aatatttgga gatgaagagt atggtttccc gctttcagtt actgttttac
    27361 gctatggttc tacctaccgt ttgttctcct ttgtggtaga tatgcttaat caagaaatgg
    27421 gacgaaactt ggaagttatt caacgtcatg gggccctgct cttggttgaa aatgggcaac
    27481 tcttgtatgt agaattgcct aaagaagggg tcaatgttca tgatttcttt gagacaagca
    27541 aggtcagaga aaccttgttg attgcgactc gtaacgaagg taaaaccaag gaattccgag
    27601 ctatctttga taagttaggc tacgatgtgg aaaatcttaa tgactaccct gacctgcctg
    27661 aagtagcaga aacaggtatg acctttgagg aaaatgcccg ccttaaggca gaaaccattt
    27721 ctcaattaac gggcaagatg gttttggcag atgattctgg tctcaaagtc gatgtccttg
    27781 gtggcttacc aggcgtctgg tcagctcgtt tcgcaggtgt gggagcaact gatcgtgaaa
    27841 ataatgccaa actcttgcac gaattggcca tggtctttga actcaaggac cgctcggctc
    27901 agttccacac aaccctagtc gtagccagcc caaataagga aagtttagtt gttgaagcag
    27961 actggtcagg ttatattaac tttgaaccta agggtgaaaa tggctttggc tatgatcccc
    28021 tcttccttgt aggagagaca ggtgagtcat cagctgaatt aaccctggaa gaaaaaaata
    28081 gtcaatctca ccgtgcctta gccgttaaga aacttttgga ggtatttcca tcatggcaaa
    28141 gcaaaccatc attgtaatga gcgattccca tggcgatagc ttgattgtgg aagaagtccg
    28201 tgatcgctat gtgggcaaag tcgatgccgt ttttcataac ggcgattctg aactacgtcc
    28261 ggattctcca ctttgggagg gcatccgcgt tgttaaaggg aacatggact tctacgccgg
    28321 ctacccagaa cgtctggtga ctgagcttgg ttcgaccaag attatccaaa ctcatggtca
    28381 cttgtttgac atcaatttca actttcaaaa gttggactac tgggctcagg aggaagaggc
    28441 cgctatctgc ctctatggtc acttgcatgt gccaagtgct tggttggaag gcaagatcct
    28501 ctttctaaat ccaggctcta tcagtcaacc acgaggtacc atcagagaat gtctctatgc
    28561 tcgtgtggag attgatgata gttacttcaa agtggacttt ttgacacgag atcacgaggt
    28621 gtatccaggt ttgtccaagg agtttagccg atgattgcca aggagtttga gactttcttg
    28681 ttggggcagg aggaaacttt tttgacccct gctaaaaatc tagctgtgtt gattgatact
    28741 cacaatgcgg atcatgcgac cctcttgctc agtcagatga cctatacccg tgttcccgtt
    28801 gtgacagatg aaaaacagtt tgttgggacg attggactca gagatattat ggcttatcag
    28861 atggagcatg acttgagcca agaaatcatg gcggatacgg atatcgttca tatgacaaaa
    28921 acggacgtag cggttgtttc gcctgatttc accattacgg aggtcttgca caagctagta
    28981 gatgagtcct tcttaccggt tgtggatgca gagggtattt tccaagggat tattacgcgc
    29041 aagtccatcc tcaaggccgt taatgccctc ttgcatgact ttagtaagga atatgagatt
    29101 cgatgccaat gagagacagg atttcagcct ttttagagga aaagcagggc ttgtctgtca
    29161 attccaagca gtcctataag tatgatttgg agcaattttt agacatggta ggtgagcgga
    29221 tttctgagac cagtctcaag atttaccaag cccagctagc caatctaaaa atcagcgccc
    29281 agaagcgaaa gatttcggcc tgtaaccaat ttctatactt tctctatcaa aaaggagagg
    29341 tggacagctt ttaccgcttg gaattagcca aacaagctga aaagaagacg gaaaagccag
    29401 agattctata cctagactct ttttggcagg aaagcgacca tccagagggc cgcttgctag
    29461 cgctcttaat cctagaaatg gggctcttgc ccagtgagat tttagccatc aaggttgcgg
    29521 acatcaatct ggattttcag gtgttgcgaa tcagcaaggc ttcccaacgg aggattgtca
    29581 ccattcccac ggccttgctt tcagaattgg aacccttgat ggggcagacc tatctttttg
    29641 aaagaggagg gaaaccctat tctcgtcagt gggcctttcg tcagttagaa tcttttgtca
    29701 aggagaaagg ttttccatcc ttatcagctc aagtcttacg tgaacagttt attctaagac
    29761 aaatagaaaa caaggtcgat ttgtacgaaa ttgcaaaaaa attaggatta aaaacagtcc
    29821 tgaccttaga aaaatataga taatggatat taaattaaaa gattttgaag gacccctgga
    29881 cttactcttg catctggttt ctaagtacca gatggatatc tacgatgtgc ccattacgga
    29941 agtcatcgaa cagtatctag cctatgtctc aaccctgcag gccatgcgtc tggaagtgac
    30001 gggtgagtac atggtcatgg ctagtcagct catgctgatt aagagtcgta aactccttcc
    30061 gaaggtagca gaagtgacag acttgggaga tgacctggag caggacctcc tctctcaaat
    30121 cgaagaatat cgcaagttca agctcttggg tgagcacttg gaagccaagc accaagaacg
    30181 ggcccagtat tattccaaag cgccgacaga gttgatttac gaagatgcgg agcttgtgca
    30241 tgacaagacg accattgacc tctttttggc tttttcaaat atcctagcca agaaaaaaga
    30301 ggagtttgca caaaatcaca cgactatctt gcgggatgag tataagattg aggacatgat
    30361 gattattgtg aaagaatcct tgattggacg agatcaattg cgcttgcagg atttgttcaa
    30421 ggaagcccag aatgtccaag aggtcatcac cctctttttg gcaaccctag agttaatcaa
    30481 aacccaggag ctgatcctcg tgcaagagga gagttttgga gatatctatc tcatggaaaa
    30541 gaaggaagaa agtcaagtgc ctcaaagcta gacttgatag agaggaaaga tgagtacttt
    30601 agcaaaaata gaagcgctct tgtttgtagc gggtgaagat gggattcggg tccgccagtt
    30661 agctgaactc ctctctctgc caccgacagg catccagcaa agtttaggaa aattagccca
    30721 gaagtatgaa aaggacccag attccagttt ggctttgatt gagacaagtg gtgcttatag
    30781 attggtgacc aagcctcaat ttgcagagat tttgaaggaa tactctaagg cgcctatcaa
    30841 ccagagcttg tctcgggctg cccttgagac cttgtccatt attgcctaca aacagccgat
    30901 tacgcggata gaaattgatg ccatccgtgg ggttaactcg agtggagcct tggcaaagtt
    30961 gcaagctttt gacctgataa aggaagacgg gaaaaaggaa gtattggggc gccccaacct
    31021 ctatgtgact acggattatt tcctagatta catggggata aaccatttag aagaattacc
    31081 agtgattgat gagcttgaga ttcaagccca agaaagccaa ttatttggtg aaaggataga
    31141 agaagatgag aatcaataag tatattgccc acgcaggtgt ggccagtagg agaaaagcag
    31201 aagagctgat caagcaaggt ttggtgacgg ttaacggcca agtggtgcgt gaactagcaa
    31261 ccactatcaa gtcaggcgac aaggtcgaag ttgaaggtca acctatctac aacgaagaaa
    31321 aggtctatta tctgcttaac aaaccacgcg gtgtcatttc cagtgtaaca gatgacaagg
    31381 gtcgcaagac ggttgtcgac ctcttgccca atgtcaaaga acgtatttac cctgtgggtc
    31441 gtttggactg ggatacatcg ggtgtcttga ttttgaccaa tgatggggac tttacagacg
    31501 agatgattca ccctcgtaat gagattgaca aggtttatgt cgcgcgtgtt aaaggtgtgg
    31561 ccaataagga caatctccgc cccttgaccc gtggtcttga gattgatggt aagaaaacca
    31621 agccagctgt ttatgaaatt ctcaaagtgg acccagtcaa aaatcgctct gtggtgcagt
    31681 tgaccatcca tgaagggcgt aaccatcagg ttaaaaagat gtttgaagct gttggtctcc
    31741 aagtagataa gttgtctcgg actcgtttcg gacacctaga cttgacagga ctccatccag
    31801 gagaatcccg tcgtcttaat aaaaaagaaa tcagccaact acacaccatg gctgtaacta
    31861 agaaataatg aaacgaattt taatagcgcc tgtgcgcttt taccaacgtt ttatctcacc
    31921 agtctttcca ccctcttgtc gctttgagct gacttgttcc aactacatga ttcaggctat
    31981 tgaaaaacat ggttttaagg gggtattgat gggcttggct cggattttac gttgtcatcc
    32041 ctggtcgaaa acaggtaagg accccgttcc agaccacttt tcccttaaac gaaatcaaga
    32101 aggggaatga ggtggggtaa atagatttca aaatgataaa aacgcatcct atcaggtttg
    32161 agtaaacttg ataggatgcg ttttagaatg tcaaaatttt atactcttcg aaaatctctt
    32221 caaaccgctt cagctttcat ctgcaacctc aaaacagtgt tttgagcaac ctgcggctag
    32281 tttcctagtt tgctctttga ttttcattga gtattaaatt gagtttgaag tggcttattt
    32341 caaagctttt tgtatgtctt caatcatgag ttttgttgat tcaagtccgc ctccgcttag
    32401 ataccagagg tctggtgtta gttggataat cttaccattt ttagcagcag gtgtttcagc
    32461 gataagggca ttttctagga caccgtcgtt gctagagttg tccccaccga tggcaagggt
    32521 acggttgatg acaaagagga tgtcagggtt gatttctttg acactttcaa agctgacttc
    32581 ttgtccgtgg cgtgagtctt caaattttgt atcagttggt ttgaatttca aggtttggta
    32641 caagaaagag aaacgagatt tggcaccaaa ggctgccatt tttccttcat taaggaggat
    32701 cgcaagggct tttttgtcag agctttcatt tttagtagcg acttcttgga tgctcttgtc
    32761 tagcttggcc aattcttcct tggctttctg tgtaccagtt tcgccgaagg cacttgctaa
    32821 ggattcgata ttagccttgg tagaagtcca gtagtcgtcc ttgcttgctt ggaagagaac
    32881 ggttggggcg atttctttga atttgtctac gaatttttgt gtacgtggtg aagcgataat
    32941 caaatcaggc tcaagggcgg cgatagcttc taaatcaggt tctttcatag aaccaacatt
    33001 tttgacagtt cccactaggt cttttagata agtcggaaca gtttttgtag gcattccgac
    33061 gatatttttt tcaaatccta aagcgcgaat agtatccgca acgccgaggt caaaggtcac
    33121 aatcttttca ggaactttgg aaagtttgac ctcgtccagt gaacttttaa tggttacctc
    33181 tgttggagca gagctactgg tctctgtctg actagtgctt gagtttgtac tacatgcacc
    33241 aagtaggagc aagaagctgg ccactagggc agtgaaataa agtttaaggg atgttttcat
    33301 aatttctcct ttttaaaatg tgataacgat ttagggagtc tcttgatctt attgactaag
    33361 agactgaagg ttctctaact tgagctttta tgttactagc tatagataca gatctttttg
    33421 tcattgatat cagctagcgt gatgggaatc tcataaagtt gactgagtag gtcagcctgc
    33481 atgatttgat cggttcttcc cttgctaaag acctggccgt ccttgaaggc gacaatttca
    33541 tctgcatact gactggccat gttgatatcg tggaggacga tgataatggt cttgccgagt
    33601 tcctccacca gtcgtcgaag aatctgcatc atgctgacgc tttgcttgat atcgagattg
    33661 ttgagtggtt cgtccagcaa gataaagtcc gtatcctggg ccagtaccat agcgataaag
    33721 acgcgctgga gttgcccccc tgacaggcta ttgatgtagc ggtcttttaa gttggtcagt
    33781 tccaaatagt tcagagtttc tcggattttt tcccagtctt ctgatctaag tcgacctcgg
    33841 ctgtagggaa aacgtccaaa actgaccagt tcttcaacag tcaatttggc ttggtaattg
    33901 attttctgtt ttaggatggt tagttcttgg gccagttctt gcgaattcca gctctcgatt
    33961 tcacgtcctt tgatactgag aactccctga tctttcttgg ttagtctgct catgatggag
    34021 aggagagtcg attttccagc accatttgga ccaataaagg ctgtcagttt ttgaggactg
    34081 acttcaagcg aaatgccttg caaaatatcc tgtttttgaa tggatttgtc aatgttttcc
    34141 agtttcactg acgagacctc ctatatagta agataaagaa taagaagcca cccacactct
    34201 caatgatcat actgatacga atttccagtg caaagactcg ttcaatcaag gcttgcccca
    34261 aggttaaact aataaatcca atcagaatgg ccactataaa gagtaacttg tgctgatagt
    34321 ctttgacaat caggtaggtg aggttggcca gcataaagcc gaagaaggcc ataggtccta
    34381 ccaaggcagt ggccgttgag gtcaaaagca cgattcccca gaggagctct ttctgttctt
    34441 tttcaacatc gagtcccaat atctgagccg tttctctttg caggtgcaag acatctagaa
    34501 cgactgcttt tcgaaagaaa aagattgtca aagcgaggat gatcagagaa ccgatggcta
    34561 ggatggaagt gttgagatgt tgaaaggagg caaaaagact attttgcagt ttatcgtatt
    34621 cgtttggatc cattaggact tgaaggaagg tgctgatatt tcgaaagaga cttctgagcg
    34681 ctagacagat cagcaggatg aagaccaggt cttgcttcat cagtgtcttc aagtaacctt
    34741 gtaaggcgag aaagaagagg gactggacaa gaagtaagac taggaattct aagatagggg
    34801 atttgccaag ttgaagaaac ttgctttcaa aaaccagtag tagggtttgt agtaggacgt
    34861 agaaggattc aattcccaaa atactaggcg tcaggaagcg attttccgtc agggtttgaa
    34921 aactaatggt cgaaatccca gtcgcgatgg ctaccaagag ataaacgatg atcttttggg
    34981 aacgcaactt ccaagcaaag gctgacaagt gagtgatggg ccaaaagtag agaagacaag
    35041 ctccgatggc aagaataatg agaatccaga agagcttggt atgtttgctt ttagtctgca
    35101 tcttttcgtc cccctctcca gagaagtagg ataaagacga gactaccgat gattcctagc
    35161 aagagactga cagacaactc atagggccta atcagaactc gggataggat atcgcaagcc
    35221 agaactagat tggcaccaac cagtgcgacc atgagtttgg tttgacttag attatctcca
    35281 tagcacttgc gaacaagatt gggaacgata actccgagaa atggtaggcc acccacggta
    35341 atcatggtga cgcttgtcgt tagcgccacc agaaagaggg ccagtttttc aagtagggag
    35401 taggaaatcc ccaaactctc gctggtttct ttccctagat tcatgatggt gaaggtttgg
    35461 gataatttcc aaacggttat caggatgatg aggcctaaga agagccactc atactgatgg
    35521 gtctgaatca tggagaagga gccctgggtc caggcagtca tactctgaac cagattgaaa
    35581 cgataggcga taacttctgt gactgagccg ataatcccgc tatagatgat cccaatcaga
    35641 ggcaacatcc acctttcctt tacagtaaaa atggtcataa aggctaggaa gaagagggtg
    35701 aatacgatgg atgaaacaaa agcgaagagc atcttttggg tcagactagc cgatggaaag
    35761 acaaaaaggc tcagcaccat tcccagtttg gcggcttcag tcgttccaac tgtactcggt
    35821 gcagcaaact gattttgggt aatagtctgc atgagaaggc ctgccatact catactagag
    35881 gcagtcagga gaatactgat agttcttggg agacgggact cttgaaagag gagccaggtc
    35941 tgctggtcga aatcaaatag ctttccccat gaaaaatcac tggtcccaat gctaatagag
    36001 agaaagacta ggagtagaag taagccaatt aaataatgag aaagtttcat accccgtcct
    36061 ttcatgtaga tttggtatcg aaagatatct gcggatataa atgtaacatt atttttctaa
    36121 tctgtcaata aaatttctga caatttaata aatacaacaa ggagagagca acaagacttt
    36181 ctcctttgtt atcctattct aaaatgtttt taccttaatc tgataaaata atatcttcga
    36241 gggagtagct agccgtccaa tcaagatatt gtttagcttt tgaagcatct gctaggacac
    36301 tggctgggtc actagcacgt cgagcaacaa tctcgtgtgg gattttttaa tttagtaatt
    36361 cttcagcagt tttaaagatt tctttgatag tatagccttt tttagttcct aagttaaaga
    36421 tttgagaaga actgtcttct tgaaataggt agttcattcc tttaacatga gcctatgcaa
    36481 ggtccaagac ataaatgtaa tctcgaatac atgaaccgtc acgtgtatcg tagtcatctc
    36541 caaatatttt taagctatca ttttgtccca atgcggtctt gttgatattt ggaatgatgt
    36601 gagttggatt tttcacacgc agaccgtttg aagcatccat ttcagcccca gcaacattaa
    36661 agtaacggaa aataacatat ttccagtcgt agcgattggc catccagtaa atcattcgtt
    36721 cgcccatcag ttttgtctct gtataagggt tgacagggtc gatcagggta tcttcagtcg
    36781 ccggcttgtc aatacagtta tttccataga gagaagcagt cgaagagaac atgatttttt
    36841 gagtgccaac ttcagataag actttgagaa cttggttcct accagcaacg ttggcagtga
    36901 agtatttact tggattttca atactttcgc tcacaacaat ttcacctgca taatggagga
    36961 cagcatcaat ctgattttct tctaagtaag cctttaaggc gctagcatca taaacatcca
    37021 gttctttaaa gctagcacga ttatccacag tcgctcgatt tcctgtggag agattatcga
    37081 ggacatgcac cttataacca gcatttaaaa gagctttaac ggtatgggag ccaatgtagc
    37141 tagtcccacc tgtaacaaga attgttttgg tcatgatttt ttccttttct agttttgtac
    37201 tatagtaaat tgaaataaga tatgaacaac tctattagga aaggcaaatt aatt
//
LOCUS       DAVLUM010000008        37089 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLUM010000008 DAVLUM010000000
VERSION     DAVLUM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.008"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(7..1674)
                     /locus_tag="VYN42_000331"
     CDS             complement(7..1674)
                     /locus_tag="VYN42_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1461467.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(1677..2042)
                     /locus_tag="VYN42_000332"
     CDS             complement(1677..2042)
                     /locus_tag="VYN42_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1461468.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(2199..2387)
                     /locus_tag="VYN42_000333"
     CDS             complement(2199..2387)
                     /locus_tag="VYN42_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1461469.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(2650..2848)
                     /locus_tag="VYN42_000334"
                     /pseudo
     CDS             complement(2650..2848)
                     /locus_tag="VYN42_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(3103..4647)
                     /locus_tag="VYN42_000335"
     CDS             complement(3103..4647)
                     /locus_tag="VYN42_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1461470.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            4860..5162
                     /gene="gatC"
                     /locus_tag="VYN42_000336"
     CDS             4860..5162
                     /gene="gatC"
                     /locus_tag="VYN42_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1461471.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5162..6628
                     /gene="gatA"
                     /locus_tag="VYN42_000337"
     CDS             5162..6628
                     /gene="gatA"
                     /locus_tag="VYN42_000337"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1461472.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            6628..8070
                     /gene="gatB"
                     /locus_tag="VYN42_000338"
     CDS             6628..8070
                     /gene="gatB"
                     /locus_tag="VYN42_000338"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1461473.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISNEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            8199..8759
                     /gene="efp"
                     /locus_tag="VYN42_000339"
     CDS             8199..8759
                     /gene="efp"
                     /locus_tag="VYN42_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1461474.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            8781..9170
                     /locus_tag="VYN42_000340"
     CDS             8781..9170
                     /locus_tag="VYN42_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1461475.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            9163..9585
                     /gene="nusB"
                     /locus_tag="VYN42_000341"
     CDS             9163..9585
                     /gene="nusB"
                     /locus_tag="VYN42_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1461476.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(9634..9870)
                     /locus_tag="VYN42_000342"
     CDS             complement(9634..9870)
                     /locus_tag="VYN42_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1461477.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(9883..10334)
                     /locus_tag="VYN42_000343"
                     /pseudo
     CDS             complement(9883..10334)
                     /locus_tag="VYN42_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10352..10537)
                     /gene="briC"
                     /locus_tag="VYN42_000344"
     CDS             complement(10352..10537)
                     /gene="briC"
                     /locus_tag="VYN42_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1461478.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(10695..11462)
                     /locus_tag="VYN42_000345"
     CDS             complement(10695..11462)
                     /locus_tag="VYN42_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1461479.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(11459..12325)
                     /locus_tag="VYN42_000346"
     CDS             complement(11459..12325)
                     /locus_tag="VYN42_000346"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1461480.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(12362..13729)
                     /gene="accC"
                     /locus_tag="VYN42_000347"
     CDS             complement(12362..13729)
                     /gene="accC"
                     /locus_tag="VYN42_000347"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1461481.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(13741..14163)
                     /gene="fabZ"
                     /locus_tag="VYN42_000348"
     CDS             complement(13741..14163)
                     /gene="fabZ"
                     /locus_tag="VYN42_000348"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1461482.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(14160..14645)
                     /locus_tag="VYN42_000349"
     CDS             complement(14160..14645)
                     /locus_tag="VYN42_000349"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1461483.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(14648..15883)
                     /gene="fabF"
                     /locus_tag="VYN42_000350"
     CDS             complement(14648..15883)
                     /gene="fabF"
                     /locus_tag="VYN42_000350"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1461484.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(15905..16636)
                     /gene="fabG"
                     /locus_tag="VYN42_000351"
     CDS             complement(15905..16636)
                     /gene="fabG"
                     /locus_tag="VYN42_000351"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1461485.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(16670..17590)
                     /gene="fabD"
                     /locus_tag="VYN42_000352"
     CDS             complement(16670..17590)
                     /gene="fabD"
                     /locus_tag="VYN42_000352"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1461486.1"
                     /translation="MTKTAFLFAGQGAQCLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEATPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(17583..18557)
                     /gene="fabK"
                     /locus_tag="VYN42_000353"
     CDS             complement(17583..18557)
                     /gene="fabK"
                     /locus_tag="VYN42_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1461487.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(18676..18900)
                     /locus_tag="VYN42_000354"
     CDS             complement(18676..18900)
                     /locus_tag="VYN42_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1461488.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(18960..19934)
                     /locus_tag="VYN42_000355"
     CDS             complement(18960..19934)
                     /locus_tag="VYN42_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1461489.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(19934..20368)
                     /locus_tag="VYN42_000356"
     CDS             complement(19934..20368)
                     /locus_tag="VYN42_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1461490.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(20462..21247)
                     /locus_tag="VYN42_000357"
     CDS             complement(20462..21247)
                     /locus_tag="VYN42_000357"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1461491.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            21572..22936
                     /locus_tag="VYN42_000358"
     CDS             21572..22936
                     /locus_tag="VYN42_000358"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1461492.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            22939..23310
                     /locus_tag="VYN42_000359"
     CDS             22939..23310
                     /locus_tag="VYN42_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1461493.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            23523..24797
                     /gene="serS"
                     /locus_tag="VYN42_000360"
     CDS             23523..24797
                     /gene="serS"
                     /locus_tag="VYN42_000360"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1461494.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKDLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(24822..25721)
                     /locus_tag="VYN42_000361"
     CDS             complement(24822..25721)
                     /locus_tag="VYN42_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1461495.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(25831..26379)
                     /locus_tag="VYN42_000362"
     CDS             complement(25831..26379)
                     /locus_tag="VYN42_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1461496.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(26597..27919)
                     /locus_tag="VYN42_000363"
     CDS             complement(26597..27919)
                     /locus_tag="VYN42_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1461497.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(28010..28098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(28262..30598)
                     /locus_tag="VYN42_000364"
     CDS             complement(28262..30598)
                     /locus_tag="VYN42_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1461498.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGAALNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(30702..31250)
                     /locus_tag="VYN42_000365"
     CDS             complement(30702..31250)
                     /locus_tag="VYN42_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1461499.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEDQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(31247..31549)
                     /gene="zapA"
                     /locus_tag="VYN42_000366"
     CDS             complement(31247..31549)
                     /gene="zapA"
                     /locus_tag="VYN42_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1461500.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            31636..32508
                     /locus_tag="VYN42_000367"
     CDS             31636..32508
                     /locus_tag="VYN42_000367"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1461501.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            32520..33134
                     /gene="lepB"
                     /locus_tag="VYN42_000368"
     CDS             32520..33134
                     /gene="lepB"
                     /locus_tag="VYN42_000368"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1461502.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            33368..35734
                     /locus_tag="VYN42_000369"
     CDS             33368..35734
                     /locus_tag="VYN42_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1461503.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDAEFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASSHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDSNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(35782..37065)
                     /locus_tag="VYN42_000370"
     CDS             complement(35782..37065)
                     /locus_tag="VYN42_000370"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1461504.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEETYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        10725 a         8549 c         7210 g        10605 t
ORIGIN      
        1 ttaatcttat tccacactaa ataggtatgg gtaaacaggt tgttgacctt ggtgaatctc
       61 gacttcaacg tcttcgaatt cttctacgat ttcttgagcg atttcattgg caagttcttc
      121 gcttccgtct tcaccgacat agaaggttac gatttcactg tcttcatcca acatatgttt
      181 caaggtttca gtcaatgttt ggtgcatatc agggtttgac acaagaattt ttccatccac
      241 catacctaga ttatcgtttt catggatttc taagccatcg atcgttgtat cacgcacggc
      301 tgttgtgacg cttccgctaa cgacatcgct aagagcagct gtcatacgct cttgattttc
      361 ttcaatggac ttgcttggat caaaggcaag aagacttgtc ataccttgag gaagagtgcg
      421 agcctctacc actactgctg gttgctccaa aacttctgcc gcagattgag ctgccatgaa
      481 gatgttcttg ttgtttggca agaagatgat gttacgggca ttgacctgtt caacagcctt
      541 gataaagtct tctgttgaag ggttcatggt ttgaccgcct tcgataacat aatccacgcc
      601 ttgagaacag aagatatctg ctagaccttt accagccacc acagcaatca aagcatactc
      661 tttttcttca gccgacttga taacttgagt agcttctttc tcaacctgtg cttcgtgttg
      721 gttacgcata ttgtcaactt ttaccttgac caagctacca tatttgagac cttcttgcat
      781 aacaagtcct ggatcttctg tatgaacatg gactttgaca atttcatcat cgttaacaac
      841 gaggagagaa tccccaagct catccaagta gttacggaat tcatcgtagt caaaatcttt
      901 agcataagtt ggaccttgct taagagctac catgatttca gtacagtaac caaacgtgat
      961 gtcctcagtc gctacgtgac cagctacaga cttatgatgc tctacattga tcatctcact
     1021 catgttagca ggagtcgcta caaagtcctc agatgcaata tattcgccag taagggctga
     1081 aaggaaacct tcgtagatga agaccaatcc ttgaccacct gagtccacaa cgccaacttc
     1141 tttcaatact ggaagcatgt ctggtgtttt agctagagct gttttagcac cttccaaggc
     1201 tgcgcgcatg acttcaacag tgtcatctgt ttgctcagct tttttcttag caccgatagc
     1261 agctccacga gaaactgtca aaatcgttcc ttcaacaggt ttcatcactg ccttataggc
     1321 aacttccaca cctgattgga aggccagagc caagtcttga cctgttaact cgtctttatc
     1381 cttgatagct tgggaaaatc cacggaaaag ctgagatgta atcactcctg agttcccacg
     1441 cgcacccatc aaaagccctt tggcaagaat gctcgctact tctccaactg tagaagctgg
     1501 cttgtctgca acttctttag caccattttc aatggtcatt cccatatttg tcccagtatc
     1561 tccatctgga actggaaaga cgtttaatga attgacatat tcagcttgct tattcaagcg
     1621 agttgatgca gcctgcacca tttcttgaaa taagctagta gtaatttttg acacggttat
     1681 tctcctacaa ctttgatatt ttgaatgtag acatttacag tctgagcagt aattccaagc
     1741 tggttttcca agctaaaggc aacacgctct tgaatgtttt ttgacacttc actaatcttt
     1801 gttccgtagc ttaacacggt atatacatca actgcaatac tgccatcttc ggctgccttt
     1861 acgacgacac ctttagaata attttcctta cctagcaggg cttggaaatt atctttgagg
     1921 gcatttttac tagccatacc gaccacacca aaaatctcag ttgctgctcc acctacgacg
     1981 gttgcaatca cttcatctgt tagttcgatt tgaccatctt ttgtattaat ttttacagtc
     2041 atccttttta cctcaactag ttgatactct attttatcat atttcagccc aagtgtaaaa
     2101 gcagaatgat gtatcagcgg atatttactc tatttttcaa acgatgttat acccacaata
     2161 aaagaaaaaa gaccctaagg tctcctttgc ttttattatt aaacgcgttc aactttacct
     2221 gatttcaaag cacgagctga agcccaaact tttttaggtt taccatcgat aagaacagta
     2281 actttttgaa ggtttggttt tacggcacgt tttgtttggt tcatcgcgtg tgaacggttg
     2341 tttcctgata cagtcttacg acctgtaaag taacatactt tagccattgt gttttcctcc
     2401 tattagatct aatatagcgg atgtgctagc accacatacc gtactatgtt atcacacttt
     2461 cttgtttttt gcaagggaat tggaagattt tttatttgtg tcttaaatca ggtcttgcgt
     2521 gacattttct gctctccaca tgccattgtt gattaacaga acaccagaat taaaattatg
     2581 tgtataaaaa tcatcatatg aaagtccctc aaaggggaga cgataacctt tcagaatact
     2641 actgtcaatc taaacattca caatctcact attcaaagtc tctagtcttt tttccatcaa
     2701 ttggaaccat tctcgcggaa ggtcatcatt aaaaacataa aacttaagat tataatagat
     2761 gaacacaaag agattttatt gttatttcaa ctttatccat ataagcatta tctgcaccta
     2821 agacaatcgc ttttttctct tctttcactc tttatctcat ttctttttat tcccatcata
     2881 tgtttctacg taaccattat tttcgcccat tcgttcgtaa aaccatacca gtggagattt
     2941 tagatgaagt cccattacgg tttacaattt ttacattacg acacggagtt ttacaaatcg
     3001 atttcatttg ccaaacgtag ttagtaaggc agttagctag ttcgccaaat agcgactagc
     3061 gtccaacaat ttggaacttt agttccaatt gttggtactg agtcacatct tctcctctaa
     3121 ctctacgtct ggatacttgt ccgcaaacca gcggagggca aagtcatttt caaagagaaa
     3181 gactggttgg tcaaaacggt ctttggctaa gatattgcga cttgacgaca tccgttcatc
     3241 caagtcctca ggcttgatcc aacgaacggt ctttttaccc attgggttca taactacttc
     3301 tgcattgtac tcgccttcca tgcggtgttt aaagacttca aactggagtt gacctacagc
     3361 gcctagcatg tactcacctg tttggtaatt cttataaagc tgaatagcac cttcttgaac
     3421 caattgctca atccccttgt ggaaggattt ttgcttcata acattcttag cagaaacttt
     3481 catgaaaatt tcaggagtaa aggttggcag tggttcaaat tcaaacttgt ttttaccaac
     3541 tgtcaaggta tccccaactt gataagtacc ggtatcgtaa accccgataa tatcacctgc
     3601 cacggcattg atcacattct cacgactttc cgccataaac tgagtaacat tagacagttt
     3661 agccccctta ccagtacgag ggagattgac actcatgccg cgctcaaatt cgccagatac
     3721 gatacggaca aaggcaatac ggtcacggtg acgagggtcc atgttggctt ggattttaaa
     3781 gacaaatcct gagaaatcct tgtcataagg atccacaatt tcaccgtctg ttttcttgtg
     3841 accatgtggt tctggagcaa acttgaggaa ggtttcaagg aaggtctgca caccaaagtt
     3901 tgtcagggct gaaccgaaaa agacaggcgt caattctcca gccagaatag cttcctctga
     3961 aaactcattc ccggcttcat ttaaaagctc aatgtcatcc ttgacttgct cgtagaaagg
     4021 attgctacca aagagtttgt ccccgtcttc tagactggca aaacgctcat cccctttgta
     4081 aagctctaaa cgttggttat agaggtcata caagccctca aaggctttcc ccatcccgat
     4141 aggccagttc atagggtagc tagcaatgcc caagatttct tccaattctt gcaagagatc
     4201 caaaggctca cgaccgtcac ggtccagctt gttcataaag gtaaagactg gaatgccacg
     4261 atgtttcaca acctcaaaca atttcttggt ttgagcctcg atccccttgg cagagtccac
     4321 gaccatgacc gcagcatcca ccgccatcaa ggtacgatag gtatcttctg agaagtcctc
     4381 gtgccctggc gtgtctaaga tattcacgcg cttgccgtcg tagtcaaatt gcataacaga
     4441 tgaagtaaca gaaatcccac gttgcttctc gatatccatc cagtcagatt tagcaaaagt
     4501 ccctgttttc ttccctttta ccgtaccagc ctcacgaatc tcacccccaa agtagagtaa
     4561 ctgctcagtg atggttgttt tccccgcgtc cgggtgggag ataatggcaa aggtacgacg
     4621 tttcttaatt tcttcttgaa tattcataag ttctctttct ttgattctct atttttcttg
     4681 tttcaatagc tgagaatgat ttttacattg gattttacca ttcctttcaa cactccatta
     4741 tatcggattt tagcattttt ttcaatttct atttcttttc acttccccct cccttattta
     4801 taggaaaata tggtaaaata gaacagacta aaaatcatca tttcacgaaa ggatgcaaga
     4861 tgaaaattac gcaagaagag gtaacacacg ttgccaatct ttcaaaatta agattctctg
     4921 aagaagaaac tgctgccttt gcgaccacct tgtctaagat tgttgacatg gttgaattgc
     4981 tgggcgaagt tgacacaact ggtgtcgcac ctactacgac tatggctgac cgcaagactg
     5041 tactccgccc tgatgtggcc gaagaaggaa cagaccgtga tcgcttgttt aaaaacgtac
     5101 ctgaaaaaga caactactat atcaaggtgc cagctatcct agacgatgga ggagatgcct
     5161 aatgactttt aacaataaaa ctattgaaga gttgcacaat ctccttgtct ctaaggaaat
     5221 ttctgcaaca gaattgaccc aagcaacact tgaaaatatc aagtctcgtg aggaagccct
     5281 caattcattt gtcaccatcg ctgaggagca agctcttgtt caagctaaag ccattgatga
     5341 agctggaatt gatgctgaca atgtcctttc aggaattcca cttgctgtta aggataacat
     5401 ctctacagac ggtattctca caactgctgc ctcaaaaatg ctctacaact atgagccaat
     5461 ctttgatgcg acagctgttg ccaatgcaaa aaccaagggc atgattgtcg ttggaaagac
     5521 caacatggac gaatttgcta tgggtggttc aggtgaaact tcacactacg gagcaactaa
     5581 aaacgcttgg gaccacagca aggttcctgg tgggtcatca agtggttctg ccgcagctgt
     5641 agcctcagga caagttcgct tgtcacttgg ttctgatact ggtggttcca tccgccaacc
     5701 tgctgccttc aacggaatcg ttggtctcaa accaacctac ggaacagttt cacgtttcgg
     5761 tctcattgcc tttggtagct cattagacca gattggacct tttgctccta ctgttaagga
     5821 aaatgccctc ttgctcaacg ctattgccag cgaagatgct aaagactcta cttctgctcc
     5881 tgtccgcatc gccgacttta cttcaaaaat cggccaagac atcaagggta tgaaaatcgc
     5941 tttgcctaag gaatacctcg gtgaaggaat taacccagag gttaaggaaa ccattctaaa
     6001 tgccgctaaa cactttgaaa aattgggtgc tattgtcgaa gaagtcagcc ttcctcactc
     6061 taaatacgga gttgccgtat actacatcat cgcttcatca gaagcttcat caaacttgca
     6121 acgcttcgac ggtatccgtt acggctatcg cgcagaagat gcaaccaacc ttgatgaaat
     6181 ctatgtaaac agccgaagcc aaggttttgg tgaagaggta aaacgtcgta tcatgctggg
     6241 tactttcagt ctttcatcag gttactatga tgcctactac aaaaaggctg gtcaagtccg
     6301 taccctcatc attcaagatt tcgaaaaagt cttcgcggat tacgatttga ttttgggtcc
     6361 aactgctcca agtgttgcct atgacttgga ctcactcaac catgacccag ttgccatgta
     6421 cttggctgac ctcttgacca tacctgtaaa cttagcaggt ctccctggaa tttcgattcc
     6481 tgctggattc tctcaaggtc tacctgtcgg tctgcaattg attggtccca agtactctga
     6541 ggaaaccatt taccaagctg ctgctgcttt tgaagcaaca acagactacc acaaacaaca
     6601 acccgtgatt tttggaggtg acaactaatg aactttgaaa cagtcatcgg acttgaagtc
     6661 cacgtagagc tcaacaccaa ttcaaaaatc ttctcaccta cttctgccca ctttggaaat
     6721 gaccaaaatg ccaacactaa cgtgattgac tggtctttcc caggagttct accagttctc
     6781 aataaagggg ttgttgatgc cggtatcaag gctgctcttg ccctcaacat ggacatccac
     6841 aaaaagatgc actttgaccg caagaactac ttctatcctg ataaccccaa agcctaccaa
     6901 atttctcagt ttgatgagcc aatcggttat aacggctgga ttgaagtcga gctagaagac
     6961 ggtacgacca agaaaatcgg tatcgaacgt gcccacctag aggaagacgc tggtaaaaac
     7021 acccatggta cagatggcta ctcttatgtt gacctcaacc gccaaggggt tcccttgatt
     7081 gagattgtat ctgaggcaga tatgcgttct cctgaagaag cctatgctta tctgacagcc
     7141 ctcaaggaag ttatccagta cgctggcatt tctgacgtta agatggagga aggttcgatg
     7201 cgtgtggatg ccaacatctc ccttcgtcct tatggtcaag agaaattcgg taccaagact
     7261 gaattgaaga acctcaactc cttctcaaac gttcgcaagg ggcttgaata cgaagtccaa
     7321 cgtcaagctg aaatacttcg ctcaggtggt caaatccgcc aagaaacacg ccgttacgat
     7381 gaagctaaca aagcaaccat cctcatgcgt gtcaaggaag gggctgctga ctaccgctac
     7441 ttcccagaac cagacctgcc tctctttgaa atctcaaacg agtggattga ggaaatgcgg
     7501 actgagttgc cagagtttcc aaaagaacgt cgtgcgcgtt atgtatctga ccttggttta
     7561 tcagactacg atgctagtca gttgactgct aataaagtca cttctgactt ctttgaaaaa
     7621 gctgttgccc taggtggtga tgccaaacaa gtctctaact ggctccaagg ggaagtcgct
     7681 cagttcttga atactgaagg taaaacactg gaacaaatcg aattgacacc agaaaacttg
     7741 gttgaaatga ttgccatcat cgaagacggt actatttcat ctaagattgc caagaaagtc
     7801 tttgtccatc tagctaaaaa tggcggtggc gcgcgtgaat acgtggaaaa agcaggtatg
     7861 gttcaaattt cagatccagc tatcttgatc ccaatcatcc accaagtctt tgccgataac
     7921 gaagctgctg ttgccgactt caagtcaggc aaacgtaacg ccgacaaggc ctttacagga
     7981 ttccttatga aggcaaccaa aggccaagcc aacccacaag ttgcccttaa actacttgca
     8041 caggaattgg cgaagttgaa agaaaactag acagaacaaa accagcccta aggttggttt
     8101 tttcttctct cccaactccc aataactatt ttggctttat ttccagagta ttttatggta
     8161 aaatgaagag taataatatt tattaaagag gtaaaaacat gattgaagca agtaaattaa
     8221 aagctggtat gacctttgaa acagctgacg gcaaattgat tcgcgttttg gaagctagtc
     8281 accacaaacc aggtaaagga aacacgatca tgcgtatgaa attgcgtgat gtccgtactg
     8341 gttctacatt tgacacaagc taccgtccag aggaaaaatt tgaacaagct attatcgaga
     8401 ctgtcccagc tcaatacttg tacaaaatgg atgacacagc atacttcatg aatacagaaa
     8461 cttacgacca atacgaaatc cctgtagtca atgttgaaaa cgaattgctt tacatccttg
     8521 aaaactctga tgtgaaaatc caattctacg gaactgaagt gatcggtgtc accgttccta
     8581 ctactgttga gttgacagtt gctgaaactc aaccatctat caaaggtgct actgttacag
     8641 gttctggtaa accagcaacg atggaaactg gacttgtcgt aaacgttcca gacttcatcg
     8701 aagcaggaca aaaactcgtt atcaacactg cagaaggaac ttacgtttct cgtgcctaat
     8761 ctctagaaag aggtcattct atgggaattg aagaacaact tggcgaaatc gttatcgccc
     8821 cacgtgtact tgaaaaaatc attgctatcg ctactgcaaa ggtagagggt gttcactctt
     8881 tttcaaacag atcagtgtct gatacccttt caaaactttc actcggccgt ggcatttatc
     8941 ttaaaaacgt ggacgaagaa ctcacagcag atatctatct ctaccttgag tacggagtaa
     9001 aagttcctaa ggtagcggtt gctatccaga aagctgtcaa agatgccgtc cgtaatatgg
     9061 ctgatgtaga actcgctgct atcaatattc acgttgcagg tatcgtccca gataaaacac
     9121 caaaaccaga attgaaagat ctatttgacg aggacttcct caatgactag tccactatta
     9181 gaatctagac gccaactccg taaatgcgct tttcaagctc tcatgagcct tgagttcggt
     9241 acggatgtcg aaactgcttg tcgtttcgcc tatactcatg atcgtgaaga tacggatgta
     9301 caacttccag cctttttgat agacctcgtt tctggtgttc aagctaaaaa ggaagaacta
     9361 gataagcaaa tcactcagca tttaaaagca ggttggacca ttgaacgctt aacgctcgtg
     9421 gagagaaacc tccttcgctt gggagtcttt gaaatcactt catttgacac tcctcagctg
     9481 gttgctgtta atgaagctat cgagcttgca aaggacttct ccgatcaaaa atctgcccgt
     9541 tttatcaatg gactgctcag ccagtttgta acagaagaac aataaaaaga aaaagtgttt
     9601 gatatctatc aaacactttt tctttgcctc ccactatcta aaaaaatgat aatagatata
     9661 attgtaaaca aaaatccaga taggttttgc atgattgaga aagttaaaaa aactatggca
     9721 gagaatcgtt aatctcagat tgtcggtaga acgataaaca agggcaaaaa agaaaccaat
     9781 cagactataa tataataaac taattggatc tctgtgagat agtatcaaat ggctaatccc
     9841 aaagatgata gcagatagga taacatccaa ataatacttg gactagggaa agaaggtgtt
     9901 cataaaatac cctctatcaa gagtctcctc aaaaacagga ccgatgatta caggcaagac
     9961 aaaagataag atagtcgata aaaaggttgg ttgtccattt gaaagaacca cggtaaaata
    10021 ctcatcatga atattcctat gattaatcaa atgagcatag cgtgcccaaa aattaccgag
    10081 aatctgataa accacataag ttgcaaataa ggagaagaca aatgaccagt cccagctctt
    10141 tttctttttt aacctccaaa ttaatagaaa aggaaacttc ccactaatcc cactgttaaa
    10201 ataagagaat agacatcagc tcctaaccct aaaatgatcg tcacatacaa tccaattgtt
    10261 tgtggtaaat aggtagatag taaaataata agcaaaaata ttccaaattg tcttagtttc
    10321 tttgtgtttc tcatcgtact tttttgaaag attaccctgt tcggaagccg tacttccaag
    10381 catctatata agaattaagt gccccttgcc tcatataggg agcaaattct ctataatata
    10441 accatctact atatccatct tcccaaacag caagaccacc tgaagtttgc tccaagtcct
    10501 cagttgaaat aactgtaaat gtttctgtac ctgtcattgc aagtaccttc ttaaaataga
    10561 ttgttgtagg ctcacattta tagtatattt cttttttgtc tattttatag cccatctcct
    10621 caactatcaa tttttcaacc tgaattgcat ttttccataa aaaatgagac ctttctagtc
    10681 ccatttagtc attcttagta ttttctaaat cgttgatagc gttcttccag caactcttct
    10741 agcggttttt gtgaaagtct agccagctcc gtttggagtt cttttttgac actcttaatc
    10801 agttctttac tagaaagtcc tacttcagaa atcaccttat ccaccacgtc catttctaac
    10861 agttcatgcg aagtgatttt catcagttct gctgcttcca tggcgcgagt accgtccttc
    10921 cataaaatgg aagcaaagcc ttctggactg agaatggcat agatagaatt ttccagcatc
    10981 cagacacggt ccgcgacagc tagagccaga gccccgcctg aaccaccttc accgataata
    11041 atggcgataa taggaacttt caggtcactc atttccatga gattgcgagc gatagcttcc
    11101 ccttgaccac gttcttctgc tccgacacca ggataagcac ctgctgtatt aataaaggtc
    11161 acaactggac ggccaaattt ctcagcctgt ttcatcaacc gcagtgcctt tcggtagcct
    11221 tctggatgtg gttggccaaa attccgtttg aggttgtctt gcaaactctt gcctttttgg
    11281 ataccaacca ctgttacagc ttggtctcca agccaaccaa taccaccaac aactgcacca
    11341 tcatcacgaa aagaacggtc accatgtaat tggataaatt catcaaaaat gcctgtcgca
    11401 aagtccaagg ttgtcaagcg actctgctca cgcgcttctc tgactatttt tgcaatattc
    11461 atctaggact ccctccatgc aatctgacta ggctagcaat cgtatctggt aagtctcttc
    11521 ttttgacaat agcatccaca aagccatgtt ctaataggaa ttctgccttt tggaaatcct
    11581 caggcaagct ttcacgaacc gtattttcaa tcacacgacg cccagcaaaa ccaaccaagc
    11641 tctgtggttc agccagaatg atatcgcctt ccatagcgaa agaagctgtc acaccaccag
    11701 tcgttggatc tgtcaaaatg gtcaggtaaa agagaccagc atttgaatga cgtttaaccg
    11761 ccgcagagat cttagccatc tgcatgagac tcatgattcc ttcctgcata cgggctccac
    11821 cagaggctgt gaataggaca actggcaatt tttcgacagt cgcatactca aacaaacgag
    11881 tgattttttc acctacaacc gtacccatag aagccatgat aaagttagaa tccataatcc
    11941 caagagccac agtctgacct ttaataagag cagttcctgt cacaacggct tcatgcagac
    12001 ctgttttttc acgcatagat gccagtttct tttggtaacc agggaaatgc aagggatcct
    12061 tgctttcaat ccctgtaaac aattctttga aggttcccat atcaatcgtc aaagccaagc
    12121 gttcttgggc agaaatacga aaggtatagc tacagtgcgg acagatacgt tcacttccca
    12181 gatccttctg atagatggta tgcttacagc ctggacactg ggaaaataat tcatctggaa
    12241 cctctggctt agcttgaggt ttttccctaa ccgaacgatt gggattgatt cgaatatact
    12301 tatctttttt actaaataga gccattgatt ccccttttcg gtttaaactc ttaaagtcat
    12361 tttattcttt ttcttgatat ttaggtaaga aggtttccat caagaaggaa gtatcataat
    12421 ccccagcaat gacattgcga tctgaaatga ggtcaagctg gaaatctgca ttggtctgca
    12481 ctccttcaat ctctaattca tagagggcac gttgcatttt catcaaggcg tcaaaacgat
    12541 tttcgccgtg tactatgatt ttggcaatca tactatcata ataaggcgga atggtataac
    12601 ctggataaac tgctgaatcc acgcgcaagc caactccacc acttggcaga tagagattag
    12661 taatcttacc tggacttgga gcaaagttaa aggctgggtt ttctgcattg atacgacact
    12721 cgatggcatg accgcgtagg acaatatctt cttgcttaac agacaaaggc tgacctgccg
    12781 caatgcaaat ctgttcctta acgatatcaa cacctgaaac aaactctgtt actggatgtt
    12841 ctacctgaac acgagtattc atctccatga aatagaaatt gctacttgct tcatcaagaa
    12901 gaaattcaat ggttcctgca ttctcatagc caacaaactc tgccgctcga acagcagcag
    12961 cacctatttc atgacgcagc gtttttccga ttgcaatcga gggactttct tccaaaacct
    13021 tttggttatt cctttgaaga gaacaatccc gctcacccaa gtgaatcaca tgtccatgct
    13081 catcacctag gatttgaacc tcaatgtgcc gagctggata gataacccgt tctatgtaca
    13141 tggcaccatt gccataattg gccttggcct cactagaggc agtttcaaag gcagaaacga
    13201 ggtcatctgg tttttcaacc ttacgaatcc ctttaccacc tccacctgct gaagccttga
    13261 gcataacagg atagccaatt ttttcagcaa caatcaaagc ttcttcagag ttatgcactt
    13321 ctccatctga acctggtata acaggcacac ctgctttaat catctgagca cgcgcattga
    13381 tcttatcccc catcatatcc ataacatgac cagatggacc gataaacttg atacctactt
    13441 cttcacacat ggtcgcaaat ttggaatttt cactgagaaa tccaaaacca gggtgaatag
    13501 cttctgcctc agtcaagact gcagctgata gaactgcatt aatattgaga taagactctg
    13561 ttgccttgcc aggaccaata caaactgctt catctgccaa aagcgtatga agagcttcct
    13621 tatcagcagt tgaataaacc gctaccgtcg caatccccaa ttcacgtgcc gcacggataa
    13681 tacgaaccgc aatttcacca cgattggcaa ttaaaatttt tcgaaacatg gagaacctcc
    13741 ttagttccca attgcaaaag taaggatacc actggctgca agcttgccat ccacttcagc
    13801 ctttgcttca accacagcta tggtgccacg acgttttaca aaagtcgctg tcataaccaa
    13861 ttggtcgcct ggtacaactt gcttcttgaa cttaaccttg tccataccag cgtaaaagac
    13921 cagttttcct ttattttcag gttttgataa ctccaacaca ccagcagttt gcgccaaggc
    13981 ttccataatc agaacacctg gcataactgg gtattgagga aagtggccgt taaagaaagg
    14041 ttcgttaatg gtcacatttt tgatagcaac aatggtatcc tcgctcactt ccaagacacg
    14101 gtccactaga agcataggat aacggtgggg aagagcttct ttgattcctt gaatatcgat
    14161 catttgatac gtaccaatcc tttaccaaac tcaaccattt cttcgttaga gacgagaatt
    14221 tccgttacca caccatcctt aggagctggg atttcattca tgactttcat ggcttcgata
    14281 attaccaatg tttgaccttt tttgacacta tcaccaactg taacaaaggc aggtttatct
    14341 ggtccagcag ccaagtaaac cactccaaca agtggactct ctacaagatt tccctcagta
    14401 gccacacttg cttcagctgg agctggaact tcttctgcta cagtctctgc tggagcagat
    14461 gtaggagcta ctggactcgg tgttgctaga acgggtgctg gagcgacttg agttgcaact
    14521 tcaggcacag gtcttgcttc attcttgcta aactgcaact catccgtccc atttttataa
    14581 gaaaattctc tcaaacttga ctggtcaaat tgagtcatca agtctttaat atcgtttaaa
    14641 ttcatactta tctattctcc caacgtttga aagcaagaac tgcattgtgg cctccaaaac
    14701 caaaagtatt tgaaatagcg tatggaattt ctttctccaa gccttgtcca taaacgacat
    14761 tagcttcgat ataatctgat acttcacttg tcccagctgt cattggtaca aagttatggc
    14821 gcatagcttc gatggtgacg atagcttcta ctgcacccgc agcccccagc aaatgtcctg
    14881 taaaagactt ggttgatgat acaggtactt ccttaccaag aacagctacg atagctccac
    14941 tttctccttt ttcattggca ggagttgacg ttccgtgagc attgacatag gctacttgct
    15001 ctggagaaat ctcagcttct tccaaggcta gtttgatggc cttgatagct ccctgacctt
    15061 ctggatgtgg agaagtcatg tggtaggcat cacaagtatt tccgtaacca accacttcag
    15121 ccaggatagt agctccacgt ttttcagcgt gttcaagact ttctaaaacc aacatccctg
    15181 aaccttcacc cataacaaac ccattgcgat ccttatcaaa tgggatcgaa gcacgagttg
    15241 gatcctctgt agtagagaga gctgttaagg cttggaaacc agcgatggca aaaggtgtga
    15301 tagaagcttc tgttcctccc accaacatca catcttggaa accaaactta atggagcgga
    15361 aggcatcccc aatcgcatca tttgatgaag agcaggcagt attgatagat ttacaaacac
    15421 cgtttgcacc aaaacgcatg gctacattcc cagaagccat atttggtaaa gcttttggaa
    15481 gagtcattgg tttgacacgt ttgggtcctt tttcatgaag gcgaagtacc tgatcttcaa
    15541 tttccttgat tccaccaata ccagatgcaa cgataacacc aaaacgatcc ctattaagag
    15601 cctctacatc aagattggca tgatttacag cctcttgggc tgcatacaag gcatataaag
    15661 aatagttatc aaaacggttg gtatcttttt ttacaaagta tttatcgaac ggaaaatctt
    15721 ggatttctgc cgcattatgc acatcaaagt cactatgatc aaattttgta atgccaccaa
    15781 tgccgatttt cccagttgct aaactattcc aaaattcttc tggtgtattt ccgattggag
    15841 atgttactcc ataacctgtt accactactc gatttagttt cattcttttc acctctagct
    15901 ttcgctacat acttaagcca ccatcaatgg caatcacttg accagttaga taatcttggc
    15961 ctgctaaaaa tactgtcaaa tctgcaacct gctctgcctg cccaaattct ttcatcggaa
    16021 tctgagctag tgtagcttcc ttaatcttat ctgataagat agcggtcata tcagactcaa
    16081 tcattcctgg agcaatcaca ttgactcgta tattccgact agcgacctcg cgtgccacag
    16141 acttggtaaa gccaatcaag ccagccttag aagcagcata gttagcttga ccaatattcc
    16201 ccatcaaacc aacaacacta gacatattaa tgatagcacc ttctctggct ttcatcatcg
    16261 gtttcaagac tgattgtgtc atattaaagg caccagtcag attgaccttg agcacttttt
    16321 caaaatctgc ttctgtcatc ttgagcataa gagtatcttg ggtaatccct gcattgttga
    16381 ccaaaacatc tactgaaccc agttctgcaa tagcttgatc aatcatacgc ttagcgtctg
    16441 caaaatctga tacatctcct gaaatgggaa ccaccttgat accatagttt gaaaactcag
    16501 cgagcaattc ttctgagatt gccccacgac tgtttaagac aatgttggct cctgcttgag
    16561 caaacttgtg ggcgatggca agaccaattc cacgactcga acctgtaata aagatatttt
    16621 tatgttctag tttcattttt ttcctttcaa aacttctact tattttagtc tatttttcta
    16681 aaagtgctac taaactcgct tgatcttcca catgagctaa gtgagcagtt tgatcaattt
    16741 ttttaacaaa acctgacaag actttccccg gtccaatctc gataaagttg cttatgcctg
    16801 cttcttgcat gaccccaata ctttcataga aacgaacggg ttccttgacc tgacgcgtca
    16861 agagctgagc aatgtcctct ttttgcatca cagcagcttc tgtattgccg actaggggac
    16921 aagtaaaatc tgaaaaactt acctgagcta gagtttcagc tagtttctgg ctagctggct
    16981 caaggagagc ggtgtgaaag ggacctgaca ccttaagagg aatcaagcgt ttggcacctg
    17041 cttcttgcaa aagttcaacc gctcgatcaa ctgcaaccac ttctccagca atgacgattt
    17101 gtgcaggtgt gttatagttg gctggagtaa ccactccaag ttcagaagct ttttgacagg
    17161 cttcttcaat gacctctact ggcgtattga gaactgctac catcttgcca gagtcagcag
    17221 gagtcgcttc ttccatatag gctccacgct tagctaccaa ggcaaccgca tcttcaaaat
    17281 ccaaggcgcc gcttgccacc aaggcagagt attctccaag agacaaacca gcaaccatat
    17341 caggctgata gcccttttct tgcaataaac ggtagatagc aaccgaagtc gctagaatgg
    17401 ctggttgcgt atagcgggtc tgattgagtt tgtcctcttc cgtatcgatg agataacgca
    17461 aatcataacc gagcacctga ctcgctcgat caatcgtttc tttaacaatc ggatactgat
    17521 catagaaatc ccgtcccatc cctagacact gggcaccttg accagcaaat aaaaaggctg
    17581 ttttagtcat ttcttacaac tcctgtccag cgagaggctt cttcttgaat tttcttagcg
    17641 gctccgtaat acaaatcttt taggatttct tcagctgttt cttctttaga aacaagccct
    17701 gcgatttgac ctgccatgac agagccacca tccacatcac cgtgaacaac tgctttggct
    17761 agggcacctg ctcccatttg ttcaaagatt tctaaatcag gatcttcctg cttaaaggca
    17821 tctttttcag ccagttcaaa atctctagtc aactgatttt taatagcacg aacagcatga
    17881 ccaaagtgct gagctgaaat cgtagtgtca atatcccttg cttttaaaat tttctccttg
    17941 tagtttggat gggcattcga ctcttttgca actacaaacc gtgtccccac ctgtacagcc
    18001 tctgcaccta gcataaagcc agccgcagca ccttcaccat ccgcaattcc tcctgcagca
    18061 ataacaggaa tagatatagc tgtggctacc tgtcgcacca aggtcatggt tgttaatttg
    18121 ccgatatgcc ccccagcttc cattccttct gcaataacag cgtctgcacc gattttttcc
    18181 atgcgtttag ctaaagcgac actaggaaca acaggaataa cgattatccc agcttcatgg
    18241 aaacgttcca tatacttgct tggatttcct gctcctgttg tgacaacttt aacaccttct
    18301 tcaataacga gatccacgat atcttccaca aagggagata agagcatgat gttgacccca
    18361 aagggtttat cagtcaatga tttgatttta tcaatattgg ccttgacaac ttctttcggg
    18421 gcatttcccc caccgataat tcctaatcct ccagccttgg aaacagcccc tgccaaatca
    18481 ccatcagcaa cccaggccat ccctccttgg aaaataggat agtcaatctt caataattct
    18541 gtaatacgcg ttttcatagt gcctccaacc ttccttgctt acgtaatagt tcgatttcac
    18601 cataatttga cagtcaaact attacctaaa caagagggag tgggtttctc cctactcctt
    18661 ctactaatat tctgcttatt ttgcttgctc ttcaacgtaa gcaaccaagt caccaactgt
    18721 tttcaagtca ttttctgctt cgatttggat atcaaaagca tcttcgattt ctgagattac
    18781 ttggaacaag tccaatgaat ctgcgtccaa atcatcaaaa gttgattcaa gtgttacttc
    18841 tgatgcgtct tttccaagtt cttcaacgat aatttcttgt actttttcaa atactgccat
    18901 gataggactc ctttaaaata aatagttttt ttataacaat gtgttcacca catgattacc
    18961 taaattgtaa gaatgagcgt gccccaggtc aagcctccac cgaagcctga tagaagaaca
    19021 gtctggctac catctaaagg gatgagacct tgttctacac actctgaaag taaaatcggg
    19081 atactggctg cactggtatt gccatattcc atcatattgg ctggaagttt ggctcggtca
    19141 acaccaattt ttctagccat cttatccaaa atacggtcat tggcttgatg aagtagcaga
    19201 taatccaagt ctgtcacctc tataggagat tcatcaatag tctgcttgat agacttggct
    19261 acatctcgaa tggcaaaatc aaagactgtg cgtccatcca tcttcaaaaa cgaatctgca
    19321 ctttcttgat ctgaaaatgg agaatgcaaa cctgaatgcc cataagttaa acactcgctg
    19381 cgacttccat cgctattgag actctcagct aagaaatgct cttgctcgct agcttctaac
    19441 aagacaccac cagcaccatc tccaaacaac acagctgttg atcgatccga ccaatcgact
    19501 gccttagaga gggtttcact accaatcacc aagccttttt gaaagcgacc agaagcgata
    19561 aacttttcag cagttgaaag agcaaataca aatccactgc aagccgcggt taagtcaaaa
    19621 gcaaaggctt tattagcgcc aatattagct tgaacacgag cagctgtaga gggcatcatc
    19681 gaatctggag taatggtagc taggatgata aaatccagtt cttctcctgt tattccagct
    19741 tttgccatca gtttcttagc aacctctgta gccaaatcac tggtagattc tgttcttgaa
    19801 atatgccttt gtcgtattcc cgttcgactt gaaatccact catcattggt atccataatc
    19861 tgagccaagt cgtgatttgt aaccacttgc tctggcacat aatgagcaac ctgacttatt
    19921 tttgcaaaag ccattatttc aaatcctcca aaaattggta aagattagtc aagcctttac
    19981 ccatgacagc aatttcttcc tcgctcatgc catcaataat tttttctacc atggccttgt
    20041 ggaagcgttt atgcagtcta tgaatcaagc gacccttctt tgtcaaatgc agatgcacca
    20101 cacgacgatc ctgttctgac cgaactcgct caatgtagcc cttacgctct aaattgttca
    20161 aacttgtcgt aacagttcca agagttacca tcaactcttt tgacacttga cttggagtca
    20221 catctggagc cttaccgatg acatcaatcg tatgcatttc tttgatggag atatccttaa
    20281 aacgactacc tctcaagttc acttcctcaa ttacaaggac attgttaaat atagatgtta
    20341 aatattcatt gattcgttgg tagtccattt ttcatatccc tccttcttca aaaaactttt
    20401 acaatcaaaa catttgacag aaagaattat atcaaaattc aaagaatgat gcaagtattt
    20461 tttattttcc tgtaaattta ggtcttcttc tctccgaatg agctcgcact ccttctttga
    20521 aatcctctgt ttgagctaag gatttctgta ggttcagttc taaagtagcg taaccctgcc
    20581 agtctttaaa ttggctctcc caaaccaact tcttaatggc agcataggaa ttacttgaag
    20641 cacgtcttaa ttttttaaga agctgttctc tcgtcttttc aagtttttca gcttcagaaa
    20701 cgcggtaaac caacccccat tctagggctt tttctgccgt taaagcctct cctgtcatag
    20761 ctaattgagc agcacgcgtc acaccgatac tgcggctcaa gagatgaatt ccccctgcat
    20821 ctggagccaa accaacacca acaaaggctt ggataaactt agccttatcc gtcgccaaac
    20881 agaaatctgc cgcaacagcc atattcgctg cggcacctgc aacagcaccg tcaacttcca
    20941 ttaaaacagg tttggctatt tgcttgattt tataagaaat cgtattgacc aactctgcga
    21001 tttttgtcaa tgatggaata tcatcctcat ccactgcccg cttcatctct accaaatctc
    21061 ccccaactga gaagaccttt ccattggcat tgattaagat aaaatgcaca gctggatttt
    21121 cttctgccaa agtcagagct tctaaaatct cctcacacat gggaatatga aaaccatttg
    21181 cgacctcagg acggttcaag gtaaggattg ccaagtcctc ttcaagctga taaataatgt
    21241 gttccatcag ggctcctttt tattttataa gcagtttata ctcttcgaaa atctcttcaa
    21301 accgcgtcag cttccatctg caacctcaaa acagtatttt gagctgactt cgtctagctt
    21361 cttagtttgc tctttgattt ttattgagtg ttaaattatt tcactgtcaa agtatatctt
    21421 ttttaggatc agaaagcaag aaaaaatcga ctgaaagtgt ctcagccgat aagaaaggct
    21481 cgctttaggc tagaaagcat cttattttct tcattgaaaa aagcctttct ttctgctata
    21541 atcgtataaa atacttactt taggagttct tatgaaagtt gttaaatttg gaggtagttc
    21601 tcttgcctct gctagtcaat tagaaaaagt tttaaacatc gtcaaaagcg attcagagcg
    21661 tcgttttgta gtcgtttctg cgcctggtaa acgcaatgct gaagatacta aggttacgga
    21721 tgccctgatt aaatactacc gcgactatgt tgcgggtaac gatattagca agagccaaag
    21781 ctggattatc gaccgctatg ctgctatggt tagtgaattg ggactaaaac cagctgtgct
    21841 agaaaaaatt tctaaaagca ttcacgcctt ggccactctt cctattgaag aaaatgaatt
    21901 tctctacgat actttcctag cagccggtga aaataacaat gccaaattga ttgctgccta
    21961 ctttaaccaa aatggtatcg atgcacgcta tatgcaccct agagaagctg ggattgtggt
    22021 cacaagtgaa cctggtcacg ctcgcatcat tccatcaagt tatgacaaga ttgaagaatt
    22081 gacaaacacc aatgaagtcc ttgtcattcc tggtttcttt ggtgtcacta aggaaaatca
    22141 aatctgtact ttctcacgtg gaggatctga tattacaggt tctatcattg ctgctggtgt
    22201 caaagccgac ctctatgaaa actttacgga cgttgatggt atctttgcag cccaccctgg
    22261 tattatccac caaccacact cgattcctga gttgacctac cgtgaaatgc gcgagttggc
    22321 ctatgcaggc ttctcagtcc ttcatgacga ggctcttctt cctgcctacc gtggaaaaat
    22381 tcctctggtt atcaagaata ccaacaaccc tgaccatcca ggtactcgta tcgttctaaa
    22441 acacagtaat gatgaatttc cagttgtggg aattgctggt gactcaggct ttgtcagcat
    22501 taacatgtcg aaatacctca tgaaccgtga ggttggattt ggccgcaagg ttctgcaaat
    22561 cctggaagaa cttaacatcg gttgggaaca tatgccaaca ggtatcgacg atctttctat
    22621 cattctccgt tctcgccaac taactcccat caaggaagaa gaaatcctgc gtcagttggt
    22681 tcaaaaggct aaagtagatc atgcagaaat cgaacacgac ctttctatca ttatgattgt
    22741 tggtgaaaaa atgaagagcc acatcggagt gactgctact gcgacacgcg ctctatctga
    22801 aaacaaaatc aacatccaga tgatgtctca aggttctagt gaagtttcta ttatgtttgt
    22861 tgtcaataaa gaccaagaga aagcagcaat taaagccctc tacaatgcct tttttggaga
    22921 aagtaaggaa gactaagcat ggcccaatca cttaacaaaa cagtactcct cagtacgaca
    22981 ggcacttcct acctctctat cgctgggaaa gttgggaaat tccttgtcgg agatcaggct
    23041 ttggaatttt acccagatgt caatgtcgaa caatttatcc agattccttg gagccatatc
    23101 aatcagattg gagccaatgt cactggacgc aaaatcagcc gccacttcga agtctttaca
    23161 gacaaaggaa aattcctctt tgcttcaaaa gactcaggtg ccattctcaa aattgcacgc
    23221 gaaaaactag gcaatgacaa ggtcgtcaaa cttccgaccc tgattcagac aattagccaa
    23281 aaatttaaaa atctatttgc aaaaaagtag aaactttagt ataatcatag caacggataa
    23341 gtaggttatc ttcttctttc agaaagtctg agggtgctgc gagcagatag gagggatagg
    23401 tgaaattcta ccgttagtga caattacata cacaatcaag tgcacacctg tgaagttgga
    23461 tggaaccgtg gccctgccac tccaacgttt tgtcagggtg cttttttcat aaaggagttc
    23521 ttatgttaga tatcaaacgt attcgtacag attttgaagc tgtcgcagaa aaattagcta
    23581 cacgtggtgt agatgctgct gtcttgaatg aaatgaaaga aatcgatgct aaacgtcgta
    23641 acatcttggt caaggttgaa actctcaaag cagaacgtaa cacagtttct gctgagattg
    23701 cccaagctaa gcgcaacaag gaaaatacag atgacaagat tgctgccatg caaaatctat
    23761 ctgctgaggt taaagccttg gatgctgaat tggcagaaat cgatgctaaa ttgacagaat
    23821 ttacaacgac tcttccaaat atcccagctg acagcgttcc tgttggggct gacgaagacg
    23881 acaatgtgga agttcgccgt tggggtactc cacgcgagtt tgacttcgaa cctaaagctc
    23941 actgggatct cggtgaagac cttggtatcc ttgactggga acgcggtggt aaggtaacag
    24001 gcgctcgctt cctcttctat aaagacctcg gtgctcgttt ggaacgtgct atctacaact
    24061 ttatgttgga tgaacatgga aaagaaggct atactgaagt catcacacct tacatagtca
    24121 accatgattc tatgtttggt actggtcagt atccaaaatt taaggaagat acttttgaac
    24181 tcagcgatac caactttgtc ttgattccaa ctgctgaagt tcctctgaca aactactacc
    24241 gtgatgaaat cttagacggc aaagatcttc caatctactt cactgctatg agtccgtcat
    24301 tccgttctga ggctggttct gccggtcgtg atacgcgtgg cttgatccgt ttgcaccaat
    24361 tccacaaggt tgaaatggtc aaatttgcca aaccagaaga atcttacgaa gaattggaaa
    24421 aaatgacagc caacgctgaa aacattcttc aaaaactcaa ccttccatac cgtgtcgttg
    24481 ctctctctac tggagatatg ggcttctcag ctacgaagac ttacgacttg gaagtgtgga
    24541 ttccagcaca aaacaattac cgtgaaatct caagctgttc aaacacagaa gatttccaag
    24601 cccgtcgtgc ccaaatccgt taccgtgatg aagcagatgg caaggtgaaa ctccttcata
    24661 ccttgaacgg ttctggactt gcagttggac gtacagtggc tgcaattctt gaaaattacc
    24721 aaaatgaaga tggttctgtg accatcccag aagcacttcg tccatacatg ggtggagctg
    24781 aagtcatcaa accataaaaa ataaggttta gctatttcta gctagacctt ttttcgtaac
    24841 caaatcagat aagcacctag tacaaagaat aaaatagtta ggcatataat ggtttcagtc
    24901 aataccaggt aatccagaaa tggaagtttc aaaattccct gagccatctt gagcgaggtc
    24961 gctgtgataa tggttgggaa ggtgagggct gagaaggctg gttgaaaacc ttgttttaaa
    25021 atgttgggca gacgagttaa aacaaagaaa aagaaggatt gagaagccaa aatcatgaca
    25081 atcaagaccc aagtcggcag gctggttcct cctactcgaa ctagagaagc caagagtaga
    25141 gagaaaggag cacagtagat tccttcttgt ccaagcaagg ctagtgggag tggatgtttc
    25201 tttaaatcgc tataaataag gggatagaga tagaaggtca agagaaaacc aaaactcaag
    25261 gtcgcatagg caatttcgat aatacctacc agaggatagg tcaaggcagc cactgctatc
    25321 cccacataga gaaccgtcca gcttggagtg gcatgaaccc tccgccctgg acaagcaaac
    25381 ttgatggtaa aaccagcaat caaggtcaaa tccaagagaa atgaaaacca ccaaatccct
    25441 tgtgctacca aaggaagata agagaatacg cgaaagacat aggtcgataa aatcatccca
    25501 gccataggaa aggttgccat tcctgacaaa agagggggct tggtcaattc ttgcttggtt
    25561 tctttccaat taaagagatg cagaattaga aagtaaatcc ataaaaccaa accagtcaga
    25621 ctaaaaagat gggatagaac cggcaacgta tctaaaataa gatttccagc tcctgccaaa
    25681 cctagcaaac aacctgaaaa tactaagggg agttttttca tcctaacctc caataatcat
    25741 gttagtttca gtataacata aaagcgctta aatgaggatt taaaaaaacg aagtccgctt
    25801 atttcagact tcattttact cagatatgaa ttaggcataa ggttgcaatt ctggattaat
    25861 tggtgtatta gctaagttgt tggcatagtt acagaggatt gctaggctga caccaaaaac
    25921 cacatccaag gcattttgtt gagtgtagcc agcttctaaa aactcagaca aggcttcatc
    25981 tcctacacga cccttggtat tgataactgc caaggtaaac ttagctaggg tatccaattt
    26041 aggatctgtt tcaattggag tacgattgcg aagagcttga atcaagtcat cattcatctg
    26101 gatttgtttg atggaaaagg ctgtgtgacc tgcgacacag aatgcacaac cattggtcac
    26161 ggctgccgtg atttgcacca cttcacgctc aacgggtgtc aggctgttgc gacggtggat
    26221 agatgagaca atttggtagg cttctaaaac agtcggggca ttggccaaga gaccgattag
    26281 gttgggaata tagccattgt tgtctttttc tactgtttca agaatttctt tcacttctgc
    26341 tggtgctgac tctactgtat ggatagtaaa tgttgtcata agatacctct tttcttatta
    26401 ttgacactaa tattattgaa aaatcttata aaatcctgat tcctaagttt atctaagata
    26461 aagctttatt ctctcataag attttcgttg ttatattagt ttatcacact tccaatcact
    26521 tgcataatat atattatata tcaggctgat aaaaattatt tatagccaaa aaaatcacac
    26581 gagctgtgtg attccattat ttgtcaaaat actttttagt ttcagcaata acgactggcg
    26641 acaagaccaa gagggcaatc aagtttggca gagccatcaa ggcgttaacg atatctgcga
    26701 taatccagac catatccaac tcgataaatc ctcctaacaa gaccatgagc acaaaaacca
    26761 cacggtagag ccagataaag cgaaccccaa agaggaactc aaaacagcgt tctccgtaat
    26821 agttccaacc tagaatcgtt gtaaaggcaa aaagtacaag gaagatggtc aagagggcag
    26881 gcccaaagtg tgaaaagact gttgagaaag ctgactgagt caaggcaacc ccattcaagt
    26941 caccactcca aactccagtt accaagatgg tcaaaccagt tagagtacaa atgatgaggg
    27001 tatcaataaa ggttcctgtc atggaaatca aaccttgctc tactggttca tttgtcttgg
    27061 cagctgcagc tgcaatagga gcagaaccca gaccagattc gtttgagaac acaccacgcg
    27121 ccacaccatt ttgaatagcc atccgaacgc tagcaccagc aaatccacct accgcagcaa
    27181 ggggactaaa agctgaggta aagactaaag cgattgtacc agggattttt ccgatattaa
    27241 agaaaataac tgtaagagtt cctaagatat aaatgatggt cataaaagga acaacagtag
    27301 ttgaaacctt agaaatagac ttgagtccac caaagactgc aatcgctaca aagacagaca
    27361 agacgagagc tgtgatggct ggcgaaatcg tcgttgtatt ttggatagat tctgcaatcg
    27421 agttgacttg ggtgaaggtt ccgattccca agagagcaac caatactcct gctactgcaa
    27481 acaaaacagc aagtggtcgc cacttttctc ccatccctag aaggatatag tgcatgggac
    27541 ctcccgctac tgcaccatgg tcgtccttgg tgcggtattt gatggccaag agtccttccg
    27601 catacttggt agccattcca aagaaagccg ccatccacat ccaaaataga gctcctggtc
    27661 caccaacctt gatagccgtc gcaactccta tgatatttcc tgttccaaca gttgatgcca
    27721 aggctgtaca cagagctgca aaactggata catcaccatg tcccttatcc tggataaaaa
    27781 taagctgaaa ggccttgggc agacgcaaaa cctgcaagag tcctagccgc atggttaggt
    27841 aaatccctgt tccgaccaat aaaatcaaga ggggcggtcc ccaagcaaaa tcatcgattg
    27901 atttaagcaa ttctaacatt tccttctcct atcgtttcaa ccccaaaaga aagagcacat
    27961 gcaagataca tgtactctgg aatgcttaga taaatgctaa aaagcggtct atcctagctc
    28021 tgtcctttta cctgagagtt tgagcagttg cctgccttgc cccttcggtg cctttacggt
    28081 ctctccagag ttccgtccat ttacagtcat ggaaaatcaa acgattcccc acttctatta
    28141 aacttcattc ggtgttggta tttaattgat tctaatttta caaaaaatgt tggcttttgt
    28201 caatgtgttt attagtaaaa attagttcaa cagtttttac tttataaagt ccagaatact
    28261 gctatccttt aaaagtgaca atagtcgcac cactgcctcc agcattttgt ggggcatagc
    28321 cgaaactctt gacatgtttg tttctttgca agtatttggt aactccttca cggatgactc
    28381 ctgttccgat accatggatg atatcaactt gagccatatt gttaagcaag gcttggtcga
    28441 tgaaggtatc tagctcattc atggcttctt catagcgctt gcctcgaaga tccagtctag
    28501 cttgaggtcc tcgcccagaa gttcgtttta caacattgac ctgtttcttc ttgactggtt
    28561 tttcttgctg ggcttgaaca agatcaaact ctttctcttc caaggtcatc ttaatcaagc
    28621 caacttgggc ttcccagcgg ccgtccttga gttgactggt caaggtacca cgctgaccat
    28681 aactgagaac cacgatatca tctcccacct ttggagctcg ttttttcttg gccttttgaa
    28741 ggaccttgtt tttagacaag tccacttttt caggagccaa ttttttcaac ttggccttgg
    28801 cttcaatgat ttcgtggggc ttgagttgag atttactgtg gagatttttg agaatctggt
    28861 cactttcact tagggccata tccacaatct cagcagcctg ttcacgcgcc ttgttaagct
    28921 cggtttcctt ttcacgatta agctcgttgt agagtttttt tagcgcacgg ttcatcttga
    28981 gattttcttg ctccacctca cggatattgt ccaagcgttt gcggctttcc agcgtctgct
    29041 cttctaattg ctcaatgata cgattgacgt cattgtcctg atcgatctgc tgactagcat
    29101 ctcctacgat aacttcagat aggcctagac gtttggcaat ttcaaaggca ttacttcggc
    29161 caggaacacc ctgcataaag cgataggtcg ggcgaagagt tgcagtatca aactccatac
    29221 tggcattttg cacaaaggct gtctcaatac cgtaggcctt gagttctgga tagtgggtcg
    29281 tcgccatggt cttgatttga cgcaggcgaa ggtcctccag aatagccatg gcaagggctg
    29341 ctccctcttg gggatcagta ccagccccca actcatccaa aagtaagagt gaatgttggt
    29401 tgaccttgcc aagaatatcc acgatattgg tcatatggct agagaaggta gacaagctct
    29461 gctcaataga ctgctcatct ccaatatcag caaagatttc ttcaaaaata ccaacacgac
    29521 ttcccttgtc tgctaaaatc ggcaatcctg actgggccat gacctgtgtc aagcccagag
    29581 ttttgagcat gatggtcttc ccacctgtat tgggacctgt aatgacaata gctgttaaat
    29641 cttgaccaaa atagacatca tttgcgacgg catttttgac caaaggatgg cagacatgga
    29701 gcagttgaat ctcttgattt tctgacagct gaggcacgac tgcttgtctt tcttggataa
    29761 atcgaacctt ggcacgaatc aagtccagat gaccgataat ccaagcgtca ttagcaatct
    29821 cagccgcatg agggcggaca cgctcagaaa tttcttggag aatgcgaagc atttcatagc
    29881 gctcatctgc tcgcagacta gcaatttctt cgctcagttt gactacctca cgtggttcga
    29941 tatagacggt gtttccacta gcagaaatat catgaacgac acctgcaatc ttattgcggt
    30001 aggtgttttt gactggtaaa acctgacggc catttctgct agcaacaatt ccttccgtca
    30061 acatctgcgc tttttgcttg agtaagtctt gtaaaacatc gcgtacctga ctctcgctat
    30121 catgtatttt tcgacggatt cgcgccaatt cttcactggc aaaattttca atgaaacccg
    30181 catcattaaa ggcctgaaga tttccttgta attgcggaaa atcatgtaat ttctcaaacc
    30241 aaagggctaa ttcttccaaa ctgacatttt ccagattggc gtaaaaactt tgaagttctc
    30301 ggctggcaag aagcacgcgt ttcaagagta ggaactcctc gatattgaga gccgctccca
    30361 tctccaacct cttgcagact cctgcaattt ccttagttga gagaatagta aaatgcggtt
    30421 gctcgacgaa aagagcctgc atttccttca tctcagcaaa agcctgtttg attttatctg
    30481 ctttggcagt cggagccagt tgtctcaatt gctccaagcc ctgctcggtc aacaaatgag
    30541 gctcaaacaa ggccttgacc ttatcgaact ctaatgtttc taatattttc ttattcatct
    30601 ttatttcctt gtctttgaat gtctaggtgt ggtagctttt tacattctga tagattcgag
    30661 tcaaatctgt aaacaaaggg ctaggaaaac tcctgccctt tttatccgat taaatttgtc
    30721 acccagattt gtttgagcca actggttgtt atcggtatgc tctggatgat gtgttttgcg
    30781 acgatactct tttcaagagg attttgtata actgccatgg ggatggtcgc caagattgtc
    30841 aaggccattt gcaagacaaa taaggtcacc aacatggaca agatacctgc tgaaacttgg
    30901 aacaacttac cacccagttt tttgctagga atcaagtgta agagaagacc aagcaaacga
    30961 ccaatgctat agacaatccc aaatacaagc aagtagccga tacctgcata aaagacctta
    31021 tccagctgaa agagttgatc cgatgggaaa aagaaagtcc cctgatcttc ctgcgaattt
    31081 gcataaggga gcaataaatg gaattgctct ccaagcccct tataaaactg gccagccata
    31141 aaagccgatg ccatggctga aatcaggtaa taaacctgta agagcaggcc tctccgatag
    31201 ccgatataaa atccccaaac caagaccaat agaagaagga atgaaatcat aaggaatcct
    31261 caatcttgct ctgttcttgc ttacaagtca caagcttgtg acggagttct tctagctctt
    31321 gctccttatc gtcaaattca atctcacggc tgagctgagt tgataaacag ttgactgcca
    31381 acaaaagagc gattgtttca tcatctgcgc taggcatttg ttctttaatt gcttggtatt
    31441 tttctgtcgc aaccttagcg atttcctcca taaaaaggtt atcatgttcg cttgtcaagg
    31501 ttaacgattt tttcccgaat gtaaatttga atcgatttag atttgccata aaattcacct
    31561 cacgatatta taccaaaatt cgctaatttt gtcagttttt acaaatttta ctgcttttgt
    31621 ggtacaatag aaactatggc aagtatcaca ctcacaccaa gcgaaaagga tattcaggct
    31681 tttcttgaac actatcaaac cagtctggct cctagcaaga atccctatat ccgctacttt
    31741 ttgaaactac ctcaagcaac ggtttctatc tatacttctg gaaaaatctt gcttcagggt
    31801 gaaggggctg aaaaatacgc cagtttcttt ggctatcaag ctgtagagca aaccagcgga
    31861 caaaatcttc ctttaattgg gacagatgag gtgggaaatg gttcctactt tggtgggctt
    31921 gcagttgtgg ctgcctttgt cacacctgac cagcacgact ttttacgaaa actcggtgtg
    31981 ggggattcta agactctgac cgaccaaaag atccgtcaga ttgctcctat tctcaaggaa
    32041 aaaatccagc accaggcact ccttctctca cccagcaagt acaacgaggt catcggagac
    32101 cgctacaatg ctgtttcggt taaggttgcc ctccataatc aggctatcta tctcctcctt
    32161 caaaaaggtg ttcagcctga gaaaattgtg attgatgcct ttaccagtgc taaaaattat
    32221 gacaagtact tggcacaaga gaccaatcgt ttcagcaatc ctatcagctt agaagaaaag
    32281 gctgagggca aatacttggc tgtcgcagtt tcttctgtca ttgcgcgtga tctctttctg
    32341 gaaaatcttg aaaatctggg acgagaactg ggttatcagc ttccaagtgg agctggaacg
    32401 gcttctgaca aggtggctag ccagattttg caagcctatg gtatgcaggg actcaacttc
    32461 tgcgctaagc tacactttaa aaatactgaa aaagcgaaaa acgcttagaa aggtaagtta
    32521 tgaatttatt taaaaatttc ttaaaagagt ggggattatt cctcctgatt ctgtcattac
    32581 tagctttgag ccgtatcttt ttttggagca atgttcgcgt agaaggacat tccatggatc
    32641 cgaccctagc ggatggtgaa atcctctttg ttgttaagca cctccctatt gaccgttttg
    32701 atatcgtggt ggcccatgag gaagatggca ataaggacat cgtcaagcgc gtgattggaa
    32761 tgcctggcga caccattcgt tacgaaaatg ataaactcta catcaatgac aaagaaacgg
    32821 acgagcctta tctagcagac tatatcaaac gcttcaagga tgacaaactc caaagcactt
    32881 actcaggcaa gggctttgaa ggaaataaag gaactttctt tagaagtatc gctcaaaaag
    32941 cccaagcctt cacagttgat gtcaactaca acaccaactt tagctttact gttccagaag
    33001 gagaatacct tctcctcgga gatgaccgct tggtttcgag cgacagccgc cacgtaggta
    33061 ccttcaaagc aaaagatatc acaggggaag ctaaattccg cttctggcca atcacccgta
    33121 tcggaacatt ttaagaaacc taagaggccg agaatcacca atctcagcct cttcttctat
    33181 cgtgagaagt gattgtttat tgacaaatac tcaatgaaaa tcaaagaaca aactaggaag
    33241 ctagccgtag gctgcttaaa acagtgtttt gaggttgcag atggaagctg acgtggtttg
    33301 aagatatttt cgaagagtat aaaataaaaa caatcccaac tctcacctat tcatacaaag
    33361 gaattttatg gaagtttatt tttcaggaac cattgaacgg attatttttg aaaatcccag
    33421 caatttttat cgcatcctcc tcctagaaat cgacgatacg gacgcagagg attttgatga
    33481 ttttgaaatc attgtcacag gaaccatggc tgatgtaatt gagggcgaag actatacttt
    33541 ttgggggcaa attgtccagc actccaagta tggagaacaa ctgcaaatca gtcgttatga
    33601 tcgcgcaaaa ccaactagta agggcttggt caagtacttt tcaagtagcc atttcaaggg
    33661 gattggtctc aagacagctc agaaaatcgt ggatacctat ggcgaaaata ccattgacga
    33721 aattttgcaa cacccagaaa agttagaagg catcgcagga ctctctgcca aaaatcgcga
    33781 ggctttcgtc tccactctcc gtctcaacta cggtacggag atggttttgg ccaaactagc
    33841 caactacggc attcccaaca aactagcctt tcagattcaa gacttttaca aggaagaaac
    33901 ccttgatgtg gttgaaaatt atccctacca gctggttgag gatatcaagg gtttgggctt
    33961 taccattgct gaccaactag ctgaggaact aggcatcgaa agtcaggctc ctgaacgctt
    34021 ccgcgccggt ctagttcaca gtctttttca ggcctgtatg gaaacagggg acacctatgt
    34081 tgaagcacgg gatttgctgg aacaaaccct tactctcctt gagtcttccc gtcccgtgga
    34141 actagacccc agccaagttg cccaagagct ctcctacctg atcgaagaag acaaggttca
    34201 gcagattgat accaagatct ttgacaacag cctctttttc gctgaggaag gtatccgcag
    34261 tcacttgatt cgtatccttg aaaaaggaga acagaagaga caagatttag aaactattca
    34321 aaagcatatc actactgtcg agcaagaact ggggattgag tatgataaca ttcaaaaaca
    34381 agctatttgt gacgctatcc agaacaaggt ctttatcctg acaggtgggc ctggtactgg
    34441 taagacaact gttatcaatg gaatcatcgc tgtttatgcc cttttagaag gacttgactt
    34501 caggaagaaa agcaatctgc ccattcttct tgctgctcca actggtcgag ctgctcgtcg
    34561 catgaatgaa ttgacaggtt tgcctagcgc gaccatacat cgccacttgg gaatgacagg
    34621 tgacgatgat accagtcatc tggaagatta cctagatgct gagtttatca tcgtggatga
    34681 attctctatg gtagatactt ggctggccaa tcaactcttc tccaatatct cttctaacag
    34741 taagatcctc atcgtaggtg acagtgatca gctaccttct gtcagtcctg gacaggttct
    34801 agcggatctg cttcatattc ctttgattcc tcagactcgc ttggaaaaaa tttatcgaca
    34861 aagcaaagaa tcaaccatcg tcaccctagc tagtcagatt cgacagggca tcttgccagc
    34921 tgatttcacc caaaaaaaag ctgaccgttc ctactttgaa attgctagta gccatattcc
    34981 tgccaccatt gaaaaaatct taggtgccgc cctcagaaat ggtattcccg cccgtgatat
    35041 ccaagttctg gctcctatgt accgagggac ggcagggatt gatgctatca atcagctcat
    35101 gcaagacctg ctcaatcccc cacaaaaaga tcaactcagt tttgaagctc ctcagtgtca
    35161 ctatcgtaag agagacaagg tcattcattt ggttaacgat gctgaaatca atgtctttaa
    35221 tggggattta ggagctatca cagacctgat tcctggtaaa tacaccgaat cgaaacaaga
    35281 cgagattgtc attgattttg atagtaatga agtctcttac ccccgtaacg aatggtacaa
    35341 gattcgcttg gcctatgcca tgagtattca taagtctcag ggaagtgagt tcccagttgt
    35401 catcctaccg attactagtg ctagccgacg tatgctggag cgaaatctca tctacacagc
    35461 cattacacgt gccaaaagca aactcatctt actaggcgaa ttacaagcct tcgactatgc
    35521 tacccaacac atcggaactg cccgaaaaac ctatctgatt gaacgcttca gtgatctact
    35581 ggagaatgtt gaagaaaagc aacaagctgt ctctgaaaca gtcacatcaa gtgcctctga
    35641 acaatcctac atcctaaccg aagaaaactg ggaccgcatc ccagccatga ttgggattac
    35701 agacacagac ctcaaagaga tttttggaaa atagtgcatc agaaaaccca ccaattcagg
    35761 tgggttttct gtttattaag attattttac tgttgctgtg cttgtgatca attcaacagc
    35821 ttttttgata gtgatatcat gtttcaacat gtcagctgaa agcaagtttt gaacttgtgc
    35881 aacttccatg ttgtagtctg ctgccaattg ctcaacttct ttttgtattt cttcttctga
    35941 agcatcaaat ccttcagctt tggcaactgc ttcgataaca aggttagtct tagtacgtga
    36001 ctcagcttct gcttggtatt ggttgtgaag gtcttcttga gtagttccag tgatttggaa
    36061 gtacatgtca gggttgatcc cttgacgttg caagttccca aggaattcat ttactgaacg
    36121 gtgaacttct tcatggatca tttcttctgg aagttctacg atttcagcgt tttctacagc
    36181 tgtatcaatt gctgcacctt caactgcatc tttgtaagtt tcttctttag cagcagccaa
    36241 ttctttgcgg tatttttctt tcaagtcagc aagtgtttca acttcttcat caatgtcttt
    36301 tgcaagttca tcgtcaagag ctggaacttc tttagctttt acttcgtgga tagttgtcac
    36361 gaatttagct tctttacctg caaggtcttc tgcttggtag tcttctggga atgttacgat
    36421 aacatcaacg gtttcgccag ctgagtgacc taccaattgg tcttcgaaac cagggatgaa
    36481 ttgacctgaa ccaagtccaa gtgagaagtt ttcacctttt ccaccgtcaa attcaacacc
    36541 gtcgatagaa ccaacgaagt cgatcacaac agtgtcgccg ttttcagcag cagcttcctt
    36601 gataaccaat tcagccaggt tgttgcgttc gcgttcgata cgctcttcga catcagcgtc
    36661 agttacttct ttttctacat caactgatac ttcaaggttt ttgtagtcac ccaattttac
    36721 ttcaggtttt gtaacgactt cagcagtgat aacccagtct tgaccttttt ccattgaagt
    36781 tacgtcaatt tttggttggg caaccacttc aagaccagct tcttttacag ctgcttcata
    36841 agcgtttggc aaaagtgcgt tcattgcatc ttgataaaga gcttcttcac caaatttttg
    36901 gtcgaagata ggtcgtggaa ggtgaccttt acggaaacct ggaacattaa gagatttctt
    36961 cactgacttg aagacacggt ccaattctgg tttgatttgg tcttgagaga tagtgaaagt
    37021 caagacacca cggtttgttt ctttgttttc aaatgataca gacattctgt catttctcct
    37081 taaaatttt
//
LOCUS       DAVLUM010000009        36805 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLUM010000009 DAVLUM010000000
VERSION     DAVLUM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.009"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            296..1360
                     /gene="pepA"
                     /locus_tag="VYN42_000371"
     CDS             296..1360
                     /gene="pepA"
                     /locus_tag="VYN42_000371"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1461505.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQSLVKKLDRSTVDLIKHY"
     gene            1382..1678
                     /locus_tag="VYN42_000372"
     CDS             1382..1678
                     /locus_tag="VYN42_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1461506.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            2360..2803
                     /locus_tag="VYN42_000373"
     CDS             2360..2803
                     /locus_tag="VYN42_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1461507.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            2807..3571
                     /locus_tag="VYN42_000374"
     CDS             2807..3571
                     /locus_tag="VYN42_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1461508.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFREDENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            3586..4314
                     /locus_tag="VYN42_000375"
     CDS             3586..4314
                     /locus_tag="VYN42_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461509.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            4307..5827
                     /locus_tag="VYN42_000376"
     CDS             4307..5827
                     /locus_tag="VYN42_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1461510.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            6172..6978
                     /locus_tag="VYN42_000377"
     CDS             6172..6978
                     /locus_tag="VYN42_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1461511.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(7144..7680)
                     /locus_tag="VYN42_000378"
     CDS             complement(7144..7680)
                     /locus_tag="VYN42_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1461512.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            7813..8703
                     /locus_tag="VYN42_000379"
     CDS             7813..8703
                     /locus_tag="VYN42_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1461513.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            8947..9300
                     /locus_tag="VYN42_000380"
     CDS             8947..9300
                     /locus_tag="VYN42_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1461514.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            9301..10338
                     /locus_tag="VYN42_000381"
     CDS             9301..10338
                     /locus_tag="VYN42_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1461515.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKVVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(10384..11391)
                     /gene="galR"
                     /locus_tag="VYN42_000382"
     CDS             complement(10384..11391)
                     /gene="galR"
                     /locus_tag="VYN42_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1461516.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            11555..12733
                     /locus_tag="VYN42_000383"
     CDS             11555..12733
                     /locus_tag="VYN42_000383"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1461517.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKREDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALYIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            12752..14233
                     /locus_tag="VYN42_000384"
     CDS             12752..14233
                     /locus_tag="VYN42_000384"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1461518.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGETVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            14303..14707
                     /locus_tag="VYN42_000385"
     CDS             14303..14707
                     /locus_tag="VYN42_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1461519.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            14888..15652
                     /locus_tag="VYN42_000386"
                     /pseudo
     CDS             14888..15652
                     /locus_tag="VYN42_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            15649..16110
                     /locus_tag="VYN42_000387"
     CDS             15649..16110
                     /locus_tag="VYN42_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HEV1461520.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDASIYE"
     gene            complement(16161..17423)
                     /locus_tag="VYN42_000388"
     CDS             complement(16161..17423)
                     /locus_tag="VYN42_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1461521.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSSAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSKGIVVASLLAIVLNAVLNHKKK"
     gene            complement(17423..18004)
                     /locus_tag="VYN42_000389"
     CDS             complement(17423..18004)
                     /locus_tag="VYN42_000389"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1461522.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(18405..18500)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(18884..19012)
                     /locus_tag="VYN42_000390"
     CDS             complement(18884..19012)
                     /locus_tag="VYN42_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV1461523.1"
                     /translation="MKANYPIYRPLTKRKFRVSDHYIYPHEFAVLDPNGYFLRFSE"
     gene            complement(19123..19266)
                     /locus_tag="VYN42_000391"
     CDS             complement(19123..19266)
                     /locus_tag="VYN42_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1461524.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(19278..20105)
                     /gene="xth"
                     /locus_tag="VYN42_000392"
     CDS             complement(19278..20105)
                     /gene="xth"
                     /locus_tag="VYN42_000392"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1461525.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            20239..20694
                     /locus_tag="VYN42_000393"
                     /pseudo
     CDS             20239..20694
                     /locus_tag="VYN42_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            20847..21221
                     /locus_tag="VYN42_000394"
     CDS             20847..21221
                     /locus_tag="VYN42_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1461526.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKP
                     GVLYSSKISSNRVNVALPYVGY"
     gene            21349..23094
                     /locus_tag="VYN42_000395"
     CDS             21349..23094
                     /locus_tag="VYN42_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461527.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            23084..24835
                     /locus_tag="VYN42_000396"
     CDS             23084..24835
                     /locus_tag="VYN42_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461528.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            25008..25700
                     /locus_tag="VYN42_000397"
     CDS             25008..25700
                     /locus_tag="VYN42_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1461529.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFLGDI
                     KIMFQTVFEVLK"
     gene            25743..26969
                     /locus_tag="VYN42_000398"
     CDS             25743..26969
                     /locus_tag="VYN42_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1461530.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERCLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            28099..30258
                     /gene="pfbA"
                     /locus_tag="VYN42_000399"
     CDS             28099..30258
                     /gene="pfbA"
                     /locus_tag="VYN42_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1461531.1"
                     /translation="MVKNSKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDLKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            30242..30538
                     /locus_tag="VYN42_000400"
     CDS             30242..30538
                     /locus_tag="VYN42_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461532.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            30780..31088
                     /locus_tag="VYN42_000401"
                     /pseudo
     CDS             30780..31088
                     /locus_tag="VYN42_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            31252..31911
                     /locus_tag="VYN42_000402"
     CDS             31252..31911
                     /locus_tag="VYN42_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1461533.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIYMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            31936..33003
                     /locus_tag="VYN42_000403"
     CDS             31936..33003
                     /locus_tag="VYN42_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1461534.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            33107..34117
                     /locus_tag="VYN42_000404"
     CDS             33107..34117
                     /locus_tag="VYN42_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461535.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            34129..35820
                     /locus_tag="VYN42_000405"
     CDS             34129..35820
                     /locus_tag="VYN42_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1461536.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTECFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            35823..36533
                     /locus_tag="VYN42_000406"
     CDS             35823..36533
                     /locus_tag="VYN42_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1461537.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            36629..>36805
                     /locus_tag="VYN42_000407"
     CDS             36629..>36805
                     /locus_tag="VYN42_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461538.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINS"
BASE COUNT        11243 a         6377 c         8075 g        11110 t
ORIGIN      
        1 cgtactattc caaactcaac caactatata tttaaagaaa gaagaaaggg aagtcaacta
       61 ttttctgtaa atttcatgaa aaatccaaac aactttgatg gtgtattgtt tttttgtttg
      121 gaaataaata ttcgagttaa ttttggaatg tttactagat tttgcactac atgcaagaga
      181 atactatcct tttctaagat agagcaggac taagatacta acttagaaat ccaccttccc
      241 actatccttc tcctataaaa agtggtaaaa tggatgaaag aaagaaggaa ctgaaatgac
      301 aacattattt tcaaaaatta aagaagtaac agaacttgct gcagtctcag gtcatgaagc
      361 gcctgtccgt gcttatcttc gtgaaaagtt gacaccgcat gtggatgaag tggtgacaga
      421 tggcttgggt ggtatttttg gtatcaaaca ttcagaagct gtggatgcac cgcgcgtctt
      481 ggtcgcttct catatggacg aagttggttt tatggtcagc gaaatcaagc cagatggtac
      541 cttccgtgtc gtagaaatcg gtggctggaa ccccatggtg gttagcagcc aacgtttcaa
      601 actcttgact cgtgatggtc atgaaattcc tgtgatttca ggttctgttc ctccgcattt
      661 gactcgtgga aaggggggac caaccatgcc agccattgcc gatatcgttt ttgatggtgg
      721 ttttgcggac aaggctgagg cagaaagttt tggcatccgt cctggtgata ccatcgtacc
      781 agatagttct gcaattttga cagccaatga aaaaaatatc atctcaaaag cttgggataa
      841 ccgctacggt gtcctcatgg taagcgagct agctgaagct ttatcaggtc aaaaactcgg
      901 caatgaactc tatctgggtt ctaacgtcca agaagaagtt ggtctgcgtg gcgctcatac
      961 ctctacaacc aagtttgacc cagaagtctt cctcgcagtt gattgctcac cagcaggtga
     1021 tgtctacggt ggtcaaggca agattggaga tggaaccttg attcgtttct atgatccagg
     1081 tcacttgctt ctcccaggga tgaaggattt ccttttgaca acggctgaag aagctggtat
     1141 caagtaccaa tactactgtg gtaaaggcgg aacagatgca ggtgcagctc atctgaaaaa
     1201 tggtggtgtc ccatcaacaa ctatcggtgt ctgcgctcgt tatatccatt ctcaccaaac
     1261 cctctatgca atggatgact tcctagaagc gcaagctttc ttacaatcct tggtgaagaa
     1321 attggatcgt tcaacggttg atttgattaa acattattaa accataaggg aggtggtagg
     1381 gatggcagaa ccaaacctag aaagccttat aaaagatctt tacaatcatg ctcgacatga
     1441 tttgagtgaa gatttagttg ctgctctcct agagactact aaaaaactgc ctactacaaa
     1501 tgagcaattg caggcagttc gtctctcagg cctggtcaat cgtgaattgc tcctaaatcc
     1561 caaacatcca gcacctgagt tgctcaactt ggctcgcttt atcaaaagag aagaagccaa
     1621 gtacagagga actgcgactt ctgcacttat gtatgaggaa ctttttaaaa tgctttgatt
     1681 ccattgtgga tcaaagcatt ttttataaga cctatctcgt gagcgttcaa atagtagtaa
     1741 caaggaatca tgagaagtca gccgagacca tagtagtgaa gaaacttctg taatggaagt
     1801 ggagtgaagt gaggaatcgt caaacggtag gggataggct gtttgaaggg tgctacgaaa
     1861 aagatagggt aaggtgaaat tatagcggaa tgaaataaga tatgaacaaa ttgattaggg
     1921 aaatcaaatg aatttataga aatcttttag cagtcatggt gtcctattcc agtttcgaaa
     1981 tgctataaag acgaacaaat tgattgggaa attcaaatcg ctttctatca atgttttaga
     2041 agatacagtg ccctagtcca acttcaatat actataaaag aacagatgga agcaattatg
     2101 atttatttct atctttaaaa taaatgctct gataggaaaa atgtgtcccc tcataaaata
     2161 taggatagta cggatggaag gcttttgtag actggaggac gaaggagttt agaaactctc
     2221 gttaaaagtt agttgagccg gagtatggtg gtgtggataa ttatcaaaaa ttatttctaa
     2281 atcgaaatag ttgacagtta gaacgatgag tgttacaatt gttttattca tttcgatatc
     2341 gaaataaatt ggaggtgtta tgaaagatgg tcatttgcta gcccatcata ttcgtttgtt
     2401 gaatgggcgg atttttcaaa agttactgag tcaagatcct gaggctcttt ataggggtga
     2461 acagggcaag attttagcgg ttttatggaa tagtgaaact ggctgcgcaa ctgcgacaga
     2521 tatcgcgctt gcgactggac ttgcgaataa tacgctgacg actatgataa aaaagctaga
     2581 ggaacaaaag cttgtaattg ttagtccgtg tggaaaagac aagcgtaaga agtatttagt
     2641 tttaacggag ttaggcaagt cccagaaaga agtggggcat cgtgtcagtc agaaattgga
     2701 tactatcttt tacaaaggat tttcagagga agaaattcac caatttgaag gttttcaaga
     2761 aagaattttg gcgaatctga aagagaaggg aaatgaggtt tagaatatgt cacaacaagt
     2821 gaaaaatgct cacaacctat acatccatgc cattcaagac ggacgagttg ctgaggctca
     2881 agcccagtct gtaggggata cctatatcca acattcgaca ggtgttcctg acgggaaaga
     2941 aggatttgca gccttctttg cagatttctt tgagcgtcat ccagagcgtc agattaagat
     3001 tgtccgcacc attgaggatg gcaatctggt ctttgttcat gttcatcaat atctgaatgg
     3061 tggagaagct caatgggtga cgacggatac tttccgtgag gatgagaatg gttgtattgt
     3121 tgagcattgg gatgtcattg actactatcg aacacctgaa aatgaccaac tagatcaaat
     3181 ttttggagat tttgaaatca aggatttgga taagaaagca gaaaataaaa agctggttcg
     3241 ccgtttcttg acagaaattt tccaaaatgg ggagctagag cagtggagtg attatgtggc
     3301 agacgatttg attcagcata atcatgagat tggacaagga agtgctgctt ataaaaacta
     3361 tgtggctgaa tatagtgtca cttttgactt tgttttccaa ctcttaggac aaggaaacta
     3421 tgtggttagc tatggtcaga ctcagattga tggcgttgct tatgcccagt acgatatctt
     3481 ccgtttagag aacgggaaaa ttgtggagca ttgggataat aaggaagtca tgcctaaggt
     3541 agaagacttg actaatcgag ggaagtttta aattgaggac aaagaatgat tgaatacaaa
     3601 aatgtagcac tgcgctacac agaaaaggat gtcttgagag atgtcaactt acagattgag
     3661 gatggggaat ttatggtttt agtagggcct tctgggtcag gtaagacgac catgctcaag
     3721 atgattaacc gtcttttgga accaactgat ggaaatattt atatggatgg gaagcgcatc
     3781 aaagactatg atgagcgtga acttcgtctt tctactggtt atgttttaca ggctattgct
     3841 ctttttccaa atctaacagt tgcggaaaat attgctctca ttcctgaaat gaaggggtgg
     3901 agcaaggaag aaattacgaa gaaaacagaa gagcttttgg ctaaggttgg tttaccagta
     3961 gccgagtatg ggcatcgctt acctagtgaa ttatctggtg gagaacagca acgggtcggt
     4021 attgtccgag ctatgattgg tcagcccaag attttcctca tggatgaacc cttttcggcc
     4081 ttggatgcta tttcgagaaa acagttgcag gttctgacaa aagaattgca taaagagttt
     4141 gggatgacaa cgatttttgt aacccatgat acggatgaag ccttgaagtt ggcggaccgt
     4201 attgctgtct tgcaggatgg agaaattcgc caggtagcga atcccgagac aattttaaaa
     4261 gcgcctgcaa cagactttgt agcagacttg tttggaggta gtgttcatga ctaatttaat
     4321 tgcaactttt caggatcgtt ttagtgattg gttgacagct ctatctcaac atttgcagtt
     4381 gtcacttttg accttgttac tagctatttt gcttgcgatt cccttggctg tttttcttcg
     4441 ctatcatgag aagttggcgg attgggtctt acagattgca gggattttcc agaccatccc
     4501 gtctctggcc ttgttgggac tctttattcc cttgatggga attgggactt taccggcatt
     4561 gacagctcta gtgatttatg cgattttccc tattttgcaa aatactatca ctgggctgaa
     4621 gggaattgat ccgaacctgc aagaggctgg gattgccttt gggatgacca gatgggaacg
     4681 tctcaagaaa tttgaaattc cacttgccat gcctgttatc atgtctggga ttcggacggc
     4741 agctgttttg attatcggta cggcaacctt ggcggccttg attggagcag ggggactggg
     4801 ttcctttatc ctgttgggaa ttgaccgtaa taatgccagt ttgattttga ttggggcact
     4861 ttcttctgca gtgcttgcta ttgcctttaa cttcctacta aaagtaatgg aaaaagcaaa
     4921 attacggacg attttctcag gttttgcctt ggtggcttta ttactgggtc tgtcttatag
     4981 tccagccctt ttggctcaaa aagagaagga aaacttgatt attgctggga aaataggccc
     5041 agaaccagaa attttggcta atatgtataa attgctgatt gaagaaaata ccagcatgac
     5101 tgcgactgtt aaaccgaatt ttgggacgac aagtttcctt tatgaagctc tgaaaaaagg
     5161 tgatattgac atttatcctg aatttaccgg tacggtgact gaaagtttgc ttcaaccatc
     5221 acccaaggtg agtcatgagc cagagcaggt ttatcaagtg gcgcgtgatg gcattgccaa
     5281 gcaggatcat ctagcctatc tcaaacctat gtcttatcaa aatacctatg ctgtagctgt
     5341 tccgaaaaag attgctcaag aatatggctt gaagaccatt tcggatttga aaaaagtgga
     5401 agggcagctg aaggcaggct ttacgcttga gtttaacgac cgtgaagatg gaaataaggg
     5461 cttgcaatca atgtatggtc tcaatctcaa tgtggcgact atgcagccag ctcttcgtta
     5521 tcaggcaatt cagtcagggg atattcaaat cacggatgcc tattcgactg atgcggaatt
     5581 ggagcgttat gatttacagg tcttggaaga tgacaagcaa ctcttcccac cttatcaagg
     5641 ggctccactc atgaaagaag ctcttctcaa gaaacaccca gagttggaaa gagttcttaa
     5701 tacattggct ggtaagatta cagaaagcca gatgagccag ctcaactacc aagtcggtgt
     5761 tgaaggcaag tcagcaaagc aagtagccaa ggagtttctc caagaacaag gtttgttgaa
     5821 gaaatgatgg gacagagact ttaaacatac tgaactcaac ttccttaaac gactagataa
     5881 aagaatgctc agacaatttc gtctgggctt ttttgatgtg agaatgactg aatgtcactt
     5941 aaaatggaaa gaaagagaaa attttcatga ttttctaaaa ttttactgta aagacagttg
     6001 actattcata aaataggtgt ataatatttt atgaactact taacaaataa gaagtttcag
     6061 ctcatgtcga ctaaggttag aaatcttgtg tataggcagt tcattatcta atagagcgtt
     6121 gcgtccgaaa gtctatccag acacggctct ttaaaaacaa aaggagaaat gatgcatact
     6181 tatttgcaaa agaaaattga aaatatcaaa acaaccctag gtgaaatgtc aggtggttac
     6241 cgtcgtatgg ttgcggctat ggctgattta ggattttcag gaactatgaa ggctatctgg
     6301 gatgacctct ttgcccatcg tagttttgcc cagtggattt atttgctggt tttaggaagt
     6361 tttcctctct ggctggagtt ggtttacgaa catcgtattg ttgactggat tgggatgatt
     6421 tgtagcttga cagggattat ctgtgtaatc tttgtatcgg aaggtcgagc aagtaattat
     6481 ctttttggct tgattaactc tgttatttac cttattttgg ccctacagaa aggcttttat
     6541 ggtgaggtgc tgacgacact ttacttcaca gtcatgcagc caattggact tctagtttgg
     6601 atttatcagg cacagtttaa gaaggaaaag caggagtttg tcgcgcgtaa actggacggc
     6661 aagggctgga caaagtatct ttccattagt gtgctttggt ggttggcctt tggcttcatt
     6721 tatcagtcta ttggtgccaa tcgtccctat cgtgattcaa tcacagatgc aaccaatggg
     6781 gtagggcaaa tcctcatgac agctgtttac cgtgaacagt ggatattctg ggcggctacc
     6841 aatgtctttt caatctatct ctggtgggga gaaagcctgc aaattcaagg gaaatatcta
     6901 atttatctca ttaacagtct agttggttgg tatcaatgga gcaaggcagc taagcagaat
     6961 actgatttac ttaactagga aaagatgttt gaaagtgctg ttttgagatt tcgattaaaa
     7021 cagatatagt tgataatcaa ggatttatag tatgaaaaag aggatcggcg ggtcctcttt
     7081 tgttgttgaa aagataaaaa actcagtaat ctagaaataa gacaactgag ctttactcta
     7141 tattcaattt ttaggaatga gaaggtctag ataaaattgg acaacttcct ggtctgtgaa
     7201 atcttgacct tttttgagcc accaggtcaa tgtctcgata aagttggaca tgaccaagtg
     7261 ttggaggtaa gaagtaggca gattagggtg ggcttctttt aaattatcag ctagcacgga
     7321 atagacgtgg tgctcaagct ctctctggag ttgacggagg aagtagtcat ttttggaaaa
     7381 tagcagactg gtgatatggt cttggttttt atgaaaatgg agaaagaggt gggcgaggta
     7441 gtcctcggtt gaaatggctt gctctctttc aaaaagatga tggaagaggt agcggcagag
     7501 ctggtccaga agaagctcct tactttcata gtgacagtaa aaggtggatc ttcccacatc
     7561 tgcgagatca atgatatcct gaacagtagt ggcctcgtag cccttagcat tcaaaagttg
     7621 tataaaagct tgatagatgg cttttttggt tttgctgata cggcggtcaa tgttagtcat
     7681 atggacactt aaggcaaatt gttcagaact gaataaagct gacgttttgc ttctatcctt
     7741 tctttgagtt ttagtggata atgataatga acaaggtgtt cataaatcta ttataacaaa
     7801 ggaatgagaa atatgaaggc aaaatatgct gtttgggtgg cttttttctt aaatttgact
     7861 tatgccattg ttgagtttat tgcaggtgga gtatttggtt ctagcgctgt tcttgctgac
     7921 tctgtgcatg acttgggaga tgcgattgca attggaatat cagcttttct agaaacaatc
     7981 tccaatcgtg aagaagacaa tcagtacacc ttgggctata agcggtttag cctgctagga
     8041 gccttggtaa cagctgtgat tctcgtaacg ggctctgttc tagtcatttt ggaaaatgtc
     8101 acgaagattt tgcatccgca accagtcaat gatgagggga ttctctggtt aggaattatt
     8161 gcgattacta tcaatctgtt agcgagtctg gtggttggta agggaaagac aaagaatgag
     8221 tctattctga gtttgcattt tctggaagat acgctagggt gggtagctgt tatcctgatg
     8281 gcgattgttc ttcgatttac ggactggtat atcctagatc ctcttttgtc ccttgtcatt
     8341 tctttcttta ttctttcaaa agcccttcca cgtttttggt ctacactcaa gattttcttg
     8401 gatgctgtgc cagaaggtct tgatatcaag caagtaaaga gtggcctgga gcgattggac
     8461 aatgtggcca gccttaatca gcttaatctc tggactatgg atgctttgga aaaaaatgcc
     8521 attgtacatg tttgtctaaa agaaatggaa catatggaaa cttgtaaaga gtctattcga
     8581 attttcctaa aagattgtgg ttttcaaaat attaccattg aaattgatgc tgacctagaa
     8641 actcaccaaa cccataagcg aaaggtgtgt gacttggaac ggagttatga gcatcaacat
     8701 tagaaaaaag tgaaaaatac ttgggtacta tcttatttgg aatagagtaa tttctttatt
     8761 atttaaatat ttcaaaaatt ggtaagagaa gagcattgta taaactccag atatatgatt
     8821 gttaatgata aaaatttttc gattagatac aaaatgcttg acttggagtc aactcaaagt
     8881 tatataataa gataagtgag ttagaatagc gtgaattcag tgaatgaaat gagaggaggt
     8941 tagcgtgtga atattaaatc tgccagtgat ttgttgggaa tttcagcgga tacgattcgg
     9001 tattatgaac gggttggtct tgtgccaccg attactcgta ctgctactgg gattcgtgat
     9061 tttcaagatc aggatatcga agcgctggaa tttattaagt gttttcgttc ggcgggtgtc
     9121 tctgtagata gtttagttga ctatatgtcg ctctaccaaa agggagatga aacgagagag
     9181 gagaggcttg gtattttaga agaggaaaag caaaaattag aggagcgctt gtctcagcta
     9241 cagacagctt taaatcgttt aaatctcaaa attaaacttt ataaggaagg aaaattttaa
     9301 atgaaatcag cagtatatac aaaggcaggt caggttggac ttgctagcat tgaacgtccg
     9361 caaataatag aagcggatga tgtgattatt cgtgtggttc gtgcgtgcgt ttgtggttca
     9421 gatttatgga ggtaccgtaa tccagaaacg aaagctggac ataaaaatag tggacacgaa
     9481 gcgattggga ttgttgaaga agctggggaa gccattacga cggtgaaacc aggtgatttt
     9541 gtgattgtcc cttttacaca tggatgtggt gagtgtgatg cctgtcttgc tggatttgac
     9601 ggttcttgcg acaatcatat tggcaataat ttggggggtg attttcaggc agaatatatt
     9661 cgcttccact atgcaaactg ggcgctggtt aaaatccctg gtcaaccttc tgattataca
     9721 gaagggatgc tcaagtccct tttgactctt gcagatgtca tgccgacagg ctatcatgca
     9781 gcgcgtgttg caaatgttca aaaaggggat aaggttgttg ttataggtga tggggctgtt
     9841 ggtcaatgtg ctgtcatcgc ggctaagatg cgtggagcat cacaaattat ccttatgagc
     9901 cgtcatgaag accgtcaaaa gatggctatg gagtcaggtg cgacagctgt tgttgcagaa
     9961 cgtggtcaag aaggaattac caaggtgcgt gaaatcctcg gtggaggagc agacgcagca
    10021 cttgaatgtg ttggtacgga ggctgctata gaacaggcgc taggtgttct tcataatgga
    10081 gggcgtatgg gctttgtagg agtcccacac tataataatc gtgctcttgg ttcgacattt
    10141 atgcaaaata tctctgtagc aggtggggca gcttctgcta caacatacga taagcaattt
    10201 ttactaaaag tcgtccttga tggtgatatc aatccaggtc gcgtctttac ttcaagttat
    10261 aaactggaag atatcgacca agcctacaaa gatatggatg aacgtaagac aattaagtct
    10321 atgattgtaa tcgaataaaa aacgaatagg agttttagaa ctctattcgt tttttatgtt
    10381 atcctattct tgatttaggg tactttctct taatgtcagt ctggttccca gcatggtcag
    10441 gctagggatt ttccgaccgt ggaggacttc cttgttaaga atatccatac ctgctcggcc
    10501 catttcttca gtataaactg taatactaga gaggggagga tagacctgtt tggtcagact
    10561 ggtgtcgttg aatgaaatga ggctgacgcg atctggcagg ctgattccag cttcttggag
    10621 ggcacggagg gcaccgatag ctaaactatc gctggctgcg aaaaatgctg gcggaagttg
    10681 gtctcccaag ctctgaatgg cctccttcat taagtcatag ccagactggg cagtaaatct
    10741 tccttgaaag accagttcat catgatagat tcccctcgct tgactgtagt ttctaaaatt
    10801 ttccagccgc ttatcctcaa tgatttcttc ttggtctgtt gtttcttcaa ggcctgttag
    10861 aatcccgata cggtccattc cttggctgag gaaataatcg acaacctgtt tcatagcagt
    10921 gtaaaaatcc gtgataatac aggtatgtcc cagggaaagt gtatcgctgt ctagaaatac
    10981 aagaggcttt tggtattctt caaaggcaga aatctgagct cgactaaact ttccgatgca
    11041 gagaatccca atcacttcct cgcttagggt aaaagggtgg tcattaaaat agcgcaagat
    11101 atcgtagtcc aactcttggg ctcttttttc tattcctagg cgaatctggt agtagtagag
    11161 gtcgtctagc tccccttgtt cgctgaccca ttgaataatg gcaatctttt gcttgggttt
    11221 atgggactcg cctgtcttga ggtgcttggt gtagcccagc tcttcagcaa cggttaaaat
    11281 acggtgtctg gtttcttctg taacagatag gctctggtcg cggttgagaa cacgggatac
    11341 ggtcgcgata gagacagagg ctagctgtgc aatgtctttt aaggtagcca taaatcctcc
    11401 ttgattaggt tagtatatca tatttttctg ctttttactg atattttagt aaaattttag
    11461 taaaaaggat tgaccttggg aaatcccttg gatacaatag aagaaaacga ttacacgtta
    11521 aggtggctta acggacagtc aaaggagaaa tcatatgaca caacatctta ctgctgaaac
    11581 tcttcgcaaa gactttcttg ctgtttttgg tcaagaagca gaccaaacct tcttttcacc
    11641 aggtcgtatc aatttgattg gtgaacacac agactacaac ggtgggcacg tttttccagc
    11701 tgctatttcc ttgggaactt atggtgcagc tcgcaagcgt gaagaccaag ttttacgttt
    11761 ctactcagct aactttgagg acaagggcat tatcgaagtg cctctcgctg acctcaagtt
    11821 tgaaaaagag cacaactgga ccaattatcc aaaaggtgtc cttcatttct tgcaagaagc
    11881 tgggcacgtg attgacaaag gttttgattt ttatgtttat gggaatatac caaatggtgc
    11941 tggtttgtct tcttcagcat ccttggagct cttgacagga gtcgtggcag agcatctctt
    12001 tgatttaaaa ttagagcgtc tcgatttggt taaaatcgga aaacaaacag aaaacaactt
    12061 tatcggagtc aactctggta tcatggacca gtttgctatt ggtatggggg ctgatcaacg
    12121 tgctatttac cttgatacca acaccttaga gtatgatttg gtgccacttg atttgaagga
    12181 caatgtcgtt gttatcatga acaccaacaa acgccgtgaa ttggcggact ctaaatacaa
    12241 tgaacgtcgt gctgagtgtg aaaaagcagt ggaagaattg caagttgcct tgtatattca
    12301 gaccctgggt gaattggacg agtgggccgt tgaccaatat agctatttga ttaaagatga
    12361 aaatcgtttg aaacgtgctc gccatgctgt gcttgaaaac caacgtaccc ttaaagctca
    12421 agcagccctt caagcaggtg atttggaaac atttggtcgt ttgatgaatg cgtcacacgt
    12481 ttctctggag catgattatg aagtaactgg tttggaatta gatacccttg ttcacacagc
    12541 ttgggcacaa gaaggagttc tcggtgctcg tatgacaggg gctggttttg gtggctgtgc
    12601 cattgccttg gttcaaaaag atactgttga ggcctttaag gaagctgtag gcaaacacta
    12661 cgaggaagta gttggatacg ctccaagctt ctatatcgct gaagttgcag gtggcactcg
    12721 cgtccttgac tagtcaaaag gaggctctat agtgacctta gtagataaat ttgtaacaca
    12781 tgtcatttct gaaagttcat ttgaggaaat ggatcgaatc tacctgacca atcgtgtttt
    12841 ggcacgagtg ggagaaggtg ttttggaagt tgagaccaat ctggataaat tgattgacct
    12901 caaggaccag ctagttgagg aagccgttcg attagagacg attgaggata gtcagactgc
    12961 gcgtgaaatc cttggtactg aattgatgga cttggtgact ccttgtccga gtcaggtcaa
    13021 tcgtgacttc tgggaagcct atgcctactc tcctgagcaa gcgatagagg atttttatca
    13081 actcagtcag aaaaatgact acatcaaact caaggccatt gctaaaaata tcgcttatcg
    13141 tgttccatct gattatggag aacttgaaat taccatcaat ctctctaagc ctgaaaagga
    13201 tccgaaagag attgcggcag ccaagttggt gcaagctagt aattatcctc agtgtcaact
    13261 ttgtttagag aatgagggtt accatggtcg ggtcaaccac ccagctcgca ccaaccaccg
    13321 gattatccgt tttgaaatgg ttggtcagga atggggtttc cagtattcgc cctatgctta
    13381 ctttaatgag cattgtatct ttttagatgg ccagcatcgt cccatggcca ttagtcgtca
    13441 gagttttgaa cgtctgttgg ctatcgtaga gcagtttcca ggatattttg ctggatctaa
    13501 tgccgacctg ccgattgtgg ggggctctat tctaactcat gatcattatc agggaggccg
    13561 tcacgtattt cctatggaat tggctccctt gcaaaagacc ttccgatttg ctggttttga
    13621 gcaggtcaag gctggaatta tcaagtggcc catgtctgtc ctacgcttga cttcggattc
    13681 caaagaggat ttgattaact tagctgataa gattttccag gaatggcgtc agtattcaga
    13741 ttctagtgtg cagattttgg cagagacaga cgggacaccg catcacacca tcacaccaat
    13801 agcgcgtaag cgtgatggac agtttgagtt ggacttggtc ttgcgagaca atcagacttc
    13861 agcagagcat cctgatggca tctatcatcc ccacaaggat gtccaacata tcaagaagga
    13921 aaatatcggc ttgattgagg tcatgggctt ggcaatcttg ccaccacgtc tgaaagaaga
    13981 agtggagcaa gtcgctagct atcttgtagg agaaactgtt acagttgccg attatcatca
    14041 ggagtgggca gaccaactca aatcccaaca tccagaccta acggataaag aaaaagccct
    14101 tgcaatcgtc aaggactctg tgggtgctat ctttgtgcgt gtacttgagg atgcaggagt
    14161 ctacaagcag acagaacaag ggcagacagc ctttatgcgc tttgtggaac atgtcggaat
    14221 ttcactagac taggagcttt ctccttgcac agtcctataa aaagtagtat catagtgtcg
    14281 tttgaaatat caggaggaaa cgatgaaaga ctttcatttt gacgctatat ctgcctttga
    14341 aaattacgaa attgaaaaaa tgagagatgg tcacgttgtg gtgacgacca aagtagtgaa
    14401 ctcgtcgctc aactactatg gcaatgccca cggtggctat ctattcacgc tatgtgacca
    14461 aatcagtggt ttggtggtta tctcgctggg acttgatggg gtgacactcc aatcctctat
    14521 caactacctt aaggcaggaa aactcgacga tgtattgacc attaaaggag aatgtgtcca
    14581 tcaaggccgt acaacctgtg tgatggatgt ggatatcacc aatcaagagg gcagaaatgt
    14641 ctgtaaagca acctttacca tgtttgtcac aggccaaagg tctgaggaaa gacaggtaag
    14701 gatataaaga aaggtgagtg ggataaattt atctcactca tttttaattt atgagatatg
    14761 ttagaaggaa atataaaaga gagtgatgaa atacaaatgt aataggtaca tatatgtggt
    14821 atactagtta tagtagattt taattgctta tatcgagtga gttctcatat tagtgaggaa
    14881 tttttaaatg gaattacact ttaatttaga attagtagaa acctataaaa gtaatagcca
    14941 aaaggcacgt atcttaacgg aggattgggt ttatcgtcag tcttattgcc ctaattgtgg
    15001 gaacaatccc ttaaatcatt ttgaaaataa tcggcctgta gcagattttt actgtaatca
    15061 ttgtagtgag gagtttgaac taaagagcaa aaaaggaaat ttttcatcaa caatcaatga
    15121 tggtgcttat gcaacgatga tgaagcgtgt gcaggcagat aataatccta atttcttttt
    15181 ttaaacttac acaaaaaatt ttgaggtaaa taactttctt gtccttccga agcaatttgt
    15241 tacaccgaaa tcgattattc aaagaaaacc acttgcacca actgctagac gagcaggttg
    15301 gattggttgt aacattgatt tatcacaagt accttctaaa ggaaggatat ttcttgtgca
    15361 agatggacaa gttagagatc cagaaaaagt tacaaaagaa tttaagcaag gtttattttt
    15421 aaggaagagc tctctgtcat caagaggttg gacaatagaa attctaaatt gtatagataa
    15481 gatagagggt tcagaattta cccttgaaga tatgtatcgt tttgaaagtg acctaaaaaa
    15541 tatctttgtt aagaacaatc atatcaaaga aaagattagg caacagcttc aaatattaag
    15601 agacaaagaa ataatagaat ttaaaggtag aggaaagtat cggaaattat gaaaacgaaa
    15661 caacttgttg catcagaaga ggtgtatgat ttcttaaaag tcatctggcc tgattatgaa
    15721 actgaaagcc gttacgataa cctaagttta atcgtctgta ccttatcaga tcccgattgt
    15781 gtgagatggt tatctgaaaa tatgaaattt ggtgacgaaa aacaactagc tttgatgaag
    15841 gaaaaatatg ggtgggaagt aggagataaa ttgccagagt ggctacatag ctcctatcat
    15901 agattattgt taataggtga attattggaa agcaatctaa aactgaaaaa gtatacagta
    15961 gaaattacag aaactttatc acgtttagta agtatagagg ctgaaaatcc agatgaagcc
    16021 gaacgacttg taagagaaaa gtataagagt tgtgaaattg ttcttgatgc agatgatttt
    16081 caggactatg acgctagcat atatgaatag gtagatgttt ttattttgtc acacaaaaaa
    16141 gaggctcgca cctctttttc ttatttcttt ttatgattta atacggcatt gaggacaata
    16201 gcgagtaggc tggctacgac gattcctttt gagaagaaca tttggaaggc tgtcggcatg
    16261 ctgacaaaga gattactgtt gttgagaccg acacctgcag cgattgaaac agctgcgata
    16321 aggaagttgt gttcattgtt agcaaagtca actcgggcga ggatttgcat cccttgaata
    16381 gatacaaaac caaacatcac cagcatggca ccgccgagga cggagcttgg aatgatttgg
    16441 gcaagggcac caaacttagg aagcagtcca aggagaacca ggaaaccagc tgcgtagtag
    16501 attggcaggc gttttttgat gcctgacaat ttaaccaaac caacgttttg tgaaaatccg
    16561 gtgtaaggga aggtgttaaa gattcctccg agaagtaccg ccaaaccttc tgcgcggtaa
    16621 ccgttgcgaa ggcgcgtgct gtcgattgga tcttttgtga tatcagacaa ggctagataa
    16681 acaccagttg actcaaccat agacaccgtt gcgataatac acatcatgac aatagatgag
    16741 atttcaaagg ttggcatccc aaagtagagt ggagttggga catggacaag tggagctacc
    16801 gcaacaggag agaagtccac caagcccata gtagcagcaa tggcagttcc aacaaccaga
    16861 ccaatcaaaa tagagataga cttgataaat cctttggtaa agatgttgat caagaggata
    16921 atcagaacag taatagctgc aagcaagaga ctttgaccag ttggctctgg aacgttattt
    16981 cccatatttc caatagcgac agggatcaag gttaaaccaa tcgtggtaat aacagatcct
    17041 gttacgatag atgggaaaag attggctact tttgagaaga tgcctgaaac aagaaccacg
    17101 taaattccag atgcgataag ggcaccaaac atagcgctac taccatggct ttgcccaatc
    17161 ataatcaagg gagcgaccga ctggaatgca actccaagaa cgactgggag tccaatccca
    17221 aagtatttgt tgagttggag ttggaggaag gttgccaccc cacacatgaa gatatctgta
    17281 gaaatcaggt aggtcaactg ctcagctgaa tagccaaggg ctgtcgcaat catgatggga
    17341 accaggatag atcctgagta catggctagt aagtgctgca agccaagaac ggctgcttgc
    17401 gagtgttttt cttgagtttg cattagagat ctgcctcctt aaatacgacc tgaccatttt
    17461 caaaacgatc caaacgagca agtgatagga cagggtagcc tgctttttca agcaaatcac
    17521 gaccatcttg gaaggatttc tcaatcacga taccgatagc ttggactgtg gcaccggcct
    17581 gttcgatgat ttgaatcaag cctttagcag cttggccatt agcaaggaaa tcgtcgataa
    17641 tcaaaacctt atcttctggt gagaggaatt ttccagcgat agaaacggtg ctggtcacct
    17701 gtttggtaaa ggagtagact tgagcagtta agatgccttc gttcatggtg atgttcttag
    17761 cttttttggc gaaaatcatg ggaacgttta aggcttcagc tgtaaaaacg gctggggcaa
    17821 tacccgacgc ttcaatggtt acgaccttgg taatgccagt agcagcaaat ttttccgcaa
    17881 aaaccttacc aatctctcgc atcaagctaa agtcaacttg gtgggttaaa aaggaatcta
    17941 ccttgaggat gttatcaccc aagatatgcc catccttgag gatgcgctct tctaataatt
    18001 tcataagacc tcctaaagtc taaaagttaa tttacttgtt gtttaaatat ttctatagtg
    18061 atcccttttg ctaatactat atatttgata aaactattac gagcgaagcg agtcttatca
    18121 aatatttccc gttgtagtgg tatcatagac aataatcttg ttattgtcta tgacgggatt
    18181 tttgagagta aaatagttcg gggaactatt ttagcctaag cctagaaatg aaagagctag
    18241 gggctcaaaa attagggatg aaattccctg gattcctgaa attattcaca ggataatttc
    18301 acctcccgtc cgcactaatt aagggaaata ttaaaaatat tcaaaaaaag acctacttaa
    18361 tctctaagta agtcccccaa ataggcatgg caaaaacggc catatctcac tgctgactta
    18421 cttattgtta ggtgttccgg caccttgtag aaacgtcgtg ccaattcacg acataaacaa
    18481 gtaaaacgat attcaatttt aaataggctt gagccaatgt ttttatttta cactaaataa
    18541 ctttagaaat caactatttt gttagtgttt tggtttaaaa aacgaacaaa cagaagagag
    18601 ggcgaacaaa aaactccgtt gtaagctaac atttatacta aatgaaaatc aaagagcaaa
    18661 ctaggaagct atccacaacc tcaaatcact gttttgaggt tgtggataga attgacagag
    18721 tcagtatcat atacctacgg taaggcaacg ttgatgtggc ttgaagagat tttcgaagag
    18781 tattagaaga tttttccatc ataaaaggca tactatcaag tttttaaaca cctgacaata
    18841 tgcctttttc taactttaaa gacttttccc aatttttatt attctactcg ctaaatctta
    18901 aaaaatagcc atttggatcc aaaactgcaa attcatgagg atagatatag tgatcactga
    18961 cacgaaactt tctcttggtc aagggacgat aaataggata gtttgccttc atcactcttt
    19021 aatagagttt tgaaacatcc tttatgccaa aggagagatt gactccacga ccaaatggat
    19081 aggtcagttc agctagttga tcctttgttc cctcctctaa cattagttga cactcttcaa
    19141 gagaaagaga aagttttctt ctggacgttg gtattcaatc ctaaaaccca gtaaaccaca
    19201 gtagaaggac cgggactgtt cgatattcga tacaagcaac tcgggaatga ccgcattgta
    19261 gtccatatag aaaatcctta caagtcaatt tccaagacaa tcggtgtatg gtcttggcga
    19321 gcacctgagt caatcatatc agatttagtg accttgtcag cgatacggtt acttgtgagc
    19381 cagtagtcga ttctccagcc tgtattgttg attttagaag ttttgctgcg ttgtgcccac
    19441 caagtgtagc gttcaggaac atcgccatga acatggcgga aggtgtctgt aaatccagtt
    19501 gccaaaaggt tggtaaatcc agcacgttcc tcgtcagtaa atccaggtga acggcggttg
    19561 ctagcaggat ttgcaaggtc gatttcattg tgggctacgt tgtagtcacc ggtcgcaagg
    19621 actggttttt ctttgtctag ttcagccaaa tactcagcat atttggcatc ccagacttgg
    19681 cgttcttcca agcgtttgag accgtcacca gcgtttggag tgtaaacttg ggttacgaaa
    19741 aatgcatcaa attctagagt gatgatacga ccttccaagt ccatggtaga aggggcaccg
    19801 atttctggga agctgatagt aggtgtaagt tctttcttat aaaggaacat ggttccagca
    19861 tagcctttac gggcaggctc ttgggaagaa cgccacgtgt tttcgtagcc tgggaagagt
    19921 tcttctaaaa tttccacgtg tttctttgta ggtcctttgg cagaaagctt ggtttcttgg
    19981 atagcaatga tatcagcatt ttcagcgacc aaggtttgta ggacttcttg ggacaatttg
    20041 gcacgagctg agtcactagt tagggcagcg tttagggaat caatattcca tgagataagt
    20101 ttcataaagt tacctttttc attcagatta tagattttat tataccaaaa aaagatctat
    20161 ttccccaacg tatagtttga aaaattactc tctttcgttt ataattaaga atgattttat
    20221 gaaagggagt gaaaatacat gaaattctac tcttatgact atgtactcag ccaaatcggt
    20281 cagcaaaatg gtatcatggt tggctttggg attgttctat tagctgtgac agtttttttg
    20341 cttttaaggc ataccatgat aaaaagggaa ccgaatttcg tgagttggtc atgatttcag
    20401 ctctggcctt atttagctct gcttttggtc agcatcacga cttatcaaaa caatcaagtt
    20461 tctaacaata aatttcaaac ttcacttcat ttcatcgagg ttgtttccaa agatttggga
    20521 gtagacaagt cagaagtcta tgttaatact tccacaaaca cagatggcgc acttatcaag
    20581 gtgggagaac gctattatcg tgccctaaac ggaagtgagc cagacaagta cctgttagag
    20641 aaagtcgaat tgtataagac agacgcaatt gaactggtgg atgtgaacaa atgacactta
    20701 attatatcga aattttaatc aaactggtct tgactctcaa atagctcaac aacaatgttc
    20761 actttgtgaa acgtttgatt gatggtaagc caactctcct tatcaaaaat gggaatattg
    20821 acccataagc ctgtcgttca gttggtttgt ctgcatcgga tgtagccctc aaacttcgta
    20881 gccaagggat tttccagatg aagcaagtca aacgagctgt gcaagagcaa aatgggcaac
    20941 tcatcgttgt gcaaatggga gatgaaaatc ctaagtatcc agttgtgact gacggtgtga
    21001 ttcaagtaga tgtcttggaa tcgattggtc gtagcgaaga gtggttgctt gataacctca
    21061 gtaaacaagg gcatgacaat gtagccaata tctttattgc tgaatatgac aagggtgctg
    21121 ttacagtcgt aacttatgaa aaagaaaaac ctggggtctt gtactcttcg aaaatctctt
    21181 caaaccgcgt caacgtcgcc ttgccgtatg taggttactg acttcgtcag ttctatctac
    21241 aacctcaaag cagtgctttg agcagcctgc ggctagtttc ctagtttgct ctttgatttt
    21301 cattgagtat tggcctcagg tttccatttg caatcagaaa gggattttat gtccattatt
    21361 caaaaacttt ggtggttttt caagttagaa aaacgccgtt atctagtcgg aattgtggcc
    21421 ctggtcttgg tttccgtcct caatctcatt cctcctatgg ttatggggcg ggttattgat
    21481 gccatcacat cggggcaatt aacccagcag gacctccttc ttagcctatt ttacttgcta
    21541 cttgcagcct ttggtatgta ctatttgcgc tatgtgtggc gtatgtatat ccttgggacc
    21601 tcttattgct tgggacagat catgcggtct cgcttgttta agcatttcac aaaaatgtcg
    21661 tcagcctttt atcaaaccta tcggacgggt gatctgatgg cacacgcaac caatgatatc
    21721 aatgccttga ctcgtttagc aggtggcggt gtcatgtctg cggtggatgc ctctatcacg
    21781 gctctggtga ctttgttgac catgctcttt agcatctcat ggcagatgac tcttgttgcc
    21841 attctccccc tacctttcat ggcctatgcg actagtcgcc tagggagaaa gactcataag
    21901 gcctttggcg aatcccaagc tgctttttct gaactcaata acaaggtaca ggagtccgta
    21961 tcaggtatca aagtgaccaa gtctttcggt tatcaggcag acgagttgaa gtcttttcag
    22021 gcagtcaatg aattaacctt ccaaaagaac ctgcaaacca tgaaatatga tagtctcttt
    22081 gaccctatgg ttctcttgtt tgttggttcg tcctatgttt taacgctttt ggttggctcc
    22141 ttggtggttc aggaagggca gattacagtt gggaatctag tcacctttat cagctatttg
    22201 gatatgctgg tctggcctct tatggccatc ggcttcctct ttaatactac tcagagaggg
    22261 aaggtttctt accagcggat tgaaaatctt ttgtctcagg aatctcctgt acaagacccg
    22321 gagtttcctc tggatggtat tgaaaatggg cgtttggagt atgccattga cagctttgct
    22381 tttgaaaatg aggaaacact gacggatatt cactttagtt tggcaaaagg gcaaacactg
    22441 ggcttggttg ggcagacagg ctctgggaaa acgtccttaa tcaagctcct cttgcgtgaa
    22501 tacgatgtgg ataagggcgc catttatcta aacggtcacg atattcggga ctatcgtctg
    22561 acagaccttc gcagtctcat gggctatgtt cctcaggacc agtttctttt tgcgacttca
    22621 atcctagaca atatccgctt tggcaatcct aacttgcccc tttcagcggt cgaggaagct
    22681 actaagctag cccgagttta ccaagatatt gtagacatgc ctcaaggatt tgatacgctg
    22741 attggtgaaa aaggagtcag tctttctggt ggtcaaaagc aacggttggc tatgagtcgg
    22801 gctatgattt tagaccctga tatcttgatt ttggatgatt ccttatccgc cgtagatgcc
    22861 aagacagagt atgcgattat cgacaacctc aaggagacgc gaaaggacaa gacaaccatt
    22921 atcactgccc atcgcctgag tgcagttgtc catgcagatt tgattttagt cctgcaaaat
    22981 ggtcaaatta tcgaacgagg caggcacgaa gacttgctag ctttggatgg ctggtatgcc
    23041 caaacctacc agtctcagca gctggaaatg aagggagaag aagatgcaga ataaacaaga
    23101 acaatggact gtattgaagc gcttgatgtc ctatctcaag ccttatggac tccttacctt
    23161 tttggcactc agttttctcc tagcgacgac ggtcattaaa agtgtcattc cccttgtggc
    23221 ttcccacttt atcgaccagt atctcagcaa tcttaaccaa ctagccgtga ccgttttgct
    23281 ggtctactat ggtctctaca tcctacaaac tgtagttcag tatgtcggca atcttctctt
    23341 tgcgcgcgtg tcttacagta ttgttaggga tattcgtcgg gatgcctttg ccaatatgga
    23401 gaaactgggc atgtcttact ttgacaagac gccagcgggt tctatcgttt ctcgtttgac
    23461 caacgatacc gagacgatta gtgatatgtt ttctgggatt ttatccagct ttatctcagc
    23521 agtttttatc tttctgacaa ccctttatac catgttggtg ctggattttc gtttgacagc
    23581 attagtcttg ctcttcctcc ctttgatttt ccttttggtc aatctctatc gaaaaaagtc
    23641 agtgaaaatc atcgagaaaa ccagaagtct cttgtcagat atcaatagta agctggcaga
    23701 gaatatcgag ggaatcagga ttattcaggc ttttaatcaa gagaagcgcc tgcaggcaga
    23761 atttgatgaa atcaaccaag agcacttggc ctatgccaac cgttctgtag ccttggatgc
    23821 cctctttttg agacctgcca tgagtttgtt gaaacttcta ggttatgctg tcttgatgac
    23881 ctattttggc tatcgtggtc tttctatcgg gataacggcc gggaccatgt atgcttttat
    23941 ccagtacatc aaccgcctct ttgacccttt gattgaggtg acgcaaaact tttcaacact
    24001 gcaaacgtct atggtttctg caggccgtgt ctttgcctta atcgatgaga ggacctatga
    24061 gccccttcaa gaaaatgggc aagccaaagt caaagaaggc aatatccgtt ttgaacatgt
    24121 gtgtttctcg tatgacggta aacatccgat tctggatgac atttctttct ctgttaataa
    24181 gggtgaaacc attgcctttg taggtcatac aggttcaggg aaatcgtcta ttatcaatgt
    24241 cctcatgcgc ttttatgaat tccagtcagg gagagttctc ttggatgatg tggatatcag
    24301 ggatttcagt caagaagagc tgagaaaaaa catcggtttg gttttacagg aacccttcct
    24361 ctatcatgga actattaagt ccaatatcgc catgtaccaa gaaatcagtg atgagcaggt
    24421 tcaggctgcg gcagcctttg tggatgcaga ttcctttatt caagaacttc ctcaggggta
    24481 cgactcccct gtttccgagc gtggttcgag cttctctact gggcaacgcc agcttcttgc
    24541 ctttgctaga acagtcgcca gccagcctaa aatcctgatt ttggatgaag cgacagccaa
    24601 tattgactct gaaacagaaa gcttggttca agcttctctg gcgaagatga gacagggccg
    24661 aacaactatt gctatcgctc accgcctttc tactattcaa gacgccaact gcatctatgt
    24721 cttggataag ggacgcatta tcgagagtgg aacccatgag gaactcttga ctctgggagg
    24781 aacctatcac aagatgtata gtttgcaggc aggggccatg gcctatactc tttgaaaatc
    24841 tctttaaacc atgtcagctt tatctgcaat ctcaaagctg tactttgatt ttcattgagt
    24901 actagaagga aatccttcaa attacagatt tctttcaccg ccttttccat tttgtggtat
    24961 aatgaaaaat gttgacaaat agtataataa aaacaaagga gaacagcatg ctgaaatggg
    25021 aagacttgcc tgtggaaatg aaatcaagcg aggttgagtc ttactaccag cttgtctcta
    25081 aaaggaaggg ttcgctgatt ttcaagcgtt gcttggactg ggttttggcc ttggtcttac
    25141 tggttctgac ctctcccatc tttctcatct tgagcatttg gatcaagttg gatagcaagg
    25201 ggccagtgat ttacaagcaa gagcgtgtga cccagtacaa ccgtcggttc aagatttgga
    25261 agttccgtac catggtgacg gatgcggata aaaaaggaag tctggtgact tctgctaacg
    25321 atagccgtat taccaaggtt ggaaatttca tccgacgtgt ccgtttggac gaactgcctc
    25381 agttggtcaa tgtccttaaa ggtgagatgt cctttgtcgg tacacgacct gaagtgccac
    25441 gttatacaga gcagtatagc cctgaaatga tggcaacctt gctcttgcaa gcaggaatta
    25501 cctctccagc cagcatcaac tacaaggatg aggacaccat catcagtcaa atgacggaga
    25561 aaggtctgtc agttgatcag gcctatgtgg agcatgttct tcctgaaaag atgcgctata
    25621 acctcgccta tctccgagag tttagttttc ttggggacat caaaatcatg tttcaaaccg
    25681 tgtttgaggt actaaaataa agtagtcata agaaaatgag tacagataaa aggagcaaat
    25741 caatgccaaa ttacaatatt ccattttcac cgcctgatat cacagaagca gaaattgctg
    25801 aagtagcgga taccctgcgt tctggttgga tcacaacagg tcctaaaaca aaagaactgg
    25861 agcgctgctt gtctctttac acacagacac ctaagactgt ttgtctcaac tctgcgacag
    25921 ctgctctgga gttgatttta cgcgttttgg aagtgggacc tggtgatgaa gtcatcgttc
    25981 cagccatgac ctatacggct tcatgtagtg tcattacgca cgtgggagca acccctgtca
    26041 tggtggatat ccaagcagat acgtttgaga tggactatga cctgcttgag caagctatca
    26101 ctgagaaaac taaggtgatt atcccagtag agctcgcagg gattgtttgc gattatgacc
    26161 gtttgttcca agtcgtggag aaaaaacgtg acttctttac cgcttcaagc aagtggcaaa
    26221 aggcctttaa ccgtattgtc attgtctctg atagtgccca cgctttggga tctacttata
    26281 aaggacaacc ttctggttct atcgctgact ttacttcctt ctcattccat gccgttaaga
    26341 actttacaac ggcagaaggt ggaagtgcga cttggaaagc caatccagtg attgatgacg
    26401 aagagatgta caaggaattc caaatccttt cccttcacgg gcaaactaag gatgctcttg
    26461 ccaagatgca attggggtca tgggaatacg atatcgttac accagcctat aagtgcaaca
    26521 tgaccgatat catggcttca cttggtttgg tacaattgga ccgctatcca agtttgttgc
    26581 aacgccgtaa ggacattgtg gaccgctatg atagtggttt tgcaggttct cgcatccatc
    26641 ctttggcaca caagactgaa actgtcgaat cttcacgcca cctctacatc acccgtgtag
    26701 aaggagcaag cctagaagaa cgcaacctca tcatccaaga attggctaaa gcaggaattg
    26761 caagtaatgt tcactacaaa ccgcttcctc tcttgacagc ctataagaat cttggatttg
    26821 atatgacgaa ctatcctaag gcctatgcct tctttgagaa tgaaattacc ctccctcttc
    26881 atactaaatt aagcgatgaa gaagtagact atatcattga gactttcaaa acagtttctg
    26941 aaaaagtgct aactttatca aaaaaatgac aaactacagt caagcgaaag tgatcctgtc
    27001 cctaaaaagt ctaattgagt gtaaaaactg ttgttttcaa ttgataatag tttacacctg
    27061 tagttgaggc ctctttctcc tcagagagag aatttttata ggattttcct ttcttgtggg
    27121 agtcccgtgg tttgaaataa gatgtgagca atttggtata gcatttagaa tccttactag
    27181 acatcattta gaaaatctag tgtcttgttc tagttttcaa ttcaccctat tttttgaaag
    27241 acgtgagttt ccatgagtga gattgtggaa actagcgtct tttttttgtt ttcagaatat
    27301 tgttcaaagt tttgtgcctg tctttcatgt tctagtcatt cttttgcatg atagaattta
    27361 tagcatgttg atattataac aacgcaaata tcccatatgt ttagtgatgc ttgctataca
    27421 tcattagatc tcctgcgaga caatctataa aacacttgtc tacgattacc tatatgccct
    27481 attccagtat tttagaagca ctgcatctat ttttatcgag gttaaatcta gcttttatag
    27541 aaggtctatt taagaaatat attgtagtgt tttagtttca atccgccata tgagcgatat
    27601 tcatgtaaat atccctggcg aatgcttgta tgacaagata tttgttcttt catttataat
    27661 ttacaacata tcaacaaatt taaatatagt aaatgggata ttttatattc aagctaagaa
    27721 agatagcatc acttttgaat ggaaggctaa agagcaaact aggaagttgg ccatagatag
    27781 ctcaaaaccc tgctttgagg ttgtagatat aataaaatga aataagaata ggacaaatcg
    27841 atcgggacag tcaaatcgat ttctaagaat gttttagaag tagaggtgta ctattatagt
    27901 ttcagtctac tatagaactg accaagtcag taacctagac ttaggtcaag gcggcactga
    27961 cctagtttga agagatttcc gaagagtata aattttaata ttttcttgtg ttattccttg
    28021 acaattcaat ttggaaaata tatgataaag ataatgacag cggtgtcatt ctatctattt
    28081 taagaaaagt aataatcaat tgttaaaaat agtaaaaaat tggaggttct gatgaaatat
    28141 tttgttccta atgaggtatt cagtattcgt aaattaaagg tggggacttg ctcggtacta
    28201 ttggcaattt caattttggg aagccaaggt attttatcgg atgaagttgt tactagttct
    28261 tcaccgatgg ctacaaaaga gtcttctaat gctattacta atgatttaga taattcacca
    28321 actgttaatc agaatcgttc tgctgaaatg attgcctcta attcaaccac taatggttta
    28381 gataattcgt taagtgttaa tagtatcagc tctaatggta ctattcgttc caattcacaa
    28441 ttagacaaca gaacagttga atctacagta acatctacta atgaaaataa gagttataag
    28501 gaagatgtta taagtgacag aattatcaaa aaagaatttg aagatactgc tttaagtgta
    28561 aaagattatg gtgcggtagg tgatgggatt catgatgatc gacaagcaat tcaagatgca
    28621 atagatgctg cagctcaagg gctaggtgga ggaaatgtat attttcctga aggaacttat
    28681 ttagtaaaag aaattgtttt tttaaaaagt catacacact tagaattgaa tgagaaagct
    28741 acaattctaa atggtataaa tattaagaat cacccttcca ttgtttttat gacaggttta
    28801 tttacggatg atggtgcgca agtagaatgg ggcccaacag aagatattag ttattctggt
    28861 ggtacgattg atatgaacgg tgctttgaat gaagaaggaa ctaaagcaaa aaatctacca
    28921 cttataaatt cttcaggtgc atttgctatt gggaattcaa ataacgtaac tataaaaaat
    28981 gtaacattca aggatagtta tcaagggcat gctattcaaa ttgcaggttc gaaaaatgta
    29041 ttagttgata attctcgttt tcttgggcaa gccttaccca aaacgatgaa ggatgggcaa
    29101 atcataagta aggagagcat tcagattgaa ccattaacta gaaaaggttt tccttatgcc
    29161 ttgaatgatg atgggaaaaa atctgaaaat gtgactattc aaaattccta ttttggcaaa
    29221 agtgataaat ctggggaatt agtaacagca attggcacac actatcaaac attgtcgaca
    29281 cagaacccct ctaatattaa aattttaaat aatcattttg ataacatgat gtatgcaggt
    29341 gtacgtttta caggattcac tgatgtatta atcaaaggaa atcgctttga taagaaagtt
    29401 aaaggagaga gtgtacatta tcgagaaagc ggagcagctt tagtaaatgc ttatagctat
    29461 aaaaacacta aagacctatt agatttaaat aaacaggtgg ttatcgccga aaatatattt
    29521 aatattgccg atcctaaaac aaaagcgata cgagttgcaa aagatagtgc agaatattta
    29581 ggaaaagtat cagatattac tgtaacaaaa aatgtaatta ataataattc taaggaaaca
    29641 gaacaaccaa atattgaatt attacgagtt agtgataatt tagtagtgtc agagaatagt
    29701 atattcggtg gtaaagaagg aattgttatt gaggatttaa agggtaaaat aaccgtttta
    29761 aataaccaat tttataattt atccggtaag tatatatcat tcatcaaatc taatgcaaac
    29821 gggaaagaac ctgttatacg tgatagcgat ggtaatttca atattgtaac ggagaatggg
    29881 ctttacaaaa ttgtaacaaa taatttaagt gataaaaacg aaaaagaaaa aaacaaagag
    29941 gaaaaacaat ctaattcaaa taatgtaatt gatagtaacc agaagaacgg agagtttaac
    30001 tcaagtaaag ataatagaca aatgaatgac aagatcgaca ataaacaaga taataagaca
    30061 gaagaagtaa actataaaat agttggagat ggcagagaaa ctgaaaatca tattaataaa
    30121 tctaaagaaa tagtagatgt aaaacaaaaa ttaccaaaga ctggttcgaa caagattatg
    30181 gaactattct taacagtgac aggaattggt ttacttttga cactaaaagg gttgaagtat
    30241 tatggtaaag ataaataaaa tttgttcgat acaaggaagt tccgtagaaa atgaggatat
    30301 tgtaggttca caaaatcagt atttttggat tattggtgga gctacagatt tatataattc
    30361 taaagaggag ataggttatt cagtctcaga agttgtacat attttatcag aaagtttgtc
    30421 ggttaattgt aaagaatcaa aaactcttaa acaaatattt gaaactgctt tactcgaggt
    30481 taaagatgaa atcggtttaa actcatatga attaacagag tatagtaaaa tgaaataata
    30541 ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt
    30601 gtactattct agtttcaata tactatatta tcgcttacca atatttgcta aactttcaga
    30661 aaaaaagttg gagtatatga tgctaggtga ctgcgtcatg ttagtaaacg aaatggaaat
    30721 aactgatcat agagtagata acttatttga aaaagggaaa aatgagataa aagattcaag
    30781 tagtagattt agcaatagga catataaaag ctttagaaaa agtatctgaa aaaacagatg
    30841 tttatatcta taacctaggc tcgggagaag gcactagtgt attacaactt gtaaatacat
    30901 ttgaaagtgt taataagatc cctattcctt ataaaatagt tccaagacgt tcaggagacg
    30961 ttgcaactta ttatgcaaat gcagacaaag catataagga attaaattgg aggacaacaa
    31021 aatcgattga agacatgtgt agagatacat ggaattggca atcaaaaaat cccaatggct
    31081 ataattgatg atactgtcta tatgagtgct gtattttgga aaaattactt aaccttttaa
    31141 tgaaagataa attaaaaaaa atatttgaca gcgcttgaca aaggaaacgg tttcattgta
    31201 taatgtaaac acaatgacac cgatgtcaaa tataaaaaag aaggtcttta tatgaaaaac
    31261 ttaacaaaaa ttaagttcaa agaaaatggg gaatttaatc atttccctgg gaatacagtt
    31321 gtagcaaatc tttatactaa acaagatttg atggaagttg ttgatattat tcaatcacgt
    31381 tatagagaat taccatttat cgataagttt actttaactc caaggaattc tattcacatg
    31441 actgtaattg aattgttgtg ccatgaaaat cgtgaaacgg agttttggag cagtaatctt
    31501 cctctagata cacctttaca ggaaatacat gattactttg ctaaacaact tgaaattttt
    31561 ccattgttgg atgaagaaat ttatatgcgt ataactgaaa tgggaaaaca aaacatacta
    31621 gttgaacctg cagatgaagc ttctgcaaag agattagaag aaattcgtac ttatgtctca
    31681 gaaaaagcag gtgtttgttt ccctaatcat gatagatatc aattccatat ttcaattggg
    31741 tatcttcgga ttcctctaac cgaagaggag gaagaagagt ttactaaagt cagagcagaa
    31801 ttaactgaaa ttttattaga gaagattcca actattactg taaaccgtat tgactatact
    31861 gtatttgaag atatgagaca atttgttcca tatcacgaaa aatttaaata aaataataaa
    31921 aaaggagaac ttatcatgaa aaaaatgaaa gtttggtcta ctgtacttgc aacgggagtt
    31981 gctcttacta cacttgctgc ttgctctgga ggttcaaatt ctacgactgc ttcttcatct
    32041 gaagaaaaag ctgataaaag tcaagaatta gttatctatt cgaactcagt ctcaaatggt
    32101 cgtggtgatt ggttaactgc taaagcaaaa gaagctggtt ttaatataaa aatggttgat
    32161 atcgctggcg ctcaattagc agaccgtgtt attgctgaga agaataatgc agttgcagat
    32221 atggtatttg gaattggtgc tgttgactca aataaaatta gagatcaaaa attactagta
    32281 cagtacaagc ctaaatggtt agataaaatt gatcaatctt tatcagataa agataattat
    32341 tataatcctg tgattgttca accattagtt ttaattgggg cgcctgatgt aaaagaaatg
    32401 cctaaagatt ggactgaatt aggtagtaag tataaaggta aatattcaat ttatggtctt
    32461 caaggtggta caggacgggc aattctagca agtatcttag ttcgttacct tgatgaaaaa
    32521 ggagatttag gcgtatcaga aaaaggatgg gaagttgcaa aagaatactt tgcaaatgcc
    32581 tatactcttc aaaaaggtga aagctcagtt gttaaagcgt tagataaaga aagcccaatt
    32641 caatacggta tgatctgggg ttctggagcg ttaattggac aaaaagaaca aaatgttgaa
    32701 ttcaaagtta tgactcctga gattggtgta ccatttgtaa ctgaacaaac tatggtttta
    32761 agcactagta aaaaacaagc gttagctaaa gaatttattg attggtttgg tcaatcagaa
    32821 attcaagtag aatatagtaa aaaatttgga tctattcctg caaataaaga tgccctaaaa
    32881 gagttacctg aagatacgaa aaaatttgtt gatcaagtga aaccacaaaa tattgactgg
    32941 gaagctgttg gaaagcattt ggatgaatgg gtagaaaaag ctgaattaga atacgtaaaa
    33001 taagaaataa gagttatttt ttatgtccaa gtctctctat tatttctaaa tttaaggaag
    33061 aaataaagag aggcttttgg ttttagtaat agagggagtt agtgagatga ttaaatttga
    33121 taatattcaa attaaatatg gtgattttgt tgcaattgat aatctgaatt tagatataca
    33181 tgaaggggaa ttctttacat ttcttgggcc ttcaggatgt ggtaaatcaa ctactttgag
    33241 agcattggta ggttttttag atccatcatc aggaagtatt gaagttaatg gaacagatgt
    33301 cactcatttg gaacctgaaa agcgtggaat tggtattgta tttcaatctt atgcgctatt
    33361 tccaactatg actgtttttg ataatattgc atttggttta aaagttaaga aggtagctcc
    33421 agatgttatt aaagctaaag tatcagcagt ggcagcaaaa attaagatct ctgatcaaca
    33481 gttacagcgt aatgtatcag aattatctgg gggtcaacaa caaagggtag cattggctcg
    33541 tgctctggtt cttgaaccta aaattctttg tctagatgaa ccattgtcaa accttgacgc
    33601 aaaattacgt gtagatttga gaaaagagtt gaaaagactt caaaaagagt taggtattac
    33661 tactttatat gttactcatg atcaagagga agccttgact ttatctgata gaattgcagt
    33721 ctttaacaat ggatacatcg aacaggtcgg tacaccagta gagatttatc ataattctca
    33781 aactgaattt gtatgtgatt ttattggaga tattaatgtt ttgaccgatg aaacagtcca
    33841 cgaagtatta ttgaaaaata caagcgtttt cttagaggat aaaaaaggat acattcgatt
    33901 agagaaagtt cgattcaatc gtgaaactga acaagatttt attctaaaag ggacaattat
    33961 tgatgttgag ttttctggag ttacaattca ctatacaata aaagtttctg aaagtcagat
    34021 tcttaatgta acaagtattg atagtcaggc tgctattaga tctgtcggag aaagtgtgga
    34081 attatttatc acaccatcag acgttctgca attttaagga ggtgcagtat gcgtcataaa
    34141 ttaaatttaa aagattggct tattcgttta gggttaatct ggttcttagt aacatttatt
    34201 atttatccaa actttgatct agtagtgaat gtatttgtaa aaggaggaga attttccctt
    34261 gatgctgtac atcgtgttct aaaatctcag agggcacttc agagtattat gaacagtttt
    34321 aagttagcat tttcactcat tattacagtt aatgtcgtag gtattctttg tgttctattt
    34381 acagagtgct ttgatattaa aggtgctaaa attttaaaat taggttatat gacctcttta
    34441 atttatggag gagtggtttt agcgactgga tataaatttg tctatggtcc ttatggattg
    34501 attacaaaat ttttacaaaa tgttatccct tctttagact ctaactggtt tattgggtat
    34561 ggtgcagtct tattcattat gacattttca ggaactgcta atcatacatt gtttttaaca
    34621 aatacaattc gaagcgttga ctatcacact attgaggctg ctcgaaatat gggagcaaaa
    34681 ccatttactg ttttccgaaa agtagtgtta ccaaccttaa ttccaactct atttgcactt
    34741 actattatgg tttttcttag tggtttatct gcagtagcag cacccatgat tgttggtggt
    34801 aaagaatttc aaactataaa tccaatgatt attacatttg cagggatggg gaattctcgt
    34861 gatttagctg ccttacttgc aattatttta ggtattgcaa ctacaatttt gcttactatc
    34921 atgaataaga tagaaaaagg tggaaattat atttctatct ctaagactaa agcgcctctt
    34981 aaaaaacaaa aaattgcgtc taagccttgg aatatcattg ctcacattgt agcatatgga
    35041 ttgttcacag ttttcatgct tccactaatt tttatagtat tatactcatt tacagatcca
    35101 gttgcaattc aaacaggtaa cttaacatta tcaaacttta ctttagaaaa ttatcgctta
    35161 ttctttagta atagtgcggc attctctcca ttcttggtca gctttattta ttctattatt
    35221 gctgcgacaa cagcaacaat tctcgcagtt gtatttgctc gtgttgtcag aaaacataaa
    35281 tctcgttttg atttcttatt tgaatatggt gctctacttc cttggttatt accaagtacg
    35341 cttttagcag taagtttatt atttactttt aatcagccac aatttcttgt cttgaatcag
    35401 attttggtag gtagtttggt aattctactt attgcatata tagttgtaaa aatcccattt
    35461 tcttatagaa tggtacgtgc tattttattt agtgttgatg atgagatgga agatgcagca
    35521 agaagtatgg gtgcttcacc tttttatact atgatgaagg ttatcattcc atttatttta
    35581 ccggttgttc tctctgttat tgctttaaac tttaactctt tattaactga cttcgactta
    35641 tctgtattcc tttaccatcc cctagctcaa ccattaggta ttacgattcg atctgcaggt
    35701 gatgaaacag caacatctaa tgcacaagct ctggtatttg tttatacaat tgttctgatg
    35761 attatttctg gaacggtatt atacttcaca caaagaccgg ggcgtaaagt aaggaaataa
    35821 tcatgacagc cactagtctt gggttatcaa atattgaaat agttgtcagg attgttttat
    35881 cagtagtcat tggtagtata attggtttag agagagggag caaatcccag cctgcaggca
    35941 tccgaactta tagtattgtt tgtctagctg catgtttgat tatgatgacg aatgagtacg
    36001 tatcttataa atttgggaca ggagatccta cacgattagg agctcaagtt atatcaggtg
    36061 tgggttttct aggcgctgga acgattctta ttacagataa aaagaaaatt acaggtctga
    36121 caactgcagc aggcatttgg gcttcggcag gaattggatt agctattgga gtaggttttt
    36181 atgagggagc tcttttagta gccatttctg tttggggtgt gatatccatg ttccaaccac
    36241 taaaaaaata tctgcaaaat cgttctaaaa tgattgaatt gtatatagtg gttaaatcta
    36301 cagaagccta taatcgtgta ttggtttatt gtgcagaaaa tggtatcaga atgaccgatt
    36361 caagaacagc gtttggagat gttaattctg acagaattga atactttgat gttccagaca
    36421 aaaaaatagc gtcatttatt actctggaat tatcaggtag atttgaacat cttcgactga
    36481 tggaagaaat tgctaatatt gtaggtgtta tttatgtcga agaaattagc tgaaatttag
    36541 taaacaaagg gacagatgtt tttgtccttt tgttttttag atgttttaat catctaattt
    36601 ttgagtagat ttttgctcag aggtttttat gaaagattat aaaatcaatt ttgatttagg
    36661 taaaatagaa tattttgata ataattgttt gatacaagta tacaaattta tttcttttta
    36721 tgatatttgt gaaatggtgt ttgcctttca tttacctcct gatgagttga taacaaatgt
    36781 tatctttaaa gaaaaaatta actct
//
LOCUS       DAVLUM010000010        36746 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLUM010000010 DAVLUM010000000
VERSION     DAVLUM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.010"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(502..1350)
                     /locus_tag="VYN42_000408"
     CDS             complement(502..1350)
                     /locus_tag="VYN42_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1461539.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            1502..1780
                     /locus_tag="VYN42_000409"
     CDS             1502..1780
                     /locus_tag="VYN42_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461540.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            1782..3845
                     /locus_tag="VYN42_000410"
     CDS             1782..3845
                     /locus_tag="VYN42_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1461541.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3923..5179)
                     /locus_tag="VYN42_000411"
     CDS             complement(3923..5179)
                     /locus_tag="VYN42_000411"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1461542.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            5321..7783
                     /locus_tag="VYN42_000412"
     CDS             5321..7783
                     /locus_tag="VYN42_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1461543.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            7848..8759
                     /locus_tag="VYN42_000413"
     CDS             7848..8759
                     /locus_tag="VYN42_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1461544.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            8989..9687
                     /gene="dapD"
                     /locus_tag="VYN42_000414"
     CDS             8989..9687
                     /gene="dapD"
                     /locus_tag="VYN42_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1461545.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            9755..10885
                     /locus_tag="VYN42_000415"
     CDS             9755..10885
                     /locus_tag="VYN42_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1461546.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            10897..11436
                     /locus_tag="VYN42_000416"
     CDS             10897..11436
                     /locus_tag="VYN42_000416"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1461547.1"
                     /translation="MKSELRKQVLQGMKAISQEQKQFIDQTLTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            11420..12097
                     /locus_tag="VYN42_000417"
     CDS             11420..12097
                     /locus_tag="VYN42_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1461548.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYMTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRLYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(12164..13063)
                     /gene="galU"
                     /locus_tag="VYN42_000418"
     CDS             complement(12164..13063)
                     /gene="galU"
                     /locus_tag="VYN42_000418"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1461549.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(13085..14101)
                     /locus_tag="VYN42_000419"
     CDS             complement(13085..14101)
                     /locus_tag="VYN42_000419"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1461550.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVAVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            14313..14694
                     /locus_tag="VYN42_000420"
                     /pseudo
     CDS             14313..14694
                     /locus_tag="VYN42_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(14868..15293)
                     /locus_tag="VYN42_000421"
     CDS             complement(14868..15293)
                     /locus_tag="VYN42_000421"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1461551.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(15361..16011)
                     /gene="phoU"
                     /locus_tag="VYN42_000422"
     CDS             complement(15361..16011)
                     /gene="phoU"
                     /locus_tag="VYN42_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1461552.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(16026..16778)
                     /gene="pstB"
                     /locus_tag="VYN42_000423"
     CDS             complement(16026..16778)
                     /gene="pstB"
                     /locus_tag="VYN42_000423"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1461553.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(16780..17595)
                     /gene="pstA"
                     /locus_tag="VYN42_000424"
     CDS             complement(16780..17595)
                     /gene="pstA"
                     /locus_tag="VYN42_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1461554.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(17588..18451)
                     /gene="pstC"
                     /locus_tag="VYN42_000425"
     CDS             complement(17588..18451)
                     /gene="pstC"
                     /locus_tag="VYN42_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1461555.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(18569..19444)
                     /locus_tag="VYN42_000426"
     CDS             complement(18569..19444)
                     /locus_tag="VYN42_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1461556.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(19611..20942)
                     /locus_tag="VYN42_000427"
     CDS             complement(19611..20942)
                     /locus_tag="VYN42_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1461557.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(20943..21650)
                     /locus_tag="VYN42_000428"
     CDS             complement(20943..21650)
                     /locus_tag="VYN42_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1461558.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(21734..22219)
                     /locus_tag="VYN42_000429"
     CDS             complement(21734..22219)
                     /locus_tag="VYN42_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1461559.1"
                     /translation="MAPTDKEDLIRTLELAPHIEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVVPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            22205..22762
                     /locus_tag="VYN42_000430"
                     /pseudo
     CDS             22205..22762
                     /locus_tag="VYN42_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23077..24768)
                     /locus_tag="VYN42_000431"
     CDS             complement(23077..24768)
                     /locus_tag="VYN42_000431"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1461560.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            24904..25350
                     /gene="argR"
                     /locus_tag="VYN42_000432"
     CDS             24904..25350
                     /gene="argR"
                     /locus_tag="VYN42_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1461561.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            25401..27935
                     /gene="mutS"
                     /locus_tag="VYN42_000433"
     CDS             25401..27935
                     /gene="mutS"
                     /locus_tag="VYN42_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1461562.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     VSSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKST
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            28082..29776
                     /gene="patA"
                     /locus_tag="VYN42_000434"
     CDS             28082..29776
                     /gene="patA"
                     /locus_tag="VYN42_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1461563.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(30106..30369)
                     /locus_tag="VYN42_000435"
                     /pseudo
     CDS             complement(30106..30369)
                     /locus_tag="VYN42_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            30567..32333
                     /gene="patB"
                     /locus_tag="VYN42_000436"
     CDS             30567..32333
                     /gene="patB"
                     /locus_tag="VYN42_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1461564.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            32472..33161
                     /locus_tag="VYN42_000437"
     CDS             32472..33161
                     /locus_tag="VYN42_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1461565.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            33165..33344
                     /locus_tag="VYN42_000438"
     CDS             33165..33344
                     /locus_tag="VYN42_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461566.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            33331..34680
                     /locus_tag="VYN42_000439"
     CDS             33331..34680
                     /locus_tag="VYN42_000439"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1461567.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            34804..36264
                     /locus_tag="VYN42_000440"
     CDS             34804..36264
                     /locus_tag="VYN42_000440"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1461568.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELVAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            36278..36676
                     /locus_tag="VYN42_000441"
     CDS             36278..36676
                     /locus_tag="VYN42_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1461569.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYW"
BASE COUNT        10714 a         7024 c         8048 g        10960 t
ORIGIN      
        1 ttggatttta tttgttattt tgacctgcct ctatattggt aaccatgatt tgtttactct
       61 caatcatcaa gaattctctt ttcgtggtag cgtttggggt ctggtactgg ccttatatca
      121 cttattgttc attgataagt ttgtaatttc gaatcgaaaa taaagattag aactatgatt
      181 gactggctac ttttaatatt gattttggag gaagattttg tctctattat ttattatttt
      241 aaatttatct attttgtaca agatttattc tttgagacgg gagaaatcga aatacttgat
      301 ttatacggcc tatatcatat ttggggtaaa tgtagtatat ggtattcaat ggttattaag
      361 agaactgatt tcaactattt ccccttaatg tgtatggaaa ctataacaaa acgcataaga
      421 ttaaggtttg tgtacctgtt cttatgcgtt tttataatat tgaagatttt cggtaagttt
      481 tatacctttg ggaagtctag tttagaatgc tttcccaacc aaaatctctg cttcgatggt
      541 aatctctgtc agttggctcc agtcaatctt gctctggtca acgtgaaaga ggagaggagt
      601 catactgagt agggcttgga gttgttctgc tgtgatagtc ttagtcagag aggcagtttg
      661 actagatagg atggtaaagt gttcctggaa atgctccttg atatcttggt tagaatactc
      721 cttgtttgtc agctggtcct gtactctttg acggatttct ttgaggtgat tttcagttgg
      781 gataaccttt atcaagatac cgtctttgga taaaacgcga cgaaattctc catagttggc
      841 aggtgagaag atatcaagca gaatatccat gttagcgtct tttataggaa gtcgtgccaa
      901 gtcgccaaca aaccaattga ctgcccagtt gggttcactt ttagcagcga tttggactga
      961 atctttggag atgtcaaagg catagaaagt tttttcagag tgactttctt gtagtttgcg
     1021 agaatagaat ccttcaccac aaccgatatc caaaattgtt gtggtagttt ttgagcttgc
     1081 aagcaagtca gatacagcat ctaagatagc ttggtaaaag ccggcttcta ggatttgttg
     1141 acggttttga aaattttcct tgttatagtt agcagattgc ttgatttgag gtgctagatt
     1201 gacatagcca aatttcgcca agtcaaaaga atgacggttg cagcacttga aattagtctc
     1261 taacagagtc agattttctt gacagatagg acaggcaaag gcagtcgcag aagcaaaacg
     1321 ctgaagtttg ggcttgagat ttgtattcat agtttaagtg tatcaaaaga ggcaaatgaa
     1381 agcaacttta ggaataagta gatgggagat tcagtagaaa taaaactaat tctccaattt
     1441 atagaatgaa attgctttta tatctaaatt gctatataat aatgataagg aggaaataag
     1501 tatgttaaaa gaagtattaa ccgttgcaaa agttgcgaaa aaatcttcat tatttttggg
     1561 tggtgtcgca tttggtaccc ttggtttgaa aatcttagca agtaaggaag ctaaaaaagg
     1621 ttattctaaa gctttggcta aggcttacaa gttgaaagac gagctagatg catctgtttc
     1681 tgttgtgaag caacatggag acgatgtctt gcaagatgcc aaatatttgt acgagcaaga
     1741 gaaaaaagaa gagcaattag atagccttat aggtgaataa tatgtctttt aaagtgctac
     1801 atagaggata ccaacatatc cgactatcat cttctttttc acttaccttg gatattcaag
     1861 actatcttcg ttccttggcg agagatgaaa aggggattga gtctatccag ttttacatgg
     1921 atcaacagca ctttactcta cgcataaaag aaggcttttc tgtattagat aatgcagaag
     1981 cctttttaaa aagaattgat aaagggaaag tttctgagtt gatgactctt cccattcgta
     2041 gagaagagag tgcttattct attgtttcag gtgcagcggt taagcgtgta ctttttcgta
     2101 gttttgtgcc gtatcctatt cgctatatat ggacttgtta tcaggctttg ggttatatta
     2161 gagaagccta tcaaacacta gcgcgtaagg aactaactat ggaagtcttg gactgttcgg
     2221 ctattttatt gtctttgttt atgaaccaat ccaagacagc tagcaatatc atgtttatgc
     2281 ttgatttggg gaatcattta gatcagtggt ccttgaaaaa aactgcaaca gatttagaac
     2341 agagtcttct tgcaaaagag agcgatgtat tcctagtaca gggcgatacg gttgttagta
     2401 taaagagttc cgatgttcaa ataggagatg tcttgatctt atctcaagga aatgaaattc
     2461 tgtttgatgg gcaagtagtt tcaggtttag gtatggtcaa cgaaagttcc ttgacaggag
     2521 agagttttcc agttgaaaaa agagagtctg atttggtttg tgcaaataca gtattagaaa
     2581 ctggagagtt acgcattcgt gtaacagata atcagatgaa cagccgtatt ttacagctga
     2641 ttgagttgat gaagaaatct gaagaaaaca agaaaacgaa acaacgctat ttcatcaaga
     2701 tggcggataa agtcgtcaaa tataatttct tgggggctgg gctgacttac ctattgacag
     2761 gttctttttc taaggctatt tctttcctat tggtcgattt ctcctgcgct ttgaaaatct
     2821 ctactcctgt agcttatttg acagttatca aggaggggtt gaaccgtgaa atggtgatta
     2881 aggatggaga tgttctggag aaatatctgg aagttgatac tttcttgttt gataagacag
     2941 gaacaatcac aactagttat cctatagttg aaaaggtgtt accttttgga gactatagtg
     3001 aggaagatat tctcagaatc agtgcctgtc ttgaggaaca catttatcat cctattgcta
     3061 atgccatcgt caagcaagct gagatagagg gaattgaaca tgaggaaatg catgggaaac
     3121 tccaatatat cgcaagcaag gggatcaaat ctcatataga tggccaacca gttcttattg
     3181 ggaattatgt cttgatgcag gatgagcaga ttcatatcag ttcagaacaa aatgctttaa
     3241 ttgaagagta caagagtcac tacaatctct tattcttggc ttatcaaaat gaattgattg
     3301 gaatgttctg cattcatact cctttgagaa aagaagcaaa aacagccttg gataaactta
     3361 aggcacaggg gaaaaaattg attctggcaa caggagacac cttgattagg acagaggaat
     3421 tagtcaaaga tttgcccttt gatcaggtct atacagactt gaaacctgat gggaaatttg
     3481 agttagtaga gaaactgcag aaagcaggtc acactatttt gatggttgga gatggattga
     3541 atgactcagc ggctttaact ctatcagata tcggtgtggt gatgaatgag agtgcagata
     3601 tttctaagca gatgagtgat atcttattgt tagataatcg tttggatttc ttccaagagt
     3661 tggattcgtt atcatcatct ttgcaaacac tcatcaagaa aaatattcaa gataccgttg
     3721 tcgtaaatag tagtttgatt ggctttggct tatttaattg gttcagtcct tcaaatctct
     3781 ctatcttaca taatctaaca accttgcgca ttgtcttgcg tagcttgtct attaaaaata
     3841 gatagatgag agttattaac agcaaaaagg agttaccttt ctcgaggtta actcctttgt
     3901 ttatagataa atgttgaata gtttagtaag tcaatacaaa gtattttttc ttcccacgac
     3961 ggataacagt cagttcattt tctaacttat cagcgtcact caagacatag tcaaggtctt
     4021 ggatgcggtc gccgtttacg tagatggctc cgttttggac gtcttcacgg gcttggcgtt
     4081 ttgagttaac tataccagat gagacgagca gttccacgat attgttatgt tcgtctgcct
     4141 gtacttggta gtttggcaca ccacgaagtc cttgtttgag ctctttgaca gaaaggtttt
     4201 tgatgtttcc tgcaaagagt tgctcagtga tgttaagtgc ttctttgtag gcttcttctc
     4261 cgtgaacaag tgtaacaact tcacgagcca agactttttg agccaagcgt tcgtgtggcg
     4321 ctgcttcaaa ttgtttacga atatcttcaa tctcatcaag tgacaagaaa gtaaagattt
     4381 tcaagaagcg aacagcgtca gcgtccatca cgttcatcca gaattggtac atttcgtatg
     4441 gagaagtctt ttcgggattg agccagacgg catttccttc tgatttacca aatttcttac
     4501 cagttgcatc tgtgattagt ggaacagtga taacgtgacc agtcttgtcc gccttacgac
     4561 gaagcaattc ggtaccagct gtcatatttc cccactggtc agaaccaccg atttgaagag
     4621 tgacattatg gtcttggtta aggacgaaga agtcgtaccc ttgcatgatt tggtaagcga
     4681 actcagtgta agaaattcct gtttcgatcc gttttttaac agattcctta ctcatcatgt
     4741 agttgaccgt gaagtatttt ccaatatcac ggaggaagtc aatgaagctg atgctgccaa
     4801 accagtcgta gttgttgacc atgacagcct tgttttcgcc attttcaaag tcaagaaaac
     4861 gagaaagttg tccttggata gacttgaccc agccatctac tgtgtctttt gtttggagac
     4921 tacgttcagc atctttgaag gacggatctc cgatgagacc tgtagcaccg ccaacgagcg
     4981 cataaggttt gtgacctgct agttgcaagc gacgacttgt caagattgcg acaaggtggc
     5041 ctaggtgaag gctgtcagca gttggatcgt agccagtata ataagaaact tgaccttctt
     5101 ctagggcttt acgcaaagct tcttcatcag tcgtttgaaa tatcaaacca cgctctttta
     5161 gctcatcaaa aatgtgcatg tgtcttttct cctttttaaa attattgttt ctacctattg
     5221 tatcacaaac ttgggcaata gcctagcaga atagggaaga aagtggctat tttattgaaa
     5281 atttcccttt tgtggtataa tagatagagt gaggaaatcc atgcaaaatc aattaaatga
     5341 attaaaacga aaaatgctgg aatttttcca gcaaaaacaa aaaaataaaa aatcagctag
     5401 acctggcaag aaaggttcaa gtaccaaaaa atctaaaacc ttagataagt cagccatttt
     5461 cccagctatt ttactgagta taaaagcctt atttaactta ctctttgtac tcggttttct
     5521 aggaggaatg ttgggagctg ggattgcttt ggggtacgga gtggccttat ttgacaaggt
     5581 tcgggtgcct cagacagaag aattggtgaa tcaggtcaag gacatctctt ctatttcaga
     5641 gattacctat tcggacggga cggtgattgc ttccatagag agtgatttgt tgcgcacttc
     5701 tatctcatct gagcaaattt cggaaaatct gaagaaggct atcattgcga cagaagatga
     5761 acactttaaa gaacataagg gtgtagtacc caaggcggtg attcgtgcga ccttggggaa
     5821 atttgtaggt ttgggttcct ctagtggggg ttcaaccttg acccagcaac taattaaaca
     5881 gcaggtggtt ggggatgcgc cgaccttggc tcgtaaggcg gcagagattg tggatgctct
     5941 tgccttggaa cgcgccatga ataaagatga gattttaacg acctatctca atgtggctcc
     6001 ctttggccga aataataagg gacagaatat tgcaggggct cggcaagcag ctgagggaat
     6061 tttcggtgta gatgccagtc agttgactgt tcctcaagca gcatttttag caggacttcc
     6121 acagagtccc attacttact ctccttatga aaatactggg gagttgaaga gtgatgaaga
     6181 cctagaaatt ggcttaagac gggctaaggc agttctttac agtatgtatc gtacaggtgc
     6241 attaagcaaa gacgagtatt ctcagtacaa ggattatgac cttaaacagg actttttacc
     6301 atcgggcact gttacaggaa tttcacgaga ctatttatac tttacaactt tggcagaagc
     6361 tcaagaacgt atgtatgact atctagctca gagagacaat gtctccgcta aggagttgaa
     6421 aaatgaggca actcagaagt tttatcgaga tttggcagcc aaggaaattg aaaatggtgg
     6481 ttataagatt actactacca tagatcagaa aattcattct gccatgcaaa gtgcggttgc
     6541 tgattatggc tatcttttag acgatggaac aggtcgtgta gaagtaggga atgtcttgat
     6601 ggacaaccaa acaggtgcta ttctaggctt tgtaggtggt cgtaattatc aagaaaatca
     6661 aaataatcat gcctttgata ccaaacgttc gccagcttct actaccaagc ccttgctggc
     6721 ctacggtatt gctattgatc agggcttgat gggaagtgaa acgattctat ctaactatcc
     6781 aacaaacttt gctaatggca atccgattat gtatgctaat agcaagggaa caggaatgat
     6841 gaccttggga gaagctctga actattcatg gaatatccct gcttactgga cctatcgtat
     6901 gctccgtgaa aagggtgttg atgtcaaggg ttatatggaa aagatgggtt acgagattcc
     6961 tgagtacggt attgagagct tgccaatggg tggtggtatt gaagtcacag ttgcccagca
     7021 taccaatggc tatcagacct tagctaataa tggagtttat catcagaagc atgtgatttc
     7081 aaagattgaa gcagcagatg gtagagtggt gtatgagtat caggataaac cggttcaagt
     7141 ctattcaaaa gctactgcga cgattatgca gggattgcta cgagaagttc tatcctctcg
     7201 tgtgacaaca accttcaagt ctaacctgac ttctttaaat cctactctgg ctaatgcaga
     7261 ttggattggg aagactggta caaccaacca agacgaaaat atgtggctca tgctttcgac
     7321 acctagatta accctaggtg gctggattgg gcatgatgat aatcattcat tgtcacgtag
     7381 agcaggttat tctaataact ctaattacat ggctcatcta gtaaatgcga ttcagcaagc
     7441 ttccccaagc atttggggga acgagcgctt tgctttagat cctagtgtag tgaaatcgga
     7501 agtcttgaaa tcaacaggtc aaaaaccagg gaaggtttct gttgaaggaa aagaagtaga
     7561 ggtcacaggt tcgactgtta ccagctattg ggctaataag tcaggagcgc cagcgacaag
     7621 ttatcgcttt gctattggtg gaagtgatgc ggattatcag aatgcttggt ctagtattgt
     7681 ggggagtcta ccaactccat ccagctccag cagttcaagt agtagttcta gcgatagcag
     7741 taactcaagt actacacgac cttcttcaag ggcgagacga taattctcta aatgaagtgg
     7801 ccaatcaatg gattgccact tttttccttt cgtgttacaa taagggtatg aatcagtatc
     7861 agaaaaagat tgttaacgga aaaatttatt cgctcctatc cggcttaata tggggaatct
     7921 gtggaatttt aggagagtac ttctttactc attatcaggt gtcttcgggc tggattacct
     7981 ctatgcgttt gacactggca gggagtcttg tactcatttg gtctgcaata caattaaaat
     8041 cgcaagtgct agatatttgg cgagacaaga aaaattacct gcccttttta gcctatgcta
     8101 ttttggggat tttttcagtt cagtattttt tctatctctg tgtagaatac tcaaatgcta
     8161 cgacagcaac tattttacag tttattagcc ctgtctttat cctcttttat aatcgcttgg
     8221 tttatcaaaa acgagcgtca aaaagcgctg ttttctatgt tttggttgcc atgctgggtg
     8281 tttgcttgat ggcgacaaag ggagatctct ctcagttatc catgacgccg ctagctctta
     8341 taacaggttt gctgagtgcc atgggtgtta tgtttaatgt tatcttgccc caaccttttg
     8401 ctaagcgtta tggttttgtt cctacggttg ggtgggggat gattttggca ggtttgttta
     8461 gcaatgtcct ctcgccggtt tatcagcttt cctttactct tgatatttgg agtatcttga
     8521 tttgcctcat tatcgctttc tttggaacgg cttttgcttt tttcatttcc atgaaggctg
     8581 tgtccttggt ttctcctttg gtggtttccg ttatcagtgc cagtgaacct ctctcttctg
     8641 ctctcttgag tgttttgttc ttaggattag tagtggattg gtccctcctt ctagctatag
     8701 ccttgattat tttacccatg atatttttgt ctatagaaga agcgaaagaa agtagataaa
     8761 aagtcttttc ttaattctaa aagtgtgcta tactagaata gtcaataaaa cacggggaga
     8821 tagttgtgaa gagtgttttt aggttgtatc ggtaggggct tgcttttacc gacagcacgt
     8881 tttatctcac aaccctaaaa aatcatacct aaaaacagac aaaaaggttt caaatttgag
     8941 gccttttttg gtagaatagg tatcattata acgaaccagg aggcacctat gactgctaca
     9001 aaaatgaacg ctcaagaaat tatccaattt atcgccaatg ctgaaaagaa aaccagtgtc
     9061 aaagtaacct ttgaggggca actcgcaact gctgtgccta gctctgttgt caaactagga
     9121 aatgtcctat tcggagactg gaaggacgtg gctccgcttc ttgaaggttt ggtagaaaat
     9181 caagattatg ttgtcgagca agatgctcgt aattctgcag ttcctttgct agataagcgt
     9241 gctatcaacg ctcgtatcga gccaggtgct attatccgtg accaggtgga aattggtgac
     9301 aatgctgtta tcatgatggg agctgttatc aatatcggtg ctgaaatcgg tgctggaacc
     9361 atgattgaca tgggtgccat ccttggtggc cgtgctatcg ttggaaaaaa tagccacgtt
     9421 ggtgcaggtg cagttttggc aggtgtgatt gagccagcta gtgctgaacc agtccgtgtc
     9481 ggagacaatg ttcttatcgg tgctaatgca gtggttatcg aaggagtcca aatcggtagt
     9541 ggttcagttg tcgctgcagg agctatcgtt acccaagatg tcccagaaaa cgtggtagta
     9601 gcaggtgttc cagctcgtat catcaaagaa attgatgccc aaacccaaca aaaaacagcg
     9661 ctagaggatg cgcttcgtac cttgtaattg taaaagtaaa aaagaggcgg aacccttttt
     9721 ccagcctctt tctgctatat cggaggacag atagatgtta gatttgattc agactagacg
     9781 agctttacac cagattccag agattggctt ggaggagttc aagactcagg cttatttgct
     9841 ggatgtgatt gagaaattga ctacgggcaa ggattttgtt caaattcgta cttggcggac
     9901 agggattttg gtctacctgc agggaagtca gccggagcga accattggtt ggcggacaga
     9961 tattgatggc ctgcctatcg tcgaacaaac aggtctacct tttgcttctc aacaccaagg
    10021 tcgcatgcat gcctgtggcc atgattttca tatgaccatt gccttaggct gtcttgagcg
    10081 cgcccttgag gagcaaccca agaataatct gctctttcta tttcagcctg ctgaagaaaa
    10141 tgaagctggt ggtatgctca tgtatgagga tggtgctttt ggagattggt tgccaaacca
    10201 attctatggt ctccatgttc gtccagattt gaaagtcggc cagattgcga ctaatactca
    10261 tacactcttt gcaggaactt gcgaggtgaa gatccgtttc aaaggcaaag gtggccacgc
    10321 agcttttcct catgaagcca atgacgcctt ggtggcggct agttactttg tgacccaagt
    10381 gcagtcagtt gttagccgca atgtcaaccc aatcgaggga gcagtggtga ccttcggcgt
    10441 ttttcaagct ggaaccacca acaatgtcat cacagacaca gcttttttac atggaactat
    10501 tcgtgccttg acacaggaca tgagtctctt ggtgcaaaag agggtaaaaa cagttgcaga
    10561 aggggttgca gctgcctttg atatggaagt cgaagtggaa ctcaaacaag gtggatacct
    10621 acctgttgag aacaatccag ccttggcgcg tgaactgatg gacttctttg acgaaaaaga
    10681 cggaatcgag ttgattgata tcgaacctgc tatgacaggc gaggactttg gttatctcct
    10741 ttcaaaggtt gatggcgtga tgttttggct aggtatcgat agtccctacg ctcttcatca
    10801 ccctcaaatg agtcctaagg aagaagtctt agctattggg gtggctgcgg tgtctagttt
    10861 cctgaaaaag aaggcagcag aatagagggc ttgtctatga aatcggaatt acgcaagcaa
    10921 gtcttgcaag gaatgaaggc tatatctcaa gaacaaaaac agtttataga tcaaacttta
    10981 accgagcggc ttttacacca tcccttctat caagaagcca aggtcatcgc aacctacctc
    11041 tctttttctc atgagtttca aacgcgggaa ctgattgagc aggcgctgaa ggacggcaag
    11101 aaggttttaa tacccaaaac ttatcccaag gggcgcatgg actttgtagt ctatgatctg
    11161 cagcagttgg taaaaactgc ctttgcctta ctggagccac agggagattt ggaagtggtg
    11221 gatgtatctc agattgattt gattcatgtt cctggcctgg cttttacgac ggatggatat
    11281 cggattggat atggtggagg ttattatgac cgctatctgg aacatttttc tggtcatact
    11341 ttgagtacgg ttcatccttg tcaaattcag gactttatac ctgaaaacca tgatattcct
    11401 gttcaggagg tattaattga tgaaggaaat ctttgataga cgttaccctg tgacgagttt
    11461 cttcctctta gtgacggcct tggtattttt actaatgttg gtcactgcag gcgggaactt
    11521 tgacagggca gatacattat ttcgatttgg agccatgtat gggccagcta ttcgcctctt
    11581 tcccgagcag gtttggcgtc tcttgtctgc catttttgtt catattgggt gggaacattt
    11641 cattgttaat atgctttcac tttattatct tggaaggcag gtagaggaga ttttcggttc
    11701 taagcagttt ttctttctct atcttttatc aggaatgatg ggcaatctct ttgtttttgt
    11761 atttagtcct aaatccttag cagcaggcgc ctctacctct ctttatgggc tatttgccgc
    11821 gattatcatt cttcgctatg caacgcgtaa tccttatatc cagcagttgg gccaatccta
    11881 tatgacactt tttgtggtta acattattgg aagtgttctg attccaggga tcagcctagc
    11941 aggccatatc ggtggagcag ttggtggcgc atttctagca gttatctttc cagttagagg
    12001 agaaaaacgg ctgtataaca ccagccagag attaggagcg gtagtcttgt tcgtaggact
    12061 cgccattttg cttttctaca agggaatggg aatgtgacga agttgaaaga aaatttgtgt
    12121 aatgaaaaaa gataaggcat tttttgaacc ttatcttttt attttattcc ttctcagtca
    12181 attcttttcc aagttggatg aggtaattct tcaaatcatc tttgacttgt ggatgtttga
    12241 gggcgtagtc aatagatgtt ttcataaagc caaacttatc cccaacgtcg taacgagctc
    12301 ctgtaaattt acgggcaaaa acacgctgtg ttttattaag agtatcgatt gcatcagtaa
    12361 gttggatttc atttccagca ccaggagctt gcttttcgag aatctcaaaa atttctggtg
    12421 tgagtagata gcgaccgatg attgccaaat cacttggagt ctcctcggga gctggttttt
    12481 caacaaaggt ttcaacactg taaagaccat cttttccttc gtcttgagga gcaatgactc
    12541 catatgatga aacgtcttcg tgtggtacgg gcatgacagc aatggttgat gcgtgtgtct
    12601 tttcgtaatc attcatcagt tgttttgtca aaggaacggc cttctcgtct gtgatgtcca
    12661 tcaagtcatc acccagcata acaacaaaag gttcatttcc tacaaaagct ttggcttgta
    12721 agacagcgtc tccaagacca cgagggtgag tttggcggat gaaatgaagg cgcatgccag
    12781 ttgcttcatc taccaatttt aacaaatccg ttttgccttt ttccttaaga ttgtattcaa
    12841 gctcaaagtt tgaatcaaag tggtcctcaa tagaacgttt tgatttacca gtgacaacta
    12901 gaatatcttc aatacctgat ttgagagcct cttccacgat aaactggata gttggtttgt
    12961 ctacgattgg caacatttct ttggcaaggg ccttggttgc tggtaaaaat cgagttccta
    13021 gtccagcagc agggataact gcctttctaa cttttgatgt cataaaaatc ctttctatag
    13081 agggttaaga ccactcattt tctgctttaa attcattgtt catgatgtca taaatggcat
    13141 ctttgatatt ggttccgtga taaataactt ggtaaatagc ctgtgtaatg ggcatataga
    13201 ctccaagttc ttgggctagt tcataggctg ctcgagtcgt tgaaattcct tcgattacca
    13261 tgcccatatt agcttctata tcagctaggg attctcctcg tccgagagca tctccagctc
    13321 tccagttacg agagtggatg gaagttcccg ttacgatcaa atctcccaca ccagataagc
    13381 cgctataggt caatggactg gccccgagtg ctacccctag gcgggtgatt tctgctaaac
    13441 ctcgagcgat gatggctgcc ttagcattat caccaaatcc aagaccatgt aaagctccag
    13501 caccgacagc aataatattt ttaagagcac cagcagtttc aaccccgata acatccgtat
    13561 tggtataaag tcggaagtag tgattactaa atagctcctg aacgtattga gctgtttgta
    13621 aatctttaga agcagcagtt attaaagtta ggtcacgcac aatggtctct tctgcatgac
    13681 taggccctga aacagcgacg atatcactac ggagatgttc aggaatttct tcttcaagaa
    13741 tggttgataa tcgtttatgg ctatcaggtt ctaatccctt tgatgcgtgc atgatgataa
    13801 ccttatggtc caaggtttgt gcaacttgct gggcaacaag tcgtgtcact tttgttggga
    13861 caacaaacaa aatcgcatcc acatttttca atgtttctgc taagtcggtg taggcaatga
    13921 tattttcgtc tagaacgaca tctttaaagt agtgcttatt agtatggtgt gtattaattt
    13981 cattgatttg ctcgggaaga tttccccaaa tacgtacctc gtgtccattg tcatttaaga
    14041 cttgtgaaag ggcggttccc caagaaccag gccccaagac ggcgacggtt tgtttttcca
    14101 tgatttcctc cttgatagat ttctttctct tattctatca tattctaggg gattttgcac
    14161 ttgcattact ggggtatggt ggaaaaatac acaaagaccg agatgaaggg ataaactctt
    14221 agtctttagt taaagtgaga agaaatctga tagatagttt gattcagtat atgcttataa
    14281 tagaggtaaa caactcagga agttcttgta ggttgcgaga gtttggcgaa aaaattaaaa
    14341 gattacgttt ggctaaaaaa atcagtcgtt cagaattttg tggtgatgag tctgaattaa
    14401 gtatccgtca attaattaga attgaaaatg gagaatccag accaatacta acaaagttaa
    14461 aatatattgc tgaacgtttg gaggttgaag attacaagtt gatgccaagt tatatagagt
    14521 tggataagga atacctagaa ttgaagtatt tcttgatgag gactcctaca tacgaagatg
    14581 aaactatcac ccaaaagaaa gagagtgttt ttgataagat ttttgaagag tattatgata
    14641 ggctacctga ggaagaaaga tttatcatcc caaattattc atatctggca ctaacgaact
    14701 acacagttca aaaattacca gaaaagctag ttgaaatact gtccttctgg tgattttgct
    14761 taatttctga tgttcgagac atgattgagg agatttgtct tgattttttc ctaaaaaagg
    14821 gcagactcct cccttggttt gatgctcgat ttttaaaata aggtgactta ttctgttagg
    14881 catgttttcc cctgccctct agctctatat ggaacaggga gtatcagatt tatctggcag
    14941 attgtatcaa ataaggcttg aaactgtttt gaataggcat atagacttga gaatttgaga
    15001 atatgtcgtc tagcagtaga gacatatttt ccggcaatat gaaggaagag acgtcgaaaa
    15061 cgcttgatag tcaaggcctt tacttcatca ccagctagct gctttaaaaa gaggtagaga
    15121 ttataagcca gacagcccat catcatacgt acttcattct taatcatggt cgaactatct
    15181 gtcttatccc caaagaatcc tgctttcctt tctttgataa agttttcagc attccctcgt
    15241 tcacgataga attgaaacag ctcctcacta tctacactgc ttaaattggt caaatgaact
    15301 tttttacaac cataaaaaag agcacttaat cgtactcttc tcttttaagg attagttgaa
    15361 ttaattcaaa tccactagtt ctcctgtttc taggtagact aggcgttcac aaatgttagc
    15421 aatgtaatca gcgaagcgtt ccagatgccc tatgatataa aggtattgag ttccattggg
    15481 aattgaggtt tcttggtctt tcataagtcc aatgatttcc tttgataagg cataataata
    15541 ttggtcaatc tgttcatctt tttgagcaat actaatagct tttgaggctt ggtgcaaagg
    15601 aaaggcaacc aataaatcgg ctagcatgct gagggataat ttacccattt ggtgtaactg
    15661 ttcttcgtca ggggctagtt gattttcttt tagttgcaaa acagctttgg caatgcctgc
    15721 catatggtct cccatacgtt caaggtctga acaagaagac atgatgctaa tcacaaatcg
    15781 aaggtcagac acttgtggct gctgcaaggc taacaaacgg gcacaggtca attcgatagc
    15841 gctttgacct tggttgatag catgatcctt attgataatt agctctgcca tctccttgtc
    15901 tttggaggct aaggccagta aggcttttga agctgtttca aggacaagtt gccctagtcc
    15961 taaaaaggat tgttctaatt catgcaattc taagtcaaat tgatttctca taggtttttc
    16021 cttccttatc cgaaccgtcc tgaaatatag tcttctgtgc gctgatcttt tggattggta
    16081 aacacgtcaa cggtatctcc aaattcgcaa atttctcctg ttaagaaaaa agcagtttta
    16141 tctgaaatac gtgaagcttg ttgcatgtta tgggtaacaa tgataatcgt ataatccttt
    16201 tttagttgct gaatgaggtc ttcaattttt aaagtggaga tagggtctaa ggctgaagtc
    16261 ggctcatcca ttaacagaat atcaggttct actgctaaag ctcgcgcaat gcaaaggcgt
    16321 tgctgctgac cgccagataa ggacatggca ctctttttaa gatcgtcttt gacttcttcc
    16381 caaatggctg ccccttttaa agatttctcc actaaggcat ctaattgttt tttgtctcga
    16441 ataccatgtg tccttggacc ataagccacg ttatcataga tagacatggc aaagggatta
    16501 ggctgttgaa aaaccatccc tacacgcttg cgtagctgat taaggttgaa tttgctacta
    16561 taaatatctt gctcatctaa gaggacttgg ccttcaatat ggcaagaagg aaccaaatcg
    16621 ttcatccgat taagggtttt tagaaaagtt gatttgccac aaccagatgg gcctatcaag
    16681 gcagtaatct gtctttctgg taattgaatc gaaatatttt ttaaggcttg aaaatccccg
    16741 taaaataagt ctaggtgtct aactgaaaat gttcccatac taggaagctc ctttcacaag
    16801 ttttcgagat aataagcttg atagagtatt tatcattaaa acagtaataa tcaaaatcac
    16861 accggtagca taggcttcat tgacatgtag cccctcactt gacagcatat acatatgcag
    16921 ggctagagaa cgacctgaag acatgagact acttggcgta ttggtagagg tacctaatgt
    16981 atacatgagg gcagctgtct caccaacgat acggccaata gctagtatca ctccagctaa
    17041 aatacctggc atggcaactg gtagaacaat tctaaaaaca gtccgtaact tacctgcccc
    17101 aagtccataa cttgcttgac gcatgctatc actaacagat aaaagggctt cttctgttga
    17161 gcgaataatg actggcaaca ccatgatgac tgaggttaag attcctgata acagagagta
    17221 ttgaaaacct aagaagacta caaagaagag catgccaaac agaccaaaaa caatggaagg
    17281 aatcccagac aaggtatctg aggccaatcg catgatttta acacaaaggg aatctttttt
    17341 tgtatattcc acaagataaa aaccagcaaa aatccctatg ggcaaggcta aaagaagagc
    17401 accaaagacc agaataacgg tggaaataat cgctggcata agggaaatgt tctcagaagt
    17461 ataagtccaa gaaaagaggg atagacttag atgaggtaag cctttgatga ggataaaacc
    17521 aatgattaaa aagagagagc caaaggttaa agctgaaaaa caataaacga gaagttttag
    17581 caggtattta ctcataagat gattttcctt tcaagtaggc aaagtaggca ttaatcaaga
    17641 gaataaggaa aaagagaact gctgaggttg caataagggc ttccctatgc tgacctgatg
    17701 cgtaagccat ttccagaaca atattggttg ttaaggttct ggttcctgaa aagagtccac
    17761 ttggaataat cggctggttg cctgccacca aaataactgc catggtttca cctactgcgc
    17821 gaccgattcc taaaataact gctgataaaa taccagatct cgcagctggc aagatgacac
    17881 taaaaatact ccgttcatga ctagctccta gagccaagct accagaataa tacgttttgg
    17941 gaactgttcg gatagcagat tctgacaaac tgataatggt tggcaaaatc attattccta
    18001 atagtaacga agcggttagg acactcatgc catttcctaa aaaggttcta atccaaggca
    18061 ccaataattg taggccgaaa aaaccataaa caatagatgg aatggccgcc atcaagttga
    18121 tagctgattt taagaagcca tagacgggct ttggacaata ataaaccata aacaccgatg
    18181 tcaagatgcc tgttggcacc ccaatcacaa tcgctcctaa ggtaattaat aaggaaccaa
    18241 cgatcattgg taaaatacca tagcttgccg gaatgttcgt tggcgaccaa tcactgccta
    18301 ataaaaaacg ggcaaagccg tagttagcca tgaaaggtaa gccattacta aaaataaaga
    18361 aacagattag caaaatagct acaacagcta ctgttgcact catgaaaaaa attgccctaa
    18421 aaactgcttc tttgaaggct tgttttatca catcttgtcc tttctagtga agaaagtaag
    18481 ggagatacga cacctcccta cttgccttct ttatcttatt gtacgatgaa acgtctgcat
    18541 ctctttagag atttatggag caaacatttt atttaatctt gtcccaggtg gttaatttgc
    18601 cactaaaaac gtctgcaagt tcagccatac tgacttggct tgccttattg tcattattga
    18661 ccacaacagc aataccgtct aaagcaatag catcatgggt gagactctta ccttcttcag
    18721 gagttaattc cctagaaacc ataccaatat cagcggtttt ctccttaaca gcggtaatac
    18781 ctgctgaaga tccattagag gtaatatcaa tcgtaacttc tggattttct tttttataag
    18841 cttctgctaa tttttccatt aaagaagata ctgaagtgga acctacaaca gacaacttgc
    18901 ctgataagtg ttggcttgta tattctgtgg tttcggtttt agcttcaata aatttattat
    18961 ctgtgaccac ttgttgacct tgtttggagt ggataaagct gataaaatct tgacctagct
    19021 tggaaagatt agaagaccaa acaatgttga agggacgttg aagagggtat tcaccatcta
    19081 aaactgtgtc tcgactagcc ttgacaccat caatctctaa agccttgaca gatttcgtta
    19141 aagatcccaa ggagatgtag ccgatagcat tagcattccc ttgaactgct gagagaacac
    19201 cttctgtact attttgaatc acagctgttt tggcagtgtt gtcaattttt ttatcaccgt
    19261 cttttttgag aatccctgtg atttctgtga aggcaccccg tgttccagag ccattttctc
    19321 gtgaaatcac ctcaatcgtt cctgaagctg actgtttgga agcagctgac tgattgccac
    19381 aggcaacaag cccaaatcct gataagccaa tggctgcaag agtaagcatt tttttgaatt
    19441 tcataataat cacctttatc tctatgtatt tttcttgtgt aggcttacta catttatagt
    19501 ctaacaagtc tttgtaaagg tttatccctg attcatgtaa agattgtgta aagaatcaaa
    19561 aaaagccact tttgaaaaat ggctgctcct aaaaatagct ttaaaaatta ttagtcctgt
    19621 gcgaaagatt ggttaggaag aaaaatcgtg aagcaactgc ctctgccaag ctgactcgtc
    19681 accgtgactt ggccacctaa taattgactg agttctttga caatggcaag gccaagacca
    19741 gtgccaccag tttgtctgct tcgaccttta ttaactcggt aaaaacgttc aaaaatacga
    19801 tcctgctcta attgactaat accaatccct gtatctgata cagaaatctt aatgccttcg
    19861 ttcacctttt gggtcttgac ctcaattttt cccccttgtt cagtgtaacg gatggcattg
    19921 gataaaagat tgagtaagat ttgggaaagt aattgactat ctgatacgag ggtgacatca
    19981 tctggcacct gcacctttag ctgtaaatcc ttcttcttga gctgaggttg caagctttga
    20041 gtcaaatcct gtacaaattc tgccaaagaa agggtcgtcc attgtatagg catttgttga
    20101 gccttagata aggtaagaag atgctcaaca atatgctcaa gacgcaaact ttctttgtaa
    20161 ataatgtcta gaaagtcatc cttgagcgct tcttcttcag ctgacatccc cttaatggtt
    20221 tcagcaaagc ccttaatcga agtaactggt gtcctcaatt catgggaggc atttgagaca
    20281 aaggctaaat ttaacttttc ataagttcta atcgttgtta aatcatatag caagacgagc
    20341 acagcttcca cagattgggt ggggctaaaa acgggaactg ctgtcacttc taaaatcaag
    20401 tcaccctcat gaaacccact tacttcttgt tttaaccttg ttttttgatc aaaggcttgg
    20461 tgaactaaat tccgaatatc catccgtttg aggtcatcaa gtgaacttat gtcgccgtcc
    20521 acatcgggaa aataatgagg cagagagcga ctggataata acatctgacc ttgagcggaa
    20581 actaaaaacg tccccatggt taggtgcgac agaagaacct ccattgtttc ggctagatcc
    20641 ttgtattgct gatcctgttg ggagactttg gtttttaggc cagacacata ctgagccaaa
    20701 gactttaagt cttcttgccc tttttctaaa aagtattcac tactggtcaa gagaggttgg
    20761 tgcaaggtct caaaagcaac ttcccatttc caaaggcaaa agagccagta gccacctagt
    20821 cccaaagaaa gggctagaag aaagagaccg atgcctttac tgatccaagt taatgccatc
    20881 cctgcaatca gaatgaggct aacacttaga ttgactagcc aaaattgaag gtagcgtttc
    20941 atctataact ccttgaactt ataaccataa ccccgaatgg ttcgaataaa ttgaggggct
    21001 ttaggattgt cttcaatttt ttccctcaac ttaccaatat gaacgtccac caaacgtgtt
    21061 tcctgcccaa agtcataccc ccagatacgt tccaaaagac gctctctagt cagtgtcatg
    21121 ttgggatgtt tcataagata gagcaagagt tcaaattctt ttggggtcaa actcagtaac
    21181 ttattcgcct tgtagacttc atgacgctca gggtatactt tcaaggtccc aaatagccaa
    21241 gaatcgtcag cgatattatc tgaatcatct ccttcttgtt ctcctttagt tcgcctgagg
    21301 acagccttga cacgcgccag caattctcta gggctaaaag gcttggtcag gtagtcatca
    21361 gcccctaatt ccaaggccaa aaccttatca aattcatcac ttttcgcaga aaccatcata
    21421 attggagttt tgacgccttt ggctctcagc cgcttacaaa cttccatgcc atctaattgt
    21481 ggtaacatga tatcaagcaa gataaaatca aagggttctg tttctgccaa agctaaggcc
    21541 ttccgtccat ttgtcaccaa ttgagtagaa aagccttcct tacttaaatg gtagtcaagc
    21601 aatttcagaa tgtgttcttc atcatccact aataagactt gttttgtcat ctattatctc
    21661 ctattggtaa cattataaca caattatcag aaatcctaac attgctaaat cagattaaat
    21721 ttgcctatca agactagtat ctggtcaaac gctcaatcat ctccttgtgc tctggatagg
    21781 tcgccagtag atctaccctt tcaaataatt caaaatcctc aaattcaaaa ccaggaacaa
    21841 caagacaaga aaccagagca tcatccttat caactgttga tccccaaata gtgcccttag
    21901 gaacacagta gtgaagttgt tgccctttgg atatgtccag gcctaaagtg actgcttcgt
    21961 agtgaccatc tgctgtaatc atgtgaacag taagtgggga tcctgcatga aaataccaga
    22021 tttcatctgc tgtcaatcgg tgaaaatgtg aaggattcgt ttcttctaat aagaaataaa
    22081 tactggtata aagcgccctt cccttaccag caaggtttat agtgtctgaa gctttttttg
    22141 tttgtctaaa atagccacct tcaatatggg gagctaactc tagagttctt atcaagtctt
    22201 ctttatccgt cggagccaat gggttgaagt aactcttgtt caaagtggtt ttacgatttt
    22261 aagaactcct ctcagttctg aggacacggt aatgattgat gcgacggaag tacaaatcaa
    22321 tcgccctaaa aaaagaatta gcgaattatt ctggtaaaaa aaatgccacg ctatgaaggc
    22381 tcaagcgatt gtcacaagtc aagggagaat tgtttctttg gatatcgctg tgaactattg
    22441 tcatgatatg aagttgttca aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt
    22501 ggctgacaat ggttatcaag ggctcatgaa gatatatcct caagcacaaa ctccacgtaa
    22561 atccagcaaa ctcaagccac taacagttga agataaagcc tataaccatg cgctatccaa
    22621 ggagagaagc aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tgatttcaac
    22681 aacctatcga aatcatcgta aacacttcgg attacgaatg aatttgattg ctggcattat
    22741 caatcatgaa ctaggattct agttttgcag gaagtctatt atttggttag gtgaattagt
    22801 gaagcgttta ggcaagtgtc tctggttacg acgtcatgga ctctaaatcg attatattta
    22861 ggggtcatga ctagtgaagc agttagctag ttcgcatata agcggctagc gtctaacaat
    22921 taggaacttt agttccaata actttaagat tacgacgttt taggacataa atcgatcata
    22981 tttatgtcct aaaactagtg aagcgcctag ccaaagtccg aataggattt ggcgttagtt
    23041 acttagattg ctttgcaatc aagtaacttt ggcgatttac atcttctctg gcgcttctac
    23101 tccaagcaag cgaagggctt ctttgagaac gactgcggtt gcgtagctga gggctagacg
    23161 gctgtcgcgt tctgggcttt catccaagat acgtgtatgt gcatagtatt tgttaaagga
    23221 ttgagccagg ctaattgcaa atttagcaat gatagaaggt tcaaagttat ctgccgcacg
    23281 gttgataata cgtgggaagt cttgaatgag tttaatgatt tcccagcttt cagtatcatt
    23341 caagctatag ttgccagctg tttctggttt gaaatcggct ttgcgtaaga tagattggat
    23401 acgagcgtag gcatattgaa cgtaaggtcc agtttcaccc tcgaaggata ccatagcttc
    23461 taggtcgaag tcgtatccat ttgtacggtc agttttgagg tcatagaatt taatggctcc
    23521 aaccccaaca gcatgtgcta cttggtcttt gttttctagt tcaggatttt tagcctcgat
    23581 ttggaccttg gcacggctaa cagcctctgc aacagtaggc tctagcaaga tgacattccc
    23641 tttacgagta gagagcttct tcccttcttt tgtaaccaga ccaaaaggaa cgtgggtaat
    23701 gtcgtcactc caatcgtagc ccatctcttg caagacagct ttgagttgtt taaagtgggc
    23761 agattgctct tgaccaacga cgtagataga tttagcaaat tggtattcat ttttacggta
    23821 gagggctgca gccaagtcac gtgtgatata gagagttgca ccatcagact tcttgatgag
    23881 agctggatgt tcaattccat atttctcaag attcacaact tgggcacctt ctgattcaag
    23941 aagtagtcct ttttcagaaa gaatgtctac aactgcatcc atcttatcat tgtagaaggc
    24001 ttctccgtta tagctgtcaa attcaacctt caattcattg taaaggcggt taaattccac
    24061 taaactttca tcgcggaacc attgccaaag agcgagagct tcctcatctc cattttcaag
    24121 tttacggaac cattcgcgcg cttcttcatc caagctaggg tcattttcag cttcagcgtt
    24181 gatgcggaca tagagtttaa ggagttcatc gattggatga gcttttacag cttcttcgtc
    24241 gccccatttt ttataggcaa caatcaacat cccaaattgt ttaccccagt ctcccaaatg
    24301 gttgaccttg accgtttgat aaccgatttt ttggaaaata tgtgacaagc tatctccgat
    24361 aacagttgaa cgcaggtggc caatagaaaa tggtttagcg atattcggac tagacatgtc
    24421 gataacaaca ttttcttgtt taccaatatt ttggtcagca tagtgttctt tttcagtggt
    24481 aacagcttgc aatacttgag cagaaatggc agatttatca aggaaaaagt taacgtaagg
    24541 tcctgttgcg acaacttttt caaaggcttg gctgttcatt ttttcagcca gttcagccgc
    24601 aatcatttgt ggtgctttac gttcgacttt tgcaagagaa aaagcaggga aagcaatgtc
    24661 tcccatttct gagtttttag gggtttccag taactttaaa atagcctctt ggtccaggct
    24721 atcaatgatg ctagataatt cgctagcaat caattctttt gtattcatta agagctcctt
    24781 tttggacttt tctactattt tatcacaatt ttaaagaaag aagaaaaaat ttttgaaatc
    24841 tcctgttttt ttggtataat atggttataa atatagttat aaatatgcac gcaagaggat
    24901 tttatgagaa aaagagatcg tcatcagtta ataaaaaaaa tgattactga ggagaaatta
    24961 agtacacaaa aagaaattca agatcggttg gaggcgcaca atgtttgtgt gacgcagaca
    25021 accttgtctc gtgatttgcg cgaaatcggc ttgaccaagg tcaagaaaaa tgatatggtg
    25081 tattatgtac tagtaaatga gacagaaaag attgatttgg tggaattttt gtctcatcat
    25141 ttagaaggtg ttgcaagagc agagtttacc ttggtgcttc ataccaaatt gggagaagcc
    25201 tctgttttgg caaatattgt agatgtaaac aaggatgaat ggattttagg aacagttgct
    25261 ggtgccaata ccttattggt tatttgtcga gatcagcacg ttgccaaact catggaagat
    25321 cgtttgctag atttgatgaa agataagtaa ggtcttggga gttgctctca agacttattt
    25381 ttgaaaagga gagacagaaa atggcgatag aaaagctatc acccggcatg caacagtatg
    25441 tggatattaa aaagcaatat ccagatgctt ttttgctctt tcggatgggt gatttttatg
    25501 aattatttta tgaggatgcg gtcaatgctg cgcagattct ggaaatttcc ttaacgagtc
    25561 gcaacaagaa tgccgacaat ccgatcccta tggcgggtgt tccctatcat tctgcccaac
    25621 agtatatcga tgtcttgatt gagcagggtt ataaggtggc tatcgcagag cagatggaag
    25681 atcctaaaca agcagttggg gttgttaaac gagaggttgt tcaggtcatt acgccaggga
    25741 cagtggtcga tagcagtaag ccggacagtc agaataattt tttggtttcc atagaccgcg
    25801 aaggcaatca atttggccta gcttatatgg atttggtgac gggtgacttt tatgtgacag
    25861 gtcttttgga tttcacgctg gtttgtgggg aaatccgtaa cctcaaggct cgagaagtgg
    25921 tgttgggtta tgacttgtct gaggaagaag aacaaatcct cagccgccag atgaatctgg
    25981 tactctctta tgaaaaagaa agctttgaag accttcattt attggatttg cgattggcaa
    26041 cggtggagca aacggtatct agtaagctgc tccagtatgt tcatcggact cagatgaggg
    26101 aattgaacca cctcaaacct gttatccgct acgaaattaa ggatttcttg cagatggatt
    26161 atgcgaccaa ggctagtctg gatttggttg agaatgctcg ctcaggtaag aaacaaggca
    26221 gtcttttctg gcttttggat gaaaccaaaa cggctatggg gatgcgtctc ttgcgttctt
    26281 ggattcatcg ccccttgatt gataaggaac gaatcgtcca acgtcaagaa gtagtgcagg
    26341 tctttctcga ccatttcttt gagcgtagtg acttgacaga cagtctcaag ggtgtttatg
    26401 acattgagcg cttggctagt cgtgtttctt ttggcaaaac caatccaaag gatctcttgc
    26461 agttggcgac taccttgtct agtgtgccac ggattcgtgc gattttagaa gggatggagc
    26521 aacctactct agcctatctc atcgcacaac tggatgcaat ccctgagttg gagagtttga
    26581 ttagcgcagc gattgctcct gaagctcctc atgtgattac agatggggga attatccgaa
    26641 ctggatttga tgagacttta gacaagtatc gttgcgttct cagagaaggg actagctgga
    26701 ttgctgagat tgaggctaag gagcgagaaa actctggtat cagcacgctc aagattgact
    26761 acaataaaaa ggatggctac tattttcatg tgaccaattc gcaactggga aatgtgccag
    26821 cccacttttt ccgcaaggcg acgctgaaaa actcagaacg ctttggaacc gaagaattag
    26881 cccgtatcga gggagatatg cttgaggcgc gtgagaagtc aaccaacctc gaatacgaaa
    26941 tatttatgcg cattcgtgaa gaggtcggca agtacatcca gcgtttacaa gctctagccc
    27001 aaggaattgc gacggttgat gtcttacaga gtctggcggt tgtggctgaa acccagcatt
    27061 tgattcgacc tgagtttggt gacgattcac aaattgatat ccggaaaggg cgccatgctg
    27121 tcgttgaaaa ggttatgggg gctcagacct atattccaaa tacgattcag atggcagaag
    27181 ataccagtat tcaactggtt acagggccaa acatgagtgg gaagtctacc tatatgcgtc
    27241 agttagccat gacggcggtt atggcccagc tgggttccta tgttcctgct gaaagcgccc
    27301 atttaccgat ttttgatgcg atttttaccc gtatcggagc agcagatgac ttggtttcgg
    27361 gtcagtcaac ctttatggtg gagatgatgg aggccaataa tgccatttcg catgcgacca
    27421 agaactctct cattctcttt gatgaattgg gacgtggaac tgcaacttat gacgggatgg
    27481 ctcttgctca gtccatcatc gaatatatcc atgagcacat cggagctaag accctctttg
    27541 cgacccacta ccatgagttg actagtctgg agtctagttt acaacacttg gtcaatgtcc
    27601 acgtggcaac tttggagcag gatgggcagg tcaccttcct tcacaagatt gaaccgggac
    27661 cagctgataa atcctacggt atccatgttg ccaagattgc tggcttgcca gcagaccttt
    27721 tagcaagggc ggataagatt ttgactcagc tagagaatca aggaacagag agtcctcctc
    27781 ccatgagaca aactagtgct gtcactgaac agatttcact ctttgatagg gcagaagagc
    27841 atcctatcct agcagaatta gctaaactgg atgtgtataa tatgacacct atgcaggtta
    27901 tgaatgtctt agtagagtta aaacagaaac tataaaacca agactcacta gttaatctag
    27961 ctgtatcaag gagacttctt tgacaattct ccactttttt gctagaataa catcacacaa
    28021 acagaatgaa aaggagctga cgcattgtcg ctcccttttg tctatttttt aaggagaaag
    28081 tatgctgatt cagaaaataa aaacctacaa gtggcaggcc ttggcttcgc tcctgatgac
    28141 aggcttgatg gttgctagtt cacttctgca accgcgttat ctgcaggaag tattagacgc
    28201 cctccttact gggaaatatg aagctattta tagtatcggg gcttggttga ttggtgtggc
    28261 cgtagtcggt ctagttgctg gtggactcaa tgttgtcctc gcagcctata ttgcccaagg
    28321 agtttcatcc gaccttcggg aggatgcctt ccgtaaaatt caaacctttt cttatgctga
    28381 tattgaacaa tttaatgcgg gaaatctagt cgttcgaatg acaaatgata tcaaccagat
    28441 tcagaacgtt gtcatgatga ccttccaaat tcttttcaga cttcccctct tgttcatcgg
    28501 ttcgtttatc ctagcggttc aaaccttacc ttctctgtgg tgggtgattg ttctcatggt
    28561 agtcttgatt tttggtttga ctgctgtcat gatgggaatg atggggcctc gttttgccaa
    28621 gtttcaaacc cttcttgagc gcatcaatgc cattgccaag gaaaatttac gtggcgttcg
    28681 tgtggtcaag tcctttgtcc aagaaaaaga gcaatttgct aagtttacag aggtctcaga
    28741 cgagcttttt ggtcaaaacc tttacattgg ttatgccttt tcagtagtgg aaccctttat
    28801 gatgttggtt ggttacgggg cggtcttcct ctctatttgg ctggtcgcgg gaatggttca
    28861 gtcggatccg tctgttgttg gttccatcgc ttcttttgtt aattacctaa gccagattat
    28921 ctttaccatt gttatggttg gatttttggg aaattctgtc agccgtgcca tgatttccat
    28981 gcgtcgtatt cgagaaattc ttgacgcaga gccagctatg accttcaagg atatcccaga
    29041 tgaagagttg gttggaagcc ttagctttga aaatgtgacc tttacctatc caatggacaa
    29101 ggaaccgatg ctgaaagatg tgagctttac tattgaacct ggtcaaatgg ttggtgtagt
    29161 tggagcgact ggtgcaggaa agtcaacctt ggctcaattg attccacgtc tctttgatcc
    29221 acagaacggg gccattaaaa tcggtggcaa ggatattcga gaagtgagtg aaggaaccct
    29281 gcgtaaaaca gtttccatcg ttctccaacg tgccattctt tttagtggaa cgattgcaga
    29341 taacttgaga caggggaagg gaaatgctac tctatttgaa atggagcgcg cagccaatat
    29401 tgcccaggct agtgaattca ttcatcgtat ggagaaaacc tttgaaagtc cagttgaaga
    29461 acggggaacc aatttctctg gtggacaaaa acaaaggatg tcgattgcgc gtgggattgt
    29521 cagcaatcca cgtattctga tttttgacga ttcgacctca gccttggatg ccaaatcaga
    29581 gcgcttggtg caagaagctt tgaataagga cttgaagggg acgacaacca ttattattgc
    29641 tcaaaaaatt agctcggttg tccatgcaga caagatcttg gttctaaatc aaggacgatt
    29701 gattggtcaa ggcacgcatg cagacttggt tgccaacaat gccgtttacc gtgaaatcta
    29761 tgaaacacag aaatgaaaga caaactataa gaaaagtcaa tagttttatc taaattattt
    29821 cttatttcaa tttgatgatt tggcgatgat tttagagcac ggcaaaaagc ccttgaaaaa
    29881 gtccattttt tcaaaggtaa tcctgtgttg atttcagaaa ttacatcact ttttgttcgt
    29941 caaatggcag ctctttttta ggatataaaa cagggttcgg ataagttttt ttgcaaggtg
    30001 gatgatggct acattgtaat gttttcctta ttctaactta gtcttaagat aggccttaaa
    30061 agcaggtgaa aagcgagggc atgctttggc agcttgtatg agtgcctacc gcagatgagg
    30121 ggaaccccgt ttgatcattc ttccagctaa atcaatctga tctgactgat aaatagaaga
    30181 atccagtcca gcgaaagctt gtaattgagc aagattatca aaggcatgaa tatttcgaat
    30241 ctcggctaaa atgaccgccc ctaaacgatt cccaatccca gtaaccgtcg tgatgatcga
    30301 gttgaactca gccatcaagt cattgacaca tgtttccgcc ttgtcaatga gcctcttgta
    30361 atgtttgatg ttttcattac acgagataaa acgtttatgc gttatcaaac tcatgaccaa
    30421 ttgaaacaaa aagctgtggt tagatccttt cggaaattgt caagcgattg gaggaaatga
    30481 actaatccac agcggcttat tccaagtata ccacttgggc tttggcagta gctaactgcg
    30541 ctaaatataa tataaggagg agtaaaatga agacagttca atttttttgg cattatttta
    30601 aggtttacaa gttctcattt gtagttgtca tcctgatgat tgttctggcg acttttgccc
    30661 aagccctctt tccagtcttt tctggacaag cggtgacgca gctagccaat ttagttcaag
    30721 cttatcaaaa tggcaatcca gaacttgtat ggcaaagcct atcaggaatc atggtcaatc
    30781 ttggcctgct ggttttggtt ctatttatct ctagtgtaat atacatgtgt ctcatgacgc
    30841 gcgtgattgc agaatcgacc aacgagatgc gcaaaggcct ctttggtaag cttgctcagt
    30901 tgacggtttc tttctttgac cgtcgacaag atggcgatat cctgtctcat tttaccagtg
    30961 atttggataa tatcctccaa gcctttaacg aaagcttgat tcaggtcatg agcaatattg
    31021 ttttatacat tggtctgatt cttgtcatgt tttcgagaaa tgtgacgctg gctctcatca
    31081 ccattgccag caccccattg gctttcctta tgctgatttt catcgtgaaa atggcacgca
    31141 aatacaccaa cctccagcag aaagaggtag ggaagctcaa cgcctatatg gatgagagca
    31201 tctcaggcca aaaagccgtg attgtgcaag gaattcaaga ggatatgatg gcaggatttc
    31261 ttgaacaaaa tgagcgcgtg cgcaaggcaa cctttaaagg aagaatgttc tcaggaattc
    31321 ttttccctgt catgaatggg atgagcctga ttaatacagc catcgtcatc tttgctggtt
    31381 cggctgtact tttgaatgat aagtctattg aaacaagtac agccctaggt ttgattgtta
    31441 tgtttgcaca attttcacag cagtactacc agcctattat ccaagttgca gcgagttggg
    31501 gaagtcttca gttggccttt actggagctg aacgaattca ggaaatgttt gatgcagagg
    31561 aggaaatccg acctgaaaag gctccaacct tcactaagtt gcaagaaagt gttgaaatca
    31621 gtcatatcga tttttcatac ttgcctgata aacctatttt gaaagatgtc agcatttctg
    31681 cccctaaagg ccagatgaca gcagttgttg ggccgacagg ttcaggaaaa acgactatta
    31741 tgaacctcat caatcgcttt tatgatgttg atgctggtgg tatttatttt gatggtaaag
    31801 acattcgtgg ctatgactta gatagtctta gaagcaaggt gggaattgta ttgcaagatt
    31861 cggtcttgtt tagcggaacg attcgagaca atatccgatt tggtgtgcca gatgctagtc
    31921 aggaaatggt tgaggtagca gcaaaagcaa cccacattca cgactatatc gaaagtttgc
    31981 ctgataagta cgatactctt attgatgatg accagagcat cttttcaaca gggcagaagc
    32041 aattgatttc aatcgctcga accctgatga cagatccaga agttctcatt ctcgatgaag
    32101 caacttcaaa cgtagatacg gtgacagaaa gcaagattca gcatgccatg gaggtggttg
    32161 tagcaggtag aactagtttc gtcattgccc accgcttgaa aaccattctc aatgcagatc
    32221 agattattgt ccttaaagat ggagaagtca ttgaacgtgg taaccaccat gaacttttga
    32281 agctaggtgg cttttattca gaactctatc acaatcaatt tgttttcgaa taagaaagaa
    32341 gttgtcctat gtgggcagct ttttcttgtc cataaaaaat ctttatcaca gccttaaaaa
    32401 aaacatatta gacgaaagtc attttgagtg atatgatagg actatcgtta gcattcgaaa
    32461 ggagaggcat catggctaga acggttgtag gagttgctgc aaatctatgt cccgtagacg
    32521 cagaaggcaa aatcattcat tcatctgtat cttgtagatt cgcagagatc attcgtcaag
    32581 tcggtggtct ccctttagtc attcctgttg gtgatgagtc agttgtacgt gattatgtgg
    32641 aaatgattga caaactcatt ttgacaggag gccaaaatgt tcatcctcag ttttatggag
    32701 agaaaaagac cgtcgagagc gatgattaca atctggtccg tgacgaattt gaattggcac
    32761 tcttgaagga agcgcttcgt cagaataaac caattatggc aatctgtcgc ggtgtccaac
    32821 ttgtcaatgt tgcctttggt ggaaccctca atcaagaaat cgaaggtcac tggcaaggac
    32881 tacctttcgg gacatctcac tctattgaga cagtagaagg aagcgtggtg gctaagctat
    32941 ttgggaaaga aagtcaggtc aactcagtcc atcgtcaaag cattaaagat ttggcaccta
    33001 atttccgtgt aactgctatt gattcaagag accaaactat tgaagcgatt gagtctatcg
    33061 acgagcaccg cattatcggt ttacagtggc atccagagtt tctggttaat gaagaagatg
    33121 gcaatttaga attatttgag tatttattga atgaactgta acgattggaa catctggtcg
    33181 ttctttcttt tattttttca aaatttttag aatgtggcat tttacgcaaa cgtttgaatt
    33241 ctgataaaaa ttggagaaat tcgacaaaaa aacttgaaaa aaacgaaggt aagcgttatg
    33301 atagaaaaga agaaatattg gaggaagaac atgtcacata ttaaatttga ttattcaaaa
    33361 gttttagaca aatttgttgc accacatgaa gtggaataca tgcaatcaca agtaacagca
    33421 gcagatgaat tgatccgtaa aggaactggt gctggtagcg acttcttggg atggttggac
    33481 cttcctgaaa aatacgatcg cgaagaattt gaccgcatct tgaaagctgc tgagcaaatc
    33541 aagtcagaca gcgatgtttt ggttgtgatc ggtattggtg gatcttacct tggtgcaaaa
    33601 gcagcaatcg acttcttgaa tcaccatttt gctaacttgc aaacaaaaga agaacgcaaa
    33661 gctccacaaa tcctttacgc aggaaactca atctcatcta cttaccttgc tgacttggta
    33721 gagtatgttg cagacaaaga cttctcagta aacgtaattt ctaaatcagg tacaacaact
    33781 gaaccagcga ttgctttccg tgtctttaaa gaactcttgg ttaagaaata cggtcaagaa
    33841 gaagctaaca aacgtatcta tgcaacaact gaccgccaaa agggtgctgt taaggttgaa
    33901 gcagacgcta acggttgggg aacatttgtt gttccagatg atatcggtgg acgcttctca
    33961 gtattgacag ccgttggttt gcttccaatc gcagcatcag gagctgacat caaagctctt
    34021 atggaaggtg cgaatgcagc tcgcaaagac tacacttcag acaaaatctc tgaaaacgaa
    34081 gcttaccaat acgcagctgt tcgtaacatc ctttatcgta aaggctatgc aactgagatc
    34141 ttggtaaact atgagccatc acttcaatac ttctcagaat ggtggaaaca attggctggt
    34201 gaatcagaag gaaaagacca aaaaggtatc tacccaactt cagccaactt ctcaactgac
    34261 ttgcactcac ttggtcaatt tatccaagaa ggaactcgta tcatgtttga aacagttgtc
    34321 cgtgttgaca aacctcgtaa aaacgtgctt attcctactt tggaagaaga ccttgacgga
    34381 cttggttacc ttcaaggaaa agacgttgac tttgtaaaca aaaaagcaac tgacggtgtt
    34441 cttcttgccc acacagatgg tgatgtacca aacatgtatg tgactcttcc agagcaagac
    34501 gctttcactc ttggttacac tatctacttc ttcgaattgg caattgccct ttcaggttac
    34561 ttgaatgcta tcaacccatt tgaccaacca ggtgttgaag cttataaacg taacatgttt
    34621 gcccttcttg gaaaaccagg atttgaagaa ttgagcaaag aacttaacgc acgtctataa
    34681 tagaagaaaa gagtggtttg cccactcttt ttactctctt tatccataga aattggactc
    34741 agccaagact tgtgatataa tatagaaagc aaaaaggcag acgcctagat aataggagaa
    34801 actatgtcaa aagatatccg cgtacgttac gcaccaagtc caacaggact actacacatc
    34861 ggaaatgctc gtacagcatt gtttaattac ttgtatgcgc gccatcatgg tggaacattt
    34921 ctcatccgta tcgaagatac tgaccgtaaa cgccatgtcg aggatggtga acgttcacaa
    34981 cttgaaaacc ttcgctggtt aggcatggat tgggatgaaa gtccagaatc acatgagaat
    35041 tatcgccagt ctgagcgttt ggacttgtat caaaaataca tcgaccaact attagctgaa
    35101 ggaaaagcct acaaatctta cgttacagaa gaagagttgg tagctgaacg tgaacgtcaa
    35161 gaagtagctg gcgaaacacc acgctacatc aatgaatacc ttggtatgag tgaagaagaa
    35221 aaagcagctt acatcgcaga acgtgaagca gcagggatca tcccaactgt tcgtttggct
    35281 gtcaatgagt caggtatcta caagtggcat gatatggtca aaggcgatat cgaatttgaa
    35341 ggtggcaata tcggtggtga ctgggttatc caaaagaaag acggttaccc aacttacaac
    35401 tttgccgttg ttatcgatga ccacgatatg caaatctctc atgttatccg tggagatgac
    35461 catattgcta atacaccaaa acagcttatg gtctatgaag ctcttggttg ggaagctcca
    35521 gagttcggtc acatgacctt gattatcaac tctgagactg gtaagaagtt atctaaacgt
    35581 gatactaata cacttcaatt tatcgaagat taccgaaaga aaggttacct tccagaagca
    35641 gtctttaatt ttattgctct tcttggttgg aacccaggtg gtgaagatga gattttctct
    35701 cgtgaagaac tcattaaact ttttgatgaa aaccgcctca gcaagtcacc agcagccttt
    35761 gatcagaaaa aactagactg gatgagcaat gattatatca agaatgcaga ccttgaaacc
    35821 atctttgaaa tggcaaaacc attcttagag gaagcaggcc gtttgactga caaggctgaa
    35881 aaattagttg agctctataa accacaaatg aaatcagtag atgagattat cccattgaca
    35941 gatcttttct tctcagattt cccagaattg acagaagcag agcgcgaagt catgacgggt
    36001 gaaacagttc caacagttct tgaagcattc aaagcaaaac ttgaagcgat gacagatgat
    36061 aaatttgtga cagaaaatat cttcccacaa attaaagcag ttcaaaaaga aacaggtatt
    36121 aaagggaaaa atcttttcat gcctattcgt atcgcagttt caggcgaaat gcatgggcca
    36181 gaattaccag atacaatttt cttgcttgga cgtgaaaaat caattcagca tatcgaaaac
    36241 atgctaaaag aaatctctaa ataaagagga tacaataatg gacatctggg aaaagatgta
    36301 cgaagaagca cagaaactat acaatccaca tgaagtatca gactttgttt atgccaatca
    36361 tgttgtagct gcagtagaag cagaagatgg acaaatattt acaggattct gtatggaggg
    36421 aacctgtggt gttttccatc tctgcgcaga acgggcggcc ctctttaata cgtaccaatt
    36481 ttcaggacaa actaaggtta agaaagtatt agcctttcga gacaaaccac cttatggtgg
    36541 aagttcagcc atgccttgcg gtgcttgtag agaattcctt ttagagctta atgctgaaaa
    36601 taaagatgca gaattcatga tggactataa tataagaaaa acagttaaag tcgcagaact
    36661 aatcccttat tggtgaggag aagaacgtgc ttctaagttt aatgagcgat agaagagtca
    36721 gtataattct ggcttttttt actata
//
LOCUS       DAVLUM010000011        36014 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLUM010000011 DAVLUM010000000
VERSION     DAVLUM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.011"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            146..280
                     /gene="rpmH"
                     /locus_tag="VYN42_000442"
     CDS             146..280
                     /gene="rpmH"
                     /locus_tag="VYN42_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1461570.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            564..1457
                     /locus_tag="VYN42_000443"
     CDS             564..1457
                     /locus_tag="VYN42_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1461571.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            1762..2535
                     /locus_tag="VYN42_000444"
     CDS             1762..2535
                     /locus_tag="VYN42_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1461572.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            2535..3095
                     /gene="rnmV"
                     /locus_tag="VYN42_000445"
     CDS             2535..3095
                     /gene="rnmV"
                     /locus_tag="VYN42_000445"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1461573.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            3167..4077
                     /locus_tag="VYN42_000446"
                     /pseudo
     CDS             3167..4077
                     /locus_tag="VYN42_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4397..4693
                     /locus_tag="VYN42_000447"
     CDS             4397..4693
                     /locus_tag="VYN42_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1461574.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            4770..6800
                     /locus_tag="VYN42_000448"
     CDS             4770..6800
                     /locus_tag="VYN42_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1461575.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIASGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRIMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            6802..7443
                     /locus_tag="VYN42_000449"
     CDS             6802..7443
                     /locus_tag="VYN42_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461576.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            7436..7594
                     /locus_tag="VYN42_000450"
     CDS             7436..7594
                     /locus_tag="VYN42_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461577.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEG"
     gene            7875..8747
                     /gene="rsmA"
                     /locus_tag="VYN42_000451"
     CDS             7875..8747
                     /gene="rsmA"
                     /locus_tag="VYN42_000451"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1461578.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLSIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            8749..9627
                     /gene="rsgA"
                     /locus_tag="VYN42_000452"
     CDS             8749..9627
                     /gene="rsgA"
                     /locus_tag="VYN42_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1461579.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            9638..10294
                     /locus_tag="VYN42_000453"
     CDS             9638..10294
                     /locus_tag="VYN42_000453"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1461580.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            10257..10919
                     /locus_tag="VYN42_000454"
     CDS             10257..10919
                     /locus_tag="VYN42_000454"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1461581.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            10921..12177
                     /locus_tag="VYN42_000455"
     CDS             10921..12177
                     /locus_tag="VYN42_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1461582.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            12167..13108
                     /locus_tag="VYN42_000456"
     CDS             12167..13108
                     /locus_tag="VYN42_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1461583.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            13375..14202
                     /gene="purR"
                     /locus_tag="VYN42_000457"
     CDS             13375..14202
                     /gene="purR"
                     /locus_tag="VYN42_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1461584.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            14269..15519
                     /locus_tag="VYN42_000458"
     CDS             14269..15519
                     /locus_tag="VYN42_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1461585.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            15645..16439
                     /gene="pflA"
                     /locus_tag="VYN42_000459"
     CDS             15645..16439
                     /gene="pflA"
                     /locus_tag="VYN42_000459"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1461586.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(16514..17440)
                     /gene="yidC"
                     /locus_tag="VYN42_000460"
     CDS             complement(16514..17440)
                     /gene="yidC"
                     /locus_tag="VYN42_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1461587.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(17518..17796)
                     /locus_tag="VYN42_000461"
     CDS             complement(17518..17796)
                     /locus_tag="VYN42_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1461588.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17830..18570
                     /locus_tag="VYN42_000462"
     CDS             17830..18570
                     /locus_tag="VYN42_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1461589.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTAEAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVATGILIFHLS"
     gene            18626..19309
                     /locus_tag="VYN42_000463"
     CDS             18626..19309
                     /locus_tag="VYN42_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1461590.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            19420..20412
                     /locus_tag="VYN42_000464"
     CDS             19420..20412
                     /locus_tag="VYN42_000464"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1461591.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            20477..21016
                     /gene="rsmD"
                     /locus_tag="VYN42_000465"
     CDS             20477..21016
                     /gene="rsmD"
                     /locus_tag="VYN42_000465"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1461592.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            21006..21494
                     /gene="coaD"
                     /locus_tag="VYN42_000466"
     CDS             21006..21494
                     /gene="coaD"
                     /locus_tag="VYN42_000466"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1461593.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            21478..22515
                     /locus_tag="VYN42_000467"
     CDS             21478..22515
                     /locus_tag="VYN42_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1461594.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKEILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            22573..22803
                     /locus_tag="VYN42_000468"
     CDS             22573..22803
                     /locus_tag="VYN42_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1461595.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            22827..24110
                     /gene="murA"
                     /locus_tag="VYN42_000469"
     CDS             22827..24110
                     /gene="murA"
                     /locus_tag="VYN42_000469"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1461596.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            24103..24291
                     /locus_tag="VYN42_000470"
     CDS             24103..24291
                     /locus_tag="VYN42_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1461597.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            24330..25154
                     /gene="endA"
                     /locus_tag="VYN42_000471"
     CDS             24330..25154
                     /gene="endA"
                     /locus_tag="VYN42_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1461598.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            25445..26776
                     /locus_tag="VYN42_000472"
     CDS             25445..26776
                     /locus_tag="VYN42_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1461599.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(26974..27044)
                     /locus_tag="VYN42_000473"
     tRNA            complement(26974..27044)
                     /locus_tag="VYN42_000473"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27010..27012),aa:Cys,seq:gca)
     gene            27460..31071
                     /gene="rpoB"
                     /locus_tag="VYN42_000474"
     CDS             27460..31071
                     /gene="rpoB"
                     /locus_tag="VYN42_000474"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1461600.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            31104..34781
                     /gene="rpoC"
                     /locus_tag="VYN42_000475"
     CDS             31104..34781
                     /gene="rpoC"
                     /locus_tag="VYN42_000475"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1461601.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            34892..35305
                     /gene="ndk"
                     /locus_tag="VYN42_000476"
     CDS             34892..35305
                     /gene="ndk"
                     /locus_tag="VYN42_000476"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1461602.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
BASE COUNT        10596 a         6908 c         8391 g        10119 t
ORIGIN      
        1 gggcttgcat tcgaaaaagc tggaaacatt tgcctagagc tattgacaaa agtgaaagaa
       61 tcagatagaa tagtaaagta tgtttagtaa ctgatcactt tatagccggc taaacgaata
      121 caaaatctat gaggaggtat tcatcgtgaa acgtacttat caaccaagta aacttcgtcg
      181 tgcgcgcaaa cacggattcc gtaaccgtat gtcaactaaa aatggtcgtc gcgtattggc
      241 agctcgtcgt cgtaaaggac gcaaagtttt ggctgcataa tccaaacgaa ttctatcaaa
      301 aatcagtagg aactcgagtc tactgatttt tatttttgta aaaaagttca gtagatgcaa
      361 atggattcgg aagcgatgtt acagtagatt gaaactagaa tagtacacct ctgtttctaa
      421 aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttatt attttatttt
      481 actataaagt tgaagtaggt ggagatggta cagcaacaat cgtctttaaa gatggttcag
      541 ctattacaat tccaggaaat caattggtag cacaagatcc aaaagcacaa gatagcacta
      601 aactgactgc tgaaaaatca actgttaaag cacctgctca aagagtagat gtaaaagata
      661 taactcattt aacagatgaa gaaaaagtta aggttgctat tttacaagca aatggttcag
      721 cattagacgg agcgacaatc aatgtagctg gagatggtac agcaacaatc acattcccag
      781 atggttcagt agtgacgatt ctaggaaaag atacagttca acaatctgcg aaaggtgaat
      841 ctgtaactca agaagctaca ccagagtata agctagaaaa tacaccaggt ggagataagg
      901 gaggcaatac tggaagctca gatgctaatg cgaatgaagg cggtggtagc caggcgggtg
      961 gatcagctca cacaggttca caaaactcag ctcaatcaca agcttctaag caattagcta
     1021 ctgaaaaaga atcagctaaa aatgccattg aaaaagcagc caaggacaag caggatgaaa
     1081 tcaaaggcgc accgctttct gataaagaaa aagcagaact tttagcaaga gtggaagcag
     1141 aaaaacaagc agctctcaaa gagattgaaa atgcgaaaac tatggaagat gtgaaggaag
     1201 cagaaacgat tggagtgcaa gccattgcca tggttacagt tcctaagaga ccagtggctc
     1261 ctaatgctgc tcctaagaca acaagtgcac cgcaagcaac tgcaggaaca atgcaagatg
     1321 ttacctacca gtcacctgct ggcaaacaat tacctaacac aggttcagca tcaagtgcag
     1381 cacttgctag tcttggtcta gtggtggcaa caagtggttt tgctttgcta ggaagaaaga
     1441 ctagacgtag aaaatagaac agctagaaaa ttctattctc tacttaaagt tagattataa
     1501 gggggatttt gagaagtcat caatcctagt gatgggtgag aaaagtgaga acccaagata
     1561 atcacatact ttagctgaat aggaatattc tatcaatgta gccaatctct tctgtctcta
     1621 actgtggaat aggagatggg caatatcgga tagaaaagat agcagaatag ctctctattg
     1681 aagagaggag gggaaaccga aaaattaggt gcccctcctc ttttttggta taatagaaga
     1741 tagaaaacga ggttagaaga gatgattttt gatacacata cacacttgaa tgtagaagaa
     1801 tttgcaggtc gtgaggcaga agaaattgcc ttggctgctg agatgggtgt gacacagatg
     1861 aatattgttg gttttgataa accgacgatt gagcatgcct tggagttggt agatgagtat
     1921 gagcagctct atgcgactat tggttggcat cctacagaag ctggtactta tacagaggaa
     1981 gttgaggctt acttgttgga taagttaaaa cattccaagg ttgtggcttt aggtgaaatt
     2041 ggcttagatt accattggat gacagcgccc aaagaggtgc aggagcaggt ttttcgccgt
     2101 cagattcagc tatctaagga cttggatttg ccttttgttg tccatacccg tgatgcgctg
     2161 gaagatacct atgagattat caagagtgag ggcgttggtc ctcgtggtgg tatcatgcat
     2221 tcattttcag ggacgcttga gtgggcagag aagtttgtgg atcttggtat gaccatttcc
     2281 ttctcaggag tggtgacttt taagaaggca actgacctcc aagaagcagc taaagagtta
     2341 cctttggaca agatgttggt ggaaacagat gcgccttact tagcacctgt acccaagcgt
     2401 ggtcgtgaaa ataaaacagc ctatactcgc tatgtggtcg actttatcgc tgacttgcgt
     2461 ggtatgacga cagaagagct ggcggtagca acgactgcaa atgcagaacg aatttttgga
     2521 ctggacagca agtaatgaaa gagaaaattt ctcaagttat cgtggttgaa gggcgtgatg
     2581 atacggtcaa tctcaaacgt tatttcgatg tggagaccta tgagactcga ggttctgcca
     2641 tcaatgctca ggatatagag cggattcagc gcctgcacca acgtcatgga gtcattgtct
     2701 ttacagaccc agattttaat ggggaacgga ttcggcgcat gatcatgatg gtcattccaa
     2761 cagttcagca tgcatttctc aagcgagatg aagctgttcc caagtccaag accaaggggc
     2821 gttctctggg aattgagcat gccagctatg aagacctgaa aacggctcta gctcaggtga
     2881 cagaacaatt tgaacatgag agtcagtttg acattagtcg tagcgatttg attcgccttg
     2941 gttttctagc aggggcagac agccgtaagc gtagagaata tctcggagag actctccgaa
     3001 tcggctattc caacggcaag caactcctca aacgcctaga gttgtttggg gttactttgg
     3061 cagaagtgga agaagctatg aaatcttatg agtaggaaag atgtagccgt tacaattttt
     3121 taagtttcac agtatttttc gaagcaggta gaagaggagg cgtctgatgt taattggtca
     3181 aaaaattaaa gagattcgga tagaaaaagg aattagtcgt ccagattttt gtggagatga
     3241 gcaagaactg acagttcgtc aactgtcgcg aattgaaagt ggagcttcgc aaccgagttt
     3301 gcccaagtta gcctatattg ctcgccggct aggagttcca gtttatagcc ttatgccgga
     3361 tttttcagct cttcctcctg cttatttaga attgaaatac cagattttac gtgaaccaat
     3421 ctatggtaaa gaagaggagt acgataagaa ggaagcgtgt ttggaagaga tttataaaac
     3481 atttataaaa catactttga taatcttcct aaagaagaac aattagcatg tgaagtattg
     3541 caggcgtgtt tggatacttc tagaactaga aggcctgaat atgcagagtt aatacttgag
     3601 gaacatatgc ctcagattat agaaaaagaa gcttattcaa taaatgatat gttgttgatt
     3661 cgtttgtttt tttatcaaat gctcattaga aaagatcttg ccaaatttat aaatcaaatc
     3721 gaaaagctaa tgctctttct tttggaacag aagaaggtaa ctcaaataga gaattacttt
     3781 ataattagag atactcttat ttcaggaatg tgttgtcttg aaaaggtagg agtaactgat
     3841 tgttttaatg attatctatc gtgtttacaa gaaattatgg ataaaactca agattatcaa
     3901 aagaaacctc ttgtatttat gtttttgtgg aagcaagcat taagagtaga aagagatttt
     3961 agtttagctg aatcatttta tcagtcttct aaaacatttg cgcagctaat tggagatgaa
     4021 tttctagtaa agaaattgac agaggaatgg caagaggatg tcaaaaaata tttataaaca
     4081 tagtgaatca gtgacaaaaa tgtccttgtc ctcgtatcaa aacagttcta aagttcgtct
     4141 ttagaactgt ttttttagat ataagctaaa aataatatga aatagttaga ttttaaggac
     4201 attgatgtcc ttgatagtgt gataaagatg gagtataatg actataaaag ttcatttcag
     4261 ggtgctattt tgacaattta gagaaaaaca aataatttta gaatatcatt tggtaatata
     4321 atagtatcaa cgttgataat ggaaagagga gcaagtaact caacaatctt gtaatcaaaa
     4381 atagaggagt atcaatatga aacaaacagt taaaaagtta gctcttgtag cgagcattgc
     4441 agcaacatta ggtggaggtg tatcagttgc ctctgcagcc gttcaatacc cagaaggtgg
     4501 tgtttggact tatggttcag gtaacggtgg tgcttactca aactactatc acccttcaaa
     4561 ataccatagt tcaacagttg ttagcagaaa aactggttca tctgacaagg gatatgctgg
     4621 tgctggaggg acttctcgtg catggattcg tacttcttgg ggagagaaag ttgcattcta
     4681 ctataatgtt tagaatggta tagccctatt gtttagcttt acttggtcac cttctcacta
     4741 agtgaccaag taactttttg gaggaaatga tgaaacgttt atttattttg atttcaatgg
     4801 tattagtatc gctttatatg gtgataactt ccgttgacca tcgagaagag attttatttg
     4861 gtaactatcc ttctgttgat gtgacaggaa tgatgataaa tcaaccagta gctagtcgcg
     4921 aagaggtgac agaggctttg agtcacttgg cggtagagca caatagtctc attgctcgtc
     4981 gaatcgttga gccaaatgaa gctggagaaa cacgctttac ctatgccact tatggtgagg
     5041 gaaagcttcc agaaggtctg accatttcct ccaaggagag tgcagaaacg agtgatttat
     5101 tagggtctta cttgattgca tcaggaagtt tggatggagt gagcttacag accaccttga
     5161 aagagcttgg ttatcaaggc tttgtttcga atggagaaga tccattttcg atagtcttac
     5221 tattgacggc cacccctatg gtgctactga gtttagctat ttttctgctg acctttatga
     5281 gtctgaccct gatttatcgg atcaaatccc ttcgtcaggc agggattcgc ttaatagctg
     5341 gtgagagctt gtttggagtt gctctcagac cagtgttaga agatgtgaga cagcttatct
     5401 gctcagtgct ggtatccagt cttttgggat tggggattct ctggtatcaa ggtgccttgt
     5461 ttatggcaac ggtgcaactg gtcatcattg ctcttctact ttatggattg accctggcag
     5521 ggatttctac cttactaagt gtcgtctatc tacttggttt acaggaaaat agtctggtgg
     5581 atctattgaa agggaaactc cctctcaaac gtataatgac attgatgatg gtggggcaac
     5641 tcttagctgt attggtggtc ggatcgagtg cgacagctct cctaccccac taccgtgaaa
     5701 tgcaggaaat ggagagagct agcaataaat ggagccagtc ctcagaccgt taccgtctat
     5761 cctttggttg gtctagtgca tttgccgatg aagaaggaac gcgtaaggat aatcgtgagt
     5821 ggcagacatt tactgaagaa cggttagcca atacagactc tttttatatt atgagcaatg
     5881 ttgacaattt ctcagatgga gcagaagtgg acctagatgg caatcgtctc agtgactaca
     5941 caccgtcagg gaatgttatc tatgtctcac cacgctatct gatagaagaa aagattaccg
     6001 tttcttcaga gtttatggac aagatgcaaa acttgtctga gggagagttt gggctgatct
     6061 tgcctgagag cttgcgagag cagtctgtct actaccaagg attgtttaca gattacctgc
     6121 aaaacttttc atctgaaagt gtagaagtga cgagtcagaa acactacctc ccacaggtaa
     6181 ggctagcttt tacagaaaca ggacaggaac gtttcctcta taatgatggg tacaagacaa
     6241 cacgccagta cctaaaagat ccgattattg tagttctaac gccgcaagcg actggaacaa
     6301 gacctgttgc agggatgttg tggggaacta cggctaatag tgccttgaaa ctagatcgat
     6361 atggagacag catcacagct ctaaaagagc aaggtctgta tcacaaggtt tcttacttgg
     6421 taaaaagcca gctatttttt gccaaggtac taaatgacaa acgggtggag ttttactctc
     6481 tccttattgg gacgattttg accctgtcta cggctatctt gttatttgat tccatgaatc
     6541 ttctctattt tgagcagttc agacgggagc ttatgattaa acgtcttgct ggtatgacaa
     6601 tctatgagct tcatggcaag tatttactgg cgcaaggagg agttctcttg cttggcctag
     6661 tcctatctag tattttgaca agagatggtt tgattagtgc tctagttgta gctttgttta
     6721 cgcttaacgc cctcttgatt ttagtaaggc aggacaaaaa agaagaagct ggtagcatgg
     6781 cagtattgaa aggaaaataa gatgattgat attcaaggat tggaaaagaa atttaatgac
     6841 cgcgcgattt tctctggttt gaatctcaag ctggagaagg gcaaggttta tgccttaatc
     6901 ggaaagagtg gaagcggaaa gacgacgctg ctgaatatct tgggaaagct agaaaagata
     6961 gatggaggaa gggttctcta tcaggggaaa gatttaaaaa ccattcccac tcgtgagtat
     7021 tttcgagatc agatgggcta tctctttcaa aattttggcc tcttagaaaa ccaatcaatc
     7081 aaagaaaatt tggatttggg ttttgttggt cagaaaatct caaaagtaga acgtttggaa
     7141 aggcaagtgg gggctttaga aaaagttaat ctagggtatt tggatttaga acaaaaaatc
     7201 tatactttat ctgggggaga ggcccaacga gttgcccttg ctaagactat tttgaaaaat
     7261 ccacccttga ttttggcaga tgaaccaaca gcagctcttg atcctgaaaa ttcagaggag
     7321 gttatgaatc tcttggtgga tttgaaagat gaaaatcgaa ttatcatcat tgcgacccat
     7381 aatcccctag tctggaataa ggctgatgaa atcattgata tgaggaaact tgctcatgtg
     7441 tgaaaaaatc cgtattcgca gggtatctga ttatcctagt gccagaggtg gtttagaaga
     7501 tatcctcatc atggaaaata tgaccaatca tctccttttg gttcaaatcc gagtgcatgg
     7561 ctatttgctt gattttgcta gtattgaagg gtaaaggcaa aagcattatc gtttgaaaaa
     7621 tttacctcaa acggttgaac tgacagtgga tgatgtggaa gaggatgtgg atttaaccct
     7681 acccgaaaat cgaagttatc aagaagctga tttttttgaa cgcatgtttc gagagaactg
     7741 ctaaggccac ttttaaagat ttccaagact atctttcttc atgaggaaag atagtttttt
     7801 ggtatgattt tcattcccaa aatacaaggg gaatgtgtta caatagtagt aacagataat
     7861 agaaaagaga atagatgaga attgcagatt atagcgtgac caaggcagtg ctggagcgtc
     7921 acggttttac ctttaaaaag tcctttgggc aaaatttttt gacggatacc aatatccttc
     7981 aaaaaattgt ggatacggct gaaattgatg atcaggtcaa tgtcatcgaa atcgggccag
     8041 gtattggtgc cttgacagaa tttttggctg agcgtgcagc ccaagtcatg gcttttgaga
     8101 ttgaccaccg tttggtgcca attttggcag ataccctgcg tgattttgat aatgtgactg
     8161 tagttaacga agatattctc aaggttgatt tggcgcaaca tatccaaaat tttaaaaatc
     8221 ctaacctgtc aatcaaggta gtggctaatt tgccttacta catcacgacg cctattctca
     8281 tgcacttgat tgagagtggg attcctttta gtgagtttgt ggtcatgatg cagaaagaag
     8341 tagcggaccg catttcagcc cagcctaaca ccaaggctta cggtagcttg tctatcgccg
     8401 tgcagtatta catgacagcc aaggttgcct ttatcgtgcc tcgtacggtc tttgtgccag
     8461 cgccaaatgt ggattcagcc atcttgaaaa tggtgcgccg tccagagcca gctgtagcag
     8521 tggaagatga gaacttcttc tttaaggttt ccaaggctag ttttacccat cgccgtaaga
     8581 ccttgtggaa taacttgaca ggttactttg gtaagactga agaggtcaag gacaagctga
     8641 ccaaggcttt ggaccaggca ggcttgtcac caagtgtgcg tggggaagct ctcagcttgg
     8701 cagaatttgc cggtctagca gacgcactta aagggcaagg actctaagat gcagggacaa
     8761 atcattaaag ccttggcagg tttctactat gtggagagtg atggccaggt ttatcaaaca
     8821 cgcgcgcgtg ggaatttccg taaaaaaggc catacccctt atgttgggga ctgggtggat
     8881 ttctctgccg aggaaaattc agaaggctat atcctaaaaa ttcacgaacg gaaaaacagt
     8941 ctggttcgtc cgcctattgt caatatcgat caagctgtag taatcatgtc cgtcaaggaa
     9001 cctgatttta acagcaattt gctggatcgt ttcttggttc ttttggagca caagggcatc
     9061 catcccattg tctatatttc caaaatggat ttgttggaag ataggggaga actggatttt
     9121 taccggcaga cctatggtga catcggctat gactttgtga ccagtaaaga ggaactcctg
     9181 tctttgttaa caggcaaggt tacggtcttt atggggcaga caggtgttgg gaagtcaact
     9241 cttctcaata aactcgtacc agacctcaat cttgaaacgg gagaaatttc agacagtcta
     9301 ggtcgcggtc gccataccac tcgagctgtt agtttttaca atctcaacgg gggtaaaatc
     9361 gcagacacac caggcttttc atctctggac tatgaagtat caagggctga agacctcaat
     9421 caggctttcc cagagattgc tactgtcagc cgagattgta agtttcgtac ttgtacccat
     9481 acccatgagc cgtcttgtgc cgtcaagcca gctgtagaag aggggaccat tgccaccttc
     9541 cgttttgaca actacctgca attcctcagc gaaattgaaa atcgtagaga aacctataaa
     9601 aaagtcagca aaaaaattcc aaaataagga gaaacctatg tctcaataca agattgctcc
     9661 gtcaattctg gcagcagatt atgccaactt tgaacgtgaa atcaaacgtc tagaagcaac
     9721 tggggcagaa tatgcccata tcgatatcat ggacagtcat tttgtaccgc aaatcagttt
     9781 tggtgcaggt gtggtcgaga gccttcgtcc tcatagtaag atggttttcg attgccactt
     9841 gatggtgtca aaccctgagc atcatctgga agattttgcg cgtgcaggtg cagacatcat
     9901 cagtatccat gtagaagcaa cacctcatat tcatggcgcc ctccaaaaaa ttcgttcact
     9961 cggagttaag ccttcagtcg ttatcaatcc tggcacacca gttgaagcca tcaagcacgt
    10021 ccttcatcta gttgaccaag ttttagtcat gacggttaat ccaggttttg gtgggcaagc
    10081 ctttctgcca gaaaccatgg ataaggttcg tgagttggtt gctcttcgtg aggaaaaagg
    10141 tttgaacttt gaaatcgaag tggatggtgg gattgatgac caaactattg ctcaagccaa
    10201 agaagctggt gcgactgttt ttgtagcagg ttcctatgtc tttaagggag aagtcaatga
    10261 gcgagtacaa actctcagaa aacaactgga ctagggttgc agtttttgca ggcggaaacc
    10321 gcggtcatta tcggacagat tttgatgctt ttgttggggt ggatcgaggc tcgctctggg
    10381 tcttggaaga agacttacct cttgctctag cagtcggaga ttttgattct gtgacggaag
    10441 aagagcgaca ggtgattcaa aaacgtgccc agtattttgt ccaagcccga ccagaaaagg
    10501 atgatacaga tctggaattg gctctcttaa ccatctttga acaaaatcct caggctcagg
    10561 tcactatttt cggtgccttg ggtggccgta ttgaccatat gttggccaat gtctttctac
    10621 ctagcaatcc taagttggca ccctatatgc gtcaaataga aattgaggat gggcaaaatt
    10681 tgattgccta ttgttcagaa gggaccagtc agctagaacc tcgttcagac tacgactatc
    10741 tagcctttat gccagttcgg gatagccagc tgactattct tggagctaag tatgagttga
    10801 cagaggagaa ttttttcttt aaaaaagtgt acgcttctaa cgaatatata gatagggaag
    10861 tgtcggtaac ttgcccagat ggttatgtgg tcgtactgca tagcaaggac aggaggtagg
    10921 atggaaagtt tacttattct attattaatt gccaacctag ctggtctctt tctgatttgg
    10981 caaaggcagg ataggcagga gaaacactta agtaagagct tggaggatca ggcagatcat
    11041 ttgtcagacc agttggatta ccgctttgac caagccagac aagccagcca gttagaccaa
    11101 aaagatttgg aagtggctgt cagcgaccgt ttgcaagaag tgcggattga attgcaccaa
    11161 ggcctgaccc aagtccgtca agaaatgaca gataatctcc tccaaactag agacaagaca
    11221 gaccaacgtc tccaagcctt gcaggaatca aatgagcaac gtttggaaca aatgcgccag
    11281 acggtcgagg aaaaactaga aaagaccttg cagacacgct tacaggcttc ctttgaaaca
    11341 gtttctaaac aactggagtc tgtcaatcgt ggccttggag aaatgcagac agttgcccgt
    11401 gatgtcggag ctcttaacaa ggttctctct ggaaccaaga cgcgaggtat tctgggagaa
    11461 ttgcaactgg ggcaaattat tgaagacatc atgacacctg cccagtacga acgagaatac
    11521 gcaacggttg aaaactctag tgaacgagtg gagtatgcca tcaagttacc cggacaaggc
    11581 gaccaagaat acgtctatct gccaattgac tctaagtttc cactggcaga ttattaccgc
    11641 ttggaagaag cctatgagac aggtgacaag gatgagattg aacgctgtcg taagtcactc
    11701 ctagcaagcg tcaagcgctt tgccaaggat atcaagagca agtacatagc accgcctcgg
    11761 acaaccaatt ttggaatctt gtttgttccg acagaaggtc tttattcaga gattgtgcgc
    11821 aatccggtct tctttgatga tttgagacgg gaagaacaga ttatcgttgc aggaccaagt
    11881 accctatcag cccttcttaa ctccctatca gttggtttca agacccttaa tatccaaaag
    11941 agtgccgacc atatcagcaa gactcttgcc agtgtcaaga ccgagtttgg caagtttggt
    12001 ggtattctgg tcaaggcaca aaaacatctc caacatgcct ctggcaatat tgatgaatta
    12061 ttaaaccgtc gtaccatagc tatcgagcgg acgctccgtc acattgagtt gtcagaaggt
    12121 gagcctgcgc ttgatctact ccattttcaa gaaaatgagg aagaatatga agattagtca
    12181 catgaaaaaa gatgagttat ttgaaggctt ttacctaatc aaatcagctg acctgaggca
    12241 aactcgagct gggaaaaact acctagcctt taccttccaa gatgatagtg gcgagattga
    12301 tgggaagctc tgggatgccc aacctcataa cattgaggcc tttaccgcag gtaaggttgt
    12361 ccacatgaaa ggacgccgag aagtttataa caatacccct caagtcaatc aaattactct
    12421 ccgcctgcct caagctggtg aacccaatga cccagctgat ttcaaggtca agtcaccagt
    12481 tgatgtcaag gaaattcgtg actacatgtc gcaaatgatt ttcaaaattg aaaatcctgt
    12541 ctggcaacgg attgtccgaa atctctacac caagtatgat aaggaattct actcctatcc
    12601 agctgccaag accaaccacc atgcctttga aacgggcttg gcctatcata cggcgaccat
    12661 ggtgcgtttg gcagacgcta ttagcgaagt ttatcctcag ctcaataaga gcctgctcta
    12721 tgcggggatt atgctgcatg acttagctaa ggttatcgag ttgacggggc cagaccagac
    12781 agagtacaca gtgcgaggta atcttcttgg acatatcgct ctcattgata gcgaaattac
    12841 caagacagtt atggaactcg gcatcgatga taccaaggaa gaagtcgttt tgcttcgtca
    12901 tgtcatcctc agtcaccacg gcttgcttga atatggaagt ccagtccgtc cacgtattat
    12961 ggaggcagag attatccata tgattgacaa tctggatgca agcatgatga tgatgtcaac
    13021 agctctggct ttggtggata aaggagagat gaccaataaa atcttcgcta tggataatcg
    13081 ttccttctat aaaccagatt tagattgata atttaagaaa aatgagcatt ttttaggata
    13141 agaatgttcg tttttttatg tgaatatggt ataataagta aaagacaaaa atgaatactc
    13201 ttcgaaaatc tcttcaaact aggatagtat cgccttgtcg tatgtatata tgcaggtata
    13261 ttacagggtt tgtcagttct attgacaatc tcaaaacagt gttttgaacc accagcgacc
    13321 agctttctag tttgcttttt gattttttga ataaaaatgg aataggaaat agaaatgaaa
    13381 ttaagaagaa gtgatcggat ggttgtcatt tccaactatt tgattaataa tccttataaa
    13441 ctaactagtc tcaatacttt tgctgaaaag tatgagtctg ctaaatcatc catctcagaa
    13501 gatatcgtca ttatcaaacg cgcctttgag gaaattgaaa tcggtcatat ccagacagtg
    13561 actggggctg gcggaggtgt catcttcaca ccgtctattt cgagtcagga tgctaaggaa
    13621 atggttgaag acttgcgtac caagttgtca gaaagtgacc gtatcttgcc aggtggttat
    13681 atctatctgt ctgatttgct tagcacacca gccatcttga aaaatattgg tcgtattatt
    13741 gccaaaagct ttatggacca aaaaattgac gcggttatga ccgtagcaac taagggtgtg
    13801 ccacttgcaa atgcagttgc caatgtcctc aatgtctctt ttgtcattgt gcgccgtgac
    13861 ctgaaaatta ccgaaggttc aactgttagc gtcaactatg tttcaggttc aagtggtgac
    13921 cgtatcgaga aaatgttcct ttcaaaacgt agtcttaagg caggcagccg tgtcttgatt
    13981 gtggatgact tcttgaaagg tggcggaacg gtcaatggta tgattagtct cttgcgcgag
    14041 ttcgactcag aactggcagg tgtagcggtc tttgcggaca atgcccaaga agaacgtgaa
    14101 aagcagtttg actacaagtc actcttgaag gtaaccaata ttgatgtcaa gaaccaagcc
    14161 atcgatgttg aggttggcaa tatctttgac gaagataaat aagagataga actaaaggtt
    14221 ggaacgattg tcccagcctt tctttgcaaa cagaatagaa ggaagcttat gaaaacacca
    14281 tttatcaata gagaagagtt agaagcgatt gttgccgagt tcccgactcc ctttcacttg
    14341 tatgatgaga aggggattcg tgagaaggca agagccgtca accaagcttt ttcgtggaac
    14401 aagggcttta aggaatattt tgcagttaag gctactccaa ctccagctat tttgaaaatt
    14461 ctccaagaag aaggttgtgg tgtggactgc tctagttatg tagagctttt gatgagccat
    14521 aaactggact ttctgggttc tgagattatg ttctcttcca acaacacgcc agacaaggaa
    14581 tacgcctatg cacgtgaatt gggtgcgacc attaacttgg atgcctttga agatattgaa
    14641 catctggaga gagtagcagg cattccagaa atcatctctt gtcgttataa tcctggaggc
    14701 gtttttgaac tggggacaga cattatggac aatcctgggg aggctaagtt tggcatgacc
    14761 aaggaccagc tctttgaagc ctttgctatc ttgaaggaaa aaggagccaa gacttttggg
    14821 attcactcct tcctagcgtc caataccgtg acccatctct attatccaga gttggctcgt
    14881 cagctctttg aactggctgt tgaaatcaag gaaaagttgg gcatttcgct agactttatc
    14941 aatctttctg gcggtattgg tgttaattat cgtccagacc aggagccgaa cgatatcgcc
    15001 ttgattggtg agggagttcg taaggtgtat gaagaagttc ttacgtcagc aggtcttggt
    15061 caggtcaaga ttttcaccga attgggtcgt tttatgctgg cacctcacgg tgctctagtc
    15121 acaagagtga ctcataagaa ggaaacctac cgtacctatc taggtgtgga tgcctcagca
    15181 gtcaacctca tgcgtccagc tatgtacgga gcttaccatc atattagcaa cgtgacccat
    15241 ccagatggac cagctgaagc ggtagatgtg gttggttcac tctgtgaaaa caatgataaa
    15301 tttgcagtga atcgcgaact gcctcataca gaaatcggtg atttgctggt aattcatgat
    15361 acaggtgccc acggattttc aatgggctac cagtataatg ccaaattacg ttctgcggaa
    15421 atcctctata ccgaagaagg taaagcccgt caaatccgcc gtgcagagcg ccctgaggac
    15481 tattttgcaa ccttatatgg cttcgatttt gaagaataat ctgataatag attgaaaatg
    15541 aaattgaaaa acagattgct ttctaaaaaa taggcaaaaa tcttgttttt ccttcaagtc
    15601 gtgatataat aaaactataa aacgttttca aggaaggtaa cgatatgtct gaagaaacaa
    15661 ttgattatgg acaagtgaca ggaatggtgc attcgacaga aagctttggg tcagtagatg
    15721 ggcctggtat tcgctttatt gtctttttgc agggctgtca catgcgttgc cagtattgcc
    15781 acaacccaga cacttgggct atggagtcca ataagtcacg tgaacggaca gtagatgatg
    15841 tcttgacaga ggccttgcgc taccgtggtt tctggggaaa taagggtggg attacagtca
    15901 gtggaggaga agctctcttg cagattgatt tcctgattgc tctcttcacc aaggctaagg
    15961 aacaaggaat ccactgtacc ttggatacct gtgctcttcc tttccgtaat aaaccacgtt
    16021 accttgagaa gtttgacaaa ctcatggctg tcactgactt ggttcttttg gatatcaagg
    16081 aaatcaacga agaacagcac aagattgtca ctagccaaac taataaaaat atcttggctt
    16141 gtgcccagta tctatcagat attggaaaac ctgtctggat tcgccacgtg ctagttccag
    16201 gattgacaga cagagatgat gacttgattg aacttggtaa gttcgtcaag accctcaaaa
    16261 atgttgataa gtttgaaatt ctaccttatc acaccatggg tgagttcaag tggcgtgaac
    16321 ttggaattcc atattccctc gaaggagtca aaccaccaac agcagatcgc gtcaagaacg
    16381 ctaaaaaact catggatacc gaaagttatc aagattatat gaaacgtgta catggataga
    16441 aaagaagcct gatggaaaca tcgggctttt gatttgcaaa aagacttagc aaatcagcta
    16501 agcctttttc ttcttatctc gaacgttgtt ttccagcgtt gcgatttttg tgttttttct
    16561 tgcttgtgat agcagttggt tgttcagggg taacgtcttt tcgtccactt ggtttagaga
    16621 aagcacttgc ttttggtggg ttcttggcta gttcttcacg gacttttttg cgaagttttg
    16681 gacgaacgat atagttgacg ataaactgtt ggagaatcat catgaaacca ccgacaaccc
    16741 agtaaagtgt gacactagct ggtgagaaga gggagaagac gacgatcatg agtgggctca
    16801 tgtaaatcat tttcttgatt tgttctcttt gcatttcatc ttctactccg tgaagtgaaa
    16861 ggagcgattg aagatagtaa aggacaccag cacaggcaac caaaatcata cttggagaac
    16921 ctagaggaat gcctaggtag cttgcttgag caaccccttc agtatgttgg gcagcaaagt
    16981 agatagcaga gaagaaaggc atttgaagga ggatagggaa acatcctaca ccgccaaaca
    17041 tgctgatacc gtgctctttt tgagcggcaa agagggcttg ttgggcttcg agtttttctt
    17101 cttgagtagt tgcttctttg agacgtgttt ggtgtggctc aaggacatgc ttgagagcgt
    17161 tcatcttttc agagtgaagc gttgccttcc atgattggta gataccaagt ggtaagataa
    17221 tcaagcgtac gataatggtt acgataatga tagcgacacc aaagcctaga cctttatcag
    17281 tagcgaagta cttgatggct tcagccatag gcgctccgat cgtattccaa ataaatcctg
    17341 ttggctgacc tgtggtttta tcgacattga cacagccagt caagacaagc aacatagcca
    17401 ctcccatagc cgagaatgca aaacgtttaa tagatttcac tgtttttatt ccttctttaa
    17461 aaattatacc tttctattct actgtttttt tacaaaatat acaatagttc tggagaccta
    17521 atttgcgatt ttaaagtcag agtagggagg aaagttgctt agtttgacat ctaagtagct
    17581 tacttttgaa aaaggtgtcg gtccttttcg gatttcttgg ataaattttg ccatgatagc
    17641 agatgagtct gcttgggcta agatttccac tgtgccatcg tcgttattcc atacccgacc
    17701 tgtgatgcca ccgatttcaa gggccaggct ataaacaccc caacgaaagc cgactccctg
    17761 caccctacct tgggcaatca ttctaacctt ttgcatacca aacccctttg attgtgttat
    17821 aatatttcta tgactattat aacctcaaaa gccaattctg tggtaaaaaa tgctaagaaa
    17881 ttacaccaaa aaaaataccg caagtctgcc tatttgattg aaggctggca cttgtttgaa
    17941 gaagctgtcc aagctggagt gacgattgag aaaatctttg ccctagaaaa ttatcgaaat
    18001 cagttagctg cttttccgca aactgtctgg atttcagagg atattttgct agatttggcg
    18061 gattctcaga ctccacaggg aattgttgcc gtggttcaaa aagaagaagt aggacaagct
    18121 gatttgagtc agggcaagtt cttgtttttg gaagatgtgc aagatcctgg taatgtagga
    18181 actatcattc gaactgcgga ggcagcaggt tttacaggag tgattgtttc agataagtcg
    18241 gcagacatct acagtctcaa aaccctacgt tccatgcaag gtagtcattt ccatctgccc
    18301 atttaccgga tgactagtca agcgcttctt gacgaaacta aaaaggtagc tatcccagtg
    18361 ctagcaacaa ccctatctaa agattctgtt gattacagag aactgccttc tatagaaaat
    18421 tttgtactag ttatgggaaa tgagggtcaa ggaattagtc cccttatggc tgaaagtgca
    18481 gaccagttgg tccatattag catgaagggg caggccgaga gtttgaatgt tgcagttgca
    18541 accggtattt taatcttcca tttaagctaa ttttaacttt ttttgttata atcaaggaaa
    18601 gatgttcaca gaaaaggaga aaaggatgaa tcacactatt atacatgacc gtgcaggtct
    18661 caatcaattt tacgctaagg tttatgcctt tgttggtctg ggaatcggac tatctgcttt
    18721 ggtatcaggc cttatgttga cggtctttca gtctcagttg gtttacttgt tgatgcaggg
    18781 gcgtctctgg ttgaccattg ctacttttgc ggagttggct ttggttttcg ttgccagtag
    18841 catggcttca agaaatagtc cagctgctct tccagtattt ttactttact ccgttttaaa
    18901 cggctttacc cttagttttg tggtggcttt ctatactccg ggtacagttt tatctgcctt
    18961 tgtatcgagc gcccttctct tctttgtcat ggcggcagtt ggtattttta ccaagaaaga
    19021 cttgagtggg attggtcgag caatgatggc agctctcatt ggtttactga ttgctatggt
    19081 agtcaatatt ttcttggcta gtggcttctt tgattatatg attagcgtag ccatggtttt
    19141 ggttttttca gggttgattg cttgggataa ccaaaagatt cgcctcgcct atgaacaatc
    19201 acaaggtcgt gtagcgacag gctgggtggt gtcaatggct ctcagcatct atcttgattt
    19261 tatcaatctt ttcctaagta ttctacgtat ctttggtcgc aatgactaaa aggtctatga
    19321 aatcagtgtt ttgagtgaca ctgatttttt taaattttct cttttctttt cttggaaata
    19381 ggtgtataat acgtttatta aatttttgag gagttgtcta tgaagaaaag ttttatccat
    19441 caacaagaag aaatttcctt tgtcaaaaat acttttaccc agtatttgaa agataagcta
    19501 gaagttgtcg aagttcaagg tcctatcttg agtaaggtcg gtgacggaat gcaggacaac
    19561 ctgtctggtg tggaaaatcc agtatcggtc aaggttctcc aaatccctga tgctacttat
    19621 gaagtggtgc actcacttgc taaatggaaa cgccacacct tggctcgttt tggctttggt
    19681 gaaggagagg gtctctttgt ccacatgaaa gcccttcgtc cagatgagga ttccttggat
    19741 gcaacccact ctgtttatgt tgaccagtgg gactgggaga aggttatccc aaatggtaag
    19801 cgtaacatcg tttatctaaa agaaacagtt gagaagattt ataaggctat tcgcctgact
    19861 gagctagctg ttgaagcccg ctatgacatc gagtctatct tgccaaaaca aatcaccttt
    19921 atccatacag aagaattggt agaacgctac ccagacttga cacctaaaga acgtgaaaat
    19981 gcgatttgta aagaatttgg agccgtcttt ttgattggta tcggtggcga gttgccagat
    20041 ggtaaaccgc acgatggacg tgcaccagac tatgatgact ggacaagcga gtctgagaat
    20101 ggctacaagg gtctaaatgg tgatattctt gtctggaatg agtctttagg tggagccttt
    20161 gagttgtctt ctatgggaat tcgtgtagat gaagaaactc ttagacgtca ggtggaaatt
    20221 acaggtgatg aagaccgctt ggaattggaa tggcacaagt ctttgttgaa tggcctattc
    20281 ccattgacaa tcggtggagg aattggacaa tctcgtatgg ccatgttcct acttcgcaag
    20341 agacacatcg gagaagtgca aacaagtgtt tggcctcaag aagtccgcga tacttacgaa
    20401 aatattttgt agagaatcga accgcaaggt tcggttttct ttctcttttt gtctataatt
    20461 tggtataata aacagtatga aaatcgtatc aggaatctat gggggacgtc ccctcaagac
    20521 actagaaggc aagacaacaa gacctacttc ggataaggtt aggggagcca tttttaacat
    20581 gattggtccc tactttgaag ggggacgagt cttggacctt tatgcaggta gtggtggttt
    20641 atctatcgaa gcagtatcgc gtggcatgtc cagtgctgtt ttggtggagc gagaccgtaa
    20701 ggctcagacc atcgtggctg aaaatatcca gatgaccaag gaagttggaa aatttcaact
    20761 cctcaagatg gatgcagaga gggcattgga acaggtatct ggggaatttg acctcgtttt
    20821 cttagaccct ccctatgcca aggaacaaat cgtagcagat attgaaaaaa tggctaagag
    20881 agagcttttt tctgaagatg ttatggttgt gtgcgagacg gataaggccg ttgaacttcc
    20941 agaagagatt gcctgtctgg gtatctggaa ggaaaagatt tatggaatta gtaaggtgac
    21001 agtctatgtc agataagatt ggcttattca caggctcatt tgatccgatg acaaatgggc
    21061 atctggatat cattgaacgg gcgagcagac tttttgataa gctttatgtg ggtatttttt
    21121 ttaatcccca caaacaagga tttctccctc ttgaaaatcg taaacggggg ctagaaaagg
    21181 ctttgggaca tttggaaaat gttgaagtcg tggcttctca tgatgaattg gtggtcgatg
    21241 ttgcaaaaag actgggggct actttcctag tacgggggtt gaggaatgcg gcggatttgc
    21301 aatatgaagc tagttttgat tactacaatc atcagctgtc ttctgatata gagactattt
    21361 atttacatag ccggcctgaa catctctata tcagttcatc aggtgttcga gagcttttga
    21421 agtttggtca ggatattgcc tgccatgttc ccgagagtat tttggaggaa ataagaaatg
    21481 aaaaaaaaga ttagatggcc cttatacgtc attgcggcct tgattgtgac tttcttggca
    21541 tttgtagtgc ccttgcctta ttatatagag gttccaggtg gttcggaaga tattcgccaa
    21601 gtccttaaag taaatgacac agaagataag gaagctggtg cctatcaatt cgttacggtt
    21661 ggtgttcaac atgccacttt agctcatatg atttatgctt ggttgacacc ttttacagat
    21721 attcgtagtg ctcaggagac tacaggtggt tcttccgatg ttgaatttat gcgaatcaat
    21781 caattctaca tgcaaacatc gcaaaatatg gccaagtatc aaggactaaa aacagctggt
    21841 aaggatatcg aactcaagta ctttggagtt tatgttttga atgtgacgga taattcaacc
    21901 tttaaagaga ttctcaatat ctctgataca gtcacagcag tcaatgatca gacctttgat
    21961 agttccaaag acttgattga ttacgtcagt tctcaaaaat taggggattc cgtcaaggtc
    22021 acctatgaag aggatgggca aaccaagtct gcagaaggaa aaatcatcac cttggaaaat
    22081 ggcaaaaatg gaattggaat cggcttgatt gaccgtacag aggtaatcag caatgtccca
    22141 attagctttt caacagctgg tattggcggt ccaagtgctg gtctcatgtt tagtctagct
    22201 atctatactc aaatagctca cccagatctt cgtaatggtc gtattgttgc cggtacaggt
    22261 accattgacc gcgatggtaa tgtgggagac attggaggta ttgataagaa ggttgtagct
    22321 tcggctaggg caggtgctgc tattttcttt gctcctgata accctgttag cgaagaagaa
    22381 caaaaggcgc atccggacgc gaaaaacaac taccaaacag ccctagaagc ggctaaaaca
    22441 atcaagacgg atatgaaaat cgtgcccgtt aaaaccctac aagatgcgat tgattacttg
    22501 aaaaacaatc cctaattttt gagtgaagtt tccaaactag cgcacaaaca gagaagatgg
    22561 tataatagtc aaatggttca attattattc actctaagta gtcatatgtt ctttatttat
    22621 gtgagttttt accttttaaa ggatcttgtt agatgggaga aggttttaaa agtgacagat
    22681 gataatacaa gaaaagttcg tttattagta gcctttttta gcattgtcat aggctacatc
    22741 ctgagttctt tctttattag cctgtatcat ttgtggcaag aagcgcttag aggattatta
    22801 tgaaatcaag agtaaaggaa acgagtatgg ataaaattgt ggttcaaggt ggcgataatc
    22861 gtctggtagg aagcgtgacg atcgagggag caaaaaatgc agtcttaccc ttgttggcag
    22921 cgactattct agcaagtgaa ggaaagaccg tcttgcagaa tgttccgatt ttgtcggatg
    22981 tctttattat gaatcaggta gttggtggtt tgaatgccaa ggttgacttt gatgaggaag
    23041 ctcatcttgt caaggtggat gctactggcg acatcactga ggaagcccct tacaagtatg
    23101 tcagcaagat gcgcgcctcc atcgttgtat tagggccaat ccttgcccgt gtgggtcatg
    23161 ccaaggtatc catgccaggt ggttgtacga ttggtagccg tcctattgat cttcatttga
    23221 aaggtctgga agctatgggg gttaagatta gtcagacagc tggttacatc gaagccaagg
    23281 cagaacgctt gcatggcgct catatctata tggactttcc aagtgttggt gcaacgcaga
    23341 acttgatgat ggcagcgact ctggctgatg gggtgacagt gattgagaat gctgcgcgtg
    23401 agcctgagat tgttgactta gccattctcc ttaatgaaat gggagccaag gtcaaaggtg
    23461 ctggtacaga gactataacc attactggtg ttgagaaact tcatggtacg actcacaatg
    23521 tagtccaaga ccgtatcgaa gcaggaacct ttatggtagc tgctgccatg actggtggtg
    23581 atgtcttgat tcgagacgct gtctgggagc acaaccgtcc cttgattgcc aagttacttg
    23641 aaatgggtgt tgaagtaatt gaagaagacg aaggaattcg tgttcgttct caactagaaa
    23701 atctaaaagc tgttcatgtg aaaaccttgc cccacccagg atttccaaca gatatgcagg
    23761 ctcaatttac agccttgatg acagttgcaa aaggcgaatc aaccatggtg gagacagttt
    23821 tcgaaaatcg tttccaacac ctagaagaga tgcgccgcat gggcttgcat tctgagatta
    23881 tccgtgatac agctcgtatt gttggtggac agcctttgca gggagcagaa gttctttcaa
    23941 ctgaccttcg tgccagtgca gccttgattt tgacaggttt ggtagcacag ggagaaactg
    24001 tggtcggtaa attggttcac ttggatagag gttactacgg tttccatgag aagttggcgc
    24061 agctaggtgc taagattcag cggattgagg caagtgatga agatgaataa gaaatcaagc
    24121 tacgtagtca agcgtttact tttagtcatc atagtactga ttttaggtac tctggctcta
    24181 ggaatcggtt taatggtagg ttatggaatc ttgggcaagg gtcaagatcc atgggctatc
    24241 ctgtctccag caaaatggca ggaattgatt cataaattta caggaaatta ggctggagaa
    24301 ccagcctttt tctaaagata aggagaaata tgaacaaaaa aacaagacag acactaatcg
    24361 gactgctagt gttattgctt ttgtctacag ggagctatta tatcaagcag atgccgtcgg
    24421 cacctaatag tcccaaaacc aatcttagtc agaaaaaaca agcgtctgaa gctcctagtc
    24481 aagcattggc agagagtgtc ttaacagacg cagtcaagag tcaaataaag gggagtctgg
    24541 agtggaatgg ctcaggtgct tttatcgtca atggtaataa aacaaatcta gatgccaagg
    24601 tttcaagtaa gccctacgct gacaataaaa caaagacagt gggcaaggaa actgttccaa
    24661 ccgtagctaa tgccctcttg tctaaggcca ctcgtcagta caagaatcgt aaagaaactg
    24721 ggaatggttc aacttcttgg actcctccag gttggcatca ggtcaagaat ctaaagggct
    24781 cttataccca tgcagtcgat agaggtcatt tgttaggcta tgccttaatc ggtggtttgg
    24841 atggttttga tgcctcaaca agcaatccta aaaacattgc tgttcagaca gcctgggcaa
    24901 atcaggcaca agccgagtat tcgactggtc aaaactacta tgaaagcaag gtgcgtaaag
    24961 ccttggacca aaacaagcgt gtccgttacc gtgtaaccct ttactacgct tcaaacgagg
    25021 atttagttcc ctcagcttca cagattgaag ccaagtcttc ggatggagaa ttggaattca
    25081 atgttctagt tcccaatgtt caaaagggac ttcaactgga ttaccgaact ggagaagtaa
    25141 ctgtaactca gtaaaagata agcctaaact cctatgtcac ttatggatgt aggagttctt
    25201 tttactagtt taagcagggc tagaacaggt actaagaaaa aatagtaact tctaaaacta
    25261 acttccagtt tcccacaacc tagcttttag tatgagaaaa acgcgtgaaa tcagtggaaa
    25321 tccgtcttag actaacttcc agttttggga gagagatgga agttacgcta agaaaaaaat
    25381 aatatgtatt ggattaaatt ttgtgatata ataaaggata agatactatt ttaggagaag
    25441 aactatggaa gacccaagta gtcagaattt gttgctacaa tttgttttat tgtttatctt
    25501 gacggtatta aatgcctttt tctcagccac agaaatggcc atggtttctc ttaatcgtgc
    25561 ccgagttgaa caaaaggcgg aagaaggaga cagacgctac attcgcctgc tgaaggtact
    25621 agaaaatcct aaccactttt tatcaaccat tcaggtagga atcaccctga ttacaatctt
    25681 atcaggggcg agtttaactg atactctagg acgtgtgatt gcctcttggc ttgggaatgg
    25741 cgaaacagca caagccgtgg caacttttct atccttggca tttttgacct atatttccat
    25801 cgtttttggg gaattatatc ctaagagaat cgctcttaat ctaaaggatg ccttggcaat
    25861 tcgtacagcg ccggttatca ttgggatcgg aaaactagtc agtccttttg tttggctttt
    25921 agctgcttcg accaatttct tgagccattt gactcctatg tcattcgatg atgcggatga
    25981 aaagatgacc cgtgatgaaa ttgcctatat gctgacaaat agtgaagaaa cattggatgc
    26041 tgatgagatt gagatgctac aaggtgtctt ttcgctcgat gaactgatgg cacgagaggt
    26101 tatggttcct cgaacggatg cctttatggt ggatattcag gatgatagtc aagccattat
    26161 ccaaagtatt ttaaaacaaa attattctcg tatcccggtt tatgatgggg ataaggacaa
    26221 tgtaattgga atcattcaca ccaagagtct ccttaaggca ggctttgtgg acggttttga
    26281 caatattgtt tggaagagaa ttttacaaga tccacttttt gtacctgaaa ctatttttgt
    26341 ggatgacttg ctaaaagaac tgcgaaatac ccaaagacaa atggcaatct tgctggatga
    26401 atacggtggt atggctggtt tagtgacttt ggaagacctc ttagaggaaa ttgttggtga
    26461 aattgatgat gaaacggata aagcagcaat agatgttcat cagattggcg aggataccta
    26521 cattgttcaa ggaactatga ccctcaatga tttcaataat tactttgatg ttgaactgga
    26581 aagtgatgac gttgatacca tcgctggtta ttatttgaca ggagtgggaa ccattccaac
    26641 gactgagaaa ctcagctatg aattggtcag ccaaaacaaa cagtttatct taaccaatga
    26701 taaagtgaag aatggacgtg ttaccaaggt aaaagtccaa atcacagaag tcgaaataga
    26761 agaagaaaca gaataaacta gaggcttttg tcaccaggcg tgacgaagct tttttcaatt
    26821 gatttcaaaa gggaattatg ccatggaaag aactctgcca caaactcgct ccaaaagttt
    26881 ttaaagttat acgtatttat tcgagggaaa ataagaaaag cccttcaaat tgggctttct
    26941 gttcatttga aacctgataa atcaagttat agaaggcggt agacggattt gaaccgacga
    27001 tcaagctttt gcagagccgt gccttaccac ttggctatac cgccttaacg tttattatta
    27061 taccttgaaa atgattttca gtcaatagtt ttttcagttt tttgtaccat agcgtgattc
    27121 gaatgtgatg ccaagttttc tatgggaaaa aatttacaaa aaacctactg aaaccccttg
    27181 aaaaatctag ctaaataggg tataatatgg gtaatcattt gtcgtaggtt ttgtctgaaa
    27241 tattgtccag acaaggctca cagcagttaa atcttctgaa aaagtcagat ttagctgctc
    27301 tttttgtgct ttttttcaag attttgagca tttgtaacag aggcttaaag attctgaaaa
    27361 atcgtcaaga ggacacggtg ataaggggtt tacaaccata tgacgattag aaaagcctga
    27421 ttgacaaggc ttggaactta tttacaaagg agaatcatct tggcaggaca tgacgttcaa
    27481 tacgggaaac atcgtacccg tcgtagtttt tcaagaatca aagaagttct tgacttacca
    27541 aatttgattg aaattcaaac tgactcattc aaagctttcc tagaccacgg tcttaaggaa
    27601 gtgtttgaag atgtattgcc aatttcaaac ttcacagaca caatggagtt ggaatttgtt
    27661 ggatatgaaa tcaaggaacc aaaatacacg ctagaagaag ctcgtatcca cgatgctagc
    27721 tactcagcac caatttttgt aaccttccgt ttgatcaata aagaaacagg cgaaatcaag
    27781 acccaagaag ttttctttgg tgatttccca atcatgacag aaatgggtac tttcatcatc
    27841 aatggtggtg aacgtattat cgtttctcag ttggtccgct caccaggtgt ttactttaac
    27901 gacaaagtag acaaaaatgg taaggtgggc tatggttcaa ctgttatccc taaccgtgga
    27961 gcttggttgg aacttgaaag cgactcaaaa gatatcacct acactcgtat cgaccgtact
    28021 cgtaagattc catttacaac cttggttcgt gctcttggtt tctcaggtga tgatgaaatc
    28081 tttgatatct ttggtgacag cgaattggtt cgcaacactg ttgaaaaaga tatccacaag
    28141 aatccaatgg actctcgtac agacgaagcc ttgaaagaaa tttacgaacg ccttcgtcca
    28201 ggtgagccta agacggctga aagctcacgt agcttgcttg tggctcgctt ctttgaccca
    28261 cgtcgctatg acttggcagc agttggtcgt tacaaaatca ataaaaaact caatgttaaa
    28321 acacgtttgc tcaaccaaac cattgcagag ccattggtag accctgaaac tggagaaatc
    28381 ttggtagaag ctggtacgat tatgactcgt agcgtgattg aaagcattga aagccatttg
    28441 gatggcgact tgaacaagat tgtctacatc ccaaacgatg cagccgttgt gactgagcct
    28501 gttgttcttc aaaaattcaa ggttgttgct ccaactgatc cagatcgcgt cgtaacgatc
    28561 attggtaatg ctaacccaga tgacaaggtt cgtacggtga ctcctgcaga tatccttgct
    28621 gagatgagct acttcctcaa cttggctgaa ggacttggcc gtgtagatga tatcgaccac
    28681 cttggaaatc gtcgtatccg tgcggttggt gaattgcttg ccaaccaagt acgtttggga
    28741 ctttctcgta tggaacgtaa tgtccgtgaa cgtatgtctg ttcaggacaa tgaagtcttg
    28801 acaccacaac aaattatcaa tatccgtcct gtaacagctg cagttaaaga attctttggt
    28861 tcatcacagt tgtcacagtt catggaccaa cacaacccgc tttctgagtt gtctcacaaa
    28921 cgccgtttgt cagccttagg acctggtggt ttgactcgtg accgtgccgg atatgaagta
    28981 cgtgacgtgc actacactca ctatggtcgt atgtgtccaa tcgagacacc tgaaggacct
    29041 aacatcggtt tgatcaataa cttgtcatct tacggacact tgaacaaata tggttttgtt
    29101 caaacaccat accgtaaggt tgaccgtgaa acaggtgttg tcacgaacga aattgtttgg
    29161 ttgacagctg atgaagaaga tgaatatact gtagctcagg ctaactctcg tctgaatgaa
    29221 gatggaacct ttgctgagaa gattgtcatg ggacgtcacc aaggggtcaa ccaagagtat
    29281 ccagctaata ttgttgacta catggacgtt tcaccaaaac aggtagttgc cgttgcgaca
    29341 gcatgtattc ctttcttaga aaacgatgac tccaaccgtg ccctcatggg agccaatatg
    29401 caacgtcagg ctgtgccatt gattaatcct caggcacctt acgttggtac tggtatggaa
    29461 taccaagcag cccacgattc tggtgcggct gtgattgctc agtatgatgg taaagttact
    29521 tacgcagatg ctgacaaggt agaagttcgt cgtgaagatg gttcattgga tgtttaccac
    29581 atccaaaaat tccgtcgttc aaactcaggt actgcttaca accaacgcac tctcgtaaaa
    29641 gttggtgatg tcgttgaaaa aggcgatttc atcgctgacg gaccttctat ggaaaatgga
    29701 gaaatggcgc ttggacaaaa cccaatcgtt gcctacatga cttgggaagg ttacaacttc
    29761 gaggatgccg ttatcatgag cgaacgcttg gtgaaggacg atgtctacac atctgttcac
    29821 cttgaagaat acgaatcaga aacgcgcgat acaaagcttg ggcctgaaga aatcactcgt
    29881 gaaattccaa acgttggtga agatgccctc aaagaccttg acgaaatggg gattatccgt
    29941 attggtgctg aggttaaaga aggtgatatt cttgtaggta aagtaacacc taagggtgag
    30001 aaagatcttt cagctgaaga acgtctcttg cacgctatct ttggagacaa gtctcgtgaa
    30061 gtgcgtgata cttctcttcg tgtaccacac ggtgccgatg gtgtcgttcg tgatgttaag
    30121 atctttacac gtgtaaatgg agatgagttg caatcaggtg ttaacatgtt ggttcgtgtt
    30181 tacatcgctc aaaaacgtaa gattaaggtc ggagataaaa tggccggacg tcacggaaac
    30241 aaaggggttg tctctcgtat cgttcctgta gaagacatgc cttaccttcc agacggaact
    30301 ccagtcgaca tcatgttgaa cccacttggg gtgccatcac gtatgaatat cggtcaggtt
    30361 atggagcttc accttggtat ggcagctcgt actcttggta ttcacattgc gacaccagtc
    30421 tttgatggag caagttctga agatctttgg tcaactgtta aagaagcagg tatggatagc
    30481 gatgccaaga caatccttta cgatggacgt acaggtgaac catttgataa ccgtgtttct
    30541 gttggagtca tgtacatgat caaactccac cacatggttg acgataaatt gcatgcgcgt
    30601 tcagtcggac cttactcaac tgttacccaa caaccactcg gaggtaaagc tcagtttggt
    30661 ggacaacgtt tcggtgagat ggaggtttgg gctcttgaag cctacggtgc gtcaaatgtc
    30721 cttcaagaaa tcttgactta caagtcggac gatatcaacg gacgtttgaa agcctatgaa
    30781 gctattacaa aaggcaaacc aattccaaaa ccaggtgttc cagaatcctt ccgagttctt
    30841 gtcaaagaat tgcaatctct tggtcttgac atgcgtgtcc tagacgaaga tgaccaagaa
    30901 gtggaacttc gcgacttgga tgaaggaatg gacgaagatg tcatccacgt agatgacctt
    30961 gaaaaagccc gcgaaaaagc agcccaagag gctaaagcag cctttgaagc tgaagaagct
    31021 gagaaagcaa caaaagcgga agcaacagaa gaagctgctg aacaagaata agcagttcac
    31081 ttagaataga aagggaagaa atagtggttg atgtaaatcg ttttaaaagt atgcaaatca
    31141 ccctagcttc tccaagtaaa gtccgttcat ggtcttatgg agaagtcaaa aaacctgaaa
    31201 caatcaatta tcgtaccttg aaaccagaac gtgaaggact ctttgatgaa gtgatctttg
    31261 gtcctacaaa agactgggaa tgtgcttgtg gtaagtacaa acgcattcgt tacagaggaa
    31321 ttgtttgtga ccgctgtggg gttgaagtaa cgcgtacgaa agttcgtcgt gagcgtatgg
    31381 gacatatcga attgaaagct cctgtatctc acatctggta cttcaagggg attccaagcc
    31441 gtatgggctt gacccttgat atgagccctc gtgccctcga ggaagttatc tactttgcgg
    31501 cttatgtggt gattgatcct aaggatacac cacttgagca caagtctatc atgacagagc
    31561 gcgaataccg agagcgcttg cgtgaatatg gttatggttc atttgttgcc aagatgggtg
    31621 cggaagccat ccaagacctt ttgaagcaag tagatcttga aaaagaaatt gctgaactca
    31681 aagaagaatt gaaaacagct actggacaaa aacgtgtcaa agccatccgt cgtttggatg
    31741 ttttggatgc cttttacaag tctggaaaca aacctgaatg gatgattctt aacatccttc
    31801 cggttatccc accagatctt cgtccaatgt tgcagttgga tggtggccgt tttgcctcat
    31861 ctgacttgaa tgacctttac cgccgtgtta tcaaccgtaa caaccgtttg gctcgtttgc
    31921 ttgagttaaa tgcaccaggt atcatcgttc aaaatgagaa gcgtatgctt caagaagcag
    31981 ttgacgcttt gattgacaat ggtcgtcgtg gtcgtccaat cacaggacca ggtagccgtc
    32041 cattgaaatc attgagccac atgcttaaag gtaaacaggg acgcttccgt caaaacttgc
    32101 tcggtaaacg tgttgacttc tcaggacgtt ccgttatcgc cgttggtcca actcttaaga
    32161 tgtaccaatg tggtgtgccg cgtgaaatgg cgattgaact ctttaaacca tttgtcatgc
    32221 gtgaaatcgt tgcccgtgat atcgtgcaaa acgtcaaagc agctaaacgc ttggtggaac
    32281 gcggagatga gcgtatctgg gatatccttg aagaagtgat taaagaacac ccagtgcttt
    32341 tgaaccgcgc accgaccctt caccgtttgg gtatccaagc cttcgagcca gtcttgattg
    32401 atggtaaggc tcttcgcttg cacccacttg tctgtgaagc ctacaatgct gactttgacg
    32461 gggaccaaat ggccatccac gtaccacttt cagaagaagc acaagcagaa gctcgtatcc
    32521 tcatgctagc tgctgagcac atcttgaacc cgaaagatgg gaaaccggta gttactccat
    32581 ctcaggacat ggttttgggt aactactact tgaccatgga agaagctggt cgcgaaggtg
    32641 aaggaatggt cttcaaagac cgtgacgaag cggttatggc ttaccgcaat ggttatgttc
    32701 acctccactc acgtgttggt atcgcaacag acagcctcaa caagccttgg acagaagagc
    32761 aaagacataa ggtcttgctt acaacagttg gtaaaattct cttcaacgat atcatgccag
    32821 aggggctacc atacttgcaa gaaccaaaca atgccaactt gacagaaggt gttccagcta
    32881 aatacttctt gccacttggt ggagatatca aggaagctat cagcaatctt gagctcaacc
    32941 ctccattcaa gaagaaaaac cttggaaata tcatcgctga aatcttcaaa cgtttccgta
    33001 cgacagaaac ttctgcccta cttgaccgca tgaagaacct cggttaccac cactcaactc
    33061 ttgcaggatt gacagtgggt attgccgata tcccagtcgt tgatgacaag gctgaaatca
    33121 ttgaagaatc acacaaacgt gtcgaacaaa tcaccaaaca attccgtcgt ggtatgatca
    33181 cagacgacga gcgttacaat gctgttacag ctgaatggcg tgctgcccgt gaaaaacttg
    33241 agaaacgctt gattgctaac caagatccta agaacccaat cgttatgatg atggactctg
    33301 gagcccgtgg taacatctca aacttctcac agcttgccgg tatgcgtggt ctgatggctg
    33361 ctccgaatgg acgtatcatg gaattgccaa tcctttcaaa cttccgcgaa ggtttgtcgg
    33421 tattggaaat gttcttctca actcacggtg ctcgtaaagg tatgaccgat acggccctta
    33481 agacagccga ctcaggttac ttgactcgtc gtttggtcga cgttgcccaa gacgttatca
    33541 tccgtgagga cgactgtgga actgaccgtg gtctcttgat ccgttctatc gcagaaggaa
    33601 aagagatgat cgagtctctc gaagagcgtc tcaacggtcg ttacactaag aaaactgtta
    33661 aacatccaga aactggtgca gtgattattg gtccaaatga attgattaca gaagacaagg
    33721 cgcgtgaaat tgtcaatgct ggtgtggaag aagtgactat ccgttctgta tttacatgta
    33781 acactcgtca cggtgtctgc cgtcactgtt acggtatcaa cttggcgact ggtgatgcgg
    33841 ttgaagttgg tgaagcagtt ggtacaatcg ctgcccaatc tatcggggaa cctggtacac
    33901 agcttacaat gcgtaccttc cacacaggtg gggttgcctc aaataccgat atcactcagg
    33961 gtcttcctcg tgtccaagaa atctttgaag cccgcaatcc taaaggggaa gcggttatta
    34021 cagaggttaa aggacaagtt actgctatcg aagaagatgc atcaactcgt accaagaaag
    34081 tctttgttaa gggtgaaact ggcgaaggtg aatatgtcgt tccatttaca gctcgtatgc
    34141 gtgtcgaagt tgggggccaa gtagcgcgtg gtgctgctct gacagaaggt tctatccaac
    34201 caaaacgtct ccttgcagtt cgtgatgtct tgtcagttga aacgtacctt ctcggtgaag
    34261 tacaaaaagt ttaccgtagc caaggggtag aaatcggtga caaacacatc gaggtaatgg
    34321 ttcgtcaaat gatccgtaaa gtccgtgtca tggatccagg tgatacagat cttctcatgg
    34381 gtaccctcat ggatatcaat gactttacag atgccaacaa agatgtcctt atcgcaggtg
    34441 gagttccagc gacaggtcgc ccagtcctta tgggaattac caaagcctca cttgaaacaa
    34501 acagtttctt gtcagcggct tccttccagg aaacaactcg tgtccttact gacgcagcta
    34561 tccgtggtaa gaaagatcat ctccttggac ttaaagaaaa tgttatcatc ggtaagatca
    34621 tcccagctgg tactggtatg gcccgttacc gtaaccttga accacatgct gtcaacgaag
    34681 aagaatacct taatcctcca gtagaggaag aaggaaatga agaaacaaca gaagtagttg
    34741 tggatactgc cgttgaaact gtggaagaaa cagtagaata agagagaatg agagaacccg
    34801 agggttctct cattctctct tctgaaaact ttctccattt ttccacgaaa tgtggtaaaa
    34861 taaaagaaag aagctgacaa aggagacggg tatggaacaa acattcttta tcatcaaacc
    34921 agatggtgta aaaagagggc tagtgggtga agtgttaaag cgcatcgaac aacgtggatt
    34981 tacaatcgaa aaattggagt ttcgttcaca ggtttcagaa gagttgattg accagcacta
    35041 tcaggacttg gttggtcaga gtttttaccc accgattcgt gaattcatga cttcaggtcc
    35101 agttcttgtg ggtgtcattt ctggtcccaa agtaatcgaa acttggcgga ccatgatggg
    35161 tgcaactcgt ccagaagaag ctttaccagg cactattcga ggtgattttg caaaagctgc
    35221 tggagaaaat gagattatcc aaaatgttgt acatggttca gattcagaag agtcagctaa
    35281 gcgagaaatt gctctttggt tttaagagtg gattggctca atcaattggt taaaagctca
    35341 tttgaataga aagtatagtc aattagttta agacatgacg catgatatca aactttttag
    35401 tttttgatat ggtgcgtttt ttgattaagt gactattagt ttgtctcgct ccgttaggtg
    35461 cgagacaaaa aaaacacccg ctatgcgggt gtgcgtcgaa ggttatacca aaaaaactcc
    35521 aaacgcgata caataaaggt gttcaatcca attgtaaagc gaaaggagaa aaatatggca
    35581 caaaaggttc ttttatcctg ttcttgtttc aattgactat atttctatac tttttcttcc
    35641 tttctctgtg aaaatcgcaa gtttttccca ccttttctca atactgaaac aacatctttc
    35701 cagaacttca ataatttctt tttgtgttaa atcattattt aactaaatct ttggaggcaa
    35761 tacgttttca aagctacttt tttaccatag gttttgagcc ttcaacacag attactaagc
    35821 caaaaatgct ctaaattttt gaaattctaa caaattccac tcaactttat catcatcttt
    35881 gactttcaca atatcttcct caaaataaca tggaataaag atagttttct tttaaaacgg
    35941 ttgtaggagg aaaatctctc ctacactatt attgattctg agaggaaatt gcaaaatatc
    36001 atctaccaaa tttt
//
LOCUS       DAVLUM010000012        35575 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLUM010000012 DAVLUM010000000
VERSION     DAVLUM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.012"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(109..1743)
                     /locus_tag="VYN42_000477"
     CDS             complement(109..1743)
                     /locus_tag="VYN42_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461603.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLFMSINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1724..2473)
                     /locus_tag="VYN42_000478"
     CDS             complement(1724..2473)
                     /locus_tag="VYN42_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461604.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCNRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            2652..4106
                     /locus_tag="VYN42_000479"
     CDS             2652..4106
                     /locus_tag="VYN42_000479"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1461605.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4196..6814)
                     /gene="alaS"
                     /locus_tag="VYN42_000480"
     CDS             complement(4196..6814)
                     /gene="alaS"
                     /locus_tag="VYN42_000480"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1461606.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(6836..7321)
                     /locus_tag="VYN42_000481"
     CDS             complement(6836..7321)
                     /locus_tag="VYN42_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1461607.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFQLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7596..7835)
                     /locus_tag="VYN42_000482"
     CDS             complement(7596..7835)
                     /locus_tag="VYN42_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461608.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8088..9158)
                     /locus_tag="VYN42_000483"
     CDS             complement(8088..9158)
                     /locus_tag="VYN42_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1461609.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9155..9928)
                     /locus_tag="VYN42_000484"
     CDS             complement(9155..9928)
                     /locus_tag="VYN42_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461610.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9925..10731)
                     /locus_tag="VYN42_000485"
     CDS             complement(9925..10731)
                     /locus_tag="VYN42_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461611.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10712..11869)
                     /locus_tag="VYN42_000486"
     CDS             complement(10712..11869)
                     /locus_tag="VYN42_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461612.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12029..12934)
                     /gene="murB"
                     /locus_tag="VYN42_000487"
     CDS             complement(12029..12934)
                     /gene="murB"
                     /locus_tag="VYN42_000487"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1461613.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGYFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13046..13803)
                     /locus_tag="VYN42_000488"
                     /pseudo
     CDS             complement(13046..13803)
                     /locus_tag="VYN42_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13813..14544)
                     /gene="budA"
                     /locus_tag="VYN42_000489"
     CDS             complement(13813..14544)
                     /gene="budA"
                     /locus_tag="VYN42_000489"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1461614.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14686..15957
                     /locus_tag="VYN42_000490"
     CDS             14686..15957
                     /locus_tag="VYN42_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1461615.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(15977..16792)
                     /locus_tag="VYN42_000491"
     CDS             complement(15977..16792)
                     /locus_tag="VYN42_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1461616.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTNLESANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(16949..17602)
                     /gene="phoU"
                     /locus_tag="VYN42_000492"
     CDS             complement(16949..17602)
                     /gene="phoU"
                     /locus_tag="VYN42_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1461617.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17614..18372)
                     /gene="pstB"
                     /locus_tag="VYN42_000493"
     CDS             complement(17614..18372)
                     /gene="pstB"
                     /locus_tag="VYN42_000493"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1461618.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(18385..19188)
                     /gene="pstB"
                     /locus_tag="VYN42_000494"
     CDS             complement(18385..19188)
                     /gene="pstB"
                     /locus_tag="VYN42_000494"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1461619.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYGKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19199..20083)
                     /gene="pstA"
                     /locus_tag="VYN42_000495"
     CDS             complement(19199..20083)
                     /gene="pstA"
                     /locus_tag="VYN42_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1461620.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20073..20990)
                     /gene="pstC"
                     /locus_tag="VYN42_000496"
     CDS             complement(20073..20990)
                     /gene="pstC"
                     /locus_tag="VYN42_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1461621.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(20990..21868)
                     /gene="pstS"
                     /locus_tag="VYN42_000497"
     CDS             complement(20990..21868)
                     /gene="pstS"
                     /locus_tag="VYN42_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1461622.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22442..23746)
                     /locus_tag="VYN42_000498"
     CDS             complement(22442..23746)
                     /locus_tag="VYN42_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1461623.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23747..24520)
                     /locus_tag="VYN42_000499"
     CDS             complement(23747..24520)
                     /locus_tag="VYN42_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1461624.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24510..24788)
                     /locus_tag="VYN42_000500"
     CDS             complement(24510..24788)
                     /locus_tag="VYN42_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1461625.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24788..25189)
                     /locus_tag="VYN42_000501"
     CDS             complement(24788..25189)
                     /locus_tag="VYN42_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1461626.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25398..26015)
                     /locus_tag="VYN42_000502"
     CDS             complement(25398..26015)
                     /locus_tag="VYN42_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1461627.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            complement(26005..26778)
                     /locus_tag="VYN42_000503"
     CDS             complement(26005..26778)
                     /locus_tag="VYN42_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1461628.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26789..27526)
                     /locus_tag="VYN42_000504"
     CDS             complement(26789..27526)
                     /locus_tag="VYN42_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1461629.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(27531..28661)
                     /locus_tag="VYN42_000505"
     CDS             complement(27531..28661)
                     /locus_tag="VYN42_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1461630.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28745..29134)
                     /locus_tag="VYN42_000506"
     CDS             complement(28745..29134)
                     /locus_tag="VYN42_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1461631.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29150..29533)
                     /locus_tag="VYN42_000507"
     CDS             complement(29150..29533)
                     /locus_tag="VYN42_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1461632.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29534..30322)
                     /locus_tag="VYN42_000508"
     CDS             complement(29534..30322)
                     /locus_tag="VYN42_000508"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1461633.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(30315..31250)
                     /locus_tag="VYN42_000509"
     CDS             complement(30315..31250)
                     /locus_tag="VYN42_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1461634.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31380..31556)
                     /locus_tag="VYN42_000510"
     CDS             complement(31380..31556)
                     /locus_tag="VYN42_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1461635.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31696..32403)
                     /locus_tag="VYN42_000511"
     CDS             complement(31696..32403)
                     /locus_tag="VYN42_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1461636.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32554..33582
                     /gene="queA"
                     /locus_tag="VYN42_000512"
     CDS             32554..33582
                     /gene="queA"
                     /locus_tag="VYN42_000512"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1461637.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34243..34632)
                     /locus_tag="VYN42_000513"
     CDS             complement(34243..34632)
                     /locus_tag="VYN42_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1461638.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(34686..35378)
                     /locus_tag="VYN42_000514"
     CDS             complement(34686..35378)
                     /locus_tag="VYN42_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1461639.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT        10598 a         8122 c         6747 g        10108 t
ORIGIN      
        1 attcctccct atatttttga ttaccaatct taatcattta caactacatt ctaacaaact
       61 ataaaagcgt ttgtcgaatt gaatttatca agcaagcaac caactatctc atcttttttc
      121 tatttctgcc aatatgcgtg acaggtaata atgatagcca aaaatagcaa gagcaagcaa
      181 gacgataaga gctcctactc ccaagttgat ggcaaggata ggggagagag actgaaccaa
      241 gaatatgctc ccaattacaa gggccatcag gattgcacta taaataaaca ataaaactat
      301 ggcgactatg ccatttgaac gattcaccag gtccgtaatg ctactccaat tggttgacag
      361 atttttaacg tccttaaagt aatggtggca agaaaggatg acactggcaa tgatccagac
      421 tacaagaagg taaatcatcg aaaggatgga caagcctaga tatagagaaa gaccgagcaa
      481 agtcagaatt ggtaaaaagg actgaacagc aaagataatc caaaatttca ctttcacata
      541 acgagcaaag tcaaagggta aactcttcag aaaatcaaca ttttccctct ccaaggacaa
      601 ggcaattgaa tgcaggctgg tgatattgtt attgacaact gctataaaca ctcctacaaa
      661 aaacaagggt aaccagtatg gaggatgaat gtctggaact atctgagaat ctcggatttt
      721 ggaaatcaga ctgatcatca tgagataagg aaggaaagca cttgtaaaaa gcactgtaac
      781 cacgccagta ccctgtccca agagggtgag gtggtagcgt aaaaccatgc ggaaaaatcc
      841 ctttttagtg gttgaaattc tctccttgct gcgacgttct tttttgacct tctcctcact
      901 attaagcagg atcacgtcat aaaaacgagg aaggaccttc tttttggtca gataaagcag
      961 gaagagagtt agtcctatcc aagcgagcag acccactaag gcttctgtcg aaaaaggctc
     1021 cactgctatt ttgtaaaaga tatgaagagg ataaagaaga aatggaatgt ctctaacttt
     1081 gtcaacaata cttccaaaag tcgactgaag aaagaagata aatattaaag gtatgagaac
     1141 tcctatccca atcatcacat tcgaaaaaat agactgatac tttctgaaga ccctagtctg
     1201 agccaagaaa tgtactgcca ctaccgtcac taaagtaaca gagacaaata ataaggtcaa
     1261 ggacagtagc atcaaaggca aacccagcca aagagaagga gctagactaa tatagagggc
     1321 tagaaaataa gctaggattg gtacaattcc agttagagct ggcaagagga cagacagacc
     1381 tttggccatt ataatctctg attctttaaa ggcatagggc ctataggagg ccaggtcctt
     1441 actctcataa aagacattgt aaaatgcagt gaaagaagtt gaaaaggcca gcaccagtaa
     1501 aatagcaacc atcgtactaa aaaaacttgg catttcctca aaaggaaaac gaaaggctat
     1561 atttatagac atgaaaagca tcaagagact agaaaaaatg taagaactta ggactctagc
     1621 ggaaacattt acttttttcc caggattctt agcctgcttc tttcgtagat tagccagatt
     1681 agcttcttga gatgaataga ggatattgat atcaactaat tttttaatga ccttgagacg
     1741 catccgcaac ctcctctttt ctaccagcaa gactaaggta gatactttcc aaagactggt
     1801 ctgggtggtc tttcctcaag ttctctacac taccacaata gatcaaatgc ccctttttca
     1861 aaatggcaat ccgattacag acttgctcgg ctacctctag gacatgagtt gaaaacaaga
     1921 ccgtcttccc tttttgtgca tgttccttca tcatctgttt caaatcaaag gcagcctggg
     1981 gatccaaacc agtcaagggt tcgtccaaga cccaaatatc aggatcagac aagagtgccc
     2041 cgatgacaaa aactttctga cgcattccat gagaaagggt ttcaataacc tgataacgat
     2101 tttcagcaaa atcaaaaacg ttcaatagcc tagctagact agtctccaag tcagagctag
     2161 tcagatcata ggatgaggcg atcaattccc aaaattcatt ggccgttaaa cgtaaaaata
     2221 agtcaggcga gtctgctacg tagccaatct ttcgtttgat cgccaagcga ttttccgata
     2281 actcctgacc atctaccaaa atacgaccac tgctgggtga aatgatactg actagggatt
     2341 ttatggtggt cgattttcca gccccattat gaccaatcaa gcccataatc tctccatttt
     2401 caatctgcaa attgagatta ctcaaggcct ctttatcacc atacaactta ctaacatttt
     2461 gaaattcaat catgggatga ctcctatctt tatctgtatt atacatcgct atactagcac
     2521 tttgatacaa aaaaatcaat actttatttt aagtagttaa aatagtttcc ttctatctta
     2581 cgcaaacgtt tgctccgaga gatactttat gatagaataa agaacaagat tgacaagtaa
     2641 gaggaaacat catgcaaaat caaacactca tgcaatactt tgaatggtat ctgccccacg
     2701 acggtcaaca ctggacgcgt ctggctgaaa atgctccaca cctagctcat ctggggatca
     2761 gtcacgtctg gatgccacca gccttcaagg caaccaacga aaaagatgtc ggctatgggg
     2821 tctatgactt atttgactta ggagagttca accaaaaagg gactgtccgc accaagtatg
     2881 gtttcaaaga agactatctt caagccattc aagcccttaa agcgcaggga attcaaccta
     2941 tggccgatgt agttctcaac cacaaggctg ctgctgatca cagggaagcc tttcaggtta
     3001 ttgaagtgga tcctgtagac cgtacagttg aacttggaga acccttcacc atcaatggct
     3061 ggactagttt taccttcgat ggtcgccaag atacctacaa tgacttccac tggcactggt
     3121 accacttcac aggtacagac tatgatgcca aacgccgtaa atccgggatt tacctaatcc
     3181 aaggagacaa caagggctgg gctaacgagg aattggtcga taacgaaaac ggaaactacg
     3241 actacctcat gtatgccgac ctagacttta aacatcctga agtcatccaa aacatctatg
     3301 actgggctga ttggttcatg gaaacgactg gtgtagctgg tttccgtttg gatgccgtta
     3361 agcatattga ctctttcttt atgcgcaatt tcatccgcga tatgaaggaa aaatacggtg
     3421 acgatttcta tgtttttggt gaattttgga acccagacaa ggaagccaat ctggactatc
     3481 tcgaaaaaac ggaagaacac tttgaccttg tcgatgttcg tctccaccag aatctctttg
     3541 aagccagtca agctggcgca aactatgacc ttcgtggcat tttcacagat agcctggttg
     3601 aactcaagcc tgacaaggct gtgacttttg tcgacaacca cgatacccaa cgaggacaag
     3661 cccttgagtc taccgttgaa gaatggttca agccagcagc ctatgccctc attttgttac
     3721 gccaagacgg ccttccatgt gtcttttacg gagactacta tgggatttca ggccagtatg
     3781 ctcaagaaga tttcaaagaa atccttgacc gcctcctagc catccgaaaa gacttggcct
     3841 atggagaaca aaatgactac tttgaccatg ctaactgtat cggttgggta cgttcaggtg
     3901 ctgaaaatca atccccaatc gcagtcctta tctcaaatga ccaagaaaac agcaagtcaa
     3961 tgtttgtcgg tcaagaatgg actaatcaaa cctttgtaga tttacttggt aaccaccaag
     4021 gtcaagttac aattgatgag gaaggttatg gacaattccc tgtctcagct agatccgtaa
     4081 gtgtctgggc agtcaatacc atctaatagc tcataataac caagctaggt ccaagcggat
     4141 ttggcttttt tgtattcaca aaaagaccta cccaaatgga tagatcttta cttgattaca
     4201 atttacctgc tactgcatcc aacaattctt ggatcttagc ttggttgctt cctcctgcca
     4261 tggccatgtc tggtttacca ccaccacgtc catcgatgat tggtgctaat tctttgacaa
     4321 ggtttcctgc atgaaggtct tttgtcttgc ttgctacaag gacattgact ttgtcaccga
     4381 tagcggcaac taggacaaga agatcagagt agtctttttg tttccagtta tctgcaaaag
     4441 tacgaagggc accggcatcg gatacagaca cttgactagc aatgtaacga tgaccgttga
     4501 cttccttaac atctttgaag atatcgcctg cggctgcagc tgcggctttt tctttcaact
     4561 cagcattttc tttttgaagt tgacgaagtt gttcttgaag tccttctacc ttgtgaggta
     4621 cttccttgac ttgaggtgct ttcaaggttg ctgcgacagc tttaagagca tcctcttgtt
     4681 cacgataggc ttcaaaggct tccttaccag tcactgccaa gatacggcga gttcctgaac
     4741 cgattccttc ttctttgaca attttgaaga gaccaatctc agaagtgttg ccaacatgag
     4801 taccaccaca aagttcaata gagtagtcac cgatagtcac gacacgaact tccttgccgt
     4861 atttctcacc aaagagggcc atagctccca tttctttagc agtgtcaata tccgtttcaa
     4921 ctgtcttcac ttcaagtgct tcccaaattt tctcgttaac ttgctgttca atcgcacgaa
     4981 gttcctcagc agttactgct tggaagtggg taaagtcaaa gcgaaggaat tcaacttcgt
     5041 taagagatcc tgcctgtgtt gcgtggtttc caaggatatt gtgaagggca gcgtgaagca
     5101 aatgagtcgc agtgtggttt ttcatgacac ggtgacggcg attgctatca attgccaagg
     5161 tatattcttg gttcaaggca agcggtgcaa ggacttcaac tgtatgaagg gcttgaccat
     5221 ttggggcttt ctgaacattg gtcacagtag ccacaacctt acctgactca tccaagattt
     5281 gtccgtagtc agctacctgt ccacccattt cagcataaaa tgacgtttcc gcaaagataa
     5341 gagaggcagt tccttctgaa acagctccta cttctgcatt gtcagcaacg atagctacca
     5401 atttagaaga caattggcta gcattgtagt tgaagacact ttctacagtg atgttttgaa
     5461 gagtttcatt ttgcataccc attgagccac ccttgacagc tgacgcacgc gcgcgttctt
     5521 gctgttcttt catggctgct tcaaaacctt cacggtctac agtcatacca gcttcttcag
     5581 caatttcttc agtcaattca actgggaatc cgtatgtatc atagagttta aagacatctt
     5641 gaccagcaat gacagattga cctttttctt tcaagtctgc cacaatgcct tgggcaaagt
     5701 gttgacctga gtgaagggta cgggcaaatg attcttcttc gctcttaacg attttctcaa
     5761 taaagtcacg tttctcaagc acttctgggt agtagctttc catgattttt ccaacagttg
     5821 gcacaagttt gtaaaggaaa ggctcgttga tacccaattt ttgaccatgc atagaagcac
     5881 gacggagaag acgacgaaga acataaccac gaccttcatt tcctggaagg gcaccatcac
     5941 cgatagcaaa tgaaagagaa cgaatgtggt ctgcgataac cttgaagctc atgttgtcgc
     6001 catcttggtc ataaacctta ccagacaatt tctcgacttc acggataatc ggcataaaga
     6061 ggtccgtttc aaagttggtc ttagcccctt ggataacagc caccaaacgc tccaaaccag
     6121 cgcccgtatc aatgttctta tgtggcaatt ccttgtattc gctacgagga acagcagggt
     6181 ctgcgttaaa ttgtgacaaa acgatgttcc agatttcaat ataacggtcg ttttcaatat
     6241 cttctgcaag caggcgaaga ccgatatttt ctgggtcaaa ggcttcccca cggtcaaaga
     6301 agatttctgt atctggtcca gaaggtcccg caccgatttc ccagaagttg tcctcaattg
     6361 gaatcaagtg acttggatcc actcccactt caatccagcg gttgtaagaa tctttatcgt
     6421 ctggatagta ggtcatgtaa agtttttcag cagggaaatc aaaccattca gggcttgtca
     6481 aaagctcata agcccaagtg atagcttcgt cacggaagta atccccgata gagaagttcc
     6541 ccaacatttc aaacatggta tggtgacgcg cagtcttccc tacgttttcg atgtcgttgg
     6601 tacggatagc cttttgggca ttggtaatac gtggattttc agggataatg gtcccgtcaa
     6661 agtatttctt aagggttgct accccagagt tgatccacaa aagagttggg tcatttacag
     6721 gaaccaaact tactgatggt tctactgagt gacctttggt cgcccagaaa tcaagccaca
     6781 tttggcgtac ttgtgcacta gatagttgtt tcatattgtc tccttattca cttgtttaat
     6841 gtgattggct ttccagcatt tccacatagt caatcgcgac acagagggaa atgactaggt
     6901 ctgcataagc gtcttcaaga accgttacgg tataggtaga ggtcagatgg aagagttcct
     6961 tcttaatttc cgcaatcaac tgatcgcgat catccagcaa ttggaaattc aaatcccaga
     7021 tattgccctc gatacgaaga cctagattat caaactcata cttatctcgc cagaaggtca
     7081 acttcttacg aatgacaaaa ctcgagccat cccgaagctg aatctcaaaa cgaggaagca
     7141 aggtcaagat ttctttactg atctgactga cttgttcacc agccgcatca tagatggtaa
     7201 aagttttggg aatcttaaaa aatgatccct ccacctgata ggcaatttct cccctgtcat
     7261 ccttgatagc gaagcgttcg cctccaagac gaaacttttg tttgacaaga aatgttttca
     7321 tcaacacctc caaaaatcaa aagacaagct catatcacga agggcgaaaa accgcggtac
     7381 caccttcatt caatgaactt gtcattctct tgttcttatg caattgtatg attgagtagc
     7441 atgacttcct agcttagatg gctcgcagca ccgccatttc tctggactaa gacaagtgaa
     7501 aatcaattct caactttctt attataacgt ttttttaagc ttgcgtcaac tggaaatgat
     7561 ctccgttgaa ttagaccaat tccctacatc tctgattact ttttcaggat atattttttc
     7621 ttactgccat ttttcttttt atcccaaatt ttcatattac taaacacagc tactagaata
     7681 tttccaaata taaaggtgcc tatcacccaa tatatggact cagttgttag gtattgtcga
     7741 tccaagccat cctttaaatg gaatagtata gcagtttggt taacaatcat aaaggttggc
     7801 cagaaacttt ttttgaaaaa agtagacatt ttcattattt gttgccgctt tctgtaaggt
     7861 taatactcaa taaaaatcaa aaagcaaact aggaagctag cctcaagctg tacttgagta
     7921 cggcaaggca acgctgacgt ggtttgaaga gtataggctt agtatactac taggcaagca
     7981 aataagcaaa taaacaacta gaatagaaaa agatagggct ctaaaaactg acttctattc
     8041 cttaaaaaca aaccagcttg actgattcgt cttcttacgt ttatctccta cttccgatac
     8101 attttaaact gtaggaagag gtcgctatat ttccctgtcc atttatggtc aaatttctca
     8161 taaacttcta ggtgtttcat ggtttcaaca tcgggataga aggccttatc ttcctttgtt
     8221 tcctctggga gcaattcctt cgctggtagg tttggtgttg aatagccgac atactccgca
     8281 ttttggagag cattttcagg tttcaacata aagttgataa aggcataggc tgagttttgg
     8341 tttttaactg ttttgggaat gaccatattg tcaaaccaaa gattgctggc ctctgtcggt
     8401 accacataac gtagattttc atttttttct aacatttggc tggcttcacc agagaaggtc
     8461 acgccgattg caacattatt ctgaatcata tagcccttca tctcgtccgc aacgatagcc
     8521 ttgatatttg gagtcagttt gtagagctta tccactgtct cttccaactg ctgcagatcc
     8581 ttggagttga ggctgtagcc gagggaattg agtcctagtc ccagcacctc acgcgcccca
     8641 tcaaagagca tgatagaatt cttatactcc ggcttccaaa ggtcatccca atgctcaggc
     8701 gcttcatcta ccatggtttc gttgtagaca attcctaagg ttccccagaa gtaagggatg
     8761 gagaatttat tacctgggtc aaaggactgg ttgagaaact ctggtccgat attttcgatt
     8821 ccttcaattt ttgaataatc aagcggaacc aagaggtctt cgtccttcat cttgttaatc
     8881 atgtattcac ttggaatggc aatatcgtag gtcgttccac cctgctttat cttagtgtac
     8941 atggcttcgt tggagtcaaa agtctcgtac tgaacttgaa ttcctgtttc ttctgtaaac
     9001 tgagtcaaga gttcaggatc gatatagtct ccccagttat agataaccaa tttttgacta
     9061 tctcgactat tgattttact atctaaatga gtcgcaattc cccacaagac aaggataatc
     9121 gctgcaattc ctgctaaaaa tgaatagatt tttttcatgc ttgctcctcc ttctcacgag
     9181 agataaagta ataacctaca actaggataa tactaaagag aaagactaga gcagacaggg
     9241 cattgatttc taaggaaatc cccttgcgag cacgagagta aatctcgact gatagggttg
     9301 aaaagccatt tcctgttaca aagaaggtca cggcaaaatc atccagcgaa taggtgaagg
     9361 ccatgaagta acctgcaatg atagacggag tcaggtaagg aagcatgatt tccttgaaca
     9421 tctgaaattg actagctccc aagtcatagg ccgcatgaat catgtcgcca ttcatttcct
     9481 tgagtcgagg caagaccatc aagaccacga taggaatgga gaaggccacg tgactagata
     9541 gaacggtcaa aaagccaagt gaaaacttga gttgggtaaa gagaatcaag aagctagcac
     9601 caatcataac gtcaggcgca accatgagga tattattgag tgatagaaag gcttcttggt
     9661 atttcttacg agactggtag atgtaaatgg caccaaaagt cccgataatg gtcgctatca
     9721 aggctgatag gaaggccaag aaaaaggtct gagccaaaat cagcatgagt ctcccatctc
     9781 caaacatggt ttcaaagtga gtccagctaa aacctgtaaa gctattcata tcatcaccag
     9841 cattaaaggc atagccaatc aagtaaaaga taggcaggta gaggaccaga aagaccagtc
     9901 ccagataaag gttggcaaat tttttcatcg ttctctcctt tccttagtca cccacatggt
     9961 gatgaacatg gtcaggatga gaatcacacc gatggttgaa cccataccat agttgtcatt
    10021 ggttagaaaa ttctgctcaa tagccgtccc caaggtgata acgcggttcc caccaatcaa
    10081 acgggtcagc atgaagagac tcaaacttgg gataaagacc gactgaaccc cacttcgcac
    10141 accgttcata gatagaggga agatgacatg acggaaggtc tcccacttag ttgcaccaag
    10201 gtcatagctg gcattgatga gattattatc catatcgtct aagacattga aaatcggcaa
    10261 aatcataaag gggagctcga tgtagcttgc gacaaagata aaggaaaaat cggtaaaaag
    10321 caactgttgt gaaccaattc cgataaattc caagaattgg ttaatagagc cattttgacc
    10381 aaaaatcccg ataaaagcat aggctttaag gagcaaattg atccaggtag gaaggataat
    10441 cagcatgagc cagagttgac ggtgcttgag acgggtcaaa aagagggctg ttggatagct
    10501 gataagcaag gtcacaaagg tcacaatccc tgcataaagc actgagttga aactcatttt
    10561 gaggtaggtc aagttttgtg acgcaaagta agatttataa ttttctaaac taaactggcc
    10621 ttcaatgttg aaaaaggatt gtccgaaaat caagaccaag ggtgccaata caaagagggc
    10681 aatccaaagc atgtagggca ctacaaagag tttagagctt gttttcttca tctctttcct
    10741 cctcgatcgc attgatcaga cctgcttctt gctcttcgat ttccacgtat tcttcgatac
    10801 gagcatcgaa ctcttcttcg gtttcattga gacgcatgat gtggatgtct tctggttcaa
    10861 agtccagacc gatttcctca cccacgatgg ccttacgggt tgagtggatc atccattcat
    10921 ttccaagttc gtcataggcg ataatttcat aatgaactcc acggaagagc tgggtgtcga
    10981 ccttaacttg gagtttgcct tcttcaggaa gggtaatgcg caagtcctct ggacgaataa
    11041 cgacctcaac aggttcattt ggcttcatcc caccatcaac cgcttcaaag cgtttgccgt
    11101 taaattcgac caagtagtcc tcaatcatgg tacctggcaa gatgtttgac tccccgataa
    11161 aagtggcaac aaagtggttg attggctcat cgtagatgtc cacaggggtt ccagactgga
    11221 caatctcgcc atcattcata acgaaaatcc agtcactcat ggcaagagct tcttcctgat
    11281 cgtgagtgac aaagacaaag gtaatgccca atcgttgttg taattcacgc aattcgtact
    11341 gcatgtctgt tctcaatttc aagtccagcg ctgataaagg ctcgtccaac aagaccacac
    11401 ggggttggtt gatgatagca cgggcgatgg ccacacgctg acgttgtcct ccagaaagtt
    11461 tgcggatgga acgtttttca taaccttcca actgaaccat cttgagaact tccgctacac
    11521 gctgctcaat ttctttctta tcaattttac gcaagcgaag tggaaaggca acattttcaa
    11581 acacattcat atgtgggaac aaggcatagg attggaagac ggtatgtacg tcgcgcttgt
    11641 tggttggaat atcattgata cgaacaccgt ctagcatgat atctcctgtc gtcgcatcca
    11701 gtaaacctgc aataatgttt aggatagttg atttccccga accagatgca cctagaaggg
    11761 tgtagaattt cccttcttcc aactcaaagt tgatgtcttt gagaaccttg gtgttgctgt
    11821 cttcaaaaac tttagagacg tttttgaatt cgataattgg ttttttcaat tggcataaat
    11881 tccttctttt tcatagatta accgatcggg gctctgtcag gtccccacta cctcttgcag
    11941 ggagtaaaac cacctgcata catcttcgct accgataggc tttcaccccc tttccatgac
    12001 atagcagcag cttttcaaat acagcttcct acttgctttc acccaagatc cggacttctc
    12061 tttcaagcgt aatacctgag tgttccttga ctttttcgat aaccgattgg atcaagtcct
    12121 cgtagtcttt ggccgttcca tctgcgacat tgatcataaa tcctgcatgc ttttctgaca
    12181 cttctacgcc accgatacga tagcctttca agccagcttc tgaaattaac tgacctgcaa
    12241 aatacccgac tggacgctta aagaccgagc cacaagatgg gtattccaaa ggttgcttga
    12301 gttcacgtaa gtgcgtcaag cggtccattt cctgcttgat aacctgatgg gttcctgggg
    12361 ctagggcaaa tttaactgac aagacaactg caccagactc ctgaatagct gaatggcggt
    12421 aaccaaaagc caagtcttta gcagacaggg tttcgatttc tccatccttg gtcaagacct
    12481 tacaagactg caagatgtga gcaatctcgc caccataggc acccgcattc ataaagacag
    12541 caccgccaac gcttcctgga ataccacaag caaactcaaa gccagtcaaa ctatgacgga
    12601 gggcaatgcg agttgtttca atcaagttag ccccagcttc tgcttcaatg gtatagccat
    12661 caacagaaac gttattgagc ttgtcacaca agatgacaaa tccacgaatc ccaccatcac
    12721 gaacgatgat attgcttgca ttgccaagaa ccatccaagg gatattttct tggttggcaa
    12781 atttcacaag gcgcgccaac tcaaaacgat ttcgtggaaa gaccaaataa tcagcctctc
    12841 cacctacttt tgtataacta tagctatgca agggttcctt aaaacggata tcaattcctt
    12901 ctaagatttc aagcattttt tctcttacag acatgtcact cttcctttta caaaattcat
    12961 tccattatac catttttaga gacatttgac gaccataaaa ataccttgtt tggattttgc
    13021 ataagaaaaa gaggttcccc cctttttatg attttttaca aaagatttcc ttggttccat
    13081 aggcgaccag aacgagctcc agtgctagaa tcacttcaac caagactgga tttgtcaacc
    13141 agcctacttg gaaaagagat ggtgccagat caaaaaaggc atgcaagcca taggctgcta
    13201 ggagataaat ccatttcttc tggcgaacag cttggtaaac ccaaactgtc aaaagtaatt
    13261 ggaaaccaag cgccaagatt cgctcaaaac caagcaaata aatctgccag accgaaagtg
    13321 actgaatggt ttttaacata ttttcagaca gtaattgcat aacctgtgct gtggattctg
    13381 agtttgaact gccgaaagaa cgatgtaaag attgagtaaa ctagtaaggc ctagaaaaat
    13441 caactccaag ccaccatgcc ctaggccata ggccaaggca tctgcctttt ccaaacttct
    13501 ctttttctcc aaccatttga agaaaacaag acgagccgtt tcctcaaaaa atgctgccat
    13561 ggctaggcca tagataatat agataagcgg atgatcttgc aagagggcaa tactaccgtc
    13621 tttttgaggg tgcaaaatca agatatgcac cagtttttcc aaaatctgcg aagagacaaa
    13681 gaaagcgact gcacccaagc ccaagacagc tagattaatc tggtatttct ttttggcaaa
    13741 ccaaatgctt cctatcagaa aagctagcaa cagcaacatg gtaataatga tatgaatggt
    13801 cattttcttc tcctattctg ccttttcaat atcttttttc atctcgtcaa cattgaactt
    13861 agcaaacaag tattgacggt cttggactgg gaaacgttgg tccaactggt caactgctcc
    13921 cacctcgata atgccttcct tgatgacaaa atccatgaca tgtccaccga aggtcaaatc
    13981 atctgatatg aagtgcagat ggtagcctgc cacactgacc ccatggaaaa tctcaggcgt
    14041 ccagaaacca acaatagtcc ccgcaacatt gtcacgacta tattccggtt gatgggttgc
    14101 gacatcagca aacttggtat cgggtgttga cttaggaatc atacgcacat gcatatgtaa
    14161 aaattccccc cgaatcttga tagagcggaa aagattttcc ccatcataat aagactcaat
    14221 tcgttctttc aattccttgt ctgtcatctc aaagcgctgg cggaaaatga cctctgcctg
    14281 atgcggtacc actgcagcgt aaggaataag ggcatctggt gacacttcca caatttctgg
    14341 ctggtctcct gaccctttgg cctgataagc cttgccatcc aagacaatca attccccatc
    14401 aatggaatcc aaggttccca aaccaaggtc accatgttct agcaattctc ctactgtcat
    14461 agtaccacca taaaggccag ccatcaaggc tccaagagta ttgtattgaa ataatttcac
    14521 tggttcctgc acgttcttat ccattcactt tcttgtctgt tattctataa atcttactcc
    14581 taagtatacc acatttgccc ctagatgtga acgagagaaa cgctctagac attgccaaga
    14641 aggaaaaaaa agggtacaat gtaacaaaat caagggaggt ctggaatgaa gaaacaaagc
    14701 aagtacaaag aggtcgtttc ctatctgaaa aatggtatcg agtctgaacg atttccgacg
    14761 ggtagtcgcc tgccttctat ccgtcaactg agccttgact ttcactgcag caaggacacc
    14821 attcaacgag ccctgctgga attacggcac gaacaatacc tctatgccaa gcctcagagt
    14881 ggctactatg tattagaaca agggcaacat caagacctag aaatcgaggt taccgacgaa
    14941 catgccagtg cctatgacga tttccgactc tgtgtcaatg aaaccttgat tggacgagaa
    15001 aactacctct tcaactacta tgacaatcaa gaaggattag aagacctaag acagtccatt
    15061 cacaaactcc tatttgagca agctctctac tgcaaggcta accaactagt actgacttct
    15121 ggaacccaac aagccttgtt tatcctctct caaatatcct ttcctagaca agccaaggaa
    15181 atcttggtgg aacagccaac ctaccatcgg atgaatcgcc tcttgattgc acaggggctg
    15241 gactatcaaa cgattgaacg aggcattgat gggattgact tggaggagct ggaaggccac
    15301 ttcaaaacag gaaaaattaa atttttctac accattccta gatttcacta tcctctggga
    15361 cattcctatt ctgagcaaga caaacgatct attcttaact tagctgccaa gtatgatgtc
    15421 tatatcgtag aggacgatta tctgggtgat ttggactcca agaagggcca aaccttccac
    15481 tatcttgata cagaggagca tgtcatttat atcaagtcct tctcgaccag cctttttcct
    15541 gcccttcgta ttacagcact cattcttcca aatgctatca aagaagcatt tgtggcctac
    15601 aaaaatatcc tagactacga cagcaacctc attatgcaaa aggccctgtc actctatatt
    15661 gacagtcaat tgtttgaaaa aaatcgtttg gctcgcttga ccaatcatga atcttaccaa
    15721 aaacaaatcg aggaaaggat aactaaaaca ccttgtcccc ttcctcatta tcccctacac
    15781 gatggtttat tgctagacct gagacagtat cctaaaatcg ccagtctcaa acacagtcaa
    15841 ctgggcttgg acttctttga agaggcctat ttaagcacct gtccttatca atttgccaag
    15901 gtgtccctag acaatctgga aaatgtttta aactatttaa aagcagaatt ggaatgacat
    15961 ccaactctgc tttttcttat tcttcaactt cagttagact tgctgctttt tcaagatagc
    16021 tttggtaagt tccttcatcc ttaagttttt ggatgacctt gtctaccact tctttcaaat
    16081 catcactatt ttttctaaga gcaacggcat tggcgtcgcc gtccttcatc ttcaagctga
    16141 cagttgcgac agctaagcca gcgtttttag cagcataact aagtgcaaca ggctcatcca
    16201 tatgaacagc atctattttt ccagcctgca attcattgac tgcttcaccc atattagtta
    16261 gggaagttaa ttgaactttt ggcaattgtt ccttgaccat tgattctgga acagtccctt
    16321 tttgggctgc aatattagca ctttctaggt tagttaaatc cttgtatttt tccacatcag
    16381 ccttacgaac caagaaacta atcttgtttt catagtatgg gattgaaaaa tcaaagactt
    16441 cttttctctc gtcagtagca ctaattcctg caactgctag gtcagcctta ccagtttgaa
    16501 gactggtcaa aacattatca aaactcatgc ttgagatttc caacttaacc ccaagttcat
    16561 cagcgatagc ctgagccatg tcgatgtctg caccgactac ctggttcttt ccatcaacca
    16621 atgattgaaa ttcaaagggt gcatagtcag gactggttgc cacaactaat ttcccctttt
    16681 gcttaatggc ctcaacagct gactgagaac cattagaacc tgactggcaa gctactaaga
    16741 agaaacttgc aagaaaatta cataaaacaa atatccattt ttttgatttc ataaataaac
    16801 aacctctctg ttaattttgt ataattataa cgatatccaa gttacttgtc aagtgttttt
    16861 taaattttta tctcaaaaat attttttcgt tcaaaaaaag gagccatcag ttgatttcaa
    16921 gctccttttt atacagaatt aaactatttt atagttcgac aatcttacct gtttcaaagt
    16981 agacaaccca ttcacagata tttttagcat agtcaccgat acgctccaag taggaaataa
    17041 cttggaaata atcacgaccc gtaacaatgg cttctggatt tttcttaatc tcttcagtcg
    17101 caaggtcacg gatagtttca aaatagtggt taatttgctc atccatggag gccacccggt
    17161 atgcgtcgtc aacagaacca ttaagataaa gatcaagtgc tgcttcaaca acgcttttaa
    17221 cttcacgtcc cattttttta atttcttcct ctacagctgg aatgcgctct tcccccttca
    17281 tacggatggt tgcctgagca atggctacag cgtgatcccc catacgctcc acatctgata
    17341 cagccttaag gacagtcaag actgtacgca aatcttgaga gactggttgt tggagtgcga
    17401 tcatttcaaa tgatttcttt tccagtttca cttcgtattc atttacttct gcatcatctt
    17461 cgatgacctc ttttgccagg tcacggtcat gcgtgacaaa agcacgtacc gtacgattga
    17521 tttgtgagag cacttcttgt cccatagcgt agaactggtt atgtaatttc tctaaatctt
    17581 cttcaaattg agatcgtaac atctttcatc tccttatcca aattttcctg taatatagtc
    17641 ttccgtttcc ttgtgttggg gattaaggaa catctgcttg gtatcattaa attcaatcaa
    17701 atctccatct aggaaaaatc ctgtcttatc agagatacgt gaagcttgct gcatggaacg
    17761 ggttaccaga agcatggtgt acttgtcttt tagaccatac aaggtttcct caattttacc
    17821 agctgaaatc ggatccaaag ccgaagttgg ctcatccaag aggatgattt taggactagt
    17881 tgccaagaca cgggccacgc agacacgctg ctgttgacca cctgacaatc caatagctga
    17941 atcatataga cgatccttga cctcatccca gatagaggca ccttgcaagg ctttttctac
    18001 ggcttcatcc agaacctgct tatccttaat tccattgata cgaagcccgt agacaacatt
    18061 ctcatagata gtcataggga aaggattagg ttgttggaaa accattccga tttccttacg
    18121 taattcaacc gtatctgtac gcggactgta gatgttgtga ccattgtaca ccacggatcc
    18181 agttgtggtc acctctggat tgagatctcc catgcggttg agagacttga ggagggttga
    18241 cttccctgat ccagatggac caatcaaggc tgtaatttcc ttaggttgga aagataggga
    18301 aacactattc aaagccttct ttttattata ataaacggac aggtctgata cctgtaaaat
    18361 cgcatctgtc atacggtttc ctttctaacc aaagtgacca gatacatagt cattggtgga
    18421 ctgtagcttg gcattttgga aaatagttgc agtcttgcca tactcaatca aatcacccaa
    18481 gtaaaagaag cctgtatagt cacttgcacg agcagcctgc tgcatattat gcgttacaat
    18541 gatgatggta aagtttttct tgagctcaaa catggtctct tctagttgca tggtcgcaat
    18601 cggatccaag gctgaggctg gctcatccat taagaggata tctggcttaa cagagatggc
    18661 acgagcgata cagagacgtt gttgctgacc acctgataag gtcaaggctg acttgtggag
    18721 atcgtcttta acctgatccc aaagggcagc ctgacgaagg gaggtttcta cgatttcatc
    18781 taggacttgc ttatccttaa ctccagcacg ttcatgcgca aaggtaatat tacggtaaat
    18841 tgacttagca aatggattgg ggcgttgaaa aaccattcca atgtgtttac gcatttcata
    18901 aacgttgatt tctggacggt tgacatcaat tccacgatag agaatctgcc cagttacttt
    18961 agcaatatca atggtatcat tcatgcgatt gagactgcgt aagtaggtag atttccccga
    19021 tcccgacgga ccaatcaaag ctgtaatttt atttctttca aattgcatat caatcccctt
    19081 aatggattca tttttaccat agtaaacatg gacatcctta gtagaaaggg ctactttttc
    19141 ttcaggaaag gtaaggatat gcttctcatc ccagttatat gttgacatgg cttctccttt
    19201 aggcagcggt taatttcttg tgtagatagc ttccgaactt acgagctcca aagttaaaaa
    19261 tcaggataaa gatcaggagc acagcggcag aacctgctga tacaatggtt ccatctggaa
    19321 tagtgccttc actattgact ttccagatat ggacagccaa ggtttctgct tgacggaaga
    19381 tagagatggg gctagtcaca ctgaggatat tccagttaga ccagtcaaga gctggcgccg
    19441 attgccctgc tgtatagatc agagctgcag cttcgccaaa gatacgacca gatgccaaaa
    19501 cgacacccgt tacaatacct ggaagcgctt ctggaataac aacatgaacc actgtctccc
    19561 agcgagaaat cccaagagcc agaccagcct cacgttgggt atggtgaacg tgtttcaaac
    19621 tatcctctac attacgcgtc atctgaggca agttaaagac tgtcaaggcc aaggcacctg
    19681 aaatgattga aaatccatac tcaaactgga ctacaaagat caagtaacca aagagaccca
    19741 ccaccactga tggtaaagag gacaagattt caatacaagt ccgcacaaag ttggtaacag
    19801 gacctttttt agcatattca gccaagtaaa tcccagctcc catagaaaga ggtacagaaa
    19861 taatcaaggt aatgaccaat aggaaaaagg aattgtaaag ctgaatgcca atcccaccac
    19921 ctgcttgaaa agcagaagac cttccagtca agaaagacca agagatatgg ggcaagcccc
    19981 gaaccaagat atagagaatc aaggaagcca agattgtcac aatgatgcta gcaatcgtat
    20041 agaggacagc tgttgcaagt ttatctaatt tcttagcgcg cataattttt ctttcctctt
    20101 tctttcgtaa tcaatttaat cacactgtta aaaactaaac tcatcaagag cagtaccaag
    20161 gccagtgacc agagaacatt attatttaca gttcccatga cagtgttccc aattcccata
    20221 gttaatatag aagttaaagt tgcagctggt gtggtcaagg aagttgggat aacagctgag
    20281 tttccgacaa ccatctggat agctagagcc tcaccaaagg cacgcgccat cccaaagacc
    20341 actgcagtga aaataccaga acgggccgcc ttcaagatca cacgccagat agtctgccag
    20401 cgagtggctc ccatagcgaa actggcttca cgataataac gaggaaccgc acgcaagcta
    20461 tccgttgtca taaaggttac ggtcggcaaa atcatgacaa agaggacgga aatccctgac
    20521 aaaatcccaa aaccagtccc accaaagaca ctgcgaacaa agggaacgac gacttgcaag
    20581 ccaataaatc cgtacactac tgaaggaatc ccaaccagga gttcaatagc tggttgcaaa
    20641 atcttcgccc cttttggtga tacttcggtc ataaaaactg ctgcaccaat agcaaagggt
    20701 gttgcgataa gggctgagag aatggtaacg ataaaggaac ccaaaatcat aggaagggca
    20761 ccaaattctt tactagaagg attccaagtt cctcccaaaa gaaagtcaaa gatattcaca
    20821 ccattgacaa agaaggtcga caagcctttt tgcgctacga aaaccaaaat catggccaca
    20881 aggatgacta tcaaagaaag acaggcaaag gtcaaacctt ttcctaattt ctccagacga
    20941 gaattctttg atggaagcaa cattttcttg gctaattctt cttgattcat tattgtctcc
    21001 cttccaacac tgtcacagtt ccggcagcat ctttttcaac cttcatttcc ttaatcggaa
    21061 tatacttcaa tcctttgaca atcccttctt gggtctcatc cgagagaaca aaattgagaa
    21121 attctgcagc caactcattg ggctgcccca atgtatacat atgctcataa gaccacaagg
    21181 gccaattatt gctacttata ttttctggac ttaagtcata gccattcaac ttcatgcttt
    21241 tgaccgaatc atctatatag gtaagagata aataagagat agctcctgga ctttttgata
    21301 cgattgattt taccgctcca tttgaatcct gctcctgact ttgcatggca gactgacctt
    21361 ccataatgac agtatcaaag gtagcacgag agccagagcc ggctgcccga ttgataacag
    21421 agatgggtaa gtccttacca ccaacctctt tccaattggt tacctcacct atgaagattt
    21481 gacgaagttg ctctgtcgtt aggttatcaa catcaacctc cttattgaca atcagagcca
    21541 agccagctac cgcgaccttg tggtcaacaa gagcagaagc atcaattccg tctttttcct
    21601 cagcaaatac atctgagttt cctatatcaa ctgccccaga ctgaacctgg gacaagcctg
    21661 taccagaacc tcccccttgg acattgaccg tttttccaac atggatcgtg ccaaattcat
    21721 ctgccgctac ttcaaccaag ggttgcaagg cagttgagcc aacagccgtt atggattctc
    21781 cacgatcaat ccagctagca cagcctacta aacaagccgt cagccaaaaa gcgataagag
    21841 acagagcaag cttttttctt tttttcactg tttttctcct cgaaaataat tatgaatact
    21901 gtgaattttt taagtagttc tttatgagtt gacgcatgaa ttcttaccaa atttctgcgc
    21961 aattgattat ttatataata taggctatat tactctttcc taacctcctt ttttcatatg
    22021 tggataaaat ctcttgtcta tcccttcccc cattgtcacc cattatagtc atttcgtgtc
    22081 tctttttccc ctttttaatg caagggaaat tactcttctt agatgataat ccaaaagcta
    22141 gaaaggtatc tcaaacctct ctactctccc agactagttt acaactaaaa ggaaaagatt
    22201 ctattttatg agaaatctag tttacaagcg gtaagaacgc taataactaa acttcttgta
    22261 ctctttgaaa atctcttcaa accagtgttt tgagctatct atggctagct tcctagtttg
    22321 ctctttgatt ttcattgagt agtaaaacta catgtaatgg caatcaagat atcaagaatc
    22381 atcctactaa aaaaatccat actttcacta taacatagaa taagatattt gactagcatt
    22441 ttcatttgaa tctgaggcct tttggaaaat aatttttcaa aacatttcca gtaacctttg
    22501 caaagcccaa gccattgcct ttaaccaaaa cttggtacca accatttggc agactttctg
    22561 ccagctgaac gatttctcca gccgcatact tgacaaacgc ttcttggcca atttcaaccg
    22621 actgttcgac ctgactcggt ttcaaggcta aaccaagagc gaaactgggc tcaaagcgtt
    22681 tcttcttaaa agtgcccaga tgcagtccat tgcgagcaat cttgagcttc cctaaatctg
    22741 gcaaaagttc tggcaagaga taaagctggt ctccaaaagt ctgcaagata cccggtagat
    22801 tgaccttcaa atggttttgg gcaaattcct gccacaaggc aacttgttca cggctgaggt
    22861 tactcttact tgccttaaat ttaggagctg gattgttacc cttaaactgt agatgggcaa
    22921 caaactgacc ctctccctta aactgatgag gatacatccg agccgtttct ggcaggtcaa
    22981 taccagctac cattccattg atatgctcta ctggcaacaa gtcaaaatca tactcttcca
    23041 gcaaccaatt gacaatctct tcgttttcct cgggtgccca ggtacaggtc gaataaacca
    23101 gacgaccacc ttcagctaac atggtcactg catcctccag aatttctctt tgcaagctag
    23161 cacattgact cggataatct aagctccaat agtccatagc atcaggttgc ttacgaaaca
    23221 ttccttcacc agagcaaggg gcatcaagaa cgattaagtc aaaatagcct ttaaagacct
    23281 tgaccaagcg gtcggcagat tcattggtca ccacgacatt tgtcgctcca aaacgctcca
    23341 tgttttcaac caaaatctta gcccgtttgc ttgaaatttc attggaaaca agtagcccct
    23401 cccctgctag ataggctgcc agttgagttg atttgccccc cggtgcagca gccaagtcca
    23461 agaccttcat accaggactg ggttgggcta cttgagccac catttgagca gcaggttctt
    23521 gcgaataaac taaacctgta gcatgctcag gcgatttccc tgaaaccttc ccatagtggc
    23581 cccaaggggt ttgagtaatg gcatcagaaa aggaaagttg ctcttctttt aagggattga
    23641 cccgaaaggc cgaaaccgct tcctcctcaa aagaggcaag aaaatctctt gcctcatctc
    23701 ctagtatttc tttatatttt tcaacaaatc cttctggaaa tttcatttaa gttcttttcc
    23761 tttcgtaaat ataggactga atttcctcct gcatctcaag aggcaccatc atgaccggct
    23821 gtctggtttg aaaatcagga gcttcaccaa aaagggtcac aacccgatag cccagacttt
    23881 cccctaaaat actagctgcg gcataatccc atggttgcag ataggtgaga taggtcaaca
    23941 aatgccctga caaaatcttg gcaaaactaa tggccgcact tccatagaca cgaacaccaa
    24001 gaaccgctcg gctcaaatca gccagccccc attcattggt ttccagcata ccactattcc
    24061 ctgcaatgag aaaatctcca agtggtttag ttttaaaagg agctaggggc ctatcattta
    24121 gacaaactgg aaattcccca ccaccgtggt aacaatcccc tttgaccaca tcataaatca
    24181 gaccaaactg tccctgacca ttttcaaaat aagccatcat aacagcaaaa tcttcctgct
    24241 gggctacaaa attattggta ccatcaatgg gatcaatgac ccaaaccttg ccctcttgaa
    24301 ccgaggctcg cagacaacct tcttcagcac aaatcttatc ctcaggataa cgggacaaaa
    24361 tctcaccaac caagagttcc tgaacttctt tgtccagtct ggtcaccaaa tctgttggag
    24421 aggacttggt ttcaacacgc aagtcttcct gcatatggtc aagaatgtac tggcctgctt
    24481 tcttaacaag ctctttagca aattcaaatt tactttccaa gagaaatctt tccttcccct
    24541 ttttctttgg cagcctgaac tgctcggtaa agtgaatagc cactaaccgt ttcaaattct
    24601 cgtcccaaac gtttctcttc gctcttgctt ggcacgaccg ctttgaatcc cttataggag
    24661 tccagtaact ttttagcctc tactttgcct tcataggcag cttcaacatc attaaaaaaa
    24721 gaaagcactg aagcaagttc ttcagtgctc cacgacaaat ctagtgggta actatactgt
    24781 ttgttcatta actaatacca gctctcattc ttgcttcttt tagttcttgc ttacgataac
    24841 tacgagggag aaaagcacga atctcatctt cattaaaacc gatttgcata cgcttggcat
    24901 caataataat tggacgacgc aaaagactag gatactgctc aatcaaatga agcaattccg
    24961 ataccgaaat actctctaca tcaatattca atttttgaaa aatttttgaa cgagttgaaa
    25021 tgatgtcatc agtaccattt tcggtcaagg aaaggatgtg ttgcaattct tttcttgtta
    25081 aaggactggt cataatattg tgttccacaa agggaacctt atgtttttct aaccaggcct
    25141 tagccttacg acatgatgta cagctcggtg atagaaatag tgtaatcatg cttttctctt
    25201 cttatctata ctttgctact tctattatac aaaaaaataa ggcgcttgac tagggatttt
    25261 tagaaaaaag cctatttttt caggaaaaat aggctgtttg cgaacgattg acacaattgg
    25321 atttggttaa ttcactctta acgatggttt taaacgatat atatatattt atatgtaaat
    25381 taaaaacatc tttcctttca cttcctacga cttttcagac acagatagcc aaagaagttt
    25441 tcatagaggg caaaaaagag gaggaaggca tgaagaaaga aggtctctgg caaaatcata
    25501 ataacaggat ccttggctgg atcaaaaagc caggtatcat ctcccacaaa gagaatttga
    25561 tggaaaagag taaagaattg gtcaaaacca atcaaaactc ccccaagtcc aatcattaca
    25621 ggtaaaacta ctagagccag gagacttttt cgataaagag acaaaaagtc ctttttcaca
    25681 atcctattga caaagacata gaaacttggc agtgtcacta gagctactag ctgaaccaaa
    25741 tgaaagagat tcttgaccac tgcgaaatgg tgcagaccag ctgctgacga acgaaaatca
    25801 ggcatctgta agacctgact aaaaggattg gtcagataat tcatcaagat atgaaaattg
    25861 tattgaatgg tttctggttt tagatagact cgattcgtta agtttagcca ctgaatctcc
    25921 ataggataga aaatccaagc cagataaatg gtcagaagga tggagaggga gaggagaaag
    25981 agcatagagc cccaaaagat caatttagtt ttcatcaaaa tcccactccg caaggctaga
    26041 aaccacatgt gtcggtgcga ttggcaggcc agctacttct tctgccttag taaaacctgt
    26101 cgtcaccaag agcgttggaa tgccattgtc aatcccagcc cgaatatcag tcaaataatt
    26161 gtccccaacc atgattaact cttcacgttc caaacctaag tgctcaaccg ccttgtccat
    26221 aatgatggca tttggttttc cgatataaac cggcttcact cgtgtcgcta cttcaagcag
    26281 cgtaatcagt gagccagcac ctggcaaaag accgcgttcc gtcgggatgt tgaggtcagg
    26341 attggttccg ataaaatggg cacccttttg aatagcaaga gttgctgtgg caaatttttc
    26401 atagtcgact tgccaatcca gaccaactac cacgtaggca gggttttcct tgtcttccac
    26461 ataaccagcc gccttgatgg cttccttgag tcctgcttct ccgacgacat agacagtctt
    26521 ttcaagcccc aaatcattca tatagtcgat ggttgccaaa gtcgctgtgt agacagtcga
    26581 tagaggcgta tcgatattaa aattctgagc caacatctcc ttaacactct ctggagtgcg
    26641 ggttgtattg ttggttacaa agagataggg aatgtcccgc ttttgcaatt catgaacaaa
    26701 agtctctcca gcagggattc ggtctttccc cttataaatg gttccgtcta aatcaattaa
    26761 atagccttta tatttcatct atttctccct aaaccttttt tatttcttgc caagtaatga
    26821 ttgcttgggc attgataacc ccatcacttg taatttcatg cttgctttcc agtccagtcc
    26881 gttcaacagc cgatgtaatc accccacctg gtcgaacttc cttgacatac ttgaggttga
    26941 ttttcttggg aatatagtgg gtcaaaaaat ccgctcccat gacctcaaaa atccagtcca
    27001 agtatttact gttattgaca tgaccattca tatccaagtc gtaaaaacga acatggtaat
    27061 ccttgctgat cggctcttcc aaggattcat acttcggtcc acggataagt tttttatcaa
    27121 aatcagactg gtaaggagcc acaatctcag gttcaacagc atggactttt cgactgtcgc
    27181 ggtccatgag aacaaaggtc gccatcatat ggatgagctc ctgccccgct tcattataaa
    27241 tagtaaagcg acggtagcaa aaaagtcgat tgtagctcaa ggcttccgtt tcgatggtaa
    27301 tttcttccgc aaaacgaggc aaacgaacca cctcaatatc atattctgcg ataatccaga
    27361 ccagattata gtcttccaaa atggccttat cactaactcc cagttcaatc gattgcatcc
    27421 ctgaaacttg cagtgacagc aaaatcacat ctggaagttt gatatgaccg ttcatatcag
    27481 ccatatcaaa aggaattttc attttcattt gataagttaa gcccatgatc ctactccaaa
    27541 ataaatcgtt ctgctacagt atctcccaaa aagagacctc tctttgtcat gcgaacgtgg
    27601 tcaccctcaa tctgcatgag gccttgttga accaagtctc tgacaatttc tccataaagt
    27661 ccagcaaaag actgtccaaa tttttcctca aatcgcgcca tggaaacccc ggatttcttg
    27721 cggagtccca agaacatttc ttcttccatt tgctcctttt gactcaggtg atcttctgta
    27781 atacaagcat tgccttcctc aaccgcactg agataatgac gaatgggacc atgattttta
    27841 tagcgtactc cattgacata accagatgcc cctgcaccaa taccatagta ttcagcattg
    27901 tcccagtaca tgagattatg acgactttca aagccgggtt tggagaaatt agaaatctca
    27961 taatgctcaa aacccgctcg ctccagctct gcaatgatgt actcaaacat ctccgcttct
    28021 agttcctcct taggcagagg caatttccca cgtcgcatcc ggttcataaa gaccgtatgg
    28081 ttttctaaaa tcaaactata caaactcatg tggggaatat ccaatccaat ggctttagcc
    28141 acattttcct ttacttgctc catggtctga ccaggcagag cataaatcaa atcaatggag
    28201 atgttgtcaa aaccagccag tttcaggcga tcgatatttt cataaatatc cttctccaaa
    28261 tgactgcgcc caatcttttt caacatctta tcatcaaagg tctggacacc tagcgaaaca
    28321 cgattgacag ccgaattttt caaaacagct atcttatccg catccaaatc gcctggattg
    28381 gcttcaatgg tcaactcttc caagacagac aaatccaagt ttttagtcaa gccattcagt
    28441 aacacctcca gttgcggagc cgacagggct gtcggtgttc caccaccgat ataaagggtt
    28501 gacaactttt caatatcata agaacgaaac tcttccagca gatgctctaa atagctgtcg
    28561 actggctgat ttttgatgaa gacctttgaa aaatcacaat aataacaaat ctgggtacaa
    28621 aatgggatgt gcacataggc tgacgttggt tttttctgca tagtaattat tataccacaa
    28681 agactagatt ccagataaaa atcaccatcc ccagatacat agtccgtccg gagatggtga
    28741 tggtttattc ttctgttata tcaatcacaa tctcttctga gtcatcaaga gcttcggctt
    28801 tttcttgcca ttgttccttg agattattta attgattttt tgatgcttct gtcgcttgaa
    28861 aagcatagga tttagcttga gcaagtatac tgtccacagt gatttcacct gactcaacct
    28921 gttcttttgt tttcagaaca aaatctgtag cctgctcctt aacttctgtc agtttttcac
    28981 agacttgctc cttggcatac tccggatctt ctctcaaatc atctagaaaa tcttgagcct
    29041 gactgcaaac ttgtttgccc ttatcacttg ttaaaaacaa ggcaagagct gcacctgaaa
    29101 cggttcctaa aaggattgag gataatttac ccataaggat tctccttttt tattttttga
    29161 aaaatttact tgcaagacga agagctgaca gacttgcacc agtcttgagt gtttttgaac
    29221 cagctgatga agctttcttg ctcaagacac gcgcatggtc attgaggtct gaaacagata
    29281 gagataaatc tgcaacagca ctgaagagtg gatcaatcgt agccaccttg acattgatat
    29341 catctgccaa gacattgacc ttagccaaca actcattggt gtgatgcaag gtcacatcca
    29401 catctgaagt caaggtttta atcgtctttt ctgtttcatc gataacacga ccaagctttt
    29461 gtacagtaat gatcagatag accaaaaaga caatcacagc tagggcaaca agaatatatg
    29521 caacttctaa catttagttt tcctcctctg taatatagta aggggccttc tttcgatttt
    29581 gataaataac gatcattata ccgagaccga taaagacaac tgacagccat tgggacactc
    29641 gaaggccgaa gaacatgaga ctatctgttc gcataccttc gatgaccata cgaccgaaac
    29701 cataccaaat caagtaaaag gccgtgatat gacctcgtct gagactcttc catttccgtc
    29761 taaaaatcag aatcaaggca aagccaagca gattccatag agactcataa aggaaagtcg
    29821 gttgacggta gctcccctca atatacatct ggtcacggat aaagccaggt agataatcca
    29881 gattatccac tgttgcacca taagcttctt ggttaaagaa attaccccaa cgccccaaac
    29941 tttgagcaat cataacgcta ggcgccgcaa tatctagaaa atcccaagta ttgatgagtt
    30001 tacggtcagc aaagatatag agcacaagag ccccagttat caaaccaccg taaatggcca
    30061 aaccaccatt ccaaatggca aaaatctctc ctaaattctg actatagtaa tcaaatcgga
    30121 aaataacata gtagagacga gctcctaaaa tagccaaggg aaaggctact aagataaaat
    30181 ctaaaatatc gtctggtatg atcttctttc taggtgcttc tttcatggtc aaataaaccg
    30241 caagaatcaa gcctgtcaca atacataagg cataccaacg aatggctagg ggtcctagtt
    30301 gaatagcaat tggatcaagc attttgcacc tcatttcgag ctatgagact tgtcagtcgt
    30361 tcgtcgaaca aacgggtagc atcaaagccc atttccttgg cacgataatt catggcagct
    30421 gcctcaatca caacagagat attacgacct gttttaactg gaatacgaat acgaggaatg
    30481 gctacgccag aaacttcaag ttcctctgca ttgtttccaa gacgatcaaa ggtcttatgc
    30541 gtatcgtaat tttccaaata gacagcaagc tgaacctgtg aagaatcctt gacagcactc
    30601 gcaccgtaga gactcataac atcgataata ccaaccccac gaatttcaat caagtgtttc
    30661 aaaatttcag ctggttcacc ccagagagta atctcatcct tggcaaagat atcgacacgg
    30721 tcatcggcta ccaaacggtg accacgtttg acaagctcaa gacctgtctc gctcttacca
    30781 attccactat ctccctgaat caagacgccc atcccataaa tatccatcaa gacaccgtgc
    30841 acactggtac gttctgccaa acgagaatcc agatagctag ataactctcc agataaacga
    30901 ctggtagctg cacggctggt taaaatagca atcttacatt ctctagcagc ctttaacatc
    30961 tcctctggaa ccaccaaacc acgggcaaca atgactgctg gtgtctcagg tagaaacatt
    31021 tttttcaaaa cttcataacg gctgttggaa ggcatgctga tcagataaga ccactccttc
    31081 atccccaaaa gttgaatccg ctctggtgta tagtagtcaa aatagcctgt catttcaaga
    31141 ccaggtcgcg taatatccgc tgtattgatt tccttttcaa gcaattctgg ttcaccatag
    31201 acaatatcta gtctaagctt ttcaatcact tcttttacta aaaccgacat catttcctcc
    31261 ttcaaatgaa ttcttctctc tattatatca aattgtagga ggaagtttca gatttttgca
    31321 ggctttggag tatttattta aaagaaaaag gactagattt ctctagcctt tcatttcaat
    31381 tagaattttt tacgtttacg agctacttct gatttacgtt tacgttttac agaaggtttt
    31441 tcatagaatt cacgtttgcg tgtttcttga agagtaccag ctttagtaac cgcacgtttg
    31501 aaacggcgaa gtgcgtcgtc aagagattca ttcttacgta ctactgtttt agacattttt
    31561 ttcactccct tcaagttcaa tatctatttc attctacacg taaaaggaat aattgtcaag
    31621 caaaaatgcg gtttaatttt gattttttct tccatttata caagagttga aagcgttcaa
    31681 tagaacattg cttttttatt tttcgagtaa gctaagcgct tcagcatctg cgatgatggt
    31741 tacatcaggg tgattttgga ggctacttgc aggtaggttc tcagtcactg ggccagatac
    31801 tgttccggca atggcttctg ctttcgactc accataagca aaaagaataa tagacttggc
    31861 atccaaaatg tttttaatcc ccattgaaat agcttgggtt gggacgtctt caatcttggc
    31921 aaagaagcga gcattggctt cgatagtaga ctggtcaagt tctactagat gcgtttgact
    31981 gtcaaatgga gtaccaggct cattaaagcc gatatgccca ttgcgaccga ttcccaagat
    32041 ttggaggtca actggatggt cagccaaaat ttggttgtag cgttcaactt cagcttcagc
    32101 attgtcctta acaccacgag gcaagaaact ttctttaaat ggtttttggt tgaacaagtt
    32161 ttcttgcatg aagtaacgat aagactgtgg attgtcccca tcaaggccca catactcatc
    32221 aaggttgaca ctggttagat ttgaaaaatc aaggtcactc tcaacaattt ccttgtaaaa
    32281 ttcaagtggg ctacttcctg tcgcaagtcc tagagtttga gctccattag ccaatttttc
    32341 cttcaaaatc tcaaaagcaa cttttccacc ttgaacttgg ttttcaactt taataacttt
    32401 catcttttca tcctccattt ctgtctatat ttattatatg gtatagacca atttttgtca
    32461 agtgaaaacg atttaatttc taaaaaaaga gcgtccaaac ttgaaacgtg ttataatgga
    32521 taggattaga acttagaaag aatgaacaga tatatgaata cagctgattt tgatttccac
    32581 ttgccagagg aattgattgc ccaaacgccc cttgaaaaac gtgatgcctc caaactcctc
    32641 atcgtcaacc gtgagacagg agaaatgcaa gataaacact tccactctat tattaatatg
    32701 ctggaacctg gtgatgccct tgtcatgaac gacacccgag ttctccctgc ccgcctctat
    32761 ggtcaaaaag tggagacagg aggtcatgtg gaacttctcc tccttaagaa cactagtgga
    32821 gacgagtggg aagttctggc taaacctgcc aaacgcctca aggtcggtac tcgtatcagc
    32881 tttggtgatg gccgcctcag cgctgtcgtt acagaagaat tgacccacgg gggacgcatt
    32941 gtccgctttg aataccaagg aattttccta gaagtcttgg aaagtctggg agaaatgcct
    33001 ctgccacctt atatccacga aaaattagat gaccgtgaac gttatcaaac cgtctacgcc
    33061 aaggaaagcg gctctgctgc agcaccgact gctggtcttc acttcaccaa agaactgctg
    33121 gcagaaatcc aagctaaggg tgttcatcta gtctatctga ctctccatgt cggactcgga
    33181 acctttagac ctgtttctgt ggataatctg gacgaacacg aaatgcactc agagttctat
    33241 caactttctg aggaagctgc tgccaccctt cgctctgtca aaaaaaatgg tggtcgtgtc
    33301 atcgctgtcg gaaccacttc tatccgcacc ttggaaacta ttggttccaa gtttgatggg
    33361 caaatccaag cagattctgg ttggaccaat atctttatca aacctgggta tgagtggaag
    33421 gtcgtggatg ccttctcaac caacttccac ctgccaaaat caactctggt catgttggtt
    33481 tctgcctttg caggccgtga attagtctta gatgcctacc accattccat ccaagaacac
    33541 taccgcttct tcagttttgg tgacgccatg tttatttatt gagaaagaat ttctctaaat
    33601 cttctaatac caataaatcg ctaagatatt atttcaaaga acatctacaa ttgaaactct
    33661 agctagctgt agaagaggcc tagtacattg aaattaaaat gcttccccct agcttcgaaa
    33721 atattgccat agattgcgtt gactctccaa attgattcat ctatatttta tttcagcttc
    33781 ctatactttc ttcgctgttt gtaaatcaaa atgcaagaca catgagtagc accatatttg
    33841 ttactcttat ctgtcctctc aagagactat tatgagttat ttcagaatca ttcactactt
    33901 tgaccctgac tctccttagt ctcaaaatca aagacttata ctcttcaaaa atctcttcaa
    33961 accgcgtcaa cgtcaccttg gattatatat gtgactgact ttgtcagttc tatctacaac
    34021 ctcaaagcag tactttgagc aacctgcgac tagttttcta gtttgctctt tgattttcat
    34081 tgagtattaa acaaaaagtg aacaaatctg aattctaatg tacagaagac taggcttgtt
    34141 cactttttta tagtcgctat aagatgacct tatctatagc tttttatata taattatata
    34201 ttcagacata ctattatcaa ttttgtcgca gggaggaatc tgttaacgca cccattcacc
    34261 attatcattg actctatagc catctatact tgtattgacc gctaactcac ccgatgtatt
    34321 tacataatac catttaccac caacttggaa ccattgattg actttcatag aaccgttgct
    34381 gttgaggtag taccatgaac cattaacttg tacccaacct gttgccatgg aaccatcagt
    34441 attataaaaa taccacatac cattttcttg tttccagtct gttgttggag caactgcttt
    34501 agctggttct actgctacat ctgttccttg gttagatgta acagatacag gatacgaagg
    34561 aatagatgat tgctcaggaa caacaacttt ttcaggttct ctcgtccctc tccttatacg
    34621 tctttttacc atctctttag taatttgacg agaagtagtt tcttcaattg ttccatcacg
    34681 ttcatctaca gtatagattg tagtaagagt aatttaccaa tttctcctac ttcttctact
    34741 tcttgacttt tatcaagagt tgggccatcg agatattctg tttcgattgg aatttcttgg
    34801 acaagaactt ggggcttggt tcctttttta acaactcttg tttgagagtc ttttttttga
    34861 cttaaagtac tctcagttac ttgtccactc tttccatcta cattataagt tatcgttgta
    34921 actgttttcc cattctttcc tagagtaatc tcttgctcct gtcctgcaga aaggtcattg
    34981 tctgcttcat atttagtagc aaatggaaca agaacttctt caaccttgct tttagctgga
    35041 actttgataa ctgtatccgt ggcttctttt ctatcaacag taacctgttc ggtaacataa
    35101 ccagtctctg gattaacatc gtaggtcctt gtcgtagtta catagccatc ctctccatca
    35161 attgtaacag gattttcact acggtctttt gtttcatctt tttcataacg aattcgcgta
    35221 cttgaaattt tcttggttac taccttaggt ttagtcgcta cttttacaat aatatcccca
    35281 ttgtcagcgt catcatactc tattccctct tctttatctc tagtatcatc tctgacatat
    35341 tgaatcccat cagcagcatg aacaaaactt gtattcagat tcctcctaaa aataaagtta
    35401 gcccgattac cgcagaacca aaaatctttc cgagtttacg taatgcatag cgcttattag
    35461 tattagattt tgccattaca tcctacttct agtatagcat cttttctatc aaacattaaa
    35521 caatatactt tatatataaa atagacttag aatgatatat tgattattga actaa
//
LOCUS       DAVLUM010000013        35523 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLUM010000013 DAVLUM010000000
VERSION     DAVLUM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35523
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.013"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            68..856
                     /gene="codY"
                     /locus_tag="VYN42_000515"
     CDS             68..856
                     /gene="codY"
                     /locus_tag="VYN42_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1461640.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            856..1431
                     /locus_tag="VYN42_000516"
     CDS             856..1431
                     /locus_tag="VYN42_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1461641.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1513..1598
                     /locus_tag="VYN42_000517"
     tRNA            1513..1598
                     /locus_tag="VYN42_000517"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1547..1549,aa:Leu,seq:aag)
     gene            1881..3011
                     /gene="ugpC"
                     /locus_tag="VYN42_000518"
     CDS             1881..3011
                     /gene="ugpC"
                     /locus_tag="VYN42_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1461642.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3158..3304)
                     /locus_tag="VYN42_000519"
     CDS             complement(3158..3304)
                     /locus_tag="VYN42_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461643.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            3512..4270
                     /locus_tag="VYN42_000520"
     CDS             3512..4270
                     /locus_tag="VYN42_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1461644.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4358..4870
                     /locus_tag="VYN42_000521"
     CDS             4358..4870
                     /locus_tag="VYN42_000521"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1461645.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5052..5996
                     /locus_tag="VYN42_000522"
     CDS             5052..5996
                     /locus_tag="VYN42_000522"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1461646.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6005..6682
                     /locus_tag="VYN42_000523"
     CDS             6005..6682
                     /locus_tag="VYN42_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1461647.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6780..7538
                     /locus_tag="VYN42_000524"
     CDS             6780..7538
                     /locus_tag="VYN42_000524"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1461648.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7576..9081
                     /gene="lytC"
                     /locus_tag="VYN42_000525"
     CDS             7576..9081
                     /gene="lytC"
                     /locus_tag="VYN42_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1461649.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9577..10095
                     /locus_tag="VYN42_000526"
     CDS             9577..10095
                     /locus_tag="VYN42_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1461650.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10225..10731
                     /locus_tag="VYN42_000527"
     CDS             10225..10731
                     /locus_tag="VYN42_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1461651.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10731..10901
                     /locus_tag="VYN42_000528"
     CDS             10731..10901
                     /locus_tag="VYN42_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461652.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            10933..12165
                     /gene="clpX"
                     /locus_tag="VYN42_000529"
     CDS             10933..12165
                     /gene="clpX"
                     /locus_tag="VYN42_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1461653.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12174..12761
                     /locus_tag="VYN42_000530"
     CDS             12174..12761
                     /locus_tag="VYN42_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1461654.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12772..13152
                     /locus_tag="VYN42_000531"
     CDS             12772..13152
                     /locus_tag="VYN42_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1461655.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13204..14094
                     /gene="rapZ"
                     /locus_tag="VYN42_000532"
     CDS             13204..14094
                     /gene="rapZ"
                     /locus_tag="VYN42_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1461656.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14091..15068
                     /locus_tag="VYN42_000533"
     CDS             14091..15068
                     /locus_tag="VYN42_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1461657.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSNHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15065..15976
                     /gene="whiA"
                     /locus_tag="VYN42_000534"
     CDS             15065..15976
                     /gene="whiA"
                     /locus_tag="VYN42_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1461658.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16010..16978)
                     /locus_tag="VYN42_000535"
     CDS             complement(16010..16978)
                     /locus_tag="VYN42_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1461659.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17114..17971
                     /locus_tag="VYN42_000536"
     CDS             17114..17971
                     /locus_tag="VYN42_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1461660.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            17958..18737
                     /locus_tag="VYN42_000537"
     CDS             17958..18737
                     /locus_tag="VYN42_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1461661.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18761..20113
                     /locus_tag="VYN42_000538"
     CDS             18761..20113
                     /locus_tag="VYN42_000538"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1461662.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20187..20561
                     /locus_tag="VYN42_000539"
     CDS             20187..20561
                     /locus_tag="VYN42_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1461663.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20563..21411
                     /locus_tag="VYN42_000540"
     CDS             20563..21411
                     /locus_tag="VYN42_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1461664.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21688..22455
                     /locus_tag="VYN42_000541"
     CDS             21688..22455
                     /locus_tag="VYN42_000541"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1461665.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTAPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22467..23651
                     /locus_tag="VYN42_000542"
     CDS             22467..23651
                     /locus_tag="VYN42_000542"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1461666.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLCQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            23648..25519
                     /locus_tag="VYN42_000543"
     CDS             23648..25519
                     /locus_tag="VYN42_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1461667.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLFLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKKVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25662..26846)
                     /gene="mntE"
                     /locus_tag="VYN42_000544"
     CDS             complement(25662..26846)
                     /gene="mntE"
                     /locus_tag="VYN42_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1461668.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREESVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27150..29846
                     /locus_tag="VYN42_000545"
     CDS             27150..29846
                     /locus_tag="VYN42_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1461669.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29859..30650
                     /gene="yghU"
                     /locus_tag="VYN42_000546"
     CDS             29859..30650
                     /gene="yghU"
                     /locus_tag="VYN42_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1461670.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30766..31176
                     /locus_tag="VYN42_000547"
     CDS             30766..31176
                     /locus_tag="VYN42_000547"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1461671.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31188..32783
                     /locus_tag="VYN42_000548"
     CDS             31188..32783
                     /locus_tag="VYN42_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461672.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            32849..33013
                     /locus_tag="VYN42_000549"
     CDS             32849..33013
                     /locus_tag="VYN42_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1461673.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            33092..33820
                     /gene="yaaA"
                     /locus_tag="VYN42_000550"
     CDS             33092..33820
                     /gene="yaaA"
                     /locus_tag="VYN42_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1461674.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(33871..35355)
                     /locus_tag="VYN42_000551"
     CDS             complement(33871..35355)
                     /locus_tag="VYN42_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1461675.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILELLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
BASE COUNT        10551 a         6529 c         8133 g        10310 t
ORIGIN      
        1 ttcagataat tattgaaaaa gagacgtttt tatgttataa tgatagcgat taaattcgag
       61 gtgaaaaatg gcacatttat tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc
      121 agaggagcag ttgcaggatg agctccctta caacgctatt acgcgtcagt tagcggatat
      181 tattcattgc aatgcctgca ttatcaatag taagggacgt ctgcttggct attttatgcg
      241 ttataaaaca aatacagatc gcgtagagca attcttccaa actaagattt tcccagatga
      301 ctacgttcaa ggggctaata tgatttacga aacagaagca aacttgcctg ttgagcatga
      361 tatgagtatt ttccctgttg agagtagaga tgattttcca gatggcttga cgactattgc
      421 accgattcat gtatcgggga ttcgccttgg ttctttgatt atttggcgta atgataaaaa
      481 attcgaagat gaggacttgg ttcttgttga gattgccagt accgttgttg ggattcagct
      541 tcttaacttc caacgtgaag aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat
      601 ggcggtcaat accctttctt actccgaact ccgtgctgtt tcagcaattt taggggaatt
      661 aaatggaaat gaagggaagt tgactgcgtc agtgattgca gatcgtatcg gaatcactcg
      721 ctctgtgatt gtcaatgctc ttcgtaaact tgagtctgcg gggattattg aaagtcgctc
      781 acttggaatg aagggaacct atcttaaggt cttgatttca gatatttttg aagaagtgaa
      841 gaaaagagat tactaatgac aaaggcttta atttcgattg attatacaga agattttgtt
      901 gctgatagtg ggaagctgac agcaggtgct ccagctcagg cgatttcgga tgccatcagc
      961 aaggtaactc gattagcttt tgaacgagga gattatatct tctttactat tgatgctcat
     1021 gaagaaaacg attgtttcca tccggaaagt aagttatttc ctcctcataa tctgattggg
     1081 acgagtggac ggaatttata tggagatttg gggatctttt atcaagagca tggttcagac
     1141 agtcgtgtct tttggatgga taaacgccat tactcagctt tttcagggac tgacctagat
     1201 attcgtttga gagagcgtag agtgtctacc gttatcttaa caggtgtctt gacggatatc
     1261 tgtgtcctac atacagctat agatgcctat aatctaggat atgacatcga gattgttaaa
     1321 ccagctgttg cttccatctg gcctgaaaat catcaatttg ccctaggtca tttcaaaaat
     1381 acactcggag ctaagttagt agatgaaaat ctaaatgaac tttctgagta acctggttgg
     1441 tgaaaatgaa aaaatttgaa aaaaagtgtt gacaagcatc ccaaaagttg atatactagt
     1501 aaagtaatcg acgcggggat ggcggaattg gcagacgcgc aggactaagg atcctgtgac
     1561 cgctttaggt cgtgagggtt caagtccctc tctccgcata ggaaaagagt tagctaaagc
     1621 tagctctttt gtatttctct aaaaaattag aatccagtca aatgtagtgg agaatcagcg
     1681 aaaatatggg aaaactgatc cttgtttctg cttttgtcat agaagaataa taaagattat
     1741 cttcttcaaa ttctccgata ttctctaaag ttttgtgcaa gttgcacaga acttttttat
     1801 ttttttggtc atcttgccat agaaatataa agcgttttca tctataatat aattatcaaa
     1861 agacaaaagg agttcacctc atggtagaat tgaatcttaa aaatatttac aaaaaatatc
     1921 caaacagcga acactattca gttgaagatt tcaacttgaa catcaaagat aaagaattta
     1981 tcgttttcgt aggaccttca ggatgtggta aatcaactac actccgtatg attgctggtc
     2041 ttgaagacat tacagaaggt actgcatcta tcgatggcgt ggttgtcaac gacgtagctc
     2101 caaaagaccg tgatatcgcc atggtattcc aaaactacgc tctttaccca cacatgactg
     2161 tttatgacaa catggctttc ggtttgaaat tgcgtaaata cagcaaagaa gacattaaca
     2221 aacgtgttca agaagcagct gaaatacttg gattgaaaga attcttggaa cgtaaaccag
     2281 ctgacctttc aggtggtcaa cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg
     2341 cgaaagtatt cttgatggac gaacctttgt caaacttgga tgccaaactt cgtgtatcaa
     2401 tgcgtgctga aatcgctaaa attcaccgtc gtatcggagc tacaactatc tatgtaactc
     2461 acgaccaaac agaagcgatg acacttgcag accgtatcgt tattatgtca gctactaaga
     2521 accctgctgg tacaggtact atcggacgtg tagaacaaat cggtactcct caagaagttt
     2581 acaaaaatcc agttaacaaa ttcgttgcag gattcatcgg aagcccagct atgaacttca
     2641 tcaacgtgaa attggttggt agcgaaattg tttctgacgg tttccgtttg aaagtgccag
     2701 aaggagcatt gaaagttctt cgtgaaaaag gctacgaagg aaaagaattg atctttggta
     2761 tccgtccaga agacgtgaat gcagaacctg ctttccttga aacattccca gactgtgttg
     2821 taaaagcgac tatctctgta tcagaactgc ttggttcaga atctcacctt tactgccaag
     2881 ttggtaaaga cgagtttgtt gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa
     2941 cagttgagct tggatttgac ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa
     3001 caatctacta aaataaataa aattcaaagc actacaagaa aagatatctc tttatcaatt
     3061 gtagtggaga gatatcagtt gatctaggga gagaaacaaa atgcttctct cctttttgct
     3121 agggaagtca tattatgcat ctatattgtg atgctcttta atactcttcg aaaatctctt
     3181 caaaccacgt caacgtcgcc ttgccgtacg tatgattact gacttcgtca gttttatctg
     3241 caacctcaaa gctgtacttt gagcagctta cggctagttt cctagtttgc tctttgattt
     3301 ccattgagta ttatttgtgg gtaccatcta caagtgaagc tatatgcgta aactacgtga
     3361 gcaattgaat tcgaactaga gaggtaataa taaatttatg ctatagttat ggtgacttgt
     3421 atgcttttga ttctagttta tcaaataata gattagaatt gtcagataat atcattttgt
     3481 gttataatga agaaaaaaca gaggtgttca aatgtcagaa gcaggtcata agtttttagc
     3541 aaaattgggg aaaaaacgct tacgtccagg tggaaagcgt gccacagatt ggttaattgc
     3601 agaaggagga ttttcaaaag aaaagagaat actagaggtt gcgtgtaata ggggaactac
     3661 agcaattgag ttggcacagc gttttggttg caagataact gctgttgata tggatgctca
     3721 agctttagaa gtggctaaaa aatctgctgg aacggcaggt gttgctcatt taatcagttt
     3781 tgaaagagca aatgcaatga aacttcctta tcaagatgct agttttgata ttgttataaa
     3841 tgaagctatg ctgactatgc aagccgatca agctaagaaa aaatgtgtaa tggaatatct
     3901 aagggtatta aaacctggag gtcttctctt gacacatgat gtgcttctta aggaagctaa
     3961 agagtctatc agacaggaat tatcacaagc aattcatgta aatgtaggtc ctttaactca
     4021 agatggttgg gaacaggtga tgatagaatc aggttattgt gatgtgaaag cattgactgg
     4081 tgaaatgaca ttaatgaaat tatcgggtat gatttatgac gaaggtttgc taggaacttt
     4141 gaaaatttgt gtaaatgctt gtaaaaagga gaatagaaag cagtttttaa ctatgtataa
     4201 aatgtttgct aagaataaac agaaattggg ctttattgcg atggctagtt ataaatcgtc
     4261 aaaacgttag ataattattg aagttaactt ttcctttttt ctttcttaaa aaatatgcta
     4321 taatagagag taaaaaactt tgaaagaaag aaaaaagatg aatttaaaag attacattgc
     4381 aacaattgaa aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc
     4441 tgatggaaat gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa
     4501 agtcgacatg atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt
     4561 tgagttggga attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat
     4621 ttctgctgac tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat
     4681 taagccaggt caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa
     4741 ggcaactatc gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt
     4801 tgaattggat gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat
     4861 gcattattaa tgaaaacagt ccctagggct gttttctcta cactaggata taaaaataga
     4921 ctataactag ttagagaaaa actataattg aaaactatat cttcttgcag tataataaaa
     4981 ggactaagtg tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt
     5041 aggagagggt tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga
     5101 cagagaatat ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga
     5161 agattttaat tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc
     5221 acttggctaa tacaccccta caactggata ttgattttct ctatatggag agccaccgtt
     5281 ctaaaacaac tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg
     5341 atgagtattt tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg
     5401 aagtggacta ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt
     5461 cgacccttca tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa
     5521 aataccagat ggacagtaag ctatcaggta tttatcctca ggacacccta aaagagggtc
     5581 accttctatt tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga
     5641 tttctaagga agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg
     5701 ttggggtttc tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg
     5761 agtatgaccg tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc
     5821 cacatattcc agaaaattac tttaaagatg atgatgttaa tcaggtacct tgtctttgtt
     5881 ggtcttcatc tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga
     5941 cgccttttga ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg
     6001 aattatgaca tatttagacg cttttaaatc aggtaccttg gttttaccga gtgccctgct
     6061 cttgcatttt aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta
     6121 tttgcaaaat acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg
     6181 caaggaaatt tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca
     6241 gtatcgtact atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt
     6301 ggaacgtttg gatgacctgt ttggagcagt tcattcaagt tcagaccagc taacacctca
     6361 aaaccagctc aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc
     6421 ttttgagatt gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat
     6481 taaggaggct cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc
     6541 gattttgaga aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag
     6601 agcagaaaga gaagcaagca atcctcagtt gacacaggta tctgcagatt tcagaaatgc
     6661 catggatctc tggaaggatt aatccatgca agtaggcttg aaatccgagt aagatttgca
     6721 agctgtgtat aattgtgata gaataaatag aaaataaatt gaaaaaagag gtatgtgaaa
     6781 tgtcacgtaa accatttatc gctggtaact ggaaaatgaa caaaaatcca gaagaagcta
     6841 aagcattcgt tgaagcagtt gcatcaaaac ttccttcatc agatcttgtt gaagcaggta
     6901 tcgctgctcc agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc tcaaacctta
     6961 aagttgctgc tcaaaactgc tactttgaaa atgcaggtgc tttcactggt gaaactagcc
     7021 cacaagtttt gaaagaaatc ggtactgact acgttgttat cggtcactca gaacgccgtg
     7081 actacttcca tgaaactgac gaagatatca acaaaaaagc aaaagcaatc tttgcgaacg
     7141 gtatgcttcc aatcatctgt tgtggtgaat cacttgaaac ttacgaagct ggtaaagctg
     7201 ctgaattcgt aggtgctcaa gtatctgctg cattggctgg attgactgct gaacaagttg
     7261 ctgcctcagt tatcgcttat gagccaatct gggctatcgg tactggtaaa tcagcttcac
     7321 aagacgatgc acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct gactttggtc
     7381 aagaagtcgc agacaaagtt cgtgttcaat acggtggttc tgttaaacct gaaaatgttg
     7441 cttcatacat ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg tcacttgaag
     7501 ctgaaagctt cttagctttg cttgactttg taaaataatc agtaagtagc aaaagctagg
     7561 tggaacagca ttcagatgtc tgttacattt tttataggag agcaaagatt gaaaacaaaa
     7621 attggattag caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa
     7681 actgaagtag caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat
     7741 cagtcttcta ataaaacgca aacgagcgca gaagtacaga ctaatgctgc tgcccactgg
     7801 gatggggatt attatgtaaa ggatgatggt tctaaagctc aaagtgaatg gatttttgac
     7861 aactactata aggcttggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg
     7921 catggaaatt actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac
     7981 agtaattaca agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg
     8041 caattgattg gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa
     8101 tggcaaggaa gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat
     8161 gatccagcct attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag
     8221 tggcaaaaag tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat
     8281 gagtggcaag gcaactacta tttgactgga agtggtgcta tggcgactga cgaagtgatt
     8341 atggatggtg ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa gaaagatttg
     8401 aatgtcggct gggttcacag agatggtaaa cgctatttct ttaataatag agaagaacaa
     8461 gtgggaaccg aacatgctaa gaaaatcatt gatattagtg agcacaatgg tcgtatcaat
     8521 gattggaaaa aggttattga tgagaacgag gtggatggtg tcattgttcg tctaggttat
     8581 agcggtaaag aagacaagga attggcgcat aacattaagg agttaaaccg tctgggaatt
     8641 ccttatggtg tctatctcta tacctatgct gaaaatgaga ccgatgctga gaatgacgct
     8701 aaacagacca ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat
     8761 gatgttgaga actgggaata tgtaaataag agcaagagag ctccaagtga tacagacact
     8821 tgggttaaaa tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg
     8881 tatgtctata gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa
     8941 catgtaaact gggtagcggc ctatacgaat gctttagaat gggaaaaccc ttattattca
     9001 ggagaaaaag gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta
     9061 gatgtcagcg tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct
     9121 ttttctttgt tttatgatag ttcatcctcg agtaaattca agatcttgct cggaaatgaa
     9181 gcttatatag tagattgaat atagacaaat accttgtgat tggtaaaaca ttttagaaat
     9241 tcatttacct ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg
     9301 aatttcttca aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt
     9361 ggtcaagctg ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca
     9421 accctctttt tgtcttctaa agaattctta aattatcagt ctattgcaac ttttctcata
     9481 taagttcttt gtcttgctat tggttttcct tagtagtata ctaaggtagt aatcattaag
     9541 aagtggttac aaaaaataat gaatgaggta aagaaaatgg tagaattgaa aaaagaagca
     9601 gtaaaagacg taacatcatt gacaaaagca gcgccagtag cattggcaaa aacaaaggaa
     9661 gtcttgaacc aagctgttgc tgatttgtat gtagctcacg ttgctttgca ccaagtgcac
     9721 tggtatatgc atggtcgtgg tttccttgta tggcatccaa aaatggatga gtacatggaa
     9781 gctcttgacg gtcaattgga tgaaatcagc gaacgcttga ttacactcgg tggaagccca
     9841 ttctctacat tgacagagtt ccttcaaaat agtgaaatcg aagaagaagc tggtgaatac
     9901 cgtaatgttg aagaaagctt ggaacgtgtt cttgttatct accgttactt gtcagaactt
     9961 ttccaaaaag gtttggatgt cactgatgaa gaaggtgacg atgtgacaaa cggtatcttt
    10021 gcaggcgcta aaactgaaac agataaaaca atttggatgc ttgcagccga acttggacaa
    10081 gcacctggtt tgtaagaaat aaggaaacat agataaatct gtaggaaatt tcttacagat
    10141 tttttctatt ttgtaagcta ttccaaacca gtcttttttt gagttttttg ataaaatagt
    10201 actatcagtg aaaaggatgg aagcatgact aagaaaatcg tagctatttg ggcccaggat
    10261 gaagagggtg tgattggtaa ggaaaatcgt ctgccttggc atttgccagc agaattgcag
    10321 cactttaaag aaacaactct gaatcatgct atcttgatgg ggcgtgtgac ctttgatggg
    10381 atggggcgtc gcttgcttcc aaaacgggaa accctgattt tgacgcgtaa tccggaagaa
    10441 aagatagatg gggttgctac ttttcaggac gtccagtctg ttcttgactg gtatcaggat
    10501 caagaaaaga atctctacat tatcggtggg aagcaaattt ttcaggcttt tgaaccttac
    10561 cttgatgaag tgattgtcac tcacattcat gctcgggtgg aaggagatac ctatttccct
    10621 gaagagcttg acttgtctct ttttgagaca gtttcaagca aattttacgc caaagatgag
    10681 aagaatcctt atgattttac catccaatac cgcaagagaa aggaagtata atggaacgga
    10741 gtttatttgg tctattcacg gcttttctgt gtttcatctg ctttctggca ggagcacagg
    10801 cttttcgtaa aaagcgttac gggctttcta tcctcctttg gttaaatgcc tttaccaatc
    10861 tggtcaatag tattcatgct ttttacatga ccttatttta gatagaatga cagtatagaa
    10921 tggaaggaaa tcatgtctac aaatagaaaa aatgatatga tggtttattg ctcattttgt
    10981 ggcaaaaacc aagaagaagt acaaaaaata attgctggca acaatgcttt tatttgtaat
    11041 gaatgcgtgg agttagctca ggaaatcatt cgagaagaat tggttgagga agtcttggca
    11101 gacttgtctg aggtgccaaa accaattgaa ctcctccata tcttgaacca ctatgtaatt
    11161 ggtcaagatc gtgccaagcg tgccttggca gtggcggttt ataaccacta caaacgcatc
    11221 aatttccacg atacacgcga agagtcagaa gatgtggatt tgcagaagtc aaacattttg
    11281 atgattggcc caactggttc agggaaaact ttccttgccc agaccttggc taagagcttg
    11341 aatgtgcctt ttgctattgc ggatgcgaca gctctgacgg aggctggtta tgtgggtgag
    11401 gacgtggaaa atatcctcct caaactcttg caggttgctg actttaacat cgaacgtgca
    11461 gagcgtggca ttatctatgt ggatgaaatt gacaagattg ccaagaagag tgagaatgtg
    11521 tctatcacac gtgatgtttc tggtgaaggg gtgcaacaag cccttctcaa gattatcgag
    11581 ggaactgttg ctagcgtgcc gcctcaaggt ggacgcaaac atccacaaca agagatgatt
    11641 caagtggata caaaaaatat cctcttcatc gtgggtggtg cttttgatgg tattgaagaa
    11701 attgtcaaac aacgtctggg tgaaaaagtc atcggatttg gtcaaaataa taaggcgatt
    11761 gacgaaaaca gctcatatat gcaagaaatc atcgctgaag acattcaaaa atttggtatt
    11821 atccctgagt tgattggacg cttgcctgtt tttgcggctc ttgagcaatt gaccgttgat
    11881 gacttggttc gcatcttgaa agagccaaga aatgccttgg tgaaacaata ccaaactttg
    11941 ctttcttatg atgatgttga gttggaattt gacgacgaag cccttcaaga gattgctaat
    12001 aaagcaatcg aacggaagac aggggcgcgt ggacttcgct ccattatcga agaaaccatg
    12061 ctagatgtta tgtttgaggt gccgagtcag gaaaatgtga aattggttcg catcactaaa
    12121 gaaactgtcg atggaacgga taaaccgatc ctagaaacag cctagaggtg actatggaac
    12181 ttaatacaca caatgctgaa atcttgctca gtgcagctaa taagtcccac tatccgcagg
    12241 atgaactgcc agagattgcc ctagcagggc gttcaaatgt tggtaaatcc agctttatca
    12301 acactatgtt gaaccgtaag aatctcgccc gtacatcagg aaaacctggt aaaacccagc
    12361 tcctgaactt ttttaacatt gatgacaaga tgcgctttgt ggatgtgcct ggttatggct
    12421 atgcccgtgt ttctaaaaag gaacgtgaaa agtgggggtg catgattgag gagtacttaa
    12481 cgactcggga aaatctccgt gcggttgtca gtctagttga ccttcgtcat gacccgtcag
    12541 cagatgatgt gcagatgtac gaatttctca agtattatga gattccagtc atcattgtgg
    12601 cgaccaaggc ggacaagatt cctcgtggta aatggaacaa gcatgaatca gcaatcaaaa
    12661 agaaattaaa ctttgacccg agtgacgatt tcatcctctt ttcatctgtc agcaaggcag
    12721 ggatggatga ggcttgggat gcaatcttag aaaaattgtg aggaaaagaa aatggcaaaa
    12781 acaattcata cagataaggc cccaaaggct atcggaccct atgttcaagg aaaaatcgtt
    12841 ggcaaccttt tgtttgctag cggtcaagtt cccctatccc ctgaaactgg ggaaattgta
    12901 ggagagaata tccaagaaca gacagagcaa gtcttgaaaa acatcggtgc tattttggca
    12961 gaagcaggaa cagactttga ccatgttgtc aaaacaactt gtttcttgag cgatatgaac
    13021 gactttgttc cttttaatga ggtttaccaa acggccttca aagaggaatt cccagctcgt
    13081 tcagctgtgg aggtagctcg tcttcctcgt gatgtaaaag tcgaaattga agtcatcgca
    13141 gagattggat aagctagttg aagtttggtg ttgccaaact tcttttgata taaggagaaa
    13201 aagatgacaa agaaacaact tcacttggtg attgtgacag ggatgagtgg cgcagggaaa
    13261 actgtagcca ttcagtcctt cgaggatcta ggttatttca ccattgataa tatgccgcca
    13321 gctctcttgc ctaagttttt gcagctggtt gaaattaagg aagacaatcc taagttggcc
    13381 ttggtagtgg atatgcgtag ccgttctttc ttttcagaga ttcaagctgt tttggatgag
    13441 ttggaaaatc aagatggttt ggatttcaaa atcctctttt tggatgcggc tgataaggaa
    13501 ttggtcgctc gttacaagga aaccagacgg agtcacccac tagcagcaga cggtcgtatt
    13561 ttagatggaa tcaagttgga acgtgaactc ttggcacctt tgaaaaatat gagccaaaat
    13621 gtggtggata cgactgaact cactccacgt gagctgcgca aaacccttgc agagcagttt
    13681 tcagaccaag aacaagccca gtctttccgt atcgaagtca tgtctttcgg atttaagtat
    13741 ggaatcccga ttgatgcgga cttggtcttt gatgtccgtt tcttgccaaa tccctattat
    13801 ttaccagaac tgagaaacca aacgggtgtg gatgaacctg tttatgatta tgtcatgaac
    13861 catcctgagt cagaagactt ttatcaacat ttattggcct tgattgagcc gattctgcca
    13921 agttaccaaa aggaaggtaa gtccgttttg accattgcca tgggatgtac gggtggacaa
    13981 caccgtagtg tggcatttgc taaacgcttg gtgcaggact tatccaagaa ttggtctgtt
    14041 aatgaagggc atcgcgacaa agaccgcaga aaggaaacgg taaaccgttc atgagaaaac
    14101 caaagataac ggtgattggt ggagggactg gaattcccgt cattctaaaa agtctgcggg
    14161 aaaaagatgt ggaaatcgca gctatcgtga cggtggcaga tgatggtggt tcttcaggtg
    14221 aactccgaaa aaatatgcaa cagttgacac cgccaggtga tcttcgtaat gtccttgtgg
    14281 ccatgtcgga tatgcctaag ttttatgaga aggtctttca gtatcggttc tctgaggatg
    14341 ccggagcctt tgctggccat ccattgggaa atctcatcat tgctggcttg tcagaaatgc
    14401 agggttcaac ctataatgcc atgcagttat tgagcaaatt tttccataca acagggaaaa
    14461 tttatccttc cagtgaccat cctttgaccc ttcatgcagt ctttcaggat gggacagaag
    14521 tggctggaga gagtcatatt gtagaccatc gaggcataat tgacaatgtc tatgtgacca
    14581 atgccctaaa cgatgatacg cctctggcca gccgtcgagt agtgcagacc atccttgaaa
    14641 gtgacatgat tgtcctaggg ccaggttccc tctttacctc tattttgccc aatatcgtga
    14701 ttaaggaaat tgggcgggct cttttggaaa ccaaggcaga aattgcctat gtctgcaata
    14761 tcatgaccca acgtggggag acggaacact ttacagatag caaccacgtg gaagtcttgc
    14821 atcgtcacct tggtcgtcct tttatcgaca ctgtcttggt gaatattgaa aaagtgcctc
    14881 aggaatacat gaattccaac cgttttgatg aatacttggt gcaagtggaa cacgattttg
    14941 taggtctttg taagcaagtt tcgcgcgtga tttcatctaa cttccttcgt ctggaaaatg
    15001 gcggtgcctt ccacgatgga gatttgattg tggacgagtt gatgcgcatt atacaggtga
    15061 aaaaatgagt ttcacagtag cagtaaaaga agaaatcctg ggccaacacc atctgagctg
    15121 gcatgaatta tctgccatta tcaaaatgtc tggtagcatc ggtctctcga cttcgggctt
    15181 gactttgtca gttgtgacag aaaatgccaa actggcccgt cacctctatg agtcctttct
    15241 ccatttctat gaaatcaaat ctgaaattcg tcaccaccaa cggagcaatc ttcgcaagaa
    15301 tcgcgtctat accgttttta cagatgaaaa ggtgcaggat ttgttaagtg atttgcactt
    15361 ggcagactct ttctttggcc tggaaacagg tattgatgag gcgattttat cggatgagga
    15421 agcaggtcgt gcctatctct gtggcgcttt cttggcaaat gggagcattc gtgaccctga
    15481 gtcaggcaag taccagttgg aaatcagttc tgtttatctg gaccacgcgc aaggaattgc
    15541 ctcccttctc caacagtttt tactggatgc caaggtgctt gagcgcaaga agggggctgt
    15601 gacctatctc cagcgagcag aagacattat ggacttcttg atagtaatag gagccatgca
    15661 ggcacgtgat gattttgagc gggttaagat tttgcgagaa acccgtaacg acctcaatcg
    15721 agctaataat gccgagacag ctaatatcgc tcggacagtt tctgccagca tgaagaccat
    15781 taacaatatc agtaaaatca aagatatcat gggcttagaa aatttgccag tagatttgca
    15841 ggaagtggcg caactgagga ttcagcaccc agactactct atccagcagt tagcagatag
    15901 tctcagcacc cctctgacca aaagtggtgt caatcacaga ctcagaaaaa tcaataagat
    15961 agcggatgaa ttataaaacc acgaatccta tgtgactcgt ggttcttttt tataaactgg
    16021 tagagtgttt tggttgtact ttttgttcag ggtcaatgta gttgatagcg ttgttgacag
    16081 cagttggagc ttcccctaga cctgtcgcaa tcagatcaat ttttccgtca tagtagcagc
    16141 agtcaccgat agcatagata cctgcttggc tggattcttg tttgctgttg acgataatct
    16201 tgtgacggtt gaggtcgagc ccccagtttt taaggttacc gacagaagat ttgaaaccat
    16261 agttgacaaa gaggtggtct aggtcaatgg tttcagtttc atcagatttg acttttgtga
    16321 tttcaagttt atcaagcgtt tttccatctc caaggagttg gctaggggcg aatggtgtct
    16381 tgatggttac agatgattct tgcaaggctt gaacactgtg ttccaaggca cggaaattat
    16441 ctctgcggtg aacaagggta gttggtgcga ttttttcaaa agccaaagcc caatccacag
    16501 ccgagtctcc cccaccaaga atcgtcactt tcttaccagc gtattgctga atgttagaaa
    16561 cgtggtagtg gatattttca tagtcctcaa ccccttcaag ttccagcgga cgtggtttga
    16621 aggcaccgcc acccatagcg atgataactg ttttagtcag gtgacttcct ttggaagttg
    16681 tgatggcaaa ttcttcttct tgtttgtcaa tctcaagaac cgtttcattg agatgaatag
    16741 gggtatcaaa tccatttagc tgttcaatca agcggttagt caactcttct ccagtcaggt
    16801 ttgggaagcc tggtacgtct aggatttcct tttcagggta gagaatagca ggttgtccac
    16861 ctagctgggg aagagagtcg atgatttgaa ccttggcttg gcgtaggtgg gcataaaagg
    16921 ctgcaaaaag cccgacagga ccaccaccca caatggtaat atcatagagt tgagacatag
    16981 tttctccttt gttttttcta gtcagtttat tttatcatat ttttgttcaa tgtaaaatgg
    17041 actaggatag ggaaaaaaat gccagaaaat ggtataatag gacgaaagtg ttttgatagg
    17101 gaggatatcg gggatgaatt ttcaacaatt atccaatctg caatattgga ccagtttgtt
    17161 tgcaagtcca tggacgatag ctatcaatct gattgatatt ttgattgttg cttatatttt
    17221 ataccatttt acaaaagcta ttgcaggaac caagattatg attttggtac gtggagtttt
    17281 ggtgtttatt ttagctcaaa tccttgcaaa tatgattggt ttgactacga tttcttggtt
    17341 aatcaatcaa attattactt atggggttat tgcggcggtt gttatcttct ctccagagat
    17401 tcggactggt ttggaacgtt tgggaagagc gacagatttc ttttccaatg cccctattag
    17461 tgctgaggaa cagatgattc gtgcctttgt taagtctgtt gaatacatga gtcctcgtaa
    17521 aatcggggcc ttggttgcta ttcagcgtgt acgtaccttg caggagtata tttcgacagg
    17581 aattcccttg gatgctaaga tttctgcaga acttctcatt aacattttta ttcccaacac
    17641 tcccctacat gatggtgcgg tgattatcaa agaagaacgt atcgctgtga cgtctgccta
    17701 tctgcccttg acaaaaaaca cagggatttc caaggaattt gggaccagac accgggcggc
    17761 tatcggttta tcagaagtct cagatgcctt gacttttgtc gtatcagagg aaacgggagg
    17821 aatttcgata acctataatg gaaggtttaa gcacaaccta acacttgatg aatttgaaac
    17881 agaattacgt gaaatcttac ttccaaaaga ggaagtgggt cttagtttta aagaacgatt
    17941 gctaggagga tggaaacatg aaaaaaaata gtttatatat catatcctca ctcttttttg
    18001 cttgtgtctt atttgtctat gctacggcga cgaattttca aaacagtacc agtgctaggc
    18061 aggtaaaaac ggaaacctat actaatacag taacaaatgt ccctattgac atacgctata
    18121 atagtgataa gtattttatt agcggttttg cttcagaagt atcagtggtc ttgactggtg
    18181 caaatcgcct atcgctagct agtgaaatgc aagaaagtac acgtaaattc aaggttactg
    18241 ctgacctaac agatgccggt gttggaacga ttgaagttcc tttgagcatt gaagatttac
    18301 ccaatgggct gaccgctgtg gcgactccgc aaaaaattac agtcaagatt ggtaagaagg
    18361 ctcagaagga taaggtaaag attgtaccag agattgaccc tagtcaaatt gatagtcggg
    18421 tacaaattga aaatgtcatg gtgtcagata aagaagtgtc gattacgagt gaccaagaga
    18481 cattggatag aattgataag attatcgctg tcttgccaac tagcgaacgc ataacaggta
    18541 attacagtgg ttcagtacct ttgcaggcaa tcgaccgcaa tggtgttgtc ttaccggcag
    18601 ttatcactcc gtttgataca ataatgaagg tgactacaaa accagtagca ccaagttcaa
    18661 gcacatcaaa ttcaagtaca agcagttcat cggagacatc ttcgtcaacg aaagcaacta
    18721 gttcaaaaac gaattaaaaa tagaaaagga ttttataaca atgggtaaat attttgggac
    18781 tgatggagtc cgtggagaag ctaacctaga gctaacacca gaattagcct ttaaactagg
    18841 acgttttgga ggctatgttc ttagtcaaca tgaaacggaa gcgccgaaag tctttgtagg
    18901 acgtgacaca cgtatttcag gggaaatgct ggaatcggcc ttggtggcag gtctcctttc
    18961 agtagggatt cacgtataca aacttggtgt ccttgcaaca ccagcagtag cttacttggt
    19021 tgaaactgaa ggagcaagtg ccggtgtcat gatttctgct agccacaacc cagcccttga
    19081 taacggaatc aagttctttg gcggtgatgg cttcaaacta gatgatgaaa aagaagcaga
    19141 aattgaagcc ttgctagatg ctgaggaaga cactcttcct cgtccaagtg cagaaggctt
    19201 aggaattttg gtagattatc cagaaggctt gcgtaagtat gaaggatacc ttgtttcaac
    19261 tggaactcct cttgatggaa tgaaggttgc cttggataca gctaatggag cagcttctac
    19321 cagtgcccgt caaatctttg cagaccttgg tgcccaattg acggttatcg gggaaacacc
    19381 agacggtctt aacatcaacc ttaatgttgg ttcaacacat ccagaagccc ttcaagaagt
    19441 ggtcaaagaa agtgggtcag ctattggttt ggcctttgat ggagacagtg accgcttgat
    19501 tgctgttgat gagaatggtg acatcgtcga tggtgacaag attatgtaca tcatcggaaa
    19561 atacctttct gaaaaaggac aattggctca aaatacaatt gtgacaactg ttatgtctaa
    19621 ccttggtttc cacaaggcct tgaatcgcga aggtattaac aaggcagtta ctgcagttgg
    19681 tgaccgctac gttgttgaag aaatgagaaa atcaggttac aaccttggtg gtgaacagtc
    19741 tggtcacgtt atcttgatgg attacaatac cacaggtgat ggtcaattat cagcagttca
    19801 attgactaaa atcatgaagg aaactggtaa gagcttatca gagttggcgg cagaagtaac
    19861 gatttatcca caaaaattag ttaatatccg agtggaaaac gtcatgaagg aaaaggccat
    19921 ggaagtgcca gctatcaagg ccatcatcga gaagatggaa gaagaaatgg cggggaacgg
    19981 ccgtatcctt gttcgtccaa gtggaacaga acccctcttg cgtgttatgg cagaagcgcc
    20041 tacaacagaa gaagtagact actatgttga taccatcaca gatgtagttc gtgctgaaat
    20101 tgggattgac taaatcctag aaaactagat gaaaataaaa aattatggta caatagctta
    20161 taatattgta gccgatggag aaagacatga atcttaaacg tgaacaagaa tttgttagtc
    20221 agtatcattt tgatgcgcgt aattttgaat gggaaaatga aaatggagct cctgaaacca
    20281 aggtggatgt gaatttccaa ttgctccaac atgaccaaga aaatcaagtg acttccttga
    20341 ttgtcatctt gagctttatg attgtatttg ataagtttgt cattagtgga acaatctcac
    20401 aagtaaacca tatcgatggc cgtattgtca atgaaccaaa tgaattgaac caagaagagg
    20461 tggaaacctt ggctcgtcca tgtttgaaca tgctcaatcg tttgacttac gaagtgactg
    20521 aaattgcatt agacttacca ggaattaatt tggagttcta atatgaaatt agctgttttc
    20581 acagattcct ctgcttatct cagtgaagag accttgcaaa gagaagactt gtttgtcttg
    20641 gatattcctg tcaatattga tggtgaggaa tatgtcgaag gcatcaatct gtctgctgag
    20701 gaattttacc aaaaaatggc tcaggcttct gaattgccta agaccagtca accaagtatt
    20761 gccaagttag atgagatctt aacttcgctc aaagaacaag gctatacaca tgccttgggg
    20821 cttttcctat cttctggaat ttcaggtttt taccaaaata tccagtatat ggtcgatgac
    20881 tatgagggct taaccattgc tttcccagac actttgatta caagtgctcc cctaggcatc
    20941 atggttgaaa gcgtctttaa ttggcgtgat cagggcgatg attttgccag cattcaggat
    21001 aagctagcca ttcaaatcag ccgtacgtca gcctttatca tggtagatga cttggatcat
    21061 ttggtaaaag gtggacgcct ttcaaatggg gctgccattt tgggcaattt gcttagcatt
    21121 aagccaatcc tttattttaa cgatcaaggt gtgattgaag tttacgaaaa agttcgtact
    21181 gaaaagaagg ccaccaagcg cttaattgaa attatcaagg aaacaacggc ttcaggtcaa
    21241 taccgggtca ttgtcattca tgggaatgct cctgaaaagg ctgaagaatt gcgtcagcac
    21301 ttgcttgatt ttggcttggg ttcggatgtt tcacttgcta catttggtag tgtcattgga
    21361 acgcacctag gagcaggaag tattgctctg ggttatattc cagtgattta gttggcgctt
    21421 ctaggctagt taagatgcct tgtatcttag aaattgaaca cggactacct gcctcttgaa
    21481 aaaagatgcc tgtcttgcct ttcgtggaaa gtcagtgcca ttccctattt ttcagaggca
    21541 gctaaggtcc tttgtatctt gataattgaa cacgcctgga accctgtgtg aaaaagatag
    21601 ttcttccaag aagtagacac ttcttgattg gaattcctat tttcactttg tgttcttacg
    21661 gactttgtat cttagacagg agtagagatg agtattcgag taattattgc cggttttaag
    21721 ggaaagatgg gccaggctgc ttgtcagatg gtcttgactg ctccagactt ggacttggtg
    21781 gcagttttgg atccttttga gtctgagtca gaatggcagg gtattcctgt tttcaaggat
    21841 aaggctgatt tagctggttt tgaagcggat gtctgggtag attttactac tccagctgtt
    21901 gcctacgaaa atacacgttt tgctcttgaa aatggctttg ctccagtagt tggaacgact
    21961 ggtttcacga gtgaagaaat tgcagagcta aaagaatttt ctcgtgccca agacttgggt
    22021 ggcctgattg cccctaactt tgccttgggt gctgtcttac tcatgcaatt tgcgacgcag
    22081 gctgccaaat atttcccaaa tgtggagatt attgagctcc atcatgacaa gaaaaaggat
    22141 gctccgagtg gaacagccat taaaacagct gagttgatgg cagaggttcg agagtccatt
    22201 cagcaaggcg cagcagatga ggaagagctg attgctggtg ctcgtggtgc tgactttgat
    22261 ggtatgcgca tccactcagt tcgtttgcca ggtttggtag cccatcagga agtcatcttt
    22321 ggcaatcagg gagaagggtt gaccctccgt catgactcct atgatcgcat ctccttcatg
    22381 acaggagtca atttgggaat taaagaagtt gtcaagcgtc atgagcttgt ctatggatta
    22441 gaacacttat tatgagatta acgcaaatgc cttctgaatt tcagaaggct ttaccagtat
    22501 tagaaaaaat taaagaagca ggctttgagg cttattttgt tgggggctct gttcgagatg
    22561 cccttctcca taaccctatc cacgatgtgg atattgcgac gtcttcttat ccagaagaga
    22621 ccaagcagat ttttccgcga acagccgata tcggaatcga gcatggaacc gtcttggtct
    22681 tagatgggga tgaggagtat gaggtaacaa cctttcggac agaggatgtc tatgtggact
    22741 atcgcagacc cagtgcggtt tcctttgtgc gctcgctaga agaagacctc aaacgccgtg
    22801 atttcacagt caacgccttt gccttggatg agacaggaga aatcgttgac ttgttccatg
    22861 gtttagaaga tttggaaaag caagtcttgc gagcagttgg agtggctagt gagcgtttca
    22921 acgaagatgc tttacggatt atgcgtggtt tccgttttca ggctagtctt ggttttgcac
    22981 ttgaaccaga aacatttaaa gctatgaaga ccttgacgcc gcttttggag aacatttctg
    23041 tagagcgtac cttcgtcgag tttgataaac tcttgctggc tccattttgg agaaggggct
    23101 tggcttccat gattgagagt caagcttatg actatctccc tgatatggca tctagccagg
    23161 acaagctcaa cagactgttt gatttggaga ctgattttac ttttgaatcc tctgaacaag
    23221 cctgggcggc tttactatgg gctttggaga ttgaaaatgc gcagtcattt ttgaaatctt
    23281 ggaagacctc acgccagttt gccaagcaag ttcaggattt gctgattatt ttggctctgc
    23341 gtgaaaatgg agaattgagc aagcgagatt gttatcgctt tgacatagat ttgcttttac
    23401 aggctgaaaa tctttgtcaa gctcaaggaa aagaagtcaa cccacaagcc atcacagaaa
    23461 aataccaaag cttgactatc catgacaaga aagagattca gattaatggc ggtattttga
    23521 tcaaggaata tggctatcag ccaggcccag acttgggaga gattttaaca gagattgagt
    23581 ttgccattgt cgatggagaa ttggagaata atcgtgaagc catccatgct tacctgaggg
    23641 agaaaaaatg agtgatttta tcgttgaaaa actaagtaaa tccgttggtg acaagaccgt
    23701 ttttagggat atttccttta ttatccatga cttagacaga attggtttaa tcggtgtcaa
    23761 tgggactggc aagaccaccc ttttggacgt cctttctggt gtttctggat ttgatgggga
    23821 tgtcagtcct ttttcagcta aaaatgatta ccagattggt tacttgactc aggatcctga
    23881 ttttgatgat agaaagacag ttttggatac ggttctatct agtgaactca aggaaatcca
    23941 gctcattcgt gagtatgaat tgattatgct cgactatagt gaggacaagc aggcgcgttt
    24001 ggaacgtgtc atggcagaga tggactctct ccaagcttgg gaaatcgaaa gtcaggtcaa
    24061 gaccgttctt agcaaattgg gcattcaaga cttatctact cctgttgggg aattgtcagg
    24121 tggtctgaga agacgggtac agttggcaca agtcttactt ggcaaccacg acctcttgtt
    24181 tttggatgag ccgaccaacc atctggatat tgcgattatt gagtggctga ccctcttttt
    24241 gaaaaattct aagaagaccg tcctttttat cactcacgat cgttatttct tagacgcttt
    24301 gtcaacacgg attttcgagt tggatcgtgc aggcttgacc gagtaccagg gaaattacca
    24361 ggactatgtt cgcctaaagg cggaacagga tgagcgcgac gcggctcttc ttcacaaaaa
    24421 agaacaactc tacaaacaag aattggcctg gatgcgcaga caaccgcagg cgcgtgcgac
    24481 caagcagcag gcccgtatca atcgattcca tgatctgaaa aagaaagttt caggcagtag
    24541 tgctgagaca gacttgacca tgaactttga aaccagtcgg attgggaaga aagtcatcga
    24601 gtttcaggct gtttcctttg cctatgaaaa caagcctatt ttgcaagatt ttaatctctt
    24661 ggtgcaggcc aaagaccgta tcggaatcgt tggggacaat ggtgttggaa aatcaaccct
    24721 gctcaacttg attgcaggaa gtcttgagcc aactaaagga caagttgtga ttggggaaac
    24781 tgttcgcatc gcctatttct ctcagcaaat tgagggtttg gatgaaagca agagagttat
    24841 caattacctg caggaagtgg cagaggaggt caagaccagt ggcggttcta cgacttcgat
    24901 tgcagagttg ctggagcagt tccttttccc acgttcgacg catggaacct tgattgagaa
    24961 attgtcaggg ggtgagaaaa aacgtcttta tctcctcaaa ctgcttttgg aaaaaccaaa
    25021 tgttcttctt ttagacgagc caaccaatga cctagatatt gcaactttga cagtcttaga
    25081 gaatttcttg caaggttttg caggtcccgt tttaacagtc agtcacgacc gctatttctt
    25141 ggataaggta gcgaccaaga ttctcgcttt tgaggatggc aagattcgtc ctttctttgg
    25201 tcattacacc gactatcttg atgaaaaagc ttttgaaaca gatatggcca atcaagtgca
    25261 aaaggtcgaa aaggaaaaag tggtcaaggt tcgagaagac aagaaacgca tgacctacca
    25321 agaaaagcag gagtgggcaa gtattgaagg tgatattgaa accttggaaa aacgtatcgc
    25381 tgctattgaa gaggaaatgc aggctaacgg ctctgacttt ggtaagctgg ctactctcca
    25441 aaaagaattg gatgagaaaa atgaagcact ccttgaaaaa tacgaacgct atgagtatct
    25501 cagtgaattt gatagttaag actattcgaa aatcaaagtg caaactatgt cggcttcaca
    25561 ttgccgactc aagtacagcc tgtgaccggc ttcctaattt gcactttgat ttttattgag
    25621 tataaacgaa tagaaaaatc ccgtctcatg aaaggatttc tctattcttt tttggtttct
    25681 tgatgaaaga tattttgcca ggtttcgtgg cgacgccaga tactggtatg gatgatacca
    25741 tctaactcat agcagataag tttggttttt tgactgatgg aagtaatttg aatgtccttg
    25801 atagcagaat ttaactcttt tttggtctta taagcctctt tatccatctg ctctccatct
    25861 tggcgaatat agacaaaatc atcagtcaag agttcttcta gttggtttcc ttggtcgatc
    25921 aattgttcac gcataagcaa ttttttatag acattgtcta aaatttcatc ctcagggata
    25981 ggtgctggtt cgatatggac atcggtatca aagacgccaa aacgattctc cagcatagac
    26041 tcgacctgat ccgcgatttc atggctttca aaaacagaca agtcaggatt catctctagt
    26101 gtaatatcca ggtagatgtt gctaccgtag gtgcgacctc tttgcgattt gaccttgctg
    26161 attttgggaa tttccatgat agccttttgg tagtcctcga gcaggcggtc gtcaaagcca
    26221 tctgaaagac taaaggaaga ctcgatgaag atatcatagg cagtcttcaa gataaagaaa
    26281 gtgatgatga tagcaaccag tttatccaca atcggataat tgaaactact agctaggatg
    26341 gcaatggcgg ttccaagtga ggtaacagcg tcagaaagat tgtccttagc agctgccttc
    26401 agcgctttgg agttggattt cttactgagg cgagtattgt agagatagac cacaaacata
    26461 atcgctgcag aaatgattcc tagagttgca ccaagaggat caatgaccga ttcttcccga
    26521 ctgagaatct tttgaatggt atctcttaga acatcgaaac cgacatagaa catgatgata
    26581 gaagtgatca agcttgccaa atcttcaatc ttccaatgac caaaacggtg gtcacggtct
    26641 gcaggctggc gcgccatccg aatcccgatt aagagggcca catttccaat gatgtccgat
    26701 acgttattaa aaccatcggc caccaaactg gatgaatgaa ggagatgacc agctgctaat
    26761 ttggctgcag acaagatcaa ataggtcgaa atactgataa tggctccacg ctcagctaac
    26821 ttgagatttg agatagattg cttcattcaa cttcctttct agtcacatag cattctacca
    26881 ttatactggt tttcaaggaa aaattcaaat aaggcagttt ttactctttg aaaactcccc
    26941 aaaatttggt ataatggtac tactcaaggg agtagctggc agaaacctgt gatagtgtcg
    27001 tcattccgaa ttttatgctg aaaagtatgc tttccggccc tatcttaaac agcgagactt
    27061 gttatgatta acaggtctct ttttgtttgt cgtgaaaaga tatgacagaa agagagtctg
    27121 ttttgcacac aatgtcaagg aggagacaca tgtcaaaaga acaaaaacgc caagcgtttt
    27181 atactcagag ccctgaagag gtcttgcagg ctgtggatgc gaccgagcaa ggtttgtcat
    27241 caagtgaggc ggaaaagcgc cttgccgaat ttgggcacaa tgaactcgaa gaaggcgaga
    27301 aacgatcaat cttggtcaaa ttcatcgagc aatttaagga tttgatgatt atcatcctag
    27361 ttgcggcagc aatcttgtca gtcgtgactt ctggtgggga agatatcgca gatgccatta
    27421 tcatcctagc tgtggttatc atcaacgctg cctttggtgt ttaccaagaa ggaaaagctg
    27481 aagaagctat tgaagccctc aaatccatgt ctagtccagt tgcccgcgtt cttcgtgatg
    27541 gacacatggc agagattgac tctaaagaat tggtaccagg cgatatcgtt gcccttgaag
    27601 caggtgacgt ggtaccagcg gacctacgtt tgatagaagc caactctctt aaaattgaag
    27661 aagcagcctt gacaggtgaa tctgtaccag tcgaaaaaga cttgtcagtc gagcttgcga
    27721 cagatgctgg tattggtgac cgtgtcaaca tggccttcca aaactcaaac gtaacctatg
    27781 gtcgtgggat gggtgttgtt gtcaatacag gtatgtacac tgaagttggt catattgctg
    27841 gtatgcttca agatgcggat gagactgata caccactcaa acaaaatttg aacaaccttt
    27901 ctaaggtctt gacctatgct atcttggtca ttgcccttgt tacttttgta gtgggtgtct
    27961 tcattcaagg gaaaaatcca cttggtgagt tgttgacttc tgttgccctt gccgttgcag
    28021 ccattccaga aggacttcct gctatcgtta ccatcgttct ttctcttggt actcaagttt
    28081 tggccaaacg acattccatc gttcgtaagt tgccagcagt tgaaacactt ggttcaactg
    28141 aaatcatcgc ttctgataag actggtacgc tgactatgaa caagatgaca gtcgaaaaag
    28201 tcttctacga tgcggttcta catgactcag ctgatgatat tgaactaggt cttgaaatgc
    28261 cactacttcg ttcagttgtc ttggccaatg atacgaaaat cgatgtggaa ggtaacttga
    28321 ttggtgaccc aaccgaaaca gcctttatcc aatatgcctt ggacaagggc tatgatgtca
    28381 aaggtttctt agagaaatat cctcgtgtag ctgaattgcc atttgactct gaccgtaagc
    28441 tcatgtcaac agttcaccca ttgccagatg gtcgtttcct tgtagcagtc aagggtgcgc
    28501 cagaccaact cttaaaacgt tgtcttcttc gtgataaggc tggggatatt gctccgattg
    28561 atgagaaggt tacaaatctc attcatacaa acaattctga aatggctcat caagccttgc
    28621 gtgtccttgc aggtgcttat aagattatcg atagtattcc agaaaatctc acttctgaag
    28681 agcttgaaaa tgatttaatt tttactggtt tgattgggat gattgaccct gaacgtcctg
    28741 aagccgctga ggctgttcgt gtggctaagg aagcgggaat ccgtccaatt atgattacag
    28801 gtgaccacca agacacagcg gaagccattg ccaaacgttt gggaatcatt gacgcaaacg
    28861 atacagaagg tcacgtttta actggtgctg aactcaatga actgtcagat gaagaatttg
    28921 aaaaagtcgt tggtcaatac tctgtttatg cccgtgtgtc tccagaacac aaggttcgta
    28981 tcgtcaaggc ttggcaaaaa caaggtaaag tcgttgccat gacaggtgac ggtgtcaatg
    29041 acgcgccagc tctgaaaaca gccgatatcg gtatcggtat gggaatcact ggtacagagg
    29101 tttctaaggg ggcttctgat atgattcttg cagatgataa ctttgcgact attatcgtcg
    29161 cagtggaaga aggacgtaag gtcttctcaa acattcaaaa gactattcag tacctacttt
    29221 ctgctaatac tgctgaagta ttaaccatct tcctatcaac cttgtttggt tgggatgtct
    29281 tacagccggt tcatcttttg tggattaact tggtaacgga taccttccca gctatcgctc
    29341 ttggtgttga acctgcggaa cctggtgtca tgaatcataa accacgtgga cgcaaggcaa
    29401 gcttcttctc aggtggtgtt ttgagttcta tcatttatca aggtgtactc caagcagctc
    29461 ttgttatgag tgtttatggc cttgcgattg cttacccagt tcatgtgggt gacaatcatg
    29521 ctattcatgc agatgcccta acgatggcct ttgcaaccct tggtttgatt cagctcttcc
    29581 atgcctacaa tgtcaagtct gtctaccaat ccatcttgac agttggccca ttcaagtcta
    29641 agacctttaa ctggtccatc ttggtatcct ttatccttct catggcaaca atcgttgtag
    29701 aaccgcttga aggaatcttc cacgtaacca aactagactt gtcacaatgg ggaattgtta
    29761 tggctggaag cttctcaatg attatcatcg tcgaaatcgt taagtttatt caacgcaaac
    29821 tcggttttga caagaatgcg atttaaggga ggtttcggat gtcagcatat caattaccga
    29881 ccgtatggca ggatgaagct agtaatcaag gagcttttac ggggctaaac agaccaacag
    29941 caggtgcccg tttcgaacaa aacttgccaa aaggagaaca agcttttcag ctttattcac
    30001 tgggaacacc aaatggtgtg aaggttacta tcttattgga agaattacta gaagctggtt
    30061 ttaaggaagc ggcttacgac ttgtataaga ttgctatcat ggatggggat caattcggct
    30121 cagactttgt gaagctcaat ccaaattcca agattccagc cttattggac cagtcaggta
    30181 ctgaaaacgt aagagtcttt gagtctgctc atattcttct ttaccttgct gagaaatttg
    30241 gagccttttt accaagtaat cctgtggaaa aggtagaagt tttgaattgg ctattctggc
    30301 aagcaggtgc agcacctttt ctaggtgggg gatttggaca tttcttcaat tatgctcctg
    30361 aaaaattgga atatcctatt aaccgtttta cgatggaagt gaaacgccag ttggatttat
    30421 tggataagga attggctcag aaaccttata ttgcaggcaa tgactatacg attgcagata
    30481 ttgctatctg gtcttggtat ggacagttag ttcaaggaaa tctttaccaa ggttctgcaa
    30541 aattcttgga tgcctcaagt tatcaaaatc tagtaaaatg ggcagaaaaa attgccaatc
    30601 gtccagctgt taagcgtggc ttggaagtaa cttatacaga aattaaatag caaaaaagtc
    30661 atcttcggat ggctttttgc tacagttgag ggaaagggtt tgcagttatc ggcttttgtg
    30721 ctataattgc tataatatag taaaaagcaa gaggagtgtg aggaagtgga aaagaaaatt
    30781 gtgaaggata tcttattttt atctcaagtg tctcagccgg caagtcagga ggacctttat
    30841 cttgccagag atttgcagga tacactctta gcaaatcgtg atacctgtgt tggtctagct
    30901 gccaatatga ttggggtgca gaagcgcgtg attatcttta atcttggctt ggttcccgtg
    30961 gtcatgttta acccagtgct tctgtccttt gaaggatcct atgaggcaga agaaggctgt
    31021 ttgtccttgg taggtgtgag atcaactaag cgttatgaaa ccataagggt tgcctatcgt
    31081 gacagcaagt ggcaggaaca gaccattacc ttgacaggct tcccagctca gatttgccag
    31141 catgagctgg atcacttgga aggacgaatc atttaggagg aaagcaaatg aaacgaatag
    31201 tctttgaact tatttttatc gcaacgacct ggtatatctt tttaccgccc cttaacctga
    31261 ccagctggga atttctcttc ttcctctgtg ggcatttgtt agttgtggca atcttatttg
    31321 gctttggcaa ggggataaac cttgtcaaaa cggttcatgt gcgccacggt aaggcggaag
    31381 ctgccttaaa tcttgagggt ttcaaaatca atcggttagg gaaaattctg ttagcttcga
    31441 ttggaggaat tcttctcttg gcagctttgg tttccttggt aacttccagc atgtttcagg
    31501 ctaaaaatta tgccaatgta gtcacggtta cggaaaaaga ctttactgaa tttcctaaga
    31561 gtgacaccag taaggttcct atcctagata gaagtactgc tgaaaaaatt ggagaccgct
    31621 acttgggttc cctaaccgat aaggtgtcgc aatacgtagc ggcagatacc tatacccaat
    31681 tgacaattga tgggaaacct tatcgggtca caccactaga atatgcagac cctatcaaat
    31741 ggtttaacaa tcaagccaag ggaatcggtg agtatatcaa ggtggacatg gtaactggaa
    31801 atgcggattt ggtggacttg aagacaccaa tcaagtattc agactcggag tattttaacc
    31861 gtgatgtcaa acgtcacctg cgcttgaagt acccgaccaa aatctttaaa actccatctt
    31921 ttgaggtgga cgatgagggc aatcctttct atgtagcaac ggtttaccaa aagcaatttg
    31981 gacttgctgt tcctcgtcct gcttcagtca ttatcttgga tgctacaaat ggagaaacca
    32041 aggaatacag cttatcagat gttccagaat gggtggacag gatctatcca gcagaggaaa
    32101 ccattgagca aattaactac aacggcaagt acaaggacgg tttcttgaat gccatgattt
    32161 ccaagaaaaa cgtgacccag actaccaagg gctataatta cttgtctatc ggtaatgaca
    32221 tctatctcta cacaggtgtg acgtcggcta atgcggatga gagtaatctt ggtttcatcc
    32281 ttgaaaatat gcgaacagga gaaatcacta agtatagctt ggcttctgcg acagaagaat
    32341 cagcccgtga atcagcagaa ggtgctgttc aggagaaatc ctacaaagca accttcccaa
    32401 tcctcatcaa cctcaatgac aagcctctct acatcatggg cttaaaggac aatgctggct
    32461 tggtcaaaga gtacgccctg gtagacgcag tcgagtacca aaatgttatc gttgctacta
    32521 cagtggaaga gatgctcagc aagtatgcca ataaaaacga ccttgaaatt gacaatgcaa
    32581 cgacagaaag catcaaggga gtagtagcag acctcaaatc agctgttatc aagggagaca
    32641 ctgtctactt ctttaaagtt gatggcaaga tatacaaggt caaggcttca gtatccgatg
    32701 atcttcctta ccttgaaaat ggtaaaacct tcgaaggtca agtaggaaaa gacaattatc
    32761 tcaagacctt taagctacgg taaaaatagg ttttttcaga aagtatatgt tataatagag
    32821 taaattaaga ctaatggagg acaaagaaat gggtttttat ttgatggttg cttcaatgct
    32881 actcggactg ctcgctttga agataggttt ttctcagttc aaggagaaaa aagataaatt
    32941 cttatctatc ttaacaagtt tagctggcac agcccttgtt ctcgtggctg tctggttagg
    33001 atggcccaaa taaatagaaa aacctcggtc aaaccgaggt ttttcaaatg aatttcttgg
    33061 ttgtggctaa aaaatatgct acactatcaa tatgaaaatt ttaatcccaa cagcaaaaga
    33121 aatgaacaca gacttgccaa gtatcgaggc aattccttta aaaccagaaa gtcagaccgt
    33181 gcttgatgcc ttggctctct attctgccag tcaattggag agtttctaca aggtatcagc
    33241 tgagaaagcg gcggaagaat ttcaaaatat ccaagctttg aaaaggcaaa ctgctcaaca
    33301 ctatccagcc ttgaaacttt ttgatgggct tatgtaccgc aacattaaga gagataagct
    33361 gaccgaggcg gaacaagatt atcttgaaaa tcatgtcttc attacctcgg ctttgtacgg
    33421 tgttgttcca gccttgtcac ccatggctcc tcaccgtttg gattttttga tgaaattaaa
    33481 agtcgctggt aagactttga agagccattg gaaggcagtc tatgatgaag ctctgaagaa
    33541 ggaagaagtg attttctctc tcttgtcatc agagtttgag actgtatttt ctaaggaaat
    33601 cagagcaaag atggtgacct tcaaattcat ggaggataga ggcggtcagc tgaagattca
    33661 ctcaactatc tccaagaaag cgcgcggggc ctttctaaca gctttaatag aaaatcaagt
    33721 acaaactgtg ggggaagcac gtcgcttgaa ctttgctgga tttgtttacc gagaagattt
    33781 gtcacaacca cagggattgg tttttgtaaa ggaagtatag aaatcagata agagaaaagt
    33841 cagcacgatt atgctgactt ttttgataac ttataaagta ttggacaaat gaatctcatt
    33901 tgataaggtg ttaagatgat taaccaaatt catgattgac agatgatttc ggcaaataaa
    33961 cttcttggta atccctgaaa tatagaaatt agacacgatg atatcgtaat ctgtctgatt
    34021 taaaatctca ggacttgttt ttaattcatc ccaaatatcg aaggtaaagc ggttattaca
    34081 gtaataggaa agcatatcaa caaaggtaag ggatatagca tggtcaaagt tactgataat
    34141 caaaaccttg ataggtggtc gattttctaa caactgagta gagaggtttt cagcatgggt
    34201 taagatggtg tacatcaagt gttccaactg ttcaggatgg tcatgctgtc caattgcctg
    34261 acggtattga gccagttctt gacgcgcact tcccataaag tctgggaagt aaacttcaaa
    34321 ttttttaatc gtcaatgctt tttgttcaaa taagattggg gtagaaaaga tttcctgtct
    34381 ttcaaagaaa gcagtgttgt gtaaatgcca aatcagctca tcgtggttag taaaagtaat
    34441 cttatattgt tttgatagga gttctaatat ttgactaagt aattgataag agtatcttgc
    34501 ttgactgtta tcttctaaag agttgaagaa ttcttgagga tctaggaaaa tatcattctg
    34561 aagaaaagaa ataaaaattt gagcgattgt atctggagtc atttcaagcc caaaatgttt
    34621 agagaaataa gcaagtgtct cctggaaatt tggaatgctc tttaaaagag gataatattc
    34681 tttgtaaaag tggttgggga ggtcaatgaa gtgaccattt ttaaccctgt ggatactgat
    34741 agctatcatc agtttgtaca ttctataaat tgaaaatcgc attggataat tcgtgatttt
    34801 atagaagaag tcagcaaact ctgttaaatc ttcctcagga aggtcaggaa aaggccaatc
    34861 taggaaataa tagcgctcag aaaagtattg ggcaaaaaag taacgaatat cgatctcatt
    34921 tccacgtatc tcggatggag taaaagataa ttcaatttga aactgagatg aaagaacctt
    34981 tgtaatattt ctgcccagtc gatagaggtt ggcactacta aagtaaagat tttctattgt
    35041 tcgataaata ggtagcccct cattgaagaa catatactct agtaattgaa aagattgaga
    35101 attagcaaga aaatattgat aaatatcttc tacactagtg ttaacttcta aatctatcat
    35161 gattccgtta acagaagatt ggatgttaat agatggaaag gcaatacgta attcatttaa
    35221 atcacttttt aagattcgtt ctgtacatcc taatttttcg gctagttcat gtaatttcat
    35281 ccaattacga ttctgaatta gggtttccat taagcgtaat tgtctttgaa cttttgtgga
    35341 taaaaggttt ctcatacggg tatttcctcc ataattcatt atatcttttt ttgtctaagt
    35401 agtataaaaa aattagagca agaaaattgt cgttagtaat cggaaaaatt agaataatat
    35461 aagtggcttt taagtgcaga aacagagtat attaattgtt cagaaaatat tgattaatgc
    35521 ctc
//
LOCUS       DAVLUM010000014        35395 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLUM010000014 DAVLUM010000000
VERSION     DAVLUM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35395
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.014"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..347
                     /locus_tag="VYN42_000552"
     CDS             <1..347
                     /locus_tag="VYN42_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1461676.1"
                     /translation="QDGFRKALLSDFLKSRFKIKNRKSLDFEIIKSDIPDNLLSDVKY
                     YWKVRNIGAEAIRRNCERGAIFSGKIKHHEDSQFKGDHYVECYAVLDNTVIARDRITV
                     PIDPLCGKDFIE"
     gene            691..2025
                     /gene="trmFO"
                     /locus_tag="VYN42_000553"
     CDS             691..2025
                     /gene="trmFO"
                     /locus_tag="VYN42_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1461677.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERAFADLEEFLTV"
     gene            2109..2846
                     /locus_tag="VYN42_000554"
     CDS             2109..2846
                     /locus_tag="VYN42_000554"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1461678.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2855..3412
                     /gene="frr"
                     /locus_tag="VYN42_000555"
     CDS             2855..3412
                     /gene="frr"
                     /locus_tag="VYN42_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1461679.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3472..4326
                     /gene="cvfB"
                     /locus_tag="VYN42_000556"
     CDS             3472..4326
                     /gene="cvfB"
                     /locus_tag="VYN42_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1461680.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4335..4550
                     /locus_tag="VYN42_000557"
     CDS             4335..4550
                     /locus_tag="VYN42_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1461681.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4636..5604
                     /locus_tag="VYN42_000558"
     CDS             4636..5604
                     /locus_tag="VYN42_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1461682.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVSLYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(5582..5761)
                     /locus_tag="VYN42_000559"
     CDS             complement(5582..5761)
                     /locus_tag="VYN42_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461683.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            5797..6297
                     /locus_tag="VYN42_000560"
     CDS             5797..6297
                     /locus_tag="VYN42_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461684.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6300..6560
                     /locus_tag="VYN42_000561"
                     /pseudo
     CDS             6300..6560
                     /locus_tag="VYN42_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6928..8038)
                     /gene="ald"
                     /locus_tag="VYN42_000562"
                     /pseudo
     CDS             complement(6928..8038)
                     /gene="ald"
                     /locus_tag="VYN42_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8215..8784
                     /locus_tag="VYN42_000563"
     CDS             8215..8784
                     /locus_tag="VYN42_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461685.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8852..9502
                     /locus_tag="VYN42_000564"
     CDS             8852..9502
                     /locus_tag="VYN42_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV1461686.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9486..11726
                     /locus_tag="VYN42_000565"
     CDS             9486..11726
                     /locus_tag="VYN42_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1461687.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLPLVYDLRKNIKGLTVLSLLITGLFFLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11905..12093
                     /locus_tag="VYN42_000566"
     CDS             11905..12093
                     /locus_tag="VYN42_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461688.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12125..12712
                     /locus_tag="VYN42_000567"
     CDS             12125..12712
                     /locus_tag="VYN42_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461689.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12716..13897
                     /locus_tag="VYN42_000568"
     CDS             12716..13897
                     /locus_tag="VYN42_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461690.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    14057..14188
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14204..14734
                     /gene="infC"
                     /locus_tag="VYN42_000569"
     CDS             14204..14734
                     /gene="infC"
                     /locus_tag="VYN42_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1461691.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14767..14967
                     /gene="rpmI"
                     /locus_tag="VYN42_000570"
     CDS             14767..14967
                     /gene="rpmI"
                     /locus_tag="VYN42_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1461692.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15019..15378
                     /gene="rplT"
                     /locus_tag="VYN42_000571"
     CDS             15019..15378
                     /gene="rplT"
                     /locus_tag="VYN42_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1461693.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15436..15816
                     /locus_tag="VYN42_000572"
     CDS             15436..15816
                     /locus_tag="VYN42_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1461694.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDTFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16066..16866
                     /locus_tag="VYN42_000573"
     CDS             16066..16866
                     /locus_tag="VYN42_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1461695.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16877..17815
                     /locus_tag="VYN42_000574"
     CDS             16877..17815
                     /locus_tag="VYN42_000574"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1461696.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAKAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17857..19890
                     /locus_tag="VYN42_000575"
     CDS             17857..19890
                     /locus_tag="VYN42_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV1461697.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDYHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSTDGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(19951..21606)
                     /gene="pavA"
                     /locus_tag="VYN42_000576"
     CDS             complement(19951..21606)
                     /gene="pavA"
                     /locus_tag="VYN42_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1461698.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21711..22208
                     /gene="ybeY"
                     /locus_tag="VYN42_000577"
     CDS             21711..22208
                     /gene="ybeY"
                     /locus_tag="VYN42_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1461699.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22189..22584
                     /locus_tag="VYN42_000578"
     CDS             22189..22584
                     /locus_tag="VYN42_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1461700.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22601..23500
                     /gene="era"
                     /locus_tag="VYN42_000579"
     CDS             22601..23500
                     /gene="era"
                     /locus_tag="VYN42_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1461701.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23549..24373
                     /gene="mutM"
                     /locus_tag="VYN42_000580"
     CDS             23549..24373
                     /gene="mutM"
                     /locus_tag="VYN42_000580"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1461702.1"
                     /translation="MPELPEVETVCRSLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24373..24978
                     /locus_tag="VYN42_000581"
     CDS             24373..24978
                     /locus_tag="VYN42_000581"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1461703.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRKQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24965..26164
                     /locus_tag="VYN42_000582"
     CDS             24965..26164
                     /locus_tag="VYN42_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1461704.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQIENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26164..26313
                     /gene="rpmG"
                     /locus_tag="VYN42_000583"
     CDS             26164..26313
                     /gene="rpmG"
                     /locus_tag="VYN42_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1461705.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26353..26586
                     /gene="secG"
                     /locus_tag="VYN42_000584"
     CDS             26353..26586
                     /gene="secG"
                     /locus_tag="VYN42_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1461706.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26688..29042
                     /gene="rnr"
                     /locus_tag="VYN42_000585"
     CDS             26688..29042
                     /gene="rnr"
                     /locus_tag="VYN42_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1461707.1"
                     /translation="MKDRIKEYLQDKGKMTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVLSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEITTQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            29005..29472
                     /gene="smpB"
                     /locus_tag="VYN42_000586"
     CDS             29005..29472
                     /gene="smpB"
                     /locus_tag="VYN42_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1461708.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29488..30348
                     /gene="tehB"
                     /locus_tag="VYN42_000587"
     CDS             29488..30348
                     /gene="tehB"
                     /locus_tag="VYN42_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1461709.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30421..31374
                     /gene="coiA"
                     /locus_tag="VYN42_000588"
     CDS             30421..31374
                     /gene="coiA"
                     /locus_tag="VYN42_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1461710.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31393..33195
                     /gene="pepF"
                     /locus_tag="VYN42_000589"
     CDS             31393..33195
                     /gene="pepF"
                     /locus_tag="VYN42_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1461711.1"
                     /translation="MVLQRNEINEKDTWDISTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKVMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33197..33910
                     /locus_tag="VYN42_000590"
     CDS             33197..33910
                     /locus_tag="VYN42_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1461712.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPKAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            33977..34918
                     /gene="prsA"
                     /locus_tag="VYN42_000591"
     CDS             33977..34918
                     /gene="prsA"
                     /locus_tag="VYN42_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1461713.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(35035..35376)
                     /locus_tag="VYN42_000592"
                     /pseudo
     CDS             complement(35035..35376)
                     /locus_tag="VYN42_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        10676 a         6550 c         7982 g        10187 t
ORIGIN      
        1 cacaagatgg ttttcgaaaa gcacttcttt cagacttttt aaaaagtaga tttaagatta
       61 aaaatagaaa atctcttgat tttgaaatta taaaatcaga tattccagat aatcttttgt
      121 ctgatgttaa atattattgg aaagtgagaa atattggagc tgaggcgatt agaagaaatt
      181 gtgagcgtgg tgctattttt tcaggtaaaa taaaacatca cgaagattct cagtttaaag
      241 gagaccacta tgttgaatgt tatgctgttt tagataatac ggttatagca agagatagaa
      301 taacagtccc tatcgatccg ttatgtggaa aagattttat agagtagcat ataattgatt
      361 cttaactgga atactctcta tctctttaca tcaagaaaat gactaaacag ggaagtttgc
      421 cttcttccct ttttttgtta tactagtaga agaaaaaaat agaaagattt gtgggagtga
      481 aaaagtccag gggacttttt cagcttgagc aaagaaattc gagagcgagg aaagtccggg
      541 ggactttttc agcttgagcc aagaaattcg agagcgagga aagtctgggg gactttttca
      601 gcctgagcca agaaactcga aagcttgtaa gtctgattgg ctttttcaat gtgaatctta
      661 acttcacact cccaaagagg tattagtgtc gtgtctcaat cttatatcaa tgttatcggt
      721 gctggtttgg caggttctga agcagcttac caaatcgcag agcgtggtat tccagttaaa
      781 ctatatgaaa tgcgtggtgt caagtctaca ccccagcata aaacagacaa ttttgctgag
      841 ttggtttgtt ccaattcttt gcgtggggat gctttgacaa atgcagttgg tcttctcaag
      901 gaagaaatgc gtcgcttggg ttctgttatc ttggaatctg ctgaggctac acgtgttcct
      961 gccggtggag cccttgcggt ggatcgtgat ggtttctctc aaatggtgac cgaaaaagtg
     1021 gtcaaccacc ccttgattga agtggtgcgt gatgaaatta cagaattgcc aacagatgtt
     1081 attacagttg tggcgactgg tcccttgact agcgatgccc tggctgaaaa gattcatgcc
     1141 cttaataatg gcgatggctt ctatttctac gatgcagcag cgcctattat cgatgtcaac
     1201 actatcgata tgagtaaggt ctatctcaaa tctcgttatg ataagggaga agcagcctat
     1261 ctcaatgctc caatgaccaa gcaagagttt atggatttcc atgaagcctt ggtcaatgcg
     1321 gaagaagcac cgctcaattc ttttgaaaaa gaaaagtact ttgaaggatg tatgccaatc
     1381 gaagttatgg ccaaacgtgg cattaaaact atgctttatg gccctatgaa gccagtcggt
     1441 cttgagtatc cggacgacta cacaggacct cgtgatggag aatttaaaac accttatgcg
     1501 gttgtgcaac ttcgtcagga taatgcagct ggtagcctat acaatattgt tggtttccag
     1561 acccacctca aatggggaga acaaaagcgt gtcttccaaa tgattccggg tcttgaaaat
     1621 gcggagtttg tccgttatgg tgtcatgcat cgcaattctt acatggattc accaaatctt
     1681 cttgagcaga cttaccgttc caagaaacaa ccaaatctct tctttgctgg tcagatgacg
     1741 ggggtggaag gctatgttga gtcggcggct tcgggcttag ttgcgggaat taacgcagct
     1801 cgtctcttca aggaagaaag cgaggttatt ttccccgaga cgacagcgat tggaagctta
     1861 gctcattaca ttacccatgc cgacagcaaa catttccaac caatgaatgt caattttggg
     1921 atcatcaagg agttggaagg cgagcgtatc cgtgataaga aggctcgtta tgaaaaaatt
     1981 gcagagcgtg cctttgccga cttagaggaa tttttgactg tctaattttt ttgaaagaat
     2041 tgttcatgat actataaaaa tcttagaaat tgtgataaaa taggtaggat gaaagaagga
     2101 gagtgaaaat ggcgaatccc aagtataaac gtattttaat caagttatca ggtgaagccc
     2161 ttgccggtga acgtggcgta gggattgata tccaaacagt tcaaacaatc gcaaaagaga
     2221 ttcaagaagt tcatagctta ggtatcgaaa ttgcccttgt tattggtgga ggaaatctct
     2281 ggcgtggaga acctgcagca gaagcaggta tggaccgtgt tcaggcagat tacactggaa
     2341 tgcttgggac tgttatgaat gctcttgtga tggcagattc attgcaacaa gttggggttg
     2401 atacgcgtgt acaaacagct attgctatgc aacaagtggc agagccttat gtccgtggac
     2461 gtgcccttcg tcaccttgaa aaaggccgta tcgttatctt tggtgctgga attggttcac
     2521 cttacttctc gacagataca acagcggccc ttcgtgcagc tgaaatcgaa gcagatgcca
     2581 tcctcatggc taaaaatggt gtcgatggtg tttacaatgc cgatcctaag aaagataaga
     2641 cagctgttaa gtttgaagaa ttgacccacc gtgacgttat caataaaggt cttcgtatca
     2701 tggactcaac agcttcaacc ctctcaatgg acaacgacat tgacttggtt gtcttcaaca
     2761 tgaaccaatc aggcaacatc aaacgtgtcg tatttggtga aaatatcgga acaacagttt
     2821 caaataatat cgaagaaaag gaataagaaa gaatatggct aacgtaatta ttgaaaaagc
     2881 taaagagaga atgacccaat ctcaccaatc acttgctcgt gaatttggtg gtatccgtgc
     2941 tggtcgtgcc aatgcaagct tgcttgaccg tgtacatgta gaatactatg gagtcgaaac
     3001 tcctcttaac caaatcgctt caattacgat tccagaagcg cgtgttttgt tggtaacacc
     3061 atttgacaag tcttcattga aagacatcga acgtgccttg aacgcttctg atcttggtat
     3121 cacaccggct aatgacggtt ctgtgattcg cttggttatc ccagctctta cagaagaaac
     3181 tcgtcgtgac cttgctaaag aagtgaagaa ggtcggcgaa aatgctaaag tggctgtccg
     3241 caatatccgt cgcgatgcta tggacgaagc taagaaacaa gaaaaagcaa aagaaatcac
     3301 tgaagacgaa ttgaagactc ttgaaaaaga tattcaaaaa gtaacagacg atgctgttaa
     3361 acacatcgac gacatgactg ctaacaaaga gaaagaactt ttggaagtct aaaaataaac
     3421 agaaaaactc agttggcatt gctggctgag ttttattcga aagaaggaaa tatgaataca
     3481 aatcttgcaa gttttatcgt tggactgatc atcgatgaaa atgaccgttt ttactttgtg
     3541 caaaaggatg gtcaaaccta tgctcttgct aaggaagaag gtcaacatac agtaggggat
     3601 acggtcaaag gttttgcata cacggatatg aagcaaaaac tccgcctgac aaccttagaa
     3661 gtgactgcca ctcaggacca atttggttgg ggacgtgtca cagaggttcg taaggatttg
     3721 ggtgtctttg tggatacagg ccttcctgac aaggaaatcg ttgtgtcact cgatattctc
     3781 cctgagctca aggaactctg gcctaagaag ggcgaccaac tctacatccg tcttgaagtg
     3841 gataagaaag accgtatctg gggcctcttg gcttatcaag aagacttcca acgtcttgct
     3901 cgtcctgcct acaacaacat gcagaaccaa aactggccag ccattgttta ccgtctcaag
     3961 ctgtcaggaa cttttgttta cctaccagaa aataatatgc ttggttttat tcatcctagc
     4021 gagcgttacg cagagccacg tttggggcaa gtattagatg cgcgcgttat tggtttccgt
     4081 gaagtggacc gcactctgaa cctctccctc aaaccacgct cctttgaaat gttggaaaac
     4141 gatgctcaga tgattttgac ttatttggaa agtaatggcg gtttcatgac cttaaatgat
     4201 aagtcatctc cagacgacat caaggcaacc tttggcattt ctaaaggtca gttcaagaaa
     4261 gctttaggtg gtcttatgaa ggctggtaaa atcaagcagg accagtttgg gacagagttg
     4321 atttagggag gcttatgaga aaatcatttt acacttggct catgaccgag cgcaatccta
     4381 aaagtaacag tcccaaagca attttggcag acctcgcttt tgaagaggca gcttttccaa
     4441 aacatacaga tgattttgat gaggtcagtc gctttttgga ggagcatgcc agtttctctt
     4501 ttaacctagg agattttgac agcatttggc aggaatatct agaacactag catttattca
     4561 ttgggtttgg gctagtaatt tctccatccc tctgctataa taaaaagaaa taaaaggatt
     4621 agagaggttc tttatttgaa ggaacattca atagacattc aactgagtca tccagatgac
     4681 ctgtttcatc tttttggttc caatgaacgc catcttcgtt tgatggaaga agagcttgat
     4741 gttgtgattc atgctcgtac ggagattgtc caggttttgg gagaagagtc tgcctgtgag
     4801 gaagcccgtc aagttattca ggctttgatg gtcttggtaa atcgtgggat gaccgttggt
     4861 acgccagatg tagtcactgc gattagcatg gtcaaaaatg atgaaattga caagtttgtc
     4921 tccctttacg aagaagaaat catcaaggat aatactggga agcctatccg agtcaaaacc
     4981 ctagggcaaa agctttatgt ggacagtgtc aaacagcatg atgtgacctt tggaattggg
     5041 ccagcaggta cagggaagac cttccttgca gtgaccttgg cagtgactgc ccttaaacgt
     5101 gggcaagtca agcgaattat cctaactcgt ccagcggtgg aagcgggaga gagtcttgga
     5161 tttcttccgg gtgatcttaa ggagaaggtg gatccttacc ttcgtcctgt ttacgatgcc
     5221 ttgtatcaaa ttcttgggaa agaccaaacg actcgtctca tggagcgtga aattatcgaa
     5281 attgcgcccc ttgcctatat gcgtggtcgg accttggatg atgcctttgt cattctcgat
     5341 gaggcgcaaa acacgaccat catgcagatg aagatgttct tgacgcgttt aggctttcat
     5401 tctaagatga ttgtcaatgg agatatcagt cagattgacc tgccacgcaa tgtcaagtca
     5461 ggtttgattg atgcccaaga gaaactcaag aacatccatc agattgactt tgttcatttt
     5521 tcagctaagg atgtagttcg ccatccagtt gtcgctcaaa ttatccgagc ctatgaatat
     5581 tctactgaag ttgcacacga ctgattttga ggaagttcgc ctgcaaaaga atatactttt
     5641 gagagaggaa aatccagttg tataggctaa aggttttatc caaaggtctg agacaacgat
     5701 taggcacgat ggaaagaact tttatgtggc tgatgacgat cagtgcatct tcctgtgtca
     5761 taatcacagg gcacaagaaa gtaggaattt gaaaagatga ttgaccaact atctaagtat
     5821 tacagttgta ggatactaac tgaaaaggat attccaagta ttttatcttt atatgaaagt
     5881 aatcctctgt attttcagca ttgtccacca gagccaaatt ttgcaactgt aaaagaggac
     5941 atgctttgtc tacctgaagg taaagctaag gctgataagt tttttgttgg attttggaat
     6001 ggatctgacc ttgtggctgt tatggatttt gtctatgcat atcctgatga ggagactgtt
     6061 tttattggtt tgtttatggt tgatcaagcc tatcagagga aagggattgg tagtcatatt
     6121 gtgacagaag cactagctta ttttgctaag aactttcgaa aggcacgttt ggcttatgtt
     6181 aagggaaatc cgcaatctca gcatttttgg gaaaagcagg gctttaaatc aattggatgc
     6241 gaggttaagc aagaactcta tacggttgtt atcgctgaac agagcctaga agattagaaa
     6301 tggcatcaag taagaactat ttggaatttg ttttggaaca attatcagga ttagatgatg
     6361 tgacttaccg ttccatgatg ggggagtata ttctttactt ccgcggcaag attattggcg
     6421 gcatttatga cgatcgcttt ttagttaaac ccgtgcaagc agtcttagat aagattgacc
     6481 aatcttcttt tgagtttcca tacaaaggtg ccaaagaaat gatttgagtg gaagaacttg
     6541 ataataagat gtttctataa gacctgattt tagctatgta taaccaactg ccaacgccca
     6601 aacctaaaaa gaaaaaagca agggtgaacg aagtaaaaaa gaagtctgct aaggccctgt
     6661 ctttgcacgg gtaaaatttt atatataaaa agaagctggg actaaagagc tcagcttcct
     6721 ttggtttata taattgtcat tacaagacga agtggttggg cgaaactctg ttgactttat
     6781 tcaatttaga gtttcttatg cacaattgag tctggaacga aagtctccag ttgcaaagta
     6841 tacagtacaa taaaccaacg atgtaatagc tgatgacaca aagcacagtg ggtaggactt
     6901 gtgaagtcac ccttttcttt tcaaaattta tactaaatca ttgatatcag tgtagtcacg
     6961 attaagtcct tgagcaactg gtaggctagt caagtaacct tgataagtgg tcacaccttg
     7021 acgcaagcct tcatcttcag agattgcttg tgcgaatcct ttgccagcca aagcttcgat
     7081 ataaggaaga gtgacattgg ttagggcgat ggttgaagtg cgggtaaccg caccagggat
     7141 attggcaacg gcatagtgga gaacaccgtg tttttcatag acgggttcat cgtgcgttgt
     7201 cacacggtca gctgtttcga taaggccacc ttggtcaaca gcaaggtcaa cgatacagag
     7261 cctggacgca tttgtttgac catctcatct gtcaccaatt ccggtgcttt tgcaccaggg
     7321 atgagaatgg ctccaatcac cacatcagca tctctcacac ttgcttcaat gttgaatgaa
     7381 ttagacataa gagtttgaat ttgacttcca aagacttctt ctagaactga gagacgcttg
     7441 gcactaatat ctaaaatagt cacttgagca ccaagaccaa gggcgatgcg ggcagcatgt
     7501 gtaccgacga caccaccacc gatgatagtt acttttcctt ttggaacacc tggtacacca
     7561 ccaagtagaa caccagagcc accagcttgc ttagtaagga agtgagctcc gatttgaaca
     7621 gccatacgac ctgcaacctc actcatagga acgaggagcg gtagttgtcc ttgattgtca
     7681 cgaacagttt cataggcaat tcctgttgtt tttgctgcta acatagcatc tgctaattct
     7741 ggagcagcgg ccatgtgcaa gtagggaaga gaagaagaac gtcgcgcaag taaccgtatt
     7801 cagaacttaa aggttctttt actttcacaa ccaactctgc tgcccaagct tcaccagcag
     7861 tagcgacaat ctcagctcct tgcttttgat agtcagcatc agtaaagcca gaaccgagac
     7921 cagcatttgt ttcgataagg acacgatgac cacgactaac taagctatga acacctgcag
     7981 gtgtgagggc gacacggttt tcgttatttt taatttcttt tgggattccg attaacattg
     8041 agataaccta cctttcaatt gacggtcttg ttttggttgt cacattccag ttcataaatc
     8101 aaaaatgtga cggtttcatt gtatatgaaa ccgcttcaaa aatcaagaaa aacttgtcat
     8161 ccaaattttt ttatgctaga ctagtgaaaa tcaagctcta atggagggaa aagtatggaa
     8221 tcaatatttg tgaaatttgc ccagtatccg tctatagaaa cggagcgttt attgcttaga
     8281 cctgtaactt tggatgatgc ggaagcaatg tttgactatg cctcggacaa gggtaataca
     8341 cgttacactt ttccaaccaa tcaaagcttg gaagaaacca agaataacat tgctcagttc
     8401 tacttggcta atcccttggg acgttgggga atagaactaa aaagcaatgg tcagtttatt
     8461 ggaaccattg acttacacaa gattgatcct gttcttaaga aggtagctat tggttatatt
     8521 atcaaccaaa cgtattggaa tcaaggatta acgacagaaa ccaatcgtgc tgtgattgag
     8581 ctagcttttg agaagatagg aatgaataag ttagttgctt tatacgataa ggctaatccc
     8641 gcatcaggaa aggtcatgga gaaatcagga atgcgttttt cccatgcaga accatatgct
     8701 tgtatggacc agcatgaaaa aggccgaatc gtgacaagag ttcattatgt cttgaccaag
     8761 gaagactatt ttgcaaataa ataagcagtt gaaaagaaat ttttcgactg ttttttcttc
     8821 ctcttacgaa taatctaaga gaggagaaaa tatggaagca attatcgaga aaatcaaaga
     8881 gtataaaatc atcgtcatct gtactggtct gggcttgctt gtaggcggat ttttcctgct
     8941 aaagccagct ccacaaacac ctgtaaagga aacgaatttg caggctgaag ttgcagctgt
     9001 ttccaaggat ttggtatccg aaaaggaagt gaacaaggaa gagaaggaag aaccagttga
     9061 acaagatcta atcacagtag atgtcaaagg tgctgtcaaa tcgccaggga tttatgactt
     9121 gcctgtaggt agtcgagtca atgatgctgt tcagaaggct ggtggcttga cagagcaagc
     9181 agacagcaag tcgctcaatc tagctcagaa agttagtgat gaggctctgg tttacgttcc
     9241 tactaaggga gaagaagcag ttagtcaaca gactggttcg gggacagctt cttcaataag
     9301 caaggaaaag aaggtcaatc tcaacaaggc cagtctggaa gaactcaagc aggtcaaggg
     9361 actgggagga aaacgagctc aggacattat cgaccatcgt gaggcaaatg gcaagttcaa
     9421 gtcagtagac gagctcaaga aggtctctgg cattggtggc aaaacaatag aaaagcttaa
     9481 agactatgtt acagtggatt aagaatttct ctattcccct aatttacctg agttttctat
     9541 tactttggct ttattacgct attttctcag catcttatct tgctttgttg ggctttgttt
     9601 ttctgctagt ctgtctcttt atccaatttc cgtggaaatc tgctggtaaa gttctaataa
     9661 tttgcggaat ctttggattt tggtttgttt ttcaaaattg gcaacagagt caagcgagtc
     9721 aaaatctggc ggattctgtt gaaagggtac ggattttgcc tgatactatt aaggttaatg
     9781 gtgatagtct atcctttcgt ggcaagtcta acggtcgtgc tttccaagtc tattataaac
     9841 tccagtccga ggaggagaaa gaagcctttc aagctttaac cgacctgcat gagataggac
     9901 tagaagggaa gctttcggag ccagaagggc agagaaattt tggtggcttt aattaccaag
     9961 cctatctgaa gactcaggga atttaccaga ctctcaatat caaaacaatc cagtcacttc
    10021 aaaagattgg cagttgggat ataggagaaa acttgtccag tttacgtcga aaggctgtgg
    10081 tttggattaa gacgcacttt ccagacccta tgcgcaatta catgacagga ctcttgctgg
    10141 gacatctgga caccgacttt gaggagatga atgagcttta ttccagtcta ggaattatcc
    10201 acctctttgc cctatctggc atgcaggtag gttttttcat gaatggattt aagaaacttc
    10261 tcttgcgatt gggcttgacc caagaaaagt tgaaatggct gacttatccc ttttccctta
    10321 tctatgcggg actaactgga ttttcagcat cggttattcg cagtctcttg caaaagctac
    10381 tggctcaaca tggggttaag ggcttggata attttgcctt gacagtgttt ctcctcttta
    10441 ttgtcatgcc aaactttttc ttgacagcag gaggagtctt gtcctgcgct tatgctttta
    10501 tcctgaccat gaccagcaaa gaaggggagg ggctcaaggc tgttgctagt gaaagtctag
    10561 tcatctcctt gggcatattg cccattctat ccttctattt tgcggaattt caaccttggt
    10621 ctatcctttt gacctttgtc ttttcctttc tatttgactt gaccttctta ccgctcttgt
    10681 ctatcttatt tgtcctttcc tttctctatc cagtcattca gctgaacttt atctttgaat
    10741 ggttggaggg cattattcgc ttggtctcac aggtggcaag taggcctcta gtctttggac
    10801 aacccaatga atggctttta atcctattgt taatttcttt gcctttggtc tatgatttga
    10861 ggaaaaacat taaaggatta acagtattga gtttattgat tacaggtctc tttttcctta
    10921 ccaagcatcc actggaaaat gaaatcacca tgctggatgt ggggcaagga gaaagtattt
    10981 tcctacggga tgtaactggg aaaaccattc tcatagatgt aggtggtaag gcagaatctt
    11041 ataagaaaat caaaaaatgg caagaaaaga tgacgaccag caatgcccag cgaaccttga
    11101 ttccctatct caaaagtcgg ggagtagcta agattgacca gctaattttg actaacacgg
    11161 acaaggagca tgttggagat ttgtcagaga tgaccaaggc tttccatgta ggggagattc
    11221 tagtatcaaa agacagtctg aaacagaagg aatttgtggc agaattacag gcgactcaaa
    11281 caaaggtgcg tagtatgata gtaggggaga acttgcccat ttttggaagt cagttagaag
    11341 ttctatctcc aaggaaaatg ggagatggag gacacgatga taccctagtt ctgtatggga
    11401 aattcttgga taagcaattt ctcttcacgg gaaatttgga ggagaaagga gagaaggact
    11461 tgctgaagca ctatccagac ttgaaagtaa atgttttgaa agctagccaa catggcaata
    11521 aaaaatcatc aagtccagcc tttctagaaa aactcaaacc agagcttact cttatctcag
    11581 ttggaaagag caatcgaatg aaactccccc atcaggaaac attgacacga ctggaaggta
    11641 tcaatagcaa agtttatcga actgaccagc aaggagctat acgttttaag gggttggata
    11701 gttggaaaat cgaaagtgtt cgataggaag gataaatgtt gtagattagt gaaataaact
    11761 aaaaatttgt tgcataataa tgataaaaat ggtataatga aaacgtattc aatattgagt
    11821 atataaaatc attaaaaatt agcaaaagtt gttttattag ttagtttata atctattggt
    11881 cttcttcagt ccagtgtatc tgctgtgaca gccactaaaa gttacaagta tgattggaat
    11941 acggttttgg aatatagtac caactatcac gaccatcagt atgcttggat tccggaatgg
    12001 tctcgttatt acagctattc tgagtataaa gttggcggag gctggaacta cgctcgttat
    12061 gaggtcataa actactatac tggaggttat taatccttaa agagtgagaa aaggagggct
    12121 ggatatgtta aatcttactc atgttacctt aaaaacgcga caagtcatct tgcaagatgc
    12181 ggattttacc tttaaaaagg gtaggattta tggccttctt gctatcaatg gctcgggaaa
    12241 gacgacacta ttccgagcta tgagcaagtt gcttcccctt agtagtggac acatcgcagt
    12301 tcctccttct ttgttttatt atgagagcgt tgaatggctg gatggaaact taagtgggat
    12361 ggactacctt cgtctcataa aaaacatctg gaagtcagac ctaaacttga gagatgaaat
    12421 cgcctactgg gaaatggctg actatatcag tcttcccatc cgcaagtatt ccttaggcat
    12481 gaagcaacgc ttggtgattg ctatgtattt tctcagtcag gccaaatgct ggctcatgga
    12541 tgagattaca aatggcttag acgagtatta tcgacagaag ttttttgata ggctagcaca
    12601 aatcgataga caagaacagc tggttctttt aagttcccac tataaggaag agttggttga
    12661 tatctgcgat agagtagtaa ccattcatca ggggcagata gaagaggttt agtttatgaa
    12721 agatgttagt ctatttttat tgaaaaaagt tttcaaaagt cgtttaaact ggattatctt
    12781 acttttattt gcatctgtac tcggtgttac cttttattta aatagtcaga ctgcaaactc
    12841 acacagcttg gagagcaggt tggaaagtcg cattgcagcc aacgagaggg ctatcaatga
    12901 aaatgaagag aaactctccc aaatgtctga taccagctcg gaggaatacc agtttgctaa
    12961 aaataattta gacgtgcaaa aaaatctttt gacgcgaaag acagaaattc taactttact
    13021 aaaagaaggg cgctggaaag aagcctacta tctgcagtgg caagatgaag agaagaatta
    13081 tgaatttgta tcaaatgacc cgactgctag ctctggctta aaaatggggg ttgaccgcga
    13141 acggaagatt taccaagccc tgtatccctt gaacataaaa gcacatactt tggagtttcc
    13201 gacccacggg attgatcaga ttgtctggat tttagaggtt atcatcccaa gcttgtttgt
    13261 ggttgcgatt atttttatgc taacacaact atttgcagaa agatatcaaa atcatctgga
    13321 cacagctcac ttatatcctg tttcaaaagt gacatttgca atatcctctc ttggagttgg
    13381 agtgggatat gtaactgtgc tgtttatcgg aatctgtggc ttttcttttc tagtgggaag
    13441 tctgataagt ggttttggac agttagatta tccctaccca atttatagct tagtgaatca
    13501 agaagtaact attgggaaaa tacaagatgt attatttcct ggcttgctct tagctttctt
    13561 agcctttatc gtcattgtgg aagttgtgta cttgattgct tactttttca agcaaaaaat
    13621 gcctgtcctc tttctttcac tcattgggat tgttggctta ttgtttggca tccaaacaat
    13681 tcagcctctt caaaggattg cacatctgat tccctttact tacttgcgtt cagtggagat
    13741 tttatctgga agattatcta agcagattga taatgtcgat ctaaattgga gcatggggat
    13801 ggtcttactt ccttgcctga ttatcctttt gttagtgggg attctattta tcgaaagatg
    13861 gggaagttca cgtaaaaagg aagtttttaa agtttagttt tcctataggg aagctaaaga
    13921 aaaactaaca tagggagaga atcaacttgg ttctctcttt ttgattcgaa aaccaaacca
    13981 aaatacaaac acaaactttt caaaaaataa ctttttatct tgacaagagc tagaaaactt
    14041 ggtatcatat aaaagttgag aaaagcagaa gtgagagctt ctcgccttgt gacattaagt
    14101 tgcctggccc tacggatgaa aagtttcgaa gaaacgctat cataacgtgc gggcttgtat
    14161 atttacgagt ccgctattgt ttttctctaa taaaacaaaa gaggtgaaaa ccatagcaaa
    14221 gcaagactta ttcatcaatg atgagattcg tgtacgtgaa gttcgcttga ttggtcttga
    14281 gggagaacag ctaggcatca agccactcag tgaagcgcaa gctttggctg ataacgctaa
    14341 tgttgaccta gtattgattc aaccccaagc caaaccgcct gttgcaaaaa ttatggacta
    14401 cggtaagttc aaatttgagt accagaagaa gcaaaaagaa caacgtaaaa aacaaagcgt
    14461 tgttactgtg aaagaagttc gtctaagtcc aacaattgac aagggtgact ttgatacaaa
    14521 acttcgtaat gcacgtaagt tccttgaaaa aggaaataaa gttaaggtat ctattcgctt
    14581 taagggtcgt atgattaccc ataaagagat tggtgcaaaa gttttagccg agtttgctga
    14641 agcaactcaa gatattgcca tcatcgaaca acgtgctaaa atggatggac gtcaaatgtt
    14701 catgcaattg gcgccagcga ctgacaaaaa ataattgtca gaaagttaaa taaaggagaa
    14761 aaaatcatgc caaaacaaaa aacacaccgc gcatcagcta aacgtttcaa acgtacaggt
    14821 tctggtggac ttaaacgttt ccgtgcttac acttctcacc gtttccacgg aaaaactaag
    14881 aaacaacgtc gtcatcttcg taaagcatct atggtgcatt caggagatta caaacgtatc
    14941 aaagcaatgc ttactcgctt gaaataatag cttgactgta agtaaacaat tctagaaaat
    15001 atttggagga aataaaacat ggcacgtgtt aaaggtggcg ttgtatcacg caaacgtcgt
    15061 aaacgtattc ttaaattagc aaaaggttac tatggagcta aacacatctt gttccgtact
    15121 gcaaaagaac aagtaatgaa ctcttactac tatgcatacc gtgaccgtcg tcagaaaaaa
    15181 cgtgacttcc gcaaattgtg gattactcgt atcaatgcgg cggctcgtat gaacggactt
    15241 tcatactcac aattgatgca tggtttgaaa ttggctgaga tcgaagttaa ccgtaaaatg
    15301 cttgctgact tggctgttaa cgatgcagta gctttcacag ctcttgcaga tgcagctaaa
    15361 gcaaaacttg gtaaataaca actgatgaga ctggaacagg attgtccagt ctttttaaaa
    15421 ataaaggaga aagatatggc ttcaaaaatg ctacacactt gcttacgagt agaaaatctt
    15481 gaaaaatcaa tcgcatttta tcaagatact tttggtttta aagaattgcg tcgcagagat
    15541 tttccagacc atgccttcac gattgtctat ctaggtcttg agggtgatga ttatgagttg
    15601 gagttgactt ataactacga tcacggtccg tatgtggttg gtgatgggtt tgcccatatc
    15661 gccctcagta cacctgatct tgaggcactt catcaagaac acagtgcaaa aggctatgaa
    15721 gtgactgagc caaatggtct accaggaact acaccaaact attactttgt taaagaccct
    15781 gatggatata aggtcgaagt cattcgtgaa aaataatttc gtgcaagtta agtagaatat
    15841 tcgttttcta cttgactttt tttagctgaa agagtatact aataaaaatt caacctttaa
    15901 ggggagtcca gagagactca caaggtgtca gataaaagaa tagtgcaatt ttctagagga
    15961 gaccttttga gtgtgctctc ttgtgttgta cgattttaac tgaggccttg cactagcaag
    16021 gtcttttctt tatctggtcc ccttaaaatt taaggaggaa aagttatgaa tctcacatgt
    16081 aagaagcgtt tgggtgtcat tcggttggaa accatgaagg tggttgcaca agaggaaatc
    16141 gcgccagcaa tctttgaatt agtcctagaa ggagaaatgg ttgaagccat gcgagcaggc
    16201 caatttcttc atctgcgtgt accggacgat gcccatctct tacgtcgtcc tatttcaatt
    16261 tcgtctattg acaaggcaaa caagcagtgt cacctcattt atcggattga gggagctggg
    16321 actgcaattt tttcaacctt aagtcaggga gacactcttg atgtgatggg gcctcaggga
    16381 aatggttttg acttgtctga ccttgatgag cagaatcagg ttctccttgt tggtggtggg
    16441 attggtgttc cacccttgct tgaggtggcc aaggaattgc atgaacgtgg agtgaaagta
    16501 gtgacagtcc tcggttttgc taataaggat gctgttattt tgaaaacgga attggctcag
    16561 tatggtcagg tctttgtaac gacagatgat ggttcttatg gcatcaaggg aaatgtttcc
    16621 gttgttatca atgatttaga tagtcagttt gatgctgttt actcgtgtgg ggctccagga
    16681 atgatgaagt atatcaatca aacctttgat gatcacccaa gagcctattt atctctggaa
    16741 tctcgtatgg cttgtgggat gggagcttgc tatgcctgtg ttctaaaagt accagaaagc
    16801 gagacggtca gccaacgcgt ctgtgaagat ggtcctgttt tccgcacagg aacagttgta
    16861 ttataaggag aaaattatga ctacaaatcg attacaagtg tctctacctg gtttggattt
    16921 gaaaaatccg attattccag catcaggctg ttttggcttt ggacaagagt atgccaagta
    16981 ctatgattta gaccttttag gttctattat gatcaaggcg acaacccttg aaccacgttt
    17041 tgggaatcca actccaagag tggcagagac gcctgctggt atgctcaatg caattggctt
    17101 gcaaaatcct ggtttagagg ttgttttggc tgaaaagcta ccttggctgg aaagagaata
    17161 tccaaatctt cctattattg ccaatgtagc tggtttttca aaacaagagt atgcagctgt
    17221 ttctcatggg atttccaagg caactaatgt aaaagctatc gagctcaata tttcttgtcc
    17281 caatgttgac cactgtaatc atggactttt gattggtcaa gatccagatt tggcttatga
    17341 tgtggtgaaa gcagctgtgg aagcctcaga agtgccagtt tatgtcaaat taaccccgag
    17401 tgtgaccgat atcgttactg tcgcaaaagc tgcagaagat gcgggagcaa gtggcttgac
    17461 catgatcaat actctggttg gaatgcgctt tgacctcaaa accagaaaac caatcttggc
    17521 caatggaaca ggtggaatgt caggtccagc agtctttcca gtagccctca aactcatccg
    17581 ccaagtagcc caaacaacag acctgcctat cattggaatg gggggagtgg attcggctaa
    17641 agctgcccta gaaatgtatc tggctggggc atctgctatc ggagttggaa cagctaactt
    17701 taccaatcct tatgcctgcc ctgacatcat cgaaaattta ccaaaagtca tggataaata
    17761 cggtattagc agtctggaag aactccgtca ggaagtaaaa gagtctctga ggtaaactgc
    17821 aatcaatctg ttcttgattt tttattagtt tgtaatatga atttaggaga attttggtac
    17881 aataaaataa ataagaacag aggaagaagg ttaatgaaga aagtaagatt tattttttta
    17941 gctctgctat ttttcttagc tagtccagag ggtgcaatgg ctagtgatgg tacttggcaa
    18001 ggaaaacagt atctgaaaga agatggcagt caagcagcga atgagtgggt ttttgatact
    18061 cattatcaat cttggttcta tataaaagca gatgctaact atgctgaaaa tgaatggcta
    18121 aagcaaggtg acgactattt ttacctcaaa tctggtggct atatggccaa atcagaatgg
    18181 gtagaagaca agggagcctt ttattatctt gaccaagatg gaaagatgaa aagaaatgct
    18241 tgggtaggaa cttcctatgt tggtgcaaca ggtgccaaag taatagaaga ctgggtctat
    18301 gattctcaat acgatgcttg gttttatatc aaagcagatg gacagcacgc agagaaagaa
    18361 tggctccaaa ttaaagggaa ggactattat ttcaaatccg gtggttatct actgacaagt
    18421 cagtggatta atcaagctta tgtgaatgct agtggtgcca aagtacagca aggttggctt
    18481 tttgacaaac aataccaatc ttggttttac atcaaagaaa atggaaacta tgctgataaa
    18541 gaatggattt tcgagaatgg tcactattat tatctaaaat ccggtggcta catggcagcc
    18601 aatgaatgga tttgggataa ggaatcttgg ttttatctca aatttgatgg gaaaatagct
    18661 gaaaaagaat gggtctacga ttctcatagt caagcctggt actacttcaa atccggtggt
    18721 tacatgacag ccaatgaatg gatttgggat aaggaatctt ggttttatct caaatctgat
    18781 gggaaaatag ctgaaaaaga atgggtctac gattatcata gtcaagcttg gtactacttc
    18841 aaatccggtg gttacatgac agccaatgaa tggatttggg ataaggaatc ttggttttac
    18901 ctcaagtctg atggcaaaat ggctgaaaaa gaatgggtct acgattctca tagtcaagcc
    18961 tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga tggttatcag
    19021 cttggaagcg atggtaaatg gcttggagga aaagctacaa atgaaaatgc tgcttactat
    19081 caagtagtgc ctgtcacagc caatgtttat gattcagatg gtgaaaagct ttcctatata
    19141 tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa gcgcttggct
    19201 attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc gctagatgct
    19261 agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca ctatgtggct
    19321 cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg caagaaatat
    19381 tattcgacag atggcctgca ttttgatggt tttaagcttg agaatccctt ccttttcaaa
    19441 gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt tagtttgcta
    19501 aacattaaca atagcctttt ggagaacaag ggcgctactt ttaaggaagc cgaagaacat
    19561 taccatatca atgcccttta tctccttgcc catagtgccc tagaaagtaa ctggggaaga
    19621 agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga tacgacccct
    19681 tacctttctg ctaagacatt tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg
    19741 attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc ttctggtatg
    19801 aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa
    19861 atcaatgaga agctaggtgg caaagattag tactataagt gaatatgatt tgagtgaata
    19921 gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg caattttttt
    19981 ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc
    20041 accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca gattcgacag
    20101 gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtcttgactg catcagatgg
    20161 gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat ggaaccaaag
    20221 ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac
    20281 atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc gtttctggat
    20341 tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac ggatttcagc
    20401 gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat agagaatagt
    20461 ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga gtttctgata
    20521 ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa gcgcaatcat
    20581 gataggttgg ttggtatagt agttgtctag gataacctgg tcttggtcgt taggcacttg
    20641 gtggaggaag gttgtcagca attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc
    20701 cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt cattttcaac
    20761 acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct tatccttata
    20821 gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat ttgcaaaagg
    20881 aactggactg aaggaagtct cagtcaagca tggcttggtt tcttgattga aaaaatttcg
    20941 gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg tatcgcgtcc
    21001 cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt gcaggatttc
    21061 aaagagcttt tcatccttta tagtaaaagg attgagagat tttgtacttg gcggagcgat
    21121 ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaagccga cgtgtttgat
    21181 aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt gtttccccat
    21241 aatttcgata atcaaggtag cctggatatg gtctccaatc tcgtttttat tggaaactgt
    21301 aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa
    21361 atactttctc aaaaccatga taaaggtaga aggttgggct ggattttcaa aagtcgtttg
    21421 ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat ggctttggcg
    21481 attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt tctggatgcg
    21541 accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa atccgtcaaa
    21601 tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag gtagaataaa
    21661 atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac atgtatattg
    21721 aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc caagaaattt
    21781 tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc acttttgtga
    21841 ccaatgagcg tagtcatgaa cttaatctgg agtaccgtga caccgaccgt ccgacagatg
    21901 tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag gatttgcttg
    21961 aaaatccaga attggcagag atgatgtctg agtttgatgc ctatattggg gaattgttca
    22021 tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt gagcgtgaga
    22081 tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac tacactccgg
    22141 aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat ggactcacaa
    22201 gacaataaac gaaaatggaa aaatcgtgac ttgatatcca gtttagaatt tgctttgaca
    22261 ggtattttta ctgctatcaa ggaagaacgc aatatgcgaa aacacgcagt gacggctcta
    22321 gtggtcatcc ttgcaggttt tggttttcag gtgtcacgaa tcgaatggct ctttctccta
    22381 ttgagtattt tcttggtagt agcctttgag attatcaact ctgctattga aaatgtggtg
    22441 gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga tatggcggct
    22501 ggcgcggtat tagtggtttc tcttttcgca gccttaacag gcgcattgat ttttctccca
    22561 cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta aatcaggctt
    22621 tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc acgttatggg
    22681 gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat
    22741 ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc acaaacctaa
    22801 aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg aagtggacac
    22861 cgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata tgattatcga
    22921 gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg aataaaatcg ataaggtcca
    22981 tccagaccag ctcttgtctc agattgatga cttccgtaat caaatggact ttaaggaaat
    23041 tgttccaatc tcagcccttc agggaaataa cgtgtctcgt ctagtggata ttttgagtga
    23101 aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagacc atccagaacg
    23161 tttcttagtt tcagaaatgg ttcgcgagaa agtcttgcac ctaactcgtg aagagattcc
    23221 gcattctgta gcagtagttg ttgactctat gaaacgagac gaagagacag acaaggttca
    23281 catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca tcggtaaagg
    23341 tggcgctatg cttaagaaaa tcggtagcat ggcccgtcgt gatatcgaac tcatgctagg
    23401 agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct
    23461 agatttggct gactttggct ataatgaaag agaatactaa gtagaggtag gctcatgcct
    23521 gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg aaaccgtttg
    23581 tcgtagctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa ttcgctaccc
    23641 caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc agattatcga
    23701 gtcaatggga cgtcgtggaa aatatttgct tttctgcctg acagacaagg tcttgatttc
    23761 ccatttgcgg atggagggca agtattttta ttatccagac caagtgcctg aacgcaagca
    23821 tgcccatgtt ttcttccggt ttgaagatgg gggcacgctt gtttatgagg atgtacgcaa
    23881 gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta tttctaaaaa
    23941 attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat ctgcccttgc
    24001 caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag ctggacttgg
    24061 caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta gatcttccca
    24121 gactttgaca gcagaagaag cgacagctat tcatgaccaa accattgctg ttttgagcca
    24181 ggctgttgaa aaaggcggtt ccaccattcg gacctatacc aatgcctttg gggaagatgg
    24241 aagcatgcag gattttcatc aggtctatga taagactggt caagaatgtg tacgctgtgg
    24301 taccatcatt gagaaaattc aactaggcgg acgaggcacc cacttttgtc caaactgtca
    24361 aaggagagac tgatgagaaa aatcatcgga atcactgggg gaattgcctc tggtaagtca
    24421 actgtgacaa attttctaag aaagcaaggc tttcaagtag tggatgccga cgcagtcgtc
    24481 caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca ctttgggcaa
    24541 gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct catcttttca
    24601 aatcctgaag agcaaaaatg gtcgaagcaa attcaagggg agattatccg tgaggaactg
    24661 gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga tattccccta
    24721 ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta tgtggaccga
    24781 gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga agctgagtct
    24841 cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca ggttcttgat
    24901 aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga gggaggtagg
    24961 caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg gtaattttct
    25021 gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg aaaatctagg
    25081 tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct ctgctatttc
    25141 cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc gaaaacccat
    25201 gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct ttgtcccaaa
    25261 tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa
    25321 tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac
    25381 tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg gctttatcgc
    25441 agaattattt ggcattcgta cagttttctt actggttggt agttttctat ttttagctgc
    25501 tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg aaaaggctat
    25561 tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca atctcttttt
    25621 aaccagtttt gtcatccaat tttcagctca atcgattggc cctattttgg ctctttatgt
    25681 acgcgactta gggcagatag agaatcttct ttttgtctct ggtttgattg tgtccagtat
    25741 gggcttttcc agcatgatga gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa
    25801 tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc tctgtgccaa
    25861 tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggattgg gaaccggtgc
    25921 cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg gcatttcgag
    25981 ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc ccatggcagg
    26041 ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacga gcctttgtgt
    26101 tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag taaaggaaat
    26161 ctagtgcgag taaaaatcaa tctcaaatgc tcctcttgtg gcagtatcaa ttacctaacc
    26221 agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg tcccaaggaa
    26281 agaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa tagggatttt
    26341 aaggagtttg atatgtataa cctattatta accattttat tagtattatc tgttgtgatt
    26401 gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt tgatgccagt
    26461 tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat gcagcgtttg
    26521 acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt attatcaagt
    26581 agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta aaggatgttt
    26641 gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg aaagatagaa
    26701 taaaagaata tttacaagac aagggaaaga tgactgttaa tgatttggct caggctttgg
    26761 gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta atggaaagaa
    26821 agcaccaaat tcgttttgaa gaagatggta gtctgacatt agaaattaag aaaaaacatg
    26881 agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt gttagtctgg
    26941 aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct attgatggtg
    27001 ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca gcagcagaag
    27061 ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa atcgttctgg
    27121 atcaggaaaa gcctaagtat gctggctata ttcgttcaaa aaatcagaaa atcagtcaac
    27181 cgatttatgt taagaaacca gccctaaagt tagaaggaac agaagttctc aaggtcttta
    27241 tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc gatgtagtgg
    27301 gacactcaac ggatgtcgga attgatgttc ttgaggtctt ggaatcaatg gacattgtat
    27361 ccgagtttcc agaagctgtt gttaaggaag cagaaagtgt gcctgatgct ccgtctcaaa
    27421 aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt gacggtgcgg
    27481 atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc aatctggagc
    27541 ttggggttca catcgcagat gtttcttatt atgtgaccga ggggtctgcc cttgacaagg
    27601 aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca atgcttccag
    27661 aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg acccagtctg
    27721 ctattatgga gattgataaa catggtcgtg tagtcaacta taccattaca caaacagtta
    27781 tcaagaccag ttttcgtatg acctatagcg atgtcaatga tatcctagct ggcgatgaag
    27841 aaaagagaaa agaatatcat aaaattgtat taagtatcga actcatggcc aagcttcatg
    27901 aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc aatgaagcga
    27961 agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag cgtggtattg
    28021 ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc gaacatttca
    28081 gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct gaaaaggttc
    28141 agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatggaact gccagtgaga
    28201 ttagtcagga ggcacttcag gacatcatgc gtgctgttga gggagaacct tatgcagatg
    28261 tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag cacaatcacg
    28321 gccactatgg actagctgct gactattata ctcactttac cagtccaatt cgtcgttatc
    28381 cagaccttct tgttcaccgt atgattcgag attacggctg ttctaaggaa atagcagagc
    28441 attttgaaca agtgattcca gagattacga cccagtcttc caaccgtgaa cgtcgtgcca
    28501 tagaagctga gcgtgaagtc gaagccatga aaaaggctga gtatatggaa gaatacgtgg
    28561 gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt gtcgaattgc
    28621 caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat catttcaatg
    28681 agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg ggtcagcaga
    28741 tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt tcattcgtac
    28801 ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcgtagt ggcagagggc
    28861 gtggttcaaa tcgtcgttcg gataagaagg aagacaagag aaaattagga cgctcaaatg
    28921 ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct ttttacaagg
    28981 aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt cgcacaaaat
    29041 aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat ggtcctgact
    29101 ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg ctttgctcaa
    29161 gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga agagggcaat
    29221 atctggaacc aggaaccaga acgtcgtcgt aaactcctgc ttcataaaaa gcaaattcaa
    29281 aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa ggtctatata
    29341 aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga ctatgacaaa
    29401 cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat gaaagctgtt
    29461 aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa acgcatgcct
    29521 ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac aaaagttggg
    29581 acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt gacagaagaa
    29641 ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat ggcccaacct
    29701 caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt ggaattttat
    29761 tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca ttcagaggtc
    29821 ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttgggttg tggtcagggg
    29881 cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga tcaaaatgga
    29941 ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat gcctgttggc
    30001 ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt ttcaacagtt
    30061 gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat gcaggagaaa
    30121 accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga ttatccttgc
    30181 tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta caaggattgg
    30241 gaattggtta agtacaatga aaatccaggc catttgcacc gtcgcgatga gaatggcaat
    30301 cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac acacatgaag
    30361 attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag gagggaattc
    30421 atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga taaacttgag
    30481 aagcaagcat acacctgccc agcttgtgga ggccagctcc atttgcgtca aggaccaagt
    30541 gtacggacgc attttgccca taaatcctta aaagactgtg attttttctt tgaaaatgaa
    30601 agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa agagacaaag
    30661 gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt tgtaaatggc
    30721 aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa agagcgaagt
    30781 gagggctatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa actgtggctc
    30841 aaggagcgtt tgactcgtct acagcaaggt tttctgtatt tcagtcaaaa catgggcttt
    30901 tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct gatttaccag
    30961 gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca aggtagttta
    31021 ttggaaatat tgcgtcttcc ctataagaga caaaaaatat ctcattttac agtttctgag
    31081 gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct cttttggatg
    31141 aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg actgaaagaa
    31201 tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca agacttgact
    31261 agctattatc agcactttta tacctattac caaaaaaatc ctcaaaatga ttggcaaaag
    31321 ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga atagaaagga
    31381 tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac atgggatata
    31441 tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt aacagaacaa
    31501 ttggagacag tagcccagta tgaaggccat ctcttggata gtgcggataa cctactagaa
    31561 atcactgaat tttctcttga aatggaacgc cagatagaga agctttacgt ttatgctcat
    31621 atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc caaggtcatg
    31681 acactctaca gccagttaga ccaagccttt tcattctatg agcctgaatt tatggagatt
    31741 agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt ttatcaacac
    31801 tattttgaca agctcttgca aggcaaggat cacgttcttt cacaacgtga agaagaatta
    31861 ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat cttggacaat
    31921 gcggatattg tgttccctta tgtcctagac gatgatggta aagaagttca gctatctcat
    31981 gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg tgcctatcaa
    32041 gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacctt gcaaaccaat
    32101 gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg tcatgcagcc
    32161 ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc agttcgcaag
    32221 catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg gatttcagat
    32281 ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacagttt tacctaccaa
    32341 gaagccttga aaaaagcaga agatgctttg gcagtcttgg gtgaggatta cttgagccgt
    32401 gttaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg caagcgttca
    32461 ggtgcctact ctggtggttc ttacgatacc aatgccttta tgcttctcaa ctggcaggac
    32521 aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca ttcaagctat
    32581 actcgtgaaa ctcagcctta tgtttacgga gattactcta tctttttggc tgagattgcc
    32641 tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga agacgacgca
    32701 acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt tttccgccaa
    32761 actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg ggaggtcttg
    32821 acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta tggtttgagt
    32881 aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt ctactataac
    32941 tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc tgaaaaaatt
    33001 gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc aggtaagtcg
    33061 gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga agactacctc
    33121 aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct tgttgaaaaa
    33181 ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata acatgcgtcg
    33241 tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc aggtcacagg
    33301 tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta ttccccatga
    33361 aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata ttctggaaat
    33421 tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa aggctaagat
    33481 tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt ttgcccagtt
    33541 tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gtggatgtct tatctacact
    33601 gacagagtct tatgatttcg tatttatgga ttctgccaag tctaaataca tcgtctttct
    33661 gccagaaatc ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg atatttttca
    33721 aggtggtgat gttgccaagg atattatgga agtccgtcgt ggtcagcgaa ccatttatcg
    33781 aggccttcaa aaattatttg atgcaacctt agacaatcca gaactcaccg caacattagt
    33841 gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc aactgtctga
    33901 aagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga gtaacactta
    33961 tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac tattatcagt
    34021 agcaacttta gcagcttgtt cgaaagggtc agaaggagca gaccttatca gcatgaaagg
    34081 ggatgtcatc acagaacatc aattttatga gcaagtgaaa aacaaccctt cagcccaaca
    34141 agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct cagagcttga
    34201 tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg aaaactacca
    34261 acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa ttcgtacaag
    34321 taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag atgaagccta
    34381 taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc gtcttaataa
    34441 tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg attttgctca
    34501 attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag aaattacctt
    34561 tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg ctttagatgt
    34621 ggatggtgtt tctgatgtga ttacagcaac tggcacacaa gcctacagta gccaatatta
    34681 cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact acaaagaaaa
    34741 attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc aaagcattat
    34801 cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc aaaatatctt
    34861 tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa acgaatagtc
    34921 caaatcaatg agtcagggaa aaaaactcga cttcaggaaa aaatgaagca aacattccca
    34981 caataaaacg catagtacaa ggtttgtact gaccccaaaa gttagacaat taatttatct
    35041 gaaggattta gttctgtatt gcacagggct aagtcctttt agttttacct taattctctt
    35101 attgttgtaa taatcaatat agtctataat ggcttgttcc aattgattaa gtaatttaaa
    35161 tgttttctca tagccataaa acatttcgga ttttaaaatg ccaaagaaag attccatcct
    35221 accgttgtct tggctgtttc ctttgcgtga catagatgct tgaattccct tactctctag
    35281 gaagcgatga taagaatcgt gttggtattg ccagccttgg tcactatgga gaatcgtatt
    35341 ctcgtagtgc ttctctttga atgcctgttc caacattaac gatcaatcaa tttaa
//
LOCUS       DAVLUM010000015        34616 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLUM010000015 DAVLUM010000000
VERSION     DAVLUM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.015"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(195..759)
                     /locus_tag="VYN42_000593"
                     /pseudo
     CDS             complement(195..759)
                     /locus_tag="VYN42_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(835..1062)
                     /locus_tag="VYN42_000594"
     CDS             complement(835..1062)
                     /locus_tag="VYN42_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1461714.1"
                     /translation="MRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            1090..1398
                     /locus_tag="VYN42_000595"
                     /pseudo
     CDS             1090..1398
                     /locus_tag="VYN42_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1553..1876)
                     /gene="tnpB"
                     /locus_tag="VYN42_000596"
     CDS             complement(1553..1876)
                     /gene="tnpB"
                     /locus_tag="VYN42_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1461715.1"
                     /translation="MTIHLSSLGQVYLVCGKTGMRQGIDSLAYLVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(1857..2042)
                     /locus_tag="VYN42_000597"
     CDS             complement(1857..2042)
                     /locus_tag="VYN42_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461716.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2346..3908)
                     /gene="guaA"
                     /locus_tag="VYN42_000598"
     CDS             complement(2346..3908)
                     /gene="guaA"
                     /locus_tag="VYN42_000598"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1461717.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4050..4748
                     /locus_tag="VYN42_000599"
     CDS             4050..4748
                     /locus_tag="VYN42_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1461718.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4791..5687)
                     /locus_tag="VYN42_000600"
     CDS             complement(4791..5687)
                     /locus_tag="VYN42_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1461719.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5696..6631)
                     /locus_tag="VYN42_000601"
     CDS             complement(5696..6631)
                     /locus_tag="VYN42_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1461720.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRVLLTAPELKEVMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6628..7353)
                     /locus_tag="VYN42_000602"
     CDS             complement(6628..7353)
                     /locus_tag="VYN42_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1461721.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7437..8072)
                     /locus_tag="VYN42_000603"
     CDS             complement(7437..8072)
                     /locus_tag="VYN42_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1461722.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTLKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKAYLY"
     gene            complement(8074..8901)
                     /locus_tag="VYN42_000604"
     CDS             complement(8074..8901)
                     /locus_tag="VYN42_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1461723.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MTFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8923..9259)
                     /locus_tag="VYN42_000605"
                     /pseudo
     CDS             complement(8923..9259)
                     /locus_tag="VYN42_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(9260..9976)
                     /locus_tag="VYN42_000606"
     CDS             complement(9260..9976)
                     /locus_tag="VYN42_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV1461724.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGIAPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            10489..11100
                     /locus_tag="VYN42_000607"
     CDS             10489..11100
                     /locus_tag="VYN42_000607"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1461725.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11145..11873
                     /gene="rlmB"
                     /locus_tag="VYN42_000608"
     CDS             11145..11873
                     /gene="rlmB"
                     /locus_tag="VYN42_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1461726.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(11911..12822)
                     /gene="trxB"
                     /locus_tag="VYN42_000609"
     CDS             complement(11911..12822)
                     /gene="trxB"
                     /locus_tag="VYN42_000609"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1461727.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12888..13112)
                     /locus_tag="VYN42_000610"
     CDS             complement(12888..13112)
                     /locus_tag="VYN42_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1461728.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13190..13933)
                     /locus_tag="VYN42_000611"
     CDS             complement(13190..13933)
                     /locus_tag="VYN42_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1461729.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMPFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFTSYKRTYI"
     gene            complement(13933..14733)
                     /locus_tag="VYN42_000612"
     CDS             complement(13933..14733)
                     /locus_tag="VYN42_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1461730.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14891..15247)
                     /locus_tag="VYN42_000613"
     CDS             complement(14891..15247)
                     /locus_tag="VYN42_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1461731.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15241..15771)
                     /locus_tag="VYN42_000614"
     CDS             complement(15241..15771)
                     /locus_tag="VYN42_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1461732.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(15771..16265)
                     /locus_tag="VYN42_000615"
     CDS             complement(15771..16265)
                     /locus_tag="VYN42_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461733.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16400..16846
                     /locus_tag="VYN42_000616"
     CDS             16400..16846
                     /locus_tag="VYN42_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1461734.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTIKLYHQTLDLIDHTQEEVIQ"
     gene            16843..17490
                     /locus_tag="VYN42_000617"
     CDS             16843..17490
                     /locus_tag="VYN42_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1461735.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17511..18092)
                     /gene="pdxT"
                     /locus_tag="VYN42_000618"
     CDS             complement(17511..18092)
                     /gene="pdxT"
                     /locus_tag="VYN42_000618"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1461736.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18093..18968)
                     /gene="pdxS"
                     /locus_tag="VYN42_000619"
     CDS             complement(18093..18968)
                     /gene="pdxS"
                     /locus_tag="VYN42_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1461737.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19120..20499)
                     /locus_tag="VYN42_000620"
     CDS             complement(19120..20499)
                     /locus_tag="VYN42_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1461738.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20793..21716
                     /locus_tag="VYN42_000621"
     CDS             20793..21716
                     /locus_tag="VYN42_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1461739.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21776..22381
                     /locus_tag="VYN42_000622"
     CDS             21776..22381
                     /locus_tag="VYN42_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1461740.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22399..23643
                     /locus_tag="VYN42_000623"
     CDS             22399..23643
                     /locus_tag="VYN42_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1461741.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGDHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23866..24123)
                     /locus_tag="VYN42_000624"
     CDS             complement(23866..24123)
                     /locus_tag="VYN42_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1461742.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24165..26201)
                     /locus_tag="VYN42_000625"
     CDS             complement(24165..26201)
                     /locus_tag="VYN42_000625"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1461743.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26461..27378)
                     /gene="glyQ"
                     /locus_tag="VYN42_000626"
     CDS             complement(26461..27378)
                     /gene="glyQ"
                     /locus_tag="VYN42_000626"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1461744.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27397..28158)
                     /locus_tag="VYN42_000627"
     CDS             complement(27397..28158)
                     /locus_tag="VYN42_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1461745.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28431..29273)
                     /locus_tag="VYN42_000628"
     CDS             complement(28431..29273)
                     /locus_tag="VYN42_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1461746.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29387..30778)
                     /locus_tag="VYN42_000629"
     CDS             complement(29387..30778)
                     /locus_tag="VYN42_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1461747.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31013..31390)
                     /locus_tag="VYN42_000630"
                     /pseudo
     CDS             complement(31013..31390)
                     /locus_tag="VYN42_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            31605..32582
                     /locus_tag="VYN42_000631"
     CDS             31605..32582
                     /locus_tag="VYN42_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1461748.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQIPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32579..33661
                     /locus_tag="VYN42_000632"
     CDS             32579..33661
                     /locus_tag="VYN42_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1461749.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33725..34616)
                     /locus_tag="VYN42_000633"
                     /pseudo
     CDS             complement(33725..34616)
                     /locus_tag="VYN42_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10302 a         7717 c         6235 g        10362 t
ORIGIN      
        1 ggtaaatagg cctctaaaac ctctttgttt acgagagttt ccacgtttgg aagacattct
       61 agaagatagg atagatattt ctcactattt ataatggatt gaaataagat atgaacaaat
      121 cgattaggaa aggaaaattg atttatagaa atgttttagc agtcgatgcg tactgttata
      181 gattcaacgc actataattg atgacgttta gctgtttcca acaaactcat aataatagct
      241 cttgctttag ctccttcaaa actttgagaa aataaccacc ctcgcttttt taaactgagc
      301 ttaggctaaa agagtccact ggactctttt actccgtccc ataaccaatg atttaatggc
      361 gcattcagct agattattgg aaaggaccag atgtccgtct ttcaaaatag tcttaaaggt
      421 ttctttatac ttgaggctat acttgaggct gtattcaatt gcccttccta gttttgaacc
      481 cgataaaact gactgacgcc ggcaccaagc aaagaagtct tccattaggg gctggagatg
      541 ttcttgacgt ttctgtagtc gttcatcagc tggcaaagcc tcccagtctc tttccaagga
      601 aaataactga tcacaataag ctaaaccttt agctcctaag gatgatttat ctgcttgctt
      661 gggggtcgct tcaaaaaatt tccttctcac atgcgcccaa catccaacaa gtgcagcttc
      721 ttccagttga cgataagctt ctagcggttc gcagtttacc aagcttagcg tcgccttgct
      781 cctaaacctt ggactgctat cgcataggca gaactagagg actaaagtcc taagttactg
      841 ccgcaacata tcacaatgaa catagccaga ataatctcct aggaattctt gtactactga
      901 accacttcga cactgatcat ggtggtaaag cgtaatccct tgtttctctg atttacctga
      961 caaaaaagtc caatagtaag tcagctgact atcactttct aagacccgat aagaggtttc
     1021 atctgcatga agtaagggct gagtcaatag tctctctcgc aagaggttat aaagaggctt
     1081 taggaatagg agctttcaca agcttatcca gatgattatc ttttactcgt tatggacaat
     1141 gctatatggc ataaatcaag tatcttaaag attccgacta atattggttt tacctttatt
     1201 cctccataca caccagagat gaaccccatt gaacaagtgt ggaaagagat tcgtaaacgt
     1261 ggatttaaga ataaagcctt tcgaactttg gaagatgtca tgaatcaact tcaagatgtt
     1321 atacaaggac tggagaagga ggtgataaag tccatcgtta atcggagatg gactagaatg
     1381 ctttttgaaa gcagatgagt ataaaaagaa agtcctcatt tcaatagaaa tcacgacttt
     1441 ctgatggatt tatagtaaaa tgaaataaga acaggacaaa tcgatcagga cagtcaaatc
     1501 gatttctaac aatgttttag aagtaaaggt gtactattct agtttcaatc tactatattt
     1561 ttggagtgat agaaaaacct ttcatcagcc aatctacttg ttcaggtgcg agagctttga
     1621 catccttttc tgtactgggc caagtcagtc tgccgttctc aaagcgttta tataatagcc
     1681 aaaatccttg accatcccag taaaggactt taaagcggtc tttacgtcca ccacaaaaga
     1741 gaaaaacttg acctgagaaa gaatccaatt caaagtgggt tttaaccaga taagccagtg
     1801 aatcgattcc ttgtctcata cccgttttcc cacatacgag atagacctgc cctaggctag
     1861 atagatgaat tgtcatagag caacacctta tccaaaagct gttctatcat ttcgagattg
     1921 agagattgaa aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag aatatcattt
     1981 ctctttttag aatcaaaacg acgagattgt ggaatctcta caggaacaat aggttgtggc
     2041 attaaaatat cctccaatag ttttacttta ctaatagtat acaggaggag ctccatgaat
     2101 gatagatacc ttgttatgac gcgcttacca tattagaaag ttggctctct aattaaatta
     2161 attctcatta tatatatcaa aagaccgcag cttgaaaact acggtctaat tttttgtcca
     2221 aatgtaaacc acttggaact attattcaat ttattctttt tagcaaatgt tcccgtttta
     2281 atcccagtta cagtttttaa tcctctgtaa ccgttgattt tacaaagctt ttaatttttt
     2341 tgcgattatt cccactcaac tgttgcaggt ggtttacttg taatatcgta gacgatacgg
     2401 ttaacatgat ccacttcatt tacgatacgt actgagattt tttgaagtac ttcccatgga
     2461 attttggcaa aatcagcagt cataccatcg atagaagtga tagcacggat tgcaatcgtg
     2521 tagtcatacg tacgaccgtc acccataaca ccgactgagc gaacgcctgt gttaacagtg
     2581 aagtattgcc aaatatcgcg gtcaagtcca gctttagcga tttcttcacg aagaatagcg
     2641 tctgattcac gaacggtttc aagtttctct tcagtgattt cacccatgac acggatagca
     2701 agtcctggtc ctgggaatgg ttggcgccat acgatgtggt ctggcatacc aagctctgta
     2761 ccaagagcac gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa ttcaaactgc
     2821 atatcttctg gaagaccacc cacgttgtgg tgtgacttga tagtttgagc tgtatccgta
     2881 ccagactcga taacatctgt atataaagta ccttgagcaa ggaatttcac atctttgagc
     2941 ttgcttgctt cgtcatcgaa tacatagaca aactcgttac cgatgatttt acgtttttgt
     3001 tcaggatcag aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc tgctttgacg
     3061 atattcaaac caaacttacc accgagcatg tccataactt gatcagcttc gcctttacga
     3121 agaagaccgt ggtctacgaa gatacagatc aattgatcgc caatcgcttt ttggagaaga
     3181 accccaacga cagatgagtc aacaccacct gatagaccaa gaaggacacg tttatcaccg
     3241 acggtttcac gaattttttt gatctgcata tcaatgaaat tatccattga ccagtcacct
     3301 ttagccttac aaatgttaag ggcaaagtta cgaaggatat catttccgta tacagaatga
     3361 cgaacttctg ggtggaattg gataccgtaa atgtgtttat ctgggttttc gatggctgcg
     3421 tatgggcagt cagctgatgt acctgtacga acaaagtcag caggaatctc agtaaccgca
     3481 tcaccatggc tcatcaaaac agtctgttca tcaggtgttg attcaaaaag cgctgatggt
     3541 gtgtgagtta gggttgattg accgtattca cgatttccag catcacctgc aggaacaact
     3601 tttcctccaa gtttatgggt caataactgc ataccataac agattcccaa aattggaatt
     3661 cctagttcga agatttctgg gtcaatgtca aatgaaccat cttcatatac agaatttgga
     3721 ccacctgata gaataattcc tacaggattg acttcacgaa cttcagcagc tgaaatttta
     3781 tggcttttta gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat cagctggttg
     3841 tactggctac catagtccaa tacgatgatt ttttctacat cttgcaaatc agttgaaatg
     3901 ttgctcatct ttttcctttc tcaaaagaaa tatcttttct caatattcta tcacaaataa
     3961 gggcgaatta ccaactaaac aaggcgaagt ttgacttttt ctagtttatt ggggtacaat
     4021 agagaaaaga tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa atccatgatc
     4081 agataaaaaa ggatattgac gagcaccgtt gggctattgg tgagaggctt cccagtgaaa
     4141 gagatttagc tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc gtatctctat
     4201 tagtcgaaga aggcgtctta gagcgccgtg taggaagcgg cacctttgtt tccagtactc
     4261 gagtacaaga aaagatgcga gggacaacca gttttactga aattgtcaaa tcccaaggta
     4321 aagttccctc tagccagctc atttcctaca aaaaaaccat tcccaatgag caagaagttg
     4381 ccaagctagg aatttttcca acggacaata ttatccgaat ggagcgggtc cgctatgccg
     4441 accaagttcc cctagtttat gaagttgctt ctattcctga aaaattcatt aaggacttta
     4501 aaaaagaaga aatcaccagt catttcttcc aaaccttgca aaaatatggc tatcgtatcg
     4561 gcaaatctca acagaccatc tatgctcgcc ttgctaaaga aaagattgcc cactatttgg
     4621 aagttgaaaa aggacatgct attcttggat tgacccaggt ttcctaccta gaagatggta
     4681 ctgcttttga atacgtaaaa agtcaatatg taggcgaacg ctttgaattt tatcttgaaa
     4741 ataattagat taccacgcaa aaactctctg tcacagacaa agagtctttt ttatttttct
     4801 aagaataaat ctttcaaaga aatcaaagtt acagcaaaca atatcattgc cataccaata
     4861 aaatcaatgg gataaaattg ttcattcatt attaagaagg caaagaaaac cgccgatatt
     4921 ggctcaattg aagccaacaa gcttgacttg accggtccta tcagactggc tcctttaagg
     4981 aaagctgtat aggcaaagac agtcccgata aggataatgc ctgcaaacgc aaggagaaaa
     5041 tcaagactag tcgggatatc ggcctgtaga acccctgtaa aaggaagggc gaccaaacct
     5101 gctatgacca ttcccacacc aatgaccaag ctgctccccc actttttaat caaggctatg
     5161 ggtaaaatga tatacagagc ataagtcaag gcagaaaaga gaccccagaa caggccagca
     5221 ggtgtcatgg ataactggtc caactgccca tgtgttgcga tcaggaaggt tcctccgatg
     5281 gcgaatatga tggaaactat ctctcccagt gtcggtgcca ccctatcctt gatacagcta
     5341 taaattaaaa ttccgacagg acaaacatac tgaagcaccg tcgctgttcc cgcattggtc
     5401 tcctgaatag cagacagata ggcgaattgg ttgagaaaaa gaccaatcag agcaaaaata
     5461 agaagagaca gcaaactctt tctatccttt aaaaagacca gtattttatc ctttgcagta
     5521 gcataagcca agagcatgag aattccacca gcgattaaaa gacgcaagtt ggttaagacc
     5581 agagccgaaa ttccgtgtgc catcaggtat tggccactcg ttcctgacaa cccccaagca
     5641 ataccagcca caactgttag taaagtccct tttaaactat ttgacatgtc tctccttact
     5701 cttctttgcg aatcaagttc atcacttgat tgcggtctaa tatccattga gctctctcgt
     5761 ccttttcata ggtacgattc gataggaaaa tagtggcttc ttgcttctga cgattccaca
     5821 tgataaaggt acctgtatag cccgtatggt ctagccaatc tccttccaaa ttccatgcta
     5881 aagaacgttc cttgtcatcc aaaggagaaa aattttgatt taagtctctt gcaaaatcat
     5941 ctgctaaata gtgttctaaa aaggtttgta aatcctttat agtcgaaaat aaaccagcac
     6001 tcccagcatg tctacccagg agacgagcct tgggatcatg cactatgcct gcctctacac
     6061 ctctaactgt tggaacagca agctcaactg gcccaaactt agtttccgtc attccccaag
     6121 gtttccagac ttgatccttt aaaatcacat ccaaatcttg attaaaaatt ctttccaaaa
     6181 taaagcccaa cagcaaaaaa tggacatccg aataaagaaa ggctggctga cttcgtctgt
     6241 tgagatgaaa catcacttcc tttaattcag gggctgttaa aagaacacga ttaggaataa
     6301 aaggatcaag gtctgttgca tgagtcaaga gctggcgaat agtgatgtct ggataatcac
     6361 tctcaggtaa aaaatctatt accagtctat caatatctaa ttgacctatt tcccacaaga
     6421 aggtacaaac tgtgccaacc ccaacaacct tgctgacact agctagatca taaactagtc
     6481 ctgcctcagt ctgcaagcca tgctctgggt cactctggcc taaatagaac tctgtccatt
     6541 gattgtcctt aaaatacgca aaagaggctc cgggataaat tcctgcctcg atttgttctt
     6601 ctattttttt aataatcttg gtccacttca tacttcttca aaccacaatt caacattatt
     6661 tctatcttta caaaggaaga atttttcaga cttaggaata aaatattcag tagactcaaa
     6721 cttctggcga agacttgcta tgtctaattc attgaccaag aacttgagca tagataagtc
     6781 ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga gctggaataa aatcaaggga
     6841 tgccccaatt tcagatgatt ccaagaaact ttcgatatca gttgggagat gtaattccat
     6901 agaaatctca aatttactta aagaaattga tgccaaatct gtttgaaatt caggcttttc
     6961 tcctacttct actagacttg ctctgtcatc ttccgcatga atcaaaatca aatcatcttc
     7021 tggtgagaaa atttcaaaag cgtagccatt ttgaccttta tataatcgat gaatcgaatc
     7081 tgttttagat aagattcctt caatttctaa gggattttcc accttgacaa tcaatctagc
     7141 tagttttttt cttccctcta ccttacgagt acgcatactg ggagcttctt ctaaaaccag
     7201 cttttcaaga cccgtttggt cacctagtga cagaaaggcc gattcttcta acaaggcctt
     7261 cattccaagg gtttcaatat aaaatgtttc atttagtttt ctattattag cttttaaagt
     7321 aggaataatc cgtacaatct gatttacatt cataaattcc tccgtcactt tttattttaa
     7381 aggattttag aattttttac aagatattat gctcaaattt aacattattt agctatttag
     7441 taaagatagg ctttcaagga ttttgacaaa gcctgataac cagcaatact gaggtgcagt
     7501 ccatcagttg tatattcttt tttgagttgg cctgcttggt ctgtcaaaca atcaaatact
     7561 ggcacaaatt ccacctgcat ataggcagat gcaagctctt gataggcttg attccagttc
     7621 tgaatttttt cattcgagcg gatatagact gcctgctggt actcctctcc ctcattgaca
     7681 ggcaaaatgg aaagcaattt aatctctgtc aatggataat cgcgagcaac ggattgaatg
     7741 atagcttcga gattattgag agcctcattc acaggaacat cctttccgat atcatttgtc
     7801 ccaatcagaa gaaaaatttt atctactgct ccaccatata gatgagcatc aaggttctct
     7861 agtaacagtc ctgtctgata gccacgaatt cctcgattga caatcgtctt taaagttcca
     7921 aatagctcct gtagaggata atactcgaca atggaatccc caataaaaag aatgtttggt
     7981 tctacaacag aaatgtgatt taggtgacga tatttggttt gaattttttc ttgttccttt
     8041 aggagccaat tttctaataa ctgtactgcc acttcattct cctttttcta accagttttc
     8101 caagacttga taaactcctc cttggctgtt ggctggtgct agagcagtcg ccacagcttt
     8161 ggctttctca tcagcatttt ccatcgcata ggcaattcca gccatttcaa gcatttcaac
     8221 atcattttca ctatcaccaa aagtcatgat ttcttgggat ttcaagtccc agcgcttgag
     8281 taattcctcc aagccccatg ctttatgaat cccagcttgg aggatatcaa tgcaaccata
     8341 gccactggat acagctcgga cacggccatc aaagagagca ttgatttctt ccaaaaccga
     8401 actcaaacgt tcctcaccaa caaccatgct catcttgagc acaccaccaa agagatcaga
     8461 tgttaattca tccacaaatt gcatccgttg gtagaatttt tcaatcattt ctggagtcat
     8521 aaaactttca agatctgtaa aaatcgtacc ttccttgaca aaatcaccct tcatccccgt
     8581 tacaacaaac tggtcctgac acgctcggcc cttgaaatga gccaaagcct tgttgacaat
     8641 ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt tcaaaaatac gagcgccatt
     8701 agcaacaacc agaaccactc gatccaccaa gggactcagt agttgtctca tgcggtgaat
     8761 ttcattgccc gtcgcaatga caaaacgaat gcccctttga tccaactgat ctaaaatctt
     8821 ttccaatcgt gggagatcaa gctgacctct agcatccagc aaggtcccat ccatatctgt
     8881 cgcaattacc ttaatcatca tttactttcc tctggattca agctaatacc acttcaatcc
     8941 cacatgttca ttcatttctt tataggctgt atcaattcgt tccttagtcg cttcatctaa
     9001 ctggtcacga tgactgccac ccctctataa aatcttccaa aatataagtt tgataatgat
     9061 acaagggata tccttctggt gaaaaggttc cctttggtgt tcgattgacc caagtaggat
     9121 gagctttagc tgttccgata gttgtttttc catccttctt cttgatggtg acatccatga
     9181 gaacaccacg ttcagtccac ttagcattct cttcatctcc catagattca attcgttgat
     9241 tggaaatgaa gttccccatt taatagacaa tgagcttctt atctccatct ttttccaccg
     9301 tttcagatgg ttcaacaacg tgaggatgcc ctccaaagat aatatccgct ccccaatcga
     9361 tcatcttgtg ataaagagct ttttgttctt cagttggttc caatcgatac tcaacaccca
     9421 tctgaggcat gataatggtg atatctgctt ccttctctgc ccgttcaact tcagccttta
     9481 tcttatcttc gtttaaatct gaaagataac gattatagtc ttcctgagaa atatactgct
     9541 caattccatt gaaaccatag gaataggcta acaatgcaac cttgatagca ttcacttcct
     9601 taatgaccag cggagcctga tcacgtggtt cgtgcgtata aactccgatt ggagcgattc
     9661 cagctttctc aataatatcg gccattgaaa taactccctc aatttgcgaa tccaaaatat
     9721 gattatgagc taaatccagc acatgataac ctgcctcctt aatagcatcc ataacttcaa
     9781 caggagcatt aaagagaaga taacccgcta aataatgatc cttattaatg gttccttcaa
     9841 aatcaccaat agctaaatct gcttgcttga gccaaggagt cacatactca aaattttcat
     9901 gaaagtcata ggtaccgtct tcttttttag ctgaaaagaa aagtccatcg tggtagagca
     9961 aatccccgtg ggccataatt ctggcagttt tttcctcttc ctactcctga gacttttgct
    10021 tagtcccctc ttgagaaata gtatctcgtt tttgactagt caagggattc cttggaagct
    10081 ttcaaacaac aagaccaagc ccattgataa accaactgct agcaagagta tcgccacaaa
    10141 tcccttattg ctccacttgc gataactcct aaaaagttta ccaagccctt cataaaacga
    10201 aaagctaaac caccctgatt tcgattttgt cttctttgta tcttcgttct ccctactttc
    10261 ttatgcaagc cttttctttt tattatatca cagataagta tttctttcac aattgaattg
    10321 aacttcctat ctattttcta taaatcctaa atgccataat gctttcaatt cttgtcattt
    10381 tgtgatatca tgtagaggaa atgaactaat ccacagtggc ttattccaag tataccactt
    10441 gggctttggc agtagctaac tgcactaaac ataatataag gagagaaaat gtctgcaata
    10501 gaacgtatta caaaagctgc tcacttaatt gatatgaacg atattatccg tgaagggaat
    10561 cctactctac gcacggttgc tgaggaagtc actttccccc tatctgacca ggaaatcatc
    10621 ctaggcgaaa agatgatgca attccttaaa cattcccaag atcctgtcat ggctgaaaaa
    10681 atgggactcc gcggtggtgt tggactggct gctccccagt tagatatctc aaaacgcatt
    10741 atcgctgttt tggtacctaa tattgttgaa gaaggcgaaa ctccacagga agcctacgat
    10801 ttggaagcca ttatgtacaa tccaaaaatc gtctctcact ctgttcaaga tgctgctctt
    10861 ggcgaaggag aaggttgcct gtctgttgac cgtaacgtgc ctggctatgt tgttcgccat
    10921 gcccgcgtta ctgttgacta ctttgacaaa gatggagaaa aacaccgtat caaactcaaa
    10981 ggctacaact ccattgttgt tcagcatgaa attgaccaca ttaacggtat catgttttac
    11041 gatcgcatca atgaaaaaga cccatttgca gttaaagatg gtttactgat tcttgaataa
    11101 agaaaatccc gttgcaagac ggggttttgt gttataatag aggcatgaaa acaaatgata
    11161 ttgtctatgg tgtccacgcc gttaccgaag ccctccttgc aaatacagga aacaaactct
    11221 acctccaaga agatctccga ggtaagaatg ttgagaaagt caaggaacta gctacagaaa
    11281 agaaggtgtc catttcttgg acatcaaaaa aatctctctc tgagatgact gaaggtgctg
    11341 ttcatcaagg ttttgttcta cgagtgtctg aatttgccta tagcgagcta gattacatcc
    11401 ttgcaaaaac acgccaagaa gaaaatccac ttctattgat tctagatggt ctaactgatc
    11461 cccataatct gggttctatc ttgcgaacag ccgatgcgac caatgtttca ggtgtcatca
    11521 ttcccaagca ccgtgctgtc ggagtaactc ctgtcgttgc caaaacagcc acaggtgcta
    11581 ttgaacacgt tccaattgcc cgagtgacaa acctcagtca aaccttagat aaactcaagg
    11641 atgaaggctt ctggaccttt ggaacggata tgaacggtac tccttgccac aagtggaata
    11701 caaaagggaa aatcgccctc atcattggaa atgaaggaaa aggtatctct agcaacatca
    11761 aaaaacaagt cgatgagatg attaccattc cgatgaatgg acatgttcaa agccttaatg
    11821 ccagtgttgc tgcggccatt ctcatgtacg aagttttccg aaatagacta taaaaagttt
    11881 ccagtcatct gattggaaac ttttttataa ttaactatgt tctgtaatga atttataggc
    11941 ttcttgacca gcgatagctc catctccaac cgctgttgtt acttggcgaa ggtctttcaa
    12001 gcgaacatct ccaactgcaa agataccgtc gactgcagtc ttcatgtggc tatctgtcac
    12061 aatccagcct gcctgatctt ggatattcaa ttctttaaca aaatcgctaa gagggtccaa
    12121 tccaacatag ataaagacac caccgaagac ttgttctgtc acttgacctg ttttcacatt
    12181 ttcaaatacg actgattcta ctcggttttc acccttgatt tcccttacta cagaatccca
    12241 gataaagctg attttttcat tcgcaaaggc gcgatcttgt aaaacctttt gggcacgaag
    12301 ttggtcacga cggtgaacaa tggtaacagt cttagcaaaa cgagtcaaga agagggcttc
    12361 ttcaacagct gaatctccac caccaactac caataaatct tggtcacgga agaaagcacc
    12421 atcacacaca gcacagtaag aaacaccacg actgttcagt tcttcttctc caggtactcc
    12481 caaaggacgg tgtttagaac cagttgctac gataactgta cgtgtttcat atgtttggtc
    12541 atcagtcatc actttcttaa aatcaccatg gtcttcgaca ttttcaacat aaccataaat
    12601 gtgctcaaca ccaagatttt caagtggttc aaacatcttt tcagccaatt caggtccact
    12661 aatattagcg tatcctgggt aattttcgat atcagatgta ttattcatct gaccacctgg
    12721 cagaccacct tcaatcaaag ctacttttag attgcttcga gcagcataca aggccgcagt
    12781 catccctgca ggtccagcac cgataataat agtatcgtac atatagattc cttctttctt
    12841 gttgtaacta tctttattct aactctttct tgtcaatcac gcaaggatta tgccttgaaa
    12901 acaagaatta aactcataac cgcaaaggat aatactggga caaccaagac tccaatcata
    12961 atcatatcat agagatgggc ttggcgagcc ttggctgtct tatcaactcc cgacatggct
    13021 ctcagaccaa tccaaatccc taaaaaaatc agaacaagga tggtggtcaa gatcaaactc
    13081 tcgaaatata aagaaaatag ttgcagtagc atgatttctc tcatttctat cttttttaaa
    13141 gagtaaactc agctagtcca actaactgag ttttccttta tctattatat caaatataag
    13201 tccgtttgta actagtgaag aattcttttg tccgctcttc tttaggggtg tggataatct
    13261 catccggagt tccagactcg atgattttcc ccttatctaa gaagagaatt ttatccgcaa
    13321 cttgggctac aaagggcatg tcatgactga ccaaaatcat ggtctgacct gacttagcag
    13381 catctgcaat agacttttct acttcaccga ccaattctgg gtcaagggct gaagttggtt
    13441 cgtctaagag caaaacatct ggtttcatag caagcgcacg cgctagggca acccgttgct
    13501 tctgtccacc tgataaatgg cgaggataat ggttttcacg gtccgaaagc ccaaccttag
    13561 ccaactcttc cttggcaatc ttagtcgctt cttggtcaga taatttcttg acaacaacca
    13621 agccttcttt cacattatca agtgctgttc ggcgttcaaa taaattaaac tgttggaaaa
    13681 ccatagacaa cttacggcgt agggcaagga tttcttcttg agtgatttta gaaaaatcaa
    13741 ctgaaaaacc atcaatctga atagagccac tgtcaggtgt ttcaagataa ttgagactgc
    13801 gaagaaaggt tgattttcca gctcctgaag aaccaatcaa ggctacaact tccccttttt
    13861 gaatatccaa gttcagatga tccaagacag tctgtcctga aaaggatttg cttaaattcg
    13921 aaatcttaat cattaacgaa ggtctccttt cacatctgtt tgcactgtat caggtgcaga
    13981 aatagccatt tttctctcga tgaaacgacc gaggctttca attccgatat tgactaccca
    14041 ataaacaagg gcaacggaga tgaagcgttc aaaatagcga taatcagctc cacctagaat
    14101 ctgagcttgg gcaaagactt ccacaacacc cgcactaaaa gctagagatg ttcccttggt
    14161 caaaccgatg agggaattaa tcaaggttgg agtagctacc accgctgcat taggaataat
    14221 cactcgtcga taaacttgcg ctcgggtcat acccagactg cgtgccgcct caatctcacc
    14281 aggattaact gagagaatgg ctgcacgaat ggtttcacta gcataagctg cctcattaaa
    14341 ggcaaaggcg acaatcgcaa aagctgcagc tggaatcgca ttgatattga gaccagttcc
    14401 ccattgctga ttgagggctt tcaaagccaa aggaattccg tagtaggtca acatgagttg
    14461 caccaaaatc ggtgtccctt ttaagaaact aacaaagaag gcctgcaagg gatataaaat
    14521 cttgacacga ttgatcttca caatggcaaa aagaagcgcc aaaaccaagc caaaaagggc
    14581 accaccaatt gtcaacataa ttgttgttgg aagttgttgg acaattctag ggattccatc
    14641 aaagaccgaa cgtaggctaa acagcttgcc atccggaatc aattgcatca agttttggta
    14701 ccaatctgat gctaaaatcg ttgtaacatt cataaaaaca tcctcttctg ataatgattc
    14761 attctaccat gcttctgccg tcaatgaaat tatttgctac ggtcagatac agactttgtc
    14821 tacctactag tttatcatac tttgaaacag ggaagttata tattttatct atcaaagaga
    14881 tagataaaaa ctatttcagt cccagttctt cataagattt tcgataaccg atttgcttaa
    14941 cagttccatt ttctactaaa atgggccgtt ttaacaacat accgtcactt gctagcaact
    15001 cagccgcttc ttggtttgac aaacttccta ccttatcttt tagccctaat tcacggtatt
    15061 tgataccact ggtgttgaaa aattgcttca attcaaatcc tgaggtttct agccaattca
    15121 aaatgacttc ttggctaggt gtttcttcca cgatatggac ggctttatag tccacaccta
    15181 attgatttaa ttcttgtttt gcttttttac aagttgaaca tttggggtat tcgataaatt
    15241 ctaacatgtg cttctccttc tattgcttct atctttaaaa tctactcctt catgctccaa
    15301 gagccaagct ttcttttcca ctcctgcagc ataacctgtc agacgcttgc ctgctcccaa
    15361 cacacgatga caaggtacta ggatagacca aggattgcgt cccactgctc caccaattgc
    15421 ttgagcagaa gccacttgca ggtcttgagc aatttgtcca taggttactg tctgaccata
    15481 aggaatgccc tgtaaatagt cccaaactct cttttcaaaa ttcgttccga ttggcgccaa
    15541 gagcaagttg gataaatcct gaggcttgcc tttaaagtaa tcatctaagc aagcaataac
    15601 tgggtctaaa ataggatgac taacaacttc ttctatcgtt tcatctccta gtcccctctc
    15661 aaaatgcttc tgctcctgaa cccaaattcc atacaaataa tggtcatcag ctacaagtga
    15721 tagaatacca attggtgagg agtagagtat ttttacatac ttcttttgca ttatttcttt
    15781 aatttttgat aggccaagcg ttcgccatct actggcacct taccaacttg tttaaaacca
    15841 agtttttcaa aaatatgttg cataaccttg ttttcagcat gcgtatctga gcgaaaatca
    15901 agataatcaa aaccttcaat caagccctct aagaaggttt gagcaactcc ttttccctgc
    15961 acatctgctg ccacagcaat acggtgaaag actagatact ctgactctcc agcttgccag
    16021 tttccctcat aaatagcttc ataggcctcc tctggactct tggtcacagc agcataggct
    16081 agcagttctc cctcttccaa ggctacgtag gcttgccctg agatgatatc atcgataata
    16141 acatctgcat ttggatagcc attttgccac tggtcactac cagcatctgc taaacatttt
    16201 ttggcatcct ccatcacctg catgatggca tctacttcat ttggaaaagc taaacgaatt
    16261 tccatctttt ttcctcattt ctgactagtt tctcccatca tagcataatt taagtatttc
    16321 tacaagcagt taaaacttga ctttgtgttt ttgttatttt ataatctagt tatcaaaact
    16381 atataaaaag gagttgaaaa tgaaaactac cttttcctac ccaaaatggg cagaaattcc
    16441 aaacattgac ctctatctgg accaggtttt gctctatgtc aatcaggtct gcgcccctat
    16501 ctctcctaat aaagacaagg gcctaacagc atctatggtc aacaattatg tgaaaaatgg
    16561 ttacctgaca aagcctgaca aaaaaaaata ccaacgccaa cagattgccc gtttgattgc
    16621 tatcacaacc ctcaagtctg tattttctat tcaagaaata gcccagacac ttaatactct
    16681 acaaactcaa gcaagttcag accaactcta cgatgctttt gtggactaca tgaaccaagg
    16741 aattgaccca gctaacccta ttatccaaac cagctgccaa accattaaac tctatcatca
    16801 aactctagac ttaatcgatc atactcaaga ggaggtaatc caatgaacac tagtcttaaa
    16861 ctcagcaaac aactcagttt tggagaggag attgctaata gcgtgaccca tgctgtgggt
    16921 gcagtcatca tgcttatctt gctgcctatt tcatccatct atagttatga agcacacgga
    16981 tttttatcct ctatcggcgt ttccattttc gtcatcagtc tctttctcat gttcctatca
    17041 tccaccattt atcactctat ggcctatggt tcgacccaca aatatgtttt gcgaatcatt
    17101 gaccattcta tgatttacgt tgccattgcc ggctcataca cgcccgttgt cttgaccttg
    17161 atgaataact ggtttggcta tctgattatt gtcatccaat ggggaacgac catctttggt
    17221 attctctata aaatctttgc taaaaaggtc aatgagaaat ttagccttgc tctttacctg
    17281 attatgggct ggttggttct ggctatcatt cctgccatta tcagtcaaac gacacccgtt
    17341 ttttggagtc tcatggtaac tggcggactc tgttatacag ttggagctgg attttatgcc
    17401 aagaaaaaac cttatttcca catgatttgg catctcttta tcctagctgc gtccgtactc
    17461 caatacatcg ctattgttta ttacatgtaa aaaagttgag aaattcaatc tcaacttttt
    17521 tctttacaca tattgataaa gtactggtgc aagcgcacat catcagtcaa ttctggatga
    17581 aaagaactta ccaacatatt tttttcttgg gctgcaacaa tttgattgtt cactgttgct
    17641 aaaatttcta caccctcacc aacactactg ataatcggac cacggataaa ggtcattgga
    17701 atcttgccaa ctcccttaca ttctgcttcc gtgtagaaac ttcctaattg gcgcccataa
    17761 gcattacgct cgaccaccat atccatagtt cctagatgac tctctttctg agaagtgatt
    17821 tccttagcca gcaaaattaa ccccgcacag gtcccaaaca ctggtaagcc agatagaatg
    17881 gcttctcgga tgggaagtag catgttctgg tcacgtaaga gcttgcccat ggttgtagac
    17941 tcaccaccag gcaaaatcaa acccgacaag tcactctgat cttgctgaaa atcatctaga
    18001 tttctgagtt ctacactctc gacacctaat tgatctagca cttttgcatg ttctgcaaag
    18061 gccccttgca aggccaatat tccgattttc atctattttc ctcgttcagc catgagaatt
    18121 tggatttcat tttcattaat accaaccatg gcttctccta aatcttcaga gatttgagct
    18181 aggatttgag gattacggaa gttagtcaca gccttaacaa tggcactcgc tcgtttaaca
    18241 ggatctcctg acttgaaaat acctgaaccg acaaagaccc cctctgcccc taattgcatc
    18301 attaacgcag catctgctgg cgttgcaaca cctccagcag cgaaatttac aactggcaat
    18361 tttccatgtt catgaacata ttggaccaat tctacaggga cttgcaaatc cttggcagca
    18421 acataaagct cgtcctcacg taagttttga atgcggcgaa tttcctgatt catcatacgc
    18481 atatgacgaa cagcttggac tatatcccct gtccctggtt ctcctttggt acgaatcatg
    18541 gaagcacctt cagcgatacg acgcaaggct tcacccaaat ccttagcacc acagacaaaa
    18601 ggaacttgga attctttctt gtccacatgg aaacggtcat cagctggaga tagaacttca
    18661 ctctcgtcga tataatcaat ttcaatagcc tctaaaatct gagcttcaac aaaatgcccg
    18721 attctgacct tagccattac tggaatacta accgcttctt ggatttcctt aatcatcttt
    18781 gggtcgctca tgcgggaaac tcctccagct gcacgaatat cagccggaat tcgttccaag
    18841 gccatcacag ctgccgcacc agcagcttct gcgatacgag cctgttcagg attctgcaca
    18901 tccataataa caccaccctt gagcatctgt gccaaatttt tatttagttc ataacgattt
    18961 tcagtcattt gttttatcct catcatttgt attggtagct accttttcat tttaagtcag
    19021 aacagaatga agcacaagat aaaaaaacta taattgtatg gggacagatt ggctaaaaac
    19081 tatctgacct taacttaagg ccagatagct cattcatttt tatttttcag ccgtaagggc
    19141 agccattgtg atgtagttgt atggtttgtt gaagtgtggc aagaagaaga ggtctgtcaa
    19201 tgccaattta tcaattgtca catgctcttg gatagcaagt gagaacatgt ggattcccat
    19261 gctaattgca atatcatgtg aaaccatttg ggcaccaaga atttcacggc tatctttgtc
    19321 aaagacaatc ttaattgcta cttcatggtt gtcatgtttc atgaattctg gtttttgaag
    19381 atcgttaaag cctgtttcag ttgcgttgta accagcagct ttcgcttttt caagagtcaa
    19441 accagttgaa accatgtgaa gaccgtagat tgagatacca tttgaacctt gaacaccgat
    19501 tccttccaat tcatgtccac aagcattgta ggcaccaacg ataccagtgc gaacagcatt
    19561 tgaagcaaga gcgatatagc ttgtatcttt acgagcattg tcataaacag tcgcacagtc
    19621 accaacagcg taaacgcctg ggatagatgt ttcttgtttc ttgtctacaa ggaaggcacc
    19681 gttgcggaag agttcgatct taccatctgc aagggctgtg tttggacgga aaccaactgc
    19741 aaggataacc atatccacgt caaagctttc tttgtcagta atcaagcgtt caactttacc
    19801 gtcaccttcg attgctttaa cagtttgacc tagagccaag cggatgttgt gatcttccaa
    19861 gttcttcgcc atcatttgtg tgaagtcttt gtcatagtaa ccgttcaaga cagtatcaac
    19921 gatatcaaca aggacaactt cttttccaag acgttcaaag gcttcagcaa gttcaacacc
    19981 gatgtaacca ccaccaacaa cggcgatacg gtcgaggtgt tggctcttgt cagaaagttt
    20041 attgataact tcttcagcat tttggtacaa tttcacgaat tgtacgtttt caagagttgc
    20101 tttaaattcg cggtttcctt taacaatttc aacaccttcg attggtggca agattggtgt
    20161 agaacctgta gcgaaaatca atttttcgta tgattctttg tgctcttttc cttcaacttc
    20221 cgctgtaact actttgttat catagtcgat tgaaagaaca ggtgagttca tgtaaacttt
    20281 agcaccttta gcttccaatt tttctttatc agaatagaac aagccttcag caccgtcaat
    20341 ttgttcacca atccaaagag ccattccaca tcctaggaaa gagatgttag agttttggtc
    20401 aaatacaaca atttcgttct catttccaaa attatccaac atggtattga tacatgctgt
    20461 accagcgtgg ttagcaccga ctacaacgat tttactcata aaaatttcct gccttcattc
    20521 taaatttacc ttactagtat accatttacc gttagcgttt acaagggggg tactattatt
    20581 tcagcatttt ttatcaaaaa taattcccca tttatcctgt tttcaagcct gatgaatttt
    20641 atgagcatat ttcttgactt tttccaaatt ttgtttgtga aaattctaac tttatggtat
    20701 tataataaca tgaaaatgaa atgtaagggc ttcaatttag atgattattt gatattacaa
    20761 cttattttct ataagagaaa ggagttggta gcttgactct tcgttcacat tctgaacggc
    20821 taatggggac tactatcact atttcattag tggatgagca agccgatatc tttctccaaa
    20881 aatcctttga cttgctcaaa gaacttgaat accgcttcaa cgccaatagt caagaatctg
    20941 agttgatgga aatcaattat caagcaggaa tagcccccgt cacggttcat ccagacctgt
    21001 ttgagctgat ttcacttggg ttagagcata gcctagcgct ctctagccac ctcaatatca
    21061 gcattggtcc cttaattcaa acctggcgta tcggtttttc agatgccaag gtcgcccagc
    21121 ctcaagaaat tgaatcggtg ctgcctctaa tcaatcctca tggtatcgag ttagattctt
    21181 ctacttctac tgtgttttta aaacagaaag gaatgaagat cgatctaggt tgtttagcca
    21241 aaggatacag tgcggataag gttgcccaat ttcttaggaa agagggggtg acttctgcct
    21301 tgatcaatct gggagggaat atcctgacca ttggaaaaaa tcaggcaaga ggggataacc
    21361 catggcaaat cgggattcaa gacccagcca atcctagggg aaatcattta atgaccatcc
    21421 ctgttgtcaa taaatctgtc gtgacttcag gcatttatga acgtcacctg accgtcgatg
    21481 gacaagatta ccatcacatt tttgacagtc aaacaggata tcctgttgaa acggaactag
    21541 cgagtctaac aatcatctct gataaatcag tcgatggcga aatctggacg actcgactct
    21601 ttggagaaag acctgcttct atcctctggc aagtcgaaag tttggagggc atcgaagtca
    21661 tcctcatcga taaagaaggc cacctaagct gttcttcagg aattcctact ctatagagac
    21721 aactgtttca atggaatttt aaaattgtat tatgtaaaaa gagaaaggaa atctcatgtt
    21781 aaaacttatt gctattgttg gaacaaattc aaaacgttct acaaaccgtc aattgcttca
    21841 atacatgcaa aaacactttg ctgacaaagc tgaaattgaa cttgttgaaa tcaagaccat
    21901 tcctgtcttc aacaaaccag ctgacaagca agtacctgct gaaatattgg aaattgctgc
    21961 taaaatcgaa gaggcagatg gcgttattat cggtactcct gagtatgatc actctattcc
    22021 agctgttttg atgagcgctc ttgcttggtt gtcttatggt atttacccac ttttgaacaa
    22081 accaatcatg attacaggtg cttcttacgg tacgcttggt tcatctcgtg cccaattgca
    22141 acttcgtcaa atcttgaatg ctcctgaaat caaggcaaat gttcttccag atgaattctt
    22201 gctctcacac tctcttcaag catttaaccc aagtggcgac ttggttgacc ttgatgttat
    22261 caagaaattg gatgccatct ttgatgactt ccgtatcttc gtgaagatta ctgagaaatt
    22321 gcgcaatgcg caagaattgc ttcgcaaaga tgctgaagac tttgactggg aaaatttgta
    22381 agataggaga ccgaaagaat gaaatttgtt ggacttgttg gatcaaacta cgatcaatca
    22441 tataaccgca aactcttgga atttatccgt cgcaatttca aattcaaatt tgaattagaa
    22501 gtacttgaaa tcgacgaagt tccaatgttt aaccaagatg aaaaatggga cgaaagcttc
    22561 caattgcgtt tcttgtataa caagattaca cgtgctgatg gtgtcattat cgccactcct
    22621 gagcacaacc acactatctc agcttcactc aaatctgtac ttgaatggct ttcatacgaa
    22681 gttcatccat ttgaaaacaa gcctgttatg attgtgggtg catcatacta tgaccaagga
    22741 acatcacgtg ctcaagttca ccttcgtaaa atccttgatg ctccaggtgt taatgcctac
    22801 acgcttccag gtaacgaatt ccttcttggt aaagctaagg aagcttttga taacaacgga
    22861 aatatcacca acgaaggcac tgttaaattc cttgaaactt gcttagataa ctttgttaaa
    22921 tacgtaggag tcgtttcgaa attgaaaaaa ccaaaaccaa tcgaatcaga agacttggat
    22981 tgtggaaaac caatcgctac aaccatcaca gaagttgacc ctgacgatcc agaatgggta
    23041 gaaaaagttg cagcaatcac tggtgctgtt tctggtgata cctatgtcaa attggaccac
    23101 ggtatcctaa cagttaacca aattgatatg ttcttgaaag ctatgccatt tgaattgaca
    23161 tacgctgacg acaacaacca attcctctac tacaacaacg ctcaccaaga tccagacact
    23221 atgttcgcta aacgtgtacc acctcaatca ggtagccgta tgtcgactgt tcatggttct
    23281 cttccaccag cacgtatgaa gaacgtagag tgggttatcg gaacacttcg caacggaaac
    23341 caagaatacg tccgtacgat cgttccaggt tctcctgcag gtgttatcaa cactcacaac
    23401 taccaagcaa tgtactatcc tgatggatca tacgctggta tcaatgaaat cgtctttaac
    23461 ttccaaccat ggcttgactg gtacctaaaa gagactggtc aacgtttggt gggtggtagc
    23521 ggaccatttg ctcctgctgc cggagatcat ggagacgccg atgctacttc tggcgcttct
    23581 gattcagggg atgctggagg ccacggtggt gacgcagacg ctacagccgg tgcaagttac
    23641 taatgatagt ttttaggaac cattatggtt ccttttttag cgaaaaaaga ctaacaaaca
    23701 caaactgcta gtctctttgt tatcgtttca tctatccttg ttaaaagaaa gaatacttat
    23761 actcaatgaa aatcaaagag caaactagga agctagccgc aggctgtact taagtacggc
    23821 aaggtgaagc tgacgtggtt tgaatttgat tttcgaagag tattattatg aatttgggtc
    23881 atcaagacta cggccatgta atcctttttc acgttgtact tggcgtagtt tttctggtgt
    23941 aacatcgttt ccttcttcgt ccacaatttt gattccttca atgtggtgac gaacagcgcg
    24001 gcgataacct tcgatgtact cctcacgtag tttggcttgt tccacttttt cttctggtgt
    24061 taagccttct gtttttttct ttttagcaag ctcattgata cgagcaattt ttttcggatc
    24121 catttcttct cctttgtaat aagataaagt ccgtttatca aattttattt agtgttaatt
    24181 tggttaaaac aagcaaactt agctgctttc ttggttagtt gtgacaagat tgccaaacga
    24241 ttttgacgga cagcctgatc ttcagccatt accatagtat tttcaaagaa agcatcaatg
    24301 actgggctaa gcgcaaagag ttgtttcaat tgctgacttg caggtcctga taaaacgagt
    24361 gtttctactg cttctgccaa agctttttct tggtcattct caaatagtgc tgaatcaact
    24421 gtagcaaccc cttctgcctt ctcagccagg ttaaaggcac gagaaagtga ttcaacagat
    24481 ggtttaaaat cttcttcctt gcttacttct acgagagcac ttgctgcttc caacatatct
    24541 gccacaacaa agtttgaacc tgcaagaact gcttccttga tatcttttgg agtagagccc
    24601 atcatcttat caacacgagc cttgataaag tccataacct ctgctttatt ttcataagtc
    24661 aaactgtcaa atttcaatgc ataaaggcta tcaatcagct catccatagc aatgtgccaa
    24721 ccaaaggcat ccaagatacg aaccacacct tgagttgcac gacgaagggc ataagggtca
    24781 ttagaacctg atggaatcaa tcctactgaa aagaaactca aaatcgtatc caatttgtct
    24841 gcaatggcta gaactgcgcc gaccttgctc tctggaagtt ctccttcagc tgatgtaggc
    24901 atgtagtgtt cacgaatagc agctgccacc gctggagttt caccagcaag aagggtgtat
    24961 ttttcaccca taattccttg gagttcgtca aattcaccaa ccatacctgt caacaagtca
    25021 aacttgtaaa tggctgctgc acgagcaagg tcaactgttt catccactga caaaccagct
    25081 ttttctgcca aaagtacagt gatttgaccc gtacgaatca tgtgttcacg aagggaacca
    25141 atcttctcat ggaaggtgac attgtttaat ttttcaacaa gatctgaaat caccaatttt
    25201 tggtcttcac gccagaagaa ttctccgtct tccaagcggg ctaccaagac tttttcattt
    25261 cctttgatga catttttcaa acgctctgcg tttccgttac gaacagaaat gaagtttggc
    25321 aagagttttc catcttgatc acgaacaaca aagtaacgct ggtgttcctt catagaagtc
    25381 accaagactt cttctggaac ttcaaggtat ttagcatcaa aacttcccat gaaggcagtt
    25441 gggtattcaa ccaaattcaa gacttcattc agcaaatccg catcaatttc gatacgtaca
    25501 ccatgttttg cctcaatttc cttgatttgg tcaacaatca tttgctcacg ttcacatgga
    25561 tctgcgatta caaactgctt acgaaggtct tcttcatagc tcaatgctga ctgaattttg
    25621 gtttctttcc ccaagaaacg atggccacgg ctcacacgac ttcccttgat atcaaggaaa
    25681 tccaagtcaa actcttgctc atccaagaga acagttaaag tgtgaacagg gcggatgtat
    25741 tcaaagctat ttccagccca gtgcatgctg acagggaaag tcaatgactt caagacatct
    25801 acaacaccag gaacaatggc ttcaactgct tgaccaactt cttccttagt gacatagaca
    25861 tattcttcac ccttgatttc acggaattcg atatcttcaa cagtcaaacc tttcccacgg
    25921 acaaatcctt gagctgcttt ggtgaagttt ccatcactat ccaaggcaat tttctttgct
    25981 ggtcccttga aatcttctgt caaatcagac tgtttgtctg ataaaccagt cacacgaaca
    26041 gccaaacgac gtggtgttga gaaggtttga atggcttcaa aagacaggcg gttttccttg
    26101 aggaaggctg ccattttttc gcctagttgt ttttcacttg gtgtgacaac ataggctggt
    26161 aattcttcaa gaccgagttc tactaataag ttttttgtca tgttttttcc tttacatttt
    26221 cttcaatctt ttttgatatg caccttaggt actggggacg tcgctaacta actctgtgag
    26281 tctgtatgga aatccaatgc taaatttatc aagatttcca acaatctcat caaagtggat
    26341 ttagctgact gatttttgaa cctaaggttt caaaaatccc cacataacag tacagcgatg
    26401 catatccctc tagcaagtct tcgacttgcc tctaacgatt ttagagtaca gtattactca
    26461 ctattctgca tcttctgcta aaagtttaac tcgtgtttct tcatccaaaa gtgggtaacc
    26521 taggcgtttg cgttctgcaa caaaggtttt ggctacaaca cgggccaagt tacggatacg
    26581 agcgatatag cctgcacgct ctgttacaga tacggcacca cgcgcgtcaa gcagattaaa
    26641 ggtatgtgaa catttgagaa catagtcata ggcagggtgt accaagcctt cttctaatgc
    26701 acgaccagct tctttttcaa acttatcaaa attttcaagc aacatttctt ggtccgaaat
    26761 ttcaaatgaa tattttgagt gctcatactc aggctggata aagatttctc cgtattttac
    26821 accatcagcc cactcgatat catagacaga gtctacttct tgaatgtaag aagccaagcg
    26881 ctccaaacca taggtaactt ccgcagtcac agggctagtt gccaatccac cgacttgttg
    26941 gaaataagtg aactgagtga tttccattcc gtcaagccaa acttcccaac caagaccagc
    27001 tgaaccagtt gatgggtttt cccagttgtc ctcaacaaaa cgaatatcgt gctccaaagg
    27061 attgattccc aatttttcca aagactcaag gtaaagttct tggatatttg atggagaagg
    27121 cttcatgacc acctggaatt ggtggtgttg gtagagacgg ttagggtttt ccccataacg
    27181 accgtcagca ggacgacgtg atggctctac ataagctgca ttccatggct caggtccgat
    27241 agcacgaagg aaagtgtaag gactcattgt tcccgcacct ttttcattat cataagcctg
    27301 cataagcata caaccttggt cattccaaaa ttgttgcaaa gtaaggatga tttcctggaa
    27361 agtcaatttc ttagacattg tttactcctt tagtttttat atttcttttt caattaattt
    27421 ctgctgaaca aaccaatcta acaagggaaa agttttttct gtatttgccc ataaatgata
    27481 agaatctaag accgcttgta cactacctaa attttctacc aacttatcta ctgtcaaaaa
    27541 gctgcgccag tattcataaa aaatacttgc atagttctta tcataagtcg aagaaccaaa
    27601 atcattcaat gaatgccaac catacttctt ctgaaaaagt tctacgagag attgattaca
    27661 aattttttcc gcttgaaatt cctcttctgt caagaaatac ttgcgactaa tatattcaac
    27721 catcccctct tcgaaccaga tataagagtc ataaccatca aaatcatcta aaaaatgctc
    27781 cgaccaatga gctaactcat gtcctacaat ctgtaagagg aaattttcag ataaagaatg
    27841 atagtgactt tctattgctt gagtttgctc agaacactcg tagtccatca attgatacaa
    27901 atacaactct ttccaaacag ctaaatcagg cgccataacc attcgtctat tatttgtata
    27961 ggctggaaca gcgctttccc taataatctg tgtagcagca ttaaaatctg accaaataac
    28021 ggcttgcggt aaatcacaga ctgcaagttc attctttaaa aaagattgat aatctttcaa
    28081 cttttcagta tttcttacta caaaatcacg aaatgtagct agttgactat cgtcttttac
    28141 aagataaagg ttgtccacgg ctctcctttc tttcacacaa tagactgaat aagcaaaaga
    28201 accgcgtccg acaatcctag gttgatttaa cctaggggcg tcagaaacgc ggttccaccc
    28261 taatttatta cttcattgtt tttgaaaata ctacagaaag cgccagctca ttattttgcc
    28321 ctacttggct cccactatcc caagctcgct tgaagaacgc cataagactt tctttcctgc
    28381 tgactattat atcaaaaatt agaataatgt acaattcttt ttatgatttt ctagaaatcc
    28441 acatcatcaa ctcgtggagc acccgattga acagcaatcg tttttaaggt ttctctctcc
    28501 tcatgactca gttcaattcc aaagcaatca agattagctt gaatacgaga ggttgtgaca
    28561 gattttggaa gtggtaaaaa tccttctgcc aagctccagg ccaaggctat ctgagcaatc
    28621 gattttccgt gatttgctgc gatttcttgc acttgcttgc tatcaaatag ttctccctga
    28681 ccaaaaggcc cccaagcttc caataaaatt cccttttcac gacagtaagc tacgacttga
    28741 tcttgataca cacctggcgc caagcgaact tgattgaccg caggaacgat agttgcagtt
    28801 tcaagcaagg catccaaatg atggggaaga aaattgctaa cgccgatagc acggattttc
    28861 ccttcttgat agaggtcttc catcgctctc caaacttccg cattgcgagt tttccatgcg
    28921 tcattttctc tgagcggttt tgggttcggc caatgaatca aatacaaatc caaataatcc
    28981 aagcccagtt tttctataga tttttccaaa gcttgacgag tttgctcata ggtttgctga
    29041 ctattccaaa gcttggtagt tacgaacatt tcttcacgtg gaactccgct atctttgatt
    29101 gcttgaccaa cactttcttc attctgataa atcgccgccg tatcaatatg acgataacca
    29161 gccttcaagg cttctaacac tgcatgatag gcttcttctc catccttagc cttaaaagtt
    29221 ccaaatccca atactggaat ttctactcca ttatttaatt gataggtatt catatgcttc
    29281 tccttctatt ttattcatca attatagcat aagacatttt ttaagtagta ctatcttctg
    29341 taaaaaataa gtctgtcaaa tatctaacag acctattttt tcttgcttat tcatcacgac
    29401 tatagtacag ctcatgagct tttaggcgag tattgagcat ctctggtatg gtcacaaagg
    29461 tataaccttg atttttcaaa tactcaatga cccttggcaa ggcattgact gtcggactgt
    29521 gaatatcatg catcaaaacg atagagccgt tagctacttg atgctgaatt tctgtcaaaa
    29581 tagatgcttc atttttactc ttccagtcca gactatccac atcccacatg ataaagctca
    29641 aatccaagct attgcgaata tcatctgtaa tagcaccata aggtggacgc atgagtttag
    29701 aactagaacc cagcacttta gttagcacat cctcagtatc agtaatctgc tttttagctt
    29761 catcaagaga gagttgcgag agaatcggat ggctccaact atggtttcca acaacatgac
    29821 cttcagattt tatcctcttc accaagtcct cattcccaga aacatttttc ccaagcacaa
    29881 agaaagtcgc tttaatatca tatttagcta gggtctctaa tacctgcggg gtcgttgctg
    29941 gatttggacc atcatcaaag gttagagcga caactttttg atatttctta tcaaagtaag
    30001 attggtacaa ggccgcatct ttttcgagta agtacgaaga ttggataaca tcaaagaaag
    30061 cagatactgg caaggctatc tcttctaaat tttcaagcac aggacttgga taaaggataa
    30121 tctgactatc cttgtaatca aaattccatg cagacaagtc ttggtcagag aagtttttta
    30181 caatctgctc actctggtct tgctctattt ttttatcctc tatgaaggag gtcaactctt
    30241 ttatcagctg ttccttagcc ttactagcat ctgaaaacag ttggtcaagt gtaaaaggtt
    30301 gcccatcttc tgttaagtga acctttccta gactggtctt ttcagtctct tcaactttaa
    30361 aagcaactaa atcatagatt tgtttggtca cattacgatt aacgactccc tttaaacctg
    30421 actcttcttg ctctgtatag tagaaaacaa gattgtcctt actttctagc ttgtccttaa
    30481 catcttgatt tatcaactcc ctaacagagg aaatcacttt ctccccttgg agaggataat
    30541 aggcaatcac ttcggcttgc ccctgacgaa aatgctcctt ctgatttccc tcactcaatt
    30601 gatcatcttt ctcttttttg agcgattcaa tcttttgctc aaaacttttt tgctggtaga
    30661 tcttaaaagc aataaatccg cctaataggc aaatagaaat tgctaaaata ccaatcaaag
    30721 ccaataatac atgtctcgtt ttcccgtgtc tgccacgtcc tagtctactt ttattcatat
    30781 ttatatcata acaaatttga gcaataattt caatgataca atttggcaat ccacaattcc
    30841 tctagcaagc caaagcatct tacatcaact ccaacatccg tatctgtaga gattatgtag
    30901 ttttctatct atggaatttc tagtagattg aagctagaat agtagaccta tacttctaaa
    30961 acattgttag aaatcgattt gattgtcctg atcgatttgt cctgttctca tttcatttta
    31021 ctataaaact atgaaaagct aggtcatctg agaagtaatt actatcgaca attgcgatag
    31081 cgtatactag tgcgatttgt ttgtagctct ggtgggtatc accttcacgt tggcgaattt
    31141 tttctaggtt ttgattaacc tgactgcaca gataaggcca taggcgattg atgaaaaaat
    31201 tctgatgatg atcctgaatt tcgatgataa cttggattcc attatctaac tccgccaaga
    31261 cgtctatact agtatagaaa tcttacgctg agtagggcat ggaaggcaag acgtgaatgt
    31321 tacttccctc caaaatcgtc acattttttg ctggcaagtc cagcatatcg cggataaatt
    31381 gacaaatcat tagttgggct gatacctgga tgtctgagaa tcctcctttt cctccttcta
    31441 ttatagcaca tttttaaatc taggtttgct agattctatg cttctatcta tttattcgga
    31501 aaagaaagct aatagcttat ttgaaatttt ctcctctctg ttggatagtc ccgtctatct
    31561 atgttataat gaaagaagga tttaaaatcg gaaaaggagt atttatgcta aaattaggtg
    31621 tcatcggaac tggcgctatc agccatcatt tcatagaagc agcccatacc agtggagaat
    31681 accaactggt cgcaatctat tctagaaaac tagaaactgc agcaaccttt gcttctcgct
    31741 atcagaatat ccaactattc gatcaattag aagtcttctt caaatcttct tttgatttag
    31801 tctatatcgc cagtccaaac tccttacatt ttgctcaggc aaaagctgcc ttgtctgctg
    31861 gtaaacatgt tattctcgaa aagccagctg tcactcaacc acaagaatgg tttgatttga
    31921 ttcaaacagc tgaaaaaaat aactgtttta tctttgaagc agctcgtaat taccacgaga
    31981 aagcctttac tactatcaaa aactttttag cagataagca agtgttagga gcagatttca
    32041 actatgccaa atactcttcc aagatgcctg acttgttggc tggacaaaca ccaaatgtct
    32101 tttcagaccg ttttgctggt ggagccctca tggatttggg gatttatccc ctctatgctg
    32161 ctgttcgtct ttttgaaaaa gccaatgacg cgacttacca tgctcaacag cttgacaata
    32221 gcattgacct aaatggagat ggtatcctct tctacccaga ctatcaagtt cacatcaagg
    32281 ctggaaaaaa catcacttcc aatcttcctt gcgagattta tacaacagat ggaaccttga
    32341 ctctcaacac gattgagcat attcgctcag ctatttttac cgaccaccaa ggaaatcaag
    32401 tccagattcc tatccaacag gctcctcata cgatgactga ggaagtcgct gcatttgcac
    32461 acatgatcca gcaaccagat ctgaatctct accaaacttg gctgtatgat gcaggctctg
    32521 ttcatgagct actatatacc atgcgccaga ctgctggcat tagatttgag gcagaaaaat
    32581 gaaaaccaaa ctaccgactg aatggcaaga actgagtgac caactcggtt tccaagaatt
    32641 cacccccatt caaactcaac tatttgagcc ccttcttgct ggagaaaacc tcctaggagt
    32701 gagccaaacc ggaactggta agaccctagc gtatctccta ccaagtcttc tcagactaca
    32761 aaagaaaaaa gcccaacaac tcttgattct agcaccaaac acggaacttg ctggacagat
    32821 ttttgatgta tgtaaaacgt gggcagaagc tatcggattg actgctcaac tcttcctttc
    32881 aggttcaagt cagaaacgac aaattgaacg tcttaaaaag gggccagaaa ttctgattgg
    32941 aactcctggc cgtatctttg aactcattaa acttaaaaaa atcaagatga tgaatgtgga
    33001 aaccatcatc ctggatgaat ttgaccaatt actagatgat tctcagattc actttgtaga
    33061 aaaaatcact cactacgcac ctcgtgacca ccaactggtc tacatgagtg ccacgaccaa
    33121 gtttgatcaa gaaaagattg tgccgaatac acgcactatt gatctctctg atcaaaaatt
    33181 ggacaatatc cagcatttct acatgcaggt agaccaacgt catcgagtgg atatactacg
    33241 aaaactggct catgtagagg atttccgtgg tctagtcttc ttcaatagcc tgtcagacct
    33301 tgggaatgcc gaggaaaaac tacagtatcg tgatatattg gctgtttccc tcgctagtga
    33361 tgttaatgtt aaatttagaa aagtcatctt agaaaagttt aaagataacc aactaaccct
    33421 gcttcttgca actgaccttt tggctcgtgg aattgatatc gatagcctag aatgtgtcgt
    33481 aaactttgat attcctagag atagcgaaac ctacacacac cgtgctggcc gtactggccg
    33541 tatgggcaag gaaggatatg ttattactct cgtcactcat ccagaagaaa tcaaaaaact
    33601 taaaaagttt gcaagtatcc gagaaattgt cctaaaaaac caagaactct atatcaaata
    33661 aagccccatt gctctataca catccagtgt atggagcttt tttataagca attcaatttt
    33721 atactcatct gctttcaaaa agcattctag tccatctctg attaacgatg gactttatca
    33781 cctccttctc cagtccttgt atgacatctt gaagttgatt catgacatct tccaaagttc
    33841 gaaaggcttt attcttaaat ccacgtttac gaatctcttt ccacacttgt tcaatggggt
    33901 tcatctctgg tgtgtatgga ggaataaatg caaagccaat attagtcgga atctttaagg
    33961 tacttgattt atgccatata gcattgtcca taacgagtaa aaaataatca tctggataag
    34021 cttgtgaaag ctcttctaaa aagacgttca tccactcagt attacatcca ccagctctta
    34081 agaaaaatga ttcgcctgta tgggcatcaa cagctccata acaatagcga aattctcgta
    34141 tatagtgact atggacatgt ggacctactc ctattggaga ccaacaagat cccagtttac
    34201 tgattctacc gaaaccagca tcatcttggt acatcaagcg aaccttatga aaaggtctac
    34261 tggttttaaa gcgctttctt ttcttcttga attgagattt tatttttaga cgcgacaatg
    34321 gtttgagcat ctgctttcct aggatgttct ggacgtggca taatatttcg ccagccatgg
    34381 cgcttcaaca gttgatagaa ggcatcacgt gtgtaggaac gacctaactc ctttttataa
    34441 gcctgaaata aggcatcaat tgtaacaaat tctcctgcct ctgcagcctt caaatgacgg
    34501 gcaagaaagg ctttctcttc ctcaactgtc atatatgcat ggttacgacc accacgtgtt
    34561 tcttgaagga gagagtcgag tccgaactcc tcatattttt ttacattttg ccaaat
//
LOCUS       DAVLUM010000016        34605 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLUM010000016 DAVLUM010000000
VERSION     DAVLUM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.016"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            1..835
                     /locus_tag="VYN42_000634"
                     /pseudo
     CDS             1..835
                     /locus_tag="VYN42_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(952..1299)
                     /locus_tag="VYN42_000635"
     CDS             complement(952..1299)
                     /locus_tag="VYN42_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1461750.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYANDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1410..3185)
                     /gene="spxB"
                     /locus_tag="VYN42_000636"
     CDS             complement(1410..3185)
                     /gene="spxB"
                     /locus_tag="VYN42_000636"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1461751.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3392..5635)
                     /locus_tag="VYN42_000637"
     CDS             complement(3392..5635)
                     /locus_tag="VYN42_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1461752.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLSLNPELASLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5645..6016)
                     /locus_tag="VYN42_000638"
     CDS             complement(5645..6016)
                     /locus_tag="VYN42_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1461753.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(6027..6422)
                     /locus_tag="VYN42_000639"
     CDS             complement(6027..6422)
                     /locus_tag="VYN42_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1461754.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAEQFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6606..6704
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6788..7579
                     /gene="thiD"
                     /locus_tag="VYN42_000640"
     CDS             6788..7579
                     /gene="thiD"
                     /locus_tag="VYN42_000640"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1461755.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7789..8421)
                     /locus_tag="VYN42_000641"
     CDS             complement(7789..8421)
                     /locus_tag="VYN42_000641"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1461756.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIIQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLSP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8414..9217)
                     /locus_tag="VYN42_000642"
     CDS             complement(8414..9217)
                     /locus_tag="VYN42_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1461757.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLVVSKNQVAVLGNGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9217..9741)
                     /gene="thiW"
                     /locus_tag="VYN42_000643"
     CDS             complement(9217..9741)
                     /gene="thiW"
                     /locus_tag="VYN42_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1461758.1"
                     /translation="MRKRQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9746..10438)
                     /gene="tenA"
                     /locus_tag="VYN42_000644"
     CDS             complement(9746..10438)
                     /gene="tenA"
                     /locus_tag="VYN42_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1461759.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10449..11099)
                     /locus_tag="VYN42_000645"
     CDS             complement(10449..11099)
                     /locus_tag="VYN42_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1461760.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(11101..12486)
                     /locus_tag="VYN42_000646"
     CDS             complement(11101..12486)
                     /locus_tag="VYN42_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461761.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     TSIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLSHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12487..13047)
                     /locus_tag="VYN42_000647"
     CDS             complement(12487..13047)
                     /locus_tag="VYN42_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1461762.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13309..13397)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13606..14235)
                     /locus_tag="VYN42_000648"
     CDS             complement(13606..14235)
                     /locus_tag="VYN42_000648"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1461763.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14237..15019)
                     /gene="thiM"
                     /locus_tag="VYN42_000649"
     CDS             complement(14237..15019)
                     /gene="thiM"
                     /locus_tag="VYN42_000649"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1461764.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            15110..15196
                     /locus_tag="VYN42_000650"
                     /pseudo
     CDS             15110..15196
                     /locus_tag="VYN42_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(15346..16014)
                     /locus_tag="VYN42_000651"
     CDS             complement(15346..16014)
                     /locus_tag="VYN42_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1461765.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(16229..16317)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16571..17707)
                     /gene="lctO"
                     /locus_tag="VYN42_000652"
     CDS             complement(16571..17707)
                     /gene="lctO"
                     /locus_tag="VYN42_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1461766.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18332..19822)
                     /gene="lysS"
                     /locus_tag="VYN42_000653"
     CDS             complement(18332..19822)
                     /gene="lysS"
                     /locus_tag="VYN42_000653"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1461767.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19950..20096)
                     /locus_tag="VYN42_000654"
     CDS             complement(19950..20096)
                     /locus_tag="VYN42_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1461768.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            20322..20990
                     /locus_tag="VYN42_000655"
     CDS             20322..20990
                     /locus_tag="VYN42_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1461769.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20950..21627
                     /locus_tag="VYN42_000656"
     CDS             20950..21627
                     /locus_tag="VYN42_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1461770.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSVIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILILYFAVCYPISKLSTH
                     LEKHWRN"
     gene            21628..22386
                     /locus_tag="VYN42_000657"
                     /pseudo
     CDS             21628..22386
                     /locus_tag="VYN42_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22398..23258
                     /locus_tag="VYN42_000658"
     CDS             22398..23258
                     /locus_tag="VYN42_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1461771.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(23338..23985)
                     /locus_tag="VYN42_000659"
     CDS             complement(23338..23985)
                     /locus_tag="VYN42_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461772.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23982..24680)
                     /locus_tag="VYN42_000660"
     CDS             complement(23982..24680)
                     /locus_tag="VYN42_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461773.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(24690..25442)
                     /locus_tag="VYN42_000661"
     CDS             complement(24690..25442)
                     /locus_tag="VYN42_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461774.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKYFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(25442..26206)
                     /locus_tag="VYN42_000662"
     CDS             complement(25442..26206)
                     /locus_tag="VYN42_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461775.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(26302..26705)
                     /locus_tag="VYN42_000663"
                     /pseudo
     CDS             complement(26302..26705)
                     /locus_tag="VYN42_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26885..27517)
                     /locus_tag="VYN42_000664"
     CDS             complement(26885..27517)
                     /locus_tag="VYN42_000664"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1461776.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSDLIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(27551..28252)
                     /gene="pyrF"
                     /locus_tag="VYN42_000665"
     CDS             complement(27551..28252)
                     /gene="pyrF"
                     /locus_tag="VYN42_000665"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1461777.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIYYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            complement(28485..29663)
                     /gene="divIB"
                     /locus_tag="VYN42_000666"
     CDS             complement(28485..29663)
                     /gene="divIB"
                     /locus_tag="VYN42_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1461778.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEIEESES
                     KEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEESNRNQTTQRSSRR
                     "
     gene            complement(29673..30731)
                     /locus_tag="VYN42_000667"
     CDS             complement(29673..30731)
                     /locus_tag="VYN42_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1461779.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30735..32087)
                     /locus_tag="VYN42_000668"
     CDS             complement(30735..32087)
                     /locus_tag="VYN42_000668"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1461780.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(32191..32832)
                     /locus_tag="VYN42_000669"
     CDS             complement(32191..32832)
                     /locus_tag="VYN42_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461781.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32834..34252)
                     /locus_tag="VYN42_000670"
                     /pseudo
     CDS             complement(32834..34252)
                     /locus_tag="VYN42_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            34419..>34605
                     /locus_tag="VYN42_000671"
     CDS             34419..>34605
                     /locus_tag="VYN42_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEV1461782.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYS"
BASE COUNT        10506 a         7519 c         6268 g        10312 t
ORIGIN      
        1 acacgtggtg gtcgtaacca tgcatatatg acagttgagg aagagaaagc ctttcttgcc
       61 cgccatttga aggctacaga ggcaggagaa tttgttacaa ttgatgcctt atttcaggct
      121 tataaaaagg agttaggtcg ttcctacaca cgtgatgcct tctatcaact gttgaagcgc
      181 catggttggc gaaatattac gccacgtcca gaacatccta agaaagcaga cgctcaaacc
      241 attgttgcgt ctaaaaataa aatctcaatc caagaaggca agaaagcgtt ttaaatatag
      301 tagacgtttt cgtaaggttt gcttgatgta ccaagctgaa gctggtttcg gtagaatcag
      361 taaactggga tcttgttggg ctccaatagg agtaggtcca catatccata gtcactatat
      421 acgagaattt cgctattgtt atggagctgt tgatgcctat acaggcgaat catttttctt
      481 aatagctggt agatgtaata ctgagtggat gaacgccttt ttagaagagc tttcacaagc
      541 ttatccagat gattatcttt tactcgttat ggacaatgct atatggcata aatcaagtac
      601 cttaaagatt ccgactaata ttggttttgc atttattcct ccatacacac cagagatgaa
      661 ccccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata aagcctttcg
      721 aattttggaa gatgtcatga atcaactcca agatgtcata caaggattgg agaaggaggt
      781 gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtatt
      841 atatgcaatt tctttatata aaaagaccgg attgctccga tctttcaata gttcatattc
      901 tcaatttcta ttttaaaaat agctaaggtt aacgtcaaat gactacgcga cctatttcat
      961 acgataaaaa tcaagcacta gaccagcagg tccttgaact aataaggact ctgttcccca
     1021 atcggttaca gttggtccgt gtaaaacctt tataccaagc tcgttcaacc gtttgtagtt
     1081 ctggtctaca tcctcaacct cgatatgaat aatgattcct gactgaaagt tttccaaagg
     1141 aaccaaatga ttttgtgaca acataaggca gtgactacca atcgtaaact gagcaaaacc
     1201 atcattagca taatctgcct ttttatccaa gatatgctcc aagtcagcac agacttgggg
     1261 aacatttgaa acgataatat ctaattgatt taaattcatt tactctcctc cataaaaaga
     1321 ccggattgct ccgatctttt aaagttctgc tctatgaaaa tcaaagaata aagtctacaa
     1381 gtttcatatt tgattttcgg cgagaggaat tatttaattg cgcgtgattg caatccttct
     1441 tcttccaaga agagacggaa tggtacgagt tcttctgctt cgtatttttc cttgaaggct
     1501 ttgatagctt cttctgagtg aagttttgga tccaattcaa gtacttctac tggaagtgga
     1561 cggtgttgag tgatgcgagc atcgatgaca acagttttac cttctttgtt caatttaaca
     1621 gcttctgcaa caactgcatc gatgtcttcg atacggtcaa ctgtgaatcc aacagctcct
     1681 tgagcttccg caattttagc gtagtcagcg tttgtgaagt ctacaccaaa caagtgtttg
     1741 tttgtatctt cgtatttgtt cttgatgaag ccgtactcag catttgagaa gacaaggttg
     1801 ataactggaa ggtcgtattg aacgtttgtg ataacgtctg ggtagcacat gttgaatgct
     1861 ccgtcaccca tgatgttcca tacttggcga tctggattgt ctttcttagc agcgatacca
     1921 ccaggaaggg caatacccat tgtcgcaaag agtggagatg tacgccacat gttcttaggt
     1981 gtcatgtgaa ggtgacgagt agatgtttga gtagtgttac ctacgtcgat tgagtagata
     2041 gcgtcttgat cagcatgttt gttgattgca ttgtaaactt gatacaattg caattcaccc
     2101 tcagttttac cttcgagttt gttcatgtaa tcacgccagt tttggttgtt cttaacgttt
     2161 gcacgccacc atggagttga ttcaactggg tttactttgt caaggatagc tttagctgct
     2221 tgaccagcat caccaaggat tgaagcgtca agggcatgac gtttaccaag tttgtaaggg
     2281 tcgatatcga cttggatgaa tttttcagtg ttcttgaatg cttcgtaaac ttcagcaaat
     2341 gggaagtttg aaccaaggaa aagaactgtg tctgcttcaa agaccacttc gttggctggt
     2401 ttccaaccaa cacggtaagc agaacctgtc aaaccttcat agttccattc gaaagcttca
     2461 aagtttttac cagttgtgat gattggtgct ttgattttac gtgacaattc agtaatcact
     2521 tcaccagctt taacaccacc aaatccagca tagataactg ggcgttcagc attgttcaag
     2581 atttcaacag ctttgtcgat ttcaacttcg ttcaaagcag gagcgatgaa tgagcgttcg
     2641 tatgaacctg aaccgtagta tgagttttca tcgatttctt ggaaaccgaa gtttactgga
     2701 atttcaacaa cagctggacc ttttttagaa actgcagcac ggcaggcttc gtcaattact
     2761 tttggcaatt gctcagcgta agctacacgt ttgttgtaaa cagcgatacc gttgtacatt
     2821 gggttttgat taagctcttg gaaagcatcc atgttcaatt cgttaactgg acgtgatcca
     2881 aggatcgcta ggaatggagt gttatccata gctgcatcgt aaacaccgtt aatcaagtga
     2941 gtcgcacctg gaccacctga accaactgca accccgattg agccgccgaa tttagcttgc
     3001 ataaccgctg caagagcacc tgtctcttcg tggcgaactt gtaagaaacg gatatctttg
     3061 tcttcagcca aagcatccat caatgagctg agtgttcctg atgggatacc gtagattgta
     3121 tctacgcccc atgttttcaa tacgttaagc attgctgcag atgcagtaat tttcccttga
     3181 gtcataatga taactctcct tcaatttttt taaacttgga gaatacgatt acatagaatt
     3241 ggaaacgttc tccaaatttt tactattcca ctgtatcata tttatgctga cttttctaaa
     3301 aatctgctca aaactctcta ttctctattc taatacagtt ttgaaagtgt tgtcatttct
     3361 gttttataac aaagaaatct agtcattact tttagtctat tttactaaaa tttaacagaa
     3421 gggaactggt cagaacagat acagaactaa aggccatggc tagacttgcc aattctgggt
     3481 tgagagacag tccaacacct gaaaagactc ctgctgcaat cggaattccg acaacattgt
     3541 agataaaagc ccagaaaaga ttgagtagaa ttcgatgaaa ggttttctta ctcatatcaa
     3601 aggcacgaac cactcctaaa agattattgg ttgtcaacac caaatctgct gactcgatgg
     3661 cgatatctgt tccagcaccc atagcaattc ccacatctgc tacactaagg gcaggagcgt
     3721 cattgatacc gtccccaaca aaggctactt tgccagccgc ttgcagttta tggatttcat
     3781 gggctttttc ttctggcaag acgcctgcaa tgacctcttc aattccgatt tgatctgcaa
     3841 tagcacgcgc cacaccagca ttgtctcctg tcagcatgac tgttcggaga ccacgttttt
     3901 ttagctgact gatggctagc ttagcatttt ccttaggaat atcttgcaaa gcaagcaagc
     3961 ctttgatttc attgtcaaca gctaagaaca caactgtctt agcttctttt tctagttctt
     4021 ctagtttatc ttgataagta ttagaaatat ccatgccatc cagcatttta gcatttccaa
     4081 gtaaaacttg ttttccattg attcgccctg aaacaccttt cccgtgcaag gcctgaaaat
     4141 tttcaacagt ttgaaactca agtccagctt cactcgctcg cttaacgata gcctcagcca
     4201 gtgggtgttg agaagcatct tccaaggagg ctgccaatcc aaacacttct acttcgtcgc
     4261 cgatgatatc tgttaccaca ggtttccctt ccgtcaaagt cccggtctta tcaaagacaa
     4321 gagtttgaac tttctggatt tcctgtaaga cagttccatt tttgaggaga acccccatct
     4381 tggcactacg tcctgtcccc accataaggg ctgtcggtgt tgcaagtccc aaggcacaag
     4441 gacaggcgat aatcaaaacc gccactccgt agagaagaga ggacacaaag ctagctccaa
     4501 gcacgaccac actatccctg agcaagacga accaaaccca aaaggtcatg attcctaaaa
     4561 tgacaactac tgggacaaaa atccctgaaa tcttatccgt caagtcctga atcggcgcac
     4621 gacttgtctg agctttcttc acaaaatcca caatctgagc caaaacagtc tctgagccaa
     4681 ctttttctgc tctaaagaca agcgttccac tatgattgat ggttgagcca atgacagtat
     4741 ctccaactgt cttgtccaca ggcagactct cacctgtcac catggattcg tcaatactag
     4801 agacaccttc tactacgaca ccatcaacag caatcttttc accgggacgc actcgaatca
     4861 ggtcgcctac cttgacttgt tccaaaggaa cttggacata actatcatca ctcaagactt
     4921 ctgcagtttt agcttgcaag tccagtaatt tctccacagc ttgggacgta ttttttctca
     4981 ttttttcctc aaaaactgct cccaaaagaa cgaaaaagag gataaatcca gcactttcga
     5041 agtaaacagg gagaccagca aagagagcaa ctaggctata gaaataagcc actagagttc
     5101 ccagcgcaac caaggtatcc atgttggcat tgtgcttttt aaaactggcc caagcactct
     5161 ggatatatgg cttacctgca actaacataa taggcgttgt tgctagaaag gttccccaat
     5221 gcatgacttg atgactaatg ctacctgtca acatcccaat catgagaatc acaagaggca
     5281 cagtaaagat actagtaatc caaaaacgtt gcaggagaga tagagatttt cgagtcttct
     5341 caacgactat atagcttccc ttttgcatct tcatgccaca agaaaattca tgtcgcccta
     5401 attcttgagg tgtaaaacga atgactttct cctcatctac gccgattggt tccaagatac
     5461 cttcttcttc aaacagaatt tccttataac agtttgaagg agtagcacga tgaaaggtaa
     5521 tctcagctgg aattcccttt tgaagctgga tatgggctgg atgatagcct ttttcagctc
     5581 ggatacggat tttttgaatg ccattttcta agcttgcttt cacaatttct gtcatagtct
     5641 ccacctactc tacaatcatc ttgccgtgca tcatgttcat accacaagca aagccaaact
     5701 ctccaacctg ctcaggcgtg atttccacta catactcttc ccccattggc aggttcgcat
     5761 gtacaccaaa atctggaaaa acaatttgat ccagacatgg tgaaggatcc ttgcggtcaa
     5821 agacaatgcg tgctggcact gatttcttga ggacaatcaa ctcaggagta tagcctccca
     5881 tgacttccac tcgaatctct tggtatccgt ttttttgctg ggctttttgt ccagattttt
     5941 caggcttttt gaaaaaccaa aacaagataa acgcgataag ggcaatacaa ataatggtta
     6001 caatactatt taacatgacg tctcctttac atacaattac atcttacttc tgttacagca
     6061 cttgatttct tctctgaaat cacagcttcc aagtcttcca agtcagtctg agtaaattca
     6121 cattctacaa tcaagtcagc caacaaattc ctaatcctac gggaacaaac cttgtctttg
     6181 atatcttgga caagtaaatc ccgactttgg tctagagtta aaagggctga ataaacaaag
     6241 aacttgcctt cttttttccg agtcaaacac tctttctcaa ccagacgagc caaaagtgtc
     6301 tgaacagtgg acttggacca atcaaactgc tctgccaaaa ccctaatcaa atctgtactg
     6361 gtctgctccc cctgcatcca aataatcttc atgacctgcc attctgcatc tgaaatctgc
     6421 attaccatac ctccaaaatc tacatttgtc aattacactc atcagtatac tatcaaaatc
     6481 tacatttgtc aattatagaa ataatatttt cttcgaaaaa tagaatttta atcatttgaa
     6541 aaacgatttg cagtcaaata ttactatata aacaataaaa atatgctata ctaaagaaaa
     6601 aagaaaacaa ccactagggg tgcgtaaagc tgagattaac gactgttaga tccctctgac
     6661 tcaatctagg taatgctagc tgatggaagt ggaaatgata atggggacta gcagtcttct
     6721 attgcctttc taaaacagac tagcttgttc ttaagaatac aaacttcagt tggttgggag
     6781 gttttagatg acttatttac ccgttgcttt gaccattgca gggactgacc ctagtggtgg
     6841 tgctggcatt atggcagatt taaagtcatt ccaagcgaga gatgtctatg gaatggctgt
     6901 tgtaaccagt cttgtcgctc aaaataccag aggtgttcag ctaatcgaac acgtttctcc
     6961 tcaaatgttg aaagcccaat tggacagtgt cttttctgat attccacctc aggctgtaaa
     7021 aactggaatg ttggctacta ctgaaatcat ggaaatcatc caaccctatc ttaaaaaact
     7081 ggattgtccc tatgtccttg atcctgttat ggttgctaca agtggagatg ccttgattga
     7141 ctcaaatgct agagactatc tcaaaacaaa cttactacct ctagcaacta ttattacgcc
     7201 aaatcttcct gaagcagaag agattgttgg tttttcaatc catgaccccg aagacatgca
     7261 gcgtgctggt cgcctgattt taaaagaatt tggtcctcag tctgtggtta tcaaaggcgg
     7321 acatctcaaa ggtggtgcta aagatttcct ctttaccaag aatgaacaat ttgtctggga
     7381 aagcccacga attcaaacct gtcacaccca tggtactgga tgtacctttg ctgcagtgat
     7441 tactgctgaa ctagccaagg gcaagagtct ttaccaggca gttgataagg ccaaggcctt
     7501 tatcacaaaa gctattcaag atgcccctca actcggtcat ggttctggtc cagtcaacca
     7561 tacaactttt aaagattaag aaaaaaaact ctctagttcc cactttaagg gaattagaga
     7621 gtttttatac tcttcgaaaa tctcttcaaa ctacgtcagc ttccatctgc aacctcaaaa
     7681 cactgttttg agctgacttc gtcagtctta tctaaaacct caaggcagta ctttgagcaa
     7741 cctgcgacta gctttctagt ttactctttg attttcattg agtattaatt aggaaagaat
     7801 gtcatgcaac tttgttaaaa aggcttgcgt ttttgcctca atatcttctg cttgcatcaa
     7861 atcacgtaca acagctacac cagctatgcc agtgcccata agctgatcaa tattctccga
     7921 agtcaagccg ccaatagcaa ctattggaat ggcaaccgtt tggcaaattg ttttcaaggt
     7981 tgaaatcagg gtgatgggtg cattttcctt ggtggttgtc ggaaaaatgg ctcctgtccc
     8041 caagtaatct gcacctgatt tctccgcttc cagagctctt ttaaccgttt tagcggtgac
     8101 accgaggatt ttttcaggac tcaagacttg tcgggcaacc gaaactggga gttcgtcatc
     8161 tccaatatgc agaccagcag catcaaccgc aagacaaaca tccaaccgat catcgattat
     8221 caagggtacc tgataagcat ctgttatttc cttgacttgt tttgccagtt gataatattg
     8281 attggttgtg agattttttt ctcgcaattg gattatggta acccctgaac ggcaggccgt
     8341 ctcaactttt gcaagaaagc tttccacgga atcttgatag cgattggtta ccagatatag
     8401 tctaagtgct tctctattca taaacctctc ctttgatggt atctagccaa ttttcatctc
     8461 ttcttaggag cgaaagctga ttgagtactt ggtaacgaaa ttcttccaat cccattcctt
     8521 gaacaactat tttctcagca gcgatattga gataagagac tgctaagcaa gaagcttcaa
     8581 aaccagtctt tccttggctg agaaaaacag ctgttaaggc tccaaccaag tctcctgtcc
     8641 ctgttatcca gtctaattca gtacagccat ttcccagtac agcgacctga tttttcgaaa
     8701 cgacgaggtc cttgggacct gtgactaaga aagacatacc aggataggtc tgacaccaat
     8761 ctttcaagac ttgaagcaaa tcctccgttt cttgatcttt agcactcgca tcgaccccaa
     8821 cgccgtggtg ctttaatcca acaagacttc gaatttctga catgtttcct ttaaggaccg
     8881 taggtctata gtctaaaagg tctttaacta agctcttacg aatggatgaa gtcgttacgc
     8941 caaccgcatc tactaccatc gggagagaag attggtttgc atacgaagct gccatgcgga
     9001 ttgctttttc cttctcagct gacaaatgcc ccaaattgat gaagagagcc tgactttgct
     9061 tagtaaaatc aagaacttca cgggaatcat ctgccatgac aggtttgcat cccagagcca
     9121 aaatcccatt tgccagcatc tcacaagaaa tctcattggt catacagtga attagggaac
     9181 tagagcctat aggaaaggga tttgtaaatt cctgcatcag tctatccttt cactaaagaa
     9241 atatccctgc acttttttaa agaattcctg cttgattaaa aatcgaaagg caataaagga
     9301 aatcgctgta ccaatcaagg ttgctccgaa aaatcgaggc gtgtagataa accagctaag
     9361 cttagcagct gatcctgtaa agagtaccat aacaggatag gaaacaatag aaccaataat
     9421 acctgttccc acaatttctc ccaaggcaga aaagtaaaat tttcgaccgt acttataaaa
     9481 gagacctgct agaagggctc caaaagtcgc tcctgtgaga gctaaaggcg gaatcccttg
     9541 agtcgtcata cgtataaagg ctgtcactgt agccatagcc aaggcataaa caggtcccat
     9601 catgattccc gctagaatat tgactacact ggacatcggt gccattccct caatccgaaa
     9661 gataggtgta aggactacat caagggcaat catcatagat aaaatggtca atttgtgaac
     9721 ttgtagttgg cgctttctca tgtttctatt cttctccttt ttctaaagac tgtaaatcgc
     9781 tcttccatgt ctggtgttgg taagccatct cccaaaactt ggcttccata tgaacactga
     9841 tgtggaaggc atctagcatt ttttgcttat ctgtctcatc actttctcga tagagctgat
     9901 tgaccagtgc tccctcctct ctgatctgtt gctctaactc atccgtaata taagtttcaa
     9961 tccattgttg atagagagga tttggtgatg gtttaagatt aagtgatttg cctatatcat
    10021 ggtataacca aggacaagga agcaagcttg caaaagctat ggctaagttc ggttctgcaa
    10081 attgcctata aatatgagaa atgtaatgat aacaggttgg agcgattgga tgttgctcca
    10141 tttcctggtc gttgatttcc aattccttga aaaattgttg gcgaataaat aactcaccct
    10201 ccactaaacc ctgagcattt tgcttcaaga gtcttttcat ctcttggttt gaagtcttat
    10261 cagccaaaag atgatagatt tctgagaaag ccttcagata gtaggcatcc tgaatcaggt
    10321 aatagcggaa aatggcaggt tctaaattcc cctcttgtaa ttgtaaaata aagggatgat
    10381 gaaaggaagc ctgccaagct ttcttggata attccatcgc aatatctgta aattccataa
    10441 taactccttt ataaaaatag actggtttga agcaataaaa agaaaagcag gtagattaat
    10501 tttgtttttt taggaatata aaaagtccga tagctattct tcaactgtgc atgttcgtca
    10561 tatccatgag cagatagagc tctcaggtaa agatggcgcc acctaaagac tgtcatcaga
    10621 accttactgt aaatcaaggg cgaccaaaaa tgcagttctt gaccacgtaa taggcaagct
    10681 tctttgaggg acttgatttc ttgctgaatg agaggaaagg aattgaatac cacaatcaag
    10741 gcataggacc aagagcgtga tagccccttt tgagccaagt acaagagaag ctcttttagt
    10801 gaaatagagg aaacaaagac aaggccgata caaactgtca caaaggccct cgttccaagc
    10861 atgactgcct gtgaagcatc tccgtgtaac tgaactgccc agtagttggc aaaagatggt
    10921 aaaatggcaa gtatgatcat ccaagctaac attttaaatc gacggtaata gagcataaag
    10981 agaatacaaa atgcgactac cgaaagattc agagcaatcg aaggaatgaa agatgtttcc
    11041 aaggataaaa tcagcaagaa gagactgata atcggtgtct gggttgctac tttgaccata
    11101 ctatctcacc tccccttggg tattgctact ctgagatgta agtggtttgg taatggtcac
    11161 ttctttcaca tgactgagcc cctgactagt catctcaatc caataatcaa ccacagaaat
    11221 caaagggtct aaacgatgac taatgagcag aaaacttctt ccttgattcc tctcctccac
    11281 aatccacttg caaaaataat ggcaggctct atcatccaaa cctgcaaaag gttcatctag
    11341 caagatcacg gaagccttac tggtcaagat ggtcaggagc tgaagaattt tttgctgacc
    11401 accacttaat tgatagggac tcttatcgac tgcctgctcc aaatcaaaat atcgtaaagc
    11461 ttgaaaaatc cgctgatttc tttcagaatc aggtccatct aattgaagct cctctcgcag
    11521 actgactcgg ataaactgct tctcagcttc ctgaacaaca cccgtcagat cacggtacaa
    11581 actctttttc tttttcagga ctgtcccctt ccatgcaatg cgccccttat acttttgaaa
    11641 ttgaagaata gagcgaaaga gggttgattt cccgacacca ttgtcaccca ggatacagga
    11701 aatcccttga tagaatgtga aatcagcaat tgaaaagagg gggcgattac caagctcacc
    11761 agtcacacgg ttcatatgga atagttccgg gctagaagca acttcctttg aagcaacctg
    11821 tgtcatctca taggaaggga tttgaaacac ttcccttagt tttccgtctc ttagctcaac
    11881 catatggtcg atataggctt tatagtcaga taaatcatgg tcgcacaaaa taactgtctt
    11941 cccatcaaga gccaactctt ttagaatctc caatatctcg attctgctct tgcggtcaat
    12001 agaagtgaag ggctcatcca agagatagac cctaggattc atggcaaaga ggacagccag
    12061 cgctgctttt tgcttttccc cacctgatag gtgatgaatg ggacggtgta agattgcctc
    12121 gcaacgacat tgctggacaa cctctgctat tttagaatca atttcctgaa ggtgatagcc
    12181 gatattctcc aaggtgaaaa tcagctcctc aaacaagttc tccatggtaa attgatgatt
    12241 gggattttga aagagaatgc caaccttctg gacacgtgcg atgatagaaa gctgactgac
    12301 ctcgctccca tctatcagga cttgaccact atagggaaga gaactgactt gggcaatgac
    12361 ttgaaaaagg ctggattttc ctgaaccact gctcccaact aacaaggtaa aggcttgcgc
    12421 atgaaaagta aaatcaaacg gctcagagaa gattggggac tgaatcgctc gtagttccag
    12481 acccatctat gcttttcctc cagttgcaaa ctgatgatag agtttgacaa tggcacgaac
    12541 caagatggta cagaagaaat aaacagaaat aaaacgtacc acaagtaagg aaaggacaaa
    12601 cggaagggaa aaggcgtagt aacctaactt aatgtattca tagacaaagc taacaagcgt
    12661 aatcccaata ctattagcag ttagagagag ccaactttca tagcgattct tagttacgat
    12721 aaaaccaaat tcacttccca aaccttgaac caagccagac aaaagagctc ctagaccaaa
    12781 ttggctacca taaaggactt cagcaagcgc agctagcact tctccaatcg ttgcacttcc
    12841 gactctcgga acaaagatgg cagcaatggg cgcagccata caccagagac cgaagaggat
    12901 ttcattggca aaggcctgca aaccaagagg tgttaagagt agactgagaa tattatacac
    12961 atatcctgaa ccaacgaaaa ccccaccaaa aaagatagac aagaaagcaa gcaagataac
    13021 atcttttaac tgccattttt tcaacataaa aaactccttt tttaaaagaa aagtggggca
    13081 ctcaagaaga ccgacctaaa tactttgtat agcagattga atttagaaca gtacacagga
    13141 atgctaaaat atttctagaa attaatttga attttctaat tgatttgttc gcatcttatt
    13201 tcaatctact atatcatctt catccagttt cgtaaaagaa aaaactctaa ttacagatac
    13261 gaattagagt tcagcttaca agattagaca gttcttttcg acatacgaaa aaaacatttc
    13321 acatttccct tcgccagtct taactgtatc aggttcaatg ggtatcatct cagcctaaag
    13381 caccccaaat gcctttatta tttaattatg tgattattat aacacacatt ttatactagt
    13441 tcaagaaatt gaactggaaa tacagccttg cactcacaaa gacagcagat ctttcttttg
    13501 caaaaaacaa atgacctgtt tgatgaatta gccattcaag ctgaatctag acatagcttt
    13561 ttaaaaaagg aaaatcctac ttacttagaa tccaaggata gatatctatt gttcactcat
    13621 ttcccgaaca gttttttcta tattttttgc atacgatatt gccgaaatga ttgaaacgcc
    13681 gtcaacattg gtctttataa tgtctttaat atgtttcgtc tgtatcccac caattgcaac
    13741 taaaggcatt tgtggcaata gttttctcat caattcaaga ccttcataac ctatagcacc
    13801 accagcatca tcttttgact gggtatcaaa tacaggccca acacctacat aatctacata
    13861 ttcaactttt gattgttgaa attcttcttc gtttcttata gaaagaccaa ttattttatc
    13921 tggcatcaat tttctaattt catcaacacc aatatcatct tgacctacat gtacgccatc
    13981 ggcgtcaatt tccattgcta aatctatatc gtcattaacg ataaatggaa cattgtattt
    14041 tttacaaagt tctttaattt ggatagctag ctcaagtttt tctaagcctt ctaaagcacc
    14101 ctcacctttt tctcgaaatt gaaataaggt tataccacct tttaaggctt cctcaacgac
    14161 tgtatataga ttttttcctt ggcaagtagt cgttccacaa ataaaatata gttttagtaa
    14221 ttctttatga aacatcttac ttcactcttt tgaattcctt tacatcttca tctgtaatct
    14281 cgtataaggc atttataaat tcagctttaa atgttccagg aagatgtcca ttgggacgtt
    14341 tttctgctat ttctccagcg atattgtaaa ccaacattgc tgtttctaat gatttcaatt
    14401 cttgaccttt ttctagtccg ataaagcttg ctactacagc tcctaataag catcctgtcc
    14461 caatgacttt cggcatcata gcactaccat tatgaatcgt taccacttct ccattaacag
    14521 caatggcatc cacttcacct gttactacta ttggaatatt gaacttctca tttgctgcta
    14581 gagcaatttc gtcaatatta tctacgcccg cactatctac tcctttagat gccacatcta
    14641 ttcctactaa agaggcaatc tcgccagcat ttcctctaat cgctgctagt ttataattgt
    14701 tgattagatc atccgctact ttttttctat attctcctgc tccacaggct acaggatcta
    14761 aaactgctgg gacattatat ttctccgcaa ttttcagagc agcttggtat aatttccaat
    14821 tttcatctgt caatgttcct atgtttatta ataaaccacc agcatacttt aacaaatcct
    14881 ctaaatctgc tggaaactca ctcatggctg gtgaggcgcc cagtgctact aatccatttg
    14941 ctgtgaaatt ttttactaca tcattggtta tacaaatgac caatggtgct ttttctttta
    15001 ataattttaa acttgtcata ttgaaatcct tccttttcac tttatacgat ctactgattt
    15061 cgatttatat ctatctttcg ttaagaaatt tttttcattt acattgaatg atttatactc
    15121 aatgaaaatc aaagagcaaa ctaggaagct aaccgcaggt tgctcaaaac actgctttga
    15181 acctgtagat aagactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac
    15241 tgacgaagtc agtaaccata cctacggcaa ggtgaaactg acgttgtttg aagagatttt
    15301 cgaagagtct tacctcatca aatttgtaaa tatcatgagc cttctctaga cattgtaacc
    15361 aatatcaaaa aaagctaatt ctaaagcgac tgcttgattc cagcgttgct gaagttctgt
    15421 caaatcttct cgatttttac cgacacgatt gagttcgtca accagaaatt gaacccactc
    15481 tgcaaagaaa ggacctctgt ggagattgat ccattccgaa tgaatataga cttcaggtag
    15541 agccaaatct ttagaacccc agtctaaata gagaccttct gcaatgacca gcataaccaa
    15601 aagatgggca tagtctgatg aagccactgc cgaatacatt agatcctgaa aggcttttgt
    15661 tacagggtgc aaagtcactt ctagatagtc attctctgct acttttaact ctttaaaagc
    15721 cttttggaaa taaccatctt catctgcttc aagaaagcct agttgcttgg caaaacgaag
    15781 cttggattca agtttatctg cgtgagctac gcaggcaccc agcatggata agaaggcatc
    15841 aaagaagtga taatcttgaa tcagatagtc ctttaagacc ttattctcaa ttgtccccgc
    15901 aaaaagttcc ttaacaaaac gatgattgat tgcagcctgc caatccttct gactgctttt
    15961 taataattct ccaacagtca aacctggctg aaatgcatag tcttgtgttt ccatatttac
    16021 ttctcctctc tttacttgtt agtaattaat aaaacagcaa gaaatatcaa gcaaaatcgt
    16081 aattccactt gatcctttta aagcacatcg agagcatttg cagagagcta actaaacaag
    16141 cctatccagt ttatataaac aaaaaactcc aattacaatc aagaattaga gttgacttac
    16201 aagattagat cgttcatttc gccatacgaa aaaacgtttc acatttccct tcgccagtct
    16261 taactgtatc aggttcaatg ggtatcatct cagcttaaag caccccaaat gtctctatta
    16321 tttaattact gaaccagtat agcaaaaaat gaaagcccta gcaagatatt tgaccgaaaa
    16381 atatctttat atataataga ttgaaactag aatagtacac atctacttct aaaacattgt
    16441 taaaaatcga tttaactgtc ctgattgatt tgtcctgttt ttattccatt ttactatggt
    16501 tttctatagc gatttattct tccaatacac gaagaaaaac ctccacattc agtggaggca
    16561 atctctttta tcaatacaat tttaagtcac gagggtcaac tgggaaagtt gggttgtatg
    16621 ggttgtgacg gagtttgaag tgtttaacat cttcaatagt ctgagttcca gacaactgca
    16681 taactgtctt caattccgca ttcaagtgtt caaagacttg acgcacacca acactaccgc
    16741 cgagagccaa gccatagata accgggcgac caatagctac caagtctgct cctgaagcca
    16801 aggctttaaa gacatgttga ccacgacgaa caccagagtc aaagacaatt ggcacacgtt
    16861 tatcaactgc ttctgccact tcttgaagcg agtcaaaggc agctggtcca ccgtcgattt
    16921 gacgaccacc gtggttggtt acccagatac cagaagctcc tgcagcaagc gaacgttcaa
    16981 cgtcctcacg gcattgtggt cccttgacat acacaggaag tcctgagtat tcagcgataa
    17041 attctacatc acgtggagac aagcgttgtt tagctgattt gtaaacaaag tccattgatt
    17101 taccagcacc ttctggcagg tattcttcaa caatcggcat gccaactggg aagacaaaac
    17161 cattacgctt atccacttca cgattccccc ctacagtagc atctgccgtc aagacaatcg
    17221 ctttataacc ttcagccttc acacgatcca tgatgtggcg gttgataccg tcatccttac
    17281 taaagtaaaa ttggaaccaa tggggtgtcc cttgaagggc ttcagaaatc tctggaaggt
    17341 caacagtaga gtaagaactg gttgtataaa gagaaccaaa ctcatgcaca ccacgcgcag
    17401 tcgccacttc cccctgttca ttcgctaatt tatgggccgc aacaggcgcc ataatgattg
    17461 gtgaagatag tttttcacct gcaaattcaa tctctgtact tggattttca acatcgcaaa
    17521 gtgtatgagg aacgatgagt ttgtggttaa aggcgcggat attctctctt aaagtgaaag
    17581 tatcttccgc cccactagcg atatagccaa atgctgcttt aggaataact tgttgcgcca
    17641 ttggctccaa atcataggta ttgatgaagt ctacatgacc ttctgcattg cttgttttgt
    17701 atgacataaa atgccctcct tgattaagta agcgtttgct ttttactaca caactataat
    17761 aactcttttt tcaatcattt tcaagagttt tgcttaaaaa ccatcttatt ttttcataca
    17821 atatactagc cctactttcc ttaaactcta aactttagtc tatattaagt gaatcgttga
    17881 gattttttgc tgccaggcat ttgaactact tttttatttg cggattctat ctactaatac
    17941 tataaaaaaa caagtgaata agacaccaga acatcctcta ataggaccta tggacttata
    18001 tcagtcccat atatactgtt taagcaagat actatcctag ttgacgctaa cttcctatcc
    18061 cacttattaa ttttttattt atagtgaatc tgaacaaatc aattggggaa tccaagtcaa
    18121 tttctagtac tttttgaaca gtttcagcgt actatcgtaa aatgaaataa aacatgcaca
    18181 aattgcttag ggaatttaaa ccaatttcta acaatgtctt agaaatcaaa gtgtactatt
    18241 tcaacttcaa tatactacac ttcattttct ccttaaattc agtctctttt tgaatcaaaa
    18301 aatcccctgg taagagccag aggataagaa tttatttcat tgttgggaag agcaatacat
    18361 cacggatagt tgttgtatca gtgaggagca tgcagagacg gtcgataccg attcccaaac
    18421 cacctgttgg tggcataccg tattcaagag cttcaatgta gtcatagtcg attcctgtcg
    18481 cttcatcatc accaagttct ttggctttag cttgggcttc aaaacggcta agttggtcga
    18541 ttgggtcgtt caactcagta aaggcattac cgtactcctt agtcatgata aagagctcga
    18601 aacggtcagt aaagcgttgg tcttcaggat ttttcttagc gagtggagat acagctactg
    18661 gatgtccata gacaaaggtt ggttggatta aagtttcttc aacaaactct tcaaagaagg
    18721 cattgatgat gtgaccaacc tcagtgtagt gtttctcaac tggaactttc ttctcagcag
    18781 cgatagcttt agcttcttcc aaagtcatgt cttgccagaa atcgacacca gtaatttctc
    18841 tgatagcatc caccatatga acacgcttaa atggttcgtt aatcttgatt tcagtacctt
    18901 ggtagttgac tgggccatca cctttgactg atttagcagc gtgttggata atgccttcag
    18961 tcaagtccat gatgtcttgg aagtctgcat aagcttggta aacttcgata gaagtgaact
    19021 cagggttatg agtagcgtcc attccttcgt tacggaagat acggccaatt tcatagacac
    19081 gttccatacc acccacgata aggcgtttta agtgaagctc agtcgcgata cgaagcacca
    19141 tgtcaatgtt ttgggcattg tggtgggtga taaatggacg ggcagcagca ccaccggctt
    19201 cattatgaag aacaggtgtt tccacttcaa ggaatccttt ttggtcaagg taacgacgga
    19261 tttcagagat gatttttgaa cgagtgacaa agcgttcaaa gctttcacga ttagaaatca
    19321 agtcaaggta acgtttacgg taaattgttt caacgtctgt caaaccatgg aatttctcag
    19381 gaagaggacg aagagcctta gacaagtgtg tgatgtgggt tgccttgata gagagttctc
    19441 ccatatccgt acgcatcact tcaccttcga caccaaggaa gtcaccaagg tctgcttttt
    19501 tgaagatttc gtagttttct tcaccgacag catccttacg aacgtagatc tgaatctggc
    19561 cttcgcggtc ttgaaggtgg gcaaaaccaa cttttccttt accacgtttg gttaccaagc
    19621 gtcctgcgat agtagctgtt tcgtttttat cgtgtaattg ttctttatcg aggttggtat
    19681 atttatcttt taattcttgt gaatttgcag tacgttcaaa acgttttccg aaaggatcga
    19741 ttccttgttc gcggagcgca gccatttttt cacggcgaac gatctgctgg tcatttagtt
    19801 cttccatatg ttctgtagac atgggatcct cctagtttta ctcaaaattg aatacgatga
    19861 gtcatttttt gcgatactcc cattttatca taaataagca agaaattcac ggataatctt
    19921 taaaaactaa aaagaacctg acgctaaaat cactggaaag aagtgaaagt atctcccgcc
    19981 ccactagcga tatagccaaa tgctgcttta ggaataactt gttgcgccat tggctccaaa
    20041 tcataggtat tgatgaaatc tacatgacct tctgcattgc ttgttttgta tgacataaaa
    20101 tgtcctcctt aataagtaag cgtttacttt gtgtattaca aaaatatctt aactcttttt
    20161 caaaactttt aaaatatttt gtttggaaat ttcagaaatt ttatgtctat gataaaaatc
    20221 cttataacgg caataaaaaa tagatattat ccaaagaaga ttttaagtgc tacaataact
    20281 gtattatttc tagatgggag gttctatttt tggattgatc cattgttgaa caatatctac
    20341 cactatatca aaaggcattc tttctgacct tgcatattgc agtttgggga attttgggat
    20401 cctttctgct cggtttaatc gttagtatca tccgacatta tcgaatcctt gttttgtcgc
    20461 aagtagcgac agcctacatt gaattgtcac gtaatacgcc ccttttgatt caactcttct
    20521 ttctctactt cggtcttccc cgaatcggga ttgtcctatc ttcagaagtc tgtgcaacgc
    20581 ttgggcttgt ctttttagga ggctcctata tggcagaatc tttccgaagt gggctggaag
    20641 ccatcagtca aacccagcag gagattggcc tcgctattgg tctgacacct ctacaggtct
    20701 tttactatgt ggttcttccg caagcaacag cggtggcact cccctccttt agtgccaatg
    20761 tcattttcct tatcaaggaa acctctgttt tctcagcagt ggctttggcc gacctcatgt
    20821 acgtcgccaa ggatttgatt ggtctctact atgagacaga cattgcgcta gctatgttgg
    20881 tagttgctta tctgatcatg ctgctaccca tctcactggt ctttagctgg atagaaagga
    20941 ggctccgcca tgcaggattc gggaatccaa gtactctttc aaggaaataa tctcctgaga
    21001 atcttacagg gattgggcgt tacgattggg atatccatcc tgtctgtcct cttatccatg
    21061 atgttcggaa cagtcatggg aatcatcatg acctcccatt ctagaatcat acgattttta
    21121 acacgattgt atctggaatt tatccgtatc atgccccagc tggtgctact cttcatcgtt
    21181 tactttggct tggctcgaaa ctttaatatc aatatctcag gtgagacttc agttattatc
    21241 gtttttaccc tctggggaac agctgaaatg ggagacttgg tacgtggagc tatcacttct
    21301 ctccctaaac atcagtttga aagtggacag gcactcggct tgactaatgt tcaactttac
    21361 taccacatca tcatcccaca agtcttgaga agactgctac cgcaggctat caatcttgtc
    21421 actcggatga ttaaaaccac ttcattagtt gttttgattg gggttgtgga agtgaccaaa
    21481 gttggacaac aaatcatcga tagcaatcgc ctgaccatcc caactgcttc attttggatt
    21541 tatggaacca ttctaatctt atatttcgca gtttgctacc ctatttccaa actatccact
    21601 cacttagaaa aacattggag aaactaaatg tctgaaacta tcttagaaat caaggaacta
    21661 aaaaaatcct tcggagacaa tcccatcctc caaggacttt ctctagaaat caaaaaaggg
    21721 gaagttgttg tcatcctagg gccatctggt tgtgggaaaa gtaccctcct tcgttgcctc
    21781 aacggcttag aaagtattca aggtggagat attcttctgg atggtcagtc tatcgttgaa
    21841 aataaaaaag attttcacct agttcgccaa aagattggca tggtctttta aagttatgaa
    21901 ctctttcccc atctggatgt cttacaaaac ctcatcctag gccctatcaa aactcaagga
    21961 tgggacaaga aagaagtaac ggaagaagct ttgcaattac tagatcgtgt cggtttgctg
    22021 gataaacaac atagctttgc ccgtcaatta tctggtggac agaagcaacg tgttgcaatt
    22081 gtccgtgccc tcctaatgca tccagaaatc atcctttttg acgaggtgac tgcttcgctg
    22141 gatccagaaa tggtgcgtga ggtgctggaa cttatcaatg atttggccca agaaggccgt
    22201 accatgattt tagtaaccca cgaaatgcag tttgcccaag ccattgctga ccggattatc
    22261 ttcctcgacc aagggaaaat cgctgaagaa ggaacagctc aagccttctt tatcaatccg
    22321 caaaccaaac gagcccagga atttttaaac gtctttgact ttagccaatt cggctcatat
    22381 ctataaagga gattcttatg aaactattca aaccactctt aactgtttta gcacttgcct
    22441 ttgcccttat ctttatcact gcttgtagct caggtggaaa cgctggttca tcctctggaa
    22501 aaacaactgc caaagctcgc actatcgatg aaatcaaaaa aagcggtgaa ctgcgaatcg
    22561 ccgtgtttgg agataaaaaa ccgtttggct acgttgacaa tgatggttct taccaaggct
    22621 acgatattga actagggaac caactagctc aagaccttgg tgtcaaggtt aaatacattt
    22681 cagtcgatgc tgccaaccgt gcggaatact tgatttcaaa caaggtagat attactcttg
    22741 ctaactttac agtaactgac gaacgtaaga aacaagttga ttttgccctt ccatatatga
    22801 aagtttctct gggtgtcgta tcacctaaga ctggtctcat tacagacgtc aaacaacttg
    22861 aaggtaaaac cttaattgtc acaaaaggaa cgactgctga gacttatttt gaaaagaatc
    22921 atccagaaat caaactccaa aaatacgacc aatacagtga ctcttaccaa gctcttcttg
    22981 acggacgtgg agatgccttt tcaactgaca atacggaagt tctagcttgg gcgcttgaaa
    23041 ataaaggatt tgaagtagga attacttccc tcggtgatcc cgataccatt gcggcagcag
    23101 ttcaaaaagg caaccaagaa ttgctagact tcatcaataa agatattgaa aaattaggca
    23161 aggaaaactt cttccacaag gcctatgaaa aaacacttca cccaacctac ggtgacgctg
    23221 ctaaagcaga tgacctggtt gttgaaggtg gccattaact cttaaaaggg actggatttt
    23281 aagctccaat ccctttttaa gattttacct ataacatcct gagtctatct aagatgttca
    23341 atctgaacac agtgtacata ctttatcttc tattgcatat actttatcac ataagatacg
    23401 aatatcctct tcactatgac tagcaatcaa aattgttgtc cctttttcac tagagagctt
    23461 tctaaacaat gttctcatat tttctacact tgatttatcc aaggcattca taggttcatc
    23521 tagtaaaaga atagagggat tctccataat tgcttgagca atccctagct ttttcctcat
    23581 acctagcgaa taagttttaa ctttctggtc tttttgctca tatagaccaa ctattttcag
    23641 tgtatcattg atttcctgat taccaactac tcctcgtatg cttgccaaat attgtaaatt
    23701 cttaaagcca ctataataat ttataaaacc aggttcttca atcaaagctc ccaaattagc
    23761 tggaattttt ctctcaggaa caatattttc cccattgatt aacacttctc cataagacgg
    23821 actatataaa ccagctatta atttaaacaa tacacttttc cctgagccat tcgcaccagt
    23881 aattcctata atttccccct gtttacaact aaagttaagg ttttgaaaaa cacatgtctt
    23941 ttttaatttc aactcaatat tttttaatat gattatttca ttcattctat aaacctcctc
    24001 ttttgacgag tgaaatagaa aatgctttga aaaagaaaga ctaaaaatag caactgaaga
    24061 aataaatctc gtcctatatc tccattccct cgattcaaaa tataaaatag ataattagtt
    24121 cgatttccta caaatagacc accaaacaca atcatgagta aaaagaaact aacgcaagca
    24181 aagttcattt gtacattcgc tcctagtgcg tataacataa agcaaaacaa gactaacaca
    24241 caagcattca aagaatcaac tataaacaaa actcctatat cccagtttgg taactgtaac
    24301 ataaattgaa tcactagaac ttttaccatg attaaaatga gtccataaag aaaacaggtc
    24361 caaatctgat acctaatcca gagcttaata gaagaaaatc gaatcacttc cataaagaaa
    24421 tcggatgctc ttctacgata tacaactgct agaaaaaatg tatgaataat aaaccaatga
    24481 agcaaccata tagataagac taaaaaagag ttttgactca gattaggccc ttttaaaatt
    24541 tctataacaa gtctatcatt tccttctaac caataccata atcctaaaca aatcaatatc
    24601 caaaaaagaa cataacccca aaagtacttg gtatagatta tctgattcaa cctccacatg
    24661 tgactactta actttcccat ttccaacttt tacactctcc tccagtttct atgaacagaa
    24721 aatacagtca atggaattat gatagatagt aatgtaagcc aataaatcaa tgcatacgga
    24781 ttggaattta ccatatactg aaaaattggc aataatccaa ttatcccatt gttcaactga
    24841 taaatccaga ataaggattc tacaaataaa aaagtaaaca gaaatactaa gctcatgttt
    24901 gattttttaa accaagaaaa actgctaata gtaagtaagg ataaaaagaa atagtatgct
    24961 atataagaga aaaaaaatcc tataaagaaa ctagcattgt ttgcaatact tataccataa
    25021 aattctctta aaaaatcaac ctcctttatc tccaaagaga agctaaaacc attactaaat
    25081 gcaattagaa aaatcaataa aaataaagtc gccgtccaaa tccccgtact aagagctgct
    25141 aatttgaaac taaaactggt aaagtactta attgatttca gacgaatgcg acactccaac
    25201 ctattaaaat agttattcat caaataaaaa aagaacaata tatatgtgaa cggaaagcag
    25261 tatactccag tcgtcatatc ttgaagtaag actaagatcc attctaatac atttggatgg
    25321 attgaatatt ggcgacagcg caataaatat actgtactag ataaaacaca ggatagcagt
    25381 aatataaaat aaaccaatac tgctaagaaa tcttttttat aaaattgaac aaattgtttc
    25441 attatacata gtcctctgaa tgtagaaaaa atgtaccata aacaaccaaa caactaacaa
    25501 ataaaataaa agcaagatgc ccactaacta aggaaagact gatatctttc tgatatccca
    25561 aagctaatgt tgtcacaggt tctaagtaag atagccctaa aatagcccaa aaaataccac
    25621 caaccatcat ataggcaact gggatgaaaa tagctcctat ttttttcttc actagcaaag
    25681 cactagctag tccaaaaata gagaacacag cgccccaaac tccataccag agagtcgtca
    25741 caagactata gagcaactga ttggaatcaa ataattcttt taaggcacca ctataatctc
    25801 caatataaat ttcctgataa ggagtcacta aaagattaat tcctaataat aataaatagg
    25861 ggagaaaaaa gactagaaaa gaagaaataa ttgcagtact acccacaata gccagatact
    25921 tctttttaga aattcgacac aattgtgctg ttagaaaatg actctcagca tcctctatta
    25981 tctgactaga atagggcagt gtacagataa gtgcagctac taggctaatc ggtgaaaatc
    26041 ctcgaataga agaagcggca aaaaaaatgg ataaaccttc aattttataa ataccattga
    26101 aagcaaggaa atttcctaaa ctcatgcaaa gaagggtcaa aaataaagac atataaaatc
    26161 gaggtgattg aacgactcgt acaagattac aaatgaaaaa ttccatcctt actcctcctt
    26221 ataataaaaa tagggtgtag cattcttttt tcatgctaca cccacaatca accatcttta
    26281 aggcttactc tgacaagtaa gttaataaga atctggactc caagaacctg aagtatgaat
    26341 tcttacatga tttccaaatt gtggcgccat agctaatcta gtaccagaac caatataatt
    26401 gtcaccacct ccattatagt acatgacaat cctagagcca gaccccaatg aatataccgg
    26461 ggtaatatct gacccactat aggcgctacg aatagaggta tttaaccttt taccgccacc
    26521 aatgctgtca ttattattaa ttccagcaga ggcgttttct ttctcaagct cactagttgt
    26581 atccgaaccc caacgcggca acgttaaatc ataatctcca atctgtctag ctaaaactgt
    26641 aaggagaaac aaactagatg caattgtaac tacgcaaaaa aggaatatat ttttcttctt
    26701 ttcatgacat cgtcctccta agaagtgata aacaagatag ttgattgatc aatttgatac
    26761 atattacatt ttcattatat caataaaaga aagcgttgtc aatcatttta tttaaaatat
    26821 tgtcatattt taaataaaat ggtaaaagag gctcggtagc ctcgtctctc tttatcttac
    26881 tgacctaacc ttcttgccaa ttttcttggt cttctttaaa gcgttttaga agatcaaggc
    26941 cctctggcgt gatgtaacct tcttcttggg ctagatggat aagatcgcta tagtttgaaa
    27001 gcgtcacaag tttaacacca gcatctgcaa agttcttatc tgcttttggc aattggtagc
    27061 tgaaaatcgc tacaactcca agcacatctg ctccttctcg cttggctgct gctacagctt
    27121 caagaactga accacccgtt gaaataaggt cttcaaccac taccattttt tgaccttgag
    27181 ctacgcgacc ttcgatttga ttaccagctc cgtggtcttt tggtttgcta cggatgtagg
    27241 caaaaggcaa gtccatctta tcagcaataa tggctccgtg tggaatccct gctgttgcag
    27301 ttcctgcaat cacttctact tcaggaaagg cttctttgat agcatccaca aaaccatttt
    27361 caattagggt acgagtttct ggataggcta gtgtcacacg attatcagtg taaatcggtg
    27421 acttgatacc agatgcccaa gtgaagggtt cctctggttt gaggtaaacg gcttggattt
    27481 tcaagaggtg gctagcgata tctttagcaa gtgtcatggt attctccttt tatttttcta
    27541 atctagttct ttaattccag tcctgtgtcc attcatcctt gatggtatga taagctgcaa
    27601 caggatcctc agcttgggta atgggacgtc ccactacgat atagtcactg ccgatttgat
    27661 aggcatcagc aggtgtcatg actcgttttt gatctccaac tgcagcacca gctggacgaa
    27721 tccctggtgt cagacagata aaatctggat tggtagcctg cttgatgact tgtacttcct
    27781 gagccgagca aacaacacca tccaagccag cttcagctgt cttcttggca tagtaaatca
    27841 cagactcttg cagactggtt tggatatttt gaaactcctg catctgggct tctgacgttg
    27901 atgtgagctg cgttacagcg atcaatttag cttgactccc aagaccttca cgcgccgcct
    27961 tcatcatctc tacaccacca gccgcatgaa cattggtcat atccacacca agctgagata
    28021 ggatcttcat tgctgacttg actgtattag gaatgtcatg aagtttgaga tccaaaaaga
    28081 cactatgacc caaacctttt aagtaggaca caatctcagg ccccgctgcg taataaagct
    28141 ccatccctac cttgagataa aggctttctt ctgctgggaa aagagctaaa aattccttga
    28201 ccgcctcaaa actaggaaaa tcaagagcaa tgattggacg atgttctcgc ataggtttct
    28261 ccttttacct ttactagtga gagagtctgg ccaacagaag ccacgaaaaa aggaacctgc
    28321 caacagcaag gttccacgaa aaatgggtag tctccaccct ttcaccgtct aaccttagct
    28381 gcctctctgg actgctttaa aggtttttta ctattctatt atttctacta gcacttgtca
    28441 agtaaaaact tagtcactaa agaactataa gagaaaaggt aaacctagcg acgcgatgaa
    28501 cgctgggtcg tttggtttcg attgctctct tcctcttgtt ttttctcagc ttccttggcc
    28561 tcttgtttgg ctttttcctc agcttccata attaatttat ccgccacagt gtaactgtaa
    28621 attccagctt ccatgtcaat cacactcggt tctgacaatt gtggcttaat cttactgtaa
    28681 tatggcagtt tcttactcat ttcagataga ggaaccaaga cttcgtccga atcattcatg
    28741 gtcaatcgaa ttaaatcgga tgtcaccttg cttggggcta attccacctt ttggatagcc
    28801 gccttgagtt ctgggctaat ttgagcaagt tctgagacaa aaaccttgat ttgttcacta
    28861 tcattaaaga gaactgataa ataagtttct ggtaaactgt tcagactcac agaactagtc
    28921 tcaagctgac cactggaaag aataggataa tgattttcac cagaaatata gtaggccaca
    28981 atatcatatt ccttgacctt aatagtgaac ttagttggaa attgatagac aagttgagct
    29041 gattcaaccc aatagttaga cttaatctgc ttttcatatt ttgccttgtc tagcagaagg
    29101 ttaatcgtat aatccgaatc ctgaatgcct gaagcctgtc gaatatcatc agctgtagtt
    29161 tgcaccgttc cctcaacacg aatatctttc atggtcgcat aaggactgag caagtaggca
    29221 gagacaatca ataaaagcag acttggaaat aaaatcgtga aggctcgcaa gatatggata
    29281 ccaggaatct ttgctttggc tggtttttcc tttatagcct ttttagcaag ctttttatcc
    29341 tgttcctcct tctctttaga ctctgattct tctatctctt ctttttcttt gtcagcctct
    29401 gaggatgcca ctttttcttc agactcttcc ttagctgatt ctgaatcttc ctggtctgtt
    29461 tcactctcct ggtcctgttt atcctctgac ttctcagatt cttctcccat tcgagcttgt
    29521 ctttcctttt ccttctcctc agctagagcc gcctcttctt cagccttctt ttttagatat
    29581 tcttggtttc gtttctgcca ttctgataac tctttcaatt cttcgagggt ttctttgtcc
    29641 tcatttttct tatcttttga catttacttt ccttatgata aatctttttt caacaattga
    29701 taaaaatctg ctagagattt caattcctta gaagctttca tcttagcttg gtaatcttcc
    29761 ttgtgactta gtaagtgaga aagcttctct tccaaactat ccaaggtcaa atcgctttct
    29821 tgaaggtctt ctgcatagcc tttttttaca aagtaagctg cattttcaat ctggtcacca
    29881 cgactagctt cacgaccaag cggcacaatg acatgcaatt ttgctatcgc caagagctca
    29941 aaaatcgtat tggcaccacc tcgtgtcaca acaatatcag ccaattccat caagggttga
    30001 tagagatcgg tcacatagtc aacacgaaaa agattttgcc tcaactcatt cagactagaa
    30061 tctccagtta gattgataat attgtagcgc tctgttagtt ctttcttatg gtctgtcacc
    30121 aattggttaa agacacgagc gcctgcagaa ccgccgacaa acaatacagt tggcaatttg
    30181 ggattaaagt gggtttgaat atccaccaat tcatctggtt ctggagtgtt tttgtccgaa
    30241 accttggtca ccgctcccac atgctcgacc ttagccaaac tcgaagcttg ttcaaaggtt
    30301 gaatacatct tagtcgcaaa tttataggcg attttattgg ccaagcccat agacaggtca
    30361 gattcgtgaa taaagacagg cactcctgac acacgcgcag cgataacagg cggtactgag
    30421 acaaagcccc cctttgaaaa aagggtctgt ggacgcagtc gcaacatgat aaagagcgat
    30481 tggacgattc cccagccaac tttgaagacg tccagcatat tttgccaaga gaaatagcga
    30541 cgcaatttcc cagtcgcaat agaatggaag gtgacatcca aacctgactt aaggatttct
    30601 tggtgttcga taccacgctt gtccccgata tagtggactt cccaaccatc ttcgatgaac
    30661 ttgggcatta acaaaagatt gagggtaacg tgtccaaccg tccccccacc tgtaaagaca
    30721 atttttttca tattttattc ttttaactcc gctactgtgt cgataaagag gtcgccacgt
    30781 acttcaaagt tagcatacat atcccagctg gcattggcag gactaagaag aaccacatct
    30841 ccttgagtcg caagttcata ggccttacgg gtcgcatctg caatatctgt cgcctccaca
    30901 taagcgacac cagccttgtc tgctgcccgt ttgacacgtt ctgcagattg acccaggatg
    30961 accatcttct tgagtccagt aatgtctggc accaattcgt caaactcatt gccacggtcc
    31021 aaaccacctg caatcaagac gaccttgctg ttgtcaaatc ctgataaggc tttttgagta
    31081 gccaagatat tagttgattt actgtcgtta tagaatttaa cacccttgat gtcatccaca
    31141 aactggagac ggtgtttgac accaccgaag gctgaaagag tttccttgat ggtttgattg
    31201 tccacatcac gaagcttggc tacagcaata gtcgcaaggg cattttccac attgtggcta
    31261 cctggaacac cgatttcatt cgctgccatg actacttcac cacggaagta gagttgacca
    31321 tcttccagat aagctccatc aaccttttca agtgttgaaa atggtacaac agtggcttct
    31381 gtcttggaag tcaagtcttt tgccaagtct tgattaaagt tcaagacaag gaaatcagct
    31441 gctgtcatct tgttctggat attccacttg gctgctacat attccgaaaa tgacccatgg
    31501 tagtcgatat gagttggcat gaggttggta ataaccgcaa tctctggatg gaattcttga
    31561 acacccatga gttggaaaga agaaagttcc ataacaagcg tgtccttatc tgatgctatt
    31621 tgagcaacct gactagctgg atagccgata ttccctgata aaagaccatg ttgcccagca
    31681 gcagtcaaaa cttccccaat catagtcgtt gtggttgtct taccgttcga tcctgtgata
    31741 ccaataatcg gtgcttctga aatcaaataa gccaattcca cctcagtcaa gactggaatt
    31801 cccttggcca aagccttttc aatcatggga ttgttgtagg ggatacctgg atttttcacc
    31861 ataagggcaa actcttcatc caagagttcc aaaggatggc cacctgtaat gaccttgatc
    31921 ccttcttcca gcaaactttg ggcagctgga ttgtcctcga aaggtttccc atcatttact
    31981 gtcacaatgg cacctagctt gtccaacaaa cgagctgcag attcaccaga cttggccaag
    32041 cctaaaacaa ggactttctt atttttaaat tgatctatta ctttcatgtc tcgaactcca
    32101 tttctactcc tactatttta ccatttttat ggaaataaaa aagccacaaa gtgtgtttgt
    32161 gactctttct tctgactgaa tcttaccata tcatctatgt gataaatcgg taactcgaat
    32221 gacctgatcc acttgctccc aaatcagagg attatgggtc gcaataataa tggtccgatt
    32281 cggatttttt aaagattcta ggatggaaag taattcctca gagtttttgg ggtctaagga
    32341 agcggttggt tcatctgcga ggatcaaagg tggatccttt aaaattatct tcgctagtgc
    32401 aacacgttgt gcttctcctc ctgataactc aaatataggt tgcttcaaat ccaaataaga
    32461 gaggtttaca cggtttagag cttgtttcat caaagagatt ttctcttttt ccttcaactt
    32521 tttaccaact aaacccagat tgagattctc tttgacggtt tggctttcaa ttaagccaaa
    32581 atcttgaaat aagtatccta agtaatctct aaagaaaaca gaaggcttaa tgtccttaag
    32641 agaagtgcca tcatatatga tttgcccttt gtcatatggc tctaatcgtc caatcatatt
    32701 caagagtgtt gtcttaccac agccacttgt accgattaag gcataaattt tcccaccttc
    32761 aaaatgaaga ttcgtatctg aaaatagctg acggcttcca aattttttag atatattctt
    32821 tagttcaatc atcctatttt cctttcataa ttgtcataga aacacgagat tctttctgcg
    32881 cttgacggta aagcgtcaaa actgcactaa ctagaaagac caataaagtg agcaagccaa
    32941 tcaccaagtc tcgactgctt aaaataaaga gactagcacc aaatacaaaa ctggcaaatt
    33001 ggctaaccat atactgagca tgtgtttcaa aaaatcgtaa acctgaaatt cgtttaatca
    33061 agatatctcg gcggaattgc tcgaaatata gaagattgac agaataaaag agtaacaagg
    33121 aactggctat tccaacaata gctcctaaga ttaaagttgc tgtttcagtt tgaacttcat
    33181 tataacgagt tagataaaca cttcttcctt ctttaagata ggatacttgc tcataaattc
    33241 cagctttctt caagagttct agcccactct catatccttt gataaagagt tgttttccag
    33301 cattgataga ccaactagat aaggatataa aactatcacc tgtagaagtc ggcgtgaata
    33361 caactaaaat cggatcagtc aaatactgag tagatacggg attctcaccg ttattataaa
    33421 caaaccgctt ttctcccatt gaaagataac taacgtgcgc tttcatctca taatccaaag
    33481 gagcacttgc ctcctcacca gattttccat aataactcaa tctttcttca aaaactttct
    33541 taagttctgc ttctcgagag cgcaaatgtt ctgggagcaa gaggataaac tcaccttttt
    33601 ggagatgggc taacttctgt ttggtctcag catctaccac gaccttttcc ttgtccaaat
    33661 aactgggact aacatagagc gtattagcat ctggactata ggtatccagt gtctctccct
    33721 gttcattttt tccttgtgga ttggcaaaat ggagcagatt atcctttaca taaagagctt
    33781 gttcttcttc gattgcttcc ttggcaaagg cataccactt gctctgattt tctgtatctt
    33841 ttcctctatc acctaagcca aaggaaatct ggtaatagtc tgctctgtcc tgccatgctt
    33901 gttttgaaat ttcaagttct ttcaatcgtt ggtaagacgt caaacctgtc ttaacagcgt
    33961 agcctactgt aaaaacagct actaactgac acaatagggt taaagccatc aagcgtttaa
    34021 ggggtaatct tcccttaata acgggaacta atgctttgta actcaaactc attaggtaaa
    34081 ggagcattag taaaattgaa atcgccaata aaaacaacag atagaaacta atcccaaaac
    34141 cataggtggc taacaagata ggataaaaca aaccttgact aaaaagaacg actcccccac
    34201 ctaggaagga aaggagggct gatagaagga gccacttgat atcagtagat aaaccccaat
    34261 tattcacccc aaatctaaaa accatccaga atccttgcct tagcttagat cctggatggt
    34321 ttcttttttc acccaatggg tgttttttac tagacaaaaa agagtttccc ctttatggta
    34381 taagtgtaga aaaaaacaca aaaagaaagg aaactcatat gaacagttta ccaaatcatc
    34441 acttccaaaa caagtctttt taccaactat ctttcgatgg aggtcattta acccagtatg
    34501 gtggtcttat cttttttcag gaactttttt cccagttgaa actaaaagag cggatttcta
    34561 agtatttagt aacgaatgac caacgccgct actgtcgtta ttcgg
//
LOCUS       DAVLUM010000017        34023 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLUM010000017 DAVLUM010000000
VERSION     DAVLUM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.017"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(229..591)
                     /locus_tag="VYN42_000672"
     CDS             complement(229..591)
                     /locus_tag="VYN42_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1461783.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            605..679
                     /locus_tag="VYN42_000673"
                     /pseudo
     CDS             605..679
                     /locus_tag="VYN42_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(906..1064)
                     /locus_tag="VYN42_000674"
                     /pseudo
     CDS             complement(906..1064)
                     /locus_tag="VYN42_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1452..2141)
                     /gene="rplA"
                     /locus_tag="VYN42_000675"
     CDS             complement(1452..2141)
                     /gene="rplA"
                     /locus_tag="VYN42_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1461784.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2349..2774)
                     /gene="rplK"
                     /locus_tag="VYN42_000676"
     CDS             complement(2349..2774)
                     /gene="rplK"
                     /locus_tag="VYN42_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1461785.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2906..3043
                     /locus_tag="VYN42_000677"
     CDS             2906..3043
                     /locus_tag="VYN42_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461786.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDVVS
                     R"
     gene            complement(3083..3799)
                     /locus_tag="VYN42_000678"
     CDS             complement(3083..3799)
                     /locus_tag="VYN42_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1461787.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            complement(3802..4272)
                     /locus_tag="VYN42_000679"
     CDS             complement(3802..4272)
                     /locus_tag="VYN42_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1461788.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(4274..5311)
                     /locus_tag="VYN42_000680"
     CDS             complement(4274..5311)
                     /locus_tag="VYN42_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1461789.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNILAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(5515..6840)
                     /gene="brnQ"
                     /locus_tag="VYN42_000681"
     CDS             complement(5515..6840)
                     /gene="brnQ"
                     /locus_tag="VYN42_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1461790.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7011..7103)
                     /locus_tag="VYN42_000682"
     CDS             complement(7011..7103)
                     /locus_tag="VYN42_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1461791.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7146..7298)
                     /locus_tag="VYN42_000683"
     CDS             complement(7146..7298)
                     /locus_tag="VYN42_000683"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1461792.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7458..8036)
                     /locus_tag="VYN42_000684"
     CDS             complement(7458..8036)
                     /locus_tag="VYN42_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1461793.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8090..9490)
                     /gene="pepV"
                     /locus_tag="VYN42_000685"
     CDS             complement(8090..9490)
                     /gene="pepV"
                     /locus_tag="VYN42_000685"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1461794.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9503..10108)
                     /locus_tag="VYN42_000686"
     CDS             complement(9503..10108)
                     /locus_tag="VYN42_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1461795.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10279..11079
                     /locus_tag="VYN42_000687"
     CDS             10279..11079
                     /locus_tag="VYN42_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1461796.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGENIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11261..12094)
                     /locus_tag="VYN42_000688"
     CDS             complement(11261..12094)
                     /locus_tag="VYN42_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1461797.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLAILIEKHGYVEDVKNFFDF
                     L"
     gene            complement(12084..13928)
                     /gene="uvrC"
                     /locus_tag="VYN42_000689"
     CDS             complement(12084..13928)
                     /gene="uvrC"
                     /locus_tag="VYN42_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1461798.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLRDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALPPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13968..14669)
                     /locus_tag="VYN42_000690"
     CDS             complement(13968..14669)
                     /locus_tag="VYN42_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1461799.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14748..15980)
                     /gene="murN"
                     /locus_tag="VYN42_000691"
     CDS             complement(14748..15980)
                     /gene="murN"
                     /locus_tag="VYN42_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1461800.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15985..17205)
                     /gene="murM"
                     /locus_tag="VYN42_000692"
     CDS             complement(15985..17205)
                     /gene="murM"
                     /locus_tag="VYN42_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1461801.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17317..18096)
                     /locus_tag="VYN42_000693"
     CDS             complement(17317..18096)
                     /locus_tag="VYN42_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1461802.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     SPAYWRGVFGEIKDWTISPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18165..19826)
                     /locus_tag="VYN42_000694"
     CDS             complement(18165..19826)
                     /locus_tag="VYN42_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1461803.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(20001..22223)
                     /gene="recJ"
                     /locus_tag="VYN42_000695"
     CDS             complement(20001..22223)
                     /gene="recJ"
                     /locus_tag="VYN42_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1461804.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIIK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSIPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22500..23259
                     /locus_tag="VYN42_000696"
                     /pseudo
     CDS             22500..23259
                     /locus_tag="VYN42_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            23299..24063
                     /locus_tag="VYN42_000697"
     CDS             23299..24063
                     /locus_tag="VYN42_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1461805.1"
                     /translation="MISLFGLVAAKPVQANTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24076..24753
                     /locus_tag="VYN42_000698"
     CDS             24076..24753
                     /locus_tag="VYN42_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1461806.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24763..25422
                     /locus_tag="VYN42_000699"
     CDS             24763..25422
                     /locus_tag="VYN42_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1461807.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVPVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25718..26908
                     /locus_tag="VYN42_000700"
     CDS             25718..26908
                     /locus_tag="VYN42_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1461808.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQVGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCSPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27229..28110)
                     /locus_tag="VYN42_000701"
     CDS             complement(27229..28110)
                     /locus_tag="VYN42_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1461809.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28251..29579)
                     /gene="vncS"
                     /locus_tag="VYN42_000702"
     CDS             complement(28251..29579)
                     /gene="vncS"
                     /locus_tag="VYN42_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1461810.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGDTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29576..30232)
                     /gene="vncR"
                     /locus_tag="VYN42_000703"
     CDS             complement(29576..30232)
                     /gene="vncR"
                     /locus_tag="VYN42_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1461811.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30281..30364)
                     /gene="pep27"
                     /locus_tag="VYN42_000704"
     CDS             complement(30281..30364)
                     /gene="pep27"
                     /locus_tag="VYN42_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1461812.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(30544..31923)
                     /gene="vex3"
                     /locus_tag="VYN42_000705"
     CDS             complement(30544..31923)
                     /gene="vex3"
                     /locus_tag="VYN42_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1461813.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31975..32622)
                     /gene="vex2"
                     /locus_tag="VYN42_000706"
     CDS             complement(31975..32622)
                     /gene="vex2"
                     /locus_tag="VYN42_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1461814.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKAGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32635..33912)
                     /locus_tag="VYN42_000707"
     CDS             complement(32635..33912)
                     /locus_tag="VYN42_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461815.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9688 a         7757 c         6318 g        10260 t
ORIGIN      
        1 tatacataaa ctaacctcct cattattagc aaggattcta ctgattataa cctaattctt
       61 agactacttc aagactaact gtccaataat aatctacaga taaatcatcc actcttaata
      121 aaattttatt caatccatct actcattccc aaaaggttgc tgtataatgc aagacatttt
      181 tcttactgat tttacttttc cttaccctca atttagtgag ctaataaatt attcttcttc
      241 aaaaggttga gatttatcta gtaactctaa aacattaatg gtaggtagca acattgcttc
      301 actgctatca attgccgaaa ctattgaaac aatagaacgt aaataatgat aaagaatagc
      361 agtaccattt acgtatagaa tatcggtgat attttcatct atatttattt caaaatatcc
      421 tattacagtt acagatattt ttttcatggc atctttgtca actaaagaaa cactaagttt
      481 tacggctcca tgactataat catctgtatg accaacctta actatgggat ataatatatc
      541 gaaggtaaat gtgaacaaac tgattaggaa atttaaacca acttctaaca atctgttata
      601 ctcaatgaaa accaaagagc aaactaggaa actagcctca ggttgctcaa aacactgttt
      661 tgaggttgta gatggaactg acgtagtcag ctcaaaacac tgttttgagg ttgtggatag
      721 aactgacgaa gtcagtaacc atacgcacgg caaggcgacg ttgacgtggt ttgaagagat
      781 tttcgaagag tattagaaag ctcgatggac tattccagat tcattccact agatttcgaa
      841 atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgccgt tcggcatacg
      901 gcggttcaac taactgttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt
      961 ccacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt ctgagctact
     1021 aattgatagt ggtcccccca gccagatacc ttatccgcta tataggcctt attatcacgt
     1081 tcctgttcgt agagccacga tttcgctatc tcttcctctg acgattctta tttccagcgt
     1141 cagacttaaa acggtctatc cccagaccgt tttaatccgc tacctcacga tagtcagact
     1201 tgggaatcgc tattgggttc accggtagca ggtgcccacc gaggacttac acctcaaata
     1261 tataataaaa taaaataaaa tgaaataaga acaggacgaa tcgatcagga cagtcaaatc
     1321 aatttctaac aatgttttag aagtagatgt gtactattct agtttcaatc tactatacaa
     1381 catgcccgtc gtacatcaaa aaaagttgag acatagcgtc ttcaactttt ttacattact
     1441 ttaactactg attaaagtga gtttacgtca actttgatac caacaccttg agtagttgtg
     1501 atagtcaagt ttgttacgta agttccttta gctgtagctg gttttgcttt ttggattgtt
     1561 tcgttgaaag ctttaaagtt ttcaaccaat ttttcagctt caaatgatac tttaccgatg
     1621 attgcttgaa cgttacctgc acggtcagca cggtaagtga ttttaccacc tttagactct
     1681 tcaactgctt tagcaacatc cattgttaca gtaccagttt tagggtttgg catcaagtta
     1741 cgtggtccaa ggacacgtcc aagacgtcca acaagagcca tcatatcagg tgtagcgata
     1801 actacgtcga agtccaacca accgtcgttg attttagcaa caaggtcatc ttcaccaaca
     1861 aagtctgcac cagcagcttt tgcttcttca gcttttgcac cacgtgcgaa aacaagaaca
     1921 cgtgaagttt taccagtacc gtttggcaat accattgctc cacggatttg ttggtcagct
     1981 tttttaacgt cgatgttcaa gttgtaagca acttctacag ttgcatcaaa ttttgcaaag
     2041 ttagtttctt ttgcaagtgc tacagcttct tctacactgt atgcttttgt gctgtcgatt
     2101 ttctcaagag cagcacgaag ttgtttgctt tttttagcca ttttctattc tccttgtaag
     2161 tggttcaatc gattttcatc tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt
     2221 tcagtctact atttttctct tcctacggcc ttaagctccc ttgctgtacc caagtacaag
     2281 cctcagtcac ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt
     2341 gttattgatt agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc
     2401 attgcagact ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt
     2461 acttgtgcac gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca
     2521 acacctgcag cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat
     2581 gatttatctt cgtaaactga gataacaact ggaatgatca taccagcttg gtcagctgta
     2641 cgagcgttga actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt
     2701 ccaaccggtg gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg
     2761 acttttttag ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac
     2821 ctcccacaag tatgtttttc acatacccat ccattataca ctatttatct ggaattgcaa
     2881 gagaaaagtt tattttttgt actcaatgaa aatcaaagag caaactagga agctagccgc
     2941 aggctgctca aagtacagct ttgaggttgc agataaaact gacgaagtca gctcaaaaca
     3001 ctgttttgag gttgtgaata gaaccgacgt agtcagtagg taaggcgacg ctgacgtggt
     3061 ttgaagagat tttcgaagag tattaatcga cgtagtctcc gccttcaaag ccatagtatt
     3121 cttccaaact gagaccactc tcagcaattt cttttgcttc ttttccgaca taacgcaggt
     3181 gccattcctc agccatatag cctgtttctt tttccttacc tttgagataa cggacaacaa
     3241 agccataatc agctgcatgg tccaaaagcc attgggctgc tttttcttct gttaccaaat
     3301 caccatcagt cccaatcaca tcaaaggcca agcctgtctg gtgttcgcta taaccaggtc
     3361 gagcagaata acggtcggca gcttctttcc catcttgatt aacataatct tgatagagtt
     3421 tggtctgagt ttcataactt ctaaaaccac tgtaatgatc gctaatgggg aaacctgcct
     3481 cttgcatggc tttgatgagt ttgaccaact ctgccttggc tgttggattt tcccctggat
     3541 tatagtcttt agacaatgga tagtgtttgt tggctacgat gatttcatcg tatttccctt
     3601 gaatgctgta gtaatcacct ttattgacca cttctgcttt cttctgggca gctccttgag
     3661 acttactacc gactgttcca tcagctttgg ctgtctgttc tgtcttagtt tctccatctt
     3721 cattttttgt tttttcttgt gaacaagctg ctagactcaa ggctagcaaa gctgtcaaga
     3781 ctaggtatct tttcttcatt tctactcctt tatttctaat agtttatcta cttctgacga
     3841 taaacgtttg actaatcttt taatctcatc cggttttgct tggcaggttt ctgctgtcat
     3901 ttcttcaaag ggaacccacc agactggtcc acgacccttg agaccatgac cattcatatc
     3961 acctgtccgt cgtggaaaca gatgccaatg aagatgagca tcgccatttc ctagcagttc
     4021 gatattcatt ttctcagcag caaaggcctt ggcaactgcc tcttggacta aactcatttc
     4081 ttctagaaaa cggagtcttg tctccttttt caaatggtgc aattcgctga catgctcctt
     4141 ggctagaaag agactatagc cttcaaaata ctggtggtct ccaaccacaa gatagcctgt
     4201 ttccaactct ttgacaaagt aaggattttc ttccttcttg atgaggtcaa ttctctgaca
     4261 aataaggcac atattagtcc accaacgtgc tcttaagata agcatcgacc attcgttctg
     4321 ttgcgatcac cgagtcaata tgggtacgct cataggaatg gctagactct ataccagcac
     4381 cgagaagggc gtgtttgact tctgcccctg cagacatagc cgctgaagcg tccgaaccat
     4441 aaaatggata gatatccagc ttaaatggaa tatcttgctc tttcgccaaa gccaccaaat
     4501 gttgacggaa gtcatagtga taaggtccag aagcatcctt gacacagata gacactgtat
     4561 attcgtctgt ttgctggtca tctcccatgg ctcccatatc cacagccaga tattctacta
     4621 cctgagcaag aatgttagag tttgcaccgt gtcccacttc ttcaaagact gaaaaagcaa
     4681 aatgagttgt tacgggcaat tcaatcttct cttccttata aatgcgaagg agattgagca
     4741 aaatcgccgc actgaccttg tcatccaaat ggcgagactt gataaaacct gtctctgtca
     4801 cgacagttcg tgggtcaaaa ctgataaaat caccgacctc aatgccaaga gcacgagttt
     4861 ctttttcact agttactttg gcgtccaaac gcacttccat attgtcttgc gtgcgttctg
     4921 cagttcctgc atccttatag acatggcaag aagtttggtg gatgaggatg gttcctgata
     4981 ctttttcacc tgtgctagcc acatgaatgg tacagttttc tccttcaatc atgttccaag
     5041 gaaagccacc gatacggtcc attttgagac ggccgtctgg tttgacagca cggacaatag
     5101 caccaagcgt atctacatgg gcagtcacat agcgatgttg ctcatcattt tgacctttaa
     5161 tagttacatt gacaccgccc ttggatgtgc gaaccggctg gtaaccaaaa ccttctagag
     5221 tcttgactaa atagtccgca atctcacgag taaagcctgt tggcgacgca atggctgtca
     5281 gttctttgat atattctact gtttgattca tttcttcacc tcttttgcta cctattataa
     5341 cacatttatc atcggataaa aaaagaaaat cactcctgta gacttgacta caaaagtgat
     5401 tttatactca atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt
     5461 acgacaaggc gacgttgacg cggtttgaat ttgattttcg aagagtatta gtgattattc
     5521 catttcaaaa acatcgcttt cttgcttgtt tggtagaacc aatgagagca agattccaac
     5581 aatggctggc accaaccatg ggagagatgc cttggcaaaa ggaagaacgc taacaagatt
     5641 tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt gcaatggcaa taactgtaac
     5701 cacagcaatt gtcaactgca tacctggttt tgaaagggca acaaatttgt tgacaatgac
     5761 aatcataacg atagcaatcg tgattgggta caagataacc agtactggaa ttgagtactt
     5821 gataatcgca tcaagaccca aattggcaat agcaaatcca atcaaggtaa aggctgtcgc
     5881 ataaaccttg tagctgattt gtgggaagcg ctcattaaag aactcagctg ttgacacaat
     5941 caaaccaaca gtcgttgtga agcaggttac ggtaaccata gctgcaagga agagttgagc
     6001 tgttgagcca aagatttctt gagtggcttg tgacaagatg taaacacctg gtgttccacc
     6061 cttcatcgct tcagctggta ctgggaaatg atttccaaga aaacctaaac cgatgtaaag
     6121 agcgctgaag gcaagggcaa caacgatacc aacaacccaa atagttgaaa tgtattcttt
     6181 cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg attacgctaa aggccactga
     6241 ggcaagggcg tccaaggtat tgtaaccttc taggaaacct gtaccaaagg cagaagcttg
     6301 ataagcagct gaagcagctt gaggacttgt tccaccatat ttgatagctc ccagaacgac
     6361 caagataaca atcaaaattg caaagactgg cgttaaaaca cgtccaatgc ggtctaagat
     6421 ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa tacagaaccg taaatacaat
     6481 caagccaagt cctttatttg catccgacaa aagggggcta atccctactt cgtaagctgt
     6541 tgtagcagta cgtggggtag caaagaatgg accgattgac aagtaaagaa ctgagaggta
     6601 aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg tagatatatc ctttaggatt
     6661 tagcgttcca ataataaggg tcaagacggc gataccaacg cctgaaaaga caaaacctgc
     6721 gatggcagga agaaaatgtt ctccagatag agcacctaga gaaggcggaa aaatcaagtt
     6781 ccccgcacca aaaaatattc caaacaggag caaacctgtt agggtacctt ttttagccat
     6841 aaaaatctcc ttcatattta taaaatactg acctagtata ccacgattag gagtctgaaa
     6901 aaagcatcac gaggcaaata ttaaatgttt tcaattttct taaaaataag aattatctaa
     6961 aaataaaact ctcctaccca gtccacacca agtaggagaa atgcaaaatt ttaaagttct
     7021 tcaaaggcta acatgccacc ctggacattg ataacattat aaccttgttc taataggaat
     7081 tggcaagcac gcgccgatct cattccagat ttgcaaataa tataatgcaa gcgatctttg
     7141 tccaattaat cataactatc agccaattga ctaagcggta ggttgtgggc accttctaaa
     7201 tgaagagctg caaactcatc cacttctctc acatccacta aagaaagctg gtcgttttgg
     7261 taaagctggt aaaatgcgtc aaaggctatt tctttcattc tttttcttct aatactcttc
     7321 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtgc gtatgttacc gacttcgtca
     7381 gttttatctg caacttcaaa gctgtacttt gagcagccta cgactagctt cctagtttgc
     7441 tctttgattt tcattgacta taaaatggtt ttaattcttt ttttcaaatc tggcactact
     7501 tctgcctcaa accaaggatt tttggccatc cagatttgat ttcgtggtga tgggtgaact
     7561 agcggaaaat aggctggcag atagtcttta tagtgtttca ccctctccgt taccttccca
     7621 ctgattttct cctgtaaata gtaggcttgg gcatattgcc caatcaagag ggttaactga
     7681 atatcaggca attcctgtaa gagctgcgga tgccattttt ctgcaaaacc tgtacgaggc
     7741 ggaagatcac ccgacttgcc atgtcctgga aagtagaaat ccataggcaa aacagcaaaa
     7801 taacctgaat tgtaaaaggt atcttcatcc acacctagcc agtcccgcaa gcggtcacca
     7861 cttttatctt tccagtaaag gcctgcttct tgagttttaa gtcccggagc ctgaccgatg
     7921 atattgatgc gagcagtttt tggcgctgca aagagaggct caatgccacg ctctgtatag
     7981 ctggcattct gcgaatccgc catgatagcc tgtttgattc tttcgatttg agacatctac
     8041 tttccctcca aaaagaagtc caagcataag atctcagact tctatcgttt tatttgatca
     8101 attcgtaaat agcttcggca taaattgctg ctgctcggaa gagatcgtcc aaggcaataa
     8161 attcattggc ttggtgcatg gtatcaattg agtctgggaa catagcacca taggcaactc
     8221 cgcgctctaa caagcgacca aaggttccac caccgatgac ttgttcatga ccttgtaggc
     8281 ctgtttgttt ttcatagaca ttcaacaagg tttgcacaag tggatcttcc attggcacat
     8341 agtgaggggt atgaccatgt tctgatagac tgacagaagc aactggcaag ttttctagga
     8401 ttgatttgat ttgttctgga cttgttcctt ttggatagcg gatgttaagg gcaatggtat
     8461 tatcagcact tgtttcatcg aagcggaaga ctccggcatt catagaaaga gcacccatct
     8521 tttcatccac atgagcaatc ttgagatttt caccctcatg atcgttcaag agaattttac
     8581 ctgcgatgtc aaggtagtct ttggctggac cagcaaagcc aaactggctg aggaagaggg
     8641 caaggtaagt tgcgccattg acacctgaag caggcatagc accgtgggct gatttaccaa
     8701 tgatcgtcac cttgtatttg ccagcttctt cttggagttc tcctctaagt ttgtgttctg
     8761 caacaaaggc atctagttta gcttgcaagt cagccaaatc acctgaaacg actgctgttg
     8821 ctgattctgg taccatattt tcacgtaaac cacctgtaaa gctgtgaaga cgggcagcac
     8881 ctgtattttc tcctgcaaag tggaggtatt ccgtgatatt tcctttttca ccattgatga
     8941 ttggaaattc agcatctggt gagaaaccga aatctggttt ggcaagtcct acgtgctcaa
     9001 agtagtagtc catgtctgcc cagcctgatt cttcgtctgt tccaacgatg aagcgaactt
     9061 tcttagaagt tggaagaccc aattctttga tgattttcaa accatagtaa caagctgttg
     9121 taggaccctt atcgtccgaa gccccgcgcg cataaaggcg accatctttg atagttggtg
     9181 tgtaaggatc tgtatcccaa ccgctaccag ctggaaccac gtccatatgg gcaaagattc
     9241 cgagaacttc ttctccatca ccaaactcaa aatgtcctgc gtagttatcg acattcttag
     9301 ttggataacc atcacggtct gcgatttcaa ggaatttttc caaggctttt actggaccag
     9361 gtccaaatgg atgttgggca tcagccttgc tatcatcacg ttctgagttg atttccaaaa
     9421 ggctaaacaa gtcagccaag aggtcttctt tgcgtttttc tacttctgct gtaaaatcaa
     9481 ttgctatcat tttttcttct tcctatcttt tttcgatgat ttcatctact ggcaagcggt
     9541 agcttggttc caatttgtcg tctgtgtaac ccactgtgat caagagttct gggcggaaac
     9601 ggtcttcaat ttccaaaacc tcattgactt ttgatttgtc aaaaccaagg ataatattgg
     9661 aaccaattcc ttggtctgta agagcgagaa ccaagttcat agcaaccaaa cctgcattga
     9721 gtgctaggta gtcgctgact tgttgttcat tgtagcgtgc aaattcagct ggcaaatttt
     9781 tcatgaagta ttgaagttgt tcttctgaga aattgttagc accaccaact cgggcaatct
     9841 tacgagcgcg tttggcaagg tctgtatctg taaatagggc aatggttaca ggtgctgatg
     9901 atacctgctc aaagtttgaa ccataagcca actttgccag ttcagcattt ttctcacgaa
     9961 caactacaaa tttccaaggc tggctgttgt gggcgcttgg cgccaaggtt gcaatttcga
    10021 tagccgtacg cacatctttt ggatcaacag gcttatcagt gaaatgcttg gtcgcatgac
    10081 gttttttatt taattcaaga aatttcataa tcgatttcct tttctaattc tactgcttcc
    10141 attctaccat aatttgaaag agcttgcagg gatttttcat gattaagttt ttctatcaca
    10201 gacataaaag atatatattg gtttatcagg aaagtttctg ataaactagc aagtacttta
    10261 catttgaatg gagacagtat gaaaaaattt agcctattac tagctatcct accatttttg
    10321 gttgcctgtg ggaatcaagc tacacccaaa gagactagcg ctcaaaagac aatcgtcctt
    10381 gctacagctg gcgacgtgcc accatttgac tacgaagata aaggcaatct gacaggcttc
    10441 gatatcgaag ttctaaaggc agtagatgaa aaactcagcg actacgagat tcaatttcaa
    10501 agaaccgcct gggaaagtat cttcccagga cttgattctg gtcactatca ggctgcggcc
    10561 aataatttga gttacacaaa agagcgtgct gaaaaatacc tttactcgct tccgatttcc
    10621 aacaatcccc tcgtccttgt cagcaacaag aaaaatcctt tgacttctct tgaccagatc
    10681 gctggtaaaa caacacaaga ggataccgga acttctaacg ctcaattcat caataactgg
    10741 aatcagaaac acactgataa tcccgctaca attgattttt ctggtgagaa tattggtaaa
    10801 cgaatcctag accttgctaa cggagagttt gatttcctag tttttgacaa ggtatccgtt
    10861 caaaagatta tcaaggaccg tggtttagac ctctcagtcg ttgatttacc ttctgcagat
    10921 agccccagca attatatcat tttctcaagc gaccaaaaag agtttaaaga gaaatttgat
    10981 aaagcgctca aagaactcta tcaagacgga accctcgaaa aactcagcaa tacctatcta
    11041 ggtggttctt acctcccaga tcaatctcag ttacaataat actcttcgaa aatctcttca
    11101 aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccta cggctagctt
    11161 cctagtttgc tctttgattt tcattgagta taagatatac taaaagcgat tggaccagcc
    11221 aatcgctttt ttagtttgca ttggctattt taggaaactc ttacaaaaaa tcaaaaaaat
    11281 tcttcacatc ctctacatac ccatgctttt ctattaagat ggctaaaagt tccagattgt
    11341 gcccctgata gttatcgtca cgacgcagtt cttcatacat ttcaataaag ggaagcccct
    11401 tggacttggc caattctaac tcagcctcgt aatcataagc aactttacga aattggatat
    11461 tgaccaattc cccatcttca acttctatca cggcatactg ggcacggtga ttttttaacg
    11521 cctcccaatt aaaatagggc atgccaatcg accctggatt gatgatttgt tgcccttgac
    11581 ttccataacg aagcaactgc ttgtgaacat gaccataaac tgccacgtcc gtttccgcat
    11641 ctagcagttg gtcaaatttc tctgtatcat tctcaactag caagtcacca ccatagttct
    11701 tatttggcaa attatgagag atagaaaagc gcaatccgtc aatttctttc ttttccagca
    11761 aaggcaagct tcgtagccag acaatcgttg caggatccat tcgctccatc aaaaactggg
    11821 tcatacgcaa gagctgaact tcctgtgggt cttctaagcc atattgccca tctaaagcct
    11881 caaggacacg atcatcccaa ttgcctcgaa cacttgctgt gataggaagg tcctttagca
    11941 gggcgactaa gtcatttgcg cctggaccag gaagaaaaat atctcccaga agccaatatt
    12001 cactggcccc ttgattttta gcatctgcaa tcactgcttc tagcgccgtc gcattgccat
    12061 gaacatctga taaaattgcg attttatggt tcattgtggt ttccttccgt ttggtaatct
    12121 actctttctt ctgctacttg aggcaaggct tctccctgcg ggttcaactt tctttgcaca
    12181 gcctctgcaa cgactctagg taccccaact tcgacaatct catccacact ggcttccttg
    12241 attttggtca aagacttgaa atgcttcata agattctgct tgcgtttagg tcccagaccg
    12301 tcaatcccat ccaattgaga tgagaaagaa tttttggagc gcagttggcg gtggaaggta
    12361 atggcaaagc ggtgcacctc atcttggatg cgttggagga ggaaaaattc ctgagaattg
    12421 cgagacaagt ccaccacctc aagcggatct ccaaagagca attcatgggt ttggtgctta
    12481 tcattctttt gcagcccagc aattggaata tccaagccca gttcctcttg gataacctgc
    12541 ttagcgatat tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg aggaggcaaa
    12601 gcctcacgct gtactcgacc atagcgtctg cgaatgacct ctctcatgct ggcatagtcg
    12661 tctggtccaa caaccgtttt tatcttgtac ttacggtaat ccttcttact cggtttaccg
    12721 ttgacaaaga ccaccatagc cgaaacaggg ctagttccca tgatattaga gttatcgaag
    12781 gactcgatac gtactggggt cgggatttgg agcaaacgtc ctagattttc aatagctcct
    12841 tgggtcttct cgacagattt ctctagcagg ttaaatttct gctccagact aacacgtgca
    12901 ttttttatgg ctagattgac cagctgtttt ttctctccac gttggggttt gagaatcttg
    12961 gtatccacca aagccttgac agcctcttcg tcaatatcct gcggaatcag tacctcattg
    13021 ggaactaggt gagatttttc ttgatagaat tgtcctacat aggtcaaaaa atcctcatct
    13081 ggatcattga agtaggggaa gagattgaca tcgcgctcga tgagcttacc ctgacggaca
    13141 aagaaaacct gcacacacat ccagccctta tccacatagt agccaaagac atcgcgattt
    13201 tggagatcct tagccatgac ccgttgcttg gttcgaagcg ttccaatagc ctgaatcagg
    13261 tcacggtatt ccgccgcacg ttcaaactcc atagtctggg ctgccgctgc cattttgccc
    13321 tttagctcat caatgatttt gttatcctgc cctttcagaa aatcagaaac ctcctgggcc
    13381 atagacttga aataagtctc atccttctta cagatggtgt gggccatgca ttgaccgata
    13441 tggtaataaa aacagacctt agagggcggg ttggtacact tacgaaaagg gaatatccga
    13501 tccagcaacc gcttgatttc attggctgcc cccacatcgg gatagggtcc aaaataaaga
    13561 cctccgtcct ttttgacctg acgagtgata atcaagcgtg gatagcgctc attggtgatt
    13621 ttgatgaaag gataggactt gtcatccctg agcatgatat tgtacttggg cttgttttcc
    13681 ttgatcaggt tgatttctag gagaagtgcc tcaatattag actccgtaac aataaattca
    13741 aaatccacaa tttcagacac cagagcctct gtcttggtat catgacttcc acgaaaatag
    13801 gaccgtactc gattacgcag atttttagcc tttcctacat agataatggt gccattttta
    13861 tccttatgaa tgtagcaacc agggctggtc ggcaagagct ctagttttga tttaatcaag
    13921 ttgttcatag ttccattata gcaaaaaaag tagggaaaga tagtacccta ctcactagtc
    13981 tcatatattt ttcggaggtt tgcaacatcc tcttcctgga taccataaaa ggaacctgct
    14041 ggttgcatga cagacttctc atctgtatgg tccaagccaa tcgcatgacc taactcatgt
    14101 tctgccgtat ggacaaggcg ttcataggag tagccatagt atggattgga caaataataa
    14161 tgattcaacc gcaccgttac ggacaagaat tgccctgtta agagattagt ttgactttcc
    14221 gcctctcctg ccacaggagt gcctccgtcg ttcatctccg tagccgtaat atccgcctta
    14281 ctagactcag tcacgagttc aaagttaaaa gcacccgttt gattccagtt ctggattgct
    14341 tctaaataag cctcttgaaa gcgtgaatcc atctgcggat ccaggtaaat acgagcagag
    14401 gcctgtgccc accttccttc agaatgctgg tgactatctg tctggcttaa cttaggcagt
    14461 tgccctgttt tctcccattg gtcaatactt tgttgaccaa tttttactga ccgttctgct
    14521 tgctttagcg ctccttgaaa atccccgttc agataccaga gaagtccgaa agcaagcaca
    14581 cataagagca caactatcca aaccagacgc caaaacaaac gccacacaaa agaaaagaaa
    14641 gcccctatca aacgaaaaag ccagcgcatg tctctccacc tttctagcaa ataagaatta
    14701 ttttactaaa agaagctaaa agaaatctaa atactgactt tttcatctta acgtcctact
    14761 atttttttga gtaactggat agctttgtat tttaaaggcg atggatggta acggaaagta
    14821 cccgctttgc gtacaatata gccattaaaa ttctgtttaa aacgcaaaac accatcactt
    14881 ccatcaaaaa tcccttgaat gcctaggaag ttgtatttag gtattccacg ttttatgctt
    14941 tccaacataa catatttttg aagcagtgca ggggcataga acttattaaa ctcagtgtag
    15001 gaaccactaa agagataagt cgtttcctga ggcatataaa caaataaact accagctaaa
    15061 acaatatctt cttctccata tttttcaatc aagtctcgcg cttctgcttt tcgaacttca
    15121 aacgtttcaa attgactaga atattctctc agttgatttt gttttttctc agaatgagga
    15181 tttttactca aatcaagtcg caacttgtcc aatttttctt ctagtttact ttgttcacct
    15241 tgcaatttgc tcatatactc cgaaaaattc aagcttgcta tgagaaactc cgcttgttct
    15301 ccaaaagtat cataaaaatg ctcataatat tctaaacttt tatcactata ttctctacgt
    15361 tcagaggttt cttttgttat attcttaaaa atcgatagtt cttcacgttt taactttttc
    15421 aaccgaatgc caaaggtttc agcctttttc accaagggtt tacccttttt gctaaaactt
    15481 ttaagcaaac tcttttcagt taattcagtt aaatctttat agtataacca atctggttct
    15541 ccacctgggt aacctgttgt taagccatca aattgataac ctaaatcagt caaaccttga
    15601 ataatacttt ttttctcagc atctattgga ttaccttggc tatcaaaagt ttgataagtt
    15661 tcataaggtt ttacaagcaa ctctaataca ccattttgct tggcatattc ttttaactct
    15721 gcataaaaaa ctggaagagc atcttgttgg gtataaatcg gccccgaatt gagttccata
    15781 tgcagaccac ccagcatggg caagctataa accagagctg caacttgaat ttctccttct
    15841 tgtttcaaag caagataaac aattcgagcc cctctttttt ctagcaaatc ccccatctgg
    15901 acagattgca taaaggaacg agaagaaacc tgatcagaat aagtctgaaa ctcttctttc
    15961 gtgagtgttg ttagtgccat atacttactt tctatgtttt tttcttaatg ttttacggaa
    16021 atcaagagca agtcttaaca gaggatagag aggatgagtg ggcattgtaa attcacccaa
    16081 gtattcttca atcgttggat taaatttttc cttaaaatga taaagtccac cattgagaga
    16141 gttttcaaca ccacctaaat tttgccagac catacctcgc tcaaaggcat agcgagccgt
    16201 ttcataccat gttaaaattg gtgcattgta acgtttaaaa tcatcatcca taccagcata
    16261 tatattgaca gaggtagtac caaattccaa actcaaagta gccgctaaag gaactctcgc
    16321 ttgacctaca tctatatatt cctgcaagaa ggtcaattcc tctaacaaac gttctttttc
    16381 cttcttctgc gcttctactt ttgaagttcg agtcgactca gtaaaggtct cttccaaggc
    16441 tctatttttc gctaactgtt cttctaactc ttgcgaacgt ttagaaacat ccaaagtggc
    16501 caaggtgata taggccttgt ccttaaaatt atctaacaat tttttataat aggcttcatt
    16561 cctcaaatga atctcttttc gcttctcagt ttttttcatc aactccgaaa atgaatctaa
    16621 tagttccagt ccaccatatt gaatctcaag ccctttgttt cgtgctgttc gaatagcctg
    16681 ttttgttgac ttggaaagtt tatcttcttc aaaattttcc ttgtatattt tcgcctgaat
    16741 acgaggttga atggtgtctc ccatttcctc cgtttttcct gaccacctta ctcccatttg
    16801 ttgcaaacta tcaataatag ccagattttc aggaaattct gtcttttcct gattgattaa
    16861 actttgagat aggcaaatac ttgggtcaaa agtcacaaaa accgctctct tactgcgagc
    16921 ataggactta atagactgaa tgacaaaatt caagagttct ttatccccat aatccaatat
    16981 aggtcctctt gggatgtaaa acattttata gcctagcgga agagttctaa tcaaaatact
    17041 agctgtcgcc agtaattttt cttccctgta aacaccaaac ttctcatgtt gccaattaga
    17101 cttaacttcc tcccaagcac tactttgtaa tacattggct aattcatgtt ctttgacaaa
    17161 ctgatcatat tctaatgtgg gaatgccaat ttgataacgg tacatttcct actctctttc
    17221 ctccagtatt ttattactat tctactactt tcgtttgaaa agtctagtga aaacatattt
    17281 tattttagtt ctactccccc tatgctgaag ttcaaactaa gtcagtctct cttctaattt
    17341 gaaatcaatt ggtaaggttg ttaaaaaaac ttccaattgt ttttcccagt agtaccactc
    17401 gtgagttcca gcactatggc tataggtcac atcaaaacct agttttttga gatttttcac
    17461 tgcgagatta ttggcttcgt acaagaaatc ctgttcgcca caccacgccc aaagtttggt
    17521 ctttttatcc gattttttag ccagactttc aagagaatag ggactaattg tccagtcttt
    17581 aatctctcca aaaacacctc tccagtaggc tggacttccc agattttgac tctcaggaga
    17641 aaaatcttga aagctcaatg cacctgaaaa gctagctgca tgagaaaaac gatttgtcgc
    17701 aagagccagt ttgaagcagc cgtagcctcc catagaaaga ccagcgataa aggtcttttc
    17761 acgcttgcta gtcatattag ggaagaagcg tttcagaacc tgtggcaatt cctctgctag
    17821 agccgtgtag tagtcaaaac catactgggt atcggtgtac caaccattgc tggtattggg
    17881 cataacaacg atgagattag ttcctcgaag caagcgttct acattggtcc gcttaagcca
    17941 actattatga tttccagaca tcccgtgcaa aaggtacaag acgggaatat cttcacactc
    18001 tggttcttcc actcgattgg catcagggta gaggacattc accccccact ccatatccaa
    18061 tacttgtgag taatactcga ttttcattac tgccatgatt ttctccttct atttttctat
    18121 aagaaaaagc cgaaactcga ctttctctct gtttatttca acgattattt tgcttccatg
    18181 actactggta aaatagctgg acgacgcttg gtttggtcaa agagatactt ggtcaaatta
    18241 tctcgaacct tccctttaag atctgcccag tcaaagtcat ctccttgaag atactcttct
    18301 accgtttggt taatcaattc tgaactttca cggagaatat cgcgactctt cttgagataa
    18361 acaaatccgc gcgtatgaac acgagcccta gccacaattt tcttctcacg acggttgact
    18421 gtaatagcca cgatgaaaat tccatcctct gacaagacct tacggtcacg aagaacaaca
    18481 tttccaacat caccaatggc attcccatca atcaagatat ctcctgctga aaccgatcca
    18541 gctggaacaa agtctccatt ctcgtaagcc atggtcgtcc cctttttagg aatgaagatg
    18601 cgttctggca acatcccaac tgccatggca gccttagcgt gagcatccaa ctcacgatac
    18661 tccccttgga cagggaagag gtacttaggt tgcaaaagat tgatcatcag ctgcaaatca
    18721 cgcacatttc cgtgccctga tacatgtaaa ctttgggtaa tcaatttgac aaccccacct
    18781 gcctgataaa tcatattttc cacacgcgca acaaaggctt ctttagcaat agacggagcc
    18841 gtagcaatat agactaggtc cccatccttg atttctacat aacgatggcg accaatcgac
    18901 atcttacgaa gtccattgat aggctcaccc atacgacctg tctcaagaat aatcaactca
    18961 tggtcttcaa agcgagacat atctttaggc ttaatcaaaa gaatttcgtt ggctaaagac
    19021 aacttcttaa gacgaatcgc tgtgcggacg atattttcaa tatcaaatcc tgtcaagacg
    19081 atacgtcgac ctgttttatc cgcagcgtca aaaatctgct gaatacgaga aagattactg
    19141 gaaacagctg caacgatgat acgaccttcc cagtcagcaa tagtttgggt aatttcatcc
    19201 ctaacttcac tttcactagc cacctgaata ttgctgtctg cattggccga atcactgagg
    19261 agagccagga cgccgtcacg accaatctct gccaaacgag caaaatcagt tgcataagat
    19321 tcactagccg tttggtcaaa tttgaagtca cctgtataaa cgatgcttcc ttccgatgtc
    19381 ttcaagacaa ttcccagact ctctggaacg gagtaagtcg tagggaagaa ggaaaccact
    19441 gtcccaccaa aatcaatctc cgtattctca tcaatgacat ggaaatcatt aaatttctta
    19501 acggcatcat ttcctttgac aaagagcttt gccaactcaa tggtcaactc agacccaaat
    19561 acaggaactt tagcctctgc caagagatac ggtagagcac caatggcatc cgcatgcccg
    19621 tgggtcaaga aaaccccagc aatacggtcg ctattttcaa aaaggtaatc catgtttgga
    19681 atcaccacat cgacccctaa ttgttcattt tcaggatatt ttaaccctac attcaaaaca
    19741 aaaatggact ctccaatttc agcaatgtac atattttttc cattctcacg cacaccacca
    19801 agtgttgtta aactgatatt actcattttt cctccaaaat cttagtttat cttgattata
    19861 gggcaattct accctcttat tctaaaagtt ctgatacttt cagccgaatc ttttcctacc
    19921 attataccat ttttttgatg attttcaaaa tgaaggtctg ttttcaaaaa agagttgatt
    19981 tcccaactct ttcctaactt ctactctttt tccatcaaaa aatcataaat ttcttgcacc
    20041 gtacccagcg ccatcatttc ttggtcttta acggtttgtt tgagattttg gtaaatttga
    20101 ctttctccta tctcccgctt tggcgcctct ttattgactg tcatcacacc atcttttatc
    20161 gtcacaaagc ctagttcttc aaatacttga atcatcttga ccagcaagat ttgttgaata
    20221 ttaagatatg cagccaaatc tttcagcttg tagcgaatat caaactctgg gaactggtaa
    20281 atagtcttgt acaatttggc aaactgatct ctagtcccat aacctgtcag ataataagcc
    20341 ttgtcaatat catttttgaa atagacagca gagaaatgct gttcctgaaa aatggtcttc
    20401 agctgagtaa tatcctctgg aatgtttttt acgacaacag cttcactagc cgcaagattt
    20461 ggcagttctc caggaaaatc caagactgga acaccttctg gcaagactgc attttttcca
    20521 cgaatgttaa aaagttgaac accttccact cgcgcatcca ccatcatcaa ctggagggca
    20581 gtttggccat tccattggtt gacagacaat ttaaccgcta actctagatt cttggtttga
    20641 gaaaactctg tcgcccatct gccttgacca aaggctacca cttcaaaact cgcctcaccc
    20701 ttggaaattt tcagctttag atgggcatta cctgccccca tagtacgagc actttcgacc
    20761 tgaaaattct tgatataaaa aataggtttc tgattatcca ttccaaaagg agctaaacgt
    20821 tcaaaacttt tgaccgtttc caagctaagt gcctccaaat ccaactcttc atctaggttt
    20881 aacttattct tgccaccagc atctgcacct ttttcacgaa cataatcttc caaaacctga
    20941 gataaatctg agagttgctc aacttccagc gtcatacccg ctgcacctgc atgacctcca
    21001 aaggcgatga agaggtctcg atggggatcc agagcttcaa aaatatcgac cgcttccaca
    21061 ctacgagcac tgcccttggc acgaccgtct tctatattaa gaacaatgac tgtctgtccc
    21121 aattcttcca ataaacgacc agccacgatt cctagaaccc caggattcca gccttccttg
    21181 gccaagacct gaaccttctt ctcaggatcc accatggtct tggcttcttc atagatagac
    21241 tgaacgattt ccttgcgctc ttcgtttttc tggtgaatca taagggcaat ctcatgcgct
    21301 tcctcatcat caaatccagt caacaaatca atggcaggat tgggatcatc caagcgaccc
    21361 aaggcattca aacgaggagc aatctggaaa ccaaccgttt cttctgttac ttcgttggca
    21421 gcaatcccag ccatgtccag catttcttgc agaccaatgc gctgggtatg acccaacatt
    21481 tccagaccat attgaactaa gatacgattt tcatccgtca gactcaccat atctgcaata
    21541 gttccaatag cgaccaaatc aagcaattcc acttgcactt cttctaacag ggcacaagcc
    21601 aacttgaaag caactccaca accagccaaa tatttaaaag gataatccgc atctggatgt
    21661 tcaggatgga caatagcata agcatctggc agggtttcag gtatggaatg atggtctgtc
    21721 acaatgacat ctactcccat agactgagcc aatgcaatag cctcatgacc agcaacccca
    21781 ttgtccaccg tcacaatcaa ggaaatccct tcttgctcga taaagtattt ataaacacta
    21841 gcattagggc catagccatc ggtaaaacga tttggcaggt aaactcggca ctcagcacca
    21901 agttgttcca aactttcctt aataatagaa gctgaagtca tgccatccgc atcgtagtct
    21961 ccataaacga gaatattttc cccttcttca atagcctgac gaatccgctc cactgccttg
    22021 tccatatcat ggagcagata agcatcatgt aagtcctcca aggaaggttc taaaaacttc
    22081 ttcagacttt cttggtcctg aatccctctc tcaaacaata accgagctac ctcaggaccc
    22141 agtccagcct tcttggctat ctttgtaaaa tccgcatctt ctacctgcag ggcaaactgc
    22201 cattcataag taggtgttat caaaaagaca tccactcttt ctaagaattc tattgcttca
    22261 ttataacatg atttagacgt tttctctatc cagattgctt ttttataaca ttttatagta
    22321 tattgaaact agaatagtac acctctactt ctaaaatatt gttagaaatc gatttgattg
    22381 tcccgatcga tttttcctgt tcttatatca ctatagtgaa ttttttcaga tatgatttga
    22441 caagaacatt cttttatcgt agaatcatgt tataaaatat aacacaaggg agatctctca
    22501 tggctttagt agaatttaaa aacgtcgaaa aatattacgg agactaccac gcactccgca
    22561 acatcaatct ccgttttgaa aaaaggacaa gttgttgtcc tgcttggacc ttctggctct
    22621 gggaagtcca ctcttatccg tacgatcaat ggtttagagg ctgttgacaa aggaagtctc
    22681 ctagtcaatg ggcaccaagt tgctggtgcc agccagaaag atttggtacc tcttcgcaag
    22741 gaagtcggca tggtttttca acattttaac ctttatccac acaaaacggt gttagaaaac
    22801 gtaacacttg cacccattga agttctagga attgataaaa aagaagctga aaaaaccgcc
    22861 caaaaatatc tggaatttgt aaatatgtgg gacaagaaag attcctatcc cgccatgcta
    22921 tctggtggac aaaaacagcg gatcgccatc gctcgtggtc ttgctatgca tccggaactc
    22981 ctcctctttg atgaaccaac atctgctctt gatcctgaga ctatcggaga tgttctagca
    23041 gttatgcaga aactggcgca tgatgggatg aacatgatca tcgttaccca cgaaatgggc
    23101 tttgctcgag aggttgcgga ccgcattatc tttatggccg acggagaagt tttagtagat
    23161 atgacagatg tcgatagctt ttttgacaat ccaagcgaac ctcgtgccca acaattcctc
    23221 agcaaaatta tcaaccacga aagtgacaaa gtcaaataag gaggcgccta tgaaaaaaaa
    23281 ttctttttat cagcattatt gattagcctt ttcggccttg ttgctgccaa accagtccag
    23341 gctaatacta gtatcgcaga cattcaaaaa agaggcgaac tggttgtcgg cgtcaaacaa
    23401 gacgttccca attttggtta caaagatccc aagaccggta cttattctgg tatcgaaacc
    23461 gacttggcca agatggtagc tgatgaactc aaggtcaaga ttcgctatgt gccggttaca
    23521 gcacaaaccc gcggccccct tctagacaat gaacaggtcg atatggatat cgcgaccttt
    23581 accatcacgg acgaacgcaa aaaactctac aactttacca gtccctacta cacagacgct
    23641 tctggatttt tggtcaataa atctgccaaa atcaaaaaga ttgaggacct aaacggcaaa
    23701 accatcggag tcgcccaagg ctccatcacc caacgcctga ttactgaact gggcaaaaag
    23761 aaaggtctaa cctttaaatt tgtcgaactt ggttcctacc cagaattgat tacttccctt
    23821 cacgctcatc gtattgatgc cttttccgtt gaccgctcta ttctgtctgg ctacactagt
    23881 aaacgcacag aactactaga tgatagtttc aagccatctg actacggtat tgttaccaag
    23941 aaatcaaata cagagctcaa cgactatctt gataacttgg ttactaaatg gagcaaggat
    24001 ggtagtttgc agaaacttta tgaccgttac aagctcaaac catctagcca tactgcagat
    24061 taaggaggac accccatgac agatttatca tcttggacag cctattttca ggattttgga
    24121 caatttttca atggtttcct ctttactctt gccctagcga ttggatcctt tatcctcgcc
    24181 atggtcttag gaatcttctt tggtgccatg tcaaccagta aacgtccaat tttacgcatt
    24241 ttagctcgca tctttgttga attttaccaa aatactcccc tcttggtgca gtttgttatt
    24301 gttttttatg gcctacctct tatcagtgac catatcatca tgattccaat ttattggaca
    24361 gccgttctct gcgtgggact ctatcacggc gcttatatcg ctgaggttat tcgttcaggg
    24421 attcagtcta ttcctagtgg tcagatggag gccgccttgt cgcaaggttt tacctatatc
    24481 agtgccatgc gcttgattac cttgcctcag gccttccgca tcattctacc tccattgacc
    24541 aaccaaattg ttaacctcat caagaacacc tctactgtag ctatcatctc tggagtagac
    24601 ttgatgtttg tgactaagtc ttggtcggct ctcaacggaa actatatccc agccttttta
    24661 ggtgctgctc ttctctactt tgccctatgc ttccctgttg cccagtttgg tcgcaagatg
    24721 gagcaagcca acaaaaaagc ctattcactt taggaggtta ctatggaatc tattttagaa
    24781 gttttaaccc cagataacct agtctttatc tttaaaggat ttggcttgac cctctatatt
    24841 tctctgattg ccatcatcct ctctactatc atcggtacgg tgctagctgt catgagaaat
    24901 ggcaaaaatc ctatcttacg cattatttcc agtatttata tcgagtttgt gcgcaacgtt
    24961 cccaaccttc tctggatttt tactatcttt ttggtgttca aaatgaagtc cacaccagca
    25021 ggtattacag cctttactct ctttacatca gcagccttgg ctgagattat tcgaggcggt
    25081 ctcaatgccg tagacaaggg acaatacgaa gcaggaatgt cacaaggctt cacctcagcc
    25141 caaatcctct actacatcat tctcccacaa gccatccgca aaatgctacc agccatcatt
    25201 tctcagtttg ttcccgtgat taaggatacc agtctcctct actctgttat cgccctacaa
    25261 gaactctttg gagccagcca aattctcatg ggccgttatt tcgaaccaga gcaggtcttc
    25321 agtctttaca tcctgattgc cctcatctac ttcagcttta acctagcaat ttctagcctg
    25381 tctcatatgc tagccaaacg ttggcaacaa gctgcagaat aatactcttc gaaaatctct
    25441 tcaaaccacg tctgcttcac cttgccgtat atatgttact gacttcgtca gttctatcca
    25501 caacctcaaa acggtgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt
    25561 tcattgagta taaacagcca ctctccagtt caattggaga gtttttttga tgagagtaga
    25621 tatttataaa cctcaatttg acaccataca ttttctatga taaaatgtaa caaatttatt
    25681 tacaacaaat cgaaatctaa atgaaatgga attttctatg aaatcaatca aaggactact
    25741 ctttatcata gctagtttta tcttgactct tttgacttgg atgaacactt ctccccaatt
    25801 catgattcca ggactagctt taacaagcct atctctgact tttatcctag ccactcgtct
    25861 cccactacta gaaagctggt ttcacggttt ggagaaggtc tacaccgtcc acaaattcac
    25921 agcctttctc tccatcatcc tactaatctt tcataacttt agtatgggcg gtttgtgggg
    25981 ctctcgctta gctgctcagt ttggcaatct tgccatctat atctttgcca gcatcatcct
    26041 tgtcgcctat ttaggcaaat acatccaata cgaagcttgg cgatggattc accgcctggt
    26101 ttacctagcc tatattttag gactctttca catctacatg ataatgggca atcgtctcct
    26161 tacatttaat cttctaagtt ttcttgttgg tagctatgcc cttttaggct tactagctgg
    26221 tttttatatc atttttctat atcaaaagat ttccttcccc tatctaggga aaattaccca
    26281 tctcaaacgc ttaaatcacg atactagaga aattcaaatc catcttagca gacctttcaa
    26341 ctatcaatca ggacaatttg cctttctaaa gattttccaa gaaggctttg aaagtgctcc
    26401 gcatcccttt tctatctcag gaggtcatgg tcaaactctt tactttactg ttaaaaattc
    26461 aggcgaccat accaagaata tctatgataa tcttcaagtc ggcagcaaag taaccctaga
    26521 cagagcttac ggacacatga tcatagaaga aggacgagaa aatcaggttt ggattgctgg
    26581 aggtattggg atcaccccct tcatctctta catccgtgaa catcctattt tagataaacg
    26641 ggttcacttc tactatagct tccgtggaga agaaaatgca gtctaccttg atttactccg
    26701 tgactatgct cagaaaaatc ctaattttga actccatcta atcgacagta cgaaagacgg
    26761 ctatcttaat tttgaacaaa aagaagtgcc cgaacatgca accgtctata tgtgtagtcc
    26821 tatttctatg atgaaggcac ttgccaaaca gattaagaaa caaaatccaa aaacagagct
    26881 tatttacgaa ggattcaagt tcaaataagt aatcatactc tcctgggaaa tcccaggaga
    26941 gttttttata gccaaatgaa ataagacagg aacgatggaa ttttggcatt caaatcaatt
    27001 gataagaatg ttttatagtg gagtgaaata ggatacgaac aaattgatta ggaaaatcaa
    27061 atgaatttat agaaatcttt tagcagttat gttatcctat tctagtttca aaacgctata
    27121 gaagcagcat tgtgctagtc tagattcagt ttactatact aaaacgagta gcttgaaatc
    27181 aaaaaaccca ccctcacagg caggttttat ctgtattatt cagctagatt atgctttacc
    27241 ttctgaaccg aatacgtcga tacgttcttc aaccgatgct tggatagctt ttacaccgtc
    27301 agccaagaat ttacgtgggt cgaagagttt tttcttgtcg tattctgctt cgtttgcttc
    27361 gtagtcacga gcaaatttac gagttgcgtt agcgaatgcg atttggcatt ctgtgttaac
    27421 gttaactttg gcaacaccaa gtttgatagc tgcttggatt tgctcatcag gaatacctga
    27481 tccaccgtgc aatacgattg ggaatcctgg aagagcttct gtcaattttt gcaagtggtc
    27541 aaggtcaaga ccttcccagt ttactgggta aggaccgtgg atgttaccga taccagctgc
    27601 caagaagtcg ataccagttt caaccattgc tttagcgtct tcgattggag ccaattcacc
    27661 tttaccgatg attccgtctt cttcaccacc gatagtacca acttcagctt ctactgagat
    27721 acctttagcg tgtgcttttt caacaacttc tttagccaat ttaaggtttt cttcaactgg
    27781 aaggtgtgaa ccgtcaaaca tgattgaagt ataaccaact tcgatacact caagtgcatc
    27841 ttcgtagtga ccgtggtcaa ggtggatagc tactggtaca gtgataccca ttgattcaac
    27901 aaggttagcg atcaagttgc gagcaacttt gtaaccaccc atgtatttag cagcacccat
    27961 tgaagtttgg atcaaaactg gagctttttt agcttctgct gcgcgcaaga tagcttgagt
    28021 ccactcaagg ttgtttgtgt taaatccacc aactgcataa ccgttgtcac gggctgcttg
    28081 gacaaatttt tctgctgaaa cgattgccat tttatcaggc ctcctctata tttttatggg
    28141 tcatcccatt tacattgttc attttatcac tttttgccaa aaaaatctag tttttcccgc
    28201 agtttcgatt gattttcttc taactccatc tatgtaaacc ctttctctcc ctagtcttgg
    28261 acgacttttg gaaaatctat aaagaaggtt aaacgattct cctccatctc gaaacgataa
    28321 gctaattttt catgttctaa tagactctta accacaaaga gccccatacc agaccccttg
    28381 accttgcgac tagcattgtc agaaaaagac tgggctagtt tttcttgttc ctctgagcta
    28441 cagctatttt cgataaaaag ttctccttct ctttctccaa ttcgaactaa gccacctgga
    28501 acagagtgct taatggcatt gctgatgaga ttagaaagaa tcaacttcat aactgatggg
    28561 tttagataag cctgctgatg ggtcaaacta ttgtctatct ggagctctct ttcctttgct
    28621 agcaaggcat aatctttgac cagattttgc gtcatctgga ggaggtcaat tgtttcccta
    28681 tcatctcgca attcctgcac agaagagagg gaaagtatct gcagaacatg gtgattgagt
    28741 tcatccacaa tccccaaggc aactcccaga tactggtctc tatccttata acgaccgata
    28801 ttctctctca tattttcgat taggattttc aaactagcca gcggtgtttt caattcatga
    28861 gaagctcctc gtaggaattc gaccttcatc ttctccagct ggagaatggc ttcattcttt
    28921 tcatgcaagt ccgcaataac agtcaagaga tgctggtaga ggctattgat ttgttccttg
    28981 agattaccta tctcatcctt agaatccacg cgcaatcgca cttgggaatc caggtccatc
    29041 atccgacggg tcacccgctt gatttccaaa atcggtgcaa caatagtccg agcgtagatg
    29101 taggccacca agagggaaat cagaaaggag gccagcaagg tatagggaag aaactggaga
    29161 ctgatttgct ccgcttcctt ttgtaaatcc atggaagcta gaaactggag aatcatagta
    29221 tcaccgtctt gcgttttcac ctcgcgctcc tcaataaaga gagaggttgt ctggcgatct
    29281 gtgtccagag gaagactgtc cttgacttct aacttgtcct cggtcatctc acctttgacg
    29341 gtccccttga tatcactagt ctgggaatac aagtctaaca cttgctcgat actctgccta
    29401 tctttccctt ctagggactg ggcaatggct gttgcctttt gaccaatggt ttcctgacga
    29461 tgactcagat aagtcgaagg aaaaagaaaa taaatagcta aatgaaggca gataaccaga
    29521 acactaaata tcgagaaggt atagataaat atctttgcaa ataaacctgt tcgtttcatt
    29581 ttcgctccaa tttataacca acattgcgca cagtgaggat acaatccaag tctagctttt
    29641 tccgcaattc cttgatataa acatcaataa cacggtcaaa gggaacctca tctgtcgctt
    29701 tccagacggc atcgataatc tgagaccgag tcaaggcccg gccttcattt ttcactagat
    29761 agtccagaat ttccaactct ttggcattga taggcacttc ttgacctgcg aggcttgcac
    29821 tgtagctttc aaagtccacc ttggtatcct tgtaagaaaa gattcgtcct gtatcgtagt
    29881 agcgcttgaa aatcgcgtcc accctcactt ttaagaggga gagggagaaa ggtttttcca
    29941 gatagccatc tgccaaagag gcaaaggcac tcatcttgta ttcctcatct tgaaaagctg
    30001 tcaacatcaa gacaggaacc tgactggttt tacgaatctc agctaggact tctaagccgt
    30061 tgagcttggg catctggata tccagtaaaa ccagggccac ctcatagcta gaaaattgct
    30121 ccagagcttc ctgaccgtcc gctgcctcaa tagtttcata gccacaatcc gtcaaataat
    30181 cactgacccc ctcacggatc atctcttcat cttctacaat taaaattttc atactttaac
    30241 tgctctctat tttttatttt tcttagaata aatacctact ctattttcta ttatagtctc
    30301 ttgctggcct tttgtctgta agtaactgat cactagataa aacgttgtga aattcctttc
    30361 tcataaattc catagcttta gtatattata tttaagcaat aaagtacaaa gaaaacaact
    30421 gaaagcaatg attttcacca ctgctttcgg atttattttg aattgttaaa tagccattcc
    30481 tatccactat tcttgaatag aaacacaaga tgcaatcttt attccagact cattttttca
    30541 aatttattca ccatccagca agagctcttt tggttgtttt ctaaggagat tgcttgaagc
    30601 aagcgccata acgagaacca ctagaaccaa ggcaaggaca aaaatgatga taaagtctga
    30661 tgtctgaata gaaatgtcta ggctcgacaa ggtcttgcta aagccatcta cttctgcacc
    30721 accaccaagg ttagaggctt gagccgcctt actagcctgt ttggcaacac ctgaagtcac
    30781 attggcaagg acagtgtttc caattgcacg ggcagtgtaa ttagctagga agtaagcaga
    30841 aactagagca gggatagcaa tcaagataga ttcggtgatg aattgaccca agatacttgc
    30901 ctgcttgagg ccgatagaga ggagaattcc cacttccttg cgacgggcgt tgatccaaag
    30961 gctgagcaag agggcaagga ggagaactga gaagctcaag ctaccccaga agaggaggtt
    31021 ggccatcttg tacataccag agatagattg ctcaagagct gggtagttag aggagctctt
    31081 gacgagtgtg tagctcttcc agttgatacc actgatgcca ttcaactctt tcataacatc
    31141 atccaagttc ttgtctgctg ttacaaagaa ggttgcgtcc ccataaatgg ctgtgtcttc
    31201 tgtgtatcca taaagttttg cagcagtgtg aatgtctgta atagctgtgt tttcgtaaag
    31261 ttcttgtgag taggttactg ctgacttatt atgaccatca aagagtccct tgattgtcac
    31321 ttcaactgtt tccttggctc ctttttcatt atctgcatcg tagatattag agtccagttt
    31381 aaccttgtcc cctactttcc agccgtgttt ggctgccaag tccttgtgca agaggatttt
    31441 atccttgtcg tcgttggtta agtgctctcc ttcgactagt ttataagaac cagagacaaa
    31501 cttgtcttct ttagaggagt cattgacacc tgtaatcatc aagctacttc caaaacgttt
    31561 ggcacgatca gcagtgagat tcttcttggt ttctggcgtt tcaatcaggt catatccagt
    31621 caaatctccg atagcgttga tacgtttgac ataagactca atggccttgt tttcggtgat
    31681 ttttttgatg tcttcaccct tgatattccc agcaccgcga ggcgttcctt ggttgacgcg
    31741 acgattgatt tgcatggaga agctattggt gatattttta aaggtctcct gagaagcctt
    31801 ggcagtagct cccttgattg acaagccgac caaactcaag ctcgccatga ggagaataat
    31861 caggaagatg acaatcgatt tgaaaaactt ccttgtaaca taggcaaatg cgttgtgtaa
    31921 catagattcc ctttctagat tttgttttaa tcattctatt aaaataagct caaattattt
    31981 actagtattg cgcgtttcag tcagtttctt atcctttaat tcaagtgtaa tatctgacgc
    32041 ttgtgccact tctttactgt gagttacgac aatcacacat ttacctgctt tctgggcaag
    32101 tgatttgagt agttcgacaa tatctccagc agttttagga tccagatttc ctgttggctc
    32161 atcagctaga ataactggag cttctgagac caaactgcga gcaatggcaa cacgttgctg
    32221 ttgaccacct gataactgga gaacattccg cttgatctgg ctttcatcca aaccaagctc
    32281 aagaagtgta ttcttgcttg cctttttgtt gaccaatcgg atattttcca gcggagaaag
    32341 ataatctatc aagttataat tttgaaagac cagggaaata tggtgcatgc gatggtaaga
    32401 atagcccttc ttacgaatat cctctccttg aaaaaggata gaaccttcaa caggactatc
    32461 tagaccagca agtagggaca agagtgtgga ttttcctgct cctgactccc caataatact
    32521 gtaaaatttt ccgggttcaa aattataatt gatctgatat aggactgctt cagcagtatt
    32581 cttataacgg taggtaacat cttgtaattg taataaagtc atgatttctc cttcttaact
    32641 aatagatgat aaaatttctt tcggtgattt tctaaataag aataggaaac aaagggctac
    32701 agataagcaa ctaagcagaa ctagaaaaac ataggattct gcaaaagata agatgctagt
    32761 tgataaactg cttgctttgg ctagtgtatc ttgtaagctt gcctgatctc cacttgctag
    32821 tagagtttgg agtaggtaac ttgtgattgc gtttcctgca acaaatgctg gaagcaaagc
    32881 tccaagagat accaaaacta cctctaaaca gaattgtagg aagatcgagc tcttgccttt
    32941 tccaagtgca agtaaaatcc ccacttcata gacccgttct ctcaaccaga gagacaaaac
    33001 cagaattaag gctccagctc ctgctatcaa catcccataa aggaagatgg tcaggaaggt
    33061 ttggaaagtt gcaactgagt ctttgatttg ttcaaaagcc ttgttttcct tttcgacttg
    33121 gtagccttga ttttccaagg ccaagttttc tacctgcttc atgagtccgt ccatttcctt
    33181 aggattttct acatagaagc gtgctgcact gacttgagct tcactattgc ccaaaagggt
    33241 ttggctactt tcatagtctg taaagacttg attttcactg aagtcagaag acaagcctgt
    33301 gaatttctct tgttttttac cagaaaagat gccgataatc tcaaactcta ctgtttgtcc
    33361 ttttccagat tcagactgac cagcatccaa gccaatcttg tcatgaagcg aaagaccgtt
    33421 cttcttagcc aattcttcgt ggataaggat tttcttggaa tccccttttt gaaggtgtcg
    33481 cccttctttt agattgaaag ccgaactggt aaaggttaca tccttggatg aatcctcaag
    33541 agccgttaag ctaaccaagt tattgtctgc agctgataaa tcatcacgct ccacgctctg
    33601 ctcgccagtc actgcttcct tgtcttttag ttttgcgacc gtctcaagtt caggagagac
    33661 attttccaac cccttaatct tgcttacaga tgctaggtct gacaacttga atgtctgacc
    33721 attctctatc ttcttaatag aaaaagatgt attgagtgat ttataaagat tgctttctac
    33781 tgttttgttg gacttcatca gagtcaaaca ggctgaaatt ccggccaata agaccaataa
    33841 aatcagaaat aaaataaaac ttctcagtcg ctttctgctg acataagccc aagatctttg
    33901 gattggattc atttgtcacc tccatatttg taagactatt ataaaaccca aatatgaaat
    33961 gtttatgaaa tacgaaaaaa aaatatcgag taggggataa tctctagccc ctctcacacc
    34021 acc
//
LOCUS       DAVLUM010000018        33954 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLUM010000018 DAVLUM010000000
VERSION     DAVLUM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.018"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            331..507
                     /locus_tag="VYN42_000708"
     CDS             331..507
                     /locus_tag="VYN42_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461816.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            909..3122
                     /locus_tag="VYN42_000709"
     CDS             909..3122
                     /locus_tag="VYN42_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1461817.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNFLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSRDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(3344..3820)
                     /locus_tag="VYN42_000710"
     CDS             complement(3344..3820)
                     /locus_tag="VYN42_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1461818.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            4043..7246
                     /locus_tag="VYN42_000711"
     CDS             4043..7246
                     /locus_tag="VYN42_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1461819.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSTWVDQKNSSADASTRVIEAKGG
                     AITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WLHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKGINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            7599..7984
                     /gene="tnpA"
                     /locus_tag="VYN42_000712"
                     /pseudo
     CDS             7599..7984
                     /gene="tnpA"
                     /locus_tag="VYN42_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(8363..8992)
                     /locus_tag="VYN42_000713"
     CDS             complement(8363..8992)
                     /locus_tag="VYN42_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1461820.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(9002..10003)
                     /locus_tag="VYN42_000714"
     CDS             complement(9002..10003)
                     /locus_tag="VYN42_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1461821.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(10034..10675)
                     /locus_tag="VYN42_000715"
     CDS             complement(10034..10675)
                     /locus_tag="VYN42_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1461822.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAMDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(10694..11509)
                     /locus_tag="VYN42_000716"
     CDS             complement(10694..11509)
                     /locus_tag="VYN42_000716"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1461823.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            11781..12215
                     /locus_tag="VYN42_000717"
     CDS             11781..12215
                     /locus_tag="VYN42_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1461824.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            12227..13417
                     /locus_tag="VYN42_000718"
     CDS             12227..13417
                     /locus_tag="VYN42_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV1461825.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            13428..13919
                     /locus_tag="VYN42_000719"
     CDS             13428..13919
                     /locus_tag="VYN42_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1461826.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            13934..14713
                     /locus_tag="VYN42_000720"
     CDS             13934..14713
                     /locus_tag="VYN42_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1461827.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            14700..15518
                     /locus_tag="VYN42_000721"
     CDS             14700..15518
                     /locus_tag="VYN42_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1461828.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            15518..15811
                     /locus_tag="VYN42_000722"
     CDS             15518..15811
                     /locus_tag="VYN42_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1461829.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            15833..17734
                     /locus_tag="VYN42_000723"
                     /pseudo
     CDS             15833..17734
                     /locus_tag="VYN42_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
     gene            17794..18795
                     /locus_tag="VYN42_000724"
     CDS             17794..18795
                     /locus_tag="VYN42_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1461830.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(18905..19240)
                     /locus_tag="VYN42_000725"
     CDS             complement(18905..19240)
                     /locus_tag="VYN42_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461831.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(19251..19493)
                     /locus_tag="VYN42_000726"
     CDS             complement(19251..19493)
                     /locus_tag="VYN42_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461832.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(19504..20046)
                     /locus_tag="VYN42_000727"
     CDS             complement(19504..20046)
                     /locus_tag="VYN42_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1461833.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(20062..20256)
                     /locus_tag="VYN42_000728"
     CDS             complement(20062..20256)
                     /locus_tag="VYN42_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1461834.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            20422..21372
                     /gene="rsmH"
                     /locus_tag="VYN42_000729"
     CDS             20422..21372
                     /gene="rsmH"
                     /locus_tag="VYN42_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1461835.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLARIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            21384..21701
                     /gene="ftsL"
                     /locus_tag="VYN42_000730"
     CDS             21384..21701
                     /gene="ftsL"
                     /locus_tag="VYN42_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1461836.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            21705..23957
                     /gene="pbpX"
                     /locus_tag="VYN42_000731"
     CDS             21705..23957
                     /gene="pbpX"
                     /locus_tag="VYN42_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1461837.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            23959..24939
                     /locus_tag="VYN42_000732"
     CDS             23959..24939
                     /locus_tag="VYN42_000732"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1461838.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            25548..27653
                     /locus_tag="VYN42_000733"
     CDS             25548..27653
                     /locus_tag="VYN42_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1461839.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYRSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLNPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            28105..28440
                     /locus_tag="VYN42_000734"
                     /pseudo
     CDS             28105..28440
                     /locus_tag="VYN42_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(28507..28989)
                     /locus_tag="VYN42_000735"
     CDS             complement(28507..28989)
                     /locus_tag="VYN42_000735"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1461840.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEEVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(29084..30568)
                     /locus_tag="VYN42_000736"
     CDS             complement(29084..30568)
                     /locus_tag="VYN42_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1461841.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTGRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDATRAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            30721..32331
                     /locus_tag="VYN42_000737"
     CDS             30721..32331
                     /locus_tag="VYN42_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1461842.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGAKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVEMTD"
     gene            complement(32475..33873)
                     /locus_tag="VYN42_000738"
                     /pseudo
     CDS             complement(32475..33873)
                     /locus_tag="VYN42_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
BASE COUNT        10313 a         5988 c         7583 g        10070 t
ORIGIN      
        1 tgttaacatt agcagtgaag agatcttttt aagatattct tctctgcttt ttcattttat
       61 ttttttgcta tgtagggtat gaagcaaaat agaaagtagt tcgaatagtt gataaacagg
      121 gaactgctgt tatttaaaaa aacaataaag taaagtatgt tatcgtagaa tacgatacaa
      181 tagtaaaaaa gcaaaaagaa tgcgttttat atttgggttt gaggcttata aaataggata
      241 agcgtgctga aaacttagat atgacaaaca aaataaaatt tttaaaagct acagagaaac
      301 atggtataat gtatctaaag gaggtagcat atgtccttag atatagataa agaaaagatg
      361 acaatcatgg gaatagcttt tgaaaaccga tccgttttta agagtgtttg gtatgcttta
      421 agtacaaata tgattgaagg atggcgacct acggttagtg atgttgaaaa attacgagat
      481 gaagctcttg ctctggggat gacttaatga agcgcaactg ttatgaatct tatgactatg
      541 ttgatccgga taatttatat accgatccgg gttcttcagt tctaagaaat aagcaggaag
      601 gaaaaaagca cgcgagcttg aatatcgtat gattgctagt aagagtttga aattatttat
      661 caatcctatc ttagttaata gtttaaaagt agtttgtttc acaactgcat aagcttagaa
      721 aagttgaaaa gtgataactc tttaataaac tcttggtttg ttaaaagata ttttgtccac
      781 tacatttttt tcaattgact attatttgtc atagatataa cagatagaac attgcattca
      841 gaataatgaa aaacgcatca aaaatggtgc gttctgtttt tatgctacca taaaaggagg
      901 aaaacaaatt gaaaattttt aagggagagt tttatcgaat ctctgtatta acagacaagc
      961 tagtaaggtt agaatactct cgaactggaa attttgagga tagaacgaca caacttatct
     1021 ataatagaga ttttggccaa atttcgttag attatatcga gacatcaaat gtactagata
     1081 ttatgacgga ctattttcat ctgcacttta ataaaggaga atttaacgcc gaaaatttat
     1141 ttatagaatt aaaaggaaat tttgccgtat atggtagtcg ctggtatttt ggtgaatcta
     1201 ttgaaacgtt aaaaggaaca gctcggactc tggataaggc agatggagca atctcgttag
     1261 aagatggaat tattagccga aatggtatag ccttattgga tgattctcaa ggatttattt
     1321 gggatgaaca atctggttat attgagagag aaaatcaaat tgacctgtat ttctttgcct
     1381 atgggcatga ttatagagga gcaatcagag acttttacca tttgactggt tcaacaccct
     1441 tgttgccaag atatgcttta ggcaattggt ggagtagata ttggccttat acgtcggatg
     1501 aatacttgga tttaatagac agatttgaaa cagagaaaat tccattatct atcggtgtgt
     1561 tagatatgga ttggcatata actgacattc cagctcgttt tggaagtggc tggacaggat
     1621 atagttggaa tagaaactta ataccaaatc cagaacagtt attgcaacaa cttcatgata
     1681 gaaagttaaa actctcctta aatgtccatc ctgctgatgg gatacgggct tatgaagaag
     1741 cttatcctca aatcgcaaaa cggttggggt taaatgtaga actagaagaa cctgctattt
     1801 ttgatttttt taatccctct tttagggaag cctactttaa agatgttcat tatgagctag
     1861 aaaagcaggg agtagatttt tggtggattg actggcaaca agggacacaa ggtatgctag
     1921 atccactttg gcttttaaac cattatcact atcaggatag ttgtaaaaat gcagaaggtg
     1981 gtttgatttt atcaagatat gcaggtcctg gtagtcaccg ctaccctgtt ggtttttcag
     2041 gggatactat tattagttgg aatttcttaa ggtttcaacc ctattttaca gcgacagcat
     2101 ctaatatcgg ttatagttgg tggagtcatg atatcggtgg acatatgttg ggggattatg
     2161 acgaagagct acaaactaga tggctacagt ttggtgtttt tagtccgatt actcgattac
     2221 atagttctag aagtcctttt aatagtaaag aaccttggtt cttttcagaa acaacatcta
     2281 agattatgaa gaaatacctt cgtttgagac atcagatgat tccctatcta tataccatga
     2341 atgtaaagac acatgaggaa ggtgccccat taatcagtcc aatctattat ttctatccag
     2401 agaatgatga gagctataat gttccaaacc aatacttttt tggaacagaa ctgatggtgg
     2461 ctcccattgt agaaaagatg gatttgacat tccaatctgc aaaagtagat gtatggttcc
     2521 ctgaaggtga atggtatgac ttcttttcag agaaaaaata cacaggtggt gtgaagttaa
     2581 gtgtttatag ggacatctcg actacgcctg tgtttgcaaa aagtggtgca atcattccct
     2641 tggttggttc tgagataggt atgggtgttg atttacctga ggttgtagat tggtatgtat
     2701 tcccaggcaa acaacattct tttgaaatgc ttgaagatca aaatggtcaa agatataaaa
     2761 caagattatc aatcgattgg gaaatgggaa tggtagagtt agcattacaa ggagattcta
     2821 gtatcgttcc aagcaataga aaacatagaa ttcattttaa aggaacgaat gtgtctataa
     2881 ttgaattgcc aaataagaat gatacagcta aatttgaatg gaaagataat aaaaggacat
     2941 ctttaaatga cgaagttttt agactactaa agacagcttc tcttccatat gaattaaaag
     3001 atagattgtt aaatcaattc atcaatgcga aaaactctcg tgacttaatg aatatcttgc
     3061 atcatcagga taaggaattg agagggcgtt tgttggaaat gatatttact agccaaaact
     3121 aattgaaata attagaaagt catttgttta gtgtatatga agattctgta tggtattcgt
     3181 tatcactggt cacattgaaa ttgtgaaata agcacctaca acatagactt tacaacactt
     3241 catgtttcat atcatggggt gtttttctat ttaagtcaaa gcccatcaaa aaatctcact
     3301 attcatcagg ttaaaggaaa cctaatcata gtgagattgt gaattatagt agagtttgta
     3361 tcgcctcttc aatttgtttt gggtctgttt ttgaagaaaa gcgttcaaag acttgcccat
     3421 ctcgaccgat gagaaactta gcgaaattcc attcgactcg ttttcctagt gggccggatt
     3481 tctggtcttt taaccagaca tagagagggt ctgcttcctt accgttgacc ttaatcttgg
     3541 caaaacgtgg gaaggtggtt tgaaaatgta ggctacagaa ggcgttgatt tcctctgcgc
     3601 tgccgggtgc ttgtcccata aactgattgc aagggaaatc caatatttca aagccctgat
     3661 cttgatagcg ttcatagagt tcttgaagtc cctggtactg gggcgttaaa ccacatccag
     3721 tagcagtgtt gacaatcaag agaactttac cacgatagct atccaaggga gttgcttggt
     3781 tgttttggtt caaaacggaa aaatcataaa gtgaagtcat gagggcctct tttctttttc
     3841 tacattgtaa cagtttttac ttttttcgtc gagtcggatg gaagatattg ttgaagaata
     3901 agccttcaat atgatagaaa ccgtttacaa ataactttaa aaatggtatg atttaattaa
     3961 accggtttac tttgttgcta taaatctcta atttgagatt tagttcctat tgattttaca
     4021 atatgtttat tggagtgtat acatgcaaac aaaaacaaag aagctcattg tgagtttgtc
     4081 ttcacttgtt ttatcaggat ttttattaaa ccattatatg acagttggag cggaagaaac
     4141 gactacgaat accattcagc aaagccagaa ggaagttcag tatcagcaaa gggatacaaa
     4201 aaatttagtt gaaaatggtg attttggtca gacggaggac ggaagcagtc cgtggacagg
     4261 aagcaaagct caggggtggt caacttgggt agaccagaag aatagttctg cagatgcctc
     4321 aactcgagtc attgaggcta agggtggggc tatcactatc tcaagccatg agaaattaag
     4381 ggcagcggtt caccgtatgg ttcctattga agctaagaaa aagtataaac tgcgtttcaa
     4441 gattaaaaca gatcataaag tcgggattgc caaggttcgt atcattgagg aaagtggtaa
     4501 ggacaagcga ttgtggaatt ctgcaacgac gtcaggaaca aaggactggc agaccattga
     4561 agcagactat agcccgactt tagatgttga taaaatcaag ctggagttat tctatgaaac
     4621 aggaactggg actgtttcct ttaaggatat tgagctggta gaggtagcag accagctttc
     4681 tgaggattct caaacagata aacagcttga ggaaaagatt gatttaccaa ttggaaaaaa
     4741 acatgttttt tctcttgcgg actatactta taaggtagaa aatcctgacg ttgcttcagt
     4801 caaaaatgga attttagaac ctcttaagga agggacaacc aatgtcattg tcagtaaaga
     4861 tggcaaggaa gtgaaaaaga ttcctttgaa gattctagcc tctgttaagg atgcatacac
     4921 agcccgtttg gatgactgga atggcatcat cgctgggaat caatactatg attctaaaaa
     4981 tgaacagatg gccaaattaa accaggaatt ggaaggaaag gtagctgata gcctatctag
     5041 tatttcaagt caggcggacc gcacctattt gtgggaaaaa ttttcaaatt ataaaatgtc
     5101 tgcaaatctg actgccactt atcggaaatt ggaggagatg gccaagcaag tgaccaatcc
     5161 ttcttctcgt tattatcaag atgaaactgt cgttcgaaca gtcagggatt ccatggaatg
     5221 gctgcataaa catgtctaca atagtgaaaa gagcattgtt gggaactggt gggattatga
     5281 gatcggtaca cctcgtgcca tcaacaatac cttgtctctg atgaaagaat acttctctga
     5341 tgaggaaatt aaaaaatata cagatgtaat tgaaaaattt gtaccagacc ccgaacattt
     5401 ccgaaagacg actgataacc catttaaggc tctaggtgga aacttagttg atatgggaag
     5461 agtaaaagta atagctggtt tactgcgtaa agatgatcaa gaaatttctt ctaccattcg
     5521 ctcgattgag caagtgttca agttggtaga ccaaggtgaa ggtttttatc aagatggatc
     5581 ctatatcgac cacaccaatg ttgcctatac gggtgcttat gggaatgttt tgattgatgg
     5641 cctgtctcaa ctgttgccag tcattcaaaa gaccaagagt ccaatcgata aagataaaat
     5701 gcaaaccatg taccactgga ttgataaatc gtttgctcct ttgctggtga atggagaact
     5761 gatggatatg agtcgtggac gctcgatcag tcgtgcaaat agcgaggggc acgtggccgc
     5821 agtagaagta ctaagaggga ttcaccgaat agcggatatg tctgaaggag aaaccaaaca
     5881 acgtttgcag agtcttgtga agaccattgt tcaatcggat agttattatg atgtctttaa
     5941 gaatttgaag acttataagg atatcagttt gatgcaatcc ttgttaagtg atgcaggagt
     6001 cgcaagtgtt ccaagaccaa gttacctatc tgcctttaac aagatggata aaacagccat
     6061 gtacaatgca gagaaagggt ttggatttgg cttgtcactc ttttccagtc gtaccttgaa
     6121 ttacgaacac atgaacaagg aaaataaacg tggttggtat acgagtgatg ggatgttcta
     6181 tctttacaat ggcgatttga gtcactatag cgatggctac tggccaacag ttaatccata
     6241 taagatgcct ggtacaacag agacggatgc taagagagcg gatagcgata caggtaaagt
     6301 tttaccgtct gctttcgttg gaacgagcaa actagatgat gccaatgcga cagcaaccat
     6361 ggatttcacc aactggaatc aaacattgac tgctcataag agctggttta tgctaaagga
     6421 taagattgcc tttttaggaa gcaatatcca aaacacttca acagatactg ctgcaactac
     6481 aatcgaccag agaaaactgg aatcaagtaa tccatataaa gtctatgtca atgataaaga
     6541 agcctccctt acagaacaag aaaaggatta tcctgaaacc caaagtgtct ttttagaatc
     6601 gtccgattcg aaaaagaata ttggttactt tttctttaag aagagttcaa tcagcatgag
     6661 taaggctttg caaaagggag cctggaaggg tatcaatgaa ggacagtcag acaaggaagt
     6721 tgaaaatgaa tttcttacga ttagtcaggc tcataagcaa aatggagatt cttatggcta
     6781 tatgctcatt cctaacgtgg atcgtgccac cttcaatcaa atgataaaag agttagaaag
     6841 tagcctcatc gaaaataacg aaacccttca gtctgtttat gatgctaaac aaggagtttg
     6901 gggcattgtg aaatatgatg attctgtctc tactatttcc aaccaattcc aagttttgaa
     6961 acgtggagtc tataccattc gaaaagaagg ggatgaatat aagattgcct actataatcc
     7021 tgaaacccag gaatcagctc cagatcagga agtctttaaa aagctagagc aagcagctca
     7081 gccacaagta cagaattcaa aagaaaagga aaaatctgaa gaggaaaaga accattcgga
     7141 tcaaaagaat ctccctcaga caggagaagg tcagtcaatc ttggcaagtc tagggttctt
     7201 gctacttggg gcattttatc tattccgtag aggaaagaac aactaatttg ttcatcatct
     7261 agatgaatta catgaaactg tggaaaatag aaaaaatccg aagaaggcca aatatcttcg
     7321 gatttttctt ttaaaaaagg ataagttgat acttatcctt ttttacttca ttattatgtg
     7381 actatagcgt tttgaaacta gaatagaacg ttataactgc taaaagattt ctataaattc
     7441 atttgatttt cctaatcaat ttgttcgtat cctatttcac tccactatat aagtccgtct
     7501 cgctccgtga ggtgcgcgtc gaaggttata ccaaaaaaac tccaaacgcg atacaataaa
     7561 ggtattcaat ccaattgtaa agcgaaagga gaaaaaatat ggcacaaaag actcatagtt
     7621 tatcatacac aaagtggatg tgttctatca tattgtgttc acccctaagt atagacgaaa
     7681 agtcatctat aatcaatata gaagtagttt aggcgaaata tttcatcgct tgtgtagtta
     7741 taaaggtgtt gaaatgatcg agggtcactt aatgccagac catgtacaca tgttagtcag
     7801 tattccacta aggctaagtg tttcaagttt tatggggtat ttaaaaggca aaagtgcact
     7861 catgatgttt gacaaacacg ccaatctcaa gtacaagttt gggaatcggc atttctgggc
     7921 ggaaggttat tatgtaagta cagtagggct taatgaagcc acaattaaga aatatagtca
     7981 agattaaaga aattatcgag tggatgattt cttcacgagt atgaaaattt gagaactagt
     8041 aaagtatgat atatagtaaa atgaaataag aacaggacaa aatcgatcag gacagtcaaa
     8101 tcgattttta acaatgtttt agaagtagag gtatactatt ccagtttcaa tctactatag
     8161 cactagataa attgagtgta aaagaatatg aggatccctt tagggatagt ggtaagtaat
     8221 accaaagtct cttaaagagg caagtgacga gtcaagagca ataaggcttg aacaacgtga
     8281 aagccagcgt ctttaggcgc tggctgatga tttgggctta tagctctgag ataaaccacc
     8341 cgttagacgg gtagttatga ttttatctga gtgtaatata ctgttgggca atctcgctga
     8401 tgcggtcaaa gttgccttgg gaagcgagtt tattgagttc gccaccaatt ccaacggcgt
     8461 ctgcaccagc agcgaaccat tgagggatgt tgtttagacc gactcctccg gttaccatta
     8521 cggaaacttg tgggatcggt gccttgactg cagagatata tgctggactg agagcactac
     8581 ctgggaagag tttgatgatt tcactaccgg cttcaagtgc agtcgtgatc tctgtgaggg
     8641 taatacagcc tggaatgtac ggtgtgctgt agagattgca cattttcgca gtttcagcat
     8701 ggaaagatgg agaaacaacg taatttgctc cggctagaat ggcatctcta gcagttacgg
     8761 catcaagcac agtacctgca ccgatacaaa cactctgatc gtcctgatac aagtctacaa
     8821 gttccttgat gatttgtcct gcatactgat tggtataggc gatttcaata gctttgatac
     8881 cgcccttgat acaagcaatc gaggcttgca gtccttcttc ctttgtattt cctcgaatga
     8941 cagcgacaat tttctgtttt tttagttcaa taatcgtatc tgatttggtc atgtaattct
     9001 cctaacgaat gatatcttgt gcatttgcca gtaaattttc aatactagtt gcggaagtgg
     9061 agagatggtc tcctggaaga gtgcatttga gagttgcgct cgcaactgca aagtcaatgg
     9121 tagtttttag ggaggaatga tggagtagtt ggtaaagggc accagatata aaggcatccc
     9181 cgctaccaat tcgttgatag actgcagttt ttagttggac agactcttca aatcgttctt
     9241 ccagagcata ggcttgatag acatttttgt cttgctcatc actagagcgg agggtatgga
     9301 aaatggcctt gaaaccatag gcttctttta aaagtcgcat gcgattttcc acctcttcta
     9361 ggctagcact gtctcttgga aacatctcta gattttggtc atcaatcatg agaggatcaa
     9421 taccgaagca atagtcagta aaacgtgcaa acttagaaaa ttcatacttg gcttctagga
     9481 ctgaaatcat ctttgttctc agattgagat ccattgaaac gacaattcct cggcgcttgg
     9541 cttcttccaa gagtaggaga aggatcgcac ggacctcttg accgatagct acggtgattc
     9601 cactaaaatg aaaatggcta atcccctgaa agagagaatc catatctagc atgtttggcc
     9661 gaatctggct gatacttgta tgcttacgat cgtagaaaac ttcactttga cgacaaccaa
     9721 agccgttctc caaatagtag aggccgattc gatcgccaag ccgacagatt gaactggtat
     9781 cgatttggtg ctgtttcaag aatgtgagaa aacgatctcc aatctcgttg gcagggagtg
     9841 cggtaaagac tttcgttgag atacccaggg cttgcaaatt acaagcgatg ttaatttctg
     9901 atccgccaaa ataagtcgaa ctggcaacat gatcgccgat actggtggca tctaatggtg
     9961 agattcgaat taatggttcg ccaaacagta atattttcgt catccattag ttcctttctg
    10021 gtttagaata gctttacttg gctaatactt ctttcaaata agcagcgact tcatcatctt
    10081 ggcagttttc aaagaagtat tcttggaaat atttgccaga gatggtgtct ttgaggaagt
    10141 cttggtcgat tgttttaagg atggtcatca aatcattgtg ggtgatttgt ttcacctcgt
    10201 ttaagatacg agcgttgcgt tgttcaggga ttacacgttc tcttgggtag ccaccgccca
    10261 tttcttcagc aaataagcgt tcaaacatca atttgagggt cagttctgcc ccccagccaa
    10321 atcctttggc ataagggata gacaaggcgt taccaccatt gatttgagaa taaaggtaag
    10381 cgtcagttgg gtccattgct agaccacaga caacaccagg gaagctgttt aaagcaagca
    10441 tagcccctac acccgtacca cagccggtaa caacaaagtc aactgccttt gtatttaaaa
    10501 ggatggcagc cattagtccg ttctgcacat aagttaattg actttctcct tcttctccac
    10561 gcataccata gttaaataat tggtagtctt ttttatctgt cgcttctttt agactatcgt
    10621 aaataatgtg attcttgcta gcttgactat tttcattgat taatgcgatt ttcataagat
    10681 cttctttcta tttttactca ggttgttttc cgatgtaggc taagataccg ccatctacat
    10741 ataggatgtg gccattgaca aaattgctgg catcactagc gagaaagaca gcagggccca
    10801 tcaaatcttc aggatttccc caacgtgcag caggtgtttt tgcaatgatg aactggtcaa
    10861 atgggtggcg agaaccatct tcttgcaact cacgaagagg tgctgtttga ggagtggcaa
    10921 tataacccgg tccaattccg ttacattgga tattggctcc accgtattca gacgcaatgt
    10981 tgcgggtcaa cattttcaag ccccctttag cagcagcata agcgctaact gtttcacgtc
    11041 ccagttcgct catcatcgaa caaatattga taatctttcc atgccctttc tttatcatag
    11101 aaggaataac tgcctttgaa acgataaatg gtgcgtttaa gtcaatatcg atgaccttac
    11161 ggaaatcagc ggcgctcatt tcgcacattg gaactcggcg gataatacca gcgttattaa
    11221 cgaggatgtc aatgacacca acctcttgtt cgatttgctt gaccatggct tggataccgt
    11281 cctcgtctgt cacgtcacag acatatccat gggcttggat gccaacttca cgataagctt
    11341 caatcccttt attgaccaga tcttgattga tatcgttaaa gacaatagta gcgccggctt
    11401 cagcgtagga tttggcaata gcaaatccaa ttccataaga agcgccggtg atgagagcaa
    11461 tttttccttt taaagaaaac tgctcaattg agaatgatgt atttgtcatt tgatacttcc
    11521 tttcaaattt gttaagactt ctctataacc aaattatatt ctagtaaacc ggttttgtca
    11581 ataaataaat atttttattt ataaaaagat ttattttcct aaaaaaacgg aagattttga
    11641 aatttctgtc tattaaactg gttaaaaaga taatgaaagc gctaatattt ttttaaaaaa
    11701 actattgaca agataaaaat aaaggattac aatggggaat ataaagtaaa ccggtaaacc
    11761 taaacaagaa aggagaaaag atgaaaattg tacttgtagg gcatggacat tttgctacag
    11821 ggatttatag ttctttacaa ttgattgcag gcaatcaaga aaatgtggag gcgattgact
    11881 ttgtggaagg aatgtcagca gatgaactca agcaaaaaat cttacttgca atttcaaatg
    11941 aagaagaagt tttaatccta agtgatctct tgggaggatc gccattcaag gtttcttcta
    12001 ccataatggg agaaaatcca gccaaaacaa tgaatgttct ctcgggtttg aacttagcca
    12061 tgttaatgga agcagtcttt gctagaatgg ctcatagctt tgatgaagtt gttaataaat
    12121 cagtagtggc ggcccagggc ggagtcgtaa atggtaaaga attgttttca acggatgcag
    12181 aggaagagga agaagatttc gaatcgggta tttaaagggt aaaagaatga taaaaaaggt
    12241 tacgattgaa aaaataaaat cgcctgagcg cttcttagaa gtaccacttc tgacgaaaga
    12301 agaagtcggc caggcaatcg ataaggttat tcggcagtta gaactcaacc ttgactattt
    12361 caaggaagat ttcccgacgc cagctacctt tgataatgtc tatccaatca tggataacac
    12421 ggaatggacc aatggtttct ggacaggaga actgtggttg gcttatgaat acagtcaaca
    12481 ggatgcattt aaaaacatcg ctcataaaaa tgttctttct ttcctggatc gtgtcaataa
    12541 gagagtagaa ttggatcacc atgatctcgg cttcttgtac acaccgtctt gtatggctga
    12601 atataagata aatggagatg gagaggctag agaagcaacc ttgaaagctg cagataagtt
    12661 gattgaacgc tatcaagaaa aaggtggttt tattcaagct tggggagact tgggcaagaa
    12721 agagcattac cgtttgatta tcgactgctt gctcaatatc caactcttat tctttgctta
    12781 tcaagaaaca ggcgatcaaa aatactacga tattgcagaa agtcatttct atgcttcagc
    12841 taataatgta atccgtgatg acgcttcgtc cttccacacc ttctattttg atcctgagac
    12901 aggtcaaccc tttaaaggtg taacgagaca agggtatagt gatgattcat gctgggcacg
    12961 tggtcaatca tggggagtct atggtattcc tttgacttat cgtcacttaa aagacgagtc
    13021 ctgctttgac ttgtttaagg gtgtgaccaa ttatttcttg aatcgtctgc caaaagatca
    13081 tgtgtcctat tgggatttga tttttaatga tggtagtgct caatcacgag attcttcagc
    13141 aacagctatc gccgtctgtg ggattcatga aatgctaaaa catctcccag aggtggatgc
    13201 tgacaaagat atttataaac atgctatgca tgccatgctt cgttccttga tcgaacatta
    13261 tgcaaatgat caatttaccc ctggtgggac aagtctcctc cacggtgtgt actcatggca
    13321 ttcaggtaaa ggagtggatg aaggcaatat ctggggtgac tactattacc tagaagccct
    13381 tatccgtttc tacaaagact ggaacctata ttggtaggag gagaaatatg acaatgccaa
    13441 atattattat gacccgtatc gatgaacggt tgattcatgg gcaaggacaa ctttgggtaa
    13501 aatacctagg ttgtaatacg gtcattgttg ccaatgacga agtaagcaca gacaagatgc
    13561 aacaaactct gatgaaaaca gttgtgccag actcagttgc catgcgtttc ttccctttgc
    13621 aaaaggtgat tgatatcatt cacaaggcta atcctgctca aacgatcttt atcgttgtaa
    13681 aggatgtgaa ggacgcttta accttggtag aaggtggtgt ccctatcaaa gaaatcaata
    13741 ttgggaacat tcacaatgct actggtaaag agcaagtgac acgctccatc ttcctgggtg
    13801 aagaggacaa ggcggccctc aaggaattga gccaaactca tcaagtaaca tttaatacga
    13861 aaacaactcc aacaggaaat gatggagctg ttcaagtcaa cattatggac tatatttaaa
    13921 agaggagatc gttatgtcga ttaatgtatt tcaagcgatt ttaattggat tatggacagc
    13981 tttctgtttt agtggaatgc tgttaggaat ttacaccaat agatgtattg ttctgtcatt
    14041 tggtgtcgga attattctag gtgatttgcc tactgctctt gcaatgggag ctattggtga
    14101 attggcttat atgggattcg gtgttggtgc tggaggtact gttccaccaa acccaatcgg
    14161 acctggtatc tttggtacct tgatggctat cactagtgct ggtaaagtca gtccagaagc
    14221 ggctcttgcc ctctctactc cgattgctgt ggcgattcaa ttcttacaaa ctttcgccta
    14281 cactgtacgt gctggtgcgc ctgaaacggc gatgaagcac ttgaaaaacc ataatttgaa
    14341 gaaattcaag ttcactctaa atgcaacaat ttggttgttt gcctttattg gatttacctt
    14401 gggttgcttg ggtgcccttt caatggatac cttgttgaaa ctcgtagact acattccacc
    14461 agtattgctt acaggtttga cagttgctgg taaaatgctc ccagctatcg gttttgcgat
    14521 gatcttgtca gtgatggcta agaaagagtt gattcccttt gtcttgttgg gatatgtttg
    14581 tgcagcttat ctaaacatcc caacaattgg tattgcaatt gtaggtacta tctttgcttt
    14641 gattgaattt tataacaagc caaaaacagc ggatcatgtg gtagaggagg aagcacacga
    14701 tgactggatc taacaaatta acaaaacgtg attatcttaa aacgtctttg cgggcattct
    14761 tttgtcaaaa tggatttaac tatagtaact atcaagggtt gggatatgcc aatgtgatgt
    14821 atcctgcttt gaaaaaacac tatggagagg atcaggaagg tttctaccaa gccttggaag
    14881 aaaactgtga attctataat accaacccac acttcctgcc ttttattacc agcttgcatc
    14941 ttgtaatgtt ggaaaatggc cgaccaacaa aagaaacacg tagcatcaag atggccttga
    15001 tgggaccatt ggcaggtatt ggggattctc tttctcaatt ctgtttagct ccattgttct
    15061 caaccatcgc agcttcgttt gctcaagaag gcttggttgt cggtccaatc ttgttcttcc
    15121 ttgcgatgaa tacgatttta acagcgatta aattgtcaac tggtctgtat ggatacaaac
    15181 taggaacaac tgtgattgat aaactaagcg aacagatggc aacgatttct cgtattgcca
    15241 atattatcgg tgtaaccgta attgctggtt tggcagcgac atctgttaag attatggtgc
    15301 cgattacctt tgctgcaggg gaagttaaag cagacgctaa acaaagtatc gtaagtattc
    15361 agggaatgct tgataaggtt gctccagctc ttctaccagc cctatttaca cttttagttt
    15421 actacttgat caaagaaaag aaatggacaa catataaact cgttatttta acagttatca
    15481 tcggaattat cggaagctgg cttaagatta tagcttaatg gatacaacat tgttttatgg
    15541 aatagtgatt gtcttggcag tgagtcccct tttactgtca agctttcatt ctattcgtca
    15601 gcaaaagttg cttcgcaaac agatggagca acgacaagag tatttagctt ctttaacatc
    15661 tggtgatgaa gtgttgttat tgtctggaat tcatggaaaa atcatttcta tcaaagatga
    15721 cttggtctcc ttgcagattg caaaaggtgt ggtcatctat gtagaaaagg aaagtgtaat
    15781 gggaaagaca aaagaactgc tttttaagta gttctttttc tggtaataga taatgaaaga
    15841 agaaagaaga caattttttg aaagagtcga tggaaaccaa tgtcgtgatt atatcttgtc
    15901 ccactgctca aaagactatg agaaagtcaa gagttccctt gaacgcttga tggacaatcg
    15961 ttttatgttt gatagtcctt gggatatgga gccttgttca aaaatccatc aaatccagcc
    16021 gatggtatgg gatcaagtat ttgaagatga tccagaatgg tcttatatgc tcaatcgaca
    16081 agaatatctc ttgcagttta tgatagggta tctggtagaa ggagataagg actatattca
    16141 aaagtgcaag ttctttctat ttgattggat tgagcaggtg agagaatttt ctcctcaatc
    16201 cttgatgact agaaccttgg atacgagtat tcgttccttt acttggttga aactactctt
    16261 gctcctcttg aaatttgact tgctagagga gaaagaacta gagaaaattt tggtcagtct
    16321 agaaaagcag attgacttta tgaaaagcta ctatcgcgcc aagtacaccc ttagtaactg
    16381 ggggatttta caaacgattc cgatgcttgc tatctatcat ttcttttcag ataagatgga
    16441 cctagaagaa gcttaccatt ttgcttcaga ggagttgaaa cagcaaattg agacacagat
    16501 tttaggagat ggaagccagt ttgaacagtc gattctctat catgtagagg tttataaagc
    16561 cttgctggat ttgtgtctct tgcttccaga cttgcaagat agttaccaag agttgctgga
    16621 aaagatggcg acctatattc aaatgatgac aggcttagat ggacggactt tggcttttgg
    16681 tgatagcgat tctacagaaa cgacagaaat gttgagcctg tctgctgtgg ttttgaacca
    16741 ggaagacctt cttaacggtc tggatgttaa agtcgatttg cttagcctct tgttcctggg
    16801 gcgagaaaag gtcaagcgac tgcaggaatt tgaaaggaga gcttggcagc ctaagtccat
    16861 gatctttgaa gactctggac atgtctgcat taaggatgaa catcgttatc tatttttcaa
    16921 aaatggtccg ctaggaagtg cccatagcca tagtgacgag aatagttttt gcttacagta
    16981 tcaaggacaa cctattttca tagatgctgg gcgttattct tatcgggaga tatatgaacg
    17041 ttatctctta aagagtgctt ggagtcattc gacctgcatt gtagatggga aagctccgga
    17101 aagaatcacg ggatcctggg aatatgaata ctatcctcac tccctgtttt gtcaccataa
    17161 agaaagggag ggaatgcatt atattgaagg ggcttattgg tcagcagaac ctgatttgcc
    17221 ttatcttcac aagagaaaaa tcctcatgtt ggtagaggat gtctggctct tggtggatga
    17281 catcaggtgt caaggtcagc atgaggcgtt gactcagttt atccttgaca aggatgtgac
    17341 ctatcaagat gggaaaatca atcagttgag actatggagt gaagttgatt ttgatttgga
    17401 agataccatc atttctccta aatacaatga gcttgaaaga agtagcaaac tcaccaagcg
    17461 ccaattcttt gagaattaga tgctggatta taccatcatt gcgcatgaga gttttgaaat
    17521 catccgtcat tctgtctacc agacagatga tcgtgaagtg gaaaatgctc tggcttttga
    17581 agtgaaaaat gacgaaacag acaagctgat tctgttatta agcgaggata tttgtgtagg
    17641 tgaaaaattg tgcctcgttg acggaacaaa aatgcgtgga aaatgtctag tatatgataa
    17701 aataaatgag agaatgattc gcttgcagtg ctagaaatag gcattttgaa tagtgaatat
    17761 gttataataa gtattagtag gaggtgtttt agattggaga agaaactgac cataaaagac
    17821 attgcggaaa tggctcagac ctcgaaaaca accgtgtcat tttacctaaa cgggaaatat
    17881 gaaaaaatgt cccaagagac acgtgaaaag attgaaaaag ttattcatga aacaaattac
    17941 aaaccgagca ttgttgcgcg tagcttaaac tccaaacgaa caaaattaat cggtgttttg
    18001 attggtgata ttaccaacag tttctcaaac caaattgtta agggaattga ggatatcgcc
    18061 agccagaatg gctaccaggt aatgatagga aatagtaatt acagccaaga gagtgaggac
    18121 cggtatattg aaagcatgct tctcttggga gtagacggct ttattattca gccgacctct
    18181 aatttccgaa aatattctcg tatcatcgat gagaaaaaga agaaaatggt cttttttgat
    18241 agtcagctct atgaacaccg gactagctgg gttaaaacca ataactatga tgccgtttat
    18301 gacatgaccc agtcctgtat cgaaaaaggt tatgaacatt ttctcttgat tacagcggat
    18361 acgagtcgtt tgagtactcg gattgagcgg gcaagtggtt ttgtggatgc tttaacagat
    18421 gctaatatgc gtcacgccag tctaaccatt gaagataagc atacgaattt ggaacaaatt
    18481 aaggaatttt tacaaaaaga aatcgatccc gatgaaaaaa ctctggtatt tatccctaac
    18541 tgttgggccc tacctctagt ctttaccgtt atcaaagagt tgaattataa cttgccacaa
    18601 gttgggttga ttggttttga caatacggag tggacttgct tttcttctcc aagtgtttcg
    18661 acgctggttc agccctcctt tgaggaagga caacaggcta caaagatttt gattgatcag
    18721 attgaaggcc gcaatcaaga agaaaggcaa caagtcttgg attgtagtgt gaattggaaa
    18781 gagtcgactt tctaaaatga aggaaaatga cttgcagttt ctgttaagaa ataaaataat
    18841 cccacctaga acaagctagg tgggattatt tgcctatgaa atgagaaatt atgggagcaa
    18901 gctcctaaat caactgtttt tgatctactt ctttaactac ttgataaaag ttatagaagt
    18961 aggccaaact tgaaatgatg gttacgacta ggaatattga aaatttccat tggacagggt
    19021 tggttaaaag ttgtggaaag gatatgagga gaaagaagag ggctgcgttg aggacaggta
    19081 tccgttttga ttgtattttc tcaagtcctt tattgagcgc aggaagaaag aggagtagga
    19141 gtagtaaaac tgtatgagaa acagctcctg aaataagggc gaagaaaagg aaaatactga
    19201 taaaaacatg aatgatcagt agtctagcta gtgatttcat aaggcacctc ctaatcctgg
    19261 tcttttttag ctcttgcaat acgaagtgag tcgacaatat gtatcatcac tccgaaaaag
    19321 aaagctccca gtatagtttt aaaaatatgt tttgtattta gaagagaact gataaaattt
    19381 ggattttcac ttgttagggt atcaatgagt ggaattataa aaaatatcac tgttccataa
    19441 atcgaacctg ctttcagacc aggataacgt aattgtttct tttctttttt catagtgcac
    19501 ctcctaatcc tcatcttgat ttttcttagt ttttgcaatg cgacgggaga tgaggaactg
    19561 tatgctcgct ccgaagaaaa tagaaccgag aatgcttgat acaccatttc ttatagtgag
    19621 aagagaatga aaatagtcct gaccttcacc tatgagtatc ctgagaagag gagttataaa
    19681 aaacatccat agaccaaaga acaaacctgc tttcagacct gggtaatgta gttgcttact
    19741 ttctttctcg ctcagcatgt ctggatcaat agctgtaatc cctgtttttt tcatttggta
    19801 ggtgacatag ccagcagcga tgagggcaat cactaaaatc agaggaggat agattagagc
    19861 cacttcttga gggtatttat aggccagaag gagtggaata agatttccga aaatcatcag
    19921 ataaaagagg atgataaaga cttggttccc aatacgatcg gcctcacgcc gtttgtattc
    19981 gtcaagggga ccagaaatac cgtatgtgcg tttgatcagt ttttcagtga aggtttcttt
    20041 tttcatgagt ttgctccttt tttaaaaatc ttcctcccaa aagagactgt tgaggtcagt
    20101 ttggaggctg cgggcgagat tgagacagag ttccaaggtt ggattgtact tgtcgttttc
    20161 aatcatattg atagtctgtc tcgagacacc gatatccttg gcgagttcga gctgggaaat
    20221 acccaattcc ttgcgaaatt ctttcacacg attcatctgt tctccttttt gatttatgtc
    20281 gtatatattt gactttatta tagtctttta aacataaagt gtcaagtatt tttgacatat
    20341 tttttgaaga aatagtagtc tccttgtcct atttgtctga caagtgcaag ctggtcggat
    20401 ttgtggtaaa atagataaga tatgacaaaa gaatttcatc atgtaacggt cttactccac
    20461 gaaacgattg atatgcttga cgtaaaacct gacggtatct acgttgatgc gactttgggc
    20521 ggagcaggac atagcgagta tttattaagt aaattaagtg aaaaaggcca tctctatgcc
    20581 tttgaccagg atcagaatgc cattgacaat gcgcaaaaac gcttggcacc ttacattgag
    20641 aagggaatgg tgacctttat caaggataac ttccgtcatt tacaggcacg tttgcgcgaa
    20701 gctggtgttc aggaaattga tggaatttgt tatgacttgg gagtgtctag tcctcaattg
    20761 gaccagcgtg agcgtggttt ttcttataaa aaagatgcgc cactggacat gcggatgaat
    20821 caggatgcta gtctgacagc ctatgaagtg gttaatcatt atgactatca tgatttggct
    20881 cgtattttct tcaaatacgg tgaggataaa ttctctaaac agattgcgcg taagattgag
    20941 caagcgcgtg aagtgaagcc gattgagaca acgactgagt tagcagagat tatcaagttg
    21001 gtcaaacctg ccaaggaact caagaagaag ggtcatcctg ctaagcagat tttccaggct
    21061 attcgaattg aagtcaatga tgaactggga gcggcagatg agtccatcca acaggctatg
    21121 gatatgttgg ctctggatgg tagaatttca gtgattacct ttcattcctt agaagaccgc
    21181 ttgaccaagc aattgttcaa ggaagcttca acagttgaag ttccaaaagg cttgcctttc
    21241 atcccagatg atctcaagcc caagatggaa ttggtgtccc gtaagccaat cttgccaagt
    21301 gcggaagagt tagaagccaa taaccgctcg cactcagcca agttgcgcgt ggccagaaaa
    21361 attcacaagt aagagggaaa aagatggcag aaaaaatgga aaaaacaggt caaatactac
    21421 agatgcaact taaacggttt tcgcgtgtgg aaaaagcttt ttacttttcc attgctgtaa
    21481 ccactcttat tgtagccatt agtattattt ttatgcagac caagctcttg caagtgcaga
    21541 atgatttgac aaaaatcaat gcgcagatag aggaaaagaa gaccgaattg gacgatgcca
    21601 agcaagaggt caatgaacta ttacgtgcag aacgtttgaa agaaattgcc aattcacacg
    21661 atttgcaatt aaacaatgaa aatattagaa tagcggagta agatatgaag tggacaaaaa
    21721 gagtaatccg ttatgcgacc aaaaatcgga aatcgccggc tgaaaacaga cgcagagttg
    21781 gaaaaagtct gagtttatta tctgtctttg tttttgccat ttttttagtc aattttgcgg
    21841 tcattattgg gacaggcact cgctttggaa cagatttagc gaaggaagct aagaaggttc
    21901 atcaaaccac ccgtacagtt cctgccaaac gtgggactat ttatgaccga aatggagtcc
    21961 cgattgctga ggatgcaacc tcctataatg tctatgcggt cattgatgag aactataagt
    22021 cagcaacggg taagattctt tacgtagaaa aaacacaatt taacaaggtt gcagaggtct
    22081 ttcataagta tctggacatg gaagaatcct atgtaagaga gcaactctcg caacctaatc
    22141 tcaagcaagt ttcctttgga gcaaagggaa atgggattac ctatgccaat atgatgtcta
    22201 tcaaaaaaga attggaagct gcagaggtca aggggattga ttttacaacc agtcccaatc
    22261 gtagttaccc aaacggacaa tttgcttcta gttttatcgg tctagctcag ctccatgaaa
    22321 atgaagatgg aagcaagagc ttgctgggaa cctctggaat ggagagttcc ttgaacagta
    22381 ttcttgcagg gacagacggc attattacct atgaaaagga tcgtctgggt aatattgtac
    22441 ccggaacaga acaagtttcc caacgaacga tggacggtaa ggatgtttat acaaccattt
    22501 ccagccccct ccagtccttt atggaaaccc agatggatgc ttttcaagag aaggtaaaag
    22561 gaaagtacat gacagcgact ttggtcagtg ctaaaacagg ggaaattctg gcaacaacgc
    22621 aacgaccgac ctttgatgca gatacaaaag aaggcattac agaggacttt gtttggcgtg
    22681 atatccttta ccaaagtaac tatgagccag gttccactat gaaagtgatg atgttggctg
    22741 ctgctattga taataatacc tttccaggag gagaagtctt taatagtagt gagttaaaaa
    22801 ttgcagatgc cacgattcga gattgggacg ttaatgaagg attgactggt ggcagaacga
    22861 tgactttttc tcaaggtttt gcacactcaa gtaacgttgg gatgaccctc cttgagcaaa
    22921 agatgggaga tgctacctgg cttgattatc ttaatcgttt taaatttgga gttccgaccc
    22981 gtttcggttt gacggatgag tatgctggtc agcttcctgc ggataatatt gtcaacattg
    23041 cgcaaagctc atttggacaa gggatttcag tgacccagac gcaaatgatt cgtgccttta
    23101 cagctattgc taatgacggt gtcatgctgg agcctaaatt tattagtgcc atttatgatc
    23161 caaatgatca aactgctcgg aaatctcaaa aagaaattgt gggaaatcct gtttctaaag
    23221 atgcagctag tctaactcgg actaacatgg ttttggtagg gacggatccg gtttatggaa
    23281 ccatgtataa ccacagcaca ggcaagccaa ctgtaactgt tcctgggcaa aatgtagccc
    23341 tcaagtctgg tacggctcag attgctgacg agaaaaatgg tggttatcta gtcgggttaa
    23401 ccgactatat tttctcggct gtatcgatga gtccggctga aaatcctgat tttatcttgt
    23461 atgtgacggt ccaacaacct gaacattatt caggtattca gttgggagaa tttgccaatc
    23521 ctatcttgga gcgggcttca gctatgaaag actctctcaa tcttcaaaca acagctaagg
    23581 ctttagagca agtaagtcaa caaagtcctt atcctatgcc tagtgtcaag gatatttcac
    23641 ctggtgattt agcagaagaa ttgcgtcgca atcttgtaca acccatcgtt gtgggaacag
    23701 gaacgaagat taaaaacagt tctgctgaag aagggaagaa tcttgccccg aaccagcaag
    23761 tccttatctt atctgataaa gcagaggagg ttccagatat gtatggttgg acaaaggaga
    23821 ctgctgagac ccttgctaag tggctcaata tagaacttga atttcaaggt tcgggctcta
    23881 ctgtgcagaa gcaagatgtt cgtgctaaca cagctatcaa ggacattaaa aaaattacat
    23941 taactttagg agactaatat gtttatttcc atcagtgctg gaattgtgac atttttacta
    24001 actttagtag aaattccggc ctttatccaa ttttatagaa aggcgcaaat tacaggccag
    24061 cagatgcatg aggatgtcaa acagcatcag gcaaaagctg ggactcctac aatgggaggt
    24121 ttggttttct tgattacttc tgttttggtt gctttctttt tcgccctatt tagtagccaa
    24181 ttcagcaata atgtgggaat gattttgttc atcttggtct tgtatggctt ggtcggattt
    24241 ttagatgact ttctcaaggt ctttcgtaaa atcaatgagg ggcttaatcc taagcaaaaa
    24301 ttagctcttc agcttctagg tggagttatc ttctatcttt tctatgagcg cggtggcgat
    24361 atcctgtctg tctttggtta tccagttcat ttgggatttt tctatatttt cttcgctctt
    24421 ttctggctag tcggtttttc aaacgcagta aacttgacag acggtgttga cggtttagct
    24481 agtatttccg ttgtgattag tttgtctgcc tatggagtta ttgcctatgt gcaaggtcag
    24541 atggatattc ttctagtgat tcttgccatg attggtggtt tgctcggttt cttcatcttt
    24601 aaccataagc ctgccaaggt ctttatgggt gatgtgggaa gtttggccct aggtgggatg
    24661 ctggcagcta tctctatggc tctccaccaa gaatggactc tcttgattat cggaattgtg
    24721 tatgtttttg aaacaacttc tgttatgatg caagtcagtt atttcaaact gacaggtggt
    24781 aaacgtattt tccgtatgac gcctgtacat caccattttg agcttggggg attgtctggt
    24841 aaaggaaatc cttggagcga gtggaaggtt gacttcttct tttggggagt gggacttcta
    24901 gcaagtctcc tgaccctcgc aattttatat ttgatgtaag aatggcaccc tgatgtttca
    24961 gggtgttttt gtgtttaaat acacaatgaa aatcaaagaa caatctagaa agctaacttt
    25021 aggctgctca aaacatagta gtttgaaact agaatagtac acctctactt ctaaaatatt
    25081 gttagaaatc gatttgactg tcctgattga tttgtcctgt tcttatttcg ttttaatata
    25141 cagttttgag atggttgata gaactgacga agtcagctca aaacacggtt ttgaggttgt
    25201 agataaggag aagctgatgt ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt
    25261 cagttaaagt caaaatcctt gaccttttct gaccaatgta gtatattatg aacgtaaggt
    25321 aaatgaaagc cttactagaa cacttattta aagtaaaata gaaagaggtg ggtctatgtt
    25381 tcatctagaa attttcagaa gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga
    25441 aatagtacgt agggtagcga tctagctagt ctaaattttt taaaacaaag gtcaaagata
    25501 gtcaatatca gtaatcataa ctaagtaaac aaaaagaggt aaagaatatg aataacaact
    25561 ttaataattt taataacatg gatgatttat ttaaccaatt gatgggtggt atgcgaggat
    25621 accgttctga aaatcgccgt tacttaatta atgggcgcga agtcacacct gaggaatttg
    25681 ctcactatcg tacgactggt caattaccag gaaatgcaga aactgatgtg caaatgtcac
    25741 aacaggcatc aggtatgaaa caagacggtg tccttgcaaa actaggtcga aacttgacag
    25801 cagaagcgcg tgagggcaag ttggatcctg ttatcggacg aaacaaggaa attcaagaaa
    25861 catctgaaat cctctcacgc cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg
    25921 ttggtaagac agcagttgtc gaaggtctag cgcaagccat tgtgaacgga gatgttcctg
    25981 ctgctatcaa gaacaaggaa attatttcta ttgatatctc aggtcttgag gctggtactc
    26041 aataccgtgg tagctttgaa gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag
    26101 ggaatattat cctcttcttt gatgaaattc accaaattct tggtgctggt agcactggtg
    26161 gagacagtgg ttctaaaggg cttgcggata ttctcaagcc agctctctct cgtggagaat
    26221 tgacagtgat tggggcaaca actcaagacg aataccgtaa caccatcttg aagaatgctg
    26281 ctcttgctcg tcgtttcaac gaagtgaagg tcaatgctcc ttcagcagag aatactttta
    26341 aaattcttca aggcattcgt gacctctatc aacaacacca caatgtcatc ttgccagacg
    26401 aagtcttgaa agcagcggtg gattattctg ttcaatacat tcctcaacgt agcttgccag
    26461 ataaggctat tgaccttgtc gatgtaacgg ctgctcactt ggcggctcaa catccagtaa
    26521 cagatgtgca tgctgttgaa cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag
    26581 ttgaagcaga agattttgaa gcagctctaa actataaaac acgcattgca gaattggaaa
    26641 ggaaaatcga aaaccacaca gaagatatga aagtgactgc aagtgtcaac gatgtggctg
    26701 aatctgtgga acgaatgaca ggtatcccag tatcgcaaat gggagcttca gatatcgaac
    26761 gtttgaaaga tatggctcat cgcttgcaag acaaggtgat tggtcaagat aaggccgtag
    26821 aagctgtagc tcgtgctatc cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa
    26881 tcggcagctt cctctttgta gggtctactg gggttggtaa gacggagctt gctaagcaat
    26941 tggcactcga tatgtttgga acccaggatg cgattatccg tttggatatg tctgaataca
    27001 gtgaccgcac agctgtttct aagctaattg gtacaacagc aggctatgtg ggttatgatg
    27061 acaatagcaa taccttaaca gaacgtgttc gtcgcaatcc atactctatc attctcttgg
    27121 atgaaattga aaaggctgat cctcaagtta ttacccttct cctccaagtt ctagatgatg
    27181 gtcgtttgac agatggtcaa ggaaatacag taaacttcaa gaacactgtc attattgcga
    27241 cctcaaatgc tggatttggc tatgaagcca acttgacaga agatgcggat aaaccagaat
    27301 tgatggaccg attgaacccc ttcttccgtc cagaactcct caaccgcttt aatgcagtca
    27361 tcgagttctc acacttgact aaggaagacc tttctaagat tgtagatttg atgttggctg
    27421 aagttaacca aaccttggct aagaaagaca ttgacttggt agtcagtcaa gcggctaaag
    27481 attatatcac agaagaaggt tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg
    27541 ttgaacaaga aattcgtgat aaggtgacag acttccactt agatcattta gatgctaaac
    27601 atctggaagc agatatggaa gatggcgttt tggttattcg tgagaaagcc taagatagaa
    27661 ttttgaggat aaaaaagaag gagccagctg aaaaaaactg gttccttttg aggtacgacg
    27721 ggcatgtcgt acagtaggtt gaaactagaa tagtacacat ctacttctaa aatattgtta
    27781 gaaatcgatt tgactgtcct gattgatttg tcctgttctt atttcatttt actatatatc
    27841 tgaggtgtaa gtcctcggtg ggtacctgct accggtgctc ccaatagtga ttcccaagcc
    27901 tgactatcgt gaggtagcgg attaaaacgg tctggggata gaccgtttta agtctgacgc
    27961 tggaaataag aatcgtcaga ggaagggata gcgaaatcgt ggctctacga ataggaacgt
    28021 gataataagg cgtatatagc ggataagggg cctcaaactc taaagttcaa aaaggtagtc
    28081 gtaacctata tgcgtaaatc acgagagcaa ctgaatttgt ccattcgagg atggataaac
    28141 tatttttcat tggaaaatat gaaaagtata gtcactagca tagatgagcg cttgcgtact
    28201 cgcctacgag tgattatctg gaagcaatgg aagaagaaat ctagacgatt atggagattg
    28261 cttaagttag gggttcctaa atggatagca gataaggtat ctggctgggg tgaccactat
    28321 caattagtat ctcagaagtc ggtacttaaa cgtgctatat caaaaccagt ccttgagaaa
    28381 cgtggactgg tttcgtgttt ggattattac cttgaacgac atacgttaaa agttagttga
    28441 accgccgtat gccgaacggc acgtacggtg gtgtgagaag ggctagagat tatcccctac
    28501 tcgattttaa atcacatgac gttcaaaggc atcatctgaa atcccttgtt ccaagatgag
    28561 ttttgcccat tctttagcag agaagaggct gtggtccttg tagtttccgc aagattcgat
    28621 ggttgtccct gggacctctt cccaagtagt agtttcagcg atttccttga gcgaatcctt
    28681 gataacagct gcgattttag cactggtgtg acgtccccac ataatcatgt ggaagcctgt
    28741 gcggcaacca aatggcgaac agtcaatcat gccgtcaatg cgggtacgga tgagtttggc
    28801 taagaggtgc tcgatagtgt gaaggccggc agtagggata gagtcttcgt ttggttgcac
    28861 caagcgaata tcataattgg agatgatgtc tccttttggt cctgtttctt ccccaatcaa
    28921 gcgaacatag ggtgctttga caatggtgtg gtcaagttca aaactttcga caataacttc
    28981 ttttgacatg gtaaatcctt tcagttttct tctctcatta tatcataaag gttgctcctg
    29041 agacagagag aaaacctctc cgaggctgga gaggttgaaa tctttactta cgatataagc
    29101 ggtcgtattg gtagtatggg tcaaaggtta cgttgatacc cagtttacga aggacattct
    29161 tgtcttcatc agtcaagatg atggttgagt gggcttcgct tcctttgagg ttgccgagtt
    29221 cttccatagc gcgggtagca tcaggatttt ctgtagctgt gatagcaagt gcaatcagga
    29281 tttcatttga atgaaggcgt ggattgcggc taccgagatg atcgatttta agaccttgga
    29341 ttggcttaac aacttcaggc tcgattagtt ttacttcttt agcgatgtca gctgattttt
    29401 tgatggcgtt gatcaaggca gcggctgtag ggccaaagag ttctgagttc ttaccagtga
    29461 cgatttcccc atttggcaat tcaaaggcta gggctggtcc accagtttct tctgcttttt
    29521 ggcgcgcaac gacagcaacc ttacggtctg caggtgtgat accgaggtcg ttcatgagca
    29581 actcaatttt cttgacggca gcttcgccaa ctttttcagc tttgaagtca agaactgttt
    29641 gatagtaacg gcggatgatt tcttgtttag aagcttcgac agcggcctcg tcatctgtaa
    29701 tagcgaaacc aaccatgttg acacccatat ctgtcggtga agcgtatggt gattttccga
    29761 gaatacgttc caacatgcgt ttgagcactg ggaagatttc gatatcacgg ttgtagttga
    29821 cagtggtttc tccataggtt tggagatgga aggggtcaat catgttgaca tcatcaaggt
    29881 cagctgtggc agcttcataa gccaagttaa ctggatgatg aaggggaaga ttccaaacag
    29941 ggaaggtttc aaatttagcg tagccagatt tgatgccatt gatttggtcg tggtacatat
    30001 tggacataca cgttgccaat tttccagaac cgggtccagg agcggttacg acaatcaagt
    30061 tgcgaccggt tttgatgtag tcgtttttgc ccatgccttc tggggaaatg atgtgatcca
    30121 tatccgtagg atatcctttg attggataat gaagataaga atcaattccg tttttctcaa
    30181 gttggttgcg gaaggcatct gcagcgggtt ggccagcgta ttgtgtaatg acaacggaac
    30241 caacaaaaat ccctaattca ttgaatttgt caatcaaacg aagaacttct tggtcataag
    30301 aaatgcctaa gtcgccacgt gctttggaat gttcaatgtt gctagcatta atggcaatca
    30361 caacctcaac ctgctctttc aattcttgca agagcttgat tttgttgtca ggttcataac
    30421 caggaaggac acgagcagcg tggaaatctt ctaacatttt accgccaaac tctaagtaga
    30481 gcttgccgtc aaattggtta atgcgctcca aaatatggtc gcgttgtaaa ttcaaatact
    30541 gttcagaact aaaagcttgt tttttcattt ttttacctct ggactctatt ataataaaaa
    30601 attggaagtt aggaaactac ggagctaaaa aagaaattaa aaagattaag caaacgcttg
    30661 cacaaaattt taaaaagtgc tatcatatac tatagattat taaaataatg aggtaaacag
    30721 atgcaagaaa aatggtggca taatgccgta gtctatcaag tctatccaaa gagttttatg
    30781 gatagtaatg gagatggagt tggtgatttg ccaggtatta ccagtaagtt ggactatcta
    30841 gctaagttag gaatcacagc gatttggctt tctcccgttt atgacagccc tatggatgat
    30901 aatggctacg atattgctga ttatcaagcg attgcaacga tttttggaac catggaggat
    30961 atggatcaac tgattgcgga agctaagaag cgtgacattc gcatcatcat ggacttggtg
    31021 gttaatcata cctcagatga acatgcttgg tttgtcgaag cctgtgaaaa tactgatagc
    31081 cctgagcgag actactatat ctggcgcgat gaacccaatg acctagattc tatctttagt
    31141 gggtctgctt gggaatacga tgaaaagtca ggtcaatact atctccactt tttcagcaag
    31201 aaacagccgg atctcaactg ggaaaatgaa aaacttcgcc agaaaattta tgagatgatg
    31261 aacttctgga ttgataaagg tattggtggt ttccgtatgg atgttattga catgattggc
    31321 aaaattcctg acgagaaggt agtcaataat ggtcctatgc tccatcccta tctcaaggaa
    31381 atgaatcagg cgacctttgg agctaaggat ctcttgacag taggggagac ttggggagca
    31441 acgccagaga ttgccaagct ctactctgat ccaaaggggc aagaattgtc tatggtcttc
    31501 cagtttgaac atatcggtct tcagtatcag gaaggtcagc ctaaatggca ctatcaaaaa
    31561 gagctgaata tcgctaagtt aaaagaaatc ttcaacaaat ggcagacaga gttaggagtt
    31621 gaggacggct ggaattccct cttctggaac aaccatgacc tccctcgtat tgtctcaatc
    31681 tggggaaatg accaagaata ccgcgaaaaa tctgccaaag cctttgcaat cttacttcat
    31741 ctcatgagag gaactcctta tatctaccaa ggtgaggaga ttgggatgac caactatccg
    31801 tttgaaacac tggatcaagt agaagatatt gaatctctca actatgcgcg tgaggctctt
    31861 gaaaaaggtg ttccgattga agaaatcatg gacagtatcc gtgttattgg acgtgacaat
    31921 gcccgtaccc ctatgcaatg ggacgagagc aaaaacgctg gtttctcaac aggtcaacct
    31981 tggttggcgg ttaatccaaa ttacgagatg atcaatgtcc aagaagcgct ggcaaatcca
    32041 gattctattt tttataccta tcagaaactg gtccaaattc gcaaggagaa tagctggcta
    32101 gttcgagctg actttgaatt gcttgatacg gctgataagg tctttgctta tatacgtaag
    32161 gatggcgacc gtcgcttcct agttgtggct aacttgtcca atgaagagca agacttgaca
    32221 gtagaaggaa aagtcaaatc tgtcttgatt gaaaacactg cggctaaaga agtacttgaa
    32281 aaacaggtct tggctccatg ggatgctttc tgtgtggaaa tgactgacta gaatgagcaa
    32341 acctcaagtt tttgaagctt gaggtttttt actatagtgg attgaaacta gaatagtgca
    32401 cctctacttc taaaacattg ttagaaatcg atttgactgt cctgactaat ttgtcctatt
    32461 cttatttcat tttactatat ttgtagttga ggagaattaa gctcctcact agtaaactct
    32521 tcataatcct ttttattttt atgaagatat tgtttgaaag atgtgagttt ccacggatgg
    32581 gtttgtggag ggatatactt gcgtctttct ttttttgttc tggttcttgt tcaaagtttt
    32641 tcgaatagag ttcatgatct agtagctcct ttgtgtgata gattttgtca gcgatattga
    32701 ggtagatgtc tccgtcaaat gcttttataa ctaatgcttt cgtatttctg atgaaataga
    32761 cttcttttcc ttgttcggta gggatatagt aacgattttg gaatcggata tggtgtccac
    32821 tatcgacgac tctctccgcc agtctggcca gaatgagatt cctttcagag gggttaggaa
    32881 cctcctcgaa gacagagagt tttgtcttgt ttccaaactg ttcattaaag gtttggatgt
    32941 aggaaagcag gaaggtattg gcttcttcca aggtatgaat attgtttcgt tccagttcga
    33001 taggcaggcg agattgtagt gtctgattaa gtctttcgac tctcccttta gcttgaggga
    33061 tagaggttgt ctccagaaga atccctagtt ggtgacaggc gtatccaaat tgtgtatggg
    33121 tgtcgtcctc cattttcttc gagttggagg cttgatatag gtaaagaccg ttctcttatc
    33181 tgttttaatt tgaaggggaa cgccgtgatt gcctaaaatt tgttcgagga catgatagta
    33241 agcattcaag gtctcttgtt tatcaaaata agcgcctagg atattgccag aagcatcatc
    33301 aatggctaag tgtaagttag atgtttgggc tccaaaccat gcatgagggc tggcatccat
    33361 ttgaatgagt tctccagcaa atttctttct gggtctacta ggatgtactt ttttaggggc
    33421 ttcaaggaag ttttcagccg tcggtaagat tggattgtct aggggttgat tcaggttcag
    33481 tttagcttgt tttcttactc tcttctttgt ctttctatgg gacttaggcg acaggatatt
    33541 tttcttatag agtatttttc taacagttgt atcagagagc tgaattcctt cttcttcagc
    33601 tagcaattca cagaaatgaa ggacatttgg tttatatgtt tcataggaga ggtatttctt
    33661 taggagacgt tctttgattt catcagggat tgcatgtttt ggttttcgat ttctgtttcc
    33721 gtgtctgaag gcttcttttc ctttcagttg ataggctagt agcagacgat tgatttgtct
    33781 ttcagaaaga ttgagctcga cacaggttcg tttctttgtt ttctttcctt gcgctatagc
    33841 ttttatcaca agatattttt tagtttcatt catattcagt tggatccttt tcatatgact
    33901 attctaccaa atgggacatt ttcacgttcg atttactaaa gacattatca catt
//
LOCUS       DAVLUM010000019        33867 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLUM010000019 DAVLUM010000000
VERSION     DAVLUM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.019"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            584..1036
                     /locus_tag="VYN42_000739"
                     /pseudo
     CDS             584..1036
                     /locus_tag="VYN42_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            1055..2392
                     /locus_tag="VYN42_000740"
     CDS             1055..2392
                     /locus_tag="VYN42_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1461843.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2471..3355
                     /locus_tag="VYN42_000741"
     CDS             2471..3355
                     /locus_tag="VYN42_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1461844.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3355..4188
                     /locus_tag="VYN42_000742"
     CDS             3355..4188
                     /locus_tag="VYN42_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1461845.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4206..6299
                     /gene="nanB"
                     /locus_tag="VYN42_000743"
     CDS             4206..6299
                     /gene="nanB"
                     /locus_tag="VYN42_000743"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1461846.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPALIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGDSQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSSSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6311..7414
                     /locus_tag="VYN42_000744"
     CDS             6311..7414
                     /locus_tag="VYN42_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1461847.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7588..8286
                     /locus_tag="VYN42_000745"
     CDS             7588..8286
                     /locus_tag="VYN42_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1461848.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8305..9822
                     /locus_tag="VYN42_000746"
     CDS             8305..9822
                     /locus_tag="VYN42_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1461849.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNIADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9947..11275
                     /locus_tag="VYN42_000747"
     CDS             9947..11275
                     /locus_tag="VYN42_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1461850.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKTMKQ"
     gene            11527..12393
                     /locus_tag="VYN42_000748"
     CDS             11527..12393
                     /locus_tag="VYN42_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1461851.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12409..13248
                     /locus_tag="VYN42_000749"
     CDS             12409..13248
                     /locus_tag="VYN42_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1461852.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13521..13973
                     /locus_tag="VYN42_000750"
     CDS             13521..13973
                     /locus_tag="VYN42_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1461853.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14070..14414
                     /locus_tag="VYN42_000751"
     CDS             14070..14414
                     /locus_tag="VYN42_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461854.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVRLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            14701..15345
                     /locus_tag="VYN42_000752"
     CDS             14701..15345
                     /locus_tag="VYN42_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1461855.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15514..16431
                     /locus_tag="VYN42_000753"
     CDS             15514..16431
                     /locus_tag="VYN42_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1461856.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEVAAALIRETKERFL"
     gene            16449..17333
                     /locus_tag="VYN42_000754"
     CDS             16449..17333
                     /locus_tag="VYN42_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1461857.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17349..18200)
                     /locus_tag="VYN42_000755"
     CDS             complement(17349..18200)
                     /locus_tag="VYN42_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1461858.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18400..20457
                     /gene="pbp2b"
                     /locus_tag="VYN42_000756"
     CDS             18400..20457
                     /gene="pbp2b"
                     /locus_tag="VYN42_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1461859.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20468..21064
                     /gene="recR"
                     /locus_tag="VYN42_000757"
     CDS             20468..21064
                     /gene="recR"
                     /locus_tag="VYN42_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1461860.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21240..22283
                     /locus_tag="VYN42_000758"
     CDS             21240..22283
                     /locus_tag="VYN42_000758"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1461861.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22367..23740
                     /locus_tag="VYN42_000759"
     CDS             22367..23740
                     /locus_tag="VYN42_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1461862.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASNSLLLAP
                     ADSIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLVSQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEVK"
     gene            23835..24539
                     /locus_tag="VYN42_000760"
     CDS             23835..24539
                     /locus_tag="VYN42_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1461863.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQIVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            24758..26131
                     /gene="ftsA"
                     /locus_tag="VYN42_000761"
     CDS             24758..26131
                     /gene="ftsA"
                     /locus_tag="VYN42_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1461864.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26148..27407
                     /gene="ftsZ"
                     /locus_tag="VYN42_000762"
     CDS             26148..27407
                     /gene="ftsZ"
                     /locus_tag="VYN42_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1461865.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27412..28083
                     /locus_tag="VYN42_000763"
     CDS             27412..28083
                     /locus_tag="VYN42_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1461866.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28093..28632
                     /locus_tag="VYN42_000764"
     CDS             28093..28632
                     /locus_tag="VYN42_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1461867.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            28632..28895
                     /locus_tag="VYN42_000765"
     CDS             28632..28895
                     /locus_tag="VYN42_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1461868.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            28892..29677
                     /locus_tag="VYN42_000766"
     CDS             28892..29677
                     /locus_tag="VYN42_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1461869.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            29686..30474
                     /gene="divIVA"
                     /locus_tag="VYN42_000767"
     CDS             29686..30474
                     /gene="divIVA"
                     /locus_tag="VYN42_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1461870.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            30822..33614
                     /locus_tag="VYN42_000768"
     CDS             30822..33614
                     /locus_tag="VYN42_000768"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1461871.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10429 a         5980 c         7352 g        10106 t
ORIGIN      
        1 aagtatactc taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt
       61 tctctcttaa aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta
      121 ttagtgctag aataatagat tagaattatt ttagaaaaac gaagtgagca gcttataaat
      181 tcaagtcccc aaatagattc atactagtat cttttgcaaa aaataaaggg cgacttcctt
      241 catgaatatc aatttcatct ataaggaagg tagctaattg aactaactta tttattctgt
      301 ttgtcgctag aaaaatcaga cctccttgtg aagattgagg agatacttaa tgaaaatcaa
      361 agaagaaact agcaagctag tagcagattg cccaaaacac cgctttgagg ttgtagataa
      421 gactgaccta tataatccaa ggtgaagcga ctgtggtttg aagagatttt caaagagtat
      481 aggctagaga gtagtgtttt tatgtccttc tagtagaaaa tgctagacag aagaatgggg
      541 aacttggata ggaaaaatag attgagaaag gaggttagaa gagatgatta ttacaaaaat
      601 tagccgttta ggaacttatg tgggagtaaa tccacatttt gcaacattaa tagattttct
      661 agaaaaaaca ggactagaaa atttaacaga aggttcgatt gctatcgatg gtaatcgatt
      721 gtttgggaat tgctttactt atctagcaga tggtcaagca ggggctttct ttgaaacaca
      781 ccaaaaatat ttggatattc atttagtttt ggaaaacgaa gaagccatgg ctgttacatc
      841 gccggaaaat gtaagcgtta cccaataata tgatgaagag aaagatattg aattatacac
      901 agggaaagtg gaacagttgg ttcatttgag agctggtgaa tgcctcatca cttttccaga
      961 agatttacat caacccaagg ttcgtataaa tgatgaacct gtgaaaaaag ttgtctttaa
     1021 agttgcgatt tcttaatgta gaaagagaag aacgatgaaa aaaatgagaa agtttttatg
     1081 tctagctgga attgcgctag cggctgttgc cttggtagct tgttcaggaa aaaaagaagc
     1141 tacaactagt actgaaccac caacagaatt atctggtgaa attacaatgt ggcactcctt
     1201 tactcaagga ccccgtttag aaagtattca aaaatcagca gatgctttca tgcaaaagca
     1261 tccaaaaacg aaaatcaaga ttgaaacatt ttcttggaat gacttctata ctaaatggac
     1321 tacaggttta gcaaatggaa atgtgccaga tatcagtaca gctcttccta accaagtaat
     1381 ggaaatggtc aactcagatg ctttggttcc gctaaatgat tctatcaagc gtattggaca
     1441 agataaattt aacgaaactg ccttaaatga agcaaaaatc ggagatgatt actactctgt
     1501 tcctctttat tcacatgcac aagtcatgtg ggttagaaca gatttgttaa aagaacataa
     1561 tattgaggtt cctaaaactt gggatcaact ctatgaagct tctaaaaaat tgaaagaagc
     1621 tggagtttat ggcttgtctg ttccgtttgg aacaaatgac ttaatggcaa cacgtttctt
     1681 gaacttctac gtacgtagtg gtggaggaag cctcttaaca aaagatctta aagcagactt
     1741 gacaagccaa cttgctcaag atggtattaa atactgggtt aaattgtata aagaaatctc
     1801 acctcaagat tctttgaatt ttaatgtcct tcaacaagct accttgttct atcaaggaaa
     1861 aacagcattt gactttaact ctggcttcca tatcggagga attaatgcca acagtcctca
     1921 attgattgat tcgattgatg cttatcctat tccaaaaatc aaagagtctg ataaagacca
     1981 aggaattgaa acctcaaaca ttccaatggt tgtttggaaa aattcaaaac atccagaagt
     2041 tgctaaagca ttcttagaag cactttataa tgaagaagac tacgttaaat tccttgattc
     2101 aactccagta ggtatgttgc caactattaa ggggattagc gattctgcag cctataaaga
     2161 aaatgaaact cgtaagaagt ttaaacatgc tgaagaagta attactgaag ctgttaaaaa
     2221 aggtactgct attggttatg aaaatggacc aagtgtacaa gctggtatgt tgactaacca
     2281 acacattatt gaacaaatgt tccaagatat cattacaaat ggaacagatc ctatgaaagc
     2341 agcaaaagaa gcagaaaaac aattaaacga tttatttgag gctgttcagt agatgtaaaa
     2401 gactagaaaa taggtgggct agtgatctga aaagctctag cccaattttg taaaagaagg
     2461 gagaaggaga atggttaaag aacgtaattt aactcgctgg atatttgttt tgccagctat
     2521 gattatcgta ggattactct ttgtttatcc gtttttctcg agtatttttt atagctttac
     2581 caataagcat ttgattatgc ctaattataa atttgttggt ttggctaact ataaagctgt
     2641 gctatcagat cccaacttct ttaatgcgtt ctttaattca attaagtgga ccgttttctc
     2701 attagttggt caagttttag tagggtttgt attggcttta gctcttcaca gagtacgcca
     2761 cttcaagaaa ttatatagga ccttattgat tgttccttgg gcatttccta ccatcgttat
     2821 tgccttctct tggcagtgga ttctaaacgg ggtttatggc tacttaccta atctaatcgt
     2881 aaaattaggt ttaatggaac atacacctgc atttttgaca gatagtacat gggcattcct
     2941 atgtttggtg tttatcaaca tttggtttgg agcaccaatg attatggtta atgtgctttc
     3001 agctttgcaa acagtaccag aagaacaatt tgaggctgct aagatagatg gtgcttcaag
     3061 ttggcaggtg ttcaagttta tcgtctttcc acatattaaa gtggttgtag gacttctagt
     3121 tgttttgaga actgtatgga tctttaataa ctttgacatt atctacctca ttactggtgg
     3181 tggaccagcc aatgctacaa cgacgcttcc aatttttgct tacaacctgg gctggggaac
     3241 taaattgttg ggtcgtgctt cagcagttac agtactgctc tttatcttct tggtggcgat
     3301 ttgctttatc tactttgcta tcatcagtaa gtgggaaaag gagggtagaa aataatgaag
     3361 aagaaatcca gtatttattt agatattctc tcacatgtac ttttagttgg tgcgaccatc
     3421 gttgcagttt tcccattggt atggattatc atatcttctg tcaaagggaa aggggaatta
     3481 actcagtatc caacacgatt ttggcctgaa cagtttacat tagattattt cactcatgtt
     3541 atcaacgatt tgcacttcat tgataacatt cgaaacagtt taatcattgc cttggctaca
     3601 acccttattg cgattattat ttctgctatg gcagcctatg gtattgttcg attctttcct
     3661 aaattgggag caatcatgtc gagactactc gtcattacct acattttccc accaattttg
     3721 ttagcaattc cctattcaat tgccattgct aaagttgggt taacaaatag tttatttggc
     3781 ttgatgatgg tttatctatc ttttagtgtt ccatatgcag tttggctctt agttggattt
     3841 ttccaaacag ttccaattgg aattgaagaa gcggctagaa ttgatggtgc aaataaattt
     3901 gttacgtttt ataaagttgt gctaccgatt gtagcaccag gtattgtagc aacagctatt
     3961 tatacattta tcaatgcttg gaatgaattc ctgtatgcct tgattttgat taacaataca
     4021 ggaaagatga cagtagcagt agcccttcgt tcacttaatg gttcagaaat actagactgg
     4081 ggagatatga tggcagcgtc tgttattgta gttcttccat caattatttt cttctctatc
     4141 atccaaaata agattgcaag tggattatca gaaggatctg tgaagtagac gaaagaagga
     4201 aaaaaatgaa taaaagaggt ctttattcaa aactaggaat ttctgttgta ggcattagtc
     4261 ttttaatggg agtccccgct ttgattcatg cgaatgaatt aaactatggt caactgtcca
     4321 tatctcctat ttttcaagga ggttcatatc aactgaacaa taagagtata gatatcagcc
     4381 ctttgttatt agataaattg tctggagata gtcagacagt agtaatgaaa tttaaagcag
     4441 ataaaccaaa ctctcttcaa gctttgtttg gcctatctaa tagtaaagca ggctttaaaa
     4501 ataattactt ttcaattttc atgagagatt ctggtgagat aggtgtagaa ataagagacg
     4561 cccaaaaggg aataaattat ttattttcta gaccagcttc attatgggga aagcataaag
     4621 gacaggcagt tgaaaataca ctagtatttg tatctgattc taaagataaa acatacacaa
     4681 tgtatgttaa tggaatagaa gtgttctctg aaacagttga tacatttttg ccaatttcaa
     4741 atataaatgg tatagataag gcaacactag gagctgttaa tcgtgaaggt aaggaacatt
     4801 acctcgcaaa aggaagtatt gatgaaatca gtctatttaa caaagcaatt agtgatcagg
     4861 aagtttcaaa tattcccttg tcaaatccat ttcagttaat tttccaatca ggagattcta
     4921 ctcaagctaa ctattttaga ataccgacac tatatacatt aagtagtgga agagttctat
     4981 caagtattga tgcacgttat ggtgggactc atgattctaa aagtaagatt aatattgcca
     5041 cttcttatag tgatgataat gggaaaacgt ggagtgagcc aatttttgct atgaagttta
     5101 atgactatga ggagcagtta gtttactggc cacgagataa taaattaaag aatagtcaaa
     5161 ttagtggaag tgcttcattc atagattcat ccattgttga agataaaaaa tctgggaaaa
     5221 cgatattact agctgatgtt atgcctgcgg gtattggaaa taataatgca aataaagccg
     5281 actcaggttt taaagaaata aatggtcatt attatttaaa actaaagaag aatggagata
     5341 acgatttccg ttatacagtt agagaaaatg gtgtcgttta tgatgaaaca actaataaac
     5401 ctacaaatta tactataaat gataagtatg aagttttgga gggaggaaag tctttaacag
     5461 tcgaacaata ttcggttgat tttgatagta gctctttaag agaaaggcat aatggaaaac
     5521 aggttcctat gaatgttttc tacaaagatt cgttatttaa agtgactcct actaattata
     5581 tagcaatgac aactagtcag aatagaggag agagttggga acaatttaag ttgttgcctc
     5641 cgttcttagg agaaaaacat aatggaactt acttgtgtcc tggacaaggt ttagcattaa
     5701 aatcaagtaa cagattgatt tttgcaacat atactagtgg agaactaacc tatctcattt
     5761 ctgatgatag tggtcaaaca tggaagaaat cctcagcttc aattccgttt aaaaatgcaa
     5821 cagcagaagc acaaatggtt gaactgagag atggtgtgat tagaacattc tttagaacca
     5881 ctacaggtaa gatagcttat atgactagta gagattctgg agaaacatgg tcggaagttt
     5941 cgtatattga tggaatccaa caaacttcat atggcacaca agtatctgca attaaatact
     6001 ctcaattaat tgatggaaaa gaagcagtca ttttgagtac accaaattct agaagtggcc
     6061 gtaagggagg tcaattagtt gtcggtttag tcaataaaga agatgatagt attgattgga
     6121 aataccacta tgatattgat ttgccttcgt atggttatgc ctattctgcg attacagaat
     6181 tgccaaatca tcacataggt gtactgtttg aaaaatatga ttcgtggtcg agaaatgaat
     6241 tgcatttaag caatgtagtt cagtatatag atttggaaat taatgattta acaaaataaa
     6301 ggagaaaaac atggttaaat acggtgttgt tggagcaggg tattttggag ctgaattggc
     6361 tcgctacatg caaaagaatg atggagcaga gattactctt ctctatgatc cagataatgc
     6421 agaggcgatt gcagaagaat tgggggcaaa agtagcaagt tccttagatg agttggtttc
     6481 tagcgatgaa gtagattgtg ttatcgtcgc aactccaaat aatcttcata aggaaccggt
     6541 tattaaggct gcacagcatg gtaaaaatgt tttctgtgaa aaaccaattg cgctttctta
     6601 tcaagattgt cgcgagatgg tagatgcgtg taaagaaaac aatgtaacct ttatggcagg
     6661 acatattatg aatttcttta atggtgttca tcatgcaaaa gaactcatta atcaaggagt
     6721 tatcggagac gttctatatt gtcatacagc tcgtaatggt tgggaagaac aacaaccgtc
     6781 agtatcatgg aaaaaaattc gtgaaaaatc aggtggtcac ttgtatcacc acatccatga
     6841 attggattgc gttcaattcc ttatgggggg catgcctgaa actgtaacca tgacaggtgg
     6901 aaatgtggcc catgaaggtg aacatttcgg tgatgaagat gatatgattt ttgtcaatat
     6961 ggaattttct aataagcgtt ttgccttgtt agaatggggt tcagcttatc gttggggtga
     7021 acattatgtc ttaatccaag gaagcaaagg tgccatccgc ttagacttat tcaactgtaa
     7081 aggaactctt aagctagatg ggcaagaaag ctatttcttg attcacgaat cgcaagaaga
     7141 agatgatgat cggactcgta tctatcatag tacagagatg gatggagcaa ttgcttatgg
     7201 taaaccaggt aaacgtactc cattatggct atcatctgtc attgataaag aaatgcgcta
     7261 tctgcatgag attatggaag gagctccagt atcagaagaa tttgcaaaac ttttgacagg
     7321 tgaagctgcc ctagaagcaa ttgctactgc agatgcttgt acccagtcta tgtttgaaga
     7381 tcgcaaagta aaattgtcag aaattgtaaa ataaattttg gtattctcct atttataggt
     7441 cgacttgctc ctctgaaagt acttttagag gagctgtttg actttgctag tttttgaaac
     7501 tgaaatctat tatactacaa actattgaaa gcgttttaat tttaaggtat aataatctca
     7561 tagaaataaa gaaaaggagg aaagaggatg ccacagatta gcaaagaagc cttgattgag
     7621 caaatcaaag atggaatcat cgtttcttgt caggctcttc ctcatgaacc gctttataca
     7681 gaagcgggag gggtgattcc cttgctggtc aaagcggctg agcaaggtgg agcagtcggt
     7741 atccgagcaa acagtgttcg cgatatcaag gaaattaagg aagtcactaa acttccaatc
     7801 attgggatta tcaaacgtga ttatccacct caggaaccct tcatcacggc tactatgaaa
     7861 gaagttgatg aattggcaga actggacatc gaggtgattg ctctggattg taccaagcgt
     7921 gaacgctacg atggtttgga aattcaagag ttcattcgtc aggttaagga gaaatatcct
     7981 aatcagcttt tgatggctga tactagtatc ttcgaagaag ggctagcagc tgtagaagca
     8041 ggaattgact ttgtcggaac aaccttatca ggctacacat cctacagtcc aaaagtagac
     8101 ggtccagatt ttgaattgat taagaaactc tgtgatgccg gtgtagatgt cattgcagaa
     8161 ggaaaaattc atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc
     8221 gttgttggtg gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt
     8281 aaataagatg tgagggggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt
     8341 atgttaccta tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt
     8401 tcaaacccaa ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata
     8461 ttccaagtaa tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt
     8521 gtgggattat gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta
     8581 actggttact tagttatgac tgcaacgatc aaagctttag taaaactttt tatggcagaa
     8641 ggatctgcaa ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat
     8701 ttgcacaacc gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca
     8761 cgcttcgttc ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt
     8821 atttggccac ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt
     8881 ccaattggaa cttttctata tggattttta atgagacttt ctggagcagt aggcttacat
     8941 catataattt accctatgtt ttggtatact gaacttggtg gtgttgaaac tgttgcagga
     9001 caaacagtgg ttggagctca aaaaatattt tttgctcaat tagccgattt ggcccattct
     9061 ggattattta cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt
     9121 ttaccggctg cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac
     9181 gcgggtttgt tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt
     9241 gaatttatgt ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt
     9301 gttagcttct ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt
     9361 gtaatcgatt tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt
     9421 cagattccat ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt
     9481 actcaattca acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct
     9541 gaatccgcag attcaacttc aaatattgca gattatttaa aacaggatag cctacaaatt
     9601 atcagagcct tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta
     9661 cgtgtagctg taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca
     9721 gttgatgtct tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta
     9781 tataaaaata gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata
     9841 aaaaacagag gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag
     9901 aactcattat ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa
     9961 attagcttgt acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc
    10021 tggcggaagt aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg
    10081 gtgggcattc ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa
    10141 atcaatcatc gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat
    10201 cgacttcaag tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga
    10261 cgtactcttt gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga
    10321 gttgaacgac ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca
    10381 agcaagtaaa gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat
    10441 ggcaatgaac aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg
    10501 gacaactgat gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg
    10561 ttcattgttc agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct
    10621 ttatagcggt tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt
    10681 cgtcaaaggt cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc
    10741 acaatttgac ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat
    10801 cctttgggca ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga
    10861 agtggtagaa gtaccattcc catcagacga aggtaagcca gctcttgagt accttgtaaa
    10921 cgggtttgca gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat
    10981 ccagtttatc gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt
    11041 cccagtccgt acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg
    11101 ctggactcaa tactactcac catactacaa cactattgat ggatttgctg aaatgagaac
    11161 actttggttc ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cagatgcttt
    11221 gaaagccttc actgaaaaag cgaacgaaac aatcaaaaaa actatgaaac aatagtcctt
    11281 agttattcta taaaaagtag ttttttaaag aacctaagag tgtatacccc cttttccctc
    11341 tacacagata gtgtaagaaa agggggcttt tgtttaaaat gtaagaaact gtcacgaaat
    11401 taaaatgaag ttcttacata agcgaaccat aaaaaatttc attttgattt taaaacagtt
    11461 caagaaagtc aaaaaattat tctatttgaa agagaggtgc cgactgtgaa agtcaataaa
    11521 atccgtatgc gggaaacagt gatttcctac gctttcctag caccagtatt attcttcttt
    11581 gtcatctttg tgttggctcc gatggtgatg ggcttcatta caagtttctt taactactca
    11641 atgactaaat ttgagtttgt gggcttagat aactatatcc gtatgtttaa agatcctgtc
    11701 tttacaaaat ctctgattaa cacagttatt ttggttattg gatctgtacc agttgttgtt
    11761 ctattctcac tctttgtagc atctcagacc tatcatcaaa atgtcattgc cagatccttc
    11821 taccgtttcg tcttcttcct tcctgttgta acgggtagtg ttgccgtgac agttgtttgg
    11881 aaatggattt atgacccgct atcagggatt ctaaactttg tccttaagtc aagccacatc
    11941 atcagccaaa acatttcttg gttgggagat aaaaactggg cattgatggc gattatgatt
    12001 attctcttga ccacttcagt tggtcagccc atcatccttt atatcgctgc catggggaat
    12061 attgacaatt cactggttga agcggcgcgt gttgatggcg caactgagtt tcaagttttt
    12121 tggaagatta aatggccaag ccttcttcca acaactcttt atattgcaat catcacaaca
    12181 attaactcat tccagtgttt cgccttgatt cagcttttga catctggtgg tccaaactac
    12241 tcaacaagta ccttgatgta ctacctttac gaaaaagcct tccaattgac agaatacggc
    12301 tatgccaaca caattggtgt cttcttggca gtcatgattg ctatcgtaag ctttgttcaa
    12361 tttaaagtac ttggaaacga cgtagaatac taaagaaagg agacagctat gcaatctaca
    12421 gaaaaaaaac cattaacagc ctttactgtt atttcaacaa tcattttgct cttgttgact
    12481 gtgctgttca tctttccatt ctactggatt ttgacagggg cattcaaatc acaacctgat
    12541 acaattgtta ttcctcctca gtggttccct aaaatgccaa ccatggaaaa cttccaacaa
    12601 ctcatggtgc agaaccctgc cttgcaatgg atgtggaact cagtatttat ctcattggta
    12661 accatgttct tagtttgtgc aacctcatct ctagcaggtt atgtattggc taaaaaacgt
    12721 ttctatggtc aacgcattct atttgctatc tttatcgctg ctatggcgct tccaaaacaa
    12781 gttgtccttg taccattggt acgtatcgtc aacttcatgg gaatccacga tactctctgg
    12841 gcagttatct tgcctttgat tggatggcca ttcggtgtct tcctcatgaa acaatttagt
    12901 gaaaatattc ctacagagtt gcttgaatca gctaaaatcg acggttgtgg tgagattcgt
    12961 accttctgga gtgtagcctt cccgattgtg aaaccagggt ttgcagccct tgcaatcttt
    13021 accttcatca atacttggaa tgactacttc atgcaattgg taatgttgac ttcacgtaac
    13081 aatttgacca tctcacttgg ggttgcgacc atgcaggctg aaatggcaac caactatggt
    13141 ttgattatgg caggagctgc ccttgctgct gttccaatcg tcacagtctt ccttgtcttc
    13201 caaaaatcct tcacacaggg tattactatg ggagcggtca aaggataata ctctgcgaaa
    13261 atcgaatgca aactacgtca gcttcacctt gccatactta agtattgcct gcggttagct
    13321 tcctagtttg ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa
    13381 gtatatttta tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg
    13441 cagttacttt atgaagtttt gtcagacact tatcaactta agaatggttt tagttaacta
    13501 tcagaaacga aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag
    13561 ggattcatcc caatttagac aaggctatcg actacctcta ccaacatcgt aaagattcat
    13621 tcgaattagg aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg
    13681 tcctcaatca agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt
    13741 tgctgataga agggcatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag
    13801 cattcgacga agcgagtgac attggctttg ttcattgtca tgaacactac ccgctcttgt
    13861 tgggttatca caattttgcg attttcttcc caggtgagcc acatcagcca aatggttatg
    13921 caggcatgga agaaaaggtt cgaaaatatc tctttaaaat cttgattgat taaaaatagg
    13981 atgaattgtt tttttgtaaa gctttgataa tactctacca tgaaattgat ctttgtgagg
    14041 tagagaaatg agaataaaat atttaaaaat tggtatcttc taagtatgct gcaagagcta
    14101 gtttcttaga tggacagggg attacagttg atgagatgtc ctggataatt aggggcattg
    14161 tgaatggatt gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta
    14221 gtatggcgcg ctcgatctta agtagggcag ctgcaactgc ggcagcaaga gtaagattat
    14281 tgactaagat ttttggatgg attttacgaa tagctgtgct cgcagctgat gtatatggta
    14341 attttgccaa caatattgct gcagcttggg atgcacatga taaaatccct aacaatggtc
    14401 gtataaactt ttaaaatgcg agaatgaaag cactttgtat ttttttattg tatatgttag
    14461 cttggacagt gcttgcaatg ataatccgtg gagggctaga tggatttgat gaacacactt
    14521 ggcgtaatat tttagctagt gcgttgtcct cgctatacat acattatata tccatagata
    14581 gaaaaagaaa aaagtccaaa agaaaaaaga aaaaatagat ttgttcatgg tagggactta
    14641 tgaaagcttt actaacaaaa aagaaaacag tttacaaaga aaaatgatgg aggagtaaac
    14701 atggcacaaa aaggagtaag ccttatcaag gcagcatttg atacagataa ctttcttatg
    14761 cgttttagtg agaaagtctt ggacatcgtg acagccaatc ttctttttgt cgtctcttgt
    14821 ttgcccatcg tgacgattgg agtggctaaa atcagcctct acgagaccat gtttgagatt
    14881 aagaagagca gacgggtgcc tgtttttaaa atctatctaa gatctttcaa gcaaaatctg
    14941 aaactaggtc ttcagttagg tctgcttgag ttgggcattg tttcattaag cctcctagat
    15001 ctttatctct tttggggtca aacagctctg ccctttcaat tgctgaaagc tatttgtcta
    15061 ggcattctga ttttccttac gattgtgatg ttggctagct atccaatcgc ggcacgttat
    15121 gatttaactt ggaaagaagt gttacaaaaa gggcttatct tggcaagttt taactttcct
    15181 tggttcttcc tcatgttagc cattcttgtc ctcattgtga tggttcttta tctgtccgcc
    15241 ttcagtctac tcttaggtgg ctcagtcttc ctactttttg ggtttggact attggtcttt
    15301 atccagactg gattgatgga gaaaattttc gcaaaatacc aataggagcc ttatttctga
    15361 aactactttc aaaggctcca aacgctattc tataagcgag aaactaaaat ctaagtgtct
    15421 ataagatatt gaaagccttt tcggtaaagt gtatactaaa gaagtaaaga aaaatctgct
    15481 ttagcagaaa ataaaaataa taggagaaaa tctatgtcag atttgaaaaa atacgaaggt
    15541 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
    15601 cgtgccttgg ttcaatactt cattgataaa ggtgttcaag gtctttatgt caatggttct
    15661 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
    15721 gcggtagcca aaggtaaatt gaccatcatt gctcatgttg cctgcaacaa tactaaagac
    15781 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
    15841 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
    15901 gcagctccaa acacagacta cgtgatttac aacattcctc aattggcagg ggttgctttg
    15961 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
    16021 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gcggggaaga ccatattgtc
    16081 tttaacggtc cagatgaaca gttcctaggt ggccgcctca tgggggctag ggctggtatc
    16141 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    16201 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    16261 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    16321 ttgaatattg gttctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    16381 gtagaagtag ctgcagcctt gattcgtgaa accaaggagc gcttcctcta atctaaaagg
    16441 aggtatttat gacatactac gttgcaattg atatcggtgg aaccaacatc aagtatggtt
    16501 tggttgatca agaggggcaa cttcttgaat cgcatgaaat gccaactgag gcgcataagg
    16561 gtggacctca tatcttacaa aagaccaaag atatcgtagc tagttattta gaaaaaggcc
    16621 cagtagcagg tgttgccata tcttctgctg ggatggtgga tccggataag ggtgagattt
    16681 tctatgctgg gccgcaaatc cctaactacg caggcaccca gttcaaaaag gaaatcgaag
    16741 aaagctttac tattccttgt gagattgaaa atgatgtcaa ctgtgcaggt cttgctgagg
    16801 cagtatctgg ttcaggcaag ggagcaagtg tgacactttg cttgaccatt ggaacaggta
    16861 tcggtggttg cttgattatg gataggaaag tcttccatgg ttttagcaat tcagcctgtg
    16921 aagtcgggta tatgcatatg caggatggag cttttcagga tctcgcttct acaacagctt
    16981 tagtgaaata tgtagctgaa gcccatggag aagatgttga tcagtggaat ggccgacgta
    17041 tctttaagga agctactgaa ggaaacaaaa tctgcatgga aggcattgac cgtatggttg
    17101 actatctagg aaaaggtctg gcaaatattt gctacgttgc caatccagaa gtggttattc
    17161 ttggtggtgg tatcatgggg caagaggcta tcctcaaacc taagatccgc acagccttga
    17221 aagaggcttt ggtaccaagt ttagcagaaa aaacacgatt agaatttgcc catcaccaaa
    17281 atacagcagg gatgttgggt gcatattatc attttaagac aaaacaatcc tagtttggct
    17341 cagccaaact aggattttct tacacgtttt tgtctacgat agccgttgag ttttttattt
    17401 tcccagtagc tattaaagat tttttccttg ctttcgcgat tgatttccaa aaagtaggca
    17461 taaatcaaat cgataaagaa gagcatagga agttgagcgg atattcgttg gatataggag
    17521 ggttggctgt gggtggctac aagaacagtc tctgtatagg tctggctatc tttattggga
    17581 acacttgtaa agagtacagt ctttgccccc atctccttag catctaatag actatctaaa
    17641 atagaaggag ttgagcctga aagtgagaag cccagtacta gacaattttc atccatgatg
    17701 ctggttgtcc aggcaaagcc gtcttggtct gtcaaagctt cgcagaccac acctagtcgc
    17761 ataaaacgta atttcatttc acgggcgacg aggccagaac tccctgttcc aaagaagtag
    17821 atacgctcag catcttcgat tagctgggca attcgttcta gttggatttc gtcaatcaag
    17881 tcttgtgttt gttccctcat attgctataa cttctgagga ctcgtttggt cagtggactg
    17941 tgcttggaga cttggttggc ttgattttct gcctgatgtt ggtattggaa aataaattct
    18001 cggtagccag taaagccaca ctttttagca aagcgggtca aagcagcttg agaaatatgt
    18061 aatttttggg tgacttgttg agaagataaa tcatctgtaa tcgtttcagc ttgcaaaaaa
    18121 tagcgagcga tttcttgttc taggtctgtc atttcttcaa aatgtgaatc aatgatagtt
    18181 gcgatatctg gtttgtccat agggaaagct cctttacatg agtcatactg gaagactaga
    18241 tcagagaata gtcacacttc attataacac ataatataag gatagataaa taaaaacgca
    18301 tctctgtttt aaaaacgaaa aaatcgaaaa agcttctctc ttttccataa ttttctactc
    18361 aaattgtggt acaattaaga gtaagatttt aagttagaaa tgagactgat ttgtatgaga
    18421 aaatttaaca gccattcgat tccgattcgg cttaatttat tgttttcaat cgtcatttta
    18481 ctctttatga ccattattgg tcgtttgttg tatatgcagg ttttgaacaa ggatttttac
    18541 gaaaaaaagc tagcttcagc tagtcagacc aagattacaa gcagttcagc ccgtggggaa
    18601 atttatgatg ctagtggaaa acctttggta gaaaatacgt taaagcaggt tgtttccttt
    18661 acgcgtagca ataaaatgac ggctacagac ttaaaagaaa cagctaaaaa gttactgact
    18721 tatgtgagca tcagttctcc aaatttgaca gaacgccagc tggcggatta ctatttggct
    18781 gatcctgaaa tctataaaaa aatagtggaa gctctcccaa gtgagaaacg cttggattca
    18841 gatggcaatc gtctatccga atcagaactg tataacaatg cggtcgatag tgtacaaacg
    18901 agtcaactaa actatacaga ggatgaaaag aaagaaatct atctttttag tcagttaaat
    18961 gctgttggaa actttgcgac aggaaccatt gcgacagatc ctctaaatga ttctcaggtg
    19021 gctgttattg cctctatttc aaaggagatg cctggcatta gtatttctac ttcttgggat
    19081 agaaaggttt tggaaacttc cctttcttct atagttggga gtgtatccag tgaaaaagct
    19141 ggtctcccag cggaagaagc agaagcctat cttaaaaaag gctattctct aaatgatcgt
    19201 gtaggaacct cctatttgga aaagcaatat gaagagacct tacaaggaaa acgctcggta
    19261 aaagaaatcc atctggataa atatggcaat atggaaagcg tggatacaat tgaggaaggt
    19321 agtaagggaa acaatatcaa actgaccatt gatttggcct tccaagatag cgtggatgct
    19381 ttactgaaaa gttatttcaa ttccgagcta gaaaatggtg gagccaagta ttctgaaggt
    19441 gtctatgcag tcgcccttaa cccaaaaaca ggtgcggttt tgtctatgtc agggattaaa
    19501 catgacttga aaacgggaga gttgacgcct gattccttgg gaacggtaac caatgtcttt
    19561 gttccaggtt cggttgtcaa ggcggcgacc atcagctcag gttgggaaaa tggagtcttg
    19621 tcaggaaacc agaccttgac agaccagtcc attgtcttcc aaggttcagc tcccatcaat
    19681 tcttggtata ctcaggctta cggttcattc cctatcacag cggtccaagc tctggagtat
    19741 tcatcaaata cctatatggt ccaaacagcc ttaggtctta tggggcaaac ctatcaaccc
    19801 aatatgtttg tcggcaccag caatctagag tctgctatgg agaaactgcg ttcaaccttt
    19861 ggcgaatatg gcttgggtac tgcgacagga attgacctac cagatgaatc tactggattt
    19921 gttcccaaag agtatagctt tgctaattac attactaatg cctttgggca gtttgataac
    19981 tatacgccga tgcagttggc tcagtatgta gcaactattg caaataatgg tgttcgtgtg
    20041 gctcctcgta ttgttgaagg catttatggt aataatgata agggaggact gggtgacttg
    20101 attcagcaac tgcaaccgac agagatgaat aaggtcaata tatccgactc cgatatgagc
    20161 atcttgcacc aaggttttta tcaggttgcc catggtacta gtggattgac aactggacgt
    20221 gccttttcaa atggtgcctt ggtatccatt agcggaaaaa caggtacagc cgaaagctat
    20281 gtggcagatg gtcagcaagc aaccaatacc aatgcggtgg cctatgcccc atctgataat
    20341 ccccaaatcg ctgtcgcagt ggtctttcct cataatacca atctaacaaa tggtgtagga
    20401 ccttccattg cgcgtgacat tatcaatctg tatcaaaaat accatccaat gaactagaaa
    20461 ggaaattatg ctttatccaa cacctattgc caagttgatt gacagttatt ctaagttacc
    20521 aggtatcggg attaagacgg ctacgcgtct ggccttttat acgattggga tgtctgctga
    20581 tgatgtcaat gaatttgcaa aaaatctcct ttctgctaag agagaattga catattgttc
    20641 tatttgtgga cgtttgacag acgacgatcc ttgttctatc tgtactgatc cgactcgtga
    20701 ccagacaaca attttagttc ttgaggatag tagagatgtg gcagccatgg aaaatatcca
    20761 agaataccat ggactctatc atgtcctgca tggcctcatt tctcctatga atggtatcag
    20821 tccggacgat atcaatctca agagccttat gactcgtctt atggatagtg aggtttcaga
    20881 agtgattgtg gcgactaatg ctacagcgga tggtgaagcg acttccatgt atctttcacg
    20941 tttgctcaag ccggctggta tcaaggttac gcgtctagca cgaggtctcg ctgtgggagc
    21001 ggacattgag tatgcggacg aagtgacact cttacgagcg attgaaaatc ggacagagtt
    21061 gtaagtgtag gcaaatttac gaactccctt catttataaa aaatcaaaga ggctgaaaat
    21121 cgttcctatc ggcctctttt tgtatagtgt gatgagtagg atcgggttca agttttaaaa
    21181 aaccaagcaa atatgatata ctaaagagcg agtattctag tagaattagg acaaataata
    21241 tgaaacaaac gattattctt ttatatggtg gacggagtgc ggaacgcgaa gtctctgtcc
    21301 tttcagctga gagtgtcatg cgtgcggtca attacgaccg tttcacagtc aagactttct
    21361 ttatcagtca gtcaggtgac tttatcaaaa cacaggaatt tagtcatgct ccgggtcaag
    21421 aagaccgtct catgaccaat gaaaccattg attgggataa gaaagttgca ccaagtgcta
    21481 tctacgaaga aggtgcagtg gtctttccag tccttcacgg gccaatggga gaagatggct
    21541 ctgttcaagg attcttggaa gttttgaaaa tgccttacgt tggttgcaac attttgtcat
    21601 caagtcttgc catggataaa atcacgacta agcgtgttct ggaatctgct ggtattgccc
    21661 aagttcctta tgtggctatc gttgaaggcg atgatgtgac tgctaaaatc gctgaagtgg
    21721 aagaaaaatt ggcttatcca gtcttcacta agccgtcaaa catggggtct agtgtcggta
    21781 tttctaagtc tgaaaaccaa gaagaactcc gtcaagcctt aaaacttgcc ttccgatatg
    21841 acagccgtgt cttggttgag caaggagtga atgcccgtga aattgaggtt ggcctcttgg
    21901 gtaactacga tgtcaagagc acgctacctg gagaagttgt caaggacgtt gccttttatg
    21961 attacgatgc caagtatatt gataacaaga ttactatgga tattcctgcc aaaatcagtg
    22021 atgatgtggt ggctgtcatg cgtcaaaatg cagaaacagc cttccgtgcc attggtggcc
    22081 ttggtctatc tcgttgcgat ttcttctata cagataaggg agagattttt ctcaacgagc
    22141 tcaataccat gccaggtttc acccagtggt ctatgtaccc actactttgg gacaatatgg
    22201 ggatcagcta cccagaacta atcgagcgtt tggttgacct tgccaaggaa agttttgaca
    22261 agcgcgaagc gcatttgata taaaattaaa gagagggtag aagccagaac catcactgca
    22321 aggtgactag agttctcgga cttcagccct ttttaaagga gtagaaatga aattaacaat
    22381 ccatgaaatt gcccaagttg ttggagccaa aaatgatatc agtatctttg aggacaccca
    22441 gttagaaaaa gctgagtttg atagtcgttt gattggaact ggagatttat ttgtgccact
    22501 taaaggtgcg cgtgacggtc atgactttat cgaaagagct tttgaaaatg gtgcggcagc
    22561 aaccctgtct gagaaagagg ttgcaaatca tccctacatt ctagtagatg atgttttgac
    22621 tgcctttcaa caactagctg cctactatct tgaaaaaaca gctgttgatg tctttgcggt
    22681 tacgggttca aatggcaaga caacgaccaa ggatatgtta gcgcatttac tatcaacaac
    22741 ctacaagacc tacaaaacac aaggaaacta caataacgag attggtcttc catacacagt
    22801 tctccatatg cctgaaggga cagaaaagtt ggtcttggag atggggcagg accacttggg
    22861 cgatattcat ctcttgtctg aattggctcg tccaaaaaca gccatcgtga ccttggttgg
    22921 agaagcccat ttggcctttt tcaaagatcg ttcggaaatc gctaaaggga aaatgcaaat
    22981 tgcagatggc atggcttcga attccttgct cttggcgcca gcagattcga ttgtagagga
    23041 ctacttgcca actgataaaa aggtggtccg ttttgggcaa ggggcagagt tggaaatcac
    23101 agacttggtt gagcgtaagg acagtctgac ctttaaggct aatttcttgg aacaagccct
    23161 tgatttgcca gtgactggta agtacaatgc taccaatgct atgattgcat cctatgttgc
    23221 cctacaagaa ggagtttcag aggagcaaat tcatcaggcc ttccaaggtc ttgaattgac
    23281 gcgtaatcgt actgagtgga agaaagcagc caatggagca gatatcctgt cagacgtata
    23341 taatgccaat ccaactgcta tgaagctgat tttagagact ttctctgcca ttccagccaa
    23401 tgaaggtggc aagaaaattg cagtgttggc ggatatgaag gagcttggtg accagtctat
    23461 tcaactccat aaccagatga ttttgagcct ttctccagat gtgcttgata ccgttatttt
    23521 ctatggagaa gacattgctg aattagccca attggtcagt caaatgttcc caattggcca
    23581 cgtttactac ttcaagaaaa cagaagacca ggatcaattt gaagacctag tcaagcaggt
    23641 taaggaaagc cttggagcct atgaccaaat cttgctaaaa ggttctaact ctatgaatct
    23701 agccaaattg gtagaacgtt tagaaaatga agtcaagtga ttttgtcaaa catttacgta
    23761 tttctaaatc catttttaac aactagcatg gtataataaa atgcaggaaa attttgaatc
    23821 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    23881 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    23941 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagattg
    24001 ttcagttaat ccttctttat ggttggtact gggtcaatca tatgccactg tcagaaagcc
    24061 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    24121 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    24181 cagtgccaga tgcttaccct tttccacata tcaccattct atcctttatc tttggtcatt
    24241 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    24301 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    24361 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    24421 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    24481 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    24541 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    24601 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    24661 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    24721 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    24781 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    24841 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    24901 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    24961 aggcatttcg attaaatcag taaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    25021 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    25081 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    25141 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    25201 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    25261 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    25321 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    25381 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    25441 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    25501 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    25561 caaagaaacc ttccaagtag aggttattgg agaagtggaa gcagtcgaag tgacggaagc
    25621 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    25681 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    25741 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    25801 tgttccaaat caagttggta tccgtaatcc agcttttgcg catgtgatta gtttatcaga
    25861 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    25921 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    25981 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagtcggtgg cgcctacaga
    26041 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    26101 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    26161 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    26221 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    26281 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    26341 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    26401 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    26461 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    26521 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    26581 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    26641 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    26701 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    26761 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    26821 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    26881 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    26941 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    27001 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    27061 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    27121 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    27181 atggctttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    27241 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    27301 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    27361 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    27421 aaagaaaata cagaacttgt ttttcgagaa gttgcagagg ctagtctgag tgctaatcga
    27481 gagagtggtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    27541 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    27601 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    27661 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    27721 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    27781 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    27841 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    27901 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    27961 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    28021 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    28081 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    28141 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    28201 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggctgg tacaaaagag
    28261 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    28321 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    28381 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    28441 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    28501 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    28561 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    28621 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    28681 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    28741 gtcgttggat tgtagcgttg gtgaaaccag tgcttgctcc cttgcaacgc ctgcctttac
    28801 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    28861 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    28921 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    28981 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    29041 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    29101 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    29161 ccaggaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    29221 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    29281 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    29341 aattggtcgt atacctgttt cgctggagga acgtcctttc accgagaaaa tagataagct
    29401 agaacagtat cgagaactgg atttatctgt gtctagtttt cgattagatg ttcttttatc
    29461 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    29521 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    29581 tgtgagaaaa tttggtcgct tgagattact tcaagataag ggacaaacga aaaaagagaa
    29641 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    29701 ttagaaataa aggacaagac ttttggaact cgattcagag gttttgatcc agaagaagtc
    29761 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    29821 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    29881 tcattgagcc agtctgtatt gattgctcag gatacagctg agagagtgaa acaggcggcg
    29941 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    30001 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    30061 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    30121 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    30181 acagctactt atcttcaaac cagtgatgaa gcctttaaag aagtggttag cgaagtactt
    30241 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    30301 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    30361 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    30421 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    30481 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcaccg ggatttgaag
    30541 caccgcaaga atctgttaca attttataag aaatattctg agaacaatat cttatcctta
    30601 tattcccagc gagcaggaga tggtgtgagt cctgcattcc ctatcgataa gattatcctc
    30661 tcaaaaactc aagtctgaat ctagtaagat ttgacgttcc ccacgttacg ggataagagg
    30721 gagaaagact aaaacttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    30781 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagacaccc
    30841 ttaatcttgg gaaaactgaa ttcccaatgc gtgcaggcct tcctaccaaa gagccagttt
    30901 ggcaaaagga atgggaagat gcaaaacttt atcaacgtcg tcaagaattg aaccaaggaa
    30961 aacctcattt caccttgcat gatggccctc catacgctaa cggaaatatc cacgttggac
    31021 atgctatgaa caagatttca aaagatatca ttgttcgttc taagtctatg tcaggatttt
    31081 acgcaccatt tattcctggt tgggatactc atggtctgcc aatcgagcaa gtattgtcaa
    31141 aacaaggtgt caaacgtaaa gaaatggact tggttgagta cttgaaactt tgccgtgagt
    31201 acgctctttc tcaagtagat aaacaacgtg aagattttaa acgtttgggt gtttctggtg
    31261 actgggaaaa tccatatgtg accttgactc ctgactatga agcagctcaa attcgtgtat
    31321 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    31381 ggtcatctga gtcagccctt gctgaagcag agattgaata ccatgatttg gtttcaactt
    31441 ccctttacta tgccaacaag gtaaaagatg gcaaaggagt tctagataca gatacttata
    31501 tcgttgtctg gacaacgact ccatttacca tcacagcttc tcgtggtttg acggttggtg
    31561 cagatattga ttacgttttg gttcaacctg ctggtgaagc tcgtaagttt gtcgttgctg
    31621 ctgaattatt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gttttggaaa
    31681 cttaccgtgg ccaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    31741 aagagttggt aattcttggt gaccacgtta cgactgactc tggtacaggt attgttcata
    31801 cagcccctgg ttttggtgag gacgattaca atgttggtat tgctaataat cttgaagtcg
    31861 cagtgactgt tgatgaacgt ggtatcatga tgaagaatgc tggtcctgaa tttgaaggtc
    31921 aattctatga aaaggtagtt ccaactgtta ttgaaaaact tggtaacctc cttcttgccc
    31981 aagaagaaat ctctcactca tatccatttg actggcgtac taagaaacca atcatctggc
    32041 gtgcagttcc acaatggttt gcctcagttt ctaaattccg tcaagaaatc ttggacgaaa
    32101 ttgaaaaagt gaaattccac tcagaatggg gtaaagtccg tctttacaat atgatccgtg
    32161 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt cctatcttct
    32221 acgctgaaga tggtacagct atcatggtag ctgaaactat tgaacacgta gctcaacttt
    32281 ttgaagaaca tggttcaagc atttggtggg aacgtgatgc caaagacctc ttgccagaag
    32341 gatttactca tccaggttca ccaaacggcg agttcaaaaa agaaactgat atcatggacg
    32401 tttggtttga ctcaggttca tcatggaatg gagtggtggt aaaccgtcct gaattgactt
    32461 acccagccga cctttaccta gaaggttctg accaataccg tggttggttt aactcatcac
    32521 ttatcacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    32581 ttgcccttga tggtaaaggt gagaagatgt ctaaatctct tggaaatact attgctccaa
    32641 gcgatgttga aaaacaattc ggtgctgaaa tcttgcgtct ctgggtaaca agtgttgact
    32701 caagcaatga cgtgcgtatc tctatggata tcttgagcca agtttctgaa acttaccgta
    32761 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    32821 atacagtcgc ttacgatgag cttcgttcag ttgataagta catgacgatt cgctttaacc
    32881 agcttgtcaa gaccattcgt gatgcctatg cagactttga attcttgacg atctacaagg
    32941 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    33001 ttgtttacat tgaaggtgcc aaatcactgg aacgccgtca aatgcagact gtcttctatg
    33061 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    33121 tctggtcata tcttgagttt gaaacagaag acttcgtcca attgtcagaa ttaccagaag
    33181 ttcaaacttt tgctaaccaa gaagaaatct tggatacatg ggcagccttc atggactttc
    33241 gtggacaagc acaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc ggtaaatcac
    33301 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    33361 acagcaatgt agcacaactt ttgatcgtgt ctgagttgac catcgcagaa ggaccagctc
    33421 cagaagctgc ccttagcttc gaagatgtag ccttcacagt tgaacgtgct gctggtgaag
    33481 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtta
    33541 tctgtgatca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    33601 ttgaagagaa ataagattga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    33661 aattttatag tctattaaac gcattgtatc acgtttttga acacctgata tgatgcgttt
    33721 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    33781 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgg
    33841 taaatagtgt aatattttta caacaat
//
LOCUS       DAVLUM010000020        33773 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLUM010000020 DAVLUM010000000
VERSION     DAVLUM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.020"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(359..2086)
                     /gene="ezrA"
                     /locus_tag="VYN42_000769"
     CDS             complement(359..2086)
                     /gene="ezrA"
                     /locus_tag="VYN42_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1461872.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2168..4114)
                     /gene="gyrB"
                     /locus_tag="VYN42_000770"
     CDS             complement(2168..4114)
                     /gene="gyrB"
                     /locus_tag="VYN42_000770"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1461873.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALACYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4129..4692)
                     /locus_tag="VYN42_000771"
     CDS             complement(4129..4692)
                     /locus_tag="VYN42_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1461874.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4777..5331)
                     /locus_tag="VYN42_000772"
     CDS             complement(4777..5331)
                     /locus_tag="VYN42_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1461875.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5342..6565)
                     /locus_tag="VYN42_000773"
     CDS             complement(5342..6565)
                     /locus_tag="VYN42_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1461876.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6602..9052)
                     /locus_tag="VYN42_000774"
     CDS             complement(6602..9052)
                     /locus_tag="VYN42_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1461877.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLTQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9252..10181)
                     /locus_tag="VYN42_000775"
     CDS             complement(9252..10181)
                     /locus_tag="VYN42_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1461878.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMNRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10321..10608
                     /locus_tag="VYN42_000776"
     CDS             10321..10608
                     /locus_tag="VYN42_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1461879.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10642..11976)
                     /gene="ciaH"
                     /locus_tag="VYN42_000777"
     CDS             complement(10642..11976)
                     /gene="ciaH"
                     /locus_tag="VYN42_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1461880.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11966..12640)
                     /gene="ciaR"
                     /locus_tag="VYN42_000778"
     CDS             complement(11966..12640)
                     /gene="ciaR"
                     /locus_tag="VYN42_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1461881.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12749..15295)
                     /locus_tag="VYN42_000779"
     CDS             complement(12749..15295)
                     /locus_tag="VYN42_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1461882.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMILSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15418..15858)
                     /locus_tag="VYN42_000780"
     CDS             complement(15418..15858)
                     /locus_tag="VYN42_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1461883.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(15833..16702)
                     /locus_tag="VYN42_000781"
     CDS             complement(15833..16702)
                     /locus_tag="VYN42_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1461884.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16744..17472)
                     /locus_tag="VYN42_000782"
     CDS             complement(16744..17472)
                     /locus_tag="VYN42_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1461885.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILDSLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17480..17959)
                     /locus_tag="VYN42_000783"
     CDS             complement(17480..17959)
                     /locus_tag="VYN42_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1461886.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(17970..18668)
                     /locus_tag="VYN42_000784"
     CDS             complement(17970..18668)
                     /locus_tag="VYN42_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1461887.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18661..18927)
                     /locus_tag="VYN42_000785"
     CDS             complement(18661..18927)
                     /locus_tag="VYN42_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1461888.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(18993..19919)
                     /locus_tag="VYN42_000786"
     CDS             complement(18993..19919)
                     /locus_tag="VYN42_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1461889.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19994..20809)
                     /locus_tag="VYN42_000787"
     CDS             complement(19994..20809)
                     /locus_tag="VYN42_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461890.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPDPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFRGFKKIKWSEV"
     gene            complement(20813..21133)
                     /locus_tag="VYN42_000788"
     CDS             complement(20813..21133)
                     /locus_tag="VYN42_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1461891.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVKTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21475..21555)
                     /locus_tag="VYN42_000789"
                     /pseudo
     CDS             complement(21475..21555)
                     /locus_tag="VYN42_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21599..23596)
                     /gene="metG"
                     /locus_tag="VYN42_000790"
     CDS             complement(21599..23596)
                     /gene="metG"
                     /locus_tag="VYN42_000790"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1461892.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYAIALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23720..24979)
                     /locus_tag="VYN42_000791"
     CDS             complement(23720..24979)
                     /locus_tag="VYN42_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461893.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24981..25682)
                     /locus_tag="VYN42_000792"
     CDS             complement(24981..25682)
                     /locus_tag="VYN42_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461894.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25666..26865)
                     /locus_tag="VYN42_000793"
     CDS             complement(25666..26865)
                     /locus_tag="VYN42_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1461895.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KTDEATN"
     gene            27151..28497
                     /gene="gor"
                     /locus_tag="VYN42_000794"
     CDS             27151..28497
                     /gene="gor"
                     /locus_tag="VYN42_000794"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1461896.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28694..29230
                     /locus_tag="VYN42_000795"
     CDS             28694..29230
                     /locus_tag="VYN42_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1461897.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            29281..29367
                     /locus_tag="VYN42_000796"
                     /pseudo
     CDS             29281..29367
                     /locus_tag="VYN42_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29436..29651)
                     /locus_tag="VYN42_000797"
     CDS             complement(29436..29651)
                     /locus_tag="VYN42_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1461898.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29749..30069
                     /locus_tag="VYN42_000798"
     CDS             29749..30069
                     /locus_tag="VYN42_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461899.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30099..30437)
                     /locus_tag="VYN42_000799"
     CDS             complement(30099..30437)
                     /locus_tag="VYN42_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461900.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30449..31168)
                     /gene="trmD"
                     /locus_tag="VYN42_000800"
     CDS             complement(30449..31168)
                     /gene="trmD"
                     /locus_tag="VYN42_000800"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1461901.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31158..31676)
                     /gene="rimM"
                     /locus_tag="VYN42_000801"
     CDS             complement(31158..31676)
                     /gene="rimM"
                     /locus_tag="VYN42_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1461902.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31707..32495)
                     /locus_tag="VYN42_000802"
     CDS             complement(31707..32495)
                     /locus_tag="VYN42_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1461903.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(33072..33311)
                     /locus_tag="VYN42_000803"
     CDS             complement(33072..33311)
                     /locus_tag="VYN42_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1461904.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33331..33603)
                     /gene="rpsP"
                     /locus_tag="VYN42_000804"
     CDS             complement(33331..33603)
                     /gene="rpsP"
                     /locus_tag="VYN42_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1461905.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
BASE COUNT        10030 a         7391 c         5987 g        10365 t
ORIGIN      
        1 aggaactatc cgtgagttct ctagtctgga gatttttcaa tagacttcgt tattggacgg
       61 ttaccaagtt actcaaagta cagatttgaa gctgcagata agactgacga aatcacttta
      121 atactaaatg aaaatcaaaa agcaaactaa gaagctagcc tcaggctgta cttgagtacg
      181 gtaaggcgac gctgacgtga tttgaagaga ttttcgaaga gtataaaaca ctgttttgag
      241 gtggtggata aatcggctgg gtaaaaactc aatctcagga gaaaatgaag taaatctccc
      301 cacaactata gaaaaagatt tgattctgct cctcacacaa taaaatcttt ttcttttatt
      361 aaaaacgaat cgtttcacgt gttttctcat atgaggtaac aaagcgattg gttacaccag
      421 gctctgccac ttccaatgct tgagaaatct tgtcaaatga agcgtgataa tcaaattctt
      481 tttcaaaaat atctaaagct tcgttaaatg cttcttgaat gcgttcatca aatgagcgat
      541 agcggttaga atattgcaag agttgctctg tcaaagttgc atattgtaca atattataag
      601 tttccgtttc taaagcttcc atatcattcg ttgcaatttc aagaactcgg gtaacagatt
      661 caatgttaat cattttttgt tctaactcaa ccattaaatc ctcggtatta ttgcttgccg
      721 taaagaataa cttcaagaaa gtttgtggaa tacctggcag attgcgtttt tccatgtatc
      781 gcttgatagt atggagacga ttgacataaa cattggcctt ttgacgtgca ttaatatcat
      841 ctttctcaat ttgtgtcagg cgctcactaa ctgaaatttg ctcatcttca atatctttta
      901 gttgagtttg taaatcctca agattttctt caagaactga ataagcttgg gttggttctt
      961 cttgatttga agttacctca acaatagctg cctcaaaact ctctaattct gtctgaatac
     1021 gacgaacatg gcttgcagct gtctcaggaa gtaaataggt cttgttcaaa cgtgcaatat
     1081 cttctcccaa taaagtatta ttctctttca tatgttgaag gtaagttgga agagttgcaa
     1141 gtagattttc cactactttc tgagcagcaa tttctcgagt aaaaatatca tacaaggcat
     1201 tgatttcctc ttgtgcctgt ccattctcat attcggcatt atccaattcc aactgacgaa
     1261 tattctcttg gtttttcttg aatgcttcat aaagcaagtg gaaacgcgct tcaatatccg
     1321 tttcaacaaa atgataatta gcatcaatta gtttacgata accggcttcc aaatcctgta
     1381 attgatctgg caattctgta gaaagcgtcg taaccaaggc tggaacacga tccacaatat
     1441 gacttaaggc caaaatgtga ttttctgtat tatccaaaat cactgcggct tccacagggt
     1501 cacccgatga attcaaggtt acaaattgtg aaaattcaga ttggatattt tctaattgtt
     1561 tttcaatttc atccaaggct tgaccatact gttctgaatt ttcagcaact ctatgctgaa
     1621 gttcctcaaa taaatccaaa gcatgaagaa cacgaccact atttttagat tcttgcttct
     1681 ctaagtctgc caaagcattg cgaattgccg caatatcttc ttcaatcaaa gtaatttgac
     1741 tctcaatttg gtcaatttga tgactggcct tgagaaaacg aaatgaatgg ttatagcctt
     1801 ctgcttcaaa gagattattt tcaatatcgg caaaagagtt gagagataaa tcgacccatt
     1861 tttgattcca ttcacggaaa gccacttgac tttgtccaat caagtgcata ttttttacag
     1921 cttctacttc atcatttact ggaagattgt atagttcttc ttttctttct tctagcgcct
     1981 ctaatctccc ctcgtttcgc ttacgtagaa agattgccac tacataagcc agaactaaaa
     2041 tgactgcaat tgcaaccatt aaataaatta gttgtccatt agacatatca aactcctttt
     2101 ttacttgaaa caatcgtaac gattatatca tattttttag accaagggaa ctacttctcc
     2161 ctatttttta gacatcaagt gtactataga cagcattttc ttcgataaac tcacgacgag
     2221 gctctactcg atcccccatc aacatatcaa agattttatc tgcttctgca gcatcatcta
     2281 cagaaactct agccatcaag cgatgttcgg gatccatggt tgtttcccac agctgatgat
     2341 cgtccatttc acctagcccc ttataacgct gaatagtcgg tttggtacga ccttcactat
     2401 aacaggctaa agcttcttgg agtttgattt cttgatctgc acccggctgg atatattctt
     2461 taatctcgct tccaaccttg acaccataga ttggtggttg ggcaatataa acataaccag
     2521 cttctaggat tggtttcata taacgataaa tcaaggttaa aagaagggta cgaatatggg
     2581 ctccatcgac atcggcatcg gtcatcaaaa cgagtttttg gtaacgggct ttcgaaacat
     2641 caaattctgc gccaaatcct gttcccatgg ctgtgaaaag actacgaatt tcttcgttag
     2701 ctagaatctt atccatactt gctttttcaa cgttcaaaat cttaccgcga attggaagga
     2761 tagcctgaaa ctcacggtta cgaccagatt tggctgatcc accagctgag tctccttcga
     2821 cgatgaagag ttctgtttca gcagggttat tagaagaaca gtctgctagt ttccctggaa
     2881 ggttggaaat ttccaaacca gattttttac gtgtgacttc acgcgcacgc ttggcagcca
     2941 cacgagcctt ggcagctaaa atcccttttt ccacgatacg tttggcaatc tgtggatttt
     3001 ccatgaggaa atcggagaag gcttcactga agaggcgatt ggtaatcttg accacttcgc
     3061 tatttcccaa tttggtcttg gtttgtcctt caaactgtgg atttgggtgt ttaactgaga
     3121 taactgcagt taatccttcg cgaacatctt cccctgttaa attatcttca ttgtctttca
     3181 gtaacttatt cttacgagca taatcattga taacacgagt cagtgccgta cggaaacctt
     3241 gttcatgcgt tccaccttca tgggtatgaa tattattggc gaaactcatg acattttcat
     3301 ggtaacctgt tgtgtactgc atggctacct caactgtaat atcatccatc tcaccgtctg
     3361 tatagattgg tgtatcaaag attacatcct tgttctcgtt gatatattca acgtaactag
     3421 caatcccacc ttcataatga taatgcttgg tttgttccaa accttggcgc ttatcagtga
     3481 tggaaatttg aagaccgcga tttagaaagg ccaactcttg aatccgttta tttaatttat
     3541 caaaatcaaa gattgttgtt tcagtgaaaa tttctgggtc cggtgtgaag tgaaccgttg
     3601 ttccagttct atctgtatcc ccaaccacct caaggtctgc aacaacatga ccacgacggt
     3661 attcttggta atgaatctta ccgtttttat ggacatgaac gtctaattga gtggaaaggg
     3721 cattaactac tgacgacccc accccgtgaa gaccacctga aaccttgtat ccaccaccgc
     3781 cgaactttcc tccagcatga aggactgtaa agacggtctc aacagcagga cggcctgttt
     3841 tttcctgaat atcgactggg ataccacgcc catcatccac aacagtaatc gaatcatctg
     3901 gctcaataaa aacttgaata tggctggcaa atcctgccaa ggcctcgtca attgagttat
     3961 caacaatttc ccagactaga tggtgaagac cttcttttga ggttgatcca atgtacatcc
     4021 ctggacgcat acgaacagcc tctaagccct ctaaaacttg aatttgactg gcatcataat
     4081 cctgtgcctg cagatttttg atttcttctg tcatcttatt cctttttctt atatgtctaa
     4141 tacttgtctt aaattcacga tactggtaaa caagtgggta tcaagtcctg cagcttgacc
     4201 tgcttcgata tcaatcggcc gatcaccaat gacaagacca gagctaatct gatacttttc
     4261 tcttaaataa agcatggatt cgggatttgg ctttctctta aagcctgagc tagaagtcac
     4321 cacttctgta aaataagctg ctatagaggt tttttctaaa atttccaaaa cctgatcatt
     4381 tcgatgagag accaaaaaat gacggccacc ttgatttaaa atgtcttcca ataggtcaga
     4441 aactccttca aataaaatcg ggtgttcaag ctctctggct tcattttcct tgtacttttc
     4501 taaaaaattc tctaaattgg gagcgaatgt ctcaatcgca aaaggagtag aaacctttaa
     4561 agcttgatag acactgtcat ggtcttgtgt gataccatac agtgccaatg tttcaacaaa
     4621 tgcagctgtt gaagtttcat aattatccag taaagttcca cctaaatccc agatgtaatc
     4681 gtgatatttc atacccttca ttatagcatt tttttatgaa aaaagcgatg atttccctga
     4741 gttttccaca taaaaaacga gagaataact cccgttttac tgatttttac caaagacatc
     4801 tcgatagagc attcctgttc gtaaactctc tgcgtcccct cctagttgct ccaccaactc
     4861 gtaggcaaag gcaagggctg ttgaaggacc ccgactggtt gtcaactgac catctaccac
     4921 tactgtttcc ttgacgtagt gaccatcaag gatttgctct tgaacgccgt cataacaagt
     4981 gtatcgctta tttttcaata tctctgcttg attgagggca attggtgccg cacaaatggc
     5041 tgctagtttc tttccttctt gctcgaagct ttgcaattct tgaatcaagg tctgattatc
     5101 acgtaaatgt gcagaaccag gcatacctcc aggaagaaca atcatatcat agtctgataa
     5161 atctccatca aagacatgat ctgctcttac ttggattgca tgcgaacccg ttacttgctc
     5221 ttcaaaacca accatatcac atgtgatatt ggctcgacgc aagacatcta caactgtcaa
     5281 ggcttcaatt tcttcaaagc cctgagctaa cataactgct acttttacca tgattttctc
     5341 cttatttaat ttgttttaat acaacctttt tccgtttgaa tgggactttt ccgctctttt
     5401 cttcagctag attagtctgg taactcatcg ataaaagcaa accaacacca atcagattac
     5461 tgataatagc tgatccccct tgcgaaatga aaggcaaggg aatccccgtc aaaggaagta
     5521 gtccagtcac agcaccgata ttctcaaaga tgtggaagag caacatcata atcaaacctg
     5581 tggaaatata agtgtagaac tggttatttg atttaagagt aatcttcaac atacggtaaa
     5641 tcaacatgag atagagggca ataaccagga cagagccaat aaagccaaaa tcttctgcaa
     5701 taaccgtaaa aatcatatct gactctcgaa ctgggataag cagattcgaa gcattaaatc
     5761 cctgaccaaa taagccacca ctcccaatgg caatctgccc ttgagcctgc tggtaagtcg
     5821 ttgtttgggc aaactcaaag ggattgagcc aagccaaaat ccgattaatt tggtaggtcg
     5881 gcattccaat ctggtgaaga aaagctcgtc cgtccttgct aataaagata gctaagaaac
     5941 cagcaactcc tgttacagca gtcacaaata ctgggataat aattttccaa gaaacccctg
     6001 ataataaaac gattcctgag aaaatggcta caaaaaccaa agccgtcccc aagtcacttt
     6061 gaagtgctaa aagaactagg actggaatgg taaagagaat catccagaaa attaacaaaa
     6121 agtccagcgg aaccgtgcgt ctccattcct tatgtttctt tgtaaattgg acaatgacac
     6181 gagccaacat gaggatatag gatatcttca taaattctga cggttggaat agggtaattc
     6241 catttattga tacccagttt ttggcacccg ttgatgcaac taagcttgga ttataaaata
     6301 caatcggcaa gatcataagt cccaagccta aaatatatag aaagggggtc accttccaaa
     6361 gaaattctgt attaaaaagc atgaccacaa aaccaatcac aagccccaag gcaatccagg
     6421 cgacctgctg ccctaaaatg ggcagaatat tattgggata atcatgacta acggctatat
     6481 agatagccac cacaccgatg accagtagaa aaaatactgg caagagcaaa ctgtaatcga
     6541 ctcttgagtc gagagaacgt ttcatatata ctaaccttat actttcatac aatactattt
     6601 atcaaagttc attaaaaaat ctatcaatag cctcgtcaac ttcggatcga gagatggttt
     6661 taacagtcgc ttcttctgct agagatgcta ctatttgttt gccgtatcgt tttccgacga
     6721 ttctcctatc caaaataaga gttaaggaac gttggtattc acgtctcata cttcttccca
     6781 aagcctgttt taaacgaata atggccattg gcaattgata atcataaaag gcatttttcc
     6841 cttcttgatt cagttcttga ttaatctttt tcgtcaaggg ttcttgagga ttttggaaag
     6901 gaagcctcgg tacaacttga atcacaaaag gatggcttga aaaatcaact ccctcccaga
     6961 aacttgctgc accaagcaag atttgttgtt cacctttttc aaagcgtttc tttagctgat
     7021 gaacatcccc atttttatac tgtgtcaagt ggctaactgt aagtaaatcc gatactgcta
     7081 gaagcatgtc tttagcggta aagagaacca aaatcggttg ctggaaagct tgaatttcca
     7141 ctagtaaagc agctacctct ctggcataga cttctaagga ggtttctgtt accagaggga
     7201 aatctttgac cataaccact tcttgttcct gttttccccg agattcaatc ttgacaaatt
     7261 tggcttcagg atagcctaaa aggtctgcca aagaaaccct ctgactaatc tcaagagtag
     7321 ccgatactcc caagacttgg caactctcag gaagtaaaga ggacagaaga gtacggcctg
     7381 attttgtaga agaaatctga attttctttt gactcgtttc agttacttca agccagtaat
     7441 caccttcagc tgtaaaatag cgaaccagct catcaaagcc ttctacttct aattctgaaa
     7501 aatactgatg gagattatcc agagaatcta agatattttt cctagatttg ccagactgaa
     7561 attgttctat caagtagaga cactcaaagc gaatactttc tagtatccgt tgttgaaccc
     7621 tgttttcttc tcctactaaa gccttatcaa ttaaatcgat aatagattgt atatcgtagg
     7681 tctcttgaag cagattttct agagctaaca aaatcttttg gacttcatca ataatcagta
     7741 aacggtcact gacaaattca ggattatctt caagtctggt cacgagatag gcatgattag
     7801 tcactaaaag cttgcaagtc tctgcccttt cttgactacg tttccaaaaa tcttccgtca
     7861 caaataagct ctgggatgat aaattcccat catgacgaag gtctgctaga aaatgttggt
     7921 aacggtagag ttgcccgatt tcatccaaat ctcctgtctc tgtctcagta agccagacca
     7981 agacttgcat tttaaagcgt ctaaataagc gattttcatc attttcctgc aaggaatgat
     8041 aaaaggcatc caacttcaga taattttgtg gtccctttaa gctatgaata tctgtatgga
     8101 acacttcctt gagacgttta ccttcttctt ccatgatttg attttgaaga atctttgtcg
     8161 gaacactaag aacaatttgt cgctctttgg attgagataa agcgggtaag agatagccat
     8221 aggttttccc aatccctgtc ggcgcttgaa tcagagagac aggttcatct ttcaatagca
     8281 agccaacctc tttagcaaaa ctttcttgtt cctccctcac ttcaaggttc aacagagaaa
     8341 tatttttaga aaagtcttga gatagttttc gtagctccag agaagctgcc gttttcttaa
     8401 aatacagacc ttgaacttgg accaagtctg gagaactcag gatagattgg ttgcgataag
     8461 tttcctcaat aaccaggtag gactcatata ggagagcgtc agccatttcc agcaagcgtt
     8521 ccaagagacc cttaggaagc tgggtcatct tttcccgtaa aaaaagaagt aattctgctg
     8581 tagcttgggc atctgaaagg gctgtgtgtg cgtgtttaag aggaattcct aattctcgac
     8641 acaaaatcgg caagctatat ttttccagtt cagggaaaaa gacctgggcc aattcgaccg
     8701 tatcaacacg agggtttctt agctcatagc cttcaaaaaa taaattttcc gccaagagat
     8761 tagcatcaaa ctgaacatta tgggctacaa aaatcccatc ctccaccaag tcaaatattt
     8821 ttctggcaac ttgcgaaaaa tcaggtgctt gcgccagacg ttggtctgtc aatcctgtca
     8881 gttctttgat atgagcatcc aagggttcat gtggattgac atccgtcgta tagtgatcga
     8941 cgatttctcc gtcctcaatc acgacaattc ccacttggat aattttagcc ttactacctg
     9001 tgctagttgc ctctaaatcc accacaacat agcgattacc aatcgttttc attataaaaa
     9061 attataccaa aaaaagggcc atttggcacc tgcaaacata ggataatttt caaactcaag
     9121 aacactactt ttcttaaaaa tcccatcgaa tagagcattc tagcctgctg atttttataa
     9181 aatagtgaag aaatacgaaa aattgagaga agaaatgttt gcatcttcct tctctcaacg
     9241 aatcatgtat tttatctaac catgtcagga tcgtagtcat aaaatcctgt atcaaggaaa
     9301 cggtttttag ggtgaagttt acgaacttct tcatccagca agaaggcttg atcatggcta
     9361 aagttgccct cttgaatcaa gttacgcgct tggataaaga gttttgcaat ctcaacaaag
     9421 ttctgaccag gagtgtagag cccttctagt ttccagcgag taaagccatg ctccaccaat
     9481 tctgttaatt tgatcatcaa atcaaggtca ttgttggcaa agatatgggt cccatgatta
     9541 tcttcaaaaa tggaatagtg gctctctgga tcacttggct cagccaagaa gaggtcacgt
     9601 ttatgcgtct tttcatcatc gatatgtgta aagttatagt agttttgcaa gagcggacgt
     9661 ttagaatgat ggatgacact agcaccgtaa accaaaactt cagcaggaat ttccaaaatt
     9721 tctggcattt tgaaaagttc agctgatgga atttcacgcg ccaaaacagc ctcagatgcg
     9781 ccagcctttt gtccccagaa gttaatctga cgactgctag ttaccatggt tgaagcatcg
     9841 tagatggtct taaatgaata accatcgcgg ttaactacgt aaaagacgcc tgcatcccca
     9901 atcgtaatat agtctgtctt gatttcttcc aagaagtcta agaaaggctt gatacggttc
     9961 atcatatctt ggtgcatgag agcattgacc gcaacgatca attccttacc agcatcatga
    10021 accaacttag cgatttcacg taattggtca taactaaagg tcgttggcag acgaaggcca
    10081 aaatctttct caccgacata gatacggtct acgccagctt cgagtagttg ttcaacttgt
    10141 tcaatacttt cagcagttgc tgtaatgaca atcttttcca taagaaaaat tataccacat
    10201 ttctccaaaa tcagccatgc tttgaaaatg aaaagggact ttattctttt tgtaaccttt
    10261 ctgtaataat tctctgccga aaaaatgata aaataggtat gtactgttaa ggagagaatc
    10321 atgcccgtaa gaaaattaca atcctatgag gtagactatc aagaagaatt aaaccagcag
    10381 cttcctcatt accaagctta tacacctgaa gcgcaatctg atgccaatct caaggaaatc
    10441 ctatttttta ttaatatcgc tgttttttgt atctgtattg ctatctttag ctttatcttt
    10501 ttggcattaa aattatcaac tgctcttgcc tttgccgcag caatcggatt cagcttactt
    10561 gttttaaaag ttcaacggtc tattatcaaa cgaaaacgta gaagataaat ccaaaatatc
    10621 gccccaattg gagcgatatt tttatttttt ctttttagat ggtgtctgaa tggcaatctt
    10681 cacttcaaag attgttccct tgggtttatt atctttgaca gtaacagttc cttttagagc
    10741 atctacaatt tgcttggcta gggataatcc taaaccaaaa ccaccttttt gccgggttct
    10801 agccttgtct actcgataaa aacggtcaaa aattttcttt ttatcttctg tcgaaatacc
    10861 gattccatta tcagaaacaa gtaaataaag attgcgatcg gtcgccgaga taagaaaatc
    10921 aatttcacca tcctcctcag tatacttgac ggcattatcg aaaagaatgg tcatcagttg
    10981 tttcagaaga agctgatctg tgacaattgt tcgatggata cgattttcaa aacggaagac
    11041 acgattattt tccgaagcaa tcatctcgta gtttgtgaaa gttgtattaa aaaagctagt
    11101 tggaacttct gcaagctccg gcttaatccc atcatctctc cgagctaagt tcagcaagct
    11161 tgtcgttaaa aaacgcatat ttcggacttc ttccaaactc gatgcaatgc tttcgctcac
    11221 atccataatg gtagcttctg gcttacgaaa aagggtctct aagcgatttt gcaaaactgc
    11281 gagtggagtt cgtaactcat gactggcatt ttccacaaaa gactgttgct tctgcatact
    11341 ctcaagcagg ggcctaacac tgaccctagc tagatagaga ctggcaagta aagacaaaat
    11401 ccagaaacta gccatcacga ccacaatcaa ttgctcatgc ttttgactag cctgctccaa
    11461 ctgactggta ttaatcaaga cagcagcata cttgatattg gttgaaaccg aactaatatt
    11521 ggtctccatc aaaatcacac gatagatttc ttcctgccca tagctattaa aaacctgaat
    11581 ctggtagata tgtcctagtt ctttcttttc taacttaatc ttatccaagc ccaaaaatcg
    11641 atttccagaa agaagttgag taaagtcttt atcaaagaga atgacttccg tattggaact
    11701 gacattaggt tttatttcta ctttactagc gtccgcccta gcattttcta aatctttaat
    11761 ctcttctgtt gccctattta tagccagctg aataactgct tgaggatttt cactcagtcc
    11821 atgaagctta tcgtccaccg aagtataaag actcgaatgc atgacttgta aaataatcag
    11881 agtcattgta gaaaaaatca gggtgaagac accgaagttg cggataaaat aactaaagtc
    11941 atccgcatac catgtttttt taagtttact gaacatcttt taaaagatac ccaacactac
    12001 gcaaggtttg caaattctct gcaaaagtgg ttccctttaa tttcttacgg acttttgaaa
    12061 catagacttc gacaaccgaa atcgttgtat cactatcaaa tccccataga cggtcaaaaa
    12121 tctgcgtctt aggcaaaatc acattttgat tttgaaggaa ataaactagt aaatcgaact
    12181 ctttccccag caattcgaca ggagtatctt caactttaac ggtattggtt gataaattaa
    12241 ccacgatatt cccataagtc aaggtgtttt cattaaactt ccctgaacgt ttgagaaggg
    12301 cctgaatccg cattttaagt tcttctaggt agaaaggttt ggtcagataa tcatccgctc
    12361 ccagttcaaa tccatgtccc ttgtcatcca aactttcctt ggcagtcata atcagaactg
    12421 gtgtcgtaat tcccttttca cgcaattctt ttaagacttg gaaaccattt ttttctggca
    12481 acatcaaatc cagcaaaatc aagtcataga caccactctc agcttcgtag agaccttctt
    12541 ctccatcaaa tacctgcata acatccgcaa aatcgtctaa aaagtcaaat actgaatttg
    12601 acagacctag gtcatcctca accaataaga tttttatcat gagaaactcc tccttattaa
    12661 aactattata ccaaatttgc cttaaaaaaa actcaactct ctgcatttta catgagatag
    12721 ctgagttttc tttttatttt aggcttattt atgcatttcc gtattgaaga acaactgctt
    12781 cgactgcagc tttttcacgg ctaatcaagt caacacgcgc tgcaatttcc ttgattccca
    12841 taccgatgtt acggctaaga gcaaggtcag aaagttgcgg ttcaaagaac tccttgtatt
    12901 ccgccaagcg ttgctgagtc ttaaatacat gagcaggaag gataacaaag ctatcaaagc
    12961 tcatatctcc tccaagggct gccttaatcc aagcccagtt ttcacgcgcc caagaccaag
    13021 ctgttttctg agttgcttga tgagctagga attggtaata ccaagcagac aagtcctgtg
    13081 gtttgaccac aaatttgtcc ttccaagaag taatcaagtt ttggatatta tccgcatctg
    13141 tactgtatgc aagagctgct gccaactggc gtttaaagac agcatctgtt gcgtgagtat
    13201 aagtatcaag ataaagtgct aacaagtctt tagtctcatg atgtttcatc tcattaatca
    13261 gaacttgtga acgaatagct gctgggagtc ctgcaagatt ctccttgtgt gttgcgaaga
    13321 tttggctagc gacttgacta gcttctgcat catttgagag aatcatcatc gaaacagcca
    13381 gctgacgaac caattcatcc tcatctgatt ctccgtcttt agcttcaaaa ccaagacggt
    13441 catagttatg acgagccaat ttagcaacca gtcctttgaa ggctgtttca gcatccgttc
    13501 cttcatcaat aaagcgctca agggctgaaa tcacttgaga aacagctgaa accaccagat
    13561 aagactcttc cttagcaagt ttatcaagaa ctggaagcaa gtctgcataa gaaatgtgcc
    13621 ctgcctcagc caacaaacga cgttcttgaa caatttgcag tttgcttgtg ttatcaagtg
    13681 tctctagctc agcaagaaca gcttctaaca agtctccttg atagtcggta atatagtggg
    13741 cagtattttc agtgttgaga cgaagagctc cttcattctc agcaagaaga gctgcgtagc
    13801 cagggatttc gatactttca gtttcgagtg tatcaggcaa gcctttccag ttgctattga
    13861 ggggcaccac ccagagacgg ttcttgtctt cgttctcacc gatgaagaat tgtttttgtg
    13921 aaatcttcaa gacatcattt tcaactttga cagtaagaac tgggtaacca ggctgttcca
    13981 accaagaatc catgaaggct gcgacatcac gtcctgacgc ttgaccaagg gcatcccaaa
    14041 ggtcactacc aatggtgttg ctgtattggt gtttttcaaa gtaggcatgc aaacctttag
    14101 caaaatcagc atctcctagc caacggcgaa gcatgtgcat gagacggctt cctttggcat
    14161 agacgatagc gccgtcaaag agtgtattga tttcatctgg atgtttaact tcgacgtgga
    14221 cagactgaac gccatcagta gcgtcacgtt caagagcaag aggtactcca cctgtttgga
    14281 aatcttcaaa gatattccag cttggttcga tggtatccac acagacgtat tccatcatat
    14341 tagcgaaact ttcattgagc caaaggtcat cccaccattt catagtcacg aggttcccaa
    14401 accattggtg agccaattca tgggccacaa caagggcaac ttgttgacgg ctagcaaatg
    14461 tagagttctc atcgacaacc aagtaaactt cacggtaggt cacaagaccc cagttttcca
    14521 tagcaccagc tgagaagtca ggaagggcga tgtggagaga ttgaggaatt ggatacttaa
    14581 ctccatagta atcttcgtaa aactcgatag agcgaacagc gatatccagt gagaaatcaa
    14641 gatttgaaag tggatgtgct ttggttgagt agacacctac cagggtacca tttttagttt
    14701 tagcggtcac cccttgcaaa tcaccagcaa caaaggccaa caagtaagaa gacatgcgag
    14761 gtgttgtctc aaacttccag atacctgttt ccttacggtt ttcaacatcg atttctggca
    14821 tgtttgacaa ggccaattca ccttctgctt ggtcaaagcg aagagagagg tcaaaagttg
    14881 ctttggcttc aggctcatcc acacatggga aagcttcgcg cgcaaaatgg ctctcgaact
    14941 gagtagacaa gacctccttc ttgactccat caactgtata ataagaaggg taaatccctg
    15001 tcatgttgtc tgtaatttta ccagaaaagg caagaaccaa ttcaacttga ccagcctcag
    15061 ccaattcgat atgaagggct tcattgtcat ggtcaactgt aaatggacga gcttgacctg
    15121 caacttctac agaggtgatt tccaagtctt tttggtggag ggagatgcgg tcactctgtg
    15181 cttgaccagt gatggtcact ttcccagaaa aagtcttggt ctcacgactc aaatctaaaa
    15241 ataaatcata atgttcagga acaaattgct taataaaatg ttcaactgct tgcatagttt
    15301 tctcctattc taagtttaag agctgctgct cttcttcaaa caaacttatt atatcatatt
    15361 ttgcttgaaa aaaaaggatt ggacagcgat ttccaaaact ttcttccttc taatagtcta
    15421 cagtgggtag accttgcgaa attcttctaa aacaaccttg ctttcagatg taaaagtcag
    15481 ccctacttca cccaaacagt ctgtgaaaaa gtcctcatga acctggcgcc aataggcaag
    15541 tgatttgtct ccctcacctt ccttaaaggc atgttgcgca gaaacttgat tgaagagttc
    15601 aacagaaacc tttgtaattt cgacaatgca gacagactga ttttgactat ctaaaatgac
    15661 atcgaaggtc cctacttggg gaagtggttc gtcttctagt acatagaggt cataggctga
    15721 tgctgttgct gtcttttctc ctttaaacac caaatccgct aaaaggtctg gttcaactcc
    15781 aaaagcccaa gcatcgattt catctccgat caaaggattg atttgcttgt atttattcca
    15841 catttcttgc ggtatcatgg gtactccttt gtaatttttt actttcttct tttatgtgtt
    15901 taagatgatc tggatggtca atctctaaat caaaaatctc tggaatagaa ctgtagtgga
    15961 taatgcactt gatacccaac tgattcattt tttgtatgaa agaagtattc agatagcctg
    16021 ctacagcaaa attaatcttg ttctttcttg ctttatcctg catatctctt agcatatcta
    16081 acattattgg actttccata tcatgccatt gactgtttct catagtcgca aaaacaaagg
    16141 aagtcaaatc attcattcca actacaatct ttgaaatgcc cgtttccagt atactagata
    16201 agtcaaaata cgctgacggt aattcaatca tcgttccgac tttcccagta aagccatact
    16261 gacgcaatac tgtaatagct tgttttaatt ggtcggcatc attgacaaaa ggaaagataa
    16321 cagatagatt ggggttggtt tgataaactt ctgtaacgac atgtgcttca gcctgaaatt
    16381 catccaaaca cgccagtaaa cgcctggttc ctctatagcc aaacaaggga tgcccttcgt
    16441 caaaaaactc tttagtcccc actaaacaat tggcttctgt attcgttaat tcagtaaaac
    16501 gataccaaac ttcttcatct gagtacaggg agcagatagt ctctagataa tcttttacaa
    16561 attgctgaca acttgctaat atgatgtttt gattaagctc tctcaacaaa tattccccac
    16621 gaatcatgcc gacgtggtga aatagttgag gataaatttt ttcaagaatt ttttcgccac
    16681 taagggcaag ttgatttctc atagccattc acctcatctt aaaagataca atatcatata
    16741 taattatatc aaaatttcct ctagttcaaa agcttcataa ggttcagata actcatatcc
    16801 taaaaattct gctacttttt tggaagcctc attatgagca tcccaaagtg gaaacatatc
    16861 tctatttaaa ctatctagaa tcattgcagc accaagcttt ttagcaaatc catttccttg
    16921 ttcgtttggt ctagttgcaa cttccacttc aactgcttta cggtaaacta accctgagga
    16981 aatcccagca atcagttcat tatttttaag aatcacaaag ccaaatccac cttttaaaac
    17041 aaaatcctga taggactcaa aatccccctg taaatcctgt gaccattctt ccgtagaaaa
    17101 gcagttataa atatgattat caataggcac aatattgtaa ccttcctcta aatgagtaac
    17161 tagattattt aaaaattcaa cttgaaaatt tgccttatct ttaaaagaat agcgagtaaa
    17221 agaatttagc cccacttttc gatgcagaaa atcttgccaa ttagtatttt ctgaaataat
    17281 aatcttataa tctaaaccat attttctaac aaaatcttcc caaaatctgg aatccaactc
    17341 ccctgctagg tatagaaaat tcccaacatc ataaaagctt gttgtcctat cattgtttcg
    17401 gtagacagtt ccaatttgag atttaagacc atagagaacc atatttttct tccatgtttt
    17461 aaatagttcc attatccctc tacttcacct tccaattcat gtaagaagtc ttgtccagtt
    17521 ctggaaatcc taataattca gacttaacct tcaagactaa tggcgatgca ttttcttctg
    17581 taatctcttg aatatccatc caaatatatc caagtgaatc attcgcacca tcagacacag
    17641 cttccgaagt cgtaacttga ggtgcactct cattcatttc aacatcatac aaggccatga
    17701 catggtgaac cataaaattt gttaactctt ctctgacgaa aacatcgtag attcgaggat
    17761 tagagtagct tctaacagta aatcccgtct cttccataac ttctctagtc agcgtttccg
    17821 tcagtccttc accaagttgc tgactgcctc caggtagatc ataccgatgt tgataagggc
    17881 ctctcgtttt ttcaatgcaa agtaactttc cattttcaaa gcaaacacag tagaccccaa
    17941 agtgattttt gatttccatc caactcctcc tacttcaaag accagccacc atctattgtc
    18001 aagatttgtc cttgcatggc gctcgctttt ccacttgcta aaaaaagact aagctctgct
    18061 atttcctctg gctcaatcca gcgcttgatt ggggtttcac tagccaccca gtcagccaaa
    18121 ccacctggtt caaaatccgc agcggtcata gctgtcttga ctgctcctgg agcgatacca
    18181 aagacctgaa tcccagcttc agcatagtct agagccaact gcttggtgaa gccagccaag
    18241 gcatgcttgg atgaagtata ggcgtgacca cctccacctg ctaggctaga agcaatggaa
    18301 cacatattga tgatgattcc ctttttattt tccagcattt gtgtcaaata ataccgagtc
    18361 aactctactg gaataatgta gttgatttca aaaatctctt gaatgtcctg cgccgtttgt
    18421 tccaacagtg gtttgtaatc atccaaaact ccagcagtat tacacaaaac atccacctga
    18481 gggcaccagt caaaaatagg ttccaagtcc aaggtcaaat ctctctgtaa aaagtgaaaa
    18541 tcaccctcta agagtggctt ttcaccttgg tcaactccat aaacttgata gcccttctct
    18601 aaaaagaggc gagcttgagc caatccgatc cctgaactca ctcctgtaat gagtacacgt
    18661 ttagtcatgc acttctaccc aatccgttgc caaaacatca caaactgtcg ggctccacat
    18721 ggaaaaacct tctccttcgc cagaaacgtt gattaggaaa taaggtgtca tttcaagtgc
    18781 aagcccattt tgctcgatgg tatcaaagag ttggacatag ttttccgcac ctccccaacc
    18841 agttcgtaca tattttctct tagcctttaa cccaggcagg atctcttcaa atgtcatgtt
    18901 tttctccttt aattctacat tcttcattta attatagcaa aaaaccgctt tatacggctt
    18961 tttgaatgtg agttattcaa acctgctact acttacggca aattattccc tgcagcaaga
    19021 taaatttcat accattcttt tcttgttaag ctaaagtttg ccgctcggct aacttctctc
    19081 aagtgcttag gatttgttgt acctacgact gcctgcattt ttgctggata acgcaatatc
    19141 caagaaatgg caatagttga agaggttact ccatatttaa tagctaaacg atcaagtact
    19201 tgatttaaag cttgaaattt ctcatttcca acaaaattcc ctttaaaata cccgaattgc
    19261 aagacagacc atgcttgaat gaccacatcg tgtaatttgc aatattcaaa aatgctgcca
    19321 tctcgcatag ctgcttgact atcttccata ttaacatgaa aagctgattc aaatcctgga
    19381 gtaaaagccg cactcaattg tagctgatta acagctaacg gctgcttgac atctttttta
    19441 agcaactcca tcatcatagg attttgatta gaaactccaa aatctcgaac tttaccttgt
    19501 ttataaagga gatcaaaggc ttctgctact tggtcagatt ccatcaaagc atctggtcga
    19561 tgaaggagca agctatctag atgatcaatc ttcaatcttt gcaaaatacc gtctactgat
    19621 tttataatat agtccttaga aaaatcaaaa taggtaaatt cttcaatgcg aatgccacat
    19681 ttggactgaa tccacatctt ttctcttaaa tctggacgat tttttaggac aagacctaac
    19741 agttcttcac aacgaccacg accataaata tcagccaagt cgaaggcatt gattccaaca
    19801 gaaagtgctg tttctacaag ctcttcaact tcttttacag acttatcttt tattctcatc
    19861 attccgagaa caatttctga taattctttg tcatcttgac caagagttat gtatctcatc
    19921 aaatttttct cctttaattt ctaacattct tcccttcatt ataacaaaaa aacgctttgc
    19981 aacggctttt tgactatact tcactccatt ttatcttctt aaacccacgg aacaagagaa
    20041 aaatgccaat aaagaggaca gctaaaggaa taacttttgt aaggaaaaca tttgaaattc
    20101 ccatccactc ataataacgg agcagagaac ccaccacaag atgggcaata atcatactga
    20161 caaatggacg aaagaccgct tctttccaat tccaaatacc gataactagc gaaatcgtaa
    20221 agacagacaa actatcccag ggatccggaa tataaaaggc tccttcttgt atgaagcttg
    20281 ccattcctac atatcctaaa acaactagaa gaactatagt cccaacaaca atgtaagtgc
    20341 caattttcat tttaggagaa tcttggacta aacttcttcg taaaattgtg gccacaagtc
    20401 caaatccaat cagaaaaata agaagttgcc ctaaaaatgt gagcaaattg actgttaaga
    20461 gaggaccttt agaaaaatca cttagtagtt gataataacg taataccgcc aggacaagaa
    20521 ttggcgtcaa aagggactct ttgatagaac tgcgaggtgc tcccttgaga atctctttca
    20581 ttattttttt aggattctta cctagataat cctctgcact catgccatct cgttctgctt
    20641 ctgagaaatc tagcatcatc aaatagatct gctctctgag atagtcttca tcatagagaa
    20701 atccagcaag attaaaactt tcccacaact cctcaaaata cttttgattc tcctcagaaa
    20761 actcatgtag caaagcgctt gtttcttcgt aatacttcat tttcttcatg gtttaacccc
    20821 cattcttaat cccttctact ttttgactca aatcgtccca ttgttgccaa aagactgaga
    20881 cacgctcttc tccttctttc attaatgaaa aatacttccg atctggacca tctggcgacg
    20941 ggcgcatgtc gcctcttatc cattgatttt tttctaactt ttgcaacaaa ggataaatag
    21001 ttcctggaac gatagtatca aatccagcct ctcgcaaagt cttaaccaac tcataaccat
    21061 accgctcttt ttgaccaatc atatccaaga cacaaccttc aagaacacct tttaatagct
    21121 gagtttcttt catcacttct cccttctaat ctattttgta atacctacta gtaacttcac
    21181 ctatagtata ttacttctac actagtttgt aaagcataat agttaatact cttcgaaaat
    21241 ctcttcaaac cacgtcagcg tcgccctacc gtatgtatgg ttactgactt cgtcagtttc
    21301 atctacaacc tcaaaacagt gttttgagct gacttcgtca gtttcatcta caacctcaaa
    21361 acagtgtttt gagctgactt cgtcagtttc atctacaacc tcaaagcagt gctttgagct
    21421 gacttcgtca gtttcatcta caacctcaaa aacatgtttt gagctgactt cgtcagttct
    21481 atctacaacc tcaaagcagt gctttgagca acccgcggct agcttcctag tttgctcttt
    21541 gattttcatt gagtataaat aaaaaaacag aactagtctg aactagtcct gtctactttt
    21601 acccaatcac acttccattt ggtacagctg gatcaactgt gagaagggtt aatttgccat
    21661 catgttcagc tgagagaatc ataccctggc tgacatattt tttcatcatt ttacgtggtt
    21721 tgaggttagc aacgatttga actttcttgc cgaccaattc ttgttcattt ggatagtatt
    21781 ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc agcatccaag cggaattgaa
    21841 gcaacttatc tgaaccttct actttagaca cttctttgac ttctgcgaca cggatttcaa
    21901 ccttgtcaaa gtcttcaaac ttgatttcat ccttgtttag tttgagctca acttcgtccg
    21961 gattccattc tttttcgact gctggtttat tgccttccat ttgttccttg atataggcga
    22021 tttcttcttc catatttaga cgtggaaaga taggtgttcc tttggcaact acagtcacat
    22081 ctgctgggaa gtcagccaaa ctcaagtttt caagactaga aacttcttcc aaaccaagtt
    22141 gagtcaaaac tgcacgacta gtttccatca taaatggttc aatcaagtga gcaactacac
    22201 gaatgctggc tgccaagtgg ctcatgacac ttgccaattg gtcacgaaga gcttcatcct
    22261 tggccaagac ccatggtgcg gtctcatcga tgtatttatt ggtacgagag atcagagtcc
    22321 agactgcttc aagcgcacgt ggatagtcaa ctgcttccat gtgtgtatgg aagtctgcga
    22381 ttgattgttc tgcaacctca gcaagaacat gatcaaattc agtcacacct tctacatagg
    22441 cagggatttg tccatcaaag tacttattaa tcatggaaac cgtacggtta aggaggttcc
    22501 caaggtcatt agccaattca tagttgatac ggccgacata gtcttcagga gtaaaggttc
    22561 cgtctgaacc aactggaagg ttacgcatga ggtagtaacg aagtggatct agtccataac
    22621 gctctaccaa catttcaggg taaacgacat tcccttttga cttagacatt tttccgtctt
    22681 tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa tttaacatcc aacatcataa
    22741 gaaggattgg ccagtagata gagtggaagc gaaggatatc ttttcctacc atatggaaga
    22801 ctgttccatt ccagaacttg tcaaagttac catgttcgtc ttgagcgtag ccaagagcta
    22861 tcgcatagtt aagaagggca tcaatccaaa cgtagacaac gtgttttgga tttgatggga
    22921 caggcactcc ccatgtaaag gttgtacgag ataccgccaa atcttccaag cctggctcga
    22981 tgaagttgcg tagcatttca ttaaggcgac catctggcgt gataaattca ggatgagctt
    23041 tgaaaaattc gaccaaacgg tcttggtatt tgctaaggcg aaggaagtat gattcttcag
    23101 aaacccattc aacctcatga cctgatggag caataccacc agtcacattt ccagcttcat
    23161 cacggaaaac ttctgccagc tggctttctg taaagaattc ttcgtctgat actgaatacc
    23221 aaccagagta ttcacccaag tagatatcat cttgagcaag taagcgttca aagacttgtg
    23281 cgacaacttt ttcatggtag tcatcagttg tacggataaa tttatcgtat gagatatcta
    23341 gtaattgcca gagttcttta actccaaccg ccattccatc aacataggct tgaggtgtaa
    23401 taccagcttc ttccgctttc tgctggattt tctgaccatg ttcatcaaga cctgtcagat
    23461 aaaatacatc gtagcccatc aggcgtttgt aacgtgctag gacatcacat gcgatagttg
    23521 tgtaggcaga accgatatga agtttcccag atggatagta aatcggcgtt gtaatataaa
    23581 aatttttttc agacataatt tttcctttcc aggcaaatga aacctgtttt tctaacactt
    23641 cattatatca catttttaat gaatttcaat agggaaatcc atacaaaaac aagatagacg
    23701 agtgtccatc ttgttgatct cattcataac gaagggcttc aattggatca agtttcgatg
    23761 ccttgttggc tggcaagact ccaaaaatca taccaacact agccgaaact gcaagactaa
    23821 atagggcgac tgggattgat actccaactt ctataccttc tattaaacct tgcagtaaca
    23881 aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc aattaagcca cctaacaagg
    23941 tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt ggcacgtgtt gcacccaaag
    24001 ccttacgaag accaatctca cgagtgcgct ctgtcaccga aaccagcatg atgttcatga
    24061 caccagttcc tccaacaaag agagaaatcc ctgcgatgga actaataatc gtcgtcataa
    24121 aactaaacga ttgttgaatt tctgcaaata caagggactc atctgccacc tggtattctc
    24181 cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag ttctggaccc agagttgggg
    24241 ttaaactggt atcattcact cgaaagacaa tactagctat ttcatctaca ttaaaattcg
    24301 cagcaaggga gatattggta gtaataggca agccaccaaa cccatatatt tttgatcttt
    24361 tagcctccgg actagtataa accccaatga cccggtaact aaatccattg acttctacaa
    24421 ccttgttaat agcctcttga ggagattcaa ataaactaat ggacaattcc tcatctagca
    24481 aaataacact tgcaaactct ttgaaatctt gctctctcag actacgacct gcaataattt
    24541 cattcttaac agcgtccatg taagttctgt ttccacctgt caaattagca ttctcaacct
    24601 ttttatcttg ataggtcaag atggcattcg ttgaattggt tacatagtaa ctatccactc
    24661 ccttcagttt agctgcctct tggacccagg attcttgcgg ttttggcggt tcaacaggaa
    24721 cttcctcttc ctttccagaa accgtaaaag ctgattgttt ctgagtaaaa gacccatctt
    24781 tacttttttt aggagagaaa aagacgctaa tatttttctg agatttagtc atatctttat
    24841 tgacttgacg agatagggaa tcacccaaag ccataatcac aacaactgat gaaacaccga
    24901 taataatccc aatcatagta agcaaagaac gcatcttgtg agccatgata gatgaaaagg
    24961 caaatttcag attctgcatc ttagttttcc tcctttccta actgagcact gtcagacgaa
    25021 atgaccccat cccgaatgac aatctgacgt ttggcatagg cagcaatctc aggctcatgc
    25081 gttaccatga taatggtttt tccttcttta ttcaaatcaa ccaataattg cataatttgg
    25141 ttacctgttt tggtatccaa ggctcctgtc ggttcatccg ctaggataat agaaggattg
    25201 tttaccaagg cacgcgcaat ggctacacgt tgcttttgac caccagataa ttctgaaggt
    25261 aaatggtgac tacgttctgt caattcaacc ttgtctaaat attcctcagc caacttgcga
    25321 cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt ctacattttg cagagcattg
    25381 agcttcgata gaagaaagaa ctgctgaaag acaaaaccga tttgttggtt acggacctta
    25441 gccagttgtt tttcaccaag cccagccact tcttgacctt caagataata ttctccactg
    25501 gttggtgtat ccaacatgcc aatcgtattc atcagagtgg acttaccaga cccagatggt
    25561 cccatgatgg ctacaaattc accctcattc acttctagat tgatattttt gagaacctgc
    25621 aattcttggt caccattacg gtagcttctg aagatatttt ttagactaat tagttgcttc
    25681 atcagtcttc acctcttttc cttcttccaa ggaagatgtt ggattactga tgaccttagc
    25741 accattcgtt aaaccagaag tgatttcttg attttctgcg tcagcatttc ccaatgaaac
    25801 ctcaactttt ttagcctttt gttgttcatc cacaatccag acataatttt tactatcatc
    25861 cattactaga ctgctaacag gaacaagaat agccttagtt ttgcttttaa cctcaatgtt
    25921 gacagaaaaa ccctgtttca aatcaccaac ctcgcctgtc acatcaatag tataagggta
    25981 tttagaacct gtattatttc cggctgctgg actagctgct tcaccattgt ttttaggata
    26041 gtcagaaata tagcttaatt tcccagtcca ttttttatca ggatacactt tagaagtaaa
    26101 gcttacttct tgacctacag aaaggttggc tagattgtac tcagacaatt ctcccttgac
    26161 ttgtaaattt tcattgctga caatatgaac cataacttgg ctcgcccctg ttggagattt
    26221 agaaacattg ctattgactt cgactacagt tccctctagg gtactgagaa cagttgttgc
    26281 atccaattga ctttgagcct tgcttaattg cgccgcagca tctgcacgcg catcacgggc
    26341 atcacccaat tgagcgtcaa tagaagcaac agaatttcca gccactggag ttgggctttg
    26401 caccgttgca tcttctcctc ctactggcgc tggtaactgt ggagccggag ctgaagcggc
    26461 ttcatttcgt gcttgattga gttcattgat atgacgatct gccttagcta ctgctcgact
    26521 agctgaatca taggccgcct gcgcttctga actactgtac ttgactaaag cctgcccttc
    26581 gctgacctta tcgcccacag aaacaaggat ttcatctaaa tcacccttac tagcatcaaa
    26641 ataaacatat tgttcatttt ttgctgttac tgtccctgac aataaaacag aggatgccac
    26701 gcttccttcc ttggcaacaa caagatgagt aggctcatct tttagagcag tctgagaagg
    26761 ttgtctaaag agtaaaatcc ccccggcacc caatacaact acactcgcag caccgattgc
    26821 tgcatacagt tgccactttt tagctttacc attctttttc ttcataatga aactcctttt
    26881 cttttttaca atactttgct attataccaa atttccctcc agcaaacaat gcagttcaga
    26941 tggaaataat ggcagttcag gattaaacaa tcgttcggaa ttttactttt ctattgtact
    27001 agatatataa tacactatct taacttattt ggcaagcttt tttgcaattt tttgtgcgta
    27061 gcagattttt gcaatcaaat caaaaaaaga ataaaatata actatcaaaa aagacgctct
    27121 actatttaaa agattacaaa ggagttttca atgagagaat atgatatcat tgctatcggt
    27181 ggaggtagcg gaggaatcgc taccatgaac cgtgctggtg aacatggagc caaagcagcc
    27241 gttattgagg aaaagaaatt aggtggaacc tgtgtcaacg tcggttgtgt tcctaaaaaa
    27301 atcatgtggt acggggcgca aatcgctgag actttccatc aatttggaga agactacggc
    27361 tttaagacta ctgatcttaa ctttgacttt gcaaccctac gtcgcaatcg tgaagcttac
    27421 attgatcgcg ctcgttcttc ttatgatggt agttttaaac gcaacggtgt agacttgatt
    27481 gaaggtcatg ctgaatttgt agattctcat actgtaagcg taaatggtga actgattcgt
    27541 gctaaacata tcgtgattgc tacaggtgcc catccaagta ttcctaatat tcctggtgct
    27601 gagctaggtg gctcttctga tgatgtattt gcctgggaag aacttccaga gtcagttgcc
    27661 attctaggtg ctggttatat cgccgttgaa ttagctggcg tactccacac ttttggtgtc
    27721 aagacagatc tctttgttcg ccgcgatcgt cctttacgtg gttttgattc ctacatcgtt
    27781 gaaggtttgg tcaaggaaat ggaaagaata aacttgccac ttcatactca caaagtccct
    27841 gccaagttag aaaaaactgc taaaggcatt accattcatt tcgaggatgg taccagtcac
    27901 acagctagcc aagttatctg ggctacaggt cgccgtccaa acgttaagag cttgcaactt
    27961 gaaaaagctg gagtgactct gaatgaacgt ggctttatcc aagtagatga ataccaaaat
    28021 actgttgttg agggaatcta tgctctaggt gatgtaacag gtgaaaaaga actgactcca
    28081 gttgcaatca aggccggacg taccctatct gaacgtctct ttaacggaaa aactactgca
    28141 aaaatggatt actcaactat tccaactgtt gtcttttcac accctgctat cggaactgtt
    28201 ggtttgacag aagagcaagc tattaaagaa tacggtcaag accaaatcaa ggtttataaa
    28261 tcaagctttg catctatgta ctctgcttgc actcgcaacc gtcaagaatc ccgtttcaaa
    28321 ctcataacag ctggttcaga agaaaaagtt gtcggacttc atggaattgg ctacggcgtt
    28381 gatgaaatga ttcagggatt tgccgttgct atcaaaatgg gagcaaccaa ggctgacttt
    28441 gatgcaactg tggcaattca cccaactgca tctgaagaat ttgtaaccat gcgttaatcg
    28501 aaacaaaaga agctgatata aatatgtctg cttctttttt aatgattttc gaatcaacaa
    28561 aaaaattatc caacttgact agtcacgaaa atcggctgtt acagtttttg ttaccttgtt
    28621 tttaaaaaat ggttgacatc gactcctata tgagtataat agttactata cattagaaaa
    28681 gaggttaact attttgaaaa aagctcacgt ttatgctatc cctgctattg gggctgctct
    28741 cattgctgct ttggcacaaa tcagtcttcc aattggacct gttcccttca ctctgcaaaa
    28801 ctttgcaatc ggcttgattg ctactgtctt tagaccgaga gaggctgtac tttctgctgg
    28861 actctatctt cttctaggtg ctatcggtct tcctgtcttt gcaggaggtg gagctggttt
    28921 tcaggcttta gttggcccta ctgcaggcta tctttggttt tatctcgttt actctggact
    28981 tacttcctct ctaaccaaca gcaagagtgg tgttgttaag atttttcttg caaacctctt
    29041 gggtgatgcc cttgtctttg tcggcgggat tctcagcttg catttcctag ctggaatggc
    29101 atttgaaaaa gctcttgctg tgggggttct tccctttatc attccagacc ttggcaaact
    29161 tctggctatt agttttatta gccgtcccct acttcaacgc cttaaaaatc aggcttactt
    29221 tactaactaa aaaaggatat cgagttatca tgactcaata tccttttctt ttattttgaa
    29281 aacttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgctcaaaa
    29341 cactgttttg aggttgtgga tgaaactgac gaagtcagta accatacata cggcaaggca
    29401 aagctgacgc ggtttgaaga gattttcgaa gagtattagt tgcctttaaa ggcatccacc
    29461 atcgtttgaa attcttcatt tgagagagta atccctttgc ccattttagt atggtctgga
    29521 ctccaagcac gaatatcaaa ctttgcaggg gcaccattaa agctcacacg gttaatttcc
    29581 ttggtccaac ctttttcgtt ttcagaaaga gtcaacaagt gctcttcgat ttcaaatgta
    29641 aattctgcca ttttcttctc cttttttagt ttcattagtt tattcgtaaa atcttgtaga
    29701 ttttaggaaa attttatata atattgatat aaaagaaggg aggccaatat gagacataaa
    29761 ttccagcaag ttctaaataa aatacatgat tttttaaatg gatatgacca acctgaccag
    29821 actgaaacca actcccttac agccactatt gaagaggcta tccagaaaca aaccgctgtt
    29881 caccttatct tatctgagac aagctttaca ggtgacatca tcaaatatga tcagcaaggc
    29941 cagcaaatta tcgtgaaaaa tttttccaaa aatgtgagcc ggattatccg tataagcgat
    30001 attcaacgcc tgcgatttgt cccctcaact gtccaaacag cccaaaaaaa tagatttaag
    30061 aaagagtgag atgtagttgc ttcatcccac tctttttctt agcgaatttg ttcaaaatgt
    30121 aaatgaactg cgatatgatc tccataacca cttctttcca agtcacgttg taaacgatag
    30181 gaaatatagt gttctgcaat ggtaatgtaa cctgcgccca ataaacgatg ttcaaccata
    30241 gattgaatca tactgatagt cgcacgttcc accttggctt cttgtaaatc caaaactacc
    30301 ttcttagtga cttgagcaag attttgacgc aaatcatctg tcaaaacata aacagtttgg
    30361 gctgccttca agatggcttg gtaaatctta tctggattaa attcagcaat ttcgccatta
    30421 cgtttgatta cttgcatagg tttctccttt attctttgtt ttctttgatt tctgccagca
    30481 ttttttcttc ttctactgtc agttgataat gttcaagtaa atccggtctg cgctcgtagg
    30541 ttttctttaa actctcgtac aatcgccact gacgaatctt ttcatgatgg ccactcatca
    30601 atacatctgg cacgaccatg cctcgataat catagggacg tgtgtactga ggatattcta
    30661 aaagacctga agaaaaacta tcatcttggt ggctagactc cttgccaatc acttctggaa
    30721 tcaggcgaac tgtagcatca atcatggtca tagctgccaa ttctccacca gtgaggacat
    30781 agtcacctag ggaaatctca tctgttacca aggtcttaat gcgctcatca taaccctcat
    30841 agtgcccaca gataaagatt agctcttcct cttgagccaa atcttcagca taagcctgat
    30901 caaactgctt tccagcagga tcaaggagaa taacgcgcgg atttttcttt tcaatagcat
    30961 caaaggaatc gaaaataggt tgtgctctga gcaacatgcc ctgaccgcct ccgtagggct
    31021 catcatctac atgacgggcc ttttcagcat tttctcgaaa attatgatac tggatatcca
    31081 agagcccttt ttctcgagcc tttccaacga ttgagtgctc cagtggagaa aacatctctg
    31141 gaaagagggt taaaatatca atcttcatcg tctaaccctt ctaagatttc cacatcgacc
    31201 cgtttatttg gaatatcaac attgagaacc actggtggga tataaggtaa aagcaaatca
    31261 cgtttgcctt ttcgtttgac cacccagaca tcattagcac ctggttgcag gatttccttg
    31321 atggttccaa ccaagctatc accctcatag acttccaaac cgataatctc gtgatagtaa
    31381 aattcaccat cgtctaggtc attcaaatct tcctcagcga ccttgagact gtatcccttg
    31441 tacttttcga tagtattgat atggtacata tctttgaatt taataatgtc aaagttcttc
    31501 tgtttacggt ggctagcgat ggtcactgtt tggacaaact gatctttttc atcaaacaaa
    31561 gccagctcag ctcctttttt aaaccgttct tctgcaaaat ccgtcacaga caagactcgc
    31621 atctcaccct gtaatccctg cgtattaacg attttcccaa cattaaagta gttcatcttg
    31681 tctcctgtaa tctccttttt tccatcttat tctgacaatt ctcgaataat agccgcaatt
    31741 ttttccgatt ctgaccattg taaataatgg tgattccctc ctaaaatgag tttagtattg
    31801 gaagtccaat attctgattc tctgtactct ttttctctat aagtctgaca aaaaataaat
    31861 acagggacat gagattctat cgacaaattc tcaaaatctt cctcagtaat ctctccagat
    31921 atctgaaatt ctggatcttg attttccaac tctaagcctt tttcttgcat taattcccag
    31981 atttttttat tcgtttcagg actaaatgtt gcttgagtta agttcttaaa ataaagttca
    32041 ggaccacact cgtcaatcag cctcatctgc tcttccattt ctggataagg attttctgaa
    32101 aaatcagcaa acatgacttt tttagttgtc ggttcaattg ctactaaagt ctgacactta
    32161 attggtttct cgagtaattt gcaagctaaa attccactcc aactatgtac acaaagtata
    32221 tattcagaaa tccctaattc ttcaagtgct tcataaacca catctgcaag attatctaga
    32281 ttttttccag cttggtcatg aatcggactc ctacctgtgt tcggaaaatc aattgtcaaa
    32341 taaccaattg taggaggagg tttttcaagt ataagtgaaa aattttcata acttggtagc
    32401 aaacctgctc cgtttagaca aactagcact ttcttttgct tttgataagc aacagagaga
    32461 ctaccaattt ctgtagatac ttcaaacctc ttcataaaga aatccactga ttctatataa
    32521 tgaattatta aaaatcctta tcctttattt tatcacgttc caaggatttt ctcaagttgg
    32581 aggaagggga caatatctct actttccctt caataatcct tccaaattat gtttatgttg
    32641 gtaattaacg gctgcggttt tgtctttctc aaagacagtc ttggtaaggt caatatgatt
    32701 aatagctacg attgcgacgg tgtagtaaat gatatcagcc agttctctgg caagttcctc
    32761 gttcgaatcc tatcccttct tttcgaccag agcgcctatt caaaacctcg gctacttctc
    32821 cgacttcctc cactaacttc ataaagagac cttcatcagt ccgagactgc tgttaatgtt
    32881 cgattaagta gttttggaat tgcctaaacg ttcaatcttt tatagtatat tgaaactaga
    32941 atagtacacc tttacttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt
    33001 gtcctgttct tgtttcattt tactatatct tctattccac acaaaaaagc gagacatccg
    33061 tcccgccctt cttatttttc gtcaataacg attcttactt ttttgtattc agttgggaca
    33121 gagtagacaa tcgttcttat cgcagaaata gtgcgaccct tacgaccgat tacacgaccc
    33181 acatcgcttt gatcaagatt caaatgatat tccaaaaatt ctggtgtatc ctcaatcttg
    33241 atagttaagg catctggttg tgaaattaag ggtttcacaa tcgcaataat gagattttca
    33301 atcgtatcca tctgtcaacc tactttaaac ttattttgaa aatttagaat cgtggaattt
    33361 tttcaatacg ccttcttttg aaaggatgtt acgtactgtg tctgaaggtt gagctccatt
    33421 agccaaccat gcaagaacgc ggtcttcttt caaagttact tggttttcag caacaagtgg
    33481 gttgtaagtt ccaactgttt cgatgaaacg tccgtcacgt ggtgaacgtg aatctgctac
    33541 gttgatacgg tagaaaggtt ttttcttaga acccatacga gtcaaacgga ttttaactgc
    33601 catttttaaa gtctcatttc tttaattttt tatttcggtg aaatagctga gctatttagc
    33661 acatgttcta ttatagcaga tttctggcat gtgtcaagaa aaaaacttga cagactataa
    33721 atttcttaaa gtatttagaa atttgttaga ataggaaata aatgtttgaa aga
//
LOCUS       DAVLUM010000021        33305 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLUM010000021 DAVLUM010000000
VERSION     DAVLUM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33305
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.021"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            220..516
                     /locus_tag="VYN42_000805"
     CDS             220..516
                     /locus_tag="VYN42_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1461906.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIYSNGASIG"
     gene            637..1581
                     /gene="manA"
                     /locus_tag="VYN42_000806"
     CDS             637..1581
                     /gene="manA"
                     /locus_tag="VYN42_000806"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1461907.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1602..2881)
                     /locus_tag="VYN42_000807"
                     /pseudo
     CDS             complement(1602..2881)
                     /locus_tag="VYN42_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(2878..3099)
                     /locus_tag="VYN42_000808"
     CDS             complement(2878..3099)
                     /locus_tag="VYN42_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1461908.1"
                     /translation="MIFLTDLRKHDRIVKSINQTESYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGWPSGLVPFGSFPT"
     gene            3204..3944
                     /locus_tag="VYN42_000809"
     CDS             3204..3944
                     /locus_tag="VYN42_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1461909.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAVYVQTNAE"
     gene            complement(3973..4428)
                     /locus_tag="VYN42_000810"
     CDS             complement(3973..4428)
                     /locus_tag="VYN42_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1461910.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4448..5623)
                     /locus_tag="VYN42_000811"
     CDS             complement(4448..5623)
                     /locus_tag="VYN42_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1461911.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5682..6527)
                     /locus_tag="VYN42_000812"
     CDS             complement(5682..6527)
                     /locus_tag="VYN42_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1461912.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6652..7209
                     /locus_tag="VYN42_000813"
     CDS             6652..7209
                     /locus_tag="VYN42_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1461913.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFRETRKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7228..7695
                     /locus_tag="VYN42_000814"
     CDS             7228..7695
                     /locus_tag="VYN42_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1461914.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7784..8413
                     /gene="upp"
                     /locus_tag="VYN42_000815"
     CDS             7784..8413
                     /gene="upp"
                     /locus_tag="VYN42_000815"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1461915.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8587..9177
                     /gene="clpP"
                     /locus_tag="VYN42_000816"
     CDS             8587..9177
                     /gene="clpP"
                     /locus_tag="VYN42_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1461916.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9256..9504
                     /locus_tag="VYN42_000817"
     CDS             9256..9504
                     /locus_tag="VYN42_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1461917.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9605..10765
                     /locus_tag="VYN42_000818"
     CDS             9605..10765
                     /locus_tag="VYN42_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1461918.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11033..11902
                     /locus_tag="VYN42_000819"
     CDS             11033..11902
                     /locus_tag="VYN42_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1461919.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11906..12862
                     /locus_tag="VYN42_000820"
     CDS             11906..12862
                     /locus_tag="VYN42_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1461920.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGTLLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12862..13626
                     /locus_tag="VYN42_000821"
     CDS             12862..13626
                     /locus_tag="VYN42_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461921.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13626..14336
                     /locus_tag="VYN42_000822"
     CDS             13626..14336
                     /locus_tag="VYN42_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1461922.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14644..15300
                     /locus_tag="VYN42_000823"
     CDS             14644..15300
                     /locus_tag="VYN42_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1461923.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15408..16503
                     /gene="prfB"
                     /locus_tag="VYN42_000824"
     CDS             join(15408..15479,15481..16503)
                     /gene="prfB"
                     /locus_tag="VYN42_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1461924.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16521..17213
                     /gene="ftsE"
                     /locus_tag="VYN42_000825"
     CDS             16521..17213
                     /gene="ftsE"
                     /locus_tag="VYN42_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1461925.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17206..18132
                     /locus_tag="VYN42_000826"
     CDS             17206..18132
                     /locus_tag="VYN42_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1461926.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18418..20598
                     /locus_tag="VYN42_000827"
     CDS             18418..20598
                     /locus_tag="VYN42_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1461927.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20650..21465
                     /locus_tag="VYN42_000828"
     CDS             20650..21465
                     /locus_tag="VYN42_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1461928.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSLQVSDHYGLNAILNWK"
     gene            21605..22948
                     /locus_tag="VYN42_000829"
     CDS             21605..22948
                     /locus_tag="VYN42_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1461929.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23163..24353
                     /locus_tag="VYN42_000830"
     CDS             23163..24353
                     /locus_tag="VYN42_000830"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1461930.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24906..25841
                     /locus_tag="VYN42_000831"
     CDS             24906..25841
                     /locus_tag="VYN42_000831"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1461931.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25875..26912
                     /locus_tag="VYN42_000832"
     CDS             25875..26912
                     /locus_tag="VYN42_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1461932.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27085..27690
                     /locus_tag="VYN42_000833"
     CDS             27085..27690
                     /locus_tag="VYN42_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1461933.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27846..28376
                     /locus_tag="VYN42_000834"
     CDS             27846..28376
                     /locus_tag="VYN42_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1461934.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            28397..29482
                     /gene="rlmN"
                     /locus_tag="VYN42_000835"
                     /pseudo
     CDS             28397..29482
                     /gene="rlmN"
                     /locus_tag="VYN42_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
     gene            29482..29964
                     /locus_tag="VYN42_000836"
     CDS             29482..29964
                     /locus_tag="VYN42_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1461935.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29966..31507
                     /locus_tag="VYN42_000837"
     CDS             29966..31507
                     /locus_tag="VYN42_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1461936.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31563..32366)
                     /locus_tag="VYN42_000838"
     CDS             complement(31563..32366)
                     /locus_tag="VYN42_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1461937.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32449..32661)
                     /locus_tag="VYN42_000839"
     CDS             complement(32449..32661)
                     /locus_tag="VYN42_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461938.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
BASE COUNT        10085 a         6224 c         7275 g         9721 t
ORIGIN      
        1 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttgt ttcattttac
       61 tatagaacga tttgaaggcg tttataatat ttagctgtac gagagtcttt taaaagtgtt
      121 ttgatggttt ggatttcttc tttagttgat ttcatatcac tattatataa tgttttttga
      181 ttttagttta gtattatcgt agaaaatgga ctcggtgcta tggatacacc ggatgagaat
      241 ggttatgtag cagatgacta tcggattact tacttagagg cccacatcaa ggccatgcga
      301 gatgccattt accaagacgg ggttgacttg cttggttata cgacttgggg ctgtatcgat
      361 ccggtttcag ctggcacagg ggaaatgaat aagcgctatg gctttatcta tgtagatcga
      421 gataatgtag gaaacggagc tctcaaacgt agcaagaaga agtccttcta ttggtacaag
      481 gatgtcattt atagcaatgg tgcaagcatc gggtagagca catttgttta ctatttttat
      541 aaaatcttct ccctgcttta taagatgtaa aaaagagttc aattcgaact ctttttttgc
      601 tataatgagg ggagaaaaat cagacaggag atcgacatgt cagaaccatt atttttacaa
      661 tcagttatgc aagaaaaaat ctggggtgga gccaagctac gtgatgagtt tggctacgac
      721 atcccaagtg aaaaaatcgg agaatattgg gccatctcag cccatccaaa tggagtctct
      781 aaagttgcca atggtcgtta cgagggaaca gatcttgcta ctttgtatgc ggaacaccgt
      841 gaattatttg gcaatcgtcc agaacctgta tttccacttt tgaccaagat cctcgatgcc
      901 aacgactggc tcagtgtcca agttcaccca gacgatgctt atggactcga gcatgaaggc
      961 gaactcggaa aaacagaatg ctggtacatt atcgcagcgg atgaaggttc agagattatc
     1021 tacggtcaca atgccaagtc aaaagaagaa ctccgccagc aaatcgagga caagaactgg
     1081 gatgacttgt tgaccaaagt ccctgttaag gctggagatt tcttctatgt accaagcggg
     1141 actatgcacg ctatcggggc gggtatctta atccttgaaa cccagcagtc tagcgatacc
     1201 acctatcgcg tctatgactt tgaccgcaag gatgacaaag gcaacttgcg tgaacttcat
     1261 cttgaaaaat ccatcgatgt cttgaacatt ggtgagccag caaatagccg tcctgtaact
     1321 gttaaagcag atgatttgcg ttccactctc cttgtatcta atgatttctt cgcagtttac
     1381 aagtgggaaa ttactggaaa agttgacttt gaaaagacag ctgactacag cttattgagt
     1441 gtcttggctg gtcaaggtca gctaactgtt gacgggaaaa attatccaat tcaaaaaggc
     1501 agccacttta tcctaccaag tgatgttgaa gcttggactc tggaagggca aggtttggaa
     1561 ttgattgtta gccatccata aaaagaaagg gcctgagttc actactcaag tcctttttga
     1621 ttacataaat tgggcaatga agaccacaat gatgatgatt ggaatgacga aacgaagaaa
     1681 cgaagaaacg aagaaggaag agccagactt ggaacagtcc ttgtttccat gctctttcat
     1741 cgagatggag ttcctccatt gcaagagcct ttttaaagat atagcctgta aaaagtgaaa
     1801 ggtagagagc tccaaatggc atgaggagat tggaaaccaa gaagtccata gcgtcaaaga
     1861 aggtcttacc aaaaatgtga acatccgcca tgacaccgta agatagggct gaaggaatac
     1921 caaagacaaa ggtcaaaatt cctaaaataa cactccattt ggcacgtttg ctgttatcct
     1981 ggttggtgat attgtctaca ttgatttcca gcatcacgac agaaaaagtg actgtcgcaa
     2041 aaaggaagag caagaggaag aggacgtaga aaatggttcc aaaaggcatc ttgtcaaaga
     2101 gttgaggcaa gacgataaag agcaggctgg gtcccccttc agactggata ttgaaggggg
     2161 atcgagcttg gaaaatggct agacctgcca tgatggatat cgagatattc atggctacga
     2221 tggagattcc tgactggact agattggttt tcttgtctaa gtaagaagca taggtcaaca
     2281 tgactgtaac ccctagtgag agggcaaaga aagattgtcc cagagcatag aggagaccag
     2341 tgctagtcag ttttgaaaag tctggtttga ggaagtaaag aaccccttcc atggcatttg
     2401 gcaaactgag agagcgaccg atgataaaaa caaagacgat aaagagcagg ggcatcatga
     2461 ctttcgaagc tctttcaatc cctttttgaa ccccacgtga tacaatgaag atattcaata
     2521 ggataaaggc cgcttgagct cctagggcaa tggctggatt tgaaatgatt gaagtaaata
     2581 actgagcata atcacccgtt ccaccaagtt ggaacaattt cccaaactca atacctagat
     2641 agactagaat ccatcctccg ataacactgt aaaaagataa gaggataaag agggcaaagg
     2701 cgccaatcca accgataaag ttgtacttgt tattcttgcc cagttttcca aaggttttga
     2761 tatcggaaac gccagcacta cggccaaggg caaactcagc cagcaggaga gggaaaccga
     2821 ttaaaatagt ggaaatgaga aagattagta aaaagcctcc accgccatta gcagcagtca
     2881 tgtagggaaa cttccaaacg gaaccaagcc cgatggccag ccagcagatg ctagaataaa
     2941 accaagtttc gacccccatt gtgatttttc tgacatagtt aaactctgat ctcctttttc
     3001 aaaataagaa aaagctactt gagttgtcaa atagctttct gtttgattga tagacttgac
     3061 tatcctatca tgttttctaa ggtctgtcaa gaaaatcatt ttcaagtttt cacacctttc
     3121 tcaaaaaagt taaaaaattt tctcaaaaac gcttgactct gacctaaggg gaggggttat
     3181 actatcattg taaggaggaa atcatgtacc atataaaaga agctgcgcag ctttcaggtg
     3241 tctctgtcaa gaccctgcat cactatgaca agataggact cttggtcccc ttaaagtcgg
     3301 aaaacggcta tcgaacctac agtcaagagg atttggaacg ccttcaggtc attctttact
     3361 acaaatatct aggcttttct ttagagaaaa tagcagagct gttaaaggaa gaaaggacag
     3421 atttattgcc ccatttgact aggcagttgg actatctaac tcgcgaaagg caacatctgg
     3481 ataccttgat ttccaccttg caaaaaacta ttcaagaaca aaaaggagaa agaaaaatga
     3541 ccattgagga aaaattcacg ggatttagct atcaagacaa tcaaaaatac caccaagaag
     3601 cggtagagaa atatggtcaa gaagtcatgg gacaagcgct cgaacgccaa aaaggtcacg
     3661 aagacgaggc tacggccgcc tttaaccaag tctttcaaac tttggcacaa aatcttcaag
     3721 ttggtttacc tgcaacagca accgaaaacc aggagcaagc agccaagctc ttgcaagcca
     3781 ttcgcactta tggatttgac tgctctattg aggtattcgg tcatatcggt aaaggttacg
     3841 tctacaaccc agagtttaag gaaaacattg acaagtttgg ttctgaaaca gcccagtaca
     3901 cgtcagatgc cattgcggtt tacgttcaga caaatgcaga ataaataggc taggaatttc
     3961 ctagcctatt ttttacttca aatcataaag ccagtcgtca ccgtttttgt agtaaaagaa
     4021 ttcactgaga tcttcttcta gaaacacacg aagcatatca gacatatcat cggttgcaag
     4081 ttttagatga gaaagatttt caaagtcctc ccaccaaact ttcccttcgt ctgaagactg
     4141 gagttcacca gtaaagtgtt ctgtcttgta aaaaaggacg acataacgat aatccttgtc
     4201 gtcataccag tttttgatac cacagagttg gggtttggaa atgatcagac cagtttcttc
     4261 tttcacttca cgaatgacag catcgacaaa ggattcgcca cgttcaacat gaccaccagg
     4321 aaaagtaatg ccagaccagt cgggactaac tcggtcttgg accaggacct tatctccgtt
     4381 tttaatcata cacatgttaa caaattcgac tgcctctctt ctgttcattc ttcacaacct
     4441 ttaatcttta atcataatgc agacttcccg ccacccagcc ggtacagagg gcagaagtga
     4501 tgttaaagcc acccgtgtgg gcattgatat ccataacttc gcctgcaaag tggaggccag
     4561 gtaccagctt actttcaagg gttttaggat tgatttcctt gagactgact ccacccttgg
     4621 taacaaagga ctttgcaagg gacatttttc cagttacagg aattttaagt tctttaatgg
     4681 actggacaag ttgttctcgt tccttttcag tcagttgttt gactttttca ggatatcctt
     4741 gtacaaaaaa ttcggccaag cgttctggta acaaggtttt taaagcgttt ttcaaggatt
     4801 tttcccgatt ttcttctaga aatgtaacca agtccttctc agaaagttga ggcaaaacat
     4861 cgagtgagag aacctcccca cctttgacaa agctagacat gcgtagggca gcaggacctg
     4921 acaaaccaaa gtgggtaaag agtaaatcat gagtgatgac atgcttacca taacttaggg
     4981 tcacatcgtc cagagaaata ccttgtaagg ctttatgtgg aaaatctgtt aataaaggac
     5041 tttcagcagc ctcaagatcg gtgatggtat gcttaaaatg gcgagcaatc tcgtgaccaa
     5101 aaccagtcga accagtcgaa ggataagact taccacctgt tgtgacaatg agtttctcac
     5161 aagtgaaggt ttgatccgct gacttaagga caaactggtc atctactttt ttaacagaaa
     5221 cgatttctat ttgagtagca acttgaccac ctagttcggt gattttcttt tccaaagctt
     5281 cgataatagt ccgagacttg tcactggctg gaaagacgcg tccgtggtct tcgaccttaa
     5341 gtttaacacc attttctgta aaaaagttga tgatgtcatg attatcgaac tgggagaaaa
     5401 cactgtaaag aaagcgtccg tttccaggaa ttccagctag caggttgtct aagctaccat
     5461 tgttggtcac attgcaacgt cccccaccag tcccagctaa tttttttcca agtttccgat
     5521 ttttttcgat gaggagggtt ttctgtccat aaaagctact ggaaatcgta gccatcatac
     5581 cagcaggtcc cccaccgatg acaatagtat caaaatgttt catagctcta ttgtaccaca
     5641 aaaaaacaag agatgatggt cacctcttgt caagaatgca attaatcaat ttcatagccc
     5701 atcagcaaac cgccctcttc tgcatagaaa ctgcagagac cagaggttgg tagaatttta
     5761 atatccgctt gtgggaaggt ttcacggatt cgctctgaga gctgttgaca acatttttcg
     5821 ttattgcgtt gggccatgac aatacggcca ccagcatatc cagcttttac taattcatca
     5881 taggcagctt gaactgattt ctttgatccc cttgcttttt gtagcaattc gagagtccca
     5941 gtttcactag cttttccgac catacgaatg ttgagaaggc caacgaccgt accgataagc
     6001 ttgctcaaac ggccgttctt caccaagtta tcgactttgg ctaggacaaa gagcaactta
     6061 gttttttctt gataggcggt gatagcttca accacttctt caaaagacaa gccctggtca
     6121 atcaagtcat tcaatttttc tacgagtagg tcaacttcac caccagcaga taaactatca
     6181 atcacatgaa tcttagtgtc aggatggtct tccagataaa tattctttgc tagttgagca
     6241 ctattgtgac tgccagaaag ggtacctgtg atggttacta ggaaaatgtt tttggcacct
     6301 tcaaatgctc gcaaatagtc atctgggctt ggacaagctg attttgaagc ttctgcagtt
     6361 gcatacatgg tttccatcat ttggtcaata tcgagactgg cgtcatcaac aaagacctga
     6421 tcagctactt gaatggttaa ggggacactt acaaaggttg tgttaatagc tggtgttggc
     6481 agttgacgat aatcacaacc agagtcagca ataatcttcc aagtcataga aattctccat
     6541 ctttgtcagt tatacattga caaaggttct gtcttttttt acaattatat catgaaaact
     6601 cttgaaacaa aagcatcatc cgtctgttgt gacaagtaga aagaaaatgt tatgtctgaa
     6661 cgtagaatct ctgaaaagtc tcttgaaaat ctcagaaaat caaaccaaga atccaattta
     6721 ttaaccagag aagccattga aacagccctc ttgcaactct tggaaaaaaa ggagctgacc
     6781 aagattagta tttctgaatt ggtcaaacgt gcaggtgttt cgcgtgcggc cttttatcgc
     6841 aattatgact ccaaagagga aattttagag agcgtcttta aacgaactgt ccacaatatt
     6901 atggaacagc tgcatcatta cgatttaaag acagaccttt atttggtttg ggttcacctt
     6961 ttccgggaga ccagaaagga agctagagta attcaattgg ccttggatta ccatctggaa
     7021 aaaatctttg tccaagccat gcaggaattt ctagaaaaat accatgggaa atcaaaaggt
     7081 gtcagctctt atcttcattc cttctggagc tcagccatcg tctctgtcct tctaaaatgg
     7141 atcaaggatg gcatgaaggt accagctgaa aagattgcag atttaggttt accatttttt
     7201 aaaaaataga gaaaaaggag aaaagagatg actgaaaaaa gactggcctg ggatgagtat
     7261 tttgcagccc aagccctact aattgcgaat cgttccactt gtaaacgtgc taaagtgggc
     7321 gcgattctgg taaaagataa taaggttatt tccactggtt acaatggttc ggtgtcaggg
     7381 actgagcatt gtattgatca cgaatgtttg gtcattgaag gccactgtgt tcgcaccctt
     7441 cacgctgagg tcaatgctat ccttcaaggt gctgagcgtg gtgttcccaa aggctttaca
     7501 gcctatgtaa cccattttcc ttgtctcaac tgtacaaaac aattgcttca ggtcggctgc
     7561 aagcgcgtgg tttatatcaa ccagtaccga atggacgact acgcccaata cctttatcaa
     7621 gaaaaaggga cagaattgac ccatttacca cttgagacag tacagacagc tcttaaagag
     7681 gctgatctaa tgtaaaaatt atcaaaaata aatggtttag aaagattttt aaaccgtttt
     7741 ttggtataat aagaagaata aattgaaaga aggaattcca aaaatgggaa aaattgaagt
     7801 tattaatcac ccactgattc aacacaaatt gtcaatcttg cgtcgtacag atacttctac
     7861 aaaagctttt cgtgagctag tagatgagat tgcaatgttg atggggtatg aagtacttcg
     7921 tgatcttcca ctagaagatg tggaaatcga aacaccaatt acaaaaacag ttcaaaaaca
     7981 attggcaggt aagaaattgg ccatcgtccc aatcttgcgt gcaggtatcg ggatggttga
     8041 tggtctcttg agcttggttc cagctgctaa agttggccac atcggtatgt accgtgatga
     8101 agaaacactt caaccagttg aatacttggt gaaattgcct gaggacattg accaacgtca
     8161 aatttttgta gtagacccaa tgttggcaac aggtggctca gcaatcttgg ctgttgattc
     8221 tcttaaaaaa cgtggcgcat caaatatcaa atttgtctgc cttgtatctg ctccagaggg
     8281 tgtaaaagcc cttcaagaag ctcatccaga tgtagaaatc tttacagcag ccttggatga
     8341 acgtttgaac gaacacggtt atatcgttcc aggtcttgga gatgctggag accgcttgtt
     8401 cggtacaaaa taagatcgaa aagaagaatg acttggaaaa gcatttctag tcacgaaagg
     8461 aggttgggtt tttgtttctg tctaatgaaa gcagagcaaa aatttgacct tttttgacca
     8521 agatattata atagtcttat cttcagtcat ttgaccaaca aaattaaaac tcaaaaggag
     8581 aaatgaatga ttcctgtagt tattgaacaa acaagccgtg gagaacgttc ttacgatatt
     8641 tactcacgtc ttctcaaaga ccgcatcatt atgctgacag gtccggttga agacaatatg
     8701 gctaactctg ttattgccca attgcttttc ttggatgccc aagatagtac gaaagatatt
     8761 tacctttatg tcaatacacc aggtggttct gtttcagctg gtttggcaat cgtagatacc
     8821 atgaacttta tcaaggcaga tgtccaaacc attgttatgg gaatggctgc atctatgggg
     8881 actgtcatcg catcaagtgg ggcaaaaggc aaacgtttca tgcttccaaa tgctgaatac
     8941 atgattcacc aaccaatggg cggtacaggt ggtggtaccc aacaaactga tatggctatc
     9001 gctgcagaac acttgctcaa aactcgtaat accttggaaa aaatcttggc tgaaaattca
     9061 ggtcagtcaa tggaaaaagt ccatgcagat gcagaacgtg ataactggat gagcgcccag
     9121 gaaacacttg aatatggctt tattgatgaa attatggcca acaattcatt gaactaatga
     9181 tgatagaagg caaactcgac tgggtttgct ttttttggta taatagggag agatttctta
     9241 gaaagaggat ttatcatgtt tgaaaaagtc aatcgctctg gcttgattat ctatctttac
     9301 tataatcgtg atgccaaaaa actgcaggat tatggagata ttacctatca ttccaagaaa
     9361 catcgttact tacaactcta tgttccaact caagaagtgg agcaattggt cggacgcttg
     9421 agcaaggaaa aatttattaa aaaagttagg gtttgtcata tccaagagtt ggaaacaccc
     9481 tttgtgggca atctttatcg ataggaaaac gttatcatcg aaaaagttca aggaaaacat
     9541 tgacaatttt ctgataattc ggtatattct taacagacta tttaagaaat aaggagacaa
     9601 aaagatgaag aaaaaatttg ccctatcgtt tgtggcgctt gcaagtgtag cacttcttgc
     9661 agcctgtgga gaagtgaagt ctggagcagt caacactgct ggtaactcag tagaggaaaa
     9721 gacaattaaa atcgggttta actttgaaga atcaggttct ttagctgcat acggaacagc
     9781 tgaacaaaaa ggtgcccaat tggctgttga tgaaatcaat gccgcaggtg gtatcgatgg
     9841 aaaacaaatc gaagtagtcg ataaagataa taagtctgaa acagctgagg ctgcttcagt
     9901 tacaactaac cttgtaaccc aatctaaagt atcagcagtc gtaggacctg cgacatctgg
     9961 tgcgactgca gctgcggtag cgaacgctac aaaagcaggt gttccattga tctcaccaag
    10021 tgcgactcaa gatggattga ctaaaggtca agattacctc tttattggaa ctttccaaga
    10081 tagcttccaa ggaaaaatta tctcaaacta tgtttctgaa aaattaaatg ctaagaaagt
    10141 tgttctttac actgacaatg ccagtgacta tgctaaaggg attgccaaat ctttccgcga
    10201 gtcatacaag ggtgaaatcg ttgcagatga aactttcgta gcaggtgaca cagactttca
    10261 agcagccctt acaaaaatga aagggaaaga ctttgatgct atcgttgttc ctggttacta
    10321 taatgaggct ggtaagattg taaaccaagc gcgtggcatg ggaattgaca aaccaatcgt
    10381 tggtggtgat ggattcaacg gtgaggagtt tgtacaacaa gcaactgctg aaaaagcatc
    10441 aaacatctac tttatctcag gcttctcaac tactgtagaa gtttcagcta aagctaaagc
    10501 cttccttgac gcttaccgtg ctaagtacaa tgaagagcct tcaacatttg cagccttggc
    10561 ttatgattca gttcaccttg tagcaaacgc agcaaaaggt gctaaaaatt caggtgaaat
    10621 caaggataac cttgctaaaa caaaagattt tgaaggtgta actggtcaaa caagcttcga
    10681 tgcagaccac aacacagtca aaactgctta catgatgacc atgaacaatg gtaaagttga
    10741 agcagcagaa gttgtaaaac cataatagaa aaatgttgaa atagggaatg agcctttgac
    10801 tcactccctg tttcgatatt taatactctt cgaaaatctc ttcaaactgc gtcaacgtcg
    10861 ccttggatta tatatgtgac tgacttcgtc agtcttatct acaacctcaa agcagtgctt
    10921 tgagcaacct gtggctagtt tcctagtttg ctctttgatt ttcattgagt ataagaacct
    10981 atcaaaaagt gagggaaacc cctcgggatt ataaatagaa agagtgaatc ttatgctcca
    11041 acaactcgta aatggtttga ttctaggtag tgtttacgcg ctgttagccc taggatatac
    11101 catggtttac ggaattatca agctcatcaa cttcgcccat ggtgatattt atatgatggg
    11161 agcctttatc ggttatttct tgatcaattc tttccaaatg aatttctttg tagcgcttat
    11221 tgtagctatg ctagcgacag ctattcttgg tgtcgtgatt gagtttcttg cttaccgacc
    11281 tttgcgccac tctactcgta ttgctgtttt gattacggct attggggttt ctttcctatt
    11341 ggagtatgga atggtctatc tggttggtgc caatacccgt gccttccctc aagcgattca
    11401 aacagttcga tatgatttgg gaccaattag cttaacaaat gtgcagttaa tgattttggc
    11461 catttccttg attttgatga ttttgttaca agtcattgtc caaaagacta agatggggaa
    11521 agccatgcgt gcagtatcag tagatagcga cgcggcgcaa ttgatgggga tcaatgtaaa
    11581 ccgtacgatt agctttacct tcgctttggg ttctgctctt gcgggtgcgg ctggtgttct
    11641 gattgctctt tattataact ctcttgagcc tttgatgggg gttactccag gtcttaaatc
    11701 tttcgttgcc gcagtacttg gtggtatcgg aattattcct ggtgcggctc ttggtggctt
    11761 tgtgattggt ctattggaaa cctttgcgac agcctttggg atgtcagatt tccgtgatgc
    11821 cattgtttat ggaatcttgt tgttgatctt gattgtccgc ccagctggta tccttggtaa
    11881 gaatgtgaaa gagaaggtgt aaacgatgaa ggaaaattta aaagttaata ttctatggtt
    11941 actccttttg ttagctggct atagcttgat tagtgtactg gtttcagtcg gagtacttaa
    12001 tctattctat gtacagattt tacaacaaat tggaattaat attattttgg ctgttggtct
    12061 caacttaatc gttggttttt caggacaatt ttcacttggt catgctggtt tcatggcgat
    12121 tggtgcctat gcagcagcta ttattggttc taaatcacca acctacggtg ccttctttgg
    12181 agctatgctt gtagggactt tgctttcagg agcagttgcc ttacttgtcg gcattccaac
    12241 cttgcgcttg aagggggact atcttgcggt agcaactctg ggtgtttctg aaattatccg
    12301 tatctttatc atcaatggtg gaagccttac aaatggtgcg gcaggtatct tagggattcc
    12361 taactttaca acttggcaaa tggtttactt ctttgtcgtg attacaacca ttgcaacctt
    12421 gaacttcttg cgtagcccaa ttggtcgctc aaccctctct gttcgtgaag atgaaatcgc
    12481 tgctgagtca gttggggtta atacgactaa aattaaaatc atcgcttttg tctttggtgc
    12541 cattactgca agtattgctg ggtcacttca ggcaggattt atcgggtctg ttgtaccgaa
    12601 agattacacc ttcatcaact caatcaacgt tttgattatt gttgtatttg gtggactcgg
    12661 ttccattaca ggtgcgattg tttcggctat tgttctggga attttgaata tgcttctcca
    12721 agatgttgct agtgtgcgta tgattattta cgctttggcc ttggtattgg taatgatttt
    12781 cagaccaggt ggactccttg gaacatggga actgagccta tcacgtttct ttaaaaaatc
    12841 taagaaggag gaacaaaact aatggcatta cttgaagtaa aacagttaac caaacatttt
    12901 ggtggtctaa cagctgttgg agatgtgact cttgaattga acgaagggga actggttgga
    12961 ttaatcggtc caaacggagc tgggaaaacc acccttttca accttttgac cggtgtttat
    13021 gaaccaagcg agggaacagt aaccctagat ggtcaccttt tgaatgggaa atcaccttat
    13081 aagattgcct ctttgggact tggacgtact ttccaaaata tccgtctctt taaagattta
    13141 acagttttag ataatgtttt gattgctttt ggaaaccatc acaaacagca tgtttttact
    13201 agtttcttac gcttaccagc tttttacaag agtgaaaaag aattaaaggc taaagctttg
    13261 gaattgttga aaatctttga tttagatggt gatgcagaga ctcttgctaa aaatctttcc
    13321 tacggacaac aacgtcgttt ggaaattgtt cgtgcccttg ctacggaacc taaaattctc
    13381 ttcttagatg aaccagcagc aggtatgaac ccacaggaaa cagccgaatt gactgagtta
    13441 attcgtcgta tcaaagatga gtttaagatt acaatcatgt tgattgaaca cgatatgaat
    13501 ctggtcatgg aagtaacaga acgtatctac gtacttgaat atggccgttt aatcgctcaa
    13561 ggaactccag acgaaattaa gaccaataaa cgcgttatcg aagcttatct aggaggtgaa
    13621 gcctaatgtc tatgttaaaa gttgaaaatc tttctgtgca ttacggtatg atccaagcag
    13681 ttcgtgatgt aagctttgaa gttaatgaag gagaagttgt ttcccttatc ggtgccaacg
    13741 gtgcaggtaa gacaactatt cttcgcacct tgtcaggttt ggttcgacca agttcaggaa
    13801 agattgaatt tttaggtcaa gaaatccaaa aaatgccagc tcagaaaatc gtggcaagtg
    13861 gtctttcaca agttccagaa ggacgccacg tctttcctgg cttgactgtt atggaaaatc
    13921 ttgaaatggg agctttctta aagaaaaatc gtgaagaaaa tcaagctaac ttgaagaagg
    13981 ttttctcacg ctttcctcgt cttgaagaac ggaagaacca agatgcagcc actctttcag
    14041 ggggggaaca acaaatgctt gccatgggac gcgccctcat gtcaacacca aaacttcttc
    14101 ttttagatga accatcaatg ggacttgccc caatctttat ccaagaaatt tttgatatca
    14161 ttcaagatat tcagaagcaa ggaacaacgg tcctcttgat tgaacaaaat gccaataaag
    14221 cacttgcaat ctctgaccga ggatatgtac tggaaacagg gaaaatcgtc ctatcaggaa
    14281 caggaaaaga actcgcttca tcagaagaag tcagaaaagc atatctaggt ggctaaaaca
    14341 atccagtgga ttgttttagt cggcagatgg agattacgaa gtaatcatca atatagtccg
    14401 ggggaccttt ttagtcggta gattgagatt gcaaacaaat ctgcatctac attgaaagct
    14461 taatttctaa taattgaaaa aatcgaatga aaaatttctt accttcattc acagagctcg
    14521 atttcagagc tctttttgct agcttattca tacttttctg aatttcgaaa aagaaatgta
    14581 agcgtttgat agatttacaa aaagattgta taatggggat aagaatagaa aaggagaagt
    14641 ctcatggcag ttaaagattt tatgacccgc aaggtagttt atattagtcc agatacaaca
    14701 gtatctcatg cagcagattt gatgagagag caaggtttgc accgtctgcc tgttatcgaa
    14761 aatgatcaat tagttggttt ggtgactgag ggaaccattg cacaagcaag tccatctaaa
    14821 gcaacaagtc tttctatcta tgagatgaat tatcttctga ataagacaaa agtaaaagat
    14881 gtcatgattc gcgatgttgt cactgtctca ggctatgcta gtctagaaga tgcaacttat
    14941 ctgatgttga aaaataagat tagtattctc cctgtcgtag ataaccatca agtatacgga
    15001 gttattactg accgtgacgt tttccaagcc tttcttgaaa ttgcaggtta tggcgaagaa
    15061 gggattcgtg tacgctttgt tacagaagat gaagttggtg ttcttggaaa aattgtttct
    15121 ttgattgtag aagaaaattt gaatatctcc catacagtca atattccgcg taaggatggt
    15181 aaggtgatta tcgaagtgca aatcgatgga tcaattgatt taccagcctt gaaagaaaaa
    15241 tttgaagcaa atggtattca agtggaagaa atcgctcgca cttcagcaaa agtcttgtaa
    15301 gaagggaagc ccaaaggctt cttttttcat gaaaagggga ttagagcaaa agatggaaag
    15361 aaatgataaa atatgctata atgaaatgat gtaaaaaagg agtatttatg gacatttcag
    15421 taattcgtca gaaaattgac gcaaatcgtg aaaaattagc ttctttcagg gggtctcttt
    15481 gacctcgaag ggctagagga agagattgcc atcttggaaa acaagatgac agaacctgat
    15541 ttttggaacg ataatattgc ggcccaaaaa acgtcgcaag aattgaatga attaaaaaac
    15601 acttacaata ccttccataa gatggaagag ttgcaggatg aagtcgaaat tttattggat
    15661 tttttggctg aagacgagtc agtgcatgat gaactggtag cgcagttagc cgaacttgat
    15721 aagataatga ccagctacga gatgactcta ctcttgtcag aaccttatga ccacaacaat
    15781 gccatcttgg aaatccatcc aggttctggt ggtactgagg cgcaggactg gggtgatatg
    15841 ttgcttcgta tgtatactcg ttatggtaat gctaaaggct ttaaagtgga agtgttggat
    15901 taccaagcag gtgatgaggc tggtattaag tcggtaactt tatcatttga agggcctaat
    15961 gcctatggtc tcctcaagtc agaaatgggt gttcatcgct tagtgcgaat ctcaccattt
    16021 gactctgcca aacgtcgcca tacctctttc acatctgtag aagtgatgcc agaattggat
    16081 gatactattg aagtggaaat ccgtgaagat gatatcaaga tggatacctt ccgttcaggt
    16141 ggtgccggtg gacaaaacgt caataaggtt tcaacaggtg tacgtttaac ccacattcca
    16201 actggaattg ttgtccaatc aacagtggat cgtacccagt atggaaatag agatcgcgcc
    16261 atgaagatgt tgcaggctaa gctctatcaa atggagcaag agaagaaggc tgcggaggta
    16321 gattctctca aaggtgagaa aaaggagatc acttggggaa gtcaaatccg ttcttatgtc
    16381 ttcacgcctt atactatggt aaaagatcac cgaactagct atgaggttgc tcaggtagat
    16441 aaggttatgg atggggacct agatggtttt atcgatgctt atctcaagtg gcgaattagc
    16501 taagatagaa aggaactcac atgtcaatta ttgaaatgag agatgtcgtt aaaaaatacg
    16561 acaacggaac gactgctcta cgcggtgttt cggttagcgt tcaaccgggg gaatttgctt
    16621 acatcgtagg accttcagga gcagggaagt caacttttat tcgttctctg tatcgtgaag
    16681 taaaaatcga taaaggaagt ctatcagttg ctggttttaa tctggttaag atcaaaaaga
    16741 aagatgtccc gcttctacgt cgtagtgttg gggttgtctt ccaggattat aaactgttac
    16801 caaagaaaac tgtctatgaa aatattgctt acgctatgga agtaatcggg gaaaatcgcc
    16861 gtaatatcaa aagacgagtg atggaagttt tggacttggt tggattgaag cataaggttc
    16921 gttctttccc aaatgaactc tcaggtgggg agcaacagcg gattgcgatt gcgcgtgcaa
    16981 ttgtaaataa tcccaaagta ttgatagctg atgagccaac aggaaatctg gatccggata
    17041 attcatggga aattatgaat ctcttggaac ggattaacct acaaggaaca actattttga
    17101 tggcgactca taatagccag attgtaaata ccttgcgcca ccgtgtcatt gccattgaaa
    17161 atggccgtgt cgttcgtgac gaatcaaaag gagagtatgg atacgatgat tagtagattt
    17221 tttcgccatt tatttgaagc cttaaaaagt ttgaaacgaa atggttggat gacagtagct
    17281 gctgtcagtt cagtcatgat tactttgacc ttggtggcaa tatttgcatc tgttattttc
    17341 aatacagcga aactagctac agatattgaa aataatgtcc gtgtagtagt ttatatccga
    17401 aaggatgtgg aagataatag tcagacaatt gaaaaagaag gtcaaactgt tacaaataat
    17461 gactaccaca aggtatatga ttctttgaag aacatgtcta cggttaaaag tgttaccttt
    17521 tcaagtaaag aagaacaata tgaaaaatta accgagataa tgggagataa ctggaaaatc
    17581 tttgaaggag atgccaatcc tctctatgat gcctatattg tagaggcaaa cactccaaat
    17641 gatgtaaaaa ctatagccga agatgctaaa aaaattgaag gtgtctctga ggttcaagat
    17701 ggcggtgcca atacagaaag actcttcaag ttagcttcat ttatccgtgt ttggggacta
    17761 gggattgctg ctttgttaat ttttatcgca gttttcttga tttcaaatac cattcgtatt
    17821 accattattt cccgcagtcg cgaaattcaa atcatgcgct tggtcggagc taaaaacagt
    17881 tatatccgtg gaccgttctt gttagaagga gcctttatcg gtttattggg agctatcgca
    17941 ccatctgttt tggtctttat tgtttatcaa attgtttacc aatctgtcaa caaatcgttg
    18001 gtagggcaaa atctatccat gattagtcca gatttattta gtccgttgat gattgcccta
    18061 ctatttgtga ttggggtttt cattggttca ttgggatcag gaatatccat gcgccgattc
    18121 ttgaagattt aggtaaaata gctgctttta tgaggagatt gtaaaatctc cttttttgct
    18181 acaagagttt ttgaaaagag atgcgcagaa gaaaagagct tccaaagaag tcccccagag
    18241 aagacttctt gatggctaat ttgaacttga aatttggcgc actagaaatt ttttagaaaa
    18301 aagtgtaatt tttttataaa agcctttaca aaaaaaatta aagtggtata attaaatcat
    18361 agaaagtgca aacgttttcg taaaacgttt gcctaaataa aaataaagga gatttgaatg
    18421 atgaaagata cattcaaaaa tgtcttgtct ttcgaatttt ggcaaaaatt cggtaaggct
    18481 ttgatggtag ttatcgcggt tatgccggct gctggtttga tgatttcaat cggtaagtct
    18541 atcgtgatga ttaacccaac ctttgcacca cttgtcatca caggtggaat tcttgagcaa
    18601 atcggttggg gggttatcgg taaccttcac attttgtttg ccctagccat tggaggaagc
    18661 tgggctaaag aacgtgctgg tggtgctttc gccgctggtc ttgccttcat cttgattaac
    18721 cgtatcactg gtacaatctt tggtgtatca ggcgatatgt tgaaaaatcc agatgctatg
    18781 gtaactactt tctttggtgg ttcaatcaaa gttgctgatt actttatcag tgttcttgaa
    18841 gctccagcct tgaacatggg ggtattcgta gggattatct caggttttgt aggggcaact
    18901 gcttacaaca aatactacaa cttccgtaaa cttcctgatg cactttcatt cttcaacggg
    18961 aaacgtttcg taccatttgt agttattctt cgttcagcaa tcgctgcaat tctacttgct
    19021 gctttctggc cagtagttca aacaggtatc aataacttcg gtatctggat tgccaactca
    19081 caagaaactg ctccaattct tgcaccattc ttgtatggta ctttggaacg tttgctcttg
    19141 ccatttggtc ttcaccacat gttgactatc ccaatgaact acacagctct tggtggtact
    19201 tatgacattt taactggtgc agctaaaggt actcaagtat tcggtcaaga cccactatgg
    19261 cttgcatggg taacagacct tgtaaacctt aaaggtactg atgctagtca atatcaacac
    19321 ttgttagata cagtacatcc agctcgtttc aaagttggac aaatgatcgg ttcattcggt
    19381 atcttgatgg gtgtgattgt tgctatctac cgtaatgttg atgctgacaa gaaacataaa
    19441 tacaaaggta tgatgattgc aacagctctt gcaacattct tgacaggggt tactgaacca
    19501 atcgaataca tgttcatgtt catcgcaaca cctatgtatc ttgtttactc acttgttcaa
    19561 ggtgctgcct tcgctatggc tgacgtcgta aacctacgta tgcactcatt cggttcaatc
    19621 gagttcttga ctcgtacacc tattgcaatc agtgctggta ttggtatgga tatcgttaac
    19681 ttcgtttggg taactgttct ctttgctgta atcatgtact ttatcgcaaa cttcatgatt
    19741 caaaaattca actacgcaac tccagggcgc aacggaaact acgaaactgc tgaaggttca
    19801 gaagaaacca gcagtgaagt gaaagttgca gcaggctctc aagctgtaaa cattatcaac
    19861 cttcttggtg gacgtgtaaa catcgttgat gttgacgcat gtatgactcg tcttcgtgta
    19921 actgttaaag atgcagataa agtaggaaat gcagagcaat ggaaagcaga aggagctatg
    19981 ggtcttgtca tgaaaggaca aggggttcaa gctatctacg gtccaaaagc tgacattttg
    20041 aaatctgata tccaagatat ccttgattca ggtgaaatca ttcctgaaac tcttccaagc
    20101 caaatgactg aagcacaaca aaacactgtt cacttcaaag atcttactga ggaagtttac
    20161 tcagtagcag acggtcaagt tgttgctttg gaacaagtaa aggatccagt atttgctcaa
    20221 aaaatgatgg gtgatggatt tgcagtagaa cctgcaaatg gaaacattgt atctccagtt
    20281 tcaggtactg tatcaagcat cttcccaaca aaacatgctt ttggtattgt gacggaagca
    20341 ggtcttgaag tattggttca cattggtttg gacacagtaa gtcttgaagg taaaccattt
    20401 acagttcatg ttgctgaagg acaaaaagtt acagcaggag atctccttgt cacagctgac
    20461 ttggatgcta tccgtgcagc aggacgtgaa acttcaacag tagttgtctt cacaaatggt
    20521 gatgcaatta aatcagttaa attagaaaaa acaggttctc ttgcagctaa aacagcagtt
    20581 gctaaagtag aattgtaata tacttgaggt tggaagctgt attccaacct cttattttgg
    20641 gagaaaagaa tgaaattttt aacactcaat actcacagtt ggatggagaa agaagcagag
    20701 gaaaaattcc agattttgct tgaagatatt cttgaaaagg actatgattt gatttgtttc
    20761 caagaaatca atcaggagat gacctcgtca gaggtggagg ttaatgacct ttatcaagct
    20821 ttgccagcag ctgagcctat tcaccaagac cattatgtta gactcttggt tgaaaagttg
    20881 ttagagcaag ggaaaaatta ctactggacc tgggcttata accatatcgg ctatgaccgc
    20941 taccatgaag gtgtggctat cttgtctaaa acacctattg aagccagaga aattttggtt
    21001 tcagatgtgg atgatccaac agactatcat actcgccgtg ttgccctagc tgaaactgta
    21061 gtcgatggca aggagctagc agttgccagt gttcatctct cttggtggga taaaggtttc
    21121 caagaagaat gggcacgatt tgaggctgtc ttgaaaaaat tgaacaagcc acttttacta
    21181 gctggagatt ttaacaaccc agcaggtcag gaaggttacc aagctatttt agctagtcca
    21241 ttaggcttac aagacgcatt tgaagttgct caagagaaaa gtggtagcta tactgttccg
    21301 cctgaaattg atggctggaa agggaacact gaaccccttc gaatcgatta tgtctttact
    21361 accaaagagt tagcggtgga aaatttacat gtcgtatttg atggtaacaa gagtctacaa
    21421 gtgagtgatc actatggctt gaatgctata ttaaactgga aataataact gaaaagaggt
    21481 tggaactata aaattccagc cttttcttac tagagaagct actggaaata gcctaaataa
    21541 gtgagactac tgtaatggaa taaaatatgg tataattgat aaggtagata gaatcgagga
    21601 tgttatgtca tttacgaaat ttcaatttaa aaactatatt agagaagcct tgaaggagtt
    21661 aaaatttaca actccaacag aggtgcaaga caagttgatt cctattgttt tggcaggtcg
    21721 tgacctagta ggagaatcaa aaacaggttc aggtaagact catactttct tgttaccgat
    21781 tttccagcaa ttagatgaag ctagcgatag tgtacaagca gtgattactg caccgagtcg
    21841 tgagttggct actcaaattt accaagtagc gcgtcagatt tcagctcact cagatgtcga
    21901 agttcgtgtg gttaattatg tgggtggtac ggataaggct cgccagattg agaaattggc
    21961 aagcaatcag cctcatattg ttattggaac accaggccgt atctacgact tggttaaatc
    22021 tggtgattta gctattcata aagccaagac atttgttgtt gatgaagcag atatgacctt
    22081 ggatatggga ttcttggaaa ctgttgataa gattgctggc agtcttccaa aagacttgca
    22141 attcatggtc ttctcagcga ctatcccaca aaaactgcaa ccattcttga aaaaatactt
    22201 atcaaatcct gttatggaga aaattaagac caaaacggtt atttctgaca ccattgataa
    22261 ttggttgatt tcgaccaagg gacatgataa gaatgctcaa atttaccagt tgactcagtt
    22321 gatgcagccg tatttggcaa tgatttttgt taacactaaa acgcgtgctg atgaattgca
    22381 ttcatatctg actgctcaag gcttgaaggt tgcaaaaatc catggcgata ttgcccctcg
    22441 tgaacgcaag cgaatcatga atcaggtgca aaatctggat tttgagtata ttgtcgcaac
    22501 agatttggca gcgcgtggga ttgacattga aggtgtcagc catgtcatca atgatgccat
    22561 tccgcaagac ttatcttttt ttgttcatcg tgttggtcgt actggacgaa atggcctacc
    22621 aggtacagct attacccttt atcagccaag tgatgactcg gatatccgtg agttggagaa
    22681 attgggaatc aagtttagtc ctaagatggt caaagacggg gaatttcaag atacctatga
    22741 ccgtgatcgt cgtgccaacc gtgagaaaaa acaagataaa cttgatatcg aaatgattgg
    22801 tttggttaaa aagaaaaaga aaaaagtcaa accgggttat aagaagaaaa ttcaatgggc
    22861 ggttgatgaa aagcgccgta aaaccaagcg tgctgaaaat cgcgctcgcg gtcgtgcaga
    22921 gcgtaaagct aaacgccaaa cattttaata gaaattgttg gagtattgag ctccaacttt
    22981 ttgctttatg agaacgaact atctaaaccg aaacactaca ttaaagactg caaattgcga
    23041 ttaaaaatgg tataatgata aagttatata gtcccgataa gatggtaggt atttattacg
    23101 aagagttttc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
    23161 ttatgtcaga gcgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
    23221 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
    23281 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
    23341 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
    23401 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
    23461 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
    23521 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
    23581 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
    23641 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
    23701 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
    23761 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
    23821 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
    23881 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
    23941 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
    24001 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
    24061 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
    24121 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
    24181 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
    24241 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
    24301 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
    24361 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
    24421 tccattttgc gaaagtagag atttacatgt atagtagatt gaaactagaa tagtacacct
    24481 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
    24541 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
    24601 taatcttggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
    24661 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
    24721 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ctaatacact agctgtttcc
    24781 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
    24841 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
    24901 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
    24961 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
    25021 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
    25081 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
    25141 actattattt ggattatctt ttggatttgc aggaaaaaga gtcgaaccga actttcttct
    25201 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
    25261 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
    25321 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
    25381 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
    25441 cagctatttt caacaaatat ccgctcaagt ttgtcaactg cgttaactct atcggaaacg
    25501 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
    25561 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
    25621 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
    25681 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
    25741 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
    25801 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatcaga
    25861 agaaagaagg gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
    25921 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaaa
    25981 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
    26041 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
    26101 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
    26161 atgatgagct taagtcattt gaggaatacc ttgacaatcc ttctccaaca accaagttga
    26221 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
    26281 atgccaaggc cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
    26341 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
    26401 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
    26461 cggattctgt tatcgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
    26521 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
    26581 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
    26641 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
    26701 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
    26761 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
    26821 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
    26881 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
    26941 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
    27001 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
    27061 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
    27121 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
    27181 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
    27241 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
    27301 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcctgagaaa
    27361 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
    27421 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
    27481 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
    27541 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
    27601 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
    27661 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
    27721 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
    27781 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
    27841 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
    27901 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
    27961 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
    28021 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
    28081 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    28141 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    28201 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    28261 cgactcaaac caaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    28321 agcattctca gaaagaggac aagggacaac gtcattttgt cattcgtcag aagtgagtag
    28381 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    28441 atgggtattg tagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    28501 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    28561 gctcaatgac cagtttgtgg tcaatccctt gaaacaacgt attgtgcaag agtctgctga
    28621 tggtacagtc aaatatctct ttgaattgcc cgacggtatg ttaattgaga ctgtactcat
    28681 gcgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    28741 taccttctgt gcctctggtt tgattaagaa gcaacgtgac ctcaataacg gtgaaatcgt
    28801 agcgcaaatc atgctggttc agaaatactt tgctgagcgt ggtcaggatg aacgcgtcag
    28861 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    28921 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcatgatttc
    28981 aacctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    29041 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga aaattaaccg
    29101 tgcctttccg attgaaaaac tctttgctgc tattgaatac tatattgaga caacaaaccg
    29161 tcgtgtaacc tttgaatata tcatgcttaa tgaagtcaac gacggtgtag aacaagcctt
    29221 ggaattggct gaattgctca agaacatcaa gaaattgtct tatgtaaact tgattcctta
    29281 taacccagtt agtgagcatg accaatatag ccgtagtccc aaagagcgcg tgttggcttt
    29341 ctatgatacg cttaagaaaa aaggggtcaa ctgtgtggtt cgtcaagagc atggtacaga
    29401 tattgacgca gcttgtggac aattgcgctc taacacaatg aaacgtgacc gccagaaggc
    29461 agtcgcagcg gtaaatcctt aatgatgaag aagacttata atcatatttt ggtctgggga
    29521 gtcattttct atagcatttg cattgtctat ttttgcttta ctcctcaaga acaatctacc
    29581 gtgggagtgg gaactccagg tattcagcat cttggacgcc tggtttttct tttgactcct
    29641 ttcaattctc tctggaaact gggcgaagtg agtgacattg gacaattatg ttggattttt
    29701 ttacaaaatg tcctcaatgt cttcttattt tttcctctga ttttccaact cctttatcta
    29761 tttccaaatt tgcggaaaac aaaaaaggtc cttcttttta gttttcttgt gagtcttgga
    29821 atcgagtgta cgcaattaat cttggacttt ttctttgatt tcaatcgcgt ctttgagatt
    29881 gatgatttgt ggaccaatac tttgggtggc tatctggctt ggctccttta taaacgatta
    29941 cataaaaaca agataaggaa ttaaaatgag tattttagaa gttaaaaatc tgagtcacgg
    30001 ttttggtgac cgtgcaattt ttgaagatgt gtccttccgt ctcctcaagg gagaacatat
    30061 cggcctggtc ggtgccaatg gtgaaggaaa atcaaccttt atgagtatcg tgactggtaa
    30121 aatgctgcca gatgaaggaa aggttgagtg gtccaaatat gtgacggctg gttacttgga
    30181 tcagcactct gtccttgctg aaagacagtc ggtgcgtgat gttctccgta cggcttttga
    30241 tgagcttttc aaagctgaag ctcgtatcaa tgacctctat atgaaaatgg ctgaagacgg
    30301 cgcggatgtt gatgctctca tggaagaagt aggagaactt caagaccgtc tggagagtcg
    30361 tgatttctat accttggatg ctaagattga cgaagtagcg cgtgctcttg gtgttatgga
    30421 ctttggcatg gatacggatg taacttcttt gtcaggtggg caaagaacca aggtgctttt
    30481 ggcaaaactt ctccttgaaa agcctgatat tttgctgttg gacgagccga ccaactactt
    30541 ggatgctgag catattgatt ggctcaagcg ctatctccaa aactatgaga atgcctttgt
    30601 tctcatttcg cacgatattc cattcctcaa tgacgttatc aatattgtct atcatgtgga
    30661 aaatcaacag ctgacgcgtt actctggtga ctactaccag ttccaagaag tttatgctat
    30721 gaagaaatct cagctagagg cagcctacga acgccagcag aaagagattg cagacctcaa
    30781 ggactttgtg gctcgtaata aagcccgtgt tgcaactcgt aatatggcta tgtctcgtca
    30841 aaagaaattg gataagatgg atattatcga actccaaagt gagaaaccaa aaccatcctt
    30901 tgatttcaaa ccagctcgta caccagggcg ctttatcttc caagccaaga acttgcaaat
    30961 tggttacgac cgtcctctta ctaagccttt aaatcttacc ttcgaacgca atcaaaaggt
    31021 tgcgattatt ggtgctaatg gtattggaaa aacaactctc ttgaagagtc tcttgggcat
    31081 tatctcgcca atcgctgggg aagtggagcg tggagattat ttagaacttg gttattttga
    31141 gcaggaagta gaaggcggta atcgccaaac tcctcttgaa gctgtctgga atgcctttcc
    31201 tgcccttaat caagcagaag tccgtgcagc ccttgcccgt tgtggtttga caaccaaaca
    31261 tattgaaagc cagattcaag tattatcagg gggagagcaa gccaaggttc gtttctgtct
    31321 cttgatgaat cgtgaaaaca acgttttagt gctggacgag ccgaccaacc atttggatgt
    31381 ggatgcaaag gatgagctca aacgcgctct caaagaatat aggggatcta tccttatggt
    31441 ctgccacgag ccagactttt atgaaggctg gatagaccaa atatgggatt ttaataattt
    31501 aacttaagaa tgagagtaaa agaaatacag taccgaatgt ggatactgta tttttttggt
    31561 ttttaagatt taaaatcgta gtctttcacc acttcgatgc tgtcgattgt gatagcagta
    31621 gttggcttgt ctttttcatc tttttcggcc ttagcaatct tatccacaac atccataccg
    31681 tcaatcactt gaccaaagac tgggtgtttg ccatctagac tagggtttcc accttctttg
    31741 taggcttcga taattttctg tggatacttg cttgtaggga gtttagaaga ggtatctgta
    31801 gagttttggt tgatgaagaa ctggctgcca ttggtgtttg gttgaccagt attagccata
    31861 gcaagagcac cgcggatgtt atacaaataa ggagtaatct cgttcttgaa accagttcct
    31921 ttgtctttag tcttatcctt gtcatgccag atggactgac cacctgtacc gtcccctttt
    31981 ggatctccag tttggaccat aaagccatcg atgacacggt ggaaggtaat accgttatag
    32041 tagccttctt tggcgtgagt gaggaaattt tcaaccgcta gaggagcgag tttagggaag
    32101 agtttaatgc gaatatcacc ttggcttgtg tggagaatca cttcggcttc atcttcagca
    32161 acttccttag atagttgtgg gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc
    32221 ttggcagatt gggcagctac tttggaactt tcttcagcag caagactgga atcaacataa
    32281 tcatcaccac gcagactgcg ttggacgctg ctacacccag ctagggctac agtagacagt
    32341 aaaagaaggg ttgctagttt tttcattctg atcctctcaa aaattcattt ataccattgt
    32401 accctaaaag gaagtggatt tcaaatatta gtagtttaca gaactggctt agataatagt
    32461 tgggatttca tcatcatctt gaaaatcttc aacttcttcc ccagtaaatg gtttctgaaa
    32521 agaacttagt ataaaacggg caattggttc aacaattagg aaatttagag gaagagctgc
    32581 aataaagttt acgaaccagg cgcttagata ggtattgggt gtgatagcaa tgccattgta
    32641 aaaaagtcca tagaaggaca tgaaagtgac cagctaattc ttcttctgaa aaatgctcat
    32701 gaagggcttg atccaggtcg caagatttca ttttagaaag tccagtaact cccttcttct
    32761 tcaggatatt ctttttcatg gtattattta gatggtcaag tgagtcaaaa gaagtttcga
    32821 caagagcata ccctttttct accagagttt ttagatgttt aggggcatca ataccataag
    32881 tgtactcaaa gtattttgga aaccagatct taagaaagct cgtaaagcta gccagttctc
    32941 taaacgctaa gaactagcta caacacagca tttacaacac ttcatggttc acaccatggg
    33001 gtgtttttta atgattttaa gcaaaattca cacttaattg aaagttattt aaattagatg
    33061 aaaatttatt ttttgaaaaa gtgggaaaac attgattcta agcgaatttt gaatcatatt
    33121 cgaatgggag tttttaaaat catgtttcag tggtaaaagt accaaactgg attctccata
    33181 gtaaaatgat atctcctgct agtgaatcat ctactaataa gtccatattt cgcttgggaa
    33241 cgggcttggg acttagaagc caagtatcca actctcgttc aggcgatatg aagggtttga
    33301 cttgg
//
LOCUS       DAVLUM010000022        32206 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLUM010000022 DAVLUM010000000
VERSION     DAVLUM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.022"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            67..1056
                     /gene="manX"
                     /locus_tag="VYN42_000840"
     CDS             67..1056
                     /gene="manX"
                     /locus_tag="VYN42_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1461939.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            1084..1887
                     /locus_tag="VYN42_000841"
     CDS             1084..1887
                     /locus_tag="VYN42_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1461940.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            1911..2822
                     /locus_tag="VYN42_000842"
     CDS             1911..2822
                     /locus_tag="VYN42_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1461941.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2878..4212)
                     /gene="pepC"
                     /locus_tag="VYN42_000843"
     CDS             complement(2878..4212)
                     /gene="pepC"
                     /locus_tag="VYN42_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1461942.1"
                     /translation="MNAIQESFTNKLFANYEANVKYKAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(4430..5152)
                     /locus_tag="VYN42_000844"
     CDS             complement(4430..5152)
                     /locus_tag="VYN42_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1461943.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(5465..5695)
                     /locus_tag="VYN42_000845"
     CDS             complement(5465..5695)
                     /locus_tag="VYN42_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1461944.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(5705..6946)
                     /locus_tag="VYN42_000846"
     CDS             complement(5705..6946)
                     /locus_tag="VYN42_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1461945.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(6968..7120)
                     /locus_tag="VYN42_000847"
     CDS             complement(6968..7120)
                     /locus_tag="VYN42_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461946.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(7141..7419)
                     /locus_tag="VYN42_000848"
     CDS             complement(7141..7419)
                     /locus_tag="VYN42_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1461947.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(7412..7675)
                     /locus_tag="VYN42_000849"
     CDS             complement(7412..7675)
                     /locus_tag="VYN42_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1461948.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(7777..12168)
                     /locus_tag="VYN42_000850"
     CDS             complement(7777..12168)
                     /locus_tag="VYN42_000850"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1461949.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFINKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMNVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(12272..14353)
                     /gene="fusA"
                     /locus_tag="VYN42_000851"
     CDS             complement(12272..14353)
                     /gene="fusA"
                     /locus_tag="VYN42_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1461950.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(14777..15247)
                     /gene="rpsG"
                     /locus_tag="VYN42_000852"
     CDS             complement(14777..15247)
                     /gene="rpsG"
                     /locus_tag="VYN42_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1461951.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDATNNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(15267..15680)
                     /gene="rpsL"
                     /locus_tag="VYN42_000853"
     CDS             complement(15267..15680)
                     /gene="rpsL"
                     /locus_tag="VYN42_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1461952.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16097..19960
                     /gene="spuA"
                     /locus_tag="VYN42_000854"
     CDS             16097..19960
                     /gene="spuA"
                     /locus_tag="VYN42_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1461953.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESGISSPGNANASLEKTEEKPATEPP
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGSVKIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENK
                     PSQATADSQAEQPAQEAQEASVKEAVRNESVENSSKENIPATPDKQAELPNTGIKNEN
                     KLLFAGISLLALLGLGFLLKNKKEN"
     gene            complement(20060..21109)
                     /locus_tag="VYN42_000855"
     CDS             complement(20060..21109)
                     /locus_tag="VYN42_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1461954.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            21166..21243
                     /locus_tag="VYN42_000856"
                     /pseudo
     CDS             21166..21243
                     /locus_tag="VYN42_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21381..23189)
                     /gene="glmS"
                     /locus_tag="VYN42_000857"
     CDS             complement(21381..23189)
                     /gene="glmS"
                     /locus_tag="VYN42_000857"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1461955.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(23382..24761)
                     /gene="bglA"
                     /locus_tag="VYN42_000858"
     CDS             complement(23382..24761)
                     /gene="bglA"
                     /locus_tag="VYN42_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1461956.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(24861..26714)
                     /locus_tag="VYN42_000859"
     CDS             complement(24861..26714)
                     /locus_tag="VYN42_000859"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1461957.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(26727..27986)
                     /gene="rseP"
                     /locus_tag="VYN42_000860"
     CDS             complement(26727..27986)
                     /gene="rseP"
                     /locus_tag="VYN42_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1461958.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(28008..28811)
                     /locus_tag="VYN42_000861"
     CDS             complement(28008..28811)
                     /locus_tag="VYN42_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1461959.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(28820..29578)
                     /locus_tag="VYN42_000862"
     CDS             complement(28820..29578)
                     /locus_tag="VYN42_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1461960.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(29809..30381)
                     /locus_tag="VYN42_000863"
     CDS             complement(29809..30381)
                     /locus_tag="VYN42_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1461961.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(30362..31333)
                     /gene="ruvB"
                     /locus_tag="VYN42_000864"
     CDS             complement(30362..31333)
                     /gene="ruvB"
                     /locus_tag="VYN42_000864"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1461962.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            31494..31586
                     /locus_tag="VYN42_000865"
     CDS             31494..31586
                     /locus_tag="VYN42_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1461963.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT         9328 a         7525 c         6219 g         9134 t
ORIGIN      
        1 ttatacttaa acagtcttaa agttttctta aatgaaaact aaaacaaaaa aggaggaatg
       61 acaataatga gtatcggaat cattattgcg agccacggcg aatttgctgc gggtattcat
      121 cagtcaggat ctatgatctt tggtgaacaa gaaaaggttc aagttgtgac ctttatgcca
      181 aatgaaggtc ctgatgatct atacgctaag tttaataacg ctgttgctgc atttgacgca
      241 gaagatgagg ttctagtttt ggctgacctt tggagtggtt ctccatttaa ccaagctagt
      301 cgcgtgatgg gagaaaatcc tgagcgtaag tttgccatca tcacaggact taacttaccg
      361 atgttgattc aagcctacac agagcgcctc atggacgctg ctgcaggtgt agaaaaagtc
      421 gctgctaata tcattaaaga agccaaagat ggcatcaaag ctcttccaga agagctaaat
      481 ccagttgaag aagttgcaag cgctgcagct gctccagttg cccaaactgc tatcccagaa
      541 ggaactgtta tcggagacgg taaattgaaa atcaatcttg cccgtcttga cacacgacta
      601 cttcacggtc aggttgcaac tgcttggact ccagattcaa aagcaaatcg tatcatcgtt
      661 gcttcagata acgtggctaa agacgacctt cgtaaagaat tgattaaaca agcagctcca
      721 ggtaatgtca aggctaacgt ggttccaatt caaaaactga ttgagatttc aaaagaccca
      781 cgttttggag aaacacatgc ccttatcttg tttgaaacac ctcaagatgc ccttcgtgcc
      841 atcgaaggcg gcgtgccaat caagactctt aacgttggtt ctatggctca ctcaacaggt
      901 aaaacattgg tcaataccgt tttgtctatg gacaaagaag atgttgctac atttgaaaaa
      961 atgcgtgact tgggtgttga atttgatgtc cgtaaagtac caaatgattc taaaaaagat
     1021 ttgtttgact tgattaacaa agccaatgtc aaataagcca ttatttatga aaggatttta
     1081 aacatgtcta ttatttctat ggttttagta gtcgttgtag ccttctttgc aggtcttgaa
     1141 ggcatcctcg accagttcca atttcaccaa ccacttgtag cctgtaccct tattgggctt
     1201 gtaacaggtc acttggaagc agggattatc ctcggtggat cgcttcaaat gattgccctt
     1261 ggttggtcaa atatcggtgc tgctatcgct cctgatgctg cacttgcttc tgtcgctgct
     1321 gccattatca tggttcttgg tggtgacttt accaagactg gtatcggtgt tgcccaagcg
     1381 gttgctatcc ctcttgccgt agctggactt ttcttgacaa tgattgttcg tacaatttca
     1441 gttggtttgg ttcatactgc agatgctgcc gctaaaaaag gtgacttcgg cgctgtggag
     1501 cgtgcgcatt tcattgcgct acttttccaa ggacttcgta tcgcgcttcc tgcagctctt
     1561 ctccttatgg taccaactga aactgtacaa agtatcctta gtgccatgcc agactggctc
     1621 aaagatggta tggctatcgg tggtggtatg gtcgttgccg ttggttacgc catggttatc
     1681 aacatgatgg caactcgtga agtatggcca ttcttcgctc ttggtttcgt tctcgctgct
     1741 gtgtcagata ttactctaat cggattcggt gctatcggtg ttgctatcgc tcttatctac
     1801 cttcaccttt ctaaaactgg tggaaatggt ggcggaggag ccgcaacttc taacgaccca
     1861 atcggcgata tcctagaaga ctactaagat aagaaaggac tgaaaacatc atgactgaaa
     1921 aacttcaatt aactaaatca gatcgtaaaa aagtttggtg gcgttcaacc ttcttacaag
     1981 ggtcttggaa ctttgaacgg atgcaaaact tgggctgggc ttatacactc attccagcta
     2041 tcaaaaaact ctatactaaa aaagaagatc aaatcgctgc tcttgagcgt caccttgagt
     2101 tcttcaacac tcatccatac gtagctgctc cagtcatggg ggttactctt gcgcttgaag
     2161 aagaacgtgc taacggtgtg gaaatcgatg acgctgctat ccaaggggtt aaaatcggta
     2221 tgatgggacc tcttgctggt atcggtgacc cagtattctg gtttacagta cgcccaatcc
     2281 ttggatctct cggtgcttca cttgccctta ctggcaatat cttggggcca ctcctcttct
     2341 ttgttgcatg gaacttgatt cgtatgtcat tcttgtggta tgttcaagag attggataca
     2401 aggctggatc agaaatcact aaagatatgt ctggtggtat ccttcaagat atcactaaag
     2461 gagcttctat ccttgggatg ttcattcttg ctgtccttgt tcaacgctgg gtaaatatta
     2521 aatttgcttt cgatgtttct aaagttcaac tagatgaaaa ggcttatatc cattgggata
     2581 aattgccaga agggtctaaa ggtatccaag aagcattcgc acaagtagga caaggattgt
     2641 ctcaaactcc tgaaaaagtt actactttcc aacaaaactt ggatatgttg attcctggat
     2701 tatcaggact actccttact ttactttgca tgtacttact taagaaaaaa gtatctccaa
     2761 tcactattat ccttgccctc ttcgcagtgg gtattgtggc acatgttctt cacatcatgt
     2821 aatcaagcaa ctaaaaagga accaggttct aaaatctgat tccttttttc tatgctttta
     2881 ttcagccaag gctcccattg gatcccatgg tgcaagtacg attggttctg ctccataggc
     2941 agcttgttct tctgctgtca gcaattcctt acgaacaacg atttggtatg tgtattcgtc
     3001 catccaagcg tctgaggcaa caaagtaacc atctgtaccg accttgtctc cccatgagtt
     3061 ttcaaccttc cacttggttg atttaccatt ttcgtccaag tcaacacctg tcaagaccat
     3121 ggcgtgggtc atcaagcttt cgctatagtc caaacgtcca gccttgtctt gagtaagttt
     3181 aatgtccatg cttgattcaa agtcataaac atctgtcgca aggatgccag ccttacggtt
     3241 gctgagctgg ccgacatcag aaccaaacca aacagtctca cctgcttgca tttgggcaat
     3301 cgccaattct ttcaagcgct ccattggaac gttgatgtag cgaactgcac ggctaccaac
     3361 aacattcccc aacatctcaa ctgtgtaaga ttttccgtaa ggtttatcag cagttggagc
     3421 attgataaca gaaacgtagt cttctaaagg aagattgaca tatttcttgt aaaactcttg
     3481 tggtgtgatt cctttttcac ttttgtagtt gttatcttta tcgcgataag caaagtcaaa
     3541 cttgcgtggt ggaagtccta atgacatagc aagaaagtta aagatttctt gcaagaggtc
     3601 ttctttctta gtttgaacag tcgcttgatc tgcaccagaa acaagcaaat cacgcaagat
     3661 ttgagcatct tgacgaagca atttattaag gatcgcattt agctcacgac tgctgctaga
     3721 tgaaacagac tcaggataaa ctgacttagg cacgacaccg tatttttcaa agagggaaac
     3781 gaccatatcc cattgaccgc catcttgttg aggtgtttgg agtaagaagc taaccttgcg
     3841 gctagtcaat tcttggtctg aagtcgcaat gacttgctcc aagaaccagt ttgatttctc
     3901 atacttatcc cagaagaaag tgtgggcttg tgacaactca aagttctcca atttgtattg
     3961 cgagatgagt ttgtggcgga aggtgttgag agccgcaaac atccagcaac gaccagacgc
     4021 tttctggtta gtgaccttgt ccttggttaa atccaatgag aaaacaggtg tgttgtctac
     4081 atggctttgg cgacattcca gagctgcaaa aattccgttg tggctggcag cattttcaat
     4141 cgctttgtat tttacatttg cttcatagtt ggcaaatagt ttattagtaa atgattcttg
     4201 aatcgcgttc atagattcct ccttttattc tacagtctat tataactctt ttcacaaagg
     4261 aagcaactaa aaaacataaa aggtaaggac attctccctc acctttttcg aatttatact
     4321 cttcgaaaat caaattcaaa ccacgtcaac gtcgccttgc cgtactcaag tacagcctgc
     4381 ggctagtttc ctagtttgct ctttgatttt cattgagtat taaactaaat taaataatat
     4441 tagcgcggag aatttctaat tcttccttgg tcaagcgacg ccattcccct cgttccaggt
     4501 tctcatctaa tactaaagtt cccatagtca atcgttgcaa gtccaccact tccttgccac
     4561 agtagcccac catacgcttg atctgatgaa acttcccttc tgcaatggtc acacggattt
     4621 ggctttgatt cttttctgta tctatggata caagctccag tatagcgggt tgacaggtaa
     4681 agtctttgag aggaataccc tcagcaaatg tctccacatc ttcttgggtc atgattccct
     4741 tgacttgtgc cagataagtc ttgtccacat gacgcttggg cgaaagaaga acatgagcca
     4801 gctgaccatc attggtcaag agcaaaagac catgcgtgtc aatatccaag cgtcctactg
     4861 ggaaaacttc cttactccgc gccaagtcat ccaacaagtc cagaacggtt ctgtgcttgg
     4921 gatcctcagt cgctgagata actcctttgg gcttgttcat catgtagtag acaaactctt
     4981 catactccaa cacttgccca tcaaagcgaa tctcatctat tttttcatca atctgcaatt
     5041 tagctgattt ttctttttta ccatttacag tcacgcgccc agccttgagc aagtttttga
     5101 cctcagtccg acttcccacc gcacaggcaa ctaaaaattt atctaatctc atagaactat
     5161 tatatcatat caaaaggagg ctggtacaat gaccaacctc cttttcgttt catactcttc
     5221 aaaaatctct tcaaaccgcg tcaacgtcgc cttgccgtat atatgttact gacttcgtca
     5281 gttctatctg caacctcaaa acagtgtttt tagctgactt cgtcagttct atctgcaacc
     5341 tcaaaacagt gtttttagct gacttcgtca gttctatctg caacctcaaa gcagtgcttt
     5401 gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta tcagatttag
     5461 gaaattaact tcctcgtctc caaaaaatag ctaagacaat catggcacct aaaacagctg
     5521 ggataatagc tgttcctgat aaaactggcc cccaagttcc aaagagcaag tgacctagaa
     5581 aggctccgat ccaaccgaga aacatttttc caaaacatcc cattcgctct ccacgattgg
     5641 tcatagcacc tgctaaaaat cccactagga gaccaacgaa catacttcct aacatattat
     5701 ctccttaatt tgcccaattc ccattacgga aaagaggtac ccgcgttcca tcctcacgaa
     5761 taccatcgat atccatttgg ttagaaccaa tcataaagtc tacgtgaaca tctgaacggt
     5821 taagccctgc agcttcaagc tcctcttcgc tcatctccgc tccatcaaca aggctagtcg
     5881 cataggctgc accgatagcc aagtggtttg acgcattttc atcgaaaagg gtgttaaaga
     5941 aggtaatgcc tgactgagaa attggacttg gatctggtac caaggcacat tcacccaagg
     6001 cacgcgcacc cgcattttca aagacaaggt ctttcataac ctgatcaccc ttctcagcag
     6061 tgatatctac gatttgtcca tccttaaaga tcaccttaat gccttcaatg atatttccgt
     6121 tgtagctaag cggttttgta gaagtgacat aaccatctgc acgacggaag tcaggcgctg
     6181 tgaagacctc ttctgtcggc atatttggca agaatccttc gccctgtgca ttgacagcac
     6241 cagctgattc ccaaacgtgg ttctttggca aaccaagtgt taaatctgtt cctggcgctg
     6301 tgtagtgaag ggctgaaaat tgctccttat taagcatatc ggccttgctc ttgagaatgg
     6361 ctgcatgctc ttcccaggcc ttaacaggat ctgcttcgta gacacggcaa gttttgaaga
     6421 tttggtccca aaggagatcg actgcttctt cgtcgctcgc agcatttggg aagactttct
     6481 tagcccactc aagtccagca gcggctgcta cagtccagct aaccttgtta gattgagttg
     6541 cgattcgcat tggcttcatg gcaagtccca tagctttagc agaagctgaa agcttgtcag
     6601 cgtccactcc gttcaaggca cctggatcag atgaacgaac tccaagacgg ctagccttgt
     6661 tctccaagag atagttcatc tcagcaatct tgtattctgg cacattgtcc aaacgctcca
     6721 tcggggcatg gaggaatttc tcacggttaa tcacatcatc tgtccactga acgatgacct
     6781 catgcgcacc caaggcataa gcttctttca cgattagatg tgccaattca cgttgctcca
     6841 catcaataga gagagccaaa gtgtgaccag gttgcacgtt aattccgttc gcaaccaaca
     6901 atttcgcata tttttctaga ttttctttaa aatttggtaa aaccatcctg ttttctcttt
     6961 tctattttta tttttctttc aaagcagaaa agattcctgc taaagcaata gcacctgaca
     7021 agagtgctgt cgataaaaga attgtacgat cagcaagttc taattgatat tcaaatacct
     7081 tcttagccgg cttatcttcc gcaaatattc ttagtttcat gagaaccccc ttaaaataga
     7141 ttaaaataaa tcactgtgac tgcctgtcct cagcaaattt aaaatcaatt ccgacttatc
     7201 tactttataa accaaaagcc aatctggctg ggtatggcat tcacgaactc cttgaaaatg
     7261 cttggatgcc gtcaatgaat gatcacgata tctggcagga tgttcttttt cttgaaccag
     7321 aaaattcaaa acttcttcta ataattctgc cttcaaacca cgcttcatag ccaacttaaa
     7381 atctttttta aactgtttat gataacgaat cttaagcacg taagtcctcc atcaaatctg
     7441 agactgattc aaaagactgg ctcatattac gattttggtc taaatccgtt aacacttgga
     7501 gcaacttccg attttcgtct agtctaacat caaaaggtaa tccctgatat tgaattgcct
     7561 gacgaaggaa aatattaata gctgttgtca tatccattcc cagattacta aacacctgtt
     7621 gggcctgctc cttaacctca ctatccagac ggatgctcat actcatcttt gacatactct
     7681 caccctcttt ccatagacta ttttaacaaa aaagaaagct aatgtaaatc tattggatat
     7741 acgttagcct cttctaatag attattaagc aattttttaa aacaactcat caaacaaact
     7801 caactggtta tcctctggca tatttccaag aatacccatc tcatccatct tttcaaccaa
     7861 ggttgatgag agtccaccac gcttgcgtag ttctgtttta gagaggaatt ctccctcttc
     7921 acgcgcccgc accagttgct tggcaacgtt ctctcccaga ccatccattg ctacaaatgg
     7981 tgggataagg gtatccccgt cgatgaggaa ctctgtcgcc tgactacggt agagatctaa
     8041 tttgccaaac ttgaaacctc gttcccacat ctcattgaca atctcaagag ttgtatagag
     8101 atcgatttcc acattagagg cttcattgtt cttccgtttt tcagagattt cttccattct
     8161 gcgcttgatg gcctccaagc ccgcacccat ggtcttgata tcaaaagcct tagcacgaat
     8221 ggagaagtaa gcacagtagt aataaatagg atggtgaacc ttgaagtaag ctacacgcaa
     8281 ggccatcata acgtaggctg ccgcatgggc cttagggaac atgtacttaa ttttcccaca
     8341 ggattcgata taccactctg gcaccttatt agccttcatg gcttcgatat agccatttct
     8401 ctcctcttct gaaatcttta gccacaaacc cttacgtacc cgttccataa tggtaaaggc
     8461 catcttaggt tccagacccg catgcatgag gtaaaccatg atgtcgtccc gacaaccgat
     8521 aacagtcgat aggtccgcta ttccttgctt aatcagatcc tgagcattcc ccaaccaaac
     8581 gtcagtaccg tgggacagac cagacagctg aagcaattcc gcaaaggttg tcggatgggt
     8641 ttcgtctacc attccacgta cgaaatttgt tccaaactct ggaatcccca acatacccgt
     8701 aggcgttcca atttgttcag gtgttacccc tagcacatca gtcccagaaa agagtgccat
     8761 cacgccttcg tcatccatag gaattttatt agggtcaata ccagacaaat cctgaagttt
     8821 tcgaatcatg gtcggatcat catgtcccag tacatcgagt ttgaggacgt tctcatcgat
     8881 atcgtggaag ttaaagtgag tggtctgcca ttcagccgtg acatcatctg ctggatactg
     8941 gacaggcgta aaatcgtaga cattcatgta gttcggaata acaacgattc cccccgggtg
     9001 ttggcctgtt gtccgcttga cacccgccgc tccttgagcg aggcgttcta cttctgcatc
     9061 acgataaaac ttgccataat ctcgctcgta acccttgaca aatccatagg cagtcttggc
     9121 agctaccgta ccaaccgttc ccgcacggaa ggcatattct tcaccaaaga tatcacgcac
     9181 atccaagtgg gcgctaggct gatcttctcc cgagaagttc aagtcaatat caggaacctt
     9241 atccccatca aaaccaagga aggtctcaaa cggaatatcc tgtccgtttt tactgagttt
     9301 gtgaccacag tttggacagt ccttatgggg catatcaaat cctgaaccgt acgaaccatc
     9361 tgtgataaac tcactgtact gacactgacc acagacatag tgaggagaga gaggattgac
     9421 ctccgtaatc ccaatcatgg tcgcaacgaa actagatccg acagacccac gagaaccaac
     9481 caaataaccc cgttcattag aacgttgcac cagcatctgc gatgccagat aaatcacagc
     9541 aaatccattc cccagtatgg atgttaattc tttttcaatc cgcaaatcaa caatatctgg
     9601 cagcggattt ccataaatct caaaagcttt cttataggtc aactcagcaa ctgtttcttc
     9661 agccttgttg atgaaaggcg tatacaagtc acccttaacg acttcaacgg gttcaaatat
     9721 ttctgccaag gcattagtgt tttcaataac cagtttacga gccagttcct ctcccaaaaa
     9781 ggcaaattca tccaacatct cattagtcgt tcgaaaatga gcctttggaa gtggcgctgg
     9841 ttgggcatgt tcaccatgac cgatagttcg gttaatcatc gcaccctgtc ccaaactacg
     9901 gacgataatt tcacgataaa tctcttcttc cggttcgata tagtgaacat ttcccgtagc
     9961 cagaacaggc ttgccaaggc gatctccaac ctctatcaaa ctcttgataa tggtctggag
    10021 ttcctccata tccttgacct gctctttggc aatcaagggc gcatagatag ccggtggcat
    10081 gacctcgata aagtcataat acttggccac ctcaaccgcc gcatccacac cttgagaaac
    10141 gaccacgtca aaaacttcac cctctgaaca ggctgaacct aaaatcaagc cctctcgatg
    10201 ggcatctaga accgttctcg gaatccgtgg cactccttca aaatacttgg tattagacaa
    10261 ggaaaccagc ttaaagatat tttttagacc tacctgattc ttgacataga tggtcgcatg
    10321 cttgatccga gcttttttgt aagaatctgg actgattaga tcaatgttga gtctagctaa
    10381 atcggtcaca ccatgttttt ctgctacctc tttgataaag atgaaaagca gacgaccagt
    10441 cgcttccgca tcgtagttgg ccatgtggtg atgttccaag gccacaccaa aacgcttggt
    10501 caaaggcccc aaaccatggc gtttatactc aggatagagg tttctagcaa actccagcgt
    10561 atcaataact ggctgactaa tctttggaag accatgacgc tcataattag cattcataaa
    10621 gccaacgtca aaggcagcat tgtgggcaac taggaccgta tccttgcaaa attcttggaa
    10681 ttcttgcaaa acttgttcta gtggtttggc atttttgaca tgatcatctg taattccagt
    10741 taactctgta gtaaaagctg acaagggatg cccaggattg ataaattcat caaattcagc
    10801 aataacattc cccttgtaca tcttagaggc cgcaacctga atcaagtcat tatagatagc
    10861 tgaaagtccc gtcgtttcca cgtcaaagac cacgtaggtt gcttctgata agtccatctc
    10921 cacttcgtta tagacgatag ggacacggtc ctccacgata ttggcttcta tcccatagat
    10981 cagctggatt cccgctttct tagccgcctt atagccatgt ggaaaggact ggacattccc
    11041 atggtctgtg atagcaaccg ccttgtgtcc ccacttagca gctgttgcaa caatctcttc
    11101 gacctctggc aaagcatcca tagtcgacat gttagtatga gcatgaaact caacccgacg
    11161 ctcaccttct ggcatcaaat ccttccgctc atagtgaaca acttcctgca gatcctgtac
    11221 gttcatagtc aaatcgcgtg tgaagttatt catctccaca ttccctcgaa ctcggagcca
    11281 agaattcttc ttgatgaggt caaacttctg ggcctcttcc tcgtttttaa cccacttttg
    11341 catagaaaaa cttgaagtat agtccgtcat tttaaagttg attaaaacac gacctgttct
    11401 agtcactttt tgctccacat caaaaacaac cccttcaaat accagacgat tttcctctgt
    11461 cgtcacttcg atcataggag taatctccgc cttatccagc ttgggtttag ctgcagcttt
    11521 tttcgcttga aaatcaaaga ctggtttctc ttccgctgga ggaggtgcca tctgctccag
    11581 ttgttccata gcacggagcg cttcctcatt ggcagcttga acaatctgct cattttcagc
    11641 atgaaaggcc tcttcctgct cttgggtcag gacatcattc ttctcgactt gacagttaaa
    11701 agttggaaaa ccaaactttt caagttgttt ggctaaatta ggaagatgat tcttcttaaa
    11761 atgttcctta tcaatcgctt cagatccttc aataaatagc tgattaccct cagcacgaac
    11821 ttgcaaattt tgataaaggg acttaaaacc ttgactagca catggacctt cagagaaagc
    11881 ctccctatag taggactgca agagctgatt tgaaaattct tgagaccgag ccttaatttc
    11941 aaaaacagct ttattgcctg tcttagaaaa ttcttcgctc aaacctttct ttaattctaa
    12001 aaagatttca atcggtaaaa tattagaaaa tacgaaatga aactcccata ccttactaat
    12061 tttatgaacc acaactcgct caatattggc ctgtgctaaa gcaggagcct gtctcatttc
    12121 agcaggcatc cccaattgat tcatcaaaat ttcaaaacta tttgacattc attttcctca
    12181 cattattctt ctactatttt accatattta gaggtatttt ctaaagacaa aaggaagcca
    12241 ctaagtgact tccttctaga gtgaggacgg attagtcttc acctttattt ttcttaataa
    12301 tttcttcttg tactgactta ggtacatctt cgtagtggtc aaataccatc atgaatgtac
    12361 cacgtccttg agatgcagaa cgaagaactg ttgcgtaacc gaacatttca gcaagtggaa
    12421 cgtaagcacg aacgatttgg ctgttaccgt gtgcttccat accatctaca cgtccacgac
    12481 gagcagttac gtgacccata acatcaccaa ggttttcttc tggaacagtg attgttacaa
    12541 gcatcattgg ttcaaggata gctggttgtg ctgatttagc agcttcttta agggaaagtg
    12601 aagccgcaat cttgaaggca gtttcagatg agtcgacatc gtgatatgaa ccatcataaa
    12661 gcttagcttt aacgtcaacc attgggtaac ctgcaagaac accgttagcc atagattcta
    12721 ccaaaccttt ttcaaccgct gggataaatt cacgaggaac cacaccaccg acgattgcgt
    12781 tttcgaattc gaatccttta ccttcttcgt ttggagtaaa ttcaatccac acatcaccga
    12841 attgaccttt accaccagac tgacgtttga agaatccacg tgcttgagta gaagcgcgga
    12901 atgtttcacg gtaagatact tgaggagcac ctacgttcgc ttcaactttg aactcacgac
    12961 gcatacgatc aacaaggacg tcaaggtgaa gttcacccat acctgagata actgtttcac
    13021 cagtttcaac gtttgtttca acgcggaatg ttggatcttc ttcagccaat ttttgaaggg
    13081 cgatacccat cttgtcttgg tcagctttag attttggctc aaccatcaat tggataactg
    13141 gttctggaac gttgattgac tcaaggatga ttttagcttt ttcatctgtc aatgagtcac
    13201 cagttgtagt atctttcaaa ccaacggcag cagcgatatc acctgagtaa acagtgtcga
    13261 tttcttgacg gctgttagcg tgcatttgaa ggatacgtcc gatacgttca cgtttacctt
    13321 tagaagtatt caatacgtat gaacctgatt gaagaacacc tgagtaaaca cggaagaatg
    13381 tcaaacgacc tacgaatggg tcagtcatga tcttgaaggc aagagctgca aatggctctt
    13441 cgtcagatgc tggacgaatt tcttcagcgt ctgtatctgg gttaatacct ttgattgctg
    13501 ggatgtcaag tgggcttgga aggtagtcga taaccgcatc aagcatcaat tgaacacctt
    13561 tgtttttgaa ggctgaacca cacaatactg ggaagaattc aacgttgata gtcgctttac
    13621 ggataccagc tttcaattct tcgttagtga tttcttcacc ttcgaggtat ttcatcatca
    13681 attcttcgtc agtttcagca actgcttcaa tcaatttttc acggtattct tgagcttggt
    13741 caaggtattc agctgggatg tcttcttcaa ggatatccgt accaaggtcg ttagtataga
    13801 tttcagcttt catcttgatc aagtcaatga taccacggaa gtcatcttca gaaccgattg
    13861 gcaattggat tgggtgtgca tttgcttgaa gacgatcgtg aagtgtgctt acagagtaaa
    13921 ggaagtcagc accgattttg tccattttgt tggcaaatac gatacgtgga actccgtact
    13981 cagtcgcttg acgccaaact gtttcagttt gaggctcaac acctgattgt gagtcaagaa
    14041 cggtaaccgc accatccaat acacgaagag aacgttgtac ttcgattgtg aagtccacgt
    14101 gtcctggtgt gtcgatgatg tttacgcggt ggttgttcca ttgagctgtt gtcgcagcag
    14161 atgtgatcgt gataccacgt tcttgctctt gctccatcca gtccatttgt gacgcacctt
    14221 cgtgagtttc accgattttg tggattttac cagtgtagta aagaatacgc tcagtagttg
    14281 ttgttttacc ggcatcgacg tgagccatga taccgatatt acgagttttt tcaagtgaaa
    14341 attcgcgtgc catgaggttt gtttctccta tttatttttg atttctattc tattataaca
    14401 cgattttaat aaaaacggat aggcaggacc tacccgttct caatgttttc atgctattgt
    14461 tggtttcaac ttacgagatg gtaagctgag ttatagctaa tactaatcga tttagctaat
    14521 ttgaacccgg gctaaagtta gttagccgat gtgagctgga acgagatgcc gcgtgaaaaa
    14581 gataaaactc cttgtattcg tcgaatactg cgtcagtttc ctattttcac cttgcatcct
    14641 taccgttcct agcatcatga tttagttgag ctcaagctaa aagtctggag aaaagatgaa
    14701 tctcattggt tgcaaccgca acccgcttcg attccctatt ttctctggga ctttcttaac
    14761 gctttcgcat cctatcttac caacggaagt gtgcgaatgc acggttagct tcagccatac
    14821 ggtgagtgtc ttcacgtttc ttaacagctg caccagtgtt gttagtagca tccaagattt
    14881 cttttgcaag acggtcttgc attgtgtgtt caccacgaag acgagcgatt gttaccaacc
    14941 aacgaagtcc aagtgttgta cgacgttctg gacgaacttc aactgggact tggtagttag
    15001 aaccaccaac acgacgtgca cgtacttcaa gtacaggcat gatgttttcc atagctgttt
    15061 caaatacttc aagtgcatcg ttgccagtag cttctttgat ttgctcaaaa gcaccgtaaa
    15121 cgattgaagc agcagtacca cgtttaccat caagcataac gcggttgata agacgagtaa
    15181 ctagttgtga attgtatagc ggatctggca atacgtcacg ttttggagct ctatttttac
    15241 gactcatttc tctttatccc cttcccttat gcttttggac gtttagtacc gtatttagaa
    15301 cggccttgtt tacgatcgtt aacacctgca gtatcaagtg caccacggac gatatggtaa
    15361 cgtacccctg gaaggtcttt tacacgtcca ccgcgaagaa gcaccacgct gtgctcttgc
    15421 aagttgtgtc cgatacctgg gatgtaggca gtaacttcga taaggttgct caaacgtaca
    15481 cgagcgaatt tacgaagggc tgagttaggt tttttaggtg tcattgttcc aacacgagtt
    15541 gcaacaccac gtttttgtgg tgaagaaacg tttgtttgaa cttttttatg actattgtaa
    15601 ccaacgttca aagctggtga tttagatttt tctacttttg atttacgcgg tttgcgaacc
    15661 aattggttaa ttgtaggcat ctacattctc ctgtattttt ttatttttgg tgatgataca
    15721 cttggtgaca gatatcatct gtgtgtactt ttgcaacatt tgtcagcacg tccctgtaca
    15781 ctcttgagag accaaaagta aaaagtaccg tctattattg taacaaaatt ttcccttgct
    15841 tgtcaagata tttttctttt ttattggtaa tgttagagat caatttctga ataaaaatag
    15901 ctgggaacac atcatcttcc taataatacg gcttgactta tgtgacattt ttatctccgt
    15961 catttatact gatatataaa atagtacaga aaacttctca aaagtaagaa tttttttcac
    16021 aaatcaaaga aaacgcttgc atattgtttt actacatgct atactgatat agaaatttat
    16081 tgattggaga atcattatga gaaaaacacc atctcacact gagaaaaaaa tggtctacag
    16141 catccgttcc ctcaaaaatg ggactggttc tgtccttatc ggcgcaagcc ttgtcttgct
    16201 tgccatggct acaccaacta tctcatccga cgaaagtaca ccaaccacta acgaacccaa
    16261 caacagaaat acaaccaccc ttgcccaacc tcttactgat acagcagctg gctctggtaa
    16321 gaacgaaagt ggtatttctt cacctggaaa tgcaaacgct tccctagaga aaacagaaga
    16381 aaaacctgca acagagccac caactcctgc tgcaagccca gccgatccag caccacaaac
    16441 tggacaagat cgttcaagtg agccaactac ttctactagt ccagtaacaa ctgaaactaa
    16501 ggcagaagag cccatcgaag ataactactt ccgtatccat gtcaaaaaac ttcctgaaga
    16561 aaacaaggat gctcaaggac tatggacttg ggacgatgtt gaaaaaccat ctgaaaactg
    16621 gccaaacgga gctttgtcct tcaaggatgc caagaaagat gactacggct attacctaga
    16681 tgtcaaatta aagggagaac aagccaagaa aattagcttc ctcatcaaca atacagctgg
    16741 aaaaaatcta accggcgata aatctgtaga aaaactagtt ccaaaaatga acgaagcttg
    16801 gttagaccaa gattacaagg ttttctctta cgagccacag cctgcaggaa ctgttcgcgt
    16861 caactactac cgcacagatg gcaactatga caagaaatct ctctggtact ggggagatgt
    16921 gaaaaatcca agtagcgctc aatggcctga cggaacagac tttacggcta caggcaaata
    16981 tggccgctat atcgacattc ctcttaatga agccgcaaga gaatttggat ttttattact
    17041 agatgagagc aaacaaggag acgacgtgaa aatccgtaaa gaaaattata agttcacaga
    17101 tttgaaaaat catagccaaa ttttcctaaa agacgatgat gaatcgattt acacaaatcc
    17161 atactatgtc catgatatcc gtatgacagg agcccaacac gtaggcactt ctagcattga
    17221 aagtagcttt tcaacacttg tcggtgctaa aaaagaagat atcctcaaac actccaacat
    17281 cactaatcac ctaggaaaca aggtaactat taccgatgtt gcaatcgatg aagctggtaa
    17341 gaaagtgacc tacagcggag atttctctga cacaaaacat ccttatactg ttagctacaa
    17401 ttccgaccaa ttcactacca aaacaagctg gcacctgaaa gatgagacat acagctatga
    17461 tggcaaactg ggagctgacc taaaagaaga aggaaaacaa gttgatttga ccctttggtc
    17521 accaagtgct gataaggttt ctgttgttgt ctacgacaag aatgaccctg acaaagtagt
    17581 tggaactgtc gctctcgaaa aaggggaaag aggaacttgg aaacaaactc tagacagcac
    17641 aaacaaactc ggaatcacag atttcactgg ctactattat caataccaaa tcgagcgtca
    17701 aggtaaaact gttcttgcac tcgatcctta cgctaaatct cttgctgctt ggaatagcga
    17761 cgatgccaag attgacgatg cccataaagt ggctaaagcc gcctttgtag atccagctaa
    17821 actcggacct caagacttga cttatggtaa gattcacaat ttcaagactc gtgaagacgc
    17881 cgttatctac gaagctcatg tgcgtgactt cacttcagat cctgccattg caaaagactt
    17941 gaccaaacca tttgggactt ttgaagcctt cattgaaaaa ctagactatc tcaaagactt
    18001 gggtgtaacc catatccagc tccttccagt cttgtcttac tactttgtca atgaattgaa
    18061 aaaccatgaa cgcttgtctg actatgcttc aagcaacagc aactacaact ggggatatga
    18121 ccctcaaaac tacttctcct tgactggtat gtactcaagc gatcctaaga atccagaaaa
    18181 acgaatcgca gaatttaaaa acctcatcaa cgaaatccac aaacgtggta tgggagctat
    18241 cctagatgtc gtttataacc acacagccaa agtcgatatc tttgaagacc tagagccaaa
    18301 ctactaccac tttatggatg ccgatggcac acctcgaact agctttggtg gtggacgctt
    18361 ggggacaacc caccatatga ccaaacggct cctagttgac tctatcaaat acctagttga
    18421 tacctacaaa gtggatggct tccgcttcga tatgatggga gaccatgacg ccgcttctat
    18481 cgaagaagct tacaaggctg cacgcgccct caatccaaac ctcatcatgc ttggtgaagg
    18541 ttggagaacc tatgccggtg atgaaaacat gcctactaaa gctgctgacc aagattggat
    18601 gaaacatacc gatactgtcg ctgtcttttc agatgacatc cgtaacaacc tcaaatctgg
    18661 ttatccaaac gaaggtcaac ctgcctttat cacaggtggc aagcgtgatg tcaacaccat
    18721 ctttaaaaat ctcattgctc aaccaactaa ctttgaagct gacagccctg gagatgtcat
    18781 ccaatacata gcagcccatg ataacttgac cctctttgac atcattgccc agtctatcaa
    18841 aaaagaccca agcaaggctg agaactatgc tgaaatccac cgtcgtttac gacttggaaa
    18901 tctcatggtc ttgacagctc aaggaactcc atttatccac tccggtcagg aatatggacg
    18961 tactaaacaa ttccgtgacc cagcctacaa gactccagta gcagaggata aggttccaaa
    19021 caaatctcac ttgttgcgtg ataaggacgg caacccattt gactatcctt acttcatcca
    19081 tgattcttac gattctagcg acgcagtcaa caagtttgac tggactaagg ctacagatgg
    19141 taaagcttat cctgaaaatg tcaagagccg tgactatatg aaaggtttga ttgcccttcg
    19201 tcaatctaca gatgccttcc gacttaagag tctccaagat atcaaagacc gtgtccacct
    19261 catcactgtc ccaggccaaa atggtgtgga aaaagaggat gtagtgattg gctaccaaat
    19321 cactgctcca aacggcgata tctacgcagt ctttgtcaat gcggatgaaa aagctcgcga
    19381 atttaatttg ggaactgcct ttgcacatct aagaaatgcg gaagttttgg cagatgaaaa
    19441 ccaagcagga tcagtcaaaa ttgccaaccc gaaaggactt gaatggactg aaaaaggctt
    19501 gaaattgaat gcccttacag ctactgttct tcgagtctct caaaatggaa ctagccatga
    19561 gtcaactgca gaagagaaac cagactcaac cccttccaag cctgaacatc aaaatgaagc
    19621 ttctcaccct gcacatcaag acccagctcc agaagctaga cctgattcta ctaaaccaga
    19681 tgccaaagta gctgatgcgg aaaataaacc tagccaagct acagctgatt cacaagctga
    19741 acaaccagca caagaagcac aagaagcatc tgtaaaagaa gcggttcgaa acgaatcggt
    19801 agaaaactct agcaaggaaa atatacctgc aaccccagat aaacaagctg aacttccaaa
    19861 tacaggaatc aaaaacgaaa acaaactcct atttgcagga atcagcctcc ttgcgctcct
    19921 tggtctcggt ttcttactaa aaaataaaaa agagaactaa actagccctc ctatagaaaa
    19981 atcccccaag cattatagct cgggggatta attttcgtac aatatttgtt gtcctaataa
    20041 acttgattag gattttttat taagcctctt tcatagcaaa ataagctcgt actttgggtg
    20101 caacttgtgt tccgaagagt tcaatagctc tcagaacctg gtcatgaggc atagaaccaa
    20161 gcggtagatg aagcatgaag cggtccaatc ctaaatcctc tatcatgcga atcaattttt
    20221 cggccacctg atctggattg ccaacaaaca tggcgccatt tggccctacc tgctccaaat
    20281 attgctcata acgcaattcc tgccagtgcg gacggtcttt ggaaatagca tccaccactt
    20341 gcttagtcgg atggaaataa tctttcaccg cctgctcacc atcttccgca atccaccccc
    20401 aagaatgggc tcccactttc aagtctttgt cagcatgacc cgcttcgctt ccaatctcac
    20461 gataagcctg aatcaacttt ttaaaataac gtggattacc accaataata gcatatacaa
    20521 tcggtagacc agcctgagca atcttcactg ttgattcgac atgaccacct gtagctatcc
    20581 acaagggcaa tttgtcctga actggacgag gataaacttc tttaccagca atcgtttgag
    20641 tcaatcgacc ttgccagtct aacttggtct tttcattgac taactgaagc aagtctaatt
    20701 tctcatcaaa aagagagtcg tagtctttca agtcataacc aaacagaggg aaagattccg
    20761 tgaaagagcc ccttccagcc ataatctccg ctcgtccatt tgacaaagca tcgatagtgg
    20821 catactgttg gaacaaacga atcgggtcca tgcttgacag aatgctgact gcactggtca
    20881 aacggatttt cttggtattg actgccccag cggccagaac aatctctggg gctgatactg
    20941 caaaatccgc ccgatggtgc tcaccaatcc catatacatc caaaccaacc ttgtcagcca
    21001 gctcaatctc tgccaccaac tggcgaatgc gttcagcatg actgtaagtt tgtccagtcc
    21061 cttcaagctc cgttatttcc ccaaatgttg aaattcccaa ttctaccatt gtgattctcc
    21121 ttatctatct ctgtacttca atttgaaaaa ttattctaat actcaatgaa aatcaaagag
    21181 caaactagga agctagctgc aggctgctca aaacagtgtt ttgaggttgt ggatagaact
    21241 gacgaagtca gtaaccatac ctacggcaag gcgacgttga cgtggtttga agagattttc
    21301 gaagagtata acacgaatct tgagtacaag caaccaattt gctcacaaga aaaaggccta
    21361 gataactaga cttttttagc ttattctacc gttactgact tggcaaggtt acgtggtttg
    21421 tccacatcga ggccacggtg gagggttgca aagtaagcga ctaattgcgt tggtacgacc
    21481 attgaaattg gtgagaggta tggatgtacg gtcgtaagga cgatatcgtc ggtatctttg
    21541 gctacattct cttctgcgat agtgaggact ttggcaccac gggctgcgac ctcttggata
    21601 tttccacgag tatgattggc aagaactgga tctgacaaga gagccaaaac aggcgttcct
    21661 tcttcaatca aggcaatggt tccgtgcttg agttctcctg cagcaaagcc ttcacactgg
    21721 atataagaaa tctctttgag tttgagactt gcttccatgg ctacgtagta atcttgacca
    21781 cgtccgatgt aaaaggcgtt acgagttgtt tcaagaagtt cacgaacctt ggcttcaatg
    21841 gtttctttct ctgaaagagt tgattcgata gactgagcta cgattgacaa ttcatgaacc
    21901 aggtcaaagg cttgcgcttt agcattacca tttgcttctc cgactgcttt tgcaaggaag
    21961 gcaagggctg cgatttgcgc tgtataggct ttagttgatg ccacggcaat ttcaggacct
    22021 gcgtgaagga gcatggtata gttggcttca cgtgagaggg ttgaacctgg aacgtttgtc
    22081 actgttaagc ttggaattcc catttcatta gccttgacca aaacttgacg actatccgct
    22141 gtttcaccag attggctgat aaagatgaag agtggtttct tgctgagaag tggcataccg
    22201 tagccccact cagatgagat tccaagttca actggtgtat ctgtcaattc ttccaacatt
    22261 ttcttagaag caaatcctgc atggtaagat gttccagctg caaggatgta gatgcggtct
    22321 gcgtcttgaa cagccttaat gatatctggg tctacgacaa cttgaccagc ctcatctgtg
    22381 taggcttgga tgagtttccg cataacagtt ggttgctcgt caatttcctt gagcatgtag
    22441 taagggtaag ttcccttacc gatatctgac aagtcaagtt cagcagtgta gctagcacgc
    22501 tcacgacgat ttccatcata gtcttgaact tccacactat cagccttgac gattaccaac
    22561 tcttggtcat ggatttccat gtattggtta gtttcacgaa tcatagccat ggcgtctgag
    22621 cagaccatgt tatagccttc tccaagacca atcaaaagtg gtgatttatt tttagctacg
    22681 tagatgactt caggatcttg tgagtcaacc aaggcaaagg cataagaacc acggatgatg
    22741 tgaagggctt ttttgaaggc ttcaagaact gagagccctt cttcttccgc aaattttcca
    22801 atcaaatgaa cggctatttc agtatctgtc tgccccttga agtggtgacc tgcaaggtat
    22861 tcttccttga tttcaagata gttctcaatc accccattat gcaccaagac aaaacgttct
    22921 gtctcagagc ggtgtgggtg agcattgtcc tcagttggtt ttccgtgagt agcccaacga
    22981 gtatgtccga taccagttgt tccctcaaca ccagctgtct tggcagacaa ttctgcaata
    23041 cgaccaacag ccttcaccaa atggttatca gcaccatcta ggacaaaaat tcccgcagaa
    23101 tcatagccac ggtattcaag cttttcaagc ccttgaatca aaatatcagt tgcatttgtg
    23161 tttccaacaa caccaacaat tccacacata gtatatacga cacaggcaag ctgtgctttc
    23221 tccttaaaat tggtatagtc taattcatct tttatagaat cagcaaaaac agtatatact
    23281 tgtttctttc acttgtcaag agtaaaaatt ggtatagttc aaattaagct cctgtaagca
    23341 taaaaactct gaccgattgg gataatcagt cagagtcctt tttaaaatcc attattatcg
    23401 cttaattctt tgaaccagtg gcctgatttc ttcagacgac gttcttgcgt ttccaagtct
    23461 aattcgacca aaccatagcg atttttatag ctgttgagcc atgaccagca gtcaataaag
    23521 gtccaaatca agtagccctt acagttggca ccatcttcaa tggcacggtg aagttcacga
    23581 agatgacctt ttacaaagtc aatacggtaa tcatcttgaa tcattccatc ttgacggaat
    23641 ttttcttccc cttcaacacc cataccattc tcagtcaaca tccactcaat attgccataa
    23701 ttttccttga tattttgggc gatgtcataa atcccttgct cataaatctc ccaaccacgg
    23761 tgagaattga ttttacgtcc aggcatcaca taaggctcgt aaaaatgttc tggtaagagt
    23821 ggactatctg gatgcttagc aaatcgagga gccataacac gcaaaggttg atagtagttc
    23881 acaccaagga agtccaccgt attatcacga atgagttcca actcttcctc tgtagcatca
    23941 ggtaaaagac cgtgttcatg caagatttct accaactcct gtggataagt ccccaagaca
    24001 gatggatcta agaaagattg ggcctgaaaa agggccgcaa tacgagctgc cttgacatca
    24061 gcaggatgct ggctacgtgg ataagccggt gtcaagttga ggacaatccc aatcttggaa
    24121 tcaggcaaaa gttcatggca agccttaaca gcccggctgc tggccaattg tgtatgatag
    24181 gctaccttaa cagctgcctc tgcatccacc ttatgtggat aatgggcatc ataaaaataa
    24241 ccaaattcta caggaacgat gggctcgtta aaggtaatcc attgatccac taaatctcca
    24301 taagtctcaa aacaaaaacg agcatagtct tcataggctg agactgtcgc cttattttcc
    24361 caaccatcac catcctcttg aagggcaaaa ggtaaatcaa aatgatagag attgactaac
    24421 agacgaattc ctttagcctt aatagcctca aagaccttac gataaaaatc cacaccttga
    24481 gggttgactt tcccacagcc ttgtggaaaa atccgtgacc actgaataga agtccgaaag
    24541 actgtgtgac cagtctctaa caaaagctca atatcccgct cccaattttc ataaaaagtc
    24601 gatgtcttat ctgaaccaat cccattatag taacgatttg gctccacttg gaaccagtaa
    24661 tcccagagat tgtctccctt accgtcacca gctacacgtc cttctgtctg cggtccagaa
    24721 gtagaggatc cccagacaaa atcctttgga aatcttagca taacatttac ctctttatct
    24781 actcatttct cccattatac agaaaaaaca aggtaaaaac tagttacatt ttttccttgt
    24841 ttttcttctg attatagttt ttatttcttg cttaggattt caagcgtttc aagcacgtta
    24901 tctgcatgaa cctcaatggt gtcaccagtt gccttgatct taacttctac aatgccatcg
    24961 gccgcttttt taccaacagt gatacggatt ggaagaccaa tcaagtcact atcgctaaat
    25021 ttaacaccga cacgttcgtt acggtcatct gtcaagactt cataaccagc tcccatcaag
    25081 cttgcttcaa gtttttctgt caaggcttgc gcttcttcat ccttgacatt aacagtaatc
    25141 aaatgcacat caaatggtgc caattcttta gggaaattga ttccccaagc gtaacggtat
    25201 tcaccttttg gcgttttgtt aacaaagagg cgagcgtgtt gctccatcac tgctgaaaga
    25261 agacggctga caccgatacc gtaacatccc atgatgattg gcacagcacg accattttca
    25321 tccaagacat ctgctcccat gcttgctgaa tagcgagttc cgagtttgaa aatatgaccg
    25381 atctcaatac cacgcgcaaa gttaaggaca ccttgtccat ctggggaaat ttcaccctca
    25441 cgaacttcac ggatatccac atattctgca gtaaaatcac ggcctgggtt cacaccagtc
    25501 aagtggtagc catcttcgtt agcaccgaca actgcattgc gaacatcttg caccttacga
    25561 tctgcaataa ttttaatatt ctctggcaaa ccaactggtc caagtgaacc aaatcctgct
    25621 tgaacaacat tcgccacttc ttcttcgcta gcaacgtcaa agaaatctgc tcccaagtga
    25681 tttttcaact tgacttcgtt gagttggtca tttccaacta gaagggctgc aacaagctca
    25741 ccatctgcaa tgtagaagag ggttttaatc gtttgttctt ctggaacatt gaggaaagct
    25801 gcaacttcat caattgattt aacatctggc gttgcaacac gagtaacttc ttcttcagcg
    25861 acaacacggt tgcttggttt gtactcgttt gttgccattt ctaagttagc tgcatagcta
    25921 gactcacttg agtaagcaat ggtatcttca ccagagacta tccatttgag caattctgcc
    25981 ttgatttctt cttgcacttc tgcaggaatt tcgtcaaatg aggcaactga cttgtccaag
    26041 acaacccagc ggtcaaggtc tgtacgagca gatgtaatgg ccataaattc ttggctatcc
    26101 ttaccaccca tggctccacc gtcaccaata atagccttga agtctaaacc actacgagtg
    26161 aaaatacgct cataagctgc tttgtactca tcataaacac tatccaaact atcatagtta
    26221 gcgtggaaac tataagcatc cttcatgata aactcacgtg tacgaagaag tccattacgc
    26281 gggcgttttt catcacgata cttgggctga atttgataaa ggttgagtgg caattgcttg
    26341 taagatttaa cagaatcacg gacaatagct gtaaaggttt cttcgtgagt tggacctaag
    26401 ataaagtctg atttttcacg gttttttagt ttgtaaaggt cttcaccata ggtttcgtaa
    26461 cgacctgatt cacgccacaa ttctgcacta agaagggctg gagccaacat ctcaacagca
    26521 ccaatctttt cgaattcttg gcgcatgatg tttttagctt tttcaatcac acggttggca
    26581 agtggtagat aagaataaac acctgctgaa acttggcgaa cataaccagc acgcaacata
    26641 agagcatggc tgataacttg agcatcgctt ggcatttcgc gaagcgttgg gataggcatt
    26701 ttactttgtt tcataatatt cctcgattat ctaaaaaaga gtcgcataat gtcattccaa
    26761 gtcacagcaa tcatcaagac aaccatgatg accactccgg ccaaggtgac ataggtttca
    26821 atttcttgtt tcaatggttt gcggcggatg gcttctagga tattgagcac aatcttacca
    26881 ccatccaagg ctggaatcgg aataagatta aaaatcccaa tattgatgga aatcattgcc
    26941 aagaagtaca agatattttc aattccattt ttagcagcat cactacttgc cttaaagata
    27001 gcaacaggtc cacccaactt gttcaaatct ggttggaaaa tcagattttt cagagctgag
    27061 agaattcgga gagctgagtc agcagcagtt gtaaaaccac ctacaaacat ggatagaaaa
    27121 tctgacttaa cccccggttg aacacctaga aggtaacgac cttgactatc tttgggtgta
    27181 acagtgactt gtttgtcact ccccttttca gaaatagtca catccaaagt cggtgccgtc
    27241 ttatctttgg tttctgtttc cacagcttgg atcaagcttt cccagttgct aacctcatgt
    27301 gagccaatct tggtaatttg tgccgtttct ggtactccta ccttggccaa ggcaccttgg
    27361 ggcatgatat ggaactgatt ggtatcaaca tctctgacac caccctgcat aaagattaaa
    27421 acccaaaaaa caacgacacc taagataaaa ttgttcatag gacctgcaaa attggtaatc
    27481 agtttgcccc agatagtcgc attttgatat tgaacatcta aaggtgcaat ccgaacctca
    27541 gtaccatctg cttccacaac cgttgcatcg tgatccactg caaatgtttt ttcttcttcc
    27601 agaaccaatc ctttgataaa gagcttgtct tcaaaatcaa actgggtcac ctgcataggg
    27661 aggactgttt gatccaattt tttacctgag agattgatgc gtttaacctt accatcatca
    27721 gcaagtgtca aactaacagg cgttcctgtc ttgatttcag ttgtatcatc accccaaccg
    27781 gccatgcgga catagccacc cagaggcaag attcgaatgg tataggccgt tccatccttg
    27841 ccaatgtgag caaaaatttt aggtcccata ccgatggcaa attcacgtac taaaatccct
    27901 gatttcttgg caaagtagaa gtgcccgaac tcgtgcacca ctacaataat cccaaaaacc
    27961 agaataaagg ttaaaattcc aagcatagtg tttcctccgt cttttgatta aaagagtcca
    28021 aataagtgca tgattggaaa tacaagcaac atactatcga aacgatccaa aacaccacca
    28081 tgtccaggga taaatttccc agaatcctta acaccaaaat gacgtttgat cgaactttct
    28141 agtaaatcac caaattgtcc agcaatgcta aagaaaatag caaagactga catcttgtaa
    28201 attccatatg gaagagcaac tgtactgtca actatcataa agataatggt tactaaaatt
    28261 gctcctaaaa taccacccaa ggcaccctca agggttttat taggcgatac ccttggtgct
    28321 aactttcgtt tcccatagtt catcccaaca agataggcac cactgtctgt cgcccagacg
    28381 atacacaagg ctaagagagc cttgtccaaa cctgcaacac gagcatctag taaagcatta
    28441 aatccaaagc ccacgtagaa gctcatagca agagggaaaa ccgcatcctc aatcgtataa
    28501 gacttgctaa aaacggtcgt tcctaacatg attgaaatca aaacactata ggcaaccaca
    28561 ttcccatcaa ctggcaaaaa agtcaggtaa ttctccaagg gaatggtcaa tgcaaaggtt
    28621 gcaaagaggg tcaagaggcc ctccatcgtc atggtctcta gacctctcat cttcaaaagt
    28681 tcatgcatgg ctagcatggc tatgattccg attgctatct gaagcaagag gcccccaatc
    28741 attaaaattg gtaggaaaat agccagggca atccctgcaa acaaggttct tttctgtaaa
    28801 tcctgggtca tatttcctcc taaactcctc caaatcggcg atgacgacga ttataggcaa
    28861 gaatagcttc ctgcaaggcc gcttcgtcaa aatcaggcca taaggtgtcc gtaaaataaa
    28921 gctcactata ggctccctgc catggaagga aattgctcaa acgtaattct ccactagtac
    28981 ggataatcaa gtctgggtct cgtaagtcct taggcaaatg ctgagtaaag agatagttac
    29041 caatcaattc ctctgtgatg tcacctgggt tgattttggc atctaaaaca tcctgggaaa
    29101 tcaacttaag cgcctgtgta atctcagcac gtccaccata gttaagagca aaattaagaa
    29161 tcaatcctgt gttgttctta gtcaattcct cagccttggt taaagcttca aaggtttgct
    29221 taggcaggcg gtctgtctcc ccaatcattt gaatcttaac attattcgca tgtagttccg
    29281 ggacataatt atcataaaac tctactggca agttcatgat aaacttgact tcctgatctg
    29341 gacgggtcca gttttccgta gaaaaagcat agaccgtaat aaccttgacg cccagtttgt
    29401 tggctgcctt ggtcacggtt tgcaatgctt ccatgcccgc cttatgtcca aaaactcgcg
    29461 gttgcatacg ttttttagcc caacggccat tgccatccat gatgatgccg atatgagcag
    29521 gaacctgtgt cggaacctct acttccacag ccttatcttt cttaaaaaat ccaaacatga
    29581 tcttattcct attcaaaaat ctatcgtttc attataccat atttccccat tttcttctat
    29641 cactaagcta tttattctca ggcaccaagc ccatttttca aaaaaataag ccgcctgatt
    29701 gggcgacttt atttttatag ggagattatt atgaaaaagt tttaggagtt taagttaagg
    29761 tcttcttaac ttatgaactt agtgtacact ccctagctta aagtttcctt aagtattttt
    29821 aaaaatcaaa tttttccatt tctcctgcca atttttcttg gataaacgtg tttgatagag
    29881 ttccattcgg tcttcatttt ctaagaaatg aggagttgga cgaacttgaa aattcaaaat
    29941 atcctccaaa ccataaggta catagagttc aaaatctgat tcttcattca agcgcagtcc
    30001 aactgccgta caccgttctg gatacttact catagcatca cgagaactgg tataggaagc
    30061 agtgtgagga ctgtgctgat gcatatagac ctgatttttc aattcccact ggtactgagg
    30121 aaaatcctct ctcagctttt tctccagtaa taaggtttcc tcataagaaa aatctggatc
    30181 aaagaaaatc acatctatat ctgtttcatg atcaaaaggg gatttgtctg acaaaagatt
    30241 ccagatgaaa tttctgacag aacctgctgc caaccacgag tctttcaaac caaggtctcg
    30301 gatgatcgtc agaatggcca tcatatctgg actttctcta aaagcctcta agatttcttg
    30361 cttatttttc actgtattca taacctaagt gctcatatgc cttagcagtc gccacccgtc
    30421 cagaccgtgt ccgcatgata aaaccttttt gaatcaagta aggctcatac atatcttcaa
    30481 ctgtctcacg ctcttcggcg atattcacag aaagagttcc tagaccaaca ggtcctccac
    30541 tgtacatctc aatcatggta cgaaggattt tttgatccac atagtccaaa ccttcatggt
    30601 caacatccag catagtcaaa gccttatcgg taataatatc atcaattacc ccattcccca
    30661 ttatctgggc aaaatcgcgc acgcgcttga ggagacgatt ggcaatacga ggggtcccac
    30721 gactacgtag ggccaactca gatgctgcct catgagtgat ttccatctca aaaatatctg
    30781 ccgtccgctc gacaatttct gtcaagtcag catgggcata atactccata tggcctgtaa
    30841 tcccaaaacg tgcccgtagt ggatttgaga gcataccagc ccgagtcgtc gcaccaatca
    30901 aggtaaaagg tggtaactcc aaatgaacac tacgactacc ctcaccagcc ccaatcataa
    30961 tatctatgta gaagtcctcc atagcactat aaagcacctc ttccactgac attggcaaac
    31021 gatggatctc gtcaataaag aggacatctc caggctctaa ctcattcaaa atcgctacca
    31081 aatcacccgc tttttcgata acaggaccag acgtttgctt gagattgact cccagttcat
    31141 tggcaatgac aaaagccatg gttgttttcc caagccctgg agggccaaat aagagcacat
    31201 gatccagtgc ttcatcccgc attttagcgg cttcgataaa gatctgaagc tgatccttaa
    31261 ccttatcctg accaatatat tcacgtaaat actgaggacg gagcgtgcgt tctactaact
    31321 cctcatcacc catcatctca ttatctaaaa ttctactcat ggctctatta tatcaaaaaa
    31381 acaagccaca aacaaaaaag ccacctgatt gggtgactcc taagtttagc acttatgtgg
    31441 tataatatta tacgacactg ctacaccgcc tacgaaagga ggtgagatag cccatgatgg
    31501 aattagtact caaaactatc atcggaccaa ttgtggtcgg tgtcgttctt cgtatagtcg
    31561 ataaatggct aaacaaggac aaatagtgtc aaaaaagacc tcaagcttat ttggtcgtga
    31621 gcttggggtc ttttctagcc tatgatatag aactagtact caattccttt ttattatcac
    31681 atagttcacg aattttgtca aaggtttaca ttttcttcaa ccgctgtacg acaagacggt
    31741 taagattaag agaacgttag ggattctatc aatttcatag aaattttgat ttcgtaaacg
    31801 aagagacaat cttacatgtc acttctcatt taatacgcca ctactagaca agcaaaatca
    31861 ttattacagt agttccagtt cttcaattaa cagtcactta caatcaaatt gagtttgaac
    31921 tagctgaagc gaccacagac ctatttctta gtcatattcg ctaaaaaagt ccccgccaat
    31981 tccccgacca aaatccgaaa aataccgaaa aatatcgaaa aattattttt agaatagtcc
    32041 ccaaaagcct gaaatagagc taaaaaactc cacctgattg ggtggagtta agggagatta
    32101 ttatgaaaaa gaaaagttta ggattttatt aaataaagtt aggaggtctt tatttaataa
    32161 ctacatgata caagacgaaa cttaaaacta gcttaacttt tctaaa
//
LOCUS       DAVLUM010000023        30612 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLUM010000023 DAVLUM010000000
VERSION     DAVLUM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.023"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            229..882
                     /locus_tag="VYN42_000866"
     CDS             229..882
                     /locus_tag="VYN42_000866"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1461964.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            892..1356
                     /locus_tag="VYN42_000867"
     CDS             892..1356
                     /locus_tag="VYN42_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1461965.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1369..2637
                     /locus_tag="VYN42_000868"
     CDS             1369..2637
                     /locus_tag="VYN42_000868"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1461966.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2651..2911
                     /locus_tag="VYN42_000869"
     CDS             2651..2911
                     /locus_tag="VYN42_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461967.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2922..4283
                     /gene="pdrM"
                     /locus_tag="VYN42_000870"
     CDS             2922..4283
                     /gene="pdrM"
                     /locus_tag="VYN42_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1461968.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4437..5405
                     /locus_tag="VYN42_000871"
     CDS             4437..5405
                     /locus_tag="VYN42_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1461969.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5421..6413
                     /locus_tag="VYN42_000872"
     CDS             5421..6413
                     /locus_tag="VYN42_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1461970.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVVPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     AVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6631..7674
                     /locus_tag="VYN42_000873"
     CDS             6631..7674
                     /locus_tag="VYN42_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1461971.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFDPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7738..9423
                     /gene="lpdA"
                     /locus_tag="VYN42_000874"
     CDS             7738..9423
                     /gene="lpdA"
                     /locus_tag="VYN42_000874"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1461972.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9487..10476
                     /locus_tag="VYN42_000875"
     CDS             9487..10476
                     /locus_tag="VYN42_000875"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1461973.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANITESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10551..11621)
                     /gene="xerS"
                     /locus_tag="VYN42_000876"
     CDS             complement(10551..11621)
                     /gene="xerS"
                     /locus_tag="VYN42_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1461974.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(12205..13755)
                     /locus_tag="VYN42_000877"
     CDS             complement(12205..13755)
                     /locus_tag="VYN42_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1461975.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIIGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13771..14550)
                     /locus_tag="VYN42_000878"
     CDS             complement(13771..14550)
                     /locus_tag="VYN42_000878"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1461976.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKD
                     LNDSKKIPKKKHLEIFQAVQDQSLSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14537..15388)
                     /gene="ylqF"
                     /locus_tag="VYN42_000879"
     CDS             complement(14537..15388)
                     /gene="ylqF"
                     /locus_tag="VYN42_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1461977.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQVIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15607..15783)
                     /locus_tag="VYN42_000880"
     CDS             complement(15607..15783)
                     /locus_tag="VYN42_000880"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1461978.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(15835..21726)
                     /gene="iga"
                     /locus_tag="VYN42_000881"
     CDS             complement(15835..21726)
                     /gene="iga"
                     /locus_tag="VYN42_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HEV1461979.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGATDLFSTLEHYRKVFLPNTSNNDWFKSQTKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGSRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(21935..23113)
                     /locus_tag="VYN42_000882"
     CDS             complement(21935..23113)
                     /locus_tag="VYN42_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461980.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSFIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(23283..26933)
                     /gene="addA"
                     /locus_tag="VYN42_000883"
     CDS             complement(23283..26933)
                     /gene="addA"
                     /locus_tag="VYN42_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1461981.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQKGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVKLMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(26930..30205)
                     /gene="rexB"
                     /locus_tag="VYN42_000884"
     CDS             complement(26930..30205)
                     /gene="rexB"
                     /locus_tag="VYN42_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1461982.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
BASE COUNT         8594 a         6118 c         6343 g         9557 t
ORIGIN      
        1 ttttaatatg tttaaaaata tttcagaaaa gataatcttc gaaagaggta gtaaaatgct
       61 taatgattta aaaagtaatt ataaaaaata gccagtcttt ataaactgta ttcacgtatt
      121 caaatcgtat atatagtcga tttattaaat ctttagataa actgtaaaaa gtggtttcca
      181 tagccacttt ttgctataat agaggcagta aaaatgaagg agttggctat ggaacactcg
      241 tcttggcacg ctttgattaa ggcgcaatta cctgagggtt atttcgggaa aatcaatcag
      301 tttatggagc aggtctattc tcaggggact atttatccac ccaaggaaaa ggtttttcag
      361 gctctcttga caacactgct tgaagaagtt aaggtggtaa ttctagggca agacccctac
      421 cacggaccag gtcaagcgca gggcttgagt ttttctgtac ctgactctat cccagctcca
      481 ccatccttgc aaaatatctt gaaagaattg tcagatgata tcggagttaa gaaatctcat
      541 gatttgacag cttgggctga gcaaggagtc ttgcttctta atgcttgttt gactgttcct
      601 gctggacagg ccaatggtca tgctggtcaa atctgggagc cttttactga tgctgtgatt
      661 caggtggtca atcatctaga tagaccagtc gtttttgtac tctggggagc ttatgcacgt
      721 aagaagaagg cattagttac caatcctcat cacttgatta tcgaatcagc ccatccaagt
      781 cctttgtcgg tttatagagg attttggggt tccaagccct tttccaaggc caatgcattc
      841 ttaaaagaga caggacaaga gccaatcgat tggcttagat aaggagaaaa tatgcctcag
      901 ttagcgacga tttgctacat tgataatggg aaagaactgc tcatgctcca tcgtaataag
      961 aaacccaatg atgtccatga agggaaatgg attggtgtgg gtggtaagct agagagagga
     1021 gagacgcccc aggaatgcgc ggcgcgtgaa atccttgaag aaacagggct caaagccaag
     1081 ccagttctaa aaggtgtcat cacttttcct gaatttacac cagatttaga ctggtacacc
     1141 tatgttttta aggtgacgga gtttgagggc gacttgattg actgcaatga ggggacgcta
     1201 gaatgggttc cctatgatga ggttttgagc aagccgactt gggaaggtga ccacaccttt
     1261 gttgagtggc ttttagagga taaacccttc ttttcagcca agtttgttta tgatggggat
     1321 aaattgttgg atacccaagt tgatttctat gaataaagga gaaagcagat gctactaatc
     1381 aaaaatggtc gtgtaatgga tcctaagtct ggtttggatc aagtttgtga tgtcttagtt
     1441 caagatggga aaattatcaa aattgcgcct gagatcacgg aagaaggagc agaaacgatt
     1501 gatgctactg gtcttgtggt tgctcctggt ttggtcgata ttcatgtgca tttccgtgaa
     1561 cctggtcaaa cacataaaga agacattcat actggtgccc tggcagccgc tgcaggtggt
     1621 tttactactg tcgtcatgat ggctaatacc agtccaacca tttcagacgt ggagactttg
     1681 caagcagttc tccagtcagc tgccaaagag aagattaatg tcaagacagt tgcgaccatt
     1741 actaaaaact ttaatggtaa aaacttgact gactttaagg cgctcttaga agctggtgcg
     1801 gttggtttct ctgatgacgg tattccgctt gagagcagta agattgtcaa ggaagccatg
     1861 gaggaagcca aaaaactcaa tacctttatc agccttcatg aggaagatcc aggtttgaac
     1921 ggtgttcttg gctttaatga aaatattgct agagaacatt tccatatctg cggtgctact
     1981 ggggtggctg agtacgctat gatggcgcgt gatgtcatga ttgcctatgc aactaaagcc
     2041 catgttcaca tccagcattt gtctaaggaa gaaagtgtta aagtagtgga gtttgctcag
     2101 gggttaggtg cagaagtcac agcagaagta gcaccacagc atttctctaa gacagaagca
     2161 cttcttttaa cacaaggtag caatgctaag atgaatccac cgcttcgttt ggaatcagac
     2221 cgtcgtgccg ttatcgaagg tctcaaatca ggtgtcatca cagttattgc gactgaccac
     2281 gcgcctcatc atgtagatga aaaaaatgtt gaagatatta ccaaagcgcc atctggtatg
     2341 actggcttag aaacatccct gtctctcggc ttgacctatt tagtagaagc tggtgagttg
     2401 agcttgatgg aattacttga aaaaatgaca tacaacccag ccaagcttta caactttgaa
     2461 gcaggttact tggctgagaa tggtccagca gatatcacta tttttgatgc caaggctgac
     2521 cgccttgtgg actcccattt tgcttccaaa gcagctaatt caccattcat cggtgaaacc
     2581 ttaaaagggc aggttaaata taccatctgt aagggacaaa tcgtctatca agcttgatag
     2641 gagttagaat atgaattatt ttcgaaaacg tagggagaga caagcgaaat ctaatagtgg
     2701 aatttactgt cccgcagcta atcgttccaa aattcaatat gaaactaaag aaaaagctga
     2761 ccatgcggtt caatatgata acggaggttt agttagaagc tattattgtc gtacatgtgc
     2821 gtgttggcat actacttcaa aatctaataa acctccgcta agtttgaaaa actatggtct
     2881 gaaactcttt ggtttagata aatcagaata gaaagagaag tatgtataag acaaagtgtt
     2941 tacgagagaa gttagtatta tttttaaaaa ttttcttccc aatcctgatc taccaatttg
     3001 ccaattattc tgcctctttt gttgatactg caatgacagg tcaatacaac actatggact
     3061 tggctggtgt atctatggca accagtatct ggaatccttt ctttacattt ctaacaggga
     3121 ttgtgtcagc cttggtgcct atcattggtc accatcttgg tcgaggcaaa aaggaagaag
     3181 ttgcgtctga tttttaccaa tttatttatt tggccttggg cctatctgtg gtcttgctgg
     3241 ggatggtact tttcttggca ccaacaatct tgaatcatat tgggttagaa gcagcagtag
     3301 cggcagtagc ggttcgctat ctttggtttt tatctatcgg gattatcccc ttgttgctct
     3361 ttagcgtcat tcgttccttg ctggattcgc tgggcttgac caaactgtcc atgtacctca
     3421 tgcttttgtt actccctctc aatagcggat ttaactatct cttgatttac ggtgcctttg
     3481 gtgttccaga actgggaggg gctggtgctg gtttaggaac atccttggcc tactgggtct
     3541 tgcttgggat ttctgttctg gttttattta aacaggagaa gctcaaagcc ttacaccttg
     3601 agaaacgaat tccacttaat atggataaaa ttaaggaagg agttcgttta ggtctgccta
     3661 ttgggggaac tgtcttcgcg gaagtggctg tcttttcagt ggttggcttg attatggcta
     3721 agttttcgtc cttgattata gctagtcacc agtcagctat gaacttttca agtcttatgt
     3781 acgcctttcc tatgagtatc tcatcggcta tggctattgt cgtttcctat gaagtgggag
     3841 ccaagcgatt tgatgatgcg aaaacctata ttggtctagg aagatggact gccctcattt
     3901 ttgcggcctt caccttaacc ttcctttaca tttttagggg aaatgtggcc agtctttatg
     3961 gtaacgaccc aaaatttatc gatttgacag cgcgtttttt aacttatagt cttttcttcc
     4021 agttagcaga tacctttgcg gcgccgcttc agggaatttt gcgggggtat aaggatacag
     4081 ttattccttt ttaccttggt ttgcttggtt attggggcgt agcaatccct gtggctacgc
     4141 tatttgattc cctaacagat tttggagctt attcttactg gatcggcttg attattagtt
     4201 tgattgtgag tggggcgctc taccgttggc gtttaactgt gattatgaag agatttgaat
     4261 ctttagcaaa atccaaacgc taaaaagttt gtgaaaaaat atccttgaca agaaaatccc
     4321 ttgttttcac ggggttttct tttttatttt gtgaaatttc ttttagaaaa actttgacag
     4381 tatttgccaa aagcggtaaa atagtaaggt aagaagaaag ttagaaaggc aagaagatgt
     4441 caactttaga taaaaatctt ttgctagaaa tgttccgtaa gatggaagaa atccgtcgca
     4501 tggacttaaa aattgcacaa ttagtaaaga aagggaaagt gccaggaatg acgcactttt
     4561 ctgttggtga agaggcagct aacgtggggg ctatgttagc tctcaatcca gatgatctga
     4621 ttacctcaaa ccaccgtgga cacgggcaag ctattgctaa agggattgac ctcaacggaa
     4681 tgatggctga aatccttggt aaatacactg gaacctgtaa agggaaaggt ggatctatgc
     4741 atatcgctga ccttgatgct gggaaccttg gtgccaatgg tatcgtaggt ggtggtatgg
     4801 ggatcgctgt cggtgcagcc ctcagtcagc aaatgcaaaa taccggtaaa atcgttgtct
     4861 gcttctttgg agatggtgcg accaatgaag gtgttttcca cgaagcagtg aacatggctt
     4921 ctatctggaa cctgccagtc attttctatt gcattaacaa cggttacggt atctctgcgg
     4981 atatcaagaa aatgaccaat atagaacata tccatcaacg tagcgccgct tatggaattc
     5041 ctggaatgtt catcgaagac ggtaacaatg tcatcgatgt ctatgaagga tttcagaaag
     5101 ctgtagacca tgttcgcagt ggcaatggtc cagtcttgat tgaaagtgta acttatcgct
     5161 ggctcggtca ctcatcatct gaccctggta aatatcgtac gcgtgaagaa gtggaattgt
     5221 ggaaacaaaa agatccaatc gaaaacctcc gcaattacct tattgaaaat aacattgcaa
     5281 gtgccgaaga attggaagaa atccaagcgc aagtaaagga agcagtagaa gcttctgtta
     5341 aatttgcaga ggaaagccca ttcccaccgc ttgaatcagc ctttgaagat atttacgcag
     5401 actaaggaga aagagataaa atggaaacaa aaacaatgtc cttccgtgac accattatcc
     5461 ttgctatgtc tgaggaaatg cgtcgcgatg aaaatgtgtt cttgatggga gaagacgtcg
     5521 gtgtcttcgg aggagacttc ggtacttctg ttggaatgct tgaagaattt ggtccagaac
     5581 gtgtccgtga ctgtccgatt tctgaagctg ccatctctgg agctgcagca ggagcagcca
     5641 tgacaggact tcgtccaatc gtcgatatga ccttcatgga cttctctgtt attgccatgg
     5701 acaatatcgt caaccaagct gctaaaacac gttacatgtt tggtggtaaa ggtcaggttc
     5761 caatgactgt tcgttgtgca gctggtaacg gagttggctc tgccgcccag cactcacaat
     5821 ctctagagtc ttggtttact cacattccag gacttaaggt tgtggtacct ggaacacctg
     5881 cggacatgaa aggcctgctt aagtcttcta tccgtgataa caacccagtt attatacttg
     5941 agtacaagtc agaatttaac caaaaagggg aagtgccagt tgatccagac tacacaattc
     6001 cacttggggt tggtgaaatc aaacgccaag gaacggatgt aacagttgtt acttatggaa
     6061 aaatgcttcg ccgtgcggtt caagctgctg aagaattagc agaagaagga atttcagttg
     6121 aaattgttga cccacgtacc cttgttccgc ttgataagga tatcatcata aactcagtga
     6181 agaagactgg taaggttatt ctggtcaacg atgcccacaa aacaagtggc tatatcggtg
     6241 aaatttcagc tattatttca gaatcagaag catttgacta tctagatgca ccaatacgcc
     6301 gttgtgcagg agaagatgtg ccgatgcctt atgcacaaaa cctagaaaat gcaatgattc
     6361 caacagttga aagtatcaaa gatgcaatcc gaaaaactta taacaaagac tagggttaca
     6421 taatataagt tatgtaaata aaataaagct gacgagaaac tttgtatctt ttaggtgcag
     6481 agctcttcgt cattaatatc ttagattaga gcacgggcta aaagatcgga aaaaagataa
     6541 atctccttgg cttcatcgaa gccatcgtcg atttcctatt tttcagtcgc ttttgacgcc
     6601 ctttgtatca taaatagaat tggagaggtc atggctgatg acaagctaag agcgactcct
     6661 gcagctagaa agttagcgga tgatttaggg ataaacctct acgacgtttc tggctcaggt
     6721 gcaaacggtc gtgtccacaa agaagacgtg gaaacttata aagacacaaa cgtggttcgc
     6781 atttcgccac ttgcaaaacg aattgccctc gaacataaca ttgcttggca ggaaatccaa
     6841 ggaaccggtc atcgtggtaa aatcatgaag aaggatgttt tggccctgct tcctgaaaat
     6901 atcgaaaacg atagcatcaa atctcctgct cagattgaaa aagtggaaga agtccctgat
     6961 aacgtaacac catatggtaa aatcgagcgt attccaatga caccaatgcg taaggttatt
     7021 gcccaacgca tggttgaatc ttacttgact gcgccaacct tcaccctcaa ctatgaagtt
     7081 gatatgactg aaatgttggc tcttcgtaag aaggttcttg agccaatcat ggaagcaact
     7141 gggaagaaga ctactgtaac agaccttctt tcgcttgcag ttgttaagac tcttatgaaa
     7201 cacccataca tcaatgcttc attgacagaa gatggcaaga ctattatcac tcacaactat
     7261 gtcaatcttg ccatggcagt tgggatggat aatggattga tgacacctgt tgtttacaat
     7321 gctgagaaga tgagtctttc agaactggtt gtagccttta aggatgttat tggccgtacc
     7381 ttggatggta aattggctcc aagtgagtta caaaattcaa cattcacaat cagtaatttg
     7441 ggaatgtttg gtgttcagtc ctttgacccg attattaacc aacccaactc agctatcctt
     7501 ggtgtcagtt cgacaatcga gaagccagtt gtcgtcaatg gtgaaattgt gattcgccca
     7561 atcatgagtt taggattaac cattgaccac cgtgtcgtag atggtatggc tggtgctaag
     7621 tttatgaagg acttgaaaga gttgattgaa accccaatct caatgttgat ttaagagcaa
     7681 gagtattcat ttttaagata tagataaagg aaggaagaca tggccttaga agtaattatg
     7741 ccaaaagccg gcgtggatat gacagaagga caaatcgtcc aatggaataa aaaagtcgga
     7801 gaatttgtaa aagaaggaga aatccttttg gaaatcatga ctgataaagt cagcatggaa
     7861 ttggaagccg aagaagatgg gtacttgatt gccattctca aaggagatgg tgaaactgtc
     7921 cctgtaacgg aagttatcgg ttaccttggt gaagaaaggg aaaacatccc aacagctgga
     7981 gcagcatcgc cagaagctag ccctgtacct gtagcaagta cctcaaacga tgatggtaag
     8041 agcgatgatg cttttgatat cgttgtgatt ggtggaggtc ctgctggtta tgttgcagcc
     8101 attaaagctg cccaactcgg cggtaaggtt gcccttgttg agaaatctga acttggtgga
     8161 acctgcttaa accgtggatg tattccaacc aagacctacc ttcataacgc tgaaattatt
     8221 gaaaatatcg gtcatgctgc aaatcgtggt atcgtgattg aaaatcctaa cttcactgtt
     8281 gatatggaaa aacttttaga aactaaatct aaagttgtta atactcttgt tggtggtgtt
     8341 gcaggacttc ttcgtagcta cggagttact gttcataaag gaattggtac aatcactaaa
     8401 gacaagaacg tcttggtaaa tggttctgaa ttgcttgaaa ccaagaaaat cattcttgct
     8461 ggtggttcaa aagtcagcaa gatcaacgtc cctggtatgg aatctccact tgtcatgact
     8521 agtgatgaca ttcttgaaat gaacgaagtg ccagaaagcc ttgttatcat cggtggtgga
     8581 gttgtcggta tcgaactcgg tcaggccttc atgacatttg gttcaaaagt gactgttatc
     8641 gaaatgatgg accgtatagt tccagctatg gatgcggaag tttctaagaa ccttcgcttg
     8701 atccttgagc gtaaaggaat gaccatcttg actggtacta aactgcaaga aatcattgag
     8761 gaaaatggtc aacttcgtat caaggttgaa ggaaaagacg atatcatcgc aagcaaagct
     8821 cttctttcaa ttggtcgtat gccagacctt gaaggtattg gagaggttga gtttgaattg
     8881 gatcgtggtt gtatcaaggt caacgaatac atggaaactt cagttccagg catttatgca
     8941 ccaggtgaca tcaacggtac taagatgttg gctcacgcag ctttccgcat gggtgaagtt
     9001 tccgctgaaa atgcccttaa aggaaatcat gcagttgcca aattgaattt gactcctgca
     9061 gccatctaca ctctccctga agtagcagca gtaggtttga cagaagaaca agcccgtgag
     9121 aaatacgatg ttgccatcgg taagtttaac tttgctgcta acggtcgtgc tattgcatct
     9181 gacgcagctc aaggtttcgt aaaagttatc gctgataaga aatacggaga aatccttggt
     9241 gtacacatta ttggtcctgc agccgcagaa ttaataaacg aagcatcaag catcatcgaa
     9301 atggaaatca ctgttgagga aatgctgaag accatccacg ggcacccaac ttactctgaa
     9361 gtgatgtacg aagcgtttgc agatgttcta ggaatggcca tccattcacc taagaaaaaa
     9421 taaaacgaag atagattaga ctggaaggtt atttccagtt tctatcatat aaagtaaagg
     9481 gatatcatga aatacattat caatcattca aatgacactg cttttaatat tgccttggaa
     9541 gaatacgcct ttaaacacct tttggatgag gatcaaatct tcctactttg gattaacaag
     9601 ccatctatca ttgttggtcg tcaccagaac actatcgaag aaatcaaccg tgattatgtt
     9661 cgcgaaaatg gtattgaggt agttcgccgt attagtggtg gtggagctgt ttaccacgat
     9721 ttaaataacc tcaattacac gattatctcc aaagaagatg aaaataaggc atttgacttc
     9781 aagagcttct caactccggt tatcaatacc ctggctcaac ttggggttaa agctgagttc
     9841 acaggtcgta atgaccttga gattgatggt aagaagttct gtggcaatgc ccaagcctat
     9901 atcaacggcc gtatcatgca ccacggttgc ttgctctttg acgttgattt gtcagtcctc
     9961 gcaaatgccc ttaaggtttc aaaagataaa tttgaatcaa aaggtgtgaa atccgtccgt
    10021 gcccgtgtaa ccaatattat caatgaatta ccaaaaaaaa tcacagtcga aaaattccgt
    10081 gatttactct tggaatacat gaaaaaagag tacccagaga tgactgaata cgtcttttca
    10141 gaagaagaat tggccgaaat caatcacatc aaggatacta agtttggaac ttgggactgg
    10201 aactatggta aatcacctga atttaacgtc cgtcgtggaa ccaaattcac tagtggtaag
    10261 gttgaagtct ttgctaacat tactgaatca aaaatccaag acatcaagat ttatggtgac
    10321 ttctttggta ttgaagacgt tgctgcagta gaagatgtcc ttcgtggggt gaaatacgaa
    10381 cgcgaagatg ttcttaaggc gctaaaaacc attgatatca cacgctactt cgctggtatt
    10441 agccgtgaag aaatcgctga agcggtagtt ggataaatca aaaaaagaag ttggccaact
    10501 aaccaacttc tttttttgat atttatttac ataatttaaa atacgtaaaa tcataaacta
    10561 tccagagcat tcttttgttc atcattaaca atatgggtat agaggtcagt gacttgtgtg
    10621 ctggcatgtc ctagttggtg actgactaaa acttgtgatt tagtcgcatc atagagccta
    10681 gttgctagtg tatggcgcag tttatggggt gttacacgta ctttaaaatc ctctgagtat
    10741 ttagcaacca ttttctcaac gctagaagca tcgatacgat taggaacacc tctgtagaga
    10801 gttaaaaaaa gggctgtatc tgttttttcc gttttatagc gttgattccg aatggccaga
    10861 taattctcta aataaggttt agcaaaagca gcgacattga ctgagtcacg tttgccacct
    10921 tttcgagtaa catcaataac catcattttt agattgagat ctcttagatc tagattaaca
    10981 gcttcagata agcgaacacc agatgccaag agaagggcaa taatggctaa atctcgttct
    11041 ttatttttgt tgaatgatga gagagctcga tttgaaagct gttgtgggtg ctcttgatcg
    11101 atataagtta gaaaaccttc tgtttcatca cctagaaaga gtttttgctt gatattttca
    11161 gctctggcag caagggtttc tttctttttc ttggttgaaa cttttttcat tacattacga
    11221 tagaaataag gttccccctg atcgttttca acctcctcgg ttagatactt gtaaagacta
    11281 gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa caccttgttt tgttgtatta
    11341 gcattcagca agggacgttc acgtagataa aggataaagg attccatgtc tttcttagac
    11401 atattttcca aaactgataa aggaatatcg gatattttat cagcgtttga aataccagac
    11461 tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt attcgtacag ggttgtaaaa
    11521 ctgtagggca cagccagctt agattggtag tattccagaa cataccaggg catgagttgt
    11581 tttagtttgt cgattcgttc cagtaaaatc tcacgtttca tgtattttct ccataagtaa
    11641 gtatactagt agtatagcat agacttgtat atttttcaag aaaattatag tttttcggaa
    11701 agatgttata ggagtttttc aaagtgataa aaagacttag acctacaaac aaaacagaat
    11761 aaggaaaata ataaaaatct cacccactaa acttctgtta atactacata actgaagagc
    11821 tatataagaa gctatgagat acaaaacaca ttgtataata gattgaaact agaatagtac
    11881 atctggactt ctaaaacatt gctagaaatt gatttgattg tcctgattgt tttatcctat
    11941 ttctatttca tttctctata taattgctat tgttttcttt ttcatgattt taatcttact
    12001 gtacagattt gatacagtaa actcctttct agctttatac tttatcattt ctaacttaat
    12061 tatagtctta tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa
    12121 ataaccgatc tcatttctga gaatcggttt tctaaataaa tcaaactgat catttacata
    12181 acataaatta tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact
    12241 ttttggaata accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt
    12301 ttggctcttg ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc
    12361 atgaacttgt ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc
    12421 ttcgctagat acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc
    12481 tttgagcaaa tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt
    12541 gcgaatatct cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat
    12601 ggctccaaaa tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac
    12661 aagtccaaga ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa
    12721 aatggggagg aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa
    12781 gcggattaaa aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag
    12841 gacaagctga tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag
    12901 gataaaagcc aagatgggat aataagccct atccaaatgg attttttgac caatcaagtc
    12961 ataaactctt ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa
    13021 aattcccatg acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg
    13081 catatccaat actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct
    13141 ggctgctaga gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac
    13201 aaagagaagt gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact
    13261 ggcaatcaag gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc
    13321 accaactgct ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat
    13381 agcaagaata cctagcacat attttttcca aagaatgccc caccagttga gggacatgag
    13441 gcctttcagt tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg
    13501 tgttagtttg gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt
    13561 gcgcactaag tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat
    13621 taagaaacga aaggatccga cgataattcc aacgatgagg ccgataatga ttcctcgacc
    13681 aacttgggat agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc
    13741 cgactgttcc tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga
    13801 tttaacgggt tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc
    13861 cagatgttta gctgtgccat atcctgcatt agtagcgaaa tcatagccag ggaactgctg
    13921 atcgtattcc ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat
    13981 agagagggag ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt
    14041 catggcatca atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat
    14101 ggctagtttg gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc
    14161 aattccaatc gacaaggatt ggtcttgaac ggcttggaaa atctccagat gtttcttttt
    14221 aggaattttc ttgctgtcgt tgagatcttt aatcttacaa tttttaggta aaatgacggc
    14281 cgcagcgact acaggaccag caagaggacc acgaccaacc tcatcaatac ctacaattaa
    14341 ggtcaatcct tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt
    14401 ttcatctaat tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga
    14461 gcgattatcc ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag
    14521 gagttctttg atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt
    14581 taccgagttt gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat
    14641 cacggaaacc gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt
    14701 tcatttgttt gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac
    14761 caaaaatggt aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca
    14821 acttaagtgc aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga
    14881 tttccagatc tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc
    14941 caacaacagc aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg
    15001 gaatcccgat aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag
    15061 caatcttatc agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct
    15121 ctttggagtt gatagctagc gtctggatta cttgtgattc aaaatactga cgccattcct
    15181 tggtcattgc tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac
    15241 caacaatctt ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa
    15301 tcgtcacaaa atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt
    15361 gaccaggaaa ccattgaata gtagccattg agttttttcc tttcgtagca aggatttaga
    15421 tcccctattt tattttacta tagtttgaac atagagagtc ttcaaatgga tgatgtccaa
    15481 acagttcttg ttttatgaca tagaaatcta ctttatatta tatcatgcct tctttatttt
    15541 gtccgatgat agccttttac cctatctttt accctatata gaaaaaagcc atcaaatgat
    15601 gacttttcag agggagcaaa aaactgttcc cgtcatattg tgaaccaaaa gaactaaact
    15661 accaacagct aataggccta aagctgtaag tgcagaagtt gatgaacctg ttgcaggaag
    15721 agtttcctgc tgataaataa gagcataact tacttcatta tcagtaggaa ttcctgcttg
    15781 aatcttggtt tgttcttcat caccttttta aactttattt cctaatagta aacactattt
    15841 tttattctca aaaattgaac ttctaaaatc atttgtttgg tcaagatagg ctttaaagat
    15901 tgctctcttc aacttatgaa cggcactgtc gatttctgga tcataattac tccaacgtga
    15961 accttcagca tccttgagaa cagcttggtc catgagggct tgcaattcat ccacattatt
    16021 gatagtcttt gtgccatagc ttggccatgg ttttgtcgga tctttaaagg tcacctgctt
    16081 caagtttcca aactgatcca cccgttcttg gtacatagct gtcttaaatt ctgcccaagt
    16141 tttatactta ccgtcaaata cctttttcaa aacaagctca tcggtcacca agccccgttc
    16201 tttaccataa agattgatag tttgcccttg ttgtttagca tcttcttcgt attggtttga
    16261 gatataaggt accattccat ccttaaagcc tttggcagcc aaaagttcgt acgcaatcct
    16321 acgtcccata aggtcccctg gtgtgccttt ctcactgctg agagctgaat agattggggc
    16381 aaagagtttg atggtatagt agccatttcg ttcatagtcg ccagactggt actcacgagc
    16441 tgataagatg ttgtggtcaa tcaaactttc aaaactattc aggtttcggg cctctgcttc
    16501 tgtcaattct ttgactacgt tagtggcata aacctcattt ccatctgctg gatctttcac
    16561 atacttgttc tcaatttttc tgagagccgc cattttctgg taaacactta gtttattaac
    16621 gattgactgc ccttcgagat attccatcat gtagataagg tcaaacatgt tatggacata
    16681 gttctgaaga tctgctgcgt tttggaatct ctctgtcgga tccaagactt gaagacggga
    16741 tccctctgta ctatctgatt ttgagtgttt caagatagaa ttaatggtaa tggttgcgtc
    16801 acttggttgg tcaggggctt gcaataagcc ttttgcgaag aactctggtc ccaagccatt
    16861 tcttcgacca tagccaccaa ggtaaatatc ctgatccgaa tcatgggtca tttcatgggt
    16921 ataagtaatg gctccatcct tgtccagcat gcggtaagac atatagtaga cgccgtcccc
    16981 tgtagcgtag gctccatgct ggttgtgtac taccttattg ccaactggtc caaagaagtt
    17041 cttcatagct ggattggagc tatcaaactt agcctccgct gtagcttttc ctgatgttgt
    17101 gtcatcccca aacttatagg catcataaag gagaatcgta cgatagagtt tttcgcgtga
    17161 ctgttcatct aaaatacgat accaataatc gtagtgatct cgctgacgtt tggctgtttc
    17221 acgcgcattt tcttcaacaa aatcattgag agccttgccc gctttatggt cactactgcg
    17281 gtagcgatca taagctccaa atcctagact agacatggtc gagatgacaa atacggatct
    17341 ctctggcaag gtcaggagag gcaagaccat attgcggtat ttccatgtgg cactcgtgat
    17401 acgatcataa acaccgatag aatacttggt gccagctaac ccttgcttcg ttttcacctc
    17461 ttcgatagtg gatttttctt cgacaatgta agccttagtc tgtgatttaa accagtcatt
    17521 attgcttgta tttggtaaaa agacttttcg gtaatgttcc agcgtgctaa acaaatctgt
    17581 cgctccatgt tgactggcaa gactgatacc ataagtatcg acattattct tagctagaag
    17641 attgttaaag ccagatttac ctaactcaat cagagtatct agtggggaag tatttccttt
    17701 accaaagaag tctggatgat acataactag gtctttgaca ttcacttgac catagttaaa
    17761 gttataccaa cgttctaaat aagttaaacc gagtagcaag gcttccttat tattcttgat
    17821 tttatctaca agatagcctc tggtgactga gttatcgcta gctagaccgg catctgctga
    17881 caaaagtttt ttcaagctgt ctcccagatt ttgttttgtt ttggagaact ggtcttctaa
    17941 atagagctcg gttaacttaa cttctggaga aataccaagt gtctttctga tagcatctga
    18001 ctggtaatca agcttctgca actcaggcaa gacttcctta acaatagagt ctcgatcata
    18061 taagaattgg ttaggagtgt agagaagtcc cgtattacct agattatatt ctgctagatt
    18121 ggcaaaatca gtctggtact tgagatcaaa tttctcagat gaatggtcat tatagtgaag
    18181 taagagtttg tttgcagtct gtttgttgga aacaatatct gtgattactt ggtcatcctt
    18241 catcataact gcagataaga gttctttttg gtataagaga ctgttctcct taaccaggtt
    18301 tccgtatttg acgatggttg acttattata aaaaggtaac aatttttcaa tgttcttata
    18361 aaccaaagca cggttagctt gataatgggc tatcttagaa aaatcactgt ctttcttgcc
    18421 acttgttgag aggggttcca ccgttggtag agtgagagga tttatttctg cttttttgct
    18481 tacaatttga gaagcatcta gcattgttcc tctttcttca aaggattcct tgctgacgac
    18541 ctcatccttc tctaaagtga cattgaaaac tctattagcc ttactactaa atgtattagc
    18601 taccttcatt cctgtatagt ggtatccagt gatggcattt ccgtttgtta cattgacatc
    18661 gctaagaaca ttggtcaatt caccagcgtg tttttcctca ccagaagttc gatcccacaa
    18721 atatcctgcc acaccagcga ctttaccaaa gtgcttgaca ttattaatat caccttccgc
    18781 ataactgttc tgtatatgcg catcttggtc tactagacct gcaagaccac cgacagtctg
    18841 atctgaccta ttggtgtttg acgaaatggt tactgtcgct ttggatttag caatagacgc
    18901 attttttcct gttaaatgac cgaccagacc gccaatattg taggcatcag tcgtttcata
    18961 ggtattgaca attcttccct tgaaactgct ctctgcgatg cttgattggt ctgccttagc
    19021 caacaaacca ccgacaccac gttctccagc cagaacacca tcaacatgaa cttgtttaat
    19081 ctttgtgcca ttcgtagctt catttgccag tgaaccaata tcatttttcc ctgaaatagc
    19141 aacatttttt agactcagtt tttctactgt agcaccactc aagttttcaa acagaggttt
    19201 tttcaaatta tagatagcat aattcttgcc atctttttca ccgattaaac gaccagtaaa
    19261 ggtgtccttg atataggatc tttcatcagg accaagctcc acttcgttag cattcaggct
    19321 ggccgctaaa tgataggttc cagagggatt ttggtttata gctttgacca ggttgctaaa
    19381 ggaagtaaag tttgtatttt cctctttagc cttcttatcg aggtagaagg tgaaattgtc
    19441 gacatattta ttttctagtt cttgctggag tttctcagct ttggctgtga ttttataaac
    19501 tgactgccca tttcttttct cttcggttat tgaagctact ggtatataga catctttaaa
    19561 tgctgaagat tttaccttga caaagtaagt atccgtattc tctggaattc catccaatga
    19621 aacatgttgt ctgtaggttc cattcgtctg actatacaac tcaatatcag aaacatttct
    19681 taattcgagt tttttctctg gttctgtttg tccattctct gatgttgtat tacctgaatt
    19741 ttctggtttt gttgcagttc cgtttttttc tggttgattt gattcttcaa ctggtggttt
    19801 tgaatcacta ggtttattgg atacttctcc agtattttcg ttagctattt tcccagagtt
    19861 tgtttgtgtt tcttctgcag gttgaactgg tttttctgtt tcttgatttg aggtaccttc
    19921 tactgtgcct tcatttggat ttactggaac ttcttctaca gttttttctg aattttcatt
    19981 tttagagtca ttatgttctg gtttatttga ttctccaact gaggttgtcg aatcactagg
    20041 attactggac acttccccag tattttcgct agatgtatct ggtgatactt tctctgaatt
    20101 cgttgttgat tcttctgcag gttgaactgg attttctgct tcttgaattg aggttccttc
    20161 tgtagtacct tcatttggat ttactggtgt ttcttctgtt ggttttactg gaacttcttc
    20221 agttttttct ggaccttgtt ctttggtctt ctcaaccgga gtttcaggtt ttacttgctc
    20281 aatattaccc ttatattctg gcaatggggc tacctgctct ggttcacctt tatcacttac
    20341 cacagtatct ggcgactctg gttgaacctc agtctcacct ttgtcggtca caactgcttc
    20401 gggtaatgtc ggttgaactt ctggttcgcc tttatcactt actacagctt cgggcaactc
    20461 aggctgaatt gcgggttcaa caatagctcc agactgtacg tccttatgtt ctacaccagt
    20521 ctcaggttgt tcctttataa cttgagtttt tttagtacct ttttcgacta ttcttggact
    20581 aggcgcagtc gttgaagttg aaacaatttc tcgcgaaact tcttccttgt ttacagagaa
    20641 tattctgacg atttcaactt tcttacctaa tttaccttct tgttttactc ttacagttcc
    20701 ttcagctaaa tcaggatttt cttgaatttc ttcttgaaaa tctatttttg tctctatagt
    20761 ttcctcacga tataagagtt caggtttgtt caattgacct gataaaactt catcctgtgg
    20821 atttaatgta tttaccccag tcttttcttt tggagaaatc ttctcctctt tcttcgtttc
    20881 tagattctta tgttcggcta attgttcttg agaatctgaa gattgtttct cttcttttct
    20941 tggattgatt aattcagtag agaaaggttt ttcaactact tgaacttctg tcggcttagt
    21001 tgaagaaaca ggtgtttgtt cctgaatagc ttgtactgtt gatggatggt ctacaaaatt
    21061 tggtgtaaca ttataatcca ccttttgttg ttttgtagga gtggctgctg atttttcttg
    21121 attacttact tcaaaatcag aagtcgtttt tccctctttg atatatccaa tataagtgta
    21181 acctgaaatc tctttaggaa gaggtaattt ttctccagag gtcaattcat agtccgtatt
    21241 gtaatttagc aaaagatgat tttctaaagc atggactgaa actaagacac catttcccat
    21301 tcccgcaacc aatactaaat gtaataccgt tttattctta acctttttct tggaaacagc
    21361 aaaaattaaa attcccagag cagctaagct agcaccagca actagggctt gcctctcatt
    21421 cttgcttcca gtatttggta attccgccag ttgattttga gaatttaact tataaacaag
    21481 ataataagtt tcatcatcat tctccacgta tgtcggaata tcatagacaa gctgcttctt
    21541 ttcttctgat gatagctctg aatctgccac atatttatag tgaactcccg cagtttcttg
    21601 agcatccaca gatgaactag ctaatacaga cataaaaaat aaacttgaaa tcgttgcaga
    21661 tacaagtcct actgataatt ttctaaatga aaaacgctct tgtttttcac caaaatactt
    21721 ttccattatt cctccttgaa ataaaattta tatatgttac aaagaccttt attatattag
    21781 tgtattatct attatctata gaaaaggcag tataccttaa ttatactctt aatttacaaa
    21841 aaagtcttaa aattgagatg cgctttcata ctttgtttta tattatttgg gggtacaata
    21901 acacctacca tgaaatttac acggtaggtg ttactcatat cactaatcgt tctaaaaatg
    21961 gtttgaggca gttgaggaga attccttcta tccagcttcc ttgtgctgat gagcgatggt
    22021 cttcctgcag gctttttttt agaaaatctc ggacttgttc tggtgcgatt tcaaattcaa
    22081 aggctttcat tttatagaaa aagtcgatga gatgatctga caggtattca gttgaaaagg
    22141 gtacttcacc actttttcga tattctaata agagtctaga aaatcgagct ttttcttcag
    22201 gaagctcacg aaaataggaa ttgaggatcc aagtctgctt ctgttttctt tcaattggat
    22261 cctgactggc aattcgttgg tctttttcca gctctttttg gtattgtttg gccttgatag
    22321 ctcgttctgc tctattttta ccaaaaagaa ttttttccca cttgcgttct tcttgagtca
    22381 gggtctctgt aaagccaaag taatcttgat aagcacgctc tgcgggtccc atggctagaa
    22441 ccagattgtc tgcatattgc ttggcgattt tatccctctt cttgcgttct ttctctgcct
    22501 ggatacggag ttcttgttcg tagtcaattt tctccttgcc tagcttgaca aggtagagtt
    22561 ggtcatccga tttcccaagt aaaaagggtt tgatacactt ttcaaggact tcttccatcc
    22621 gagccttttt ctttggttcc gccttggtcc aacttcctcc ctgaaagact tctaggaaaa
    22681 gctggtagtc tctctcaggc gcaaattgat tgccacgatt gggtttgaaa acaccttttt
    22741 cccagagcca ttttagaagt cgctcgtcaa agttactttt attgaccttg attttttcct
    22801 ttttctgagc ttttctggtt agattttcaa cctttctgag cagtttttct tcctcttcca
    22861 attgctggtc aagggacaat cgatgaaaat gacgaacaca gtcgctacca attggaaaga
    22921 ggcgttggcc tgtgacaccg ttaaagagtt cataagcgta tttgatggca tttccacaga
    22981 cacaattgct acggccgata ccgttaaaaa taaaggaaac ttcattccat tccttggtag
    23041 cttgttccca agtatccgct ttcgaagcct gtaaaactgc atcgtgcagg gattttctaa
    23101 ctggaagtgt catgaggtct cctttctaat actcaataaa aatcaaagag caaactagaa
    23161 agctagccgc agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca
    23221 gtaaccatat atacagcaag gcgaagctga cgtggtttga agagattttc aaagagtata
    23281 agttatactt ttacaacttg aacctcgtct ttaccgagta aaatcaagta tttttcaata
    23341 ttttcaatcg aataggctcg tgataaagcc tcttcgtata gagctaactg accacgatag
    23401 cggtctacga gttgacttgg ttcatcatag cggtctgtct tgtagtcgaa cagaacaatt
    23461 ttgttttcgt aaagcagata gccatcaagg ataccacgga caacaaagtc ttcctgactc
    23521 ttttggtctc gtttgagcat ggagaaaggt tgctcgcgat aaagatggtc ggtattagca
    23581 agaatttcct gaccgagtac tgtgtcaaag aaagcaagaa ttttatcaag attgatcttg
    23641 tctctgacag cttggctagt ttgaacttgt ttgagtgttt ctgttaggct agcaagggtt
    23701 agttgctggc tgaggtcaat tctctgcatg agttcgtgag tagcactacc aatctcagct
    23761 ccagttacct tttctttggt tgaaaaatct ggcaaatcga agctgatttt cttgcctact
    23821 gactgacctt gaccagcaat ctcgacacct tccatatcca taactggttc gtagaatttc
    23881 ttgatttgac ttggggtttg aacactagga agttcaatag ctgcgcggtg aagagtatta
    23941 taaacttcca cctccttcag catttccaga gcttctttga tggtatctga ctgacgattg
    24001 tctgcttggg agctatcttg gagaggactc ttggtttcca actctccgat agcttctctg
    24061 gtcaactgat cttcgccaat aaaacgataa ctaaagttga gcttgtcctt agtaaacact
    24121 ttactgatag cccaaagcca atcttggaaa ttccgtgctt gcagtctagt attgctattt
    24181 agtttcccat ttttggctgc tgggtattcc ttggattcca gcttttcacg agaacccttg
    24241 ccgacaagat agagcttttt ctcagcccgc gtcatagcaa catacagcaa acgcatctgc
    24301 tcagaatagc ttgctagctg taattcctct tcgttctgcc tataggtcag actaggaatg
    24361 gagagtttga tggttttagg atagtggtct tctactgccc ctgtctccat cttggcaata
    24421 tatttgacac caagaccatt ctgacgactg agaatgactt ctgacataga gtcttgcttg
    24481 ttgaaatctt gatccatatt gaggataaag acgtaaggaa actccagccc tttactcttg
    24541 tggatggtca tgagctttac tgcatctttt ggcggtgcga cggccacgct tgccaaatcg
    24601 tgctgggctt ctaagacttg gtcaatcata cgaataaaac gcgacaaacc tttgaaattg
    24661 ctcttttcaa attgatcagc acgcagtgct agggcataga gattggcctg cctagcagga
    24721 ccattcggca aagccccaac atagtcataa taaaaacggt cgttgtaaat cttccaaatc
    24781 aagtcataga gagagtgggt tttggcatac aagcgccaag aagctaggat atccatgaat
    24841 tgttttagtt tttcagctag agctgtgtga atcaagcctt tttgactact tgccattttt
    24901 tgtgcattga ccagtttctc atagagattt tcgtggactt tatcctctgc tttctgaagg
    24961 gacaaacgtg ctagctcatc ctcatcaaaa ccaaacattg gagacttcat aagggcaacc
    25021 aaggcgtagt cttgcagggg attgtgaatg acacgaagag tgtctagcat gacttgcact
    25081 tctagggatt ggagataatt gttttgctct ccgtcagttt tgacaggaat cccgtactca
    25141 gacagggcga ggagaatctg gtcattacga ctgcggctgg aggtcagaag ggcaatttcc
    25201 ttaaaggcaa cacctttttc ttgatgaagt ttcagaatct ccttgataac taagcgcatt
    25261 tcgcctgtta gtttcgtttc tgtttgactc tcttcttcct cacctgtatc gtccttgtcg
    25321 tagaggagaa attctgcctt gttgtctgga ttgggagtca gtttggtatt ggcaaaaaca
    25381 agctggtgct tgttatcata gttgatttcg ccgacctctt ggtccatgag acgttcaaag
    25441 acatcattgg ttgctgacag cacttctgaa ctactacgga aattttcctt gaggagaatg
    25501 agcttgcctt tttggggatt ttgcgcatag cgttggaatt tctcattgaa aatctgcggg
    25561 tctgcctgac ggaaacgata gatggattgc ttgatatctc ccaccataaa gcgattgtgg
    25621 ccattagaca acaattccag catccgttct tgaatatggt tggtatcctg atactcatcg
    25681 accatgactt catggaagcg ctcctgataa gactcacgaa cttgtgggaa attctctaaa
    25741 atctcaatgg tgtaatggct gatatcagcg aattcaaagg cattttcctg gcgtttgcgc
    25801 tgacgataag cctccacaaa atgactcata aaggtttgga aggttttagc tagttcccat
    25861 gtgtcttgat gataacgttc ttgatagtcg agaatggtta tctggtctga taattgtcct
    25921 agtttagcaa actgggtctt tctctcttcg ttgtaggcat cagccagggg cttcaaatca
    25981 gccttacgac tggcattagt cagagctcga ccgtttttct ccttagagat ggcgacaaca
    26041 cgcgcaagca ctgcctgata agcctgacta tcggactcct gatttaggga gccaatttca
    26101 tccagaatta actgaacatt ttctaaatag gcagcctttg caaactcctt ggcatcgtta
    26161 tccagatggt aacggaaaaa gctttccaaa tcccaaaggg cttgtttgat ttgctcagtc
    26221 agtttttctt tttcactggt aaaatcagct ttctcaaagc ctttgaggaa agattcactc
    26281 aaccactttt gaggattact ggtggattgg aggaagtcat agattttata gacctgctgg
    26341 cgcagacccc gttcgtcctt gccacgccca gcaaagtttt tcagcaaatg actaaaggtc
    26401 tctttctgtt taccttggta atgcgcttca aagacctcat gaaagacttc gttttcgaga
    26461 agaagttgct cgctttggtt ttgtaaaata cggaaattag gtgcaatatc aagcagataa
    26521 ccatgtttgc caaggaattt ttgtgtgaaa gagtccatgg ttccgatggc agcgttgggt
    26581 aggtctgcca actggcgacc caagtgttgt ttgagatcga catcatctgt ttcttggatt
    26641 ttcttgctga tttttttctc taaacgttct ttaagttcag ttgcagcctt gacggtaaag
    26701 gttgagataa agagttgaga aatttcgaca ccacgcgcca attggtccag aatgcgctct
    26761 accatgacaa aggtctttcc agaaccagcc gatgctgaga ccaggatatt ctgaccagaa
    26821 gtgtagatag cttcgatttg ttcggcagtt ttcttctgtt ccttgctcga atttgcttct
    26881 gcttcttgca gtttttgaat ctcctcctca cttaaaaagg gaataagctt catcgattta
    26941 actcctctct tattttttca aaccaagctt gcttgagttt ttctccgacc agacgcttgc
    27001 catcagctag gtccaacttt tctaggaaac gggcttggcc cagatggtaa ttggcttcaa
    27061 agcctgtaat agcctgatgt tgctggacgt atggggcaat gcttctgcca ttttcagtat
    27121 aaggattgat ggcgaaccgg cctgctaaaa tcttctcagc agctttcttg taaagatagg
    27181 cattgtagtc cagtaggagc tgaaattcct catctgtcag ttgattagcc ttgtttttgt
    27241 tataaaattc gcctaaataa ctgctttctt tttccaagaa gagcccttgg tatttcatag
    27301 atttgctggc ttctaccact gctcctgcca gactttttac cgccatcaga gattggacag
    27361 gttcagccat ttccaagtac atggcgccga aaaagttctg ctccccttct ctttttaggg
    27421 cagcaagata ggttggtaac tgagaattga gcccattaaa gaaatgagga aactggaact
    27481 gagtcagact ggatttgtag tctactactc ctatcgctcc attagctttc aaacggtcaa
    27541 tccggtccac cttgcctcgt acaaagacac tgcgtccatt gtctaattga ataaaggctt
    27601 ggtcttttcc accaaaattt gcttcttctt tgatggtttc gatggctgga ttgtgtcgga
    27661 gaatatgtcc agtcgtccgt gcaacatcaa gcaaaacttc cttggtaaac tgggcttcca
    27721 aactttcttg ataaatagct tcaaattcgc gttcttgact ggtttcttga atagcttgtt
    27781 ctagacgttg gtcaaaggaa tcttcattag gcaactgtaa ggcgcgttca aagatacgat
    27841 gcaagaaatt cccgtgacta cgggcatcag gacgcaaacg taattcctcc tgcaagccta
    27901 aaacgtagcg taggaaataa ctgtattcat tgcgataaaa ctctgtcaaa cccgacgtag
    27961 acaggtaaaa ctcctgtttg gcaggataga gagcttgcaa ggtgtccttg gctaaggtct
    28021 tgctgcttgg actggttggg atagctggat tttccagacc ttgcagatct agttttttac
    28081 ctatgacacg cgacagaacc ttgacaaaag tcaaatcttg ctcagtatcg ctcatctcac
    28141 cctgctggtg ataggcaacc agactagaca aaagactgtg ataggacccc atatcctcct
    28201 tagacagtcc tttgtgattc atcctcttct ctctccgcct aaatccaaaa tggatcaact
    28261 cttgaagata ggcagattcc ttactttcac tttcgttaaa aaggcttgga gccgacaaga
    28321 acaactgctt acgagcagaa ttgaccaagg aaagcatagt gtagcgattt ttcttgagat
    28381 tttcactgct ggcaatcagt aattgaacgc cttcttcggt cgcttggttt agattttgcc
    28441 tttcttcatc tgtcagaaga ctggtgtttt gagaaatttt tggtaaattg tcctgagtta
    28501 gtccaatagc atagacaaag tcagcagtca atggtgcaat caaatcgtaa ctctgcacca
    28561 gaacagtgtc cactgttgct ggaatggtac ggtattggga caaactcatt ccagaatgga
    28621 gcaaggctag gaagtcttcc agactaacct gtgaaccagc aaaaacagtc gcaaattgtt
    28681 ctaaaacatg gcagaaagcc ttccaaactt cggcttgtct ttcctgttct acagcttcca
    28741 aagtggttgt caaatcttgt aactgcttgg tcacagctcc ttcttttaga aagacactcc
    28801 atttttgtag gaggttttca gccttttgtt ttcggctggc aaagagggtt tcaagaggtg
    28861 ctaaaattct caggcggagg acattcaaac gctcaagatt aaattttcca tggtgggatt
    28921 tggtgaagat ttgctgaaag gctggcaagc cattgatacc aagatagcgg atatattgct
    28981 caaaagcatc aatatcagac tgactgaggt cagtatacaa atcagttcta agaagattaa
    29041 tcaaatcctc ctgacgaaaa cggtaacgtt ttaaagctaa aatagactcg acaaactgag
    29101 tcaagggatg atgagccatg gcttcgcttc taccaagata aaaaggaatc tgatactggt
    29161 caaaaatggt tttgagagat aactggtaag aagctacatc ccccaagaga atacgaaaat
    29221 gcttgtagct caggtctgag ttctcatgta atttctgacg aatgctacgg gctactagct
    29281 ccaactcctc cttttgcgtc aaacaagacc agatttgtaa attttcacgg tctttctcat
    29341 cgacatccaa agcgagttct gaaaagtcat aagaagactc caacaaacga gaggccttgt
    29401 caaaactatc catcttctca tgagtttgag aacagtcctg agcaggcgtt tggtatttag
    29461 aagccagatg atggagaaat tttacgctgg cttggtagag attgccctcg ctaaaaggac
    29521 tggtataggc tttcttacta gcataagccc cgataacaat ctcaacacct ttgccgtgaa
    29581 gtaagtccac aacccgctct tcctcagcag aaaaacgagt aaagccgtca atgaccaagg
    29641 tgatttgatt aaaatcacta cttaccttgt cattctcaat agcctcaatc aaatgggaca
    29701 actgacttcc ctgggctaac tgaccttgat taagataggc tgttactttc tcaaaaatca
    29761 agagtaaatc cgtcctctta tcctcatctg ttaaattctc caagtccaaa aaactcatct
    29821 gagatttggt catctcatgg taaagctcaa ttaactgctg gatcaattga ggatcctgct
    29881 taatagcgcc ataaacacgc aagtccttgg gatcgagttc ggcaaggcat ttgtaaaagg
    29941 ccaacccaag accgatatca tcaagagtag ttttaactgg taaatcattc aggaccagat
    30001 aacgagccat ttgagcaaag cgcgtgacgg taatagaaaa agaagcctgc tgggacaagc
    30061 attccagcac ggcgcgttcc ttttcaaaag aaagagagtt gggggcaatg tagaagaccc
    30121 gcttgccagc tgcaactagc tcttctgcct ctcttgttag aatttctgtc aaagaagttc
    30181 gaatatcagt ataaagtaat ttcatctcag cctcgttgga atttttcatc accctatatt
    30241 ataccatgat tagcctcgta aatctgttaa aatatttagg ccatcctttc ttttcttcat
    30301 catctgctaa atcttaaata cttagcttta cttgtattag atagaataag tctggctact
    30361 gaaaatcaca taataaaaaa gcctcggtaa caagactttg agttttatga ttgtttctta
    30421 ggtacggaat acacttcaat gtgttgtccc agtatcttaa tgtcgacggg tagattgtct
    30481 gatttatcgc catcaacatc ggactctaat tcgatatcag aagaagtttt aatattacgt
    30541 gcctttatat attcaatatt cttgatagaa tgattgaact atagtaaatt gaaactataa
    30601 tagtacatcg tg
//
LOCUS       DAVLUM010000024        30233 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLUM010000024 DAVLUM010000000
VERSION     DAVLUM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.024"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..1532)
                     /locus_tag="VYN42_000885"
     CDS             complement(<1..1532)
                     /locus_tag="VYN42_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1461983.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKEIMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIVGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQAKFSNEGIDKISDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDVFKKAIAYEFDALKEEYISLILDDKAGAGG
                     SRTSGGLSSAADAILGVTESAQEVALEKALQNADLDFDHKAGLLRQEISDGIELAKAK
                     AEEVKQELSDTINQRFNSFDNGPLKEAKRRAEEALRNAGASSLLAQEAKRIGLDSVAR
                     LEEFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQVEAEIAKQVEALVQTKKELSGA
                     STL"
     gene            complement(1533..2255)
                     /locus_tag="VYN42_000886"
     CDS             complement(1533..2255)
                     /locus_tag="VYN42_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1461984.1"
                     /translation="MIKHNELVIDGVRTSSFPFKVIVHDSPSIALGESKTALLEHGGI
                     SGAIVQTNKHRELVKKSYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVTDLEEVQPGLYMTKATFTCHPTKYFKATDTQRLTRSGTLNVQGSALAFPKITIVG
                     QSVVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            complement(2252..5011)
                     /locus_tag="VYN42_000887"
     CDS             complement(2252..5011)
                     /locus_tag="VYN42_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEV1461985.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANRM
                     EAELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAEALDLTSRATRAAADGAAFYDKSIESVTESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFSSLPAPVKDFVVILGTV
                     VTAVGVIAPIFLSLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILEVINAVVSEISNFVMSIFGTVVAWWTENQELIRASAETVWN
                     AIYTVISTILEILGPLIQAGWDNIQLVITTAWEIIKTVVETAINVVLGIIQAVMQIIN
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRKTQL
                     RAGVT"
     gene            complement(5289..5708)
                     /locus_tag="VYN42_000888"
     CDS             complement(5289..5708)
                     /locus_tag="VYN42_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461986.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSENPHIKPYEQFFMEME
                     VFPIQEVGPVLMEMLNASMTTKKHQMNQNQLAKKSSQ"
     gene            complement(5720..6298)
                     /locus_tag="VYN42_000889"
     CDS             complement(5720..6298)
                     /locus_tag="VYN42_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1461987.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIDLTL
                     DTKGETTTIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            complement(6310..6633)
                     /locus_tag="VYN42_000890"
     CDS             complement(6310..6633)
                     /locus_tag="VYN42_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461988.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPNLPYLVYYESIPAINA
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            complement(6630..6989)
                     /locus_tag="VYN42_000891"
     CDS             complement(6630..6989)
                     /locus_tag="VYN42_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV1461989.1"
                     /translation="MSLTSDLANEIAKAMAEYSAEVEDKIDLIAEDVVNEAVTELKAT
                     SPKRHGKYARNWRFKKNAKGSYVIYNAAPTYRLTHLLENGHVLRNGGRSRAFPHIKPV
                     EEKVKENFEKRIKEIGK"
     gene            complement(6986..7285)
                     /locus_tag="VYN42_000892"
     CDS             complement(6986..7285)
                     /locus_tag="VYN42_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEV1461990.1"
                     /translation="MWNHEITLISKEVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            complement(7272..7553)
                     /locus_tag="VYN42_000893"
     CDS             complement(7272..7553)
                     /locus_tag="VYN42_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461991.1"
                     /translation="MDNVQLLELLKLKLGIATKLRDKPLEKIIEAVKTELEDNLGVLL
                     DLDSSEDQMFVVDFAAFRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            complement(7556..7825)
                     /locus_tag="VYN42_000894"
     CDS             complement(7556..7825)
                     /locus_tag="VYN42_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461992.1"
                     /translation="MVYKVIRPFKDLRDPKKHCYKVGDNYPRVKHKLDKEFAETLLNG
                     ANSAGSIFLMNVEDKDMSKDDTLTTEVEKEETKVVDGKPEEGDEE"
     gene            complement(7837..9003)
                     /locus_tag="VYN42_000895"
     CDS             complement(7837..9003)
                     /locus_tag="VYN42_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEV1461993.1"
                     /translation="MNKALIFGARMRAKATKVVELEETIEELNKRSVVELEKLDRAKN
                     DEEVLAVEKTVDGLQREIEEKEAEKVQLENEIDELDKQIKEQNRKAPTPGKMEERGGK
                     TLGQREAFNHYLRTKEARADGFKSAEGEAIIPVELMTPKEAKQDKTDLTSLVNIVNVK
                     NASGKWSVVKLTDQAMNTVEELEENPELAKPTFTKVNYEIKTRRGHLPVSQEFIDDAD
                     YDVMGLVAKQTKNQERITKNKEIAKVLKTATSKSAAGLDGLKDILNVELKTYYNATIV
                     CTQSMFAALDKIKDKDGRYMLQTDITSPTGYKFAGRVIVVYPDDIIGESKGDLKAFIG
                     DVGEFATLFDRAQTTVKWQDDKIYGQYLATANRFDVVKVDGDAGFYVTYTDAVL"
     gene            complement(9000..9575)
                     /locus_tag="VYN42_000896"
     CDS             complement(9000..9575)
                     /locus_tag="VYN42_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEV1461994.1"
                     /translation="MQKRNSYRATQFQTREEESGDLVLSGYFIKFDEETELWRGYHEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFKL"
     gene            complement(9559..10761)
                     /locus_tag="VYN42_000897"
     CDS             complement(9559..10761)
                     /locus_tag="VYN42_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1461995.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDILYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            complement(10779..10997)
                     /locus_tag="VYN42_000898"
     CDS             complement(10779..10997)
                     /locus_tag="VYN42_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1461996.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            complement(11005..12735)
                     /locus_tag="VYN42_000899"
     CDS             complement(11005..12735)
                     /locus_tag="VYN42_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV1461997.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            complement(12728..13120)
                     /locus_tag="VYN42_000900"
     CDS             complement(12728..13120)
                     /locus_tag="VYN42_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HEV1461998.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYVDMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            complement(13257..13577)
                     /locus_tag="VYN42_000901"
     CDS             complement(13257..13577)
                     /locus_tag="VYN42_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1461999.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            complement(13954..14496)
                     /locus_tag="VYN42_000902"
     CDS             complement(13954..14496)
                     /locus_tag="VYN42_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1462000.1"
                     /translation="MEFVSPIKDNDDIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            complement(14684..15085)
                     /locus_tag="VYN42_000903"
     CDS             complement(14684..15085)
                     /locus_tag="VYN42_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1462001.1"
                     /translation="MKKLSDEDLKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     SVGISKPTETIAVRIADDPTLKFLEGFKAIINKLLINLVDEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAILKGEL"
     gene            complement(15222..15632)
                     /locus_tag="VYN42_000904"
     CDS             complement(15222..15632)
                     /locus_tag="VYN42_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462002.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTYIGGMP
                     AVYLKGFGDGYAWTEYEEIIGNVYENPELLEVNE"
     gene            complement(15644..15922)
                     /locus_tag="VYN42_000905"
     CDS             complement(15644..15922)
                     /locus_tag="VYN42_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462003.1"
                     /translation="MKRLGIIIGAVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQAL
                     GMDALLSFIWPVLSSKKESEEDYSYAVKSSISKIITCAFLIWLASLFI"
     gene            complement(16024..17106)
                     /locus_tag="VYN42_000906"
     CDS             complement(16024..17106)
                     /locus_tag="VYN42_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1462004.1"
                     /translation="MKFLDLFAGIGGFRLGMESAGHKCIGFCEIDKFARESYKAIHNT
                     KGEIELHDITAVSDESIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRREHTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAIKSNTIKQFGVLQPNFNQCGVVYETDGIAPTIRAYQGGGLEPKIIQRG
                     HGYNKGGEHNIAPTLTSNSYHENNHLSDGFRIRKLTPRECWRLQGFPDWAFDKAQEVN
                     SNSQLYKQAGNSVTVNVIAAIAKELS"
     gene            complement(17137..17424)
                     /locus_tag="VYN42_000907"
     CDS             complement(17137..17424)
                     /locus_tag="VYN42_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462005.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEERV"
     gene            complement(17424..17954)
                     /locus_tag="VYN42_000908"
     CDS             complement(17424..17954)
                     /locus_tag="VYN42_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1462006.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVADWIEVCKEHLTTSLYTAMTPNFMKENNQSFDLILWIKKASNQDLFARAW
                     LDGYEVEKEKRYLVKIKGNIKENMLVYGELLERYFFTKSFSLDDAIYSHTRKELENAK
                     IGWVFDCEGFEIEEVE"
     gene            complement(17956..18273)
                     /locus_tag="VYN42_000909"
     CDS             complement(17956..18273)
                     /locus_tag="VYN42_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462007.1"
                     /translation="MMEELKRKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGN"
     gene            complement(18441..18608)
                     /locus_tag="VYN42_000910"
     CDS             complement(18441..18608)
                     /locus_tag="VYN42_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462008.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            complement(18693..18911)
                     /locus_tag="VYN42_000911"
     CDS             complement(18693..18911)
                     /locus_tag="VYN42_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462009.1"
                     /translation="MLELYFVYNGHCKFYLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGK"
     gene            complement(18921..19595)
                     /locus_tag="VYN42_000912"
     CDS             complement(18921..19595)
                     /locus_tag="VYN42_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1462010.1"
                     /translation="MMKFLNGDCMDIMKQYPDNYFDLAIVDPPYFSGPEKRKFYGRKI
                     SPIGVSRLYGEISEWKIPNRDYFDELFRVSKNQIIWGVNYFDYSFGSGRIVWDKVNGQ
                     SSFSDCEIAYCSYHDSTRLFRYMWNGMMQGKSISEGHIQQGNKALNEVRIHPTQKPVN
                     LYLWLLQTYAKEGDKILDTHVGSASSLIACGELGFDYVGCEIDKSIFNLAQQRLDAYE
                     KQLKLF"
     gene            complement(19804..20574)
                     /locus_tag="VYN42_000913"
     CDS             complement(19804..20574)
                     /locus_tag="VYN42_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1462011.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(20568..20726)
                     /locus_tag="VYN42_000914"
     CDS             complement(20568..20726)
                     /locus_tag="VYN42_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462012.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(20714..21520)
                     /locus_tag="VYN42_000915"
     CDS             complement(20714..21520)
                     /locus_tag="VYN42_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1462013.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNKNRLDK
                     DKNKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAI
                     NSGKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            complement(21513..21809)
                     /locus_tag="VYN42_000916"
     CDS             complement(21513..21809)
                     /locus_tag="VYN42_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462014.1"
                     /translation="MEELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLLVKE
                     YLTDYEKLAKDYRYVTLKNKLLKIEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            complement(21825..22145)
                     /locus_tag="VYN42_000917"
     CDS             complement(21825..22145)
                     /locus_tag="VYN42_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462015.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPQGLRPEPLALPEPKQSA
                     IRLL"
     gene            complement(22231..22488)
                     /locus_tag="VYN42_000918"
     CDS             complement(22231..22488)
                     /locus_tag="VYN42_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1462016.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(22502..23212)
                     /locus_tag="VYN42_000919"
     CDS             complement(22502..23212)
                     /locus_tag="VYN42_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEV1462017.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYSKARNAITLH
                     VDEEDALKQGIPTSGGTQDMLIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRKQ
                     GGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAQSLLKKRKAR
                     VVACLGGIDSPAYADKVFAQSVFRQAEIDFKDHFNISRYDLLPKKHADAALAYWMTWE
                     PSTNTKMKIMKLNSFDDV"
     gene            23266..23691
                     /locus_tag="VYN42_000920"
     CDS             23266..23691
                     /locus_tag="VYN42_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462018.1"
                     /translation="MDYQILIQPAISVILAIISGLWSYIASKANNKAEIEKQAKEHSH
                     IVEKLEKEFHYQIDTLKQQHTLELEKVKQAHELRLQELEKVSQIDTETDKAMKMNDLI
                     YKTFTGEVDLDKALKLADKANNHKQKLNKKFIQKTSKKS"
     gene            complement(23686..23847)
                     /locus_tag="VYN42_000921"
     CDS             complement(23686..23847)
                     /locus_tag="VYN42_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462019.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDRKKRINEYKKIQDDEL
                     ERIRNKFNL"
     gene            complement(23858..24055)
                     /locus_tag="VYN42_000922"
     CDS             complement(23858..24055)
                     /locus_tag="VYN42_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462020.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            complement(24072..24275)
                     /locus_tag="VYN42_000923"
     CDS             complement(24072..24275)
                     /locus_tag="VYN42_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1462021.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVTSSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            24330..24812
                     /locus_tag="VYN42_000924"
     CDS             24330..24812
                     /locus_tag="VYN42_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462022.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            25118..25486
                     /locus_tag="VYN42_000925"
     CDS             25118..25486
                     /locus_tag="VYN42_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462023.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            25486..25719
                     /locus_tag="VYN42_000926"
     CDS             25486..25719
                     /locus_tag="VYN42_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462024.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            25719..25982
                     /locus_tag="VYN42_000927"
     CDS             25719..25982
                     /locus_tag="VYN42_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1462025.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            25995..26375
                     /locus_tag="VYN42_000928"
     CDS             25995..26375
                     /locus_tag="VYN42_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1462026.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLAPE
                     QQIQVALHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEVMVKEEYLALVN"
     gene            26413..27225
                     /locus_tag="VYN42_000929"
     CDS             26413..27225
                     /locus_tag="VYN42_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1462027.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            27399..28547
                     /locus_tag="VYN42_000930"
     CDS             27399..28547
                     /locus_tag="VYN42_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1462028.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(28789..30075)
                     /locus_tag="VYN42_000931"
     CDS             complement(28789..30075)
                     /locus_tag="VYN42_000931"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1462029.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
BASE COUNT         8697 a         6855 c         5054 g         9627 t
ORIGIN      
        1 agggtacttg cgccagacag ttcttttttg gtctgaacaa gtgcttcaac ttgcttggca
       61 atctcagctt caacctgtgc ttgcttcggt cgaatatcat tcacgatagt ccgtttcaga
      121 gcgtccaagt cacctgacag agccgtttgt gcgctcgtag tctgcgactt aaactcttca
      181 agtctagcga cagaatccag cccaatccgc ttcgcttcct gagcgagtaa gctgcttgcg
      241 ccagcgtttc tcaaggcttc ttcagccctg cgcttagctt ctttcaatgg cccgttgtca
      301 aagctattaa agcgctgatt gatagtgtca gacagttctt gcttgacttc ttccgccttg
      361 gccttggcaa gttcgatgcc gtcagaaatt tcctgtctaa gcaatccagc cttatgatca
      421 aagtctaagt cagcattttg aagagccttt tcaagggcaa cttcttgtgc agattctgtt
      481 actccaagaa tggcatccgc tgcgctagat aagccaccag atgttctaga accaccagct
      541 cctgccttat catcgagaat cagagagata tattcttctt ttaaggcatc gaactcataa
      601 gcaatagctt tcttaaatac atcaacatta tgtttccagc tcttgagatt gaccgtatca
      661 cccatgtgaa caacttgccc atcaagttca taagcttcaa tcttgatagc gtcagagatc
      721 ttgtcaatgc cctcgtttga gaacttagcc tgtgcccact tctgcaactc ttcaacggat
      781 tttgcgttgt tgttctcata ctctttttcg tttatgtaag gataagaatt aataagagga
      841 ctatcaacag tcactctgat agttgtttcc ttttcagcac cttcaggttt aaaagtcgac
      901 tttgcgtgaa ttcttgtgac aacattctga ctgttttttg tgcgttggta gttcttcaga
      961 tttttgtgcg ttgtaataac aacaccacga ttctccccac gactcttctt tacagtcatc
     1021 gcaaagttat cacgcaccag ctcgccttcc cacgttccga cgatactatg cttgccgtcc
     1081 agcaatacag agtacagggt ttctgtctca gtcgtgttga atgtcctacg gtcctggata
     1141 tcactgttga atgagaagtc tccaagagct gttttggtgt tttgtaccat gcgagaaaga
     1201 gccatgccac aactctgact agtcacactc atttgtgtga tagatcgttg catcacatca
     1261 tctgaaatgt gataggctgt gatttccaga tggtcattgt gctcaacagg tttcttaatg
     1321 cgaaatagct gcgcaccaag aacaggagtc ggcgctttta tcaacatatc ttcttggatg
     1381 agctgataaa taccagagtc ggaaatggga tatttcacag ttaaggtgaa atcaccattc
     1441 atgatctctt taacaatcgc cgaagtcgct tcatgaagtg gctccccgtt ccatcgaacg
     1501 gttcttacat ctttattaag tagataaagc aattatgccc acccccaaac cgtttcgatt
     1561 tcaatcgatt gaatacctgg gcctaaaaca accccaatat tcttaacttt cgctggatca
     1621 actgtgataa aatcccctga ccatttcact ggcttccctg ttgtcgtttt aaagctagga
     1681 ttgtcaggat tattaaccat cacaagcgat tctgagagtt tttcaagcct aatgacctga
     1741 ccagcgattg taaatgaagt ctcaacaacg ctctgaccaa cgattgtgat tttaggaaaa
     1801 gcaagagcag aaccttgcac attcagagtc ccgcttcttg tcaatctctg agtatcagtt
     1861 gctttgaagt attttgtagg atggcaagtg aaggtcgctt tggtcatgta aagaccaggt
     1921 tgtacttctt caaggtcagt cacattgacc ttatagcacc agagacgagt tgttttgact
     1981 cgctcgctct ctaaccagaa cttctcacgg ataaacagac tcataaattg gttcatctgc
     2041 tcctcagtcg gtttgactaa gtaaatcgta taagatttct tgaccagttc cctgtgcttg
     2101 ttcgtctgaa caattgcccc actgatacca ccatgctcca aaagagctgt cttgctctct
     2161 cccagagcaa ttgaaggaga atcatggaca atgactttaa acggaaaaga cgatgttctc
     2221 acaccgtcaa tcacaagctc attatgcttt atcatgtaac ccctgctctc aattgtgtct
     2281 tacgttgcaa ctcgtcagca atacgctgag ccacctcatc agcaatacga ctgatgtcgg
     2341 cttcttctct gacagtgttg ccagtaatgg taatgttaat ggttggtgaa gttccaccca
     2401 tagtttgagc gatacctcga ccgatggctc caagcgtttt gtcgttaagt ggcaatactg
     2461 cttcattccc agcttcacca ccaaccatta tgttattacc attcattcca aagatagttg
     2521 gtttcgtcat gataccgcct ttggcatacc attcgattcc aatacttgga acaccttgac
     2581 tcaaccaatc taatggattg gccgaaccac tcacgtaaaa gtgaggtagt gggatatgtg
     2641 gccagctgat gttgaagtta aacaatcctt tgatggcttc aatagctgaa gaaacagcat
     2701 cccttgcacc attgatagca cttgaaatgg tactcttgat accttcccaa acacttgaga
     2761 cagtactaga tatagcattt aacacatttg agacagtgtc cttgatgctg ttccagatat
     2821 ttgatacagt tcctgaaatg ccgttgagaa tatttgaaat ataactctgg atagctgaga
     2881 aaatagtctg aacaatgctt tggatagctt gccatacagt agagaatacc cccttaatag
     2941 tttcccaagc gcctgaccaa tcaccattga tgatctgcat aactgcttga atgataccaa
     3001 ggacaacgtt tattgcagtc tcaacaacag tcttaatgat ttcccaagct gttgtaatga
     3061 caagttggat attatcccaa ccagcttgaa tgagtggacc taaaatttcc agaattgtgc
     3121 ttataaccgt atagatagca ttccagacag tctcagcact tgctcgaata agttcctggt
     3181 tctccgtcca ccaagcaaca accgttccaa agatactcat gacaaaatta gaaatctctg
     3241 atacgactgc attgataact tcaagaatcg cattccaaac ggtcgtgacc gcatctcgaa
     3301 aaccttcgtt agtttcccag agatatttta caataacaat aattgcagca actgcagcag
     3361 caattgcaat agctgttcca ataattggca atgcggcaat tatcatttct ccaatagata
     3421 tttttaaaaa ctcagcaagg gcttgcaacg ataagaatat gggggctatg acccctacag
     3481 cagtcacaac tgttcctaaa ataacaacaa aatcttttac tggagcaggt aaggaactga
     3541 acagctcagc tacacctttc acaatcgttg ccaaggtttg aaaaacagga atcatcattt
     3601 ctagaagagg ttgaccaata gcagataatg cattggtccc agcttgtttc agattcccca
     3661 tcacgttttc taggccgtct gattctcttg cagcctgtcc aagagctcct gagagtttat
     3721 ttccgtcttc gaccatctga agcaaggtca attgcttctg cgcttcgctc aagtccttga
     3781 atgactttcc gtacaattta tttgcagcgg cattcctggt cgtttctgtt gcagaaatgc
     3841 caagagccgc atcgttagca aagtttccct tcaaaaaaga ttgtaagctc tctgtcacgc
     3901 tctcaataga tttgtcatag aaggctgcac cgtctgctgc tgccctagtt gcacgagaag
     3961 taagatccaa agcttctgct gtatccaatc ctgaagtttt tgcaaatgaa gccatctgag
     4021 tgaatgatcc ttgcaatcgc tctgggacaa tatccatttc ctgaccaata gcattcaacg
     4081 cttctcttgc ttgggtttcc atatctccga aaacggtagt aaattgagca ttactagctt
     4141 gcatttgagc agctgcttct aacgcttctt ttcctacttc cacaagcttt tctgaaatag
     4201 cactcaactt ctcactaaac tgttgaagta gttctgctct taaatttctt gagatttcac
     4261 ttaaactttc ttgagtgcta tcagcagcag actttgttcc tttcatctca tcattgagat
     4321 gattgaatgc tgtcttagcc tgatttagct ctgcttccat cctgttggct tgtgtggagt
     4381 tctcaccaaa ttctttttta gtgatttcca attgctgttc tagatttgaa atctgtttac
     4441 ttacaatctc agactgagca ccaatctttt tctgagcaag agcatttctc tcggcttcac
     4501 tagcatttga acccaaagcg ctttcttgca gtttgaatga acttgtcacc ttactcatct
     4561 ctgaagcaag ttgactctgc tcattttgca actcttttaa ttggttcttg ttgttctgag
     4621 tagcactccc attctcatta agcgcctgat tcacatttgc aagcttaccc tcatatcctt
     4681 ttaggacgtt ttgagtaact tctacttcac gttggaaagc acggtactgg tcagcaccga
     4741 tatcgccatt tttgaattgc tgttccacct gagactgagc ttgtctcaag gtttctagtt
     4801 tctctttggt cgtcgaaact tgcttttgca agacctcttg cttctgagtc aggagcgtta
     4861 cgttccctgt atcaaacttc aatgctttgt caatctgtct caactcctga cttgcatcag
     4921 tagcagcctt attgacattt ttcagcgcct tctgtaaggg ttgcgtgtcg ccatcgattt
     4981 caattttaat acctttgata tttcctgcca tatttcctcc tttctcaaaa aaatagaaaa
     5041 gcgctgagag aacttctacc actgataatg cagccagacc aaggaacttg gtctcagaat
     5101 cgctctctca gcactcattt ttctttaaaa accgtcaaaa tcagcttgcg tggctttccg
     5161 ttcgccaccc ttatcctcgc tccgtagatt cacataatcc gtctgataat ccagagccat
     5221 tccgattgaa atgtgcttta gatcatcaat agaaagacca gtttctttac agcaagataa
     5281 gtaggtttct actgtgaaga tttcttcgct agctgattct gattcatctg gtgctttttt
     5341 gtcgtcatgc tcgcattcag catttccatc aatacaggcc caacttcctg aatcggaaag
     5401 acttccattt ccatgaagaa ttgttcataa ggcttgatgt gaggattttc agatttagca
     5461 aaggtccaaa aaagacggtt gaaaaaggtc atgtcaaaat ctgacaacat cgaaatatca
     5521 atattagtcg ctgtcaattc cttgtcggtt tccaacttgt tcaattcatt catgaatgat
     5581 tgatttttca acatcgagaa caaatcttga aaataatctt ttccaaattg ttgcttgtaa
     5641 gcaataggag tatagccgtt ggtccccaac tcatactcct gatcaccaac caaaacgatt
     5701 ttacgcatag atcttctcct taagctgcaa ctgcagtagg ttcatacact ttcttgaacc
     5761 agttgtcata cgcatccttg tcatcagctg atgtgataga acgcttgaca actgtatcca
     5821 atggacgcgg gctagctttg aaactaagtt cacgttcgtt ggttgatgtc ccgttcttag
     5881 tttttgagcc aagagatggg cgactggcaa aacagtagta catcacatag cgagtcttgt
     5941 ttttgtcgcc ttcaaactgg aacatcattg cgaactctgt caagctcgca tctgcttttt
     6001 cagtcataac accagtttga gggtccttga tttcaccaag aatttttgtc gcaaattcat
     6061 caatgatgtg tgggatttta agtttaccct catatccttc gtttgaattc atgaaatggt
     6121 aatccttgtt gtctgctttg atagtggttg tttccccttt agtatcaagt gtcagatcta
     6181 ttgctccagg aaaacgaaaa acatcgccgt aagtgataac tccatctgct gcaagtgtct
     6241 tgataggtgc gatatgtaca ttttctaggc caaaggttac tttattttct tgagtcatgt
     6301 cattcctcct tagtatagat agactgtgta agacttgaca tagagtcttt cagtctcgat
     6361 aaatgtttct tcttgaactt caaaaaagag cttgtggttt gcccacagct cttccagacg
     6421 ttcttccaaa tcttcatcct tactctcaaa agccagctca actgtcacgc tcttaatctg
     6481 atgattaacc gtgttgtcag ctgcattgat ggctggaatt gattcataat agaccagata
     6541 aggtaggtta ggagcgtttc caattttaaa cgctcgataa gtgacaggca agtttgcctg
     6601 ttccaaaata gcagcaaagt ctgatagctt catttcccaa tctccttgat tcgcttctca
     6661 aagttttctt taactttctc ctcaacaggt ttaatatgtg gaaatgcccg actacgaccg
     6721 ccatttctca aaacatgccc attttctagt aagtgagtta aacgataggt tggagctgcg
     6781 ttgtagatga cgtatgaccc cttagcattt ttcttgaagc gccaatttct agcatacttt
     6841 ccatgacgtt ttggactagt cgcttttaat tccgtaacgg cttcgtttac aacgtcctca
     6901 gcaatcaggt caatcttatc ttctacctca gcagagtact ctgccattgc ctttgcaatt
     6961 tcattcgcta aatcacttgt taagctcatt tcaacacctc tgacaaagtc aactctaaaa
     7021 tttcagaatc aataggatag gttttcaaga tatgatattg cttgccttcg aacttcgcaa
     7081 gctcttgatt ctcatactca aaatttcgaa tctcaacgac caagctcggt ttaagcccta
     7141 cctgattcgc ctgataaaat tcagagcgag tgaccctctt tttgcgacat aggagagtaa
     7201 cttcaacatc ttcagagatt ggttgtagta gtttatcctt acctgtgact tccttagaga
     7261 tcagtgtgat ttcatgattc cacattcttg acctctttct ttgatgctat ctgtaaatta
     7321 tgcagtcgcc actgaaggtg acgtggcata tccaccccac cctcatagcg aaaggctgca
     7381 aaatcaacta caaacatttg gtcttctgag ctgtctaagt caagtagaac tcctaagtta
     7441 tcttctagtt ctgttttgac agcttcgatg attttctcca agggcttatc gcgtagtttt
     7501 gttgctatac ccaattttag cttaagcaat tctaataatt gaacattgtc cataactact
     7561 cctcgtctcc ctcttcaggt ttcccatcta ctacctttgt ttcttccttt tctacttctg
     7621 tagttaatgt gtcatctttc gacatatcct tatcttctac attcatcaaa aagatagatc
     7681 ctgcactatt tgccccattt agcagagtct ccgcaaactc tttatcaagt ttgtgcttaa
     7741 ctctagggta attatcccca accttatagc aatgtttctt tgggtctcgt aagtccttaa
     7801 aaggacggat taccttatat accatttact acctccttac aaaacagcat ctgtataggt
     7861 cacataaaat cctgcatctc cgtctacttt tactacatca aaacgattag cggttgccaa
     7921 atactgaccg tagattttgt catcttgcca tttgacagta gtctgcgcac ggtcaaacaa
     7981 tgtcgcaaat tctccaacgt caccgatgaa ggctttcaaa tctcccttgc tttctccaat
     8041 gatatcatct ggataaacaa caataacacg accagcaaac ttgtagccag ttggagatgt
     8101 gatatctgtt tggagcatgt agcgaccgtc cttgtccttg attttatcaa gagcagcgaa
     8161 catagattga gtacatacga tagttgcatt gtagtatgtt ttcaattcca cgttgagaat
     8221 atctttcaag ccgtccaaac cagctgcgct tttagatgta gctgtcttga gaactttagc
     8281 gatctcttta ttcttagtga tacgttcttg gttcttagtt tgtttagcaa ccaatcccat
     8341 gacatcgtag tcagcgtcat caataaattc ttgagatact ggcaaatgac cacgacgtgt
     8401 tttgatttca tagttcacct ttgtaaaggt tggtttagcc aattcagggt tttcttccaa
     8461 ctcttcaaca gtgttcattg cttgatcagt caattttaca actgaccatt taccgcttgc
     8521 gttcttgaca ttaacgatgt tgaccaatga agtcagatct gtcttgtctt gtttcgcttc
     8581 tttaggcgtc atcaattcaa caggaatgat tgcttcccct tcggcagatt tgaaaccatc
     8641 agcacgcgct tcttttgttc gtaagtaatg attaaatgct tcacgttgtc ccaatgtctt
     8701 tcctcctcgt tcttccattt tccccggagt tggtgcttta cgattttgct ctttgatttg
     8761 tttatctaac tcatcgatct cgttttcaag ctgtactttt tcagcttctt tttcttcaat
     8821 ttccctttga agaccgtcta cagtcttttc aactgctaaa acttcttcat catttttagc
     8881 acgatccaac ttttctaact caacaaccga acgtttgttc aattcttcga tagtttcttc
     8941 caactcaact accttagttg cttttgctcg catacgagca ccaaagatta atgccttatt
     9001 catagcttaa atttctcctt aatttctttc ttgcgcttgt ctagcgcttc acgattagca
     9061 cgcttctgac tttcgaagtc tttttgtcgt gcagcaattt ccgtttgtgg ataggctggg
     9121 aaagtacatg gactcacttc aaagatttct agctctaaga cagtgtccaa atacgaacca
     9181 tcttcacgtt cttccgtttc gatttttacc gggataaagc caaagctaca ccctataaca
     9241 tctccacgct tgacacgggc ataggcccca acagcttgag gatcatcctt gttaatgatg
     9301 atatctccaa aaagaccaac atcatcaaca cccagtgtca gagttccgtt acctgttcga
     9361 ccgagaacaa ggctatcatc atggttaaat aaagctctga tatcagcgtc tgtgacagct
     9421 ttctcaacac cagcacgctt gattacttca tgataaccac gccacaactc cgtctcttca
     9481 tcaaatttta taaaatagcc actcaacacc aagtctccag attcttcttc tctcgtttga
     9541 aattgagtgg cacgatagct atttcgcttt tgcattctct tcctcacctc ccttcagttt
     9601 attttgatct cctagtttct cctgagggag aaagttttca agaacaatca actcttccat
     9661 ctcaggatca ggagccatcc ctagccaatc cctccactca ttacgacgca ttgcagcact
     9721 gtttgccatt tgttgagcaa cagcagacaa ctccgtaatg ttgtaagaga agagtgaacg
     9781 aggatttagc ttgaagtaac gattgctaga caaaagtaag tccctggtta gtgtttgagt
     9841 aatagtggta gcaatactca tgacagtcgt atttacaaag ttgttatact ctgtcttgtt
     9901 gaactctcct acacccaaaa taaaagcagg tactcctaat agacctgcaa ctgttctttt
     9961 atccaattcc acagactcgt ttaaagcgat gtccgttaga ctaagcggtt ttacctgctg
    10021 aatgtccagc aatgcctctg gaacaatcca tggagcgcca accctgctag tactcaaata
    10081 cttctcagcg atacgctcac gcccttgctc cgaatctagt tcagcactag acgagtctac
    10141 tttaacgata agactaggaa tattcttccc gttcataaag ctttttttag tcttggtagc
    10201 catgttcaaa ctttgaacca catctgtcaa cgtcacccta aaaccagtac caatgtatag
    10261 aatatctgga tctggattga tgacgaagtg gactacttca tcaggggaat attcttcacc
    10321 cctaaatgag attacatagg aatccttatc tgtttggaat gaaacctctc tcatcggaaa
    10381 tggtcttaga ttagaaatat aatccgtaac aggttcatat tccacatgta ggacagagtt
    10441 cccatcgcca tataaaagca aatcgcgcac aatcttgaaa atccatgact tccttgtcat
    10501 gtgtttacac ggattgatat caatctttct agcaagccca tcacggattc tgatatcacc
    10561 tttatctgta ttctccatca agtggatggt catattagag accaaatcag caatcttatt
    10621 aaccgctgtc accacatctg gatttctggc caaaggtaca tacgagtcca tcaggtttga
    10681 caaccctaaa tctgaatgac tcagcatgtt gattgactta cttggcttgt ttcgtttcca
    10741 aaacttttca aaaataccca tgtttcctca cctcctttct aacgaaaagt attttgaaaa
    10801 agtgaatcaa agtgtttatt tcttacgata ttctgactga catcaattac ctgtttttcc
    10861 cattttactg tttcagccat caaatttttc atatgtcttt gacgaatagt tactacttcc
    10921 ccgtttaaaa ttactttaac tcgccctttg ttgatcagca agttaatttc atgttctgat
    10981 aatactattt cattcataat tcacctaatc aaagaatctc atcacatcac cacccttgcc
    11041 aagattagca agagcctgta tacaagcaaa gacgctggca tcaaacaagt caatccttgc
    11101 agtcccaccg tctccatcta atttctcata ttgcacagca tcgtccacct tttcaattgc
    11161 tctaacattg ctcacacagt attcgtaagc atcagaatga agatagtaaa attctttatt
    11221 cttaacttta aactcaatcc gtctgaatcc ctctgatttc agataaaaaa gctgaggttg
    11281 gtcaatcatc ttgaaccgag cttgtttcat cttcgtcaag aactcacggc caaacttcct
    11341 atccattccg acagcagcaa tcttgaaccc tttctccctc atcttgatga accatttgac
    11401 gatatcatca tagaggacgg tcggagtgtt gctcatcgtc aaccaaccgt cagactgcca
    11461 cccaaagagt ggaatcccgt catcattagc ttttttctga gcattaatcc gagggaagaa
    11521 agcatgtgtg atacagatat caacgtcttt ctcaccgtca tgatagacac catagagagc
    11581 agcagctgtt aagtcgtgca atcttgacaa gtccgcacca ccataccaac gaataggcaa
    11641 acgtgccagc tcttctaaac tccaatcgta gcaactatcc gacgcaataa actcatcagg
    11701 attaaaataa gcgttcatag agttagtgaa gatattcaag gtcttattga aaaactcatt
    11761 tcttgtctga ggatcattca tagcctgctc tgcttcttcc ttgagagcct tgagcgaaac
    11821 cgtgacaccc catgacggat tagccatctt gaggatattc tcgtccagat agttcaccac
    11881 gtccccatca gcagattgat tagccttaca gatgaagatg aaaaatgaat catcagtgac
    11941 taattgcttg agcacctttt gacagtattt cagacggtta gcaaggaacc cggtaggaat
    12001 atccccagct gtagagataa caaaaagcat actgttacgg tatgctgaca ttgttttttt
    12061 cataagacca tgtttcttac tgttcctcat tgtgtgagct tcgtccaaga tgataacatt
    12121 tccgttcaaa gagtccagac ggctctcatc attcgctaaa gcctggataa agaaagaacc
    12181 ttcatcacca aaattggcgg tgatagagtg ttcttggtta ttatccttga tacgaatgtt
    12241 cttatcgttc cagcgttcaa cgttgaatct taaaaaacca aaagcttcca tcgcttgctt
    12301 gactgagtta gcaacgatat agcatttgga accgctatct gtatctaata tctgataagc
    12361 aagtgcgatt gcagcagtaa acgaggtctt cccattcttc cgagcaagca tgatgagcgc
    12421 ttctttgaac ctgcgctcat tcgtaccctt gtagtaaaaa ccaaacagat taactacaac
    12481 gaaatgttgc cacggttgca aaagcaatgg cttgttacgg atagataccg caaacatatc
    12541 atcgccctgc tgatgaacta tcacgttctc gataaagtga ataacaaaat ccaccatatc
    12601 ctcatccatc tcaaaggttg gattttctaa atcacggaaa aaacgttcag cagcaaggat
    12661 gttttcttcg caatgttctt ctcggtgagt taagacgtgt tgagcgtatt ttttagcttt
    12721 atcaagatta cccattgcca gtcactcgct tcttcttgat ttcgttcttg aacttcagta
    12781 cctcagtaag aactgactca ccctcttgtt ctactacctc accgagcgac ttaggattca
    12841 tcatcaactg attagagtag ctgagtatat ctttcctcaa aatttccatc gctgtcaaga
    12901 ttggaacttt gcgctcattt tcagcaccag ccttattgac gtaggtgtct gttactggat
    12961 aacccatatc aacataatct tgagcaagtt tctgatactg gtataacata cctgcaaaaa
    13021 tgtcaatgat catttcgaac tctttacgat aagttcccaa gtctttcatc tgcttgacca
    13081 cttttgactt aatcgacttt gctgtaattg gtttagccaa aaactacctc ctttcgtcaa
    13141 aatcgcttag tttttacccc ctttttgttt gaaggccccc gacttggaaa aagttccctt
    13201 caccggtacc ctactggcca aaatgatttt tcaaaaagag gggggattaa aaattttcat
    13261 ttttcatttt tgaaaaaatt taaaaattct ttttttcttt ttttctgcca atacaatcct
    13321 tggttgatta ctctatcgtt cactctatca tgaaacgtat tatgtttctt attcgtcaat
    13381 ggcaagcaat tccattcaac aaattcaagc tcaggatatt cagacacagg aaagatatga
    13441 tgtaccattt ctgcttgaac agaaattccg taacgcaaac tttcttggca aagataatca
    13501 tgcttacgca ttatcctatc acggaacttc tcccacttct tagatttcaa ggatggtctg
    13561 ataggtttgt tatacatctc aaacctcctt tctcaatgct aaaagggaca ggcctttgac
    13621 ctatcccctc ctcatacaag aaatctatgc taccataata aacctttttt tgtgagactt
    13681 caagatgtct tttgtctcat tctgattctt taaaaaaatt attccatttt actagtatgg
    13741 ctgttaacgg tatatgcatt ccatttacaa atacggtatt cttttaccat ttttcacctc
    13801 ttgtaactat accaatttta tccctcactt tcacatatct tatattttgt taaactcact
    13861 ctgaatctca aacccttact aagcatgggt tttgaagagt ttcatttttt tagtttatgc
    13921 ttaactcatt atgtgaaagt aatatctaaa aaattaaatg acaaagttcc gtagtgcgtc
    13981 atcaagctct gcttgctcta tccctatgta tctcagggtg attgcaggtg atgagtgatt
    14041 gaacattttc tgtaatgttc ctacgtcctt tgtcttgttg taatatttat agccgaatgt
    14101 cttgcgcatt gtatgtgtgc caacattatc aatgccaagt tcttcagctg cttcatgtat
    14161 gatttgatag gctcgctcac gagtgatcgc tttattctga ccttgcctac tcttgaataa
    14221 gaaatgatga aatggtttgc cttcaacata tctcctcatt tctttcttga gttcttttgt
    14281 catccgtctt gttatctgct tgccagtctt ccgttctctc agtttgatgt gccaaccttg
    14341 aacatcttta actttcaagg taagtatatc tccgactcgt aagccagtat tcaggcctgt
    14401 gatgaatagc atataataca tctcattcca ttctctgaga taatctttca tagcttgaat
    14461 atcatcattg tcttttatcg gtgatacaaa ttccataact gcctcctttc tacaaaacaa
    14521 aaagccagct ggttgctgac tcatgatgtt cctctgttaa acaacttttc tgtaaaaata
    14581 ggatgactcc aacatgtgat ttgtgttttt gtttcagaag ttcatgctat cataatagac
    14641 ctttttttgt gagacttcaa gatgtctttt gtctcaatct tatttacaac tcacctttca
    14701 gtatagcgta ctgttctaag ataattcttc tacgtcgata gattgtagct ttgctcatga
    14761 atttctgttc tgctatttct tcccatctca gttgaggata tctccagcgc agattaaaga
    14821 tttccttatc ttcatcaact agattgatca aaagtttgtt aataatagct ttgaaccctt
    14881 cgagaaattt taaggttgga tcatctgcga ttctgactgc gatagtttcg gtaggtttgc
    14941 ttattcctac gctgggacca ctctgagcat ctgggtttcg agtttctaat tctagtcttc
    15001 tcaaatctat tgtacgttga atgttttgaa atttgaaaag ttctctgtct aatgttttga
    15061 ggtcttcgtc gctcaatttt ttcaatttcc acctccaagt ttttcaaaaa tgtaaacaag
    15121 ttatcaaaat tgtcgagatc ggatatctat tcctacttgt cttcgttcca taaaatctaa
    15181 ctgtttgttc agtaatacca aacatagtat tttaaaatat ctcactcgtt gacctccaaa
    15241 agctccggat tttcgtagac attgccgatg atttcctcat attccgtcca cgcatatcca
    15301 tctccaaatc cttttaggta tacagcaggc attccaccta tgtatgtgcc accgtattct
    15361 ttttctaaat atacttcatg gagacatcct cttgtacatt taacgatgtc accgatgaat
    15421 acctccttgc cgttcttgtc tctgagtcct gttgattgtc ctaatgttgc tggatttaca
    15481 ggacaccaag aacctatagt aatgtattgt tcattggctt ctaccacttc gttgataata
    15541 aatgctcttc ctctatcttc aattaaatgt ccgtattgcc attctccttt gcttttttcg
    15601 tcaatggata accctctaaa ttttggtatc atgctaacac tccttaaata aacaaactag
    15661 ctaaccatat caaaaatgca catgtaatga tttttgaaat actgctcttt accgcatacg
    15721 aataatcctc ttcagattct tttttgctag atagcacagg ccagatgaaa gatagtagtg
    15781 catccatccc taatgcttgc cagactgtaa ttttaccaac tggaacaatt gttgtgataa
    15841 tctcattcca tccatactga actacaaacg gcgatacaac gattacaaat accgccccaa
    15901 taatgattcc tagtcttttc attttataaa tcctcctctt tgacgaaagc accatcaatc
    15961 caacgaccct accgttttct aaatcacggt caataaacca ttgtttgact ttctctattg
    16021 tgttcatgat aactcctttg ctattgctgc tatgacatta actgtcacgc tatttcctgc
    16081 ttgtttatat aattgactgt tagagttgac ctcctgcgcc ttatcaaaag cccaatcagg
    16141 aaaaccttgt aacctccagc attctctagg tgttagcttt ctaatcctaa atccatctga
    16201 taaatgattg ttttcgtgat agctattgct agttaaagta ggagcgatgt tatgttctcc
    16261 gcctttatta taaccatgcc cacgttgaat aattttaggc tcaagtcctc caccttgata
    16321 ggctctgata gttggtgcga tgccgtctgt ttcgtaaacc accccacatt ggttaaaatt
    16381 gggttgcaat accccaaatt gttttatagt attgcttttt atagctatct tttgcccctc
    16441 tcccttgttt gttgttagcg tgggagctag accatcagct tgatagactt ccccattcat
    16501 tccgttgcca gatgggttta tattcccaat tttcatgact gattggttac tagttgactg
    16561 attttttccg ctgagaggaa aaattcttct ggtatgttct cttctaagat gtccgataat
    16621 gaacactcgt tcccgatttt gggggactcc gaaattcttg ctgttaagca cttgccattc
    16681 cacgttgtac cccagttcat ccaaggttga gataatggtc tcgaatgtaa ctccattttc
    16741 gtgattgagc aatcctttaa cattctcaag gaatagatat ttaggtctga gaatagatgc
    16801 gaacctagca atttcaaaga acaaagttcc tcgtgtatct tcaaaacctc gtctgtttcc
    16861 tgcaattgag aaagcttggc acggaaatcc tccacagata atgtccacac ttccgattcc
    16921 tcgaatagat tcatctgata ctgctgtgat gtcatgtaat tctatttctc ctttcgtatt
    16981 gtgtatcgct ttatagcttt ctctagcaaa cttatcaatt tcacaaaagc caatacattt
    17041 atggccggca gactccattc ctaaacgaaa accgccaatt cctgcgaata aatccaagaa
    17101 tttcacaaca tcacctcatc cccaactttc actttctcat acacgttctt caaaataact
    17161 atgaaattta cttaaattga caatagcgac ctcttcaaca gaatgctttc cgatgtcaaa
    17221 gtctggatca ttcttcccaa attctttttc tatagctttt tcagccagaa aaggcaaatc
    17281 gaatatactt gccccatttc ttaaagcgag cgcttgaccg tatttgttca ctattcgata
    17341 ccctatatca aacggtctga tttcccttgg gacttttatg catttacttt gattcttcat
    17401 tccttcttca agtgtttgtg tcatcactcc acctcctcaa tctcaaaccc ttcacaatca
    17461 aacacccagc cgatttttgc attttctagt tctttacggg tgtgggaata tatagcatcg
    17521 tctaaactaa agctttttgt aaagaagtac ctttccaaaa gttctccata aaccaacata
    17581 ttttctttaa tattcccttt aatctttacc agataccgct tctctttttc gacctcatag
    17641 ccgtcaagcc atgcgcgagc gaagaggtct tggttgctcg cctttttaat ccataatata
    17701 agatcgaaac tttggttgtt ttctttcata aagtttggag tcatagcagt atatagacta
    17761 gttgttaaat gttctttaca aacctcaatc caatccgcca caaactgcgg aattttgact
    17821 ttttggggtt cgtctagttg tttcaactct ttcaaaaaaa gttcaaccat tgaagtataa
    17881 ggtacaggtt cataaaaagg gctgtgttca ttccacaatt cttcatactt cttaatcaat
    17941 gccttaatat tcatcttagt ttcctccata aatcaaataa actgcaataa ctacctgagc
    18001 catgcttggc gaatagccaa cccaatcatc aaactcctta gattttggca accaaccctt
    18061 agtagctccc aaatcatagt ctgtaggctt ttcatcagcg aagatacatt ccatcgctcc
    18121 cataaacgtc ataccatctt ctgccatttc ccaaaaatag tccgcccggt ctttcaccgc
    18181 ttgtggtaaa tcttgcttgg gaggttgcgg cttcccgtct tctaccgtcc agttgtatac
    18241 ttcattaact tttcgcttta actcttccat catcttccaa ctcctccact ttccgtctca
    18301 attctttatt ctttttcctc aacaaatcgc gctctagcgc tctaatacgt ctcttgcgtg
    18361 catcgcacgg tttcgaatac tcgattatct tctcttcgtt ttgatcgatc gtgcgtttca
    18421 gtccgtcaat ctcagcctgt ttatcgtact tcatcttcta aaaacctttc aatagcttct
    18481 ctgtaggaga cttccaccag accgtctaag tcgttcaggg cttcaatata gtctggacga
    18541 ccttgcccgt actgctcttt caaaaattca acaaagagat gaatttcctg ataggttact
    18601 ccaaccatgt ttcttacctc ccactaaatc agaaattccc atacatttgt gaaaattctc
    18661 aaatgctaaa tccattaaaa tatttttagc cattatttcc ctcctgaaaa agtcgctaaa
    18721 tagtaacaat ccttagaacc gtagtcaaat cgtgtcgtcc gctgaccaat gtgcttctga
    18781 aatcttggat gagtgatagc cgagaaagcc cactgatgat cttccatctg ctcaatgaga
    18841 tcatcgacat tgtcaaacct cccaaggtaa aacttgcagt gcccgttata gacgaagtaa
    18901 agctctaaca tcaatacctc ctaaaataac ttcaactgct tctcataagc atcaagtctc
    18961 tgttgagcga ggttgaaaat acttttatca atctcgcatc caacatagtc aaatcctagc
    19021 tctccgcaag caatcaagct acttgctgaa ccgacgtgag tatcaagtat tttatcgcct
    19081 tcttttgcgt aagtttgcaa taaccaaagg taaaggttga ctggtttttg tgtcggatgg
    19141 attctaacct cattcaatgc cttatttcct tgttgtatat gaccttcaga gattgattta
    19201 ccttgcatca taccattcca catgtaacga aatagcctag tactatcatg ataactgcag
    19261 tacgctatct cacaatctga aaaacttgat tgaccattaa ctttgtccca cacaatacgg
    19321 ccagaaccaa aagaatagtc gaagtagttc acaccccaaa taatttgatt tttagatacc
    19381 ctgaaaagtt catcaaaata atctctgttt ggaattttcc actctgagat ttcgccatag
    19441 agtctgctta cacctattgg actgattttc cgtccgtaaa atttcctttt ttctggacca
    19501 gaaaaatatg gtggatcaac aatagctagg tcaaagtaat tatcaggata ttgtttcatg
    19561 atgtccatgc agtcaccatt taagaatttc atcatcactc cacctcaaca gggtaaaagt
    19621 tcccaaagga acccctcaaa gcctttccaa cctgtacggc agccgcccga gaaataaacc
    19681 gcatggcttt cttctcctcg gaacacgaaa tatccaagcc agtcacactg ataattgcag
    19741 accttagaaa cggcttatcc tctcttgtcc catgctttaa aataaacatc agccacccct
    19801 attctaaaaa tattgctttc gcttgtttgt caaatcattg aaaaccatca aatggtcttt
    19861 atctacaccc ttcattagtc tggacatgaa aggtctgcca tatctttttt gaatatcggc
    19921 agaaatcaaa tttgtggtaa tgattgtgtt tgaacgctta ttcaagatat tgtagagaat
    19981 agtaaatgac cattcgctat ctttttccat tcctaaatca tccaaaacca agaacttagc
    20041 actagcaatt ttattgacca gaaactcttc ctgactaaaa tcagctttaa tcttcatcag
    20101 caagtcagtt acgttaataa aaatagcaat ctctttcgtg tactcagata gagccttaac
    20161 catagcaaaa gccaaatggc tcttacctgt tccagcttct ccttgtaaca cgatgttgtt
    20221 cctagcaccc tcagaccact cacgacaaat cctctttgca aaagctagct tttccgcttc
    20281 tttttcggtt ggtgtttcaa aattgtccaa agtagcattt ttcaaaactt catcataaag
    20341 agagaacttt tcaagatagt atttcctctc tcgctcattc tcagcattag ccagttcatt
    20401 cactctttcc tgattttctt catgaatccg ctcagattca cacatgcgac atacaacact
    20461 ctcggtcctc aatatcttta tcaaagggat gttatgcttt tcgcagaact cttcttgttg
    20521 ttctgtattc ctacgataag ataaggcgat ttcctcaaac acattgtcta ccatactagc
    20581 cgacctccgc attcatgcca gctagccatt tcagacaagc aggcaaccac ttgatgaatt
    20641 ggttggtctg ctaaaagagt tttcttctcg tagcttaacg gataatagtc aatctcgaat
    20701 tgttcaatta gttctagtac ccccattcgt ccttggcctc ctgttcttct ttcttatcct
    20761 tgttcttctt ttccgattga cgaacctgtt caacagtggt aacattgttc atctgccaat
    20821 ttcttaaaat cccaccaata tatttgatgt tcggctttcc tgagttaata gcagtcttca
    20881 atgcttcttt caccaaatcc acatcattct catttagtag atggttgatt tcttcaattt
    20941 caaatccaga taagagtcta cgaaactcag attgaaaaag ttctaagata ttttcttcac
    21001 taccactact agtagtagtt attcttttct tattcttatc tttatctaat ctattcttat
    21061 tcttatcttt atcttcttct agtgcgttac cgtccgttac tgtaacgtta cctgtaacgt
    21121 taccaagagc aagatttttt tgttttttac ggtatttggc tacacggtta cgtgtctgtt
    21181 ccttgatttt ctccattccg tcaacgtttt gatgtttttc ccaatttggc aagctaataa
    21241 taccatcgat aatctcaatc atcccaaact gttcaaaaac tccaatagcc attcttactg
    21301 tattcaatgg tctacgaaaa atagtagcta acatttcatc tgtatagtga accttatcag
    21361 tcatcatcaa caaaccatta ctgttatgtt ttccagcaag tgtcaaaatc ttgaaccata
    21421 tcactaagat ggcatcagga tcaggcaagg catcaatcag gcaaatcttt tcatcgtcaa
    21481 aaatatcggt tgtgattttt atccacttaa tttcagacat accgagcacc ccacttcctg
    21541 cgattggcac gatacttcat acgcatatcc tcatagatgt gcctgccttc cagctccatt
    21601 ttttcaatct ttagcagctt atttttaagg gtcacataac gatagtcctt tgctagtttt
    21661 tcatagtcgg ttaggtattc tttgactagt aatagatttt tataatcgtt ttcccatatc
    21721 gtaataaaat gtcttgaagt tgattccctt ccttccagtt ctttaacaat cataatcagg
    21781 ttatccagcg attcaatcaa ttcttccatt tcctgccctc ctcattacag aagtctgatt
    21841 gcagactgtt taggttctgg caaagctaat ggctcaggac gcaatccttg aggcggttcg
    21901 ttgtcgtagg taaagccctt gaacggacga cgaatattct tgcggatttc ttgacgttca
    21961 gcttctctac cacgttcgta agcatggtta tagccttgaa taatcataga cgcaaattct
    22021 tgctcttctc gtctttcttc ttccttgcgt tgttcctgca atttgatatg acggcaagcc
    22081 cctgcaaatc caagcagtaa ggctccaacc cccatcaact ggtctaaaat cggtggttca
    22141 aacattttta tctccttatc ctctttttgt gctataatat agtcaaataa ttttgctaag
    22201 accttgtcca gaagcctttt agtaaagtta ttatatttga ttagagagcc attctttgat
    22261 ggctcttttt gaccatttct taccaggtaa ttcctttgga aatcccttta agtaacgata
    22321 attatctgaa aaggtggcat acttaattcc tagaaattcg caggtagtgt tcacatccat
    22381 caactctgga tagtgatcac tatctttttc tatttcgact agccttgtga ttgtgtcctt
    22441 gataatagat ttaatccatt cagacagtga aagtagaaca ttgtccatct tcttcccctt
    22501 tctagacgtc atcaaatgag ttcaatttca tgattttcat cttggtatta gtgcttggct
    22561 cccacgtcat ccagtaagca agagcggcat ccgcatgctt cttgggtagc aagtcatagc
    22621 gactaatgtt gaagtggtct ttgaaatcaa tctcagcttg tctaaagact gattgagcaa
    22681 aaaccttatc cgcataagca ggactgtcaa taccgccaag gcaagccacg acccgagctt
    22741 tgcgcttctt cagtaacgac tgagcatagc ttggatgaat cggttgctca ctctttagat
    22801 agtcgatatc ttccagcatg gtagcctgtt gctcacgcaa tttcttttga ccagtgaata
    22861 gagcgataaa ggcatcctcg tccaagtcct cgcggataaa tccgccctgc ttgcgaatag
    22921 ctggcaagac ctctgaagtc acccagcgct tgaattcctt agcttgaggc aacttgctgg
    22981 ataagatgag agagtagaga ccagattcgt tgatgatcaa catatcctgt gttccgccac
    23041 tagtagggat gccctgtttt agggcgtcct cttcatcaac gtgaagagta atcgcatttc
    23101 tagccttgct atatcctagg atgtccgcta catccttccc gacaaaccac ggctcgtcat
    23161 caattgtcaa agtacggact tcttgtccgt gaaaattaaa aatttcgttc atagtattcc
    23221 tttctaaatt tggtataatg aaaataaaac gattggagaa atcttatgga ttatcaaatt
    23281 cttattcaac ctgcaattag tgtcattctt gcaataatct caggtttatg gtcatatatt
    23341 gcatcaaaag ctaacaataa agctgagatt gaaaaacagg ccaaagaaca ttcacatatc
    23401 gtagagaaac ttgaaaaaga atttcattat cagatagata ctctcaaaca acaacacacc
    23461 ttggaacttg aaaaagtcaa acaagctcat gaattacggt tacaagaact tgaaaaggta
    23521 tctcagattg atactgaaac cgacaaggct atgaagatga atgatcttat ctacaaaact
    23581 tttacaggcg aagttgattt ggacaaagct ttaaaattag ctgataaagc taacaatcac
    23641 aaacaaaaac taaataaaaa atttattcaa aagacttcta aaaaatcata aattaaattt
    23701 atttctaatt ctttcaagct catcatcttg tattttttta tactcgttga tgcgcttttt
    23761 tctgtctctt ttgctagcgt agtatgtagc aaaaccaatg ataagattga ttatgacaac
    23821 aaagtaaaac catactagtt cattcatctc caccctccta ctccagcacc ttactgccga
    23881 ctaccaatcg tttaacgaca acgtccatct ccttaaattc ggcattctct gcacagtagc
    23941 ggacgctctc actgatgatg tgacaaatag ataccccgta ctcgttcgcc aactccgtag
    24001 caatctccca ggcatctttg tcaatccgtg ttactttttg cgctgcgttg ttcatactat
    24061 ttcctcatgc tctaactatt ttcccaaggg ttttcaatac ccaaaatatc tacgactttt
    24121 tctttcacat aatcacttcc ttttccatac ttcagcagtt ctgaaataac tgatgatgtt
    24181 acagatactt gttttgccaa ttcggcttga gtcatatcca gctcaatcaa acgagttttg
    24241 attttagcct tgattatctt tagttcttta ctcatatttt tcctttctaa atttgatata
    24301 attaaaataa aaacgattgg aggagaataa tgaaatcttc attttttcac tatctaaagg
    24361 aaatcatctt atatggtgtc ctagttccga ttttgacagt tatcgtagga tttcaccttt
    24421 ttactacctt ctatcctatt tctgattcac tgttaacaga tttcttgaaa gcttttacag
    24481 aacaaagaat ccttgctatt gtattcgttc ttattctttg ctttatattt ttcggttcaa
    24541 tttattactg tatttcatgt ggacgaaata gaaaattgat acctgataaa gtttatacac
    24601 aaatcacaac ttacatttca tctgtaggtt tagggactgc agtgatagct gtcgctacct
    24661 tgactctcac agaattacag ttttcaatcc ttacaggttg gattgctttt atcgctttgt
    24721 tgttgccact tctgaagttt aaagtccaat acagcaccta tcaaagtagc gacaatgtag
    24781 cacagaaaac taccgaaaac aaagccaatt aagaaaggct ctaccattct cctctccccc
    24841 tttcttttaa aaaattatct aaaaagttag cgaacttctt gacaactcta gtcaaatgtt
    24901 ttaaaataaa aacatagaga aaagacctac taaaagtaag ttttacctac agtaaacgga
    24961 cgccaatcag ttttgtaagg ctttattttt tagttgtcta gttcgctaac tctttagctt
    25021 acgaatatta ttttaaaaca tttgactaaa taagtcaact attttctaca aatattttaa
    25081 aattattttt cgtttgctta gaaaggttga aaaattaatg tttgtagcat tcgataaaat
    25141 aaaagaatta gctgataaac aggggatttc tataaatatt ttagaagaaa aacttggtta
    25201 tggaactaat actttatatc gattaaaaag aagtaatcct agttcaaaag ttttaaaaga
    25261 aatagctgat tattttaatg taagtgctga ctacctactc ggacggacag ataatcctgc
    25321 tatcgctgga agtgatgaat ttgctcaagt aaatggacaa atcatagact tacgcaaagc
    25381 agcagccaac accatgttat ttgacggaaa accactaaat gaagatgata tcgacttcat
    25441 cacatccgtt ctatccgccc acttcaaaag caaaggagaa cgctaatgac tatcacgatc
    25501 aatttcacag aaaaaaactc ctacatcacg gactacctaa ccaaacacgg tatcgacaca
    25561 acaaccatgg attttgacga cttcatggta ctcatggaag atatcgaaga cgcacgagca
    25621 gccgaccaag cctatatgga gtatttagcc gacccagcta cttataccat ggatgaggtc
    25681 ttggatgaac taggactatc tcgagaggat attgcttaat gtatcggcta gatattgata
    25741 aaaaagctct caagcaactt aaaaaactag ataccccaac cagaaaacaa atcctatcct
    25801 ggcttgctaa aaacattgaa aacacgacca atccacgaca acacggaaaa gcactaaaag
    25861 ccaaccttgc aggttactgg cgatacagag tagagaatta ccgcatcatc tgtgatatcc
    25921 aagacgataa actagtcgtc ctagccgtgg aaatcgccca ccgcagagat gtttataaat
    25981 aacgaaggag aactatgaca ctcgctaaac tctgcgaaga atatcaagta gagctttgtc
    26041 tcttcgacgg ttcaaactgg cacagtagcg gtttctacaa tccagacaca aacgtactcg
    26101 ctattgacca caacttagct cctgaacaac aaatccaagt cgccctacac gaactcggac
    26161 acaaagacca tacacgctca gagtaccaaa acgctcgcct acgctgtgaa aacgaagctg
    26221 ataggaatat gatccatcat ctcgtgaaag atgcactaga aagcttagac gaccccacag
    26281 agtttgatta cctcaaattc atgtcttact acaatctaaa aactatgact aatgaagtca
    26341 tggtcaagga agagtacttg gcattagtaa attaaaaatt gcattgaaga tatttatata
    26401 gaggggaaat atatgcaaaa gactgttgaa aaaatattat tcagagtcgc tggagtgaca
    26461 aaatataaaa aagcagtaaa agaagcttgc aatatgattg ctgaagataa cggaatccca
    26521 gaatatgcaa agtactatag caatttatca actaaggaac ttagagaaga acttgaagaa
    26581 tatggtctga aagttttcaa atatcaagat ttagactttt tcaatattga gctcgttcca
    26641 gaagtagata atagatatga tcctaatgct ataaaagttt tgatatttga taatcatgta
    26701 ggatatgttc ctgcaaccat tgctaaaaca atacgaaaat attttgataa taaaaaatat
    26761 aactttgtaa tagagggaga gataaaaggt ggcccatata aagaatggga cgagtatgaa
    26821 gaaaaagttg tcacaaataa tgatttggat gttggttttg aaatttacct taccattgtt
    26881 gattcttcac aaaaagaagt aattcagagc gaatcatctg agataattga tgataacatt
    26941 tccaataaag aagttacgga aactgaagct attgaaacta aaacaactga aactgaacat
    27001 attgaacaaa atattgttag tgacagtgtc gctgatatag taaacgagat taatctttca
    27061 gaaacatctc ctaagaaaaa acttcctgcc aataaaatca tattttcagc actgtatctt
    27121 ttcttagtct tttttggagt tgttggtatt ccaatcgctc cattccttgc agtccctttg
    27181 acagcttgga gtttgtataa actatacaaa ctattcagaa aataaaaaaa agccccacaa
    27241 tcgccctcgc caaagtttga ttgtgaagct tacccttata aaaaatcagc cattaaaaag
    27301 gcctcttttc tataccctat tttacaccat gaaaggggtg atgtcaatat tctcaatgtt
    27361 tagaccttgt ccagaagccg ataaacaagg agaatacaat gaaatataat aaaacaaaat
    27421 acccaaatat ctattactat gagactgcta aaggcaagcg ttactatgtc agacgttctt
    27481 ttttcttccg aggtaaaaaa agagaaaaaa gtaaaagtgg tttcacaact ctccctcaag
    27541 ctcgtgcagc cttggtagag cttgagcaac aaatccaaga acaagaatta ggtatcaata
    27601 cgaatctaac gcttgatcaa tattgggata tctattccga aaagagattg tcaacagggc
    27661 gctggaatga cacttcctac tacctcaatg acaatctcta taagaaccat atcaaggcaa
    27721 agtttggttc tatcctgctt aaaaatttgg atagaaatga gtatgaacta tttatcgctg
    27781 aaaagttgca gaaccatacc agatacactg ttcaaaccct caattccagc ttcatggcat
    27841 tgctgaatga tgccgtgaaa aatggtaatc tgctctcaaa tcgcttgaaa ggtgttttca
    27901 tcggccagag tgatatccct gctgcaaaca agaaagtgac tctcaaagag ttcaagactt
    27961 ggatagcaaa ggcagaagag attatgccaa aacaattcta cgctctgacc tatctgacaa
    28021 tttttggatt gagaagagga gaagtctttg gattgcgtcc aatggacatc actcagaacg
    28081 acagcggacg ggctatactg catcttagag acagtcgaag caaccagacc ttaaaaggga
    28141 aaggagggct taaaacgaag gattcagagc gatatgtctg ccttgatgat atcggaacag
    28201 acctgatcta ttatctgata gctgaagctt ctaagattaa gcgaaagtta ggaattatca
    28261 aggaacagca caaggattat ataactatca acgagaaagg tggtctcatc aatccaaatc
    28321 agctaaatag aaacttcaat ctagtgaatg aagcaacagg attgcatgta acacctcaca
    28381 tgatgcgcca cttcttcacg actcaaagca ttattgcagg ggttccgctt gaacaattaa
    28441 gccaggcgct ggggcataca aaggtttata tgacggatcg ttacaatcaa gtagaggacg
    28501 aacttgctga agcgacaaca gacctatttc ttagtcatat tcgctaaaaa agtccccgcc
    28561 aattccccga ccaaaatccg aaaaataccg aaaaatatcg aaaaattatt tttagaatag
    28621 tccccaaaag cctgaaatag agctaaaaaa ctccacctga ttcggtggag ttaagggaga
    28681 ttattatgaa aaagaaaagt ttaggatatt tgttacaaca agttaggagg tcttcttgta
    28741 actgtctata gtatacccga cctatcttaa acaaatctta aaaatctctt aggaccaaac
    28801 actttctaaa atatttgttt gttcacgacc aggacctact gagaaagtag aaatacgaac
    28861 gccaaccaat tcactcacac gacgaacata gttacgcgca ttctcaggaa gatcttccaa
    28921 attgcgaact ccggtaatat cttctgacca acctggcaac tcttcataga taggcttgca
    28981 acgtttcaat tgctcaagac tagctggata gtagtcaata cgttgaccgt caagatcata
    29041 ggccacacag attttcacag tatccaaacc gctcaaaaca tcaatagagt tcaaagaaag
    29101 gttagtaata ccagaaacac gacggctatg acgcatcaca actgagtcaa accaacctac
    29161 acgacgtgga cgaccagttg ttgtaccata ctcatgaccc acttcacgga tacgttctcc
    29221 cacttcatca aacaactcag ttgggaaagg accatctcct acacgactcg tataagcttt
    29281 acatacacct acaaccttgt caatcttgct tggaccgaca ccagaaccaa ttgtcacacc
    29341 accagctaca gggtttgatg acgtaacaaa tggataagta ccttggtcga tatctagcat
    29401 aacaccttgt gcaccttcaa aaagcacacg tttgccatta tcaagcgcat cattcaagat
    29461 aacagatgta tctatcacgt atttcttgat ttgttgacca tattcgtaat attcttcaaa
    29521 aatatcatcg aaaacaatcg ctttactgtc atacaatttt tcaaaaagac gattcttttc
    29581 agcaaggtta cgttctaaac gctcacggaa aatatcttta tctaaaagat ctgcaatacg
    29641 aattccaaca cgagcagcct tgtccatata agctggacca attcccttaa ttgtcgtacc
    29701 aatcttattg tcgcccttag cttcttcttg caagcgatcc aactcgatat gataaggcaa
    29761 aataacatgc gcacgatcag aaatacgcaa gttatcagtt gttacacctt cctcatgaag
    29821 atagctcaac tcttttacaa gagatttagg atttacaacc ataccattcc caatgacaga
    29881 tattttttca gggaagaaaa tcccagatgg aatcaagtgc aacttaaatt tcttaccgtc
    29941 aatcacaatc gtgtgaccag cattatcacc accttggtaa cgtgcaatca cttctgcatt
    30001 cgctgaaagg aagtctgtaa tcttcccttt accttcatca ccccattggg tacctacaac
    30061 aacaactgaa gtcataatct tgtctgagcc ctcaggctct tcctttctca catacatggc
    30121 aggactctca cctgcaatta tatcttacaa tttattataa taaaaaatcg cctttttatc
    30181 aagaagaaac aatagaaaga tttgctattt ccaactatta aaaaatgatt tag
//
LOCUS       DAVLUM010000025        29936 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLUM010000025 DAVLUM010000000
VERSION     DAVLUM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.025"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(1..753)
                     /locus_tag="VYN42_000932"
                     /pseudo
     CDS             complement(1..753)
                     /locus_tag="VYN42_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567576.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(891..2513)
                     /gene="groL"
                     /locus_tag="VYN42_000933"
     CDS             complement(891..2513)
                     /gene="groL"
                     /locus_tag="VYN42_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1462030.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2529..2813)
                     /gene="groES"
                     /locus_tag="VYN42_000934"
     CDS             complement(2529..2813)
                     /gene="groES"
                     /locus_tag="VYN42_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1462031.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3083..3478)
                     /locus_tag="VYN42_000935"
     CDS             complement(3083..3478)
                     /locus_tag="VYN42_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1462032.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVIEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3555..4316)
                     /locus_tag="VYN42_000936"
     CDS             complement(3555..4316)
                     /locus_tag="VYN42_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1462033.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTHCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(4349..4975)
                     /locus_tag="VYN42_000937"
     CDS             complement(4349..4975)
                     /locus_tag="VYN42_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1462034.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVACLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4991..5308)
                     /locus_tag="VYN42_000938"
     CDS             complement(4991..5308)
                     /locus_tag="VYN42_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1462035.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(5305..5604)
                     /locus_tag="VYN42_000939"
     CDS             complement(5305..5604)
                     /locus_tag="VYN42_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1462036.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            5692..5772
                     /locus_tag="VYN42_000940"
                     /pseudo
     CDS             5692..5772
                     /locus_tag="VYN42_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(5901..6092)
                     /locus_tag="VYN42_000941"
     CDS             complement(5901..6092)
                     /locus_tag="VYN42_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1462037.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6253..6927)
                     /locus_tag="VYN42_000942"
     CDS             complement(6253..6927)
                     /locus_tag="VYN42_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462038.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6933..7379)
                     /locus_tag="VYN42_000943"
     CDS             complement(6933..7379)
                     /locus_tag="VYN42_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462039.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7493..7996)
                     /locus_tag="VYN42_000944"
     CDS             complement(7493..7996)
                     /locus_tag="VYN42_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1462040.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7993..8355)
                     /locus_tag="VYN42_000945"
     CDS             complement(7993..8355)
                     /locus_tag="VYN42_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1462041.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8421..10286)
                     /locus_tag="VYN42_000946"
                     /pseudo
     CDS             complement(8421..10286)
                     /locus_tag="VYN42_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(10318..10767)
                     /locus_tag="VYN42_000947"
     CDS             complement(10318..10767)
                     /locus_tag="VYN42_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1462042.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(10891..11607)
                     /locus_tag="VYN42_000948"
     CDS             complement(10891..11607)
                     /locus_tag="VYN42_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1462043.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12488..13903)
                     /gene="ply"
                     /locus_tag="VYN42_000949"
     CDS             complement(12488..13903)
                     /gene="ply"
                     /locus_tag="VYN42_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1462044.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13914..14246)
                     /locus_tag="VYN42_000950"
     CDS             complement(13914..14246)
                     /locus_tag="VYN42_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462045.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(14317..14925)
                     /locus_tag="VYN42_000951"
     CDS             complement(14317..14925)
                     /locus_tag="VYN42_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462046.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14938..15396)
                     /locus_tag="VYN42_000952"
     CDS             complement(14938..15396)
                     /locus_tag="VYN42_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1462047.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15521..15920
                     /locus_tag="VYN42_000953"
                     /pseudo
     CDS             15521..15920
                     /locus_tag="VYN42_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16685..16945)
                     /locus_tag="VYN42_000954"
     CDS             complement(16685..16945)
                     /locus_tag="VYN42_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462048.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(17004..17555)
                     /locus_tag="VYN42_000955"
                     /pseudo
     CDS             complement(17004..17555)
                     /locus_tag="VYN42_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17545..17742)
                     /locus_tag="VYN42_000956"
     CDS             complement(17545..17742)
                     /locus_tag="VYN42_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462049.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(17746..18330)
                     /locus_tag="VYN42_000957"
     CDS             complement(17746..18330)
                     /locus_tag="VYN42_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462050.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(18738..19163)
                     /locus_tag="VYN42_000958"
     CDS             complement(18738..19163)
                     /locus_tag="VYN42_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462051.1"
                     /translation="MTSRVFIDADCISVFLWVSAEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILVEAFKA"
     gene            complement(19292..19651)
                     /locus_tag="VYN42_000959"
     CDS             complement(19292..19651)
                     /locus_tag="VYN42_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462052.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKKMILV"
     gene            complement(19697..19903)
                     /locus_tag="VYN42_000960"
     CDS             complement(19697..19903)
                     /locus_tag="VYN42_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462053.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(19890..20051)
                     /locus_tag="VYN42_000961"
     CDS             complement(19890..20051)
                     /locus_tag="VYN42_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462054.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(20397..21353)
                     /gene="lytA"
                     /locus_tag="VYN42_000962"
     CDS             complement(20397..21353)
                     /gene="lytA"
                     /locus_tag="VYN42_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1462055.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21729..23099)
                     /locus_tag="VYN42_000963"
     CDS             complement(21729..23099)
                     /locus_tag="VYN42_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1462056.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(23406..24572)
                     /gene="recA"
                     /locus_tag="VYN42_000964"
     CDS             complement(23406..24572)
                     /gene="recA"
                     /locus_tag="VYN42_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1462057.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(24627..25883)
                     /locus_tag="VYN42_000965"
     CDS             complement(24627..25883)
                     /locus_tag="VYN42_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1462058.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(25968..26984)
                     /locus_tag="VYN42_000966"
     CDS             complement(25968..26984)
                     /locus_tag="VYN42_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1462059.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26992..27510)
                     /locus_tag="VYN42_000967"
     CDS             complement(26992..27510)
                     /locus_tag="VYN42_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462060.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            complement(27500..27943)
                     /gene="tsaE"
                     /locus_tag="VYN42_000968"
     CDS             complement(27500..27943)
                     /gene="tsaE"
                     /locus_tag="VYN42_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1462061.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(28030..28650)
                     /locus_tag="VYN42_000969"
     CDS             complement(28030..28650)
                     /locus_tag="VYN42_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462062.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(29033..29896)
                     /locus_tag="VYN42_000970"
     CDS             complement(29033..29896)
                     /locus_tag="VYN42_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462063.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
BASE COUNT         8945 a         6679 c         5158 g         9154 t
ORIGIN      
        1 atctactata aatttgatat gagaatagtc tttctcaaca tccttaccca acaagaatgc
       61 tgtagcgtcc ttcttaactt gaaccaggtc aatattctgg gcttgggctg catagacgca
      121 gccacaataa cattgacgat agatatcata ctcctcacac atctctactg aacgtttgta
      181 gccttgattt ttcttgaaat cgttgggaag atagtgggtc gtgtaaattt tttgcacatc
      241 gattccgatg ctgttgatgg tttgagaatt cttatgagga ctgatggtca aggctgaacc
      301 aaagtagtca aagcccaagt ccatagccac ttgcgctgtt ttatccagtc ggtagtcaaa
      361 acaaaccttg caacggtcgc caccttcggg ctcctcctct agtcccctaa ctagttttcg
      421 gtattaattg ggttcgtagg gagcttctag gtactgaacc gtatttcctg tccgctcatt
      481 aaaatcacta acaaatttct tggtgacata gacccgctta tggtattcta ccttgggatg
      541 gatattagaa ttggcaaaat agatggtcac atctgcatac ttggtcaaat attctagtgt
      601 ataggtacta caaggggcac agcaaacatg cacgagaatg gttggccgtt gctcattttt
      661 ctaccatact tctaccattt tctgcatgac acggtcataa ttaatcttct gattgggggg
      721 catcttgcac agaatttctt ctacatcgat catgttcttc tcctttttct agtcttattt
      781 tatcatataa gttaggagag ctcaaatcaa tttagaagtg aatattataa aaagaagggt
      841 tagtcattcc ctccttttgt gttttttata agttgttttc tatagaatgc ttacatcatc
      901 ccgcccatca tgcttggatc cattgctgga gctggggcta ctggttctgg tttattggct
      961 acgactgctt ctgttgtcaa aatcaagctg gctacagatg ctgcattttg tagggctgaa
     1021 cgactcactt taactggatc aatgatacct tgatcaatca tgttaaccca ctcgccagtt
     1081 gctgcgttaa atcctatacc aagctcagca tttttcaaac gatcgataac gatagatcct
     1141 tcaaatcctg cattgtgagc aatttgacga acgggttctt ccaaagcacg gagaacaata
     1201 ttacgtcctg ttgcttcatc tcctgtcaat tccaaggtag caacagctgg aatcacattg
     1261 gcaagagctg ttccaccacc tgcaacaata ccttcttcaa cagctgcacg agtagcgttg
     1321 agggcatctt caatgcggag tttcatttct ttcaactcag tttcagttgc ggctccgacc
     1381 ttaataaccg ctacaccacc tgacaatttg gccaagcgtt cttgcaattt ttcacggtca
     1441 aattcagaag ttgtagtttc gatttgagac ttgataaccg caacacggtg agaaatcgct
     1501 tcaggatttc ctgcaccttc tacaataacc gtgctatctt tgtccacggt cactctcgct
     1561 gcttgaccaa gagcttcaat tgtcgcatct ttcaactcaa gaccaaggtc ttctgtgata
     1621 actgttccgc ctgttaagat ggcgatatct tcaagcatgg ctttgcgacg gtcaccaaaa
     1681 ccaggtgcct tgactgctac tacgttgaag gttccacgaa tcttgttcaa aacaagagtt
     1741 ggaagagcct caccatccac atcatccgca ataatcaaga gtggacgatt gctttggaga
     1801 atgctttcca aaagtggcaa gatttcttgg atattggaaa ttttcttgtc tgtaatcaaa
     1861 atgtacggat tttcaaggtc agccaccatt ttttcgctat ctgtcaccat gtactgtgaa
     1921 aggtaaccac ggtcaaactg cattccttct acgacttcaa gctctgtttc cataccacgt
     1981 gactcttcga tggtgatgac accgtctttg ccaacttttt ccattgcttc agagatgtac
     2041 tcaccaactt tttcagaacg agaagatacg gctgcaactt gagcgatagc ttctttattg
     2101 gcaacaggga tggcgttgtt tttcaaagct tcaactgctg cggcaactgc tgtttcaatc
     2161 ccacgacgaa taccgattgg atttgcacct gctgtgacgt ttttgattcc ttcacggacg
     2221 atagcttggg tcaagactgt tgcagtcgta gttccgtcac ctgcgatatc attggtttta
     2281 gaagctactt ctgatactaa cttagcaccc atattttcaa aatggtcttc caattcgatt
     2341 tctttggcaa tggtcacacc gtcattggta atcaagggtg aaccgaatga cttttcaaga
     2401 acgacattgc gaccttttgg tcccaaggtt actttaacag tgtctgcaag gatatcgaca
     2461 ccacgaacca tggctgaacg ggcatctgat gaaaatttaa tttcttttga catacttact
     2521 ttctccttct attcctcaat gattgccaaa atgttagctt cgcctacgat aatgtacttt
     2581 tcatcgccat ctttgacatc aagacctgcg tgggcttcaa ctaagacacg atctccagtt
     2641 ttaacacttg gagcaaccaa gtcaccgttc aaggtacgaa caccttgtcc agtagccaca
     2701 acttgagctg ttttggtttt ttcttgggct gagcctgcaa ggacaaagcc cccaacggtt
     2761 tgttcttttt cttctatttt taagaccaca cggtccccta atggtttcaa catctgattt
     2821 cctccataat gagatagata ttattagcac tctttgaact ggagtgctaa ttcataattc
     2881 tattgtatca cttggtcaga aatagtcaag aaaaaagtct gactttctca agataaaaag
     2941 cctgagacca actcagactt tttaatgttt atactcaatg aaaatcaaag agcaaactag
     3001 gaagctagcc gcaggctgct caaagcattg ctttgaggtt gtggataaag ctaacgtggt
     3061 ttgaagagat tttcgaagag tattaaaatg gcaattcttc ctcttccaag accaaatctg
     3121 ccaaatcttg gcctgcatta ttttcacgca tggcacgttg agcacgactt tctaagagtt
     3181 ggaatcctgt cacaaggact tcgattacat agttcatctg accatttttc tcaaagcgac
     3241 gggtacgcaa ttctccatca acggaaatga gactaccttt ggttgcgtag cttgccaaag
     3301 tttctgctag tctgccccat aggaccatat tgacaaaatc agcttcacgt tcaccgtttt
     3361 ggtctttgta acgacggttg acagcgatag ttgctcgcgc taccgacttg tcattgttgg
     3421 ttttgtgcaa ttctggtgta gacgttaaac gcccaatcat gataacttta ttatacatat
     3481 tttcttcctc ctacttatct attcgtagga aatcaaaaaa gttacagaaa tttgtaactt
     3541 ttcgaggaaa tttcttattt tttatgaatc atgaaacctg tcgcctgttg attggccata
     3601 atggtcatat ctgtaatctg aacacggcga ggctgactgg tcacatagac tactgtgtct
     3661 gcaatatcct gagcttgcaa ggcttctatt ccttggtaaa cggacgcagc ccgctcttta
     3721 tcaccatgaa aacgaacagt tgagaaatct gtttcgacaa tcccaggctg aatggttgtc
     3781 accttgatat ccgttgcgat ggtatcaatt cgcagtccat ccgaaaaggt cttaaccgct
     3841 gccttggtag ctgagtaaac agcggcacca gcataggcgt agattcctgc ggttgacccc
     3901 atattgataa tatgaccttg attgactttt atcattgctg gcaagaaaca gtgagtaacc
     3961 gccatcagac ctttaacatt ggtatccaac atggtcaaca tatccaactc ctcatagtct
     4021 tgatagggag ccaagtcaag agccagtccg gcgttgttga ccaagatatc aatcctccct
     4081 atcgtttcta gaatatcaga gcaaacagtc ttcaccatga ccatatccgt cacatctagt
     4141 ggaaaagtcc agacggtttg atttggaaag cttactgcaa actccgactt gaggatttct
     4201 aatctgtcta tccgtcgtcc tgttagaacg acatcctcac cctgctccag ataagcacgc
     4261 gcaatcgctt caccgattcc tgaggttgct cccgtaatca ctacattttt tgccatctta
     4321 tttccttcta tcagatgctg acaagttcct aggcagtcca gtgtttcgct gggtcgaacg
     4381 gtgttccgac aacttggtct tctgataatt caagcacccc acgtttttgc ggagcatttg
     4441 gcaaatgcaa ttcacgagga ctacacatca tcccaaaact cttttcacca cgaagttcgc
     4501 ctgggaaaat gaaattccct tttggcatca tggcaccagg aagagccaca atggttttca
     4561 acccaacacg cgcattaggt gctcctgcaa cgatttgcac tatcttgtca cttgcgactg
     4621 caacttggca gatgttgagg tggtcactat ctggatgggc taccatctca acaatttcac
     4681 caacaacaaa cttaggttcc ttgtcattaa caatttcttc tgtaaaacct tccgcctgta
     4741 attcttggtt caaacaagcg acttgctcat ctgataaaaa gacttgacct cgctctgcaa
     4801 tttcaaacaa gctcgaaacc tcaaaaatgt tccaagctac tgtttcccca ttttctttga
     4861 ggaaaacacg ggctaccttg cctttgcgtt ccacattcag tttggcatct ccgctatttt
     4921 tcacgatgac cataaggaca tcaccgacat gttctttgtt atatgtaaaa atcattgttt
     4981 actttttctc ctatttcaat cctgctaaaa aatcgttaat ttgctcctta cttttacggt
     5041 cgcgattgac aaaacggccg atttccttgt ccttttctag aacaacaagg ctaggaattc
     5101 cgtaaacatc ccagagtttg gccaaatcca tatactgatc tcggtccatt cgaataaagg
     5161 tgaactctgg attggtctcc tcaatctctg gtaaggcagg atagatataa cggcaatcgc
     5221 cacaccagtc cgccacaaaa aggaagacct tcttaccgtc tttttctact aaagatgcca
     5281 attcttctaa acttgctggt tgtatcataa gacttcctcc tcatagacta ggtcttcatt
     5341 ttcatagaca aaagtataat gacggccatc ctcaaaaatg acgccaccaa gcaagctctc
     5401 tagactgctt tcatagactt gaacatagag ggtcgcaatt tcccccatgt ctgaaaaatg
     5461 gtctcgtaca atcgctgtca actcttcctg agtcttcatg agcttatggt catctgcaac
     5521 ttttttcgta gcaagggcaa ggctcccaat accaagcaga gccagacctg ccatccacat
     5581 ttttttagct ttcataccat tcattttaac acaaaaaagg ctttaggaca aatgaggaaa
     5641 cagcaaaaaa gcaagtaaaa agcctcttcc tttaaggaaa aggacttctt atactcaatg
     5701 aaaatcaaag accaaactag aaagctagcc gcaggctgct caaaacacgg ttttgaggtt
     5761 gtagataagg cgacgctgac gtggtttgaa gagattttca aagagtatta ttcttattgc
     5821 caggcaccta agttgccaac gtagtaacca tcaggtgtgt aggtattgcg aagcatctta
     5881 cctgatgaag ccagataata ctacttgcca ttgtctttga cccaatcatt cgcaatcatg
     5941 gaaccagaag aacttacata ataccattct cccttgtcat aaacccaagt actgactttc
     6001 atggttcctg agcaattaaa ggcaaaaaaa ctgtccaata tcattcgttt tttaaaagca
     6061 tttgacacta catcatctac gctgtagtac atagatacat caaacgtaaa agccaaaata
     6121 tcgaaaaata tacaactttt aaaggcagca tttcattttt taaagtctaa caaccataga
     6181 actgaaatca gagcaaggca tcaatttcct actcttagta cgtctatttt gatggttgaa
     6241 gtgaagattt ttttatttaa cgtagacaat ttccaacttc ccaaaagcca catctccacg
     6301 gatagtcaag gttttgctgg ttggggctac aggagcgtca gccttagctg caccaaagga
     6361 ggtttctact ttcaaatcta cacgccagtg ttgtggaaca tagacggttg catttccgaa
     6421 ggccacttca atatttaaag ttgcaaaatc acctagcatc tctgcattat catagtagat
     6481 tttagcatcc ccaaaagcga cttccacttg gtcatctacg agatcttgat cttgcttata
     6541 gaaggtcccg ctaccaaaag cgacttcctt atccgtgacg actgtttttt tcccattgta
     6601 ccaccatttt ttttcattcc agaacttact tgaatgcgtc agataaccaa caccaagtac
     6661 caccaagatg ctagcccaaa taagagaatg attggtaact ggtaacaagt cataagcgta
     6721 atttgcaatg atgagcgcca gtaaacctgt aaaaactgcc gaagtgagat gacgtctaag
     6781 gatggactca atggacttat aagcaaaaaa aacaatacct agtaaaggcc atattttacc
     6841 atccaaagaa ggaattccaa aattcccttg cagcaagatc caagctgcta aaaccaataa
     6901 aacaatacca aatgctttct ttttcatgtt ttttacctca tgtttcttag attttctttt
     6961 aggagggatt ggtaatgccg tgagacatga acctccttgt gcgtctgata aaaggaaatg
     7021 gtgcccgttc ctgaaaagga cttgtccact gagtaaatct gacggatgtt tgcgatcgtt
     7081 gacttggaaa ctcgattaaa atagcgaggc aagatagact ccaactcata gagcttgagg
     7141 cgaacctcat aagcttcctt ctggttatga gcgtagatct tgctcccttc tgtttcaaag
     7201 aagagaattt ctgacaggtc tagataatat tcacctgtcc ccttgtaaaa agtcaacctc
     7261 ggagcctttg actcttgcaa gagccgttgc aagtctgcaa tttcatctgt caaagtgggg
     7321 gtcttgatga caatttcagt ctcctctaaa ttgccgtcaa tctcaattcg taacttcatc
     7381 acatctcctt tctgactcta ctatatcaaa gctaagttag gaatacaagg gcaaaaaagc
     7441 aagtggtcaa tttgaagcag taagtggttg taggactagc ttaacttaca tgtcagaata
     7501 ggaagaaaag gaatccccac accaaaccac aagcatagcc aaccaagaca tccttgggat
     7561 aatgaacacc ccctaaaacc ctcaccaacc ccagcaaagc tgaaaagatc aagcatacta
     7621 agccaatagg tagactagca tgcagacagg ccatggagat gatagttgcc gaaaagacat
     7681 ggcgactggg catcgaccgt cccgaactat ccttatcaag aaggggacag atatcccaag
     7741 tttcataagg tctcgggtga ttgattttct tacgaaacag ggacaaggcc acaaaacctg
     7801 atgcaggaat aagcacataa accccaactt gctgaccaag tcctagttgc agataagtgg
     7861 tgactagcaa gatcagatag accaggggca tggcgactgt catcaaacga ttgaaactgc
     7921 gtaataggaa taaaagaatt ggacgactag ttagtctgga gctgatattt cgataccatt
     7981 cttgataatt tttcatttat gcttctcata cttttctaga acttgttgag atgttttccc
     8041 cttggcaagc caatccacta gcttgtccaa gcgacgtatt tcctgcatca gaggatcatc
     8101 aatttcctca atacggacac cgcaaatctt ccctgtaatt gcaattcgtt cagggacata
     8161 atatggtgct tgtctaaaaa aatctccgta agtaacatcc ctatccagac aagcaagaac
     8221 atcactcact tcataccctg tcaaccaact ggtcacttgg tgaactgact ctgcctttcc
     8281 accctttcgc tcaacttttg caatcaaggc taagtagaca gcagcaaatt tcatattgta
     8341 taatttctga ctcatacttc tctctttcta tgtgtactag tataaataag aaaaagaagg
     8401 ccgtcaagcc ttcttttgat ttattcttct gcttcatctt ctgtaaattg actattgtac
     8461 aagtcagcgt agaagccacc ttgcgccatc agttcctcat agttgccttg ctcgatgata
     8521 tttccatctt tcatgaccaa gatcaagtct gcatttcgga tggttgacaa gcggtgggca
     8581 atgacaaagg atgtgcgtca ttccatcaaa cggtccatgg ctttttggat caattcctct
     8641 gtccgtgtgt caacagaaga agtcgcctca tccaaaatca aaagcggtgc atccttaaga
     8701 agggcacgag caatagtcaa tagttgtttt tgtcctacag acaaggtcac ggtgtcatcc
     8761 aagatggtat catagccatc tggcaaggtc ataataaagt ggtgaattcc cacagcctta
     8821 ctagcttcca tcattcgttc atcactaatc cctatttgat tatagatgag attgtctcga
     8881 atagttcctt caaagagcca ggtatcctgc aagaccattg aaaaggcatc atgcacttct
     8941 gaacgcgtca tagccttggt atccacacca tcaatgcgaa tacttccctt atcaatctca
     9001 tagaatttca tcaaaagatt gacaatggtt gtcttaccag ccccagtcgg cccaacaatg
     9061 gcaacctttt gaccagcatg agctgtcgca gagaagtcat agtcttgaac attgacaccg
     9121 tccaccagaa tttctcctgc tgacacgtcg tagaaacgtg gaatcagatt gaccagagtt
     9181 gatttaccag aacctgttga cccaataaag gccactgttt gaccagtttc tgctttaaat
     9241 ctaacatgtt caataactgc ctccgaattt gccgcataac ggaaggtcac atccttaaac
     9301 tcgacctgac ctttgaagtt ttcatcagcc agctgcactt gagcagggtt ttggatagaa
     9361 gaatgcaaat ataaaacttg attaatccgc ttagcagaga ccatagttcg gggaagaacc
     9421 atgaagagtg ctcccacgag aaggaagccc atgacaacct acatggcata agacatgaaa
     9481 acaatcatgt cactaaagaa aggcagacgc gctatcggag cagcgtcgtt aatcacatag
     9541 gtcccaatcc agtaaatcgc cacactcaaa ccacttgaaa tccccatcat gataggattc
     9601 aaaatagcca taagacggtt gacaaacaaa ttcaaacggg tcaattcatc atttactgct
     9661 gcaaattttt cattttgata atcctctgca ttgtaggcac gaacgacacg aatacctgtt
     9721 aaactctcac gagtgatact gttcagttta tctatcagcc cctgaatcaa ggactgtttt
     9781 ggaaagtcta gcgtcatcaa aacggtcgtc atcaggacgt tgacaatcac tgccacaagt
     9841 acggcccaaa gccagtattc tgaatgacct aaaatcttcc caatagccca gatagccata
     9901 attggaccac gcgttaccac ttgcaagccc atagtaatca acatttgaac ttgagtaatg
     9961 tcattggtag tacgcgtcaa gaggctagga attgaaaatt tcttaatctc tgtctgcgag
    10021 taatccaaaa ctcggttaaa aatatcactt ctcagcctac tagtataaga agccgccact
    10081 cgggatgcaa aaaatccaac tgcaactacg gacaagaagg caagaaagag cattcccatc
    10141 atcatgcttg ccggctgcca caactcatct aaattagtta cttgactacc tagcaaatcc
    10201 gtaattttcg agatataggt cggcacttcc aactctagat agaccgaaaa gcaagtaaag
    10261 agaatggcta gtaaaatcat ccccattctt ttctactaat tcttttggct aatttcttta
    10321 ttctctcctc ctattccctt gatattttgc ctgtagttga ccgagaacct tctcaaaaat
    10381 cagtaattca tcttcatcaa tgtcttccat caactgcttg tctatgcgtt caaaaaaagc
    10441 cttaacctgt tgcatctgag aacgtgcttt gtccgtcaga cgaacaaact tagcccgctt
    10501 atcaacagga ctcgcctcca attccaccaa accattttgc actatacgct taaccagatt
    10561 actagcaaca gacttggtaa tattgagttc ctgctcgata tctttaatca agaccaagtc
    10621 ttggtttttc tcgcgattat ccaaaaaatg cacaacctga ccttgcggcc cacccataaa
    10681 ttcaatgccg caacgtttgg cttccttttg caccatcagg tgaatttgat gaccaaaacg
    10741 cttaaagact aacatcggtt tatccataat ctcccccttc taaataaaaa gagttctctg
    10801 gagaataatt aaatttctat gagaactatt ttcttgatta aaaaaatccc aagtgatttt
    10861 ctcacttagg atcatgttct ataggttaaa ttaaaaccca tctacgttcg tataaatctt
    10921 ttggacgtct tcgtcgtctt caagaacgct gtaaagtttt tcaaaggttt caaggtcttc
    10981 gcctgacaat tccacttctg actgaggaat catttccaat tcagtcactt ggaattcttc
    11041 aataccagac tcacggaggg caacgatagc cttgtgaagg tcagttggcg ctgtgtaaac
    11101 tgtgattgta ccttcttgtg cttctacgtc atccacatcc acatccgctt cgagcaattg
    11161 ctcaaagact gcgtccgcat cttcacctcc aaatacaata acacctttat tgtcaaagag
    11221 gtaagaaaca gaacctgaag cgcccatgtt tccgccgttt ttaccaaagg ctgcacggac
    11281 attggctgct gtacggttga cgttagaagt caaagtatcc acaattagca tagagccatt
    11341 tggcccaaaa ccttcgtaac gtccttctgt aaaggtttcg tctgtgtttc ctttggcttt
    11401 atcaatcgct ttatcgataa tgtgttttgg cacttgggct tgtttagcac ggtcgataac
    11461 gaatttcaaa gctgagtttg attctggatc tggatcacct tttttagctg ctacatagat
    11521 ttctacacca aattttgcat ataccttaga gttagctcca tctttagccg ttttcttggc
    11581 tacgatattg gcccatttac gtcccattag gaatctcctt ttttcacatt ttaatcttta
    11641 ttattataac acaagttttt ttgattttca ctagaggaaa tggattttat tagcaaatca
    11701 agctaggata gcactttacc tgctaagatg gtcttacctt tctatcttta tcaacagaca
    11761 ctcatccaca ttcaaaaaac aaactagacc attatctgca aatagaaagt ttcagccaag
    11821 tttgacaaag tcagctcaaa ttactgtttg aagtttgtag atataagcga caaaaacaat
    11881 catactgcac cttttgttga cagtctactc cagacatatc atagttcaag taaatacttt
    11941 gaaattcaac agttcttata ggcgctattg tattctaaga aatcaataga agagtttcta
    12001 agcaaacctc taatactcaa taaaaatcaa agagcaaacc agaaagctag ccgcaggttg
    12061 ctcaaaacac tgttttgagg ttgcggatgg ggctgacatg gtttgaagag attttcgaag
    12121 agtataattt acgtgttccc aagatggaga agttagacta gtacactggc acttctaaac
    12181 cattgctagc aattgatttg ttcatattta atttcatttt ttccataaat gggtattaga
    12241 tataaacagc aaaatatttc cgatacgtgt cgttcttgaa tttccaatca tctaaaacaa
    12301 gtaaaggata atcaatcccc tgtatatcaa ggaattggct acccttttta cttttttaca
    12361 cattctgttt gatagattca ttttaacatc acgagcatac tccaatggaa atcgctaggc
    12421 aagagataaa ctttcagata tccgcaaaga gatcatcgcc tctttttgtc gcaagcattc
    12481 tcctctccta gtcattttct accttatctt ctacctgagg atagagagtt gttccccaaa
    12541 tagaaatcgt ccgcttacgc actagtggca aatcggtttt ttcataaacc gtacgccacc
    12601 attcccaggc aagcccggta cactctctaa ttttgacaga gagattacga acattccctt
    12661 ttaaaggaat actagtggta aagtgagccg ttaaatcctg cccatttctg tcccaagcct
    12721 taggagtcaa gacttcctta ccttgatgat cataggataa ttcattccaa gtaatataat
    12781 attgggcaac ataggcacca ctatgatcca gcagtaaatc tccgtttctg taagctgtaa
    12841 ccttagtctc aacatagtct gtactatttt gaaaggtcgc aactacattg tcacgtaaaa
    12901 aagaagttgt ataggaaatc ggcaagcctg gatgatctgc tgtaaagcga ctgccttctt
    12961 gaatcaagtc ctctaccata tccaccttgc ctgttacaac tcgggcaccc gaacttgggt
    13021 cgccccctaa aataaccgcc ttcacttctg tattgtccaa aatctgcttc cactctgtct
    13081 gaggagctac cttgactcct tttatcaaag cttcaaaagc agcctctact tcatcactct
    13141 tactcgtggt ttccaacttg agatagactt ggcgcccata agcaacactc gaaatataga
    13201 ccaaaggacg ctctgcagaa attcctctct gttttaaatc ctctaccgtt acagtatctt
    13261 gaaacacatc tcctggattt ttaacagcgt ctacgctgac tgtataataa atctgcttaa
    13321 aattaacaat ctgaatctgc ttttcgcctg aatggacaga gttaaaatca atatcaagag
    13381 aattccctgt cttttcaaag tcagaaccaa acttgacctt gagttgttcc atgctgtgag
    13441 ccgtgatttt ttcatactgc attctagctg ggacattatt gacctgacca taatcttgat
    13501 gccacttagc caacaaatcg tttaccgctc cgcgaacact tgaattgctg gggtcttcca
    13561 cttggagaaa gctatcgcta cttgccaaac caggcaaatc aatactataa gtcatcggag
    13621 cacgatcgac cgcaagaaga gtgggattat tctctaacaa ggtctcatcc actacgagaa
    13681 gtgctccagg atagaggcga ctgtcgttgg tagctgttac agaaatatca cttgtatttg
    13741 tcgacaagct ccgcttcttt ctttcgataa caacaaactc atcgggtagc tgattaccct
    13801 ctttgatgaa acgattttca atactttctc cctgatgggt caagagtttc tttttatcgt
    13861 aattcatagc tagtataaag tcatttactg ctttatttgc catcttctac ctcctaataa
    13921 gttcctggat tgagttgcat aaactcagac ttgttcagcg aaatcagccg tggttggact
    13981 aagtgatcca aaatttcctc gtacaattct tctgagacat tgcgtcgccg tctggctaga
    14041 taagaagtcg gaataaccgt attatccaac ataaatacct tatctaagtc aatcaaggtt
    14101 ggtcttgtaa aaggattacg agctagatcc ggctcttcta tcataaagtt cttgaccaaa
    14161 cgtctggtca agagagctgg tttgaaggtc tgatttttaa ccaactcttt gtttttagtc
    14221 atgctgttgt caatacagat atacatatga ttcttcacag ccaaatcgct actaatagtc
    14281 ggaaaaggca aataaagaac tacaacatct cctctcttaa tcaagcaaga gcaccccctt
    14341 ttctcctaat gtaacataga caggattgac caagtcttct gattgactca gaatttccaa
    14401 agtttgagtt tggcgcgctg tcaatttagt agcatcttgt ctcttcaata caaaatgctt
    14461 gtcaccaata accttgacaa tataatcctt ctccaaagct gactggtaaa tccacatcag
    14521 atgttgtctg tcctgagaac tcaagagaga aggattttca agcctcccga tagtctgata
    14581 aaaatcaaaa acaggagcta actcctgcca atctgattgg ctagttgtca aggctagaaa
    14641 aagggctttg cgagctgata cttcttggtt agccttgaga gttactttcc cctccaagtt
    14701 ttttagaaat cgggaaactc cagaaagcaa atttttctct aactgcgaga aataaaaacc
    14761 tttcgttccc agacataagt ctttcatgtc gctttctcta gcaaataaga gctcaaacat
    14821 ttgatagtaa aagaaaaata tctggcactg ggtcgcgctc atcttttcct tatcggcttc
    14881 tttttttaac cagagcaagg gcgacaggta gctggattga gacatttcct ctacctccta
    14941 ctctttttta actggagcat ctgcactagc tgccacttct tttgactgga tactttccca
    15001 ctggttaatc tcctctgaga taagaccttc gcatgtcttg acaaataggg caaaagcctt
    15061 ggtctttcct gcatatttct ccgtttggca ttgatagagg aatttttctt tctccaggag
    15121 ttgcgcagtt ttttggtaag aaatccaatt ttcctttgca ttatacaaat tgataatccc
    15181 ctcacacagc aagccgagac tggataaggc aaccgaaatc aaacggtagc gatcacctgg
    15241 cataggaata gcacaaaaga cagctatgag gaaacctgcc acgatttctg ttatttttaa
    15301 taccttatag cgcctacgat gttgaacgct tttctttaaa aaatgagcta tctgtacgtc
    15361 taatcgctct gtcaggtaca tttcttctgg cgtcatattc gtaactcctt tcatttactt
    15421 tgataaccat agtataacat atttgaatat caaagtatag taaaaactgg actataactt
    15481 attagacttc ctgcgaaaca aaatatggta tagtagttct atgaattatg aagcaagtaa
    15541 acaactaact gatgcacgat ttaagcgtct tgttggtgtt cagcgtacca cttttgaaga
    15601 gatgttagct gtattaaaaa cagcttatca aaaaagtcag acaagctggt aaaatcttgg
    15661 ctgacagtgg ttatcaaggg ctcatgaaga tatatcctca agcacaaact ccacgtaaat
    15721 ccagcaaact caagccgcta acagttgaag ataaatcctg taaccatgcg ctatctaagg
    15781 agagaagcaa ggttgagaac atctttacca aagtaaaaac gtttaaaatg ttttcaacaa
    15841 cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgagtgct ggtattatca
    15901 atcatgaact aggattctag ttttgcagga agtctattat atatatgcac agacatatga
    15961 aatctttttg atacagcctt ctttttacat agagagacag cagttatgat atatttatcc
    16021 attcacaaca tcttctgtac caatactaca ataattggta cattttgatt acacaatcgt
    16081 ttcaaaaaat atgatggaag actgagtatt ttatagtaat tcccttccta tcaactagat
    16141 caaccagttg agtgttgaat gttgaaacac cctagcctca gcaaaggact atgatcagca
    16201 tttcctagcc aataggacgc tccaaatcac ctattctaag tccatcacta gcttggtcag
    16261 taagatacag actgcaaggc aagactgacg tggttgatga gattttggaa gagtattaca
    16321 atcatagatt caccagtaga cttgaccgca gatttaacta tagtagattg aaactagaat
    16381 agtacacttc tgcttctaaa acattgttag aaatcgattt gactgtcctg atcaatttgt
    16441 cctgttctcg tttcatttta ctatactaaa aaaccacctg aaacaaatca agtgactaga
    16501 ggataaaaac aaagactggg caaaaagttt tgaaaagcaa aaaacgcata atatcaggtc
    16561 ttgaaaaacc ttgatactat acgtttgatt gtgggaagat tgacttcatt ttctcctgaa
    16621 attgaagttt tttctagttt ccaggtatag acgaattcaa tatagccatc tcgctacaat
    16681 tattttaacc atcgaaaaaa tttttcagaa tttcaaaaat ttcattttga tctaatgaaa
    16741 tgtcatcatt ttgaagaata gttgacttca caagctctaa ttctatcaca aagcggtgca
    16801 tgtctgcttt taccgcacta cttgatgtta tagccgataa cttttcatct cctagcaagg
    16861 aagctgtcaa acgggtaagg tcattcaaat gctttttaat ggacttactt aaaccttgag
    16921 cacctgtagc agagcgttcc ctcatatcca gccaagcttt agccttaaaa ataattaata
    16981 ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggctgctcaa aacactgttt
    17041 tgaggttgta gatggaagct gacgtggttt gaagagattt tcgaagagta tagaccacaa
    17101 ttactcaata ccgaataccc ctgaatggtt tctttttcat gcaccaatat attataataa
    17161 tcttcatcca ataataaggc tgataaacta gcatcttggt caaaatgtaa gggaatttct
    17221 cgaccgtcct tctttaatgg atattctggt aagatactaa atagttcaat catagaagga
    17281 aactcaggat tagttgttgt aaatcgaaaa agctacgctt tctcatcttt ctgacttcct
    17341 tgatactctc ccaattctaa aaaatgattc aaggtagtat aaaattcctt attttttact
    17401 tcatcaatga tgaccatatc ataatctttt gttgtgcgac ttttaaatcc ttgcgaatcc
    17461 aatacgatag aggtagcagt tcccccaatc agaacataat agttctgaaa atccgcaaac
    17521 atttcttgaa aaataacttt cgtattagct ggcatcatct tctcccagat actgtaatat
    17581 catattttct agtgcttcac tctcttcctc tatacgtggg tcatcatcat cttttaaggt
    17641 caaataaaga gaaatcggat ctacaaattg tttatcatga ttatttttaa aatcattcca
    17701 aaactcagat acaaaaggac gatatttcca tatctctagc atctttcatt ttaaaacatg
    17761 ctgagaaagt ggcaaggata actgattgaa ttttctctgc catatgacat agctagtatt
    17821 ttcatccgtt tcagctaaaa aagttgaatg cgacaaagca taagcaccac catatagaag
    17881 gttagaaaca gattttatct gctttatatc gccatctggc aataaaaagg caatccacgt
    17941 taattgttcg ctaggtgtta attccttagg gacttcagta tcattcgcat tcagtactag
    18001 tcccaatgga gggaagaaga ggtttccctt aaagtctaca aacggaactc tagcttgaag
    18061 taattgcttt ttttcaccgt ctgataactt cgaaaacacc aaaacaacat ccatattggc
    18121 tttttcaccc atagtgcgag cctgagtaac aaatgaactc aaactccccc ttctcttttc
    18181 tttaatcaat aaaaatgatt ccttatgaaa agtcatttga gtatactcaa acctttttac
    18241 aaaactgatt ggtaaagtca aagtcagttc ctcaatactg acatcaacat aaaaggattg
    18301 aaaaattgac attatctttt tgacattcat gttttttcct tattctatca tttttattat
    18361 attttatcat tcggtataat aaaatataag ttttttgata aaataaccaa aaactactcg
    18421 ctatcccctc tcacattacc ctacatatcg tttgacatgc gactgatagt tcaggaaaac
    18481 ttcaaggaga acttttctct catccactat gcaggactta ctatttcact tctactccta
    18541 taggctcaat ttgacacttt tctttttcga attgctcata tgcctcctga atagtgagtt
    18601 cgatttatcc aaatttattt ttgtctattt tgatgaatac ttccacgaag atagtctgaa
    18661 aatgaatttg caccaatttt ccttctcttt ttaagcatat tattccagat atgattgccc
    18721 tcttgttcag taataaatta cgctttaaac gcttcaacca gtatatctcc tgttgtcata
    18781 tgttctaaag aaaattcttc tacatatggt ttaacatctc ttaggttatt acttcctaat
    18841 atcccattat gctttttcgc taaggaaata gaagccgctt ctcccttacc aataatcttg
    18901 ttactatcat gatttcttgt taaatctcta tataatgcgt attcttcagt tccaatgtct
    18961 atgctcacaa tctcagctga acccttagct accaactgat ctatcctaga ttttaaatgg
    19021 ggaattgtag gtatattgat ttcatcatac acctcttgtg gaataacaat tttacccaaa
    19081 tagagctttt ctaaaagatg ttcagcgcta acccataaaa atactgaaat acaatctgca
    19141 tcaataaata cacgactagt caaacgacaa ctcccccctc ttcatctagc ccatatacaa
    19201 tatcatatct gaaagcatct agtaacagtt cctcatactt cccctgcgaa attctgttat
    19261 tttctaaaag ttgttcagtt gaattaacat attatactaa tatcattttc tttttacttt
    19321 ctgacaaagg acgatataaa cttgtatcat agcctaatct tgaagctgtc tctataacac
    19381 taatatccat atttttaatt tcttctgcat caaggtatcc atcattcctc aatctatata
    19441 acatagcttt atgactgata ccataaaact gacccaattt tataatatct tctacttcaa
    19501 gatgagttct attggcattt tctctgattt cctcaaccat cctatacagt gaagatggga
    19561 aaattaaaaa ataagaagca aactgatccg cttttctttc agtttcatct ccttcaccaa
    19621 tcaagataag actgactgaa ctcttcttca cctcatcata ataaagatga tacagtccat
    19681 gtgctaaaga aaatctttac cttcctaatg gcatgtctga attgactgca atgagactga
    19741 actgagttcc tttataacag actccgctaa tattctttcc gagtccataa aataccagcg
    19801 tcaaattttc tatcttttgt accaatttaa aaatatctat cggcgattca ccatcagctc
    19861 ccaacttttt tctaagattt gaagctttat tacttaaatc cattcgtgat attcctttca
    19921 cctttttcca ttttggcaat catgctttga ttcaaagaca aatactcagc aatcttatct
    19981 tgagtaagat ttgaagatat tctaagttct tttattcttt ttccaacatc acatacattt
    20041 atcatattca tacacctctc ataaaaagaa tagcacactc ttgtcataat tttttaaata
    20101 aaaaaattat gacaaaacaa ggaagcaatt tattgatgct gcttaaaaat ctaagattga
    20161 tgagttccta tcaaaaatcg tatcttcaac ctcaaaacag tacttaaagc tatccgactc
    20221 ggtttacatt gtcaaattta gattttattt gagcataact ttctagtttg ctttctgatt
    20281 tttgtttaat atagtagcaa acattgaagg aaatatctcc acaaaaaaac gcatactatt
    20341 aagctttttc aagacctaat aatatgcgct gttctgattt gaaagacatt ccattattat
    20401 tttactgtaa tcaagccatc tggctctact gtgaattctg gcttgtctgc cagtgttccg
    20461 tctggtttga ggtagtacca gcctgttccg tccgctgact ggataaaggc atttgatacc
    20521 atggcgcctt ctttagcgtc taagtagtac caagtgtcct tgtacttgac ccagcctgtc
    20581 ttcatggcac cttcttcgtt gaaatagtac cacttatcag cgattttctt ccagcctgta
    20641 gccatttcgc ctgagttgtc gaaccagtac cagttgccgt ctgtgtgctt cctccagcgg
    20701 tctgcaagca tatagcctga actgtcaaag tagtaccaag tgccattgat tttctcaaac
    20761 ttgtcttttg gataagagcc gtctgaatgt acgtaccagt agccagtgtc attcttctgc
    20821 cagcctgttt caatcgtcaa gccgttctca atatcatact taaactgctc acggctaatg
    20881 ccccattttg ccaagtaagg gtatggatcc acatggtctg agtggttgtt tggttggtta
    20941 ttcgtgcaat actcgtgcgt tttaattcca gctaaactcc ctgtatcaag cgttttcggc
    21001 aaacctgctt catctgctag attgcgtaag agttcgatat aaaggcggta gtccgtcatg
    21061 aactcttctt tagttgaatg gctttcaatc agttcaaccg ctgcataggt ctcagcattc
    21121 caaccgcccc caacgtccca ggcaccatta tcaacaggtc ctacctgcat gatgcaaccg
    21181 ttcccaacaa tgtgcgagaa aaaacctaat tctgggtctt tccgccagtg ataatccgct
    21241 tcattctgta cggttgaatg cggattccca gttgagtgtg cgtgtacttg cctatatggt
    21301 tgcacgccga cttgaggcaa atctgttctt aatttactca cattaatttc catattctac
    21361 tccttatcaa ttaaaacaac tcatttttta caatccagaa ccagaaactc ctttatttct
    21421 accttacaaa gaagacaatc ttagtcacga ttaggcttgt agatagaacc tcaaaacgca
    21481 ctattttgac actgtaaata ggactgacaa ggtctgcatt ctatctacaa taacacccca
    21541 gactaaaaag cttttcaaaa gtatattttt acagtctcta tatgtccttt tcataaatac
    21601 tatactttat tatatcatat aaaagaagtc aaaagtctgt taaactattt tcaacaccaa
    21661 actaaagaag agaacacaag ttttttcgat gttcactaga ggaaatggat tttattcagt
    21721 aaatccaact aggattgcac tttggttgcc aaaattgcct ttccttcttt tatcaaggga
    21781 tgacggaata gtgagaagta cagttgaact gtcatggcaa cccagataag aggttcacaa
    21841 aggataacac ccttatatcc tgcccaagga ataatcaaaa ccacaaaaac gatttttccg
    21901 attagttcaa taaagctaga aactagagga aggatcttct gccccaagcc ctgcaagcaa
    21961 ttgcgataaa tcaacaagag gctcaaaatg ggataaaagg ctgaactgat ttgcagatag
    22021 agacttccat tttctatcaa gtaaccatct gtcgaactag ccaagaagga aaccaaggct
    22081 ggactggcaa aaaagaggaa aatacaaaca aaaactgccc aggatatact taaacgactg
    22141 ccgattcgaa gaccttgaac aatgcggtca ggtcgcttag ctcctagatt ctgagaagca
    22201 aaggtcgtca ttgatgcaga aatagcggtc ataggaagaa gggcaaaggt cataatgcgt
    22261 cgagctgccg tctgggcact aataatcact gcaccaaatg tattaacaga aaactgtaaa
    22321 atcacactgc cgatagatac aattgaactc atcaagccca tagccaaacc ttgctccaag
    22381 agatccgcgt acaagctttt gtcccatttg aaatgtttaa accgtggcaa gagttctggc
    22441 acacttttac gaatataata aaagcagaga accgctgata aaccttgcga aataatggta
    22501 gcaagtcctg cggattgaac tcccagatgc aattgcgtaa taaaatagag atccagaacc
    22561 acattaacca aggcagagaa aatcagaaat cccagggctg ctagactgtc accaatagac
    22621 cgcaacaagc ctgcaaaaag attataagca aagctgacac ctacacaggt cacaatcata
    22681 gaaatatatt gataagattg aggaagaatt tctgcaggag tatctaagta ttgcaagaga
    22741 ggatacaagc caagaaagcc cagcaacata actagaatgc tcaaaagagc acctaaaatc
    22801 caggtggctg ctactgcttc cttgatttta gtgaaattcc gagccccata ataacgagca
    22861 atgacaatcc ccatgccatt gccaacacca agtgtaaaac ctacaatcag gtcaaaaatc
    22921 gctgtcgtcg ctcctactgc agccaaggat tcttgaccaa gaaatcgtcc aacaatcaag
    22981 acatcagcag tgttatagag ctgttgaaaa atatttgata gcaagattgg aaaggtgaag
    23041 cttaagagcg agggaagaat cgaaccatgt atcaggtcca ctgttcgttt tttattcata
    23101 aagctattat atcagctttc cagaggagcg acaagaaaca gcaaacttat atatagcgga
    23161 atgaaataag gacagtcaaa tcgattttta acaatgtttt agaaatagat gtgtactatt
    23221 ctagtttcga tctattatag ttggttgagt ttggaatagt acgctgtagc tgctaaaaca
    23281 tttctagaaa ttaatttgac tttcctaata aagttgttca tatcttattt caagctacta
    23341 tatataatct aaaaacttga atcaaaaatc gaaaaagtag cggatttttc cactgcttta
    23401 acagcttatt cttcaatttc gatttcaagt tcatcgccta agtcaagcgt aacttcttca
    23461 ttcactgctt cttctttctt tggctcatct tttttgtttt cagtatcttg ttctgaaact
    23521 tcttctccat caatcaagcc aaatttagaa cggacttgct tatcaatttc atcaaagatt
    23581 tctgggtgct ctgccaagta tttcttagca ttctcagaac cttgcccaat tttttcatct
    23641 ttgtaagaat accaagcccc tgcttttttg ataatatcca aatcgcttgc aatcttcaaa
    23701 agctcaccag tcttagaaat tccttctccg tacataattt caactacggc ttccttaaac
    23761 ggtggagcta ccttattttt tacaacctta atcttagttt ctttaccgac attggtttct
    23821 ttttggtcac cagttccctt aatttgtgta ttaccacgaa catccaagcg gactgaagca
    23881 tagaatttca aagcacgtcc gcccggtgtt gtttctggat ttccaaacat cactccaact
    23941 ttttcacgca attggttgat aaaaatggca attgttttgg ttttattgat agaggcgcca
    24001 agtttacgca tggcctggct catcatacga gcctgcaaac caacatggct atctccgata
    24061 tctccatcaa tttccgcacg aggaacaagg gcagcaactg agtcgactac gacaagatca
    24121 actgcacctg agtcaatcag ttttcccgca atttcaagac cttgctctcc tgagtctggt
    24181 tgagacaaga gcaattcgtc aatattgaca ccaagggccg cagcataagc tggatcaagg
    24241 gcatgttccg catcgataaa ggcagcaatc ccaccttctt tttgcgcttg tgcaactgca
    24301 tgaagggcaa ccgttgtctt accagatgac tctgggccat agatttcgat gatacgtccc
    24361 ttaggataac cacctgagcc aagggcaatg tcaagagcta aagaacctga gctcatcact
    24421 tgcacctttt gctccgcacg ttcacccaaa cgcatgattg atcctttacc aaagtctttc
    24481 tcaatcaatt taagagcgtc attcaaggcc ttttcacgtt ctgccccaaa tttttttgaa
    24541 atttcttcta atttttttgg ttttttcgcc attctattct cctacattct aatgatcctc
    24601 agacctatct actattatat caaaagttag tcacttaata aagccttgcg aactaggtta
    24661 aaggcatgca taaccgcaat atgacgtaca tctgctcggc ttctgcctcc aatattaacc
    24721 ttgataacct cagttccttg ctcttgcgcc aagcctatga agactgtccc aactgggtgt
    24781 ccttctaggc tatctggtcc tgccactccg gtcaaactaa ttccaaaatc agactgggtc
    24841 ttgcttcgtg cctgctcagc catcttctga gctgtaaatt cagacaccac accatgttct
    24901 tccaaattct tggcaggaat atccaacatc cttgattttt cctccaagct ataggtcaca
    24961 aaaccaccct taaatatact tgaaactcca gaaaaattcg ccacggtagc ttggaaaaga
    25021 cctgccgtca aactctctgc agccgcgatg gttttccctt gccttttcag ttcttctacc
    25081 acaatgctgg ctaaactagt ttcttcccca taaccatagc aaaagtctcg taaagaaatt
    25141 ccttcgaaag tctggcagtc caagatttga ttttccaaga tatccagcgc ttgattcgcc
    25201 tcttcttgac tgctagcctt tgttgacaga cgtagagtga cttctcctgt cttggcataa
    25261 ggggccaagg taggatcgat ctgattatca attaaatcag ccaaaatcgt aaccaactgg
    25321 ctctcgccaa tcccaaagaa acgaagaact cgggaataca gcttgctccc tgtcatcaac
    25381 ttgggtagaa gttggtttaa gaccatgggt ttcaattcac ttggcggacc tggaaggacg
    25441 acataggtca ctccgtctac ttctaatttt cctccaacag ccagtcctgt ttcgtttggc
    25501 agtggaatcg ctccttctac aatttgagct tgtctttcgt tattcggtgt tcgggcatag
    25561 tctggtcgca gggcaaaaaa gatatccaac ttctcctgag cctgaggatc aaagactaat
    25621 gctttcccta aaaatttagc tagggtttgt ttggttaggt cgtcctcagt tggccccaaa
    25681 ccgcctgtca aaatcaccag actgctacgt tgactggcaa tctcaagcaa agacaagaga
    25741 cgaacttcat tgtctcctac agccgtctga aaatatacat ctaccccaat ctcagctagt
    25801 ttttccgaca aaaactgggc attggtgttg acaatctgtc ctgtcaaaat ctctgttcca
    25861 acagcaatga tttctgcttt catgtttcct cctacctatc tattcgtatt tttttgaaaa
    25921 aatcgcagga attttcctac gattgatttt tttatttgta tcaaaagtta attatcttca
    25981 tcaccaacag gtgctctgcc aaataaatct tcaaataaaa ccgcattggt ttcaagctga
    26041 gtaacttctt cttgtcccaa agaacgtcgg agtatatttt gcatttccaa catatgtgct
    26101 ctcgaaacaa tctggtaaga aacaccttga agtatctctc cttcaccctg caactgctga
    26161 gtttcaatgg ttttaaatga atctttatag cctagcaagt tagggatact ttttgcagac
    26221 aaatcaatat ttgtctgcat attgtcactc aaagctttta gaatctcttg ataatgacca
    26281 atgctattta aactgagagc tttttccatg actttttgaa taacttcacg ttgacgtttt
    26341 tgacgaccat aatccccctc aggatcttgg taacgcattc gtgcatagac tagggcttct
    26401 tctcccccaa tatgttgctc cccaacaccg atagaaatgg tattaaattc ttcttggtca
    26461 ctgatagaaa ttgggaaacc taggatatta ttgactgtaa tacctcctac tgcatccact
    26521 agtttttgca accctctcat attgaccatc acatagcgat caatatggat attcatcatt
    26581 ttttgaatgg tttctatagc aagctctgct ccaccatctg catatgctga gttcagtttc
    26641 gcttcatgag cctgaccatt ccctgattca atgcgcgtca gaatatcccg ctctaaactc
    26701 atcattgttg tttttttcgt tttaggattc actgtcatca agatcatgct atcacttcta
    26761 ccgacccaag tttcagttcg ttcagcattt ccggtgtcca ctcccattaa cagaatggtt
    26821 agaggttcag tcgcttcaat aaccttggtt tcttcgccga tttttttata ggttttagct
    26881 aaggtttctg tcccttgttg ataaatagta taagcaaaaa cacctactcc tactacagtt
    26941 acagaaagta aagctagcac cattccaata atttttttaa ccatatttct actaatctat
    27001 cagtttaccc atcaagtaaa catcgataaa tttcccttct tctatatatg ccccacgctc
    27061 ttggctacct tcaatgacaa agccatgctt ttgataaaga tggactgctg cttgattacg
    27121 agtttggaca gtcagttgga gacgacgcag aatgccactt gcttgtgccc actctatcgc
    27181 ttcttctagc aacaaacttc ccaagccatt attccaatat ctttttccaa tcacaatgaa
    27241 gagatctcca atatgacgga ctctcttacg ctgatcagct gtaatattta caataccagc
    27301 aattttgcca tttaagaatg caagtaaggt tatctgattg tccgaactag cttgcttgtt
    27361 gaggaatatt tccatctcct cactagtcaa gagaatacca tctccgtcta ggctggtaaa
    27421 gtctgtctcc aaactcacac gatttaaaaa ggccactaat tcagctgcat ctttgggctc
    27481 tgcttcccta atgagcaatt catactccat attgaagctc ctctaacaat ttctcagcac
    27541 gcaaaccctt tgcctgaaaa tttaaacggc gtccatctgc ttcttttaga atttccaatt
    27601 ctaaataagc atctggcaag gcatctccta agagatttcc ccactcaata acagtcacgc
    27661 cgccaccaaa gataaactca tccaagtcga tagaatcagc atctccttca atacgataaa
    27721 catctaggtg ataaagtgga agtcgacctt catactctct cacgatagta taggtgggac
    27781 ttttaatcat ttgagaaatc tgtaatcctt ttgcaagtcc tttagtaaag gtcgttttac
    27841 ctgcacccag ttctccagtt aagattaaaa catcattctt tgctaataga tggcccaaac
    27901 gctcccctaa ggcttgcaac tcttcttcat tttttgtgta catactctta ttataccaaa
    27961 aacttttctt ttgtgtctat tttcctacta aacttatcat cataacatcc atacaaaaac
    28021 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
    28081 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
    28141 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
    28201 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
    28261 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
    28321 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
    28381 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
    28441 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
    28501 tccagcacag attcctgaaa cgaaaaccat gcttccgatg aaaaaagctg tactttgttt
    28561 aaaggacaag atgcattcct tccataagaa acagctactc aaactgattt gaattaaagc
    28621 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
    28681 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
    28741 aacactagag actaatactc aatgaaaatc aaagatcaaa ctaggtagct agccacaggt
    28801 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
    28861 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
    28921 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
    28981 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
    29041 tatctagttc cttcaaataa ttttctatct tcatcaacat taaaggattg ttataaatct
    29101 tacataactc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
    29161 cgccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
    29221 tacagagttc aatcgtttca agagcttctt ggatggcttc attatatttt tcctttgata
    29281 ctaggtagtg agcgtagttg taacgaactc tgatgtagcc aaataaaaac tcttgatggt
    29341 ccaaattttt tgtctgatac aactctatta aatgagagta gtttgcctca tattcttgtt
    29401 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcagag
    29461 tatttgaaga gacttttaat aatatatttt ccaatgaaga aattgcctca cacttactgt
    29521 catattgata gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
    29581 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaatcg tcataatttc
    29641 tatcgtctaa tagtcgagca gacaattgct tgaaattaga gaggttagat ttaatttcaa
    29701 tttgttcatt aaaaaaataa tctaatggta cttcaagtcg ttgagagagt ttgaacaaaa
    29761 ggtctgcgga gggaatgaaa tgccctctct caattttact aatctggctt tgttcacaaa
    29821 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
    29881 ctgcgagtgt actcattaaa gataataaac cttcctattt gcttaattgc attata
//
LOCUS       DAVLUM010000026        29806 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLUM010000026 DAVLUM010000000
VERSION     DAVLUM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.026"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            143..1246
                     /gene="glf"
                     /locus_tag="VYN42_000971"
     CDS             143..1246
                     /gene="glf"
                     /locus_tag="VYN42_000971"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEV1462064.1"
                     /translation="MYDYLIVGAGLFGAVFAHEAALKGKKVKVIEKRNHIAGNIYTRE
                     EEGIQVHQYGAHIFHTSDKEIWEYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNK
                     LWGVVTPAEAQVKIEEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGKPT
                     TELPAFIIRRLPVRLTYDNNYFNDTYQGIPIGGYTQIVEKMLDHENIDVETNVDFFVN
                     KEQYLKDFPKIVFTGMIDEFFDYKLGELEYRSLRFENETLDMENYQGNAVVNYTDAET
                     PYTRIIEHKHFEFGSQAKTIITKEHSKTWEKGDEPYYPVNNDRNNHLYKSYKKLADEQ
                     GNVIFGGRLGHYRYYDMHQVIGAALQCVRNELN"
     gene            1567..3549
                     /locus_tag="VYN42_000972"
     CDS             1567..3549
                     /locus_tag="VYN42_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1462065.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGETGASKILRNIFVPPTFVQAEGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            3849..9152
                     /locus_tag="VYN42_000973"
     CDS             3849..9152
                     /locus_tag="VYN42_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1462066.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSQVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPEVAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKYGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPP
                     VAMTNYTKESMEALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(9319..11478)
                     /locus_tag="VYN42_000974"
     CDS             complement(9319..11478)
                     /locus_tag="VYN42_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEV1462067.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(11475..12071)
                     /gene="recU"
                     /locus_tag="VYN42_000975"
     CDS             complement(11475..12071)
                     /gene="recU"
                     /locus_tag="VYN42_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1462068.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            12137..12664
                     /locus_tag="VYN42_000976"
     CDS             12137..12664
                     /locus_tag="VYN42_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1462069.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            12734..13063
                     /gene="gpsB"
                     /locus_tag="VYN42_000977"
     CDS             12734..13063
                     /gene="gpsB"
                     /locus_tag="VYN42_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1462070.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            13084..13464
                     /gene="rnpB"
                     /locus_tag="VYN42_000978"
     ncRNA           13084..13464
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYN42_000978"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13549..14706
                     /locus_tag="VYN42_000979"
     CDS             13549..14706
                     /locus_tag="VYN42_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1462071.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKSLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            14719..16113
                     /gene="mapZ"
                     /locus_tag="VYN42_000980"
     CDS             14719..16113
                     /gene="mapZ"
                     /locus_tag="VYN42_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1462072.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLEDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     PASSNTTSELKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            16189..17613
                     /gene="gndA"
                     /locus_tag="VYN42_000981"
     CDS             16189..17613
                     /gene="gndA"
                     /locus_tag="VYN42_000981"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1462073.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            17625..18314
                     /locus_tag="VYN42_000982"
     CDS             17625..18314
                     /locus_tag="VYN42_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462074.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            18412..19428
                     /gene="cbpC"
                     /locus_tag="VYN42_000983"
     CDS             18412..19428
                     /gene="cbpC"
                     /locus_tag="VYN42_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1462075.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            19550..20428
                     /gene="mvk"
                     /locus_tag="VYN42_000984"
     CDS             19550..20428
                     /gene="mvk"
                     /locus_tag="VYN42_000984"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1462076.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            20410..21363
                     /gene="mvaD"
                     /locus_tag="VYN42_000985"
     CDS             20410..21363
                     /gene="mvaD"
                     /locus_tag="VYN42_000985"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1462077.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            21350..22357
                     /locus_tag="VYN42_000986"
     CDS             21350..22357
                     /locus_tag="VYN42_000986"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1462078.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLAIYGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIAAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            22341..23351
                     /locus_tag="VYN42_000987"
     CDS             22341..23351
                     /locus_tag="VYN42_000987"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1462079.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAETCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            23429..24127
                     /locus_tag="VYN42_000988"
     CDS             23429..24127
                     /locus_tag="VYN42_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1462080.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KIVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            24124..25119
                     /locus_tag="VYN42_000989"
     CDS             24124..25119
                     /locus_tag="VYN42_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1462081.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            25133..25765
                     /locus_tag="VYN42_000990"
     CDS             25133..25765
                     /locus_tag="VYN42_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462082.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVMVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            25766..26008
                     /locus_tag="VYN42_000991"
                     /pseudo
     CDS             25766..26008
                     /locus_tag="VYN42_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25933..26244
                     /locus_tag="VYN42_000992"
     CDS             25933..26244
                     /locus_tag="VYN42_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1462083.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            26269..26535
                     /locus_tag="VYN42_000993"
                     /pseudo
     CDS             26269..26535
                     /locus_tag="VYN42_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            26685..26879
                     /locus_tag="VYN42_000994"
     CDS             26685..26879
                     /locus_tag="VYN42_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462084.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYG"
     gene            27005..27830
                     /gene="cbpG"
                     /locus_tag="VYN42_000995"
                     /pseudo
     CDS             27005..27830
                     /gene="cbpG"
                     /locus_tag="VYN42_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            27849..28748
                     /locus_tag="VYN42_000996"
     CDS             27849..28748
                     /locus_tag="VYN42_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1462085.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGALKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGYWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYD
                     SGALAVNTTVGGYYLNYNGEWVK"
     gene            complement(28877..29806)
                     /locus_tag="VYN42_000997"
                     /pseudo
     CDS             complement(28877..29806)
                     /locus_tag="VYN42_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         9124 a         5318 c         6787 g         8577 t
ORIGIN      
        1 ggaaaaacta tttggtttta gttttatggg ttcatattta ctttttgcta tatttacttt
       61 aagtgttagt tttatcattg ttggaatgtt aatgaaaatt ccgtatttta atcgaatcgt
      121 caaattataa aaaggagaaa aaatgtacga ttatcttatc gttggtgctg gtctctttgg
      181 tgcagtcttt gcccatgaag cagccttaaa aggaaaaaaa gtaaaagtta ttgaaaaacg
      241 aaatcatatc gcgggtaata tctatactcg tgaagaggaa ggaattcagg ttcatcaata
      301 tggtgctcat atcttccata cttctgataa ggagatctgg gagtatgtaa atcagtttgc
      361 agagtttaac cgttatacca attctcctgt tgcaaactat aagggagaga tttataactt
      421 accttttaat atgaatacct tcaataaact ctggggagtt gtgacgccag cagaagcaca
      481 agttaagatt gaggaacaac gtgctatttt aaatggtaaa actcctgaaa atttggaaga
      541 acaagcgatt tctcttgtag gtacagacat ctacgaaaaa ttaatcaaag actatacaga
      601 gaaacagtgg ggcaaaccaa ctactgaact tccagccttt attattcgcc gtttgccagt
      661 acgtctgacc tatgataaca actattttaa cgatacctat caagggattc caattggtgg
      721 atacactcaa atagttgaaa aaatgttgga tcatgaaaat attgatgtag aaacaaatgt
      781 tgatttcttt gtgaataaag agcaatatct gaaagatttt cctaagattg tctttactgg
      841 tatgattgat gaattctttg actataagtt gggcgaacta gagtaccgta gtcttcgttt
      901 tgaaaatgag accttggata tggaaaatta ccaaggaaat gcagttgtga actatacgga
      961 tgcagaaacc ccatatactc gcattattga acacaaacat tttgagtttg ggagtcaagc
     1021 aaagactatc attactaaag aacattctaa aacatgggaa aaaggtgatg agccttatta
     1081 tccagttaat aatgatcgta ataatcattt gtataaatca tataaaaaac ttgctgatga
     1141 gcaagggaat gttatctttg gtggccgctt aggacactat cgttattacg atatgcacca
     1201 agtaattgga gcagctttgc agtgcgtgag aaatgagtta aattaatact caatgaaaat
     1261 taaagagcaa actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgcaga
     1321 tggaagctga cgcggtttga agagattttc gaagagtata aacaagtaaa actgactacc
     1381 agttattatt tagaaatagt attaaaaatt ccttgactat gtgatatagt tgagggattt
     1441 ttaaatgata ttcatatttt ttgcaaagat gttgtttgaa aaataatttt caaaaattct
     1501 gaaaattctg ttgacaactt tctgaaaaga gtctataatg gagagaaagt tttaaaggag
     1561 aaaatgatga aaagttcaaa actatttgcc cttgcgggcg tgacattatt ggcggcgact
     1621 actttagctg catgctctgg atcaggttca agcgctaaag gtgagaagac attctcatac
     1681 atttatgaga cagaccctga taacctcaac tatttgacaa ctgctaaggc tgcgacagca
     1741 aatattacca gtaacgtggt tgatggtttg ctagaaaatg atcgctacgg gaactttgtg
     1801 ccgtctatgg ctgaggattg gtctgtatcc aaggatggat tgacttacac ttatactatc
     1861 cgtaaggatg caaaatggta tacttctgaa ggtgaagaat acgcggcagt caaagctcaa
     1921 gactttgtaa caggactaaa atatgctgct gataaaaaat cagatgctct ttaccttgtt
     1981 caagaatcaa tcaaagggtt ggatgcctat gtaaaagggg aaatcaaaga tttctcacaa
     2041 gtaggaatta aggctttgga tgatcagaca gttcagtaca ctttgaacaa accagaaagc
     2101 ttctggaatt ctaagacaac catgggtgtg cttgcgccag ttaatgaaga gtttttgaac
     2161 tcaaaagggg atgattttgc caaagcgacg gatccaagta gtctcttgta taacggtcct
     2221 tatttgttga aatccattgt gacaaaatcc tctgttgaat ttgcgaaaaa tccgaactac
     2281 tgggataagg acaatgtgca tgttgacaaa gttaaattgt cattctggga tggtcaagat
     2341 accagcaaac ctgcagaaaa ctttaaagat ggtagcctta cagcagctcg tctctatcca
     2401 acaagtgcaa gtttcgcaga gcttgagaag agtatgaagg acaatattgt ctatactcaa
     2461 caagactcta ttacgtatct agttggtaca aatattgacc gtcagtccta taaatacaca
     2521 tctaagacca gcgacgaaca aaaggcatcg actaaaaagg ctctcttaaa caaggatttc
     2581 cgtcaggcta ttgcctttgg ttttgatcgt acagcctatg cctctcagtt gaatggagaa
     2641 actggagcaa gcaaaatctt acgtaatatc tttgttccac caacatttgt tcaagcagaa
     2701 ggtaaaaact ttggcgatat ggtcaaagag aaattggtta cttatgggga tgaatggaag
     2761 gatgttaatc ttgcagattc tcaggatggt ctttacaatc cagaaaaagc caaggctgaa
     2821 tttgctaaag ctaaatcagc cttacaagca gaaggtgtga ctttcccaat tcatttggat
     2881 atgccagttg accagacagc aactacaaaa gttcagcgcg tccaatctat gaaacaatcc
     2941 ttggaagcaa ctttaggagc tgataatgtc attattgata tccaacaact acaaaaagac
     3001 gaagtaaaca atattacata ttttgctgaa aatgctgctg gcgaagactg ggatttatca
     3061 gataatgtcg gttggggtcc agactttgcc gatccatcaa cctaccttga tatcatcaaa
     3121 ccatctgtag gagaaagtac taaaacatat ttagggtttg actcagggga agataatgta
     3181 gctgctaaaa aagtaggtct atatgactac gaaaaattgg ttactgaggc tggtgatgag
     3241 gctacagatg ttgctaaacg ctatgataaa tacgctgcag cccaagcttg gttgacagat
     3301 agtgctttga ttattccaac tacatctcgt acagggcgtc caatcttgtc taagatggta
     3361 ccatttacaa taccatttgc attgtcagga aataaaggta caagtgaacc agtcttatat
     3421 aaatacttgg aacttcaaga caaggcagtc actgtagatg aataccaaaa agctcaggaa
     3481 aaatggatga aagaaaaaga agagtctaat aaaaaggctc aagaagatct cgcaaaacat
     3541 gtgaaataac tgttgcaaaa tataagaaag gatttagtat ttctcttgaa tgctgaatcc
     3601 ttttttacat ttgtaaagaa agattctaaa tgtactgacc cccaaaagtt ggagcctctt
     3661 tttgtcagaa tagagaaaat ttttgttaat tttacttgtt tcctattgct ttctcagtta
     3721 ttatttgtta tattaaaagt ataattattt ttatttatca gggttaagca ttgcactttc
     3781 agaggaagga gtatttttta aaaagaaaat gtaaacgctt gctcaaaaat gaaaggattt
     3841 agaagtttat gaataaagga ttatttgaaa aacgttgtaa atatagtatt cggaaatttt
     3901 cattaggtgt tgcttctgtt atgattggag ctgcattctt tgggacaagt caggttcttg
     3961 cagatagcgt gcagtctggt tccacggcga acttaccagc tgatttagct actgctcttg
     4021 caacagcaaa agagaatgat gggcgtgatt ttgaagcgcc taaggtggga gaagaccaag
     4081 gttctccaga agttacagat ggacctaaga cagaagaaga actattagca cttgaaaaag
     4141 aaaaaccggc tgaagaaaaa ccaaaagagg ataaacctga agttgctaaa cctgaaacgc
     4201 ctaagacggt aacccctgaa tggcaaacgg tagagaaaaa agaacaacag ggaacagtca
     4261 ctatccgaga agaaaaaggt gtccgctaca accaactatc ctcaactgct caaaatgata
     4321 acgcaggtaa accagccctg tttgaaaaga agggcttgac cgttgatgcc aatggaaatg
     4381 caactgttga tttaaccttc aaagatgatt ctgaaaaggg caaatcacgc tttggtgtct
     4441 tcttgaaatt taaagatacc aataataatg tttttgtcgg ttatgacaag tatggctggt
     4501 tctgggagta taaatctcca acaactagca cttggtatag aggtagtcgt gttgctgctc
     4561 ctgaaacagg atcaacaaac cgtctctcta tcactctcaa gtcagacggt cagctaaatg
     4621 ccagcaataa cgatgtcaat ctctttgaca cagtgactct accagctgcg gtcaatgacc
     4681 atcttaaaaa tgagaagaag atccttctca aggcgggctc ttatggcaat gaccgtacgg
     4741 ttgtcagcgt taaaacagac aatcaagaag gcgtaaaagc ggatgatact cctgcccaga
     4801 aagaaacagg tccggttgtt gacgatagca aggtgactta tgatacgatc cagtctaagg
     4861 tacttaaggc agtaattgac caagccttcc ctcgtgtcaa ggaatacacc ttgaatggac
     4921 atactttgcc aggacaggtg caacagttca accaagtctt tatcaataac caccgaatca
     4981 cccctgaagt cacttataag aaaatcaatg agacaacagc agagtacttg atgaagcttc
     5041 gcgatgatgc tcacttaatc aatgcggaaa tgacagtacg cttgcaagtt gtggacaatc
     5101 aattgcactt tgatgtgacc aagattgtca accacaatca agtcactcca ggtcaaaaga
     5161 ttgatgacga aagaaaacta ctttcttcta ttagtttcct cggcaatgct ttagtctctg
     5221 tttctagtga tcaaactggt gctaagtttg atggggcaac catgtcaaac aatacgcatg
     5281 tcagcggaga tgatcatatc gatgtaacca atccaatgaa ggatttggct aagggttaca
     5341 tgtatggatt tgtttctaca gataagcttg ctgctggtgt ttggagtaac tctcaaaaca
     5401 gctatggtgg tggttcgaat gactggactc gtttgacagc ttataaagaa acagtcggaa
     5461 atgccaacta tgtaggaatc cacagctctg aatggcaatg ggaaaaagct tataagggca
     5521 ttgttttccc agaatacacg aaggaacttc caagtgctaa ggttgttatc actgaagatg
     5581 ccaatgcaga caagaaagtc gattggcagg atggtgccat tgcttatcgt agcattatga
     5641 acaatcctca aggttgggaa aaagttaagg atatcacagc ttaccgtatc gcgatgaact
     5701 ttggttctca agcacaaaat ccattcctta tgaccttgga tggtatcaag aaaatcaatc
     5761 tccatacaga tggtcttggg caaggtgttc tccttaaagg atatggtagc gaaggccatg
     5821 actctggtca cttgaactat gctgatattg gtaagcgtat cggtggtgtc gaagacttca
     5881 agaccctaat tgagaaggct aagaaatatg gagctcatct aggtatccac gttaacgctt
     5941 cagaaactta tcctgagtct aaatacttca atgaaaaaat tctccgtaag aatccagatg
     6001 gaagctatag ctatggttgg aactggctag atcaaggtat caacattgat gctgcctatg
     6061 acctagctca tggtcgtttg gcacgttggg aagatttgaa gaaaaaactt ggtgacggtc
     6121 tcgactttat ctatgtggac gtttggggta atggtcaatc aggtgataac ggtgcctggg
     6181 ctacccacgt tcttgctaaa gaaattaaca aacaaggctg gcgctttgcg atcgagtggg
     6241 gccatggtgg tgagtacgac tctaccttcc atcactgggc agctgacttg acctacggtg
     6301 gctacaccaa taaaggtatc aacagtgcca tcacccgctt tatccgtaac caccaaaaag
     6361 atgcttgggt aggggactac agaagttatg gtggtgcagc caactatcca ctgctaggtg
     6421 gctacagcat gaaagacttt gaaggctggc aaggaagaag tgactacaat ggctatgtga
     6481 ctaacctctt tgctcatgac gtcatgacta agtacttcca acacttcact gtaagtaaat
     6541 gggaaaatgg tacaccggtg actatgaccg ataacggtag cacctataaa tggactccag
     6601 aaatgcgagt ggagttggta gatgctgaca ataataaagt agttgtaact cgtaagtcaa
     6661 atgatgtcaa tagcccacaa tatcgcgaac gtacagtaac gctcaacgga cgtgtcatcc
     6721 aagatggttc agcttacttg actccttgga actgggatgc aaatggtaag aaactttcta
     6781 ctgagaagga aaagatgtac tacttcaata cgcaggccgg tacaacaact tggacccttc
     6841 caagcgattg ggcaaagagc aaggtttacc tttacaagct aactgaccaa ggtaagacag
     6901 aagagcaaga actaactgta aaagatggta aaattaccct agatcttcta gcaaatcaac
     6961 catacgttct ctatcgttcg aaacaaacca atcctgaaat gtcatggagt gaaggcatgc
     7021 acatctatga ccaaggattt aatagcggta ccttgaaaca ttggaccatt tcaggcgatg
     7081 cttctaaggc agaaattgtc aagtctcaag gggcaaacga tatgcttcgt attcaaggaa
     7141 acaaagaaaa agttagtctc actcagaaat taactggctt gaaaccaaat accaagtatg
     7201 ccgtttatgt gggtgtcgat aaccgtagta atgccaaggc gagcatcact gtaaacactg
     7261 gtgaaaaaga agtgactact tataccaata agtctctcgc cctcaactat gttaaggcct
     7321 acgcccacaa tacacgtcgt aacaatgcta cagttgacga tacaagttac ttccaaaaca
     7381 tgtacgcctt ctttacaact ggatcggacg tatcaaatgt tactctgaca ttgagtcgtg
     7441 aagctggtga tcaagcaact tactttgatg aaattcgtac ctttgaaaac aattcaagca
     7501 tgtacggaga caagcatgat acaggtaaag gcaccttcaa gcaagacttt gaaaatgttg
     7561 ctcagggtat cttcccattt gtagtgggtg gtgtcgaagg tgtcgaagac aaccgcactc
     7621 acttgtctga aaaacacgat ccatatacac aacgtggttg gaatggtaag aaagtcgatg
     7681 atgttatcga aggaaattgg tcactcaaga caaatggact agtgagtcgt cgtaacttgg
     7741 tttaccaaac catcccacaa aacttccgct ttgaagctgg taagacctac cgtgtaacct
     7801 ttgaatacga agcaggatca gacaatacct atgcttttgt agtcggtaag ggagaattcc
     7861 aatcaggtcg tcgtggtact caagcaagca acttggaaat gcatgaattg ccaaatactt
     7921 ggacagattc taagaaagcc aagaaggtaa ccttccttgt gacaggtgca gaaacagggg
     7981 atacttgggt aggtatctac tcaactggca atgcaagtaa tactcgtagt gattctggtg
     8041 gaaatgccaa cttccgtggt tataacgact tcatgatgga taatcttcaa atcgaagaaa
     8101 ttaccctaac aggtaagatg ttgacagaaa atgctctgaa gaactacttg ccaccggttg
     8161 ccatgactaa ctacaccaaa gagtctatgg aggctttgaa agaggcggtc tttaacctca
     8221 gtcaggccga tgatgatatc agtgtggaag aagcgcgtgc agagattgcc aagattgaag
     8281 ccttgaagaa tgctttggtt cagaagaaaa cggctttggt agcagatgac tttgcaagtc
     8341 ttacagctcc tgctcaggct caagaaggtc ttgcaaatgc ctttgatgga aacttatcta
     8401 gtttatggca tacatcatgg ggcggaggag atgtaggcaa gcctgcaacc atggtcttga
     8461 aagaagcaac tgaaatcact ggacttcgtt atgttccacg tggatcaggt tcaaatggta
     8521 acttgcgtga tgtgaaactt gttgtgacag atgagtctgg caaggagcat acctttactg
     8581 caactgattg gccagataac aataagtcaa aagatattga ctttggtaag acaatcaagg
     8641 ctaagaaaat tgtccttact ggtaccaaga cttacggaga tggtggcgat aaataccaat
     8701 ctgcagcgga actcatcttt actcgtccac aggtagcaga aacacctctt gacttgtcag
     8761 gctatgaagc agctttggct aaggctcaga aattaacaga caaagacaat caagaggaag
     8821 tagctagcgt tcaggcaagc atgaaatatg cgacggataa ccatctcttg acggaaagaa
     8881 tggtggaata ctttgcagat tatctcaacc aattaaaaga ttctgctacg aaaccagatg
     8941 ctccaactgt agagaaacct gagtttaaac ttagctcttt agcttccgat caaggtaaga
     9001 cgccagatta taagcaagaa atagctagac cagaaacacc tgaacaaatc ttgccagcaa
     9061 caggtgagag tcaatctgac acagccctct tcctagcagg tgttagccta gccctatctg
     9121 ctctctttgt agtaaaaacg aagaaagact agtatttagt aaaacctctt aacaagatta
     9181 cggaagcagt ctctatcttt tccaatgagg tttatagtac agaaaaagcc tgagaagatg
     9241 tcttctcagg cttttgttaa gcacataaat acaatagtgc tatgacaaaa tcacctagaa
     9301 aaatctgggt gataaatgtt atggttgtgc tggttgagga ttctgatttt gttgatcagg
     9361 ggttgtattt gattgttgcg tattattgtt aggattggta gtcgtactat tatttgtgct
     9421 tggagtggtt gagctagact gtgaagttga actatctgat gatgagcttg aactttcagt
     9481 tgatgggggt tgttgtggag caggtgagtt ccacgtagaa cgagcaccat ttttaaatac
     9541 gaattctcca tttctgtaga gcccctctgg tatattccaa tcttctggat tgcttccttc
     9601 agacaggtag gtcatcatag agcggtaaac tttggcagcg accgtaaggc cattgcctac
     9661 aagtggtgtc agacggttag aatagcctgt ccatacagcc attgaatatt tacgcgtata
     9721 gccagcaaat agttcatcag gtgctacaaa ttgagaggtc ttgatgtggt tttcaatttc
     9781 ctcgtctgta tagttagagg ttcctgtttt accagcctga ggaagccaag caagataggc
     9841 atttcgtcca gttccataag tcaagactgt tttcatcatg tcggtcatca tataggctgt
     9901 cgtttctttc atggcacgag ttccgacatt agagaactct ttttcactcc catcactaaa
     9961 gacgacttta tggatataca ttggtttata gtaagttcca ccatttgcaa aggcagcgta
    10021 agcagcagcc atcttttcac tacttgctcc atattttttg tctgattcgg ttgtgttact
    10081 tgaaatggca tttgagtagt gaatacttgg gtagtcgatt ccgagaccat ttaggaaagt
    10141 cttggcgcgg ttgagtccga ccttgtttag agtttccacg gctgggacgt ttcgcgattg
    10201 ttgcagggcg tattgcaagg tgatgttgcc aaagtagccc ctatcccagt tataaacagg
    10261 agtatttgtc ccagggtaat tatagggctc atcgtgaacg atagtagcag ttgaatcgta
    10321 gacaccgtac tccaaggcag gagcatagtc tgtgatcggt ttcatagttg atccccagtc
    10381 gcggtttgtt tctactgctt ggttaattcc gaaggaaaca ttacttgact gatggcgtgc
    10441 tcctagctgg gcaatgactt taccgttaga aacatcaaca atggtagaag cgacttgcaa
    10501 ttcatcgtct ggataggcaa cgtattcgtc tgtattgtaa atatcccaca gatgtttttg
    10561 agcttcttgg tctacatttg tgtagacatc catcccagtt gtgagcaggt tatagcctgt
    10621 ttcttcttca acttgattga tgacttcctt gaggtaatta tccatgtaag cagggtaatt
    10681 acttgctgat ttgagacttt gtagtccatc agtaattggt gtattgactg ctttctcata
    10741 ctgttcagca gagatgtagc cttgattttt catttcagat aagaccaagt ttcggcggtc
    10801 ttgggctgct tctggatgtg aataggggtc atattggttt ggtgcctgag gcattccagc
    10861 cagcaaggct aactgaggta aacttaaatt attgaggtct ttaccatagt agttttgagc
    10921 tgctgtctgc attccatagt tcccattaga catgtagacc ttatttatat agtaggtcaa
    10981 gatttcttgc ttggttgctt tttgttctaa ctgaatcgct aaccaagctt cctgagcctt
    11041 acgagaaata gtctggtcgg aagtcgaagt tgaaaagtaa gtcaacttaa tcaactgttg
    11101 ggtgagagtt gatccacctt ggagggaatt gctttgcaga ttgcgcaaga aagctcccag
    11161 gatacggatg gtatcaatcc ccctgtggtc gaagaagcga tggtcttcga tagaaacgat
    11221 tgccttaacc aaatctgtgg gaatatcatt agcttgggca ttgacgcggc gttcagaacc
    11281 caagtcagca atgagttgat ttttattgtc gtagatttta ctagaagttg ttgcaactag
    11341 tttactctcg gataggctag gagccttgct aacgtagtag aaaaaaactc ctccgcctaa
    11401 gacaatggct gcgataacca agcttaagaa gctaatgctc agatacttga ttaggcgcag
    11461 aatcgttggt ttgttcatct tgttttacca cctaataaat gttctttgat aacattgaga
    11521 taaggaattt gagggaaggc accagccttg atttcatatc catattctcg aatatattca
    11581 agtggcattg atttttgtcc cttatcttga tgatagaagc gaatcaaatc gaatgccggc
    11641 aataagtagg tttcttgctg agaagaaaag tgaagaagga caaagcagat tccttgttgg
    11701 gcaaggactt gttccatatg ctgaatctga tgtggatgaa aatttttcat cggaatcgca
    11761 cgtttttgtt ttgtttcctt gacttcaaag tcgatgtaat atccattata aacgccagaa
    11821 tagtccgtcg ttgaagcttg tcgaaaatag gcttcaacaa tcttggcacg acttcgttgt
    11881 ggatagtcca cttgtacgat ttgaatagga gttggtttct tatgtataac agccaagccc
    11941 tgagacaaat agtagtcgtt ggtagcattg atcatctttt caaaagacat tcctcgattt
    12001 gcgaaatttt tgggttgaga aagagatgtt tgtctttttt gtgatgaaac tttatgtgga
    12061 tagttgacca taattctcct tattggtaca ataacatcac tttattatac cataatttgc
    12121 acagaaaggg ttaaaaatgg ctacagcttt ggttttaggc tattctgctt ttgatttggg
    12181 tttattttct gataaggatc ctcgtcttaa attgattaaa aaagcgatac gtaaagattt
    12241 agaggctatg gcagcagatg gggtgtcttg gcttgtgttt acaggaagtt tgggttttga
    12301 atattgggtt ttagaggttg ctcaggagat gaaaaccgaa tacggtttcc agttggccac
    12361 catttttgct tttgaaaccc atggggaaaa ttggaatgaa ggcaatcaga tgaaactgag
    12421 tcgctttaag caggtagact ttgtcaaata tgcttatcct cgttatgaac acaaggggca
    12481 gttaagagat taccagcagt ttttgctgga aaacacgact agttcctatc ttttttatga
    12541 tgaagaaaat gaaacaaaac tagcttattt ttaccaaaag atgaaaaatc aagaggacta
    12601 ttttataaag agattaacat ttgatgaatt aaatgaactt gctgaaaatt tttccgaaaa
    12661 ttgaagcttt gaccttgatt tttgtttgcc tttttttata taataatact agcaagcgag
    12721 aatggagaga gacatggcaa gtattatttt ttcagcgaaa gatatttttg aacaagagtt
    12781 tggacgtgag gtccgtggct ataataaagt agaagttgac gagtttttag acgatgtcat
    12841 caaggactat gaaacctatg ctgccttggt caagtcactt cgtcaggaaa ttgcggattt
    12901 gaaggaagaa ttaactcgta aaccgaaacc ttcaccagtt caagcagaac cccttgaagc
    12961 ggcaattaca agttctatga cgaattttga tattttgaaa cgcctgaata gattggaaaa
    13021 agaagttttt ggtaaacaaa ttttagataa ctcagatttt taagtagtta tttgagatgt
    13081 gcaatttttg gataatcgcg tgaggagaat tgtttctcat gaggaaagtc catgctagca
    13141 caggctgtga tgcctgtagt gtttgtgcta ggcgaaacca taagcctagg gacgagaaat
    13201 cgttacggca gttgaaatgg ctaagtcctt ggataggcca gagtaggctt gaaagtgcca
    13261 cagtgacgga gtctttctgg aaacagagag agtggaacgc ggtaaacccc tcaagctagc
    13321 aacccaaatt ttggtcgggg catggagtac gcggaaacga acgtagtatt ctgactgcta
    13381 tcagctagag ctgttagtgg tagacagatg attatcgaag gaagtggtcc tagtcacttc
    13441 tggaacaaaa catggcttat agaaaattgc atataggttg gggctgagaa attttctcaa
    13501 cctcattttt taaagtggac atatagaaag gtcttgcaag actgtaacat gaaaaaagaa
    13561 tttaatttaa ttgcaactgt ggcagcaggg cttgaggctg tcgttggtcg tgaagtgcga
    13621 gagttgggct acgattgtca ggttgaaaat ggacgtgttc gttttcaagg agacgtgaga
    13681 gctattatcg aaaccaacct ttggcttcgg gcagcagatc gtatcaaaat tatcgtagga
    13741 acgttcccag ctaagacttt tgaagagcta tttcagggag ttttcgcttt agattgggaa
    13801 aattatttac cacttggagc tcggttcccg atttcaaaag ctaaatgtgt taagtccaaa
    13861 cttcacaatg agcccagtgt tcaggctatt tctaagaaag ctgttgtcaa gaaattgcag
    13921 aaacactatg ctcgcccaga aggggttcct ctgatggaga atggcccaga gtttaagatt
    13981 gaagtctcta ttctcaaaga tgtggcaact gtcatgattg atacgaccgg gtctagcctc
    14041 tttaaacgtg gttatcgtac cgaaaaaggt ggcgctccta tcaaggaaaa tatggcagca
    14101 gccattttac aactttctaa ctggtatcca gacaagtctt tgattgatcc gacctgtggt
    14161 tcggggactt tctgtattga ggcagttatg attgctagaa agatggcgcc aggtcttcgt
    14221 cgctcttttg catttgagga atggaactgg atcagcgatc gcttgattca agaagtgcgc
    14281 acagaagcag ctaaaaaagt agaccgtgag cttgagctgg atatcatggg ctgtgatatt
    14341 gatgctcgca tggtggaaat tgctaaggcc aatgctcagg cagctggtgt tgcaggagac
    14401 attactttta agcagatgcg cgtgcaggat ttacgttccg ataaaatcaa tggagtaatc
    14461 atttccaatc cgccttatgg tgaacgtttg tcagatgatg caggggtgac taagctctat
    14521 gctgagatgg ggcaagtatt tgcaccgctg aaaacttgga gcaaatttat cctgactagt
    14581 gatgaagctt ttgaaagcaa gtatggtagc caagcagata agaagcgtaa gttatacaac
    14641 ggaaccttga aagtggatct gtatcaatat tttggtcagc gtgtcaaacg gcaagaggta
    14701 aaatagaaag ggatactcat gagtaaaaaa agacgaaatc gtcaaaaaaa agaaggtcaa
    14761 gaaccgcaat ttgattttga tgaagcaaaa gagctaacag ttggtcaagc tattcgtaaa
    14821 aatgaagaag tggaagcagg agtcttgcct gaggattcca ttttggacaa gtatgttaag
    14881 caacacagag atgaaattga ggcggataag tttgcgactc gtcaatacaa aaaagaggag
    14941 ttcgttgaaa ctcagagtct ggatgattta attcaagaga tgcgtgaggc tgttgagaag
    15001 tcagaagctt cttcggagga agttccatct tctgaagaca tcttactacc cttgcctctg
    15061 gacgatgagg agcaaggctt ggatcctcta ttgctagagg atgaaaatcc aacagaaatg
    15121 actgaagaag tggaagagga gcaaaacctt tctcgtctgg atcaagagga ctcagaaaag
    15181 aaaagtaaaa aaggctttat tttgaccgtt ttggcgcttg tatcagtaat tatttgtgtc
    15241 agtgcttatt atgtctaccg tcaagtggct cgttcgacta aggaaattga aacttctcaa
    15301 tcaactacag ccaatcaatc agatgtggat gattttaata cactttatga cgccttttac
    15361 acagatagca ataaaacggc tttgaaaaat agccagtttg ataaactgag tcaactcaaa
    15421 accttgcttg ataaactgga aggtagtcgt gaacatacgc tagccaaatc taagtatgat
    15481 agtctagcaa cgcaaatcaa ggccattcaa gatgtcaatg ctcaatttga gaaaccagct
    15541 attgtggatg gtgtgttgga taccaatgcc aaagccaaat cggatgctaa atttacagat
    15601 attaaaactg gaaatacgga gcttgataaa gtgctagata aggctatcag tcttggtaag
    15661 agccagcaaa caagtacttc tagctcaagt tcaagtcaaa ctagcagctc aagctctagt
    15721 ccagcaagtt caaatacgac tagtgagcta aaaccaagta gttcaaatga gactagaagt
    15781 agtcgcagtg aagtcaatat gggtctctcg agtgcagggg ttgctgttca aagaagtgcc
    15841 agtcgtgttg cctataatca gtctgctatt gatgatagta ataactctgc ctgggatttt
    15901 gcggatggtg tcttggaaca aattctagcg acttcacgtt cacgtggcta tatcactgga
    15961 gaccaatata tccttgaacg tgtcaatatc gttaacggca atggttatta caacctctat
    16021 aagccagatg gaacctatct ctttaccctt aactgtaaga caggctactt tgtcggaaat
    16081 ggcgctggtc atgcggatga cttggactac taagcagtcg ttacaaaatt ctttcttttc
    16141 aaaagtaaaa atgataaaat aaaacaaatg aaacaagagg agtgtcaaat gacaaaagct
    16201 aactttggtg tcgtaggtat ggccgtaatg ggtcgtaacc ttgcccttaa tattgaatca
    16261 cgtggttaca cagttgctat ctacaaccgt agtaaagaaa aaacggaaga tgtgattgct
    16321 tgccatcctg aaaagaattt tgtaccaagc tatgacgttg aaagttttgt aaactcaatc
    16381 gaaaaacctc gtcgtatcat gctgatggtt caagctggac ctggtacaga tgctactatc
    16441 caagcccttc ttccacacct tgacaagggt gatatcttga ttgacggagg aaacactttc
    16501 tacaaagata ccatccgtcg taatgaagaa ttggcaaact caggtatcaa ctttatcggt
    16561 actggagttt ctggtggtga aaaaggtgcc cttgaaggtc cttctatcat gcctggtgga
    16621 caaaaagagg cctacgaatt ggttgcggat gttcttgaag aaatctcagc taaagcacca
    16681 gaagatggca aaccatgtgt gacttacatc ggccctgatg gagctggtca ctatgtgaaa
    16741 atggttcaca atggtattga gtacggtgat atgcaattga tcgcagaaag ctatgacttg
    16801 atgcaacact tgctaggcct ttctgcagag gatatggctg aaatctttac tgagtggaac
    16861 aagggtgaat tagacagcta tttgatcgaa atcacagctg atatcttgag ccgtaaagac
    16921 gatgaaggcc aagatggacc aatcgtagac tacatccttg atgctgcagg taacaaggga
    16981 actggtaaat ggacgagcca atcatctctt gaccttggtg taccattgtc actgattact
    17041 gagtcagtgt ttgcacgcta catttcaact tacaaagaag aacgtgtaca tgctagcaag
    17101 gtgcttccaa aaccagctgc cttcaacttt gaaggagaca aggctgaatt gattgaaaaa
    17161 atccgtcaag ccctttactt ctcaaaaatc atttcatacg cacaaggatt tgctcaattg
    17221 cgtgtagcct ctaaagaaaa caactggaac ttgccatttg cagatatcgc atctatctgg
    17281 cgtgatggct gtatcatccg ttctcgtttt ttgcaaaaga ttacagatgc ttacaaccgc
    17341 gatgcagatc ttgccaacct tcttttggac gagtacttct tggatgttac tgctaagtat
    17401 caacaagcag tgcgtgatat cgtagctctt gcggttcaag ctggtgtgcc agtgccaact
    17461 ttctcagcag ctattactta ctttgatagc taccgttcag ctgaccttcc agctaacttg
    17521 atccaagcac aacgtgacta ctttggtgct cacacttacc aacgtaaaga caaagaagga
    17581 accttccact actcttggta tgacgaaaaa taagtaggtc agccatgggg aaacggattt
    17641 tattacttga gaaagaacga aatctagctc attttttaag tttggaactc cagaaagagc
    17701 agtatcgggt tgatctggta gaggaggggc aaaaagccct ttccatggct cttcagacag
    17761 actatgattt gattttattg aacgttaatc tgggagatat gatggctcag gattttgcag
    17821 aaaaattgag tcgaactaaa cctgcctcag tcatcatgat tttagatcat tgggaagact
    17881 tgcaagaaga gctggaagtt gttcagcgtt ttgcagtttc atacatctat aagccagtct
    17941 ttatcgaaaa tctggtagcg cgtatttcgg cgatcttccg aggtcgggac ttcattgatc
    18001 aacactgcag tctgatgaaa gttccaagga cctaccgcaa tcttaggata gatgttgaac
    18061 atcacacggt ttatcgtggt gaagagatga ttgctctgac ccgccgtgag tatgaccttt
    18121 tggcgacact tatgggaagc aagaaagtat tgactcgtga gcaattgttg gaaagtgttt
    18181 ggaagtatga aagtgcgacc gagacaaata tcgtagatgt ctatatccgc tatctacgga
    18241 gcaagcttga tgttaaaggc caaaaaagct acattaaaac cgtgcgtggt gttggatata
    18301 ccatgcaaga atagaaaagc agttgcagtt gtgtaactgc ttttttgagg agtttttata
    18361 tattgacatg cagtcgggtc tttgctacaa tcgttttagg aggatatata gatgaaactt
    18421 ttgaaaaaaa tgatgcaagt tctactagca gtctttttct ttggtttgct agctacaaat
    18481 acggtatttg cgaataccac aggtggccga tttgttgata aggataatag aaaatattat
    18541 gtaaaagatg atcataaagc aatctattgg cataaaatag acggtaaaac ttactatttt
    18601 ggtgatattg gagagatggt tgtcggttgg caatacttag aaattcctgg aacaggttat
    18661 cgtgataatt tattcgataa ccaaccagtt aatgaaattg gccttcagga gaagtggtac
    18721 tattttggac aagatggtgc tttgctagaa caaacagata aacaagtact agaggcaaaa
    18781 acgtctgaaa atacaggaaa agtatacggt gaacaatatc ctctatctgc tgaaaagaga
    18841 acttattatt ttgataataa ttatgctgta aagacaggct ggatttatga agacggcaat
    18901 tggtattatt taaataagct aggaaatttt ggcgatgatt cttacaatcc actaccaatt
    18961 ggtgaagttg ctaagggttg gactcaagat tttcatgtta ctattgacat tgatagaagc
    19021 aaacctgctc catggtacta cctagatgct tcaggtaaga tgcttacaga ttggcaaaaa
    19081 gtaaacggaa aatggtatta ttttggctcc tctggttcta tggcaacagg ttggaaatat
    19141 gtacgaggca aatggtatta cttagataat aaaaatggtg atatgaaaac aggatggcaa
    19201 taccttggta acaagtggta ctacctccgt tcatcaggag ctatggtaac tggctggtat
    19261 caagatggtt taacttggta ctacctaaat gcaggtaatg gagacatgaa gacaggttgg
    19321 ttccaggtca atggcaaatg gtactatgct tatagctcag gtgccttggc agtgaatacg
    19381 accgtagatg gctattctgt caactataat ggcgaatggg ttcaataatg aaagaagcga
    19441 ttgcgaatgg aaacaatcgc tttttttgtg aaaatataat aaaatagata ggaaagaatt
    19501 aatacttgta tgaaaaataa gacgtttttt cgtctagtaa aaggaaaaaa tgacaaaaaa
    19561 agttggtgtc ggtcaggcac atagtaagat aattttaata ggggaacatg cggtcgttta
    19621 cggttatcct gccatttccc tgcctctttt ggaggtggag gtgacctgta aggtagttcc
    19681 tgcagagagt ccttggcgcc tttatgagga ggataccttg tccatggcgg tttatgcctc
    19741 actggagtat ttgaatatca cagaagcctg cattcgttgt gagattgact cggctatccc
    19801 tgagaaacgg gggatgggtt cgtcagcggc tatcagcata gcggccattc gtgcggtatt
    19861 tgactactat caggctgatc tgcctcatga tgtactagaa atcttggtca atcgagctga
    19921 aatgattgcc catatgaatc ctagtggttt ggatgctaag acctgtctca gtgaccaacc
    19981 tattcgcttt atcaagaacg taggatttac agaacttgag atggatttat ccgcctattt
    20041 ggtgattgcc gatacgggtg tttatggtca tactcgtgaa gccatccaag tggttcaaaa
    20101 taagggcaag gatgccctac cgtttttgca tgccttggga gaattaaccc agcaggcaga
    20161 agttgcgatt tcacaaaaag atgctgaagg gctgggacaa atcctcagtc aagcacattt
    20221 acatttaaaa gaaattggtg tcagtagcct tgaggcagac tctttggttg aaacagctct
    20281 tagtcatggt gctctgggtg ccaagatgag cggtggtggg ctaggaggtt gtatcatagc
    20341 cttggtaacc aatttgacac acgcacaaga actagcagaa agattagaag agaaaggagc
    20401 tgttcagaca tggatagaga gcctgtgaca gtacgttcct acgcaaatat tgctattatc
    20461 aaatattggg gaaagaaaaa agaaaaagag atggtgcctg ctactagcag tatttctcta
    20521 actttggaaa atatgtatac agagacgacc ttgtcgcctt taccagccaa tgtaacagct
    20581 gacgaatttt acatcaatgg tcagctacaa aatgaggtcg agcatgccaa gatgagtaag
    20641 attattgacc gttatcgtcc agctggtgag ggctttgtcc gtatcgatac tcaaaacaat
    20701 atgcctacgg cagcgggcct gtcctcaagt tctagtggtt tgtccgccct ggtcaaggct
    20761 tgtaatgctt atttcaagct tggattggat agaagtcagt tagcgcagga agccaagttt
    20821 gcctcaggct cttcttctcg gagtttttat ggaccactag gagcctggga taaggatagt
    20881 ggagaaattt accctgtaga gacagacttg aaactagcta tgattatgtt ggtgctagag
    20941 gacaagaaaa aaccaatctc tagccgtgac gggatgaaac tttgtgtgga aacctcgacg
    21001 actttcgacg actgggttcg tcagtctgag aaggactatc aggatatgct gatttatctc
    21061 aaggaaaatg attttgccaa gattggagaa ttaacggaga aaaatgccct ggctatgcat
    21121 gctacgacaa agactgctag tccagccttt tcttatctga cggatgcctc ttatgaggct
    21181 atggactttg ttcgtcagct tcgtgagaaa ggagaggcct gctactttac catggatgct
    21241 ggtcccaatg ttaaggtctt ctgtcaggag aaagacttgg agcatttgtc agaaattttc
    21301 ggtcagcgtt atcgcttgat tgtgtcaaaa acaaaggatt tgagtcaaga tgattgctgt
    21361 taaaacttgc ggaaaactct attgggcagg tgaatatgct attttagagc cagggcagtt
    21421 agctttgata aaggatattc ccatctatat gagggctgag attgcttttt ctgacagcta
    21481 ccgtatctat tcagatatgt ttgatttcgc agtggactta aggcccaatc ctgactacag
    21541 cttgattcaa gaaacgattg ctttgatggg agacttcctc gctgttcgcg gtcagaattt
    21601 aagacctttt tctctagcaa tctatggcaa aatggaacga gaagggaaaa agtttggtct
    21661 aggttctagt ggcagcgtcg ttgtcttggt tgtcaaggct ttactggctc tctataatct
    21721 ttcggttgat cagaatctct tgttcaagct gactagtgct gtcttgctta agcgaggaga
    21781 caatggttcc atgggcgacc ttgcctgtat tgcggcagag gatttggttc tctaccagtc
    21841 atttgatcgc cagaaggtgg ctgcttggtt agaagaagaa aacttggcga cagttctgga
    21901 gcgtgattgg ggattttcaa tttcacaagt gaaaccaact ttagaatgtg atttcttagt
    21961 gggatggacc aaggaagtgg ctgtatcgag tcacatggtc cagcaaatca agcaaaatat
    22021 caatcaaaat tttttaactt cctcaaaaga aacggtggtt tctttggtcg aagccttgga
    22081 acaggggaaa tcagaaaaga ttatcgagca agtagaagta gccagcaagc ttttagaagg
    22141 cttgagtaca gatatttaca cgcctttgct tagacagttg aaagaagcca gtcaagattt
    22201 gcaggccgtt gccaagagta gtggtgctgg tggtggtgac tgtggcatcg ccctgagttt
    22261 tgatgcgcaa tcaaccaaaa ccttaaaaaa tcgttgggcc gatctgggga ttgagctctt
    22321 atatcaagaa aggataggac atgacgacaa atcgtaagga cgagcatatc ctctatgctc
    22381 ttgagcagaa aagttcctat aatagctttg atgaggtgga gctgattcat tcttccttgc
    22441 ctctttacaa tctggatgaa atcgatcttt cgacagagtt tgctggtcga aagtgggact
    22501 ttccttttta tatcaatgcc atgactggtg gaagtaataa gggaagagaa atcaatcaaa
    22561 agctggctca ggtggcggaa acctgtggta ttttatttgt aacgggttct tatagcgcag
    22621 ccctcaaaaa tccaacggat gattcttttt ctgtcaagtc tagtcatccc aatctcctcc
    22681 ttggaaccaa tattggattg gacaagcctg tcgagttagg acttcagact gtagaagaga
    22741 tgaatcctgt tctattgcaa gtgcatgtca atgtcatgca ggaattactc atgcccgagg
    22801 gagaaaggaa gtttagaagc tggcaatcgc atctagcaga ttatagcaag caaattcccg
    22861 ttcctattgt cctcaaggaa gtgggctttg gaatggatgc caagacaatc gaaagagcct
    22921 atgaattcgg tgttcgtaca gtggacctat cgggtcgtgg tggcaccagc tttgcctata
    22981 tcgaaaaccg tcgtagtggc cagcgtgatt acctcaatca atggggtcag tctaccatgc
    23041 aggcccttct caatgcccaa gaatggaaag ataaggtcga actcttggtt agtggagggg
    23101 ttcggaatcc gctggatatg attaagtgct tggtttttgg tgctaaggct gtgggattgt
    23161 cacgaaccgt tctggaattg gttgaaacct acacagttga agaagtgatt ggcattgtcc
    23221 aaggctggaa agcagatcta cgcttgatta tgtgttccct taactgtgcc accatagcag
    23281 atctacaaaa agtagactat cttctttatg gaaaattaaa agaagcaaat gatcagatga
    23341 aaaaggcgta accagcgcct ttttttccat cctcagactg aggtgacttt tttgaattgt
    23401 gataaaatag aagggagagg atgaacctat gagaaaattt aaaatctttt tatttatcga
    23461 agcctgtctt ctgacaggag ctctgatttt gatggtatca gagcattttt cgcgttttct
    23521 gctgatacta ttcctctttt tgcttttgat tcgctactac actggtaaag agggaaataa
    23581 tcttctttta gtagcggcaa ccattctctt ctttttcatc gttatgctca atccttttgt
    23641 gattctagct atttttgttg cggttatcta tagcctcttt cttctttacc cgatgatgaa
    23701 ccaggaaaaa gagcagacca atttggtttt tgaagaggtc gtgacggtta agaaggagaa
    23761 aaatcgttgg tttggaaatc ttcatcattt ttcaagctac cagacttgcc aattcgatga
    23821 tatcaatctc tttcgcttca tgggcaagga cactattcat ctggagaggg tcatcttaac
    23881 caatcatgac aatgtcatta tcctcagaaa gatagtagga acgaccaaaa tcatcgtacc
    23941 tgtagatgtg gaagtcagtc tcagcgttaa ctgtctctat ggggatttga cttttttcaa
    24001 ccagcccaag cgagccctcc gcaatgaaca ctatcatcaa gaaacaaaag actatctcaa
    24061 gagtaacaag agtgtcaaga ttttcttgac cactatgatt ggtgatgtgg aggtggttag
    24121 aggatgaaaa aacaagccta tgtcattatt gctctcacct ccttcctgtt tgtctttttt
    24181 ttctcccaca gcttgctgga aatacttgat tttgactggt ctatcttttt gcacgatgtc
    24241 gaaaaaacag aaaaatttgt ctttttattg ttggttttca gcatgtccat aacctgtctc
    24301 ttagccctgt tttggcgagg gatcgaagag ctttctctaa gaaaaatgca ggctaatctc
    24361 aagcgtttat tggcagggca agaagtagtt caggttgtag atccagattt ggatgccagt
    24421 ttcaagtcct tatcaggtaa acttaacctt ttgacagagg ctcttcaaaa agcagaaaat
    24481 cagagtcttg ctcaggaaga ggaaatcatc gagaaggaac ggaagcgaat tgctcgggat
    24541 ttgcacgata cagtcagtca ggagttgttt gcggcccaca tgattttatc gggtatcagt
    24601 cagcaggctt tgaaattgga tagagaaaag atgcagaccc agttgcagag tgtcacagct
    24661 attttagaaa cagcccagaa ggatttgcgg gttttgctct tgcatttgcg accagttgaa
    24721 ctggagcaga agagcttgat agaagggatt caaattctct taaaagagct tgaggacaag
    24781 agtgatctta gggttagtct caagcagaat atgacgaaat tgcctaagaa aatcgaggag
    24841 catattttcc gtatcctgca agagttgatt agcaatacgc tccgccatgc ccaggcatct
    24901 tgcctagatg tctacctcta tcagacagat gttgaattgc aactgaaggt ggtggacaat
    24961 gggattggtt tccagttagg gagcttagac gacttgagtt atggactgcg aaatatcaag
    25021 gagcgggttg aagatatggc agggacggtt cagttattaa cagctcccaa gcaagggctg
    25081 gcagttgata tccgtattcc cctgttagat aaggaatgat aaaggagtaa agatgaaaat
    25141 tttactagta gatgaccatg aaatggtccg tttgggcttg aaaagctact ttgacctcca
    25201 agacgatgta gaagttgtgg gtgaggcgtc caacgggtct caagggattg acttggcctt
    25261 ggaactgcgt ccagatgtca tggtcatgga tattgtcatg cctgagatga atgggattga
    25321 cgcgacctta gcaatcctta aagaatggcc tgaagccaag attttgattg tgacctctta
    25381 tttggacaat gaaaaaatca tgccagtctt agatgctggt gccaaaggct atatgctcaa
    25441 gacttctagt gcagatgaat tgcttcatgc cgtcagtaag gtagctgctg gcgagctggc
    25501 cattgagcaa gaggttagca agaaggttga ataccaccgc aatcatatgg aacttcatga
    25561 agaattgact gcgcgtgagc gagatgttct ccaactcatc gccaagggct acgaaaatca
    25621 gcgcatcgca gatgacctct ttatctctct caagacggtc aagacccacg tgtccaatat
    25681 tcttgccaaa cttgaagtca gcgatcgtac ccaggcggct gtctatgcct ttcagcacca
    25741 tttggtgggg caagaggagt tttagatgag tttagcagat ttacttgagg agctagaagc
    25801 agcaaaagac tctaaaaaag caaggcccat ggaagcctat atgcgccatc aattttcttt
    25861 tctaggtatt gcggtgcctg aaagaaataa actctataaa aatatttact agaagcgaaa
    25921 aaaacaaaga ttatcgattg ggattttgca gacacttgct gggaaaagga gcctagaaaa
    25981 taccaatatg tggctgctaa ctatttgaaa gcaatgcagt cttatctaaa ggaaaccgat
    26041 ttgcctaagc tagagcagtt agtcgtgaca aaatcctggt gggacacggt agatatccta
    26101 gatcgagtag tagggagttt ggtgtatgaa caccctgaac tagaagaaat aatcttaata
    26161 ctcttcgaaa atctcttcaa accacgtcag ctctatctgc aacctcaaaa cagtgttttg
    26221 agcaatctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aaaatggagc
    26281 ctatcagata atatctggct gagacgtgtc gctattgacc accagttgtt aagaaaagag
    26341 aagaccaata ctcaattaat ggaaaagatt ctacttcata acttgaacca aacagaattt
    26401 tttatcaata aagccattgg ctggattctg cgagactact ccaaaacgaa tccaacttgg
    26461 gtaacatgct ttattgatga aaacaaggaa agaatggctg aacttagtat caaagaagca
    26521 agcaagtacc tctagcgtga ttgaaaagcg cagtcattaa ttgaaaagtt tgcctgttta
    26581 tgtgataatg gagggtattt aaagaaggtg gtagatttct tgattctata gtagattgag
    26641 aaatttagaa tagtacgcta taattacatt aggaggatac aataatgaag aaaactgttt
    26701 ataaaaaatt gggtatttca attattgcga gtactttatt ggctagccag ttatcgacag
    26761 tatctgcttt gagtgttatt tctagtacag gtgaagaata tgaggtaagt gagacactag
    26821 aaaaaggtcc agagtctaat gattcttcat tatctgagat ttcaccaacg tatggttaat
    26881 actaccaaaa gcaatcagaa gtattatcgg taatgatgat ttgattaaaa ttgataatac
    26941 tttacagtat ccatattcga cttcagctat ggttttatct aagtattatg gagtagccga
    27001 tggaatgaat gtagaaggga ggggaagtgc gaattttatt aaagataatg tgttaattac
    27061 agcggctcac aactactaca gacatgacta tgggaaagaa gcggatgata tttatgttct
    27121 tccggctgtt agtccaagtc aagaactatt tggaaagatc aaagtaaagg aagttcgtta
    27181 tttgaaggaa tttagaaatt taaattctaa ggatgcaagg gaatatgact tggctttatt
    27241 aattctagaa aagcccattg gtgcaaaatt agggactttg ggtcttccta ctagtcaaaa
    27301 aaatttgaca ggaataactg tgactatcac aggctatcca tcatataatt ttaaaattca
    27361 tcaaatgtat acagataaaa aacaagtttt aagtgatgat ggcatgttct tggattacca
    27421 agttgatact ttagaggggt ctagtggatc tacagtttat gatgctagtc accgtgtagt
    27481 aggagtgcat actttaggag atggagctaa ttaaattaac agtgcagtta aattaaatga
    27541 acgaaatttg ccatttattt atttattcgg ttcttaaagg ttactctctt gaaggatgga
    27601 agaaaataaa tggtagttgg tactattata gacaacatga taaacaaacg ggttggcagg
    27661 agataaatga tacttggtat tatttagaca gttccggtaa gatgcttaca gattggcaaa
    27721 aagtaaatgg aaactggtat tatctcaatt caaatggagc aatggttaca ggtagccaaa
    27781 ctatcgatgg taaagtttat aacttcgctt catctggtga gtggatttga tgttggagga
    27841 tatataaaat gaagcttttg aaaaaaatga tgcaagtcgc actagccaca tttttcttcg
    27901 gtttgctagg gaccagtaca gtatttgcag atgattctga aggatggcag tttgtccaag
    27961 aaaatggtag aacctactac aaaaaggggg ctctaaaaga aacctactgg agagtgatag
    28021 atgggaagta ctattatttt gatcctttat ccggagagat ggttgtcggc tggcaatata
    28081 tacctgctcc acacaagggg gttacgattg gtccttctcc aagaatagag attgctctta
    28141 gaccagattg gttttatttt ggtcaagatg gtgtcttaca agaatttgtt ggcaagcaag
    28201 ttttagaagc aaaaactgct acgaatacca acaaacatca tggggaagaa tatgatagcc
    28261 aagcagagaa acgagtctat tattttgaag atcagcgtag ttatcatact ttaaaaactg
    28321 gttggattta tgaagagggt tattggtatt atttacagaa ggatggtggc tttgattctc
    28381 gcatcaacag attgacggtt ggagagctag cacgtggttg ggttaaggat taccctctta
    28441 cgtatgatga agagaagcta aaagcagctc catggtacta tctagatcca gcaactggca
    28501 ttatgcaaac aggttggcaa tatctaggta ataagtggta ctacctccat tcgtcaggag
    28561 ctatggcaac tggttggtat caggaaggtt cgacttggta ctatctaaat gcaagtaatg
    28621 gagatatgaa aacaggctgg ttccaagtca atggtaactg gtactatgcc tatgattcag
    28681 gtgctttagc tgttaatacc acagtaggtg gttactactt aaactataat ggtgaatggg
    28741 ttaagtaatg aaggctaatt gtaaactgtg atggatactt aactttgtat aataggtgga
    28801 taaaagtctt cacaatcaaa aaacgcatag tatcaaggtt ttaggtgtac tgaccccaaa
    28861 aagttagaca aataatttat ccaaaggatt tagttctgta ctgcacagga ctaagtcctt
    28921 ttagttttac cttaattctc ttgttgttgt aataatcaat atagtctata atggcttgtt
    28981 ccaattgatt aagtgattta aatgttttct catagccata aaacatttcc gatttcagaa
    29041 tcccaaagaa ggactccacc atagtgtttc tctgtgaatg cctgttccaa cattgtttgt
    29101 acttgttcta agttgggtga agttgaaaga ttataggcga taatttcgct gttaaagcca
    29161 tctaaaactg gtgataagta aagcttttga gtacttgctg gaatggcaaa ttctgtcaca
    29221 tctgtgtagc acttttccat tgttttagag ccttcaaatt ggccttgaat gagattctct
    29281 gccttcttgc caacgtctcc tttatgagaa gaatattttc gtttctgtcg cattttagct
    29341 tgtaaattga gtacttttat caagccttga actcttttat gatttaccag ataaccacga
    29401 tttcttagtt ctaaatgaac ccggcgataa gtataatttc ccttgtgttc gataaaaatg
    29461 gattgaattt cagctttaag ctattggtcc ttatctggtt tatctagctg tttcaagtga
    29521 tagtagtagg tccaacgagc tagtttaatg gcttctagaa gaagatctaa cgaaaactca
    29581 gtcattaatt cttgaacaat ttctgtcttt cttctttctc tttttcctcc ttcaatcgga
    29641 gttctcttaa cttttttagg atggcattct ccgctctcag gtactctccc tcttgttttc
    29701 tcaacaatag tatacccgtt tttcctgtat tgtgctagcc agttaagaag catcgtacga
    29761 cttgggagac cgtattcaag agaaactcta tctttagtcc agcctt
//
LOCUS       DAVLUM010000027        27937 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLUM010000027 DAVLUM010000000
VERSION     DAVLUM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27937
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.027"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            395..1573
                     /locus_tag="VYN42_000998"
     CDS             395..1573
                     /locus_tag="VYN42_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1462086.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANLALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1887..2018
                     /locus_tag="VYN42_000999"
     CDS             1887..2018
                     /locus_tag="VYN42_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1462087.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2039..3589
                     /gene="dltA"
                     /locus_tag="VYN42_001000"
     CDS             2039..3589
                     /gene="dltA"
                     /locus_tag="VYN42_001000"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1462088.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQSLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3586..4830
                     /gene="dltB"
                     /locus_tag="VYN42_001001"
     CDS             3586..4830
                     /gene="dltB"
                     /locus_tag="VYN42_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1462089.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIATTLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGTIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALGISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4844..5083
                     /gene="dltC"
                     /locus_tag="VYN42_001002"
     CDS             4844..5083
                     /gene="dltC"
                     /locus_tag="VYN42_001002"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1462090.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5076..6344
                     /gene="dltD"
                     /locus_tag="VYN42_001003"
     CDS             5076..6344
                     /gene="dltD"
                     /locus_tag="VYN42_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1462091.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6499..6939
                     /gene="adcR"
                     /locus_tag="VYN42_001004"
     CDS             6499..6939
                     /gene="adcR"
                     /locus_tag="VYN42_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1462092.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6939..7643
                     /locus_tag="VYN42_001005"
     CDS             6939..7643
                     /locus_tag="VYN42_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1462093.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7636..8442
                     /locus_tag="VYN42_001006"
     CDS             7636..8442
                     /locus_tag="VYN42_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1462094.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8452..9957
                     /gene="adcA"
                     /locus_tag="VYN42_001007"
     CDS             8452..9957
                     /gene="adcA"
                     /locus_tag="VYN42_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1462095.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11117..11890)
                     /locus_tag="VYN42_001008"
     CDS             complement(11117..11890)
                     /locus_tag="VYN42_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1462096.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLPKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            12066..13469
                     /locus_tag="VYN42_001009"
     CDS             12066..13469
                     /locus_tag="VYN42_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1462097.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13584..14222
                     /locus_tag="VYN42_001010"
     CDS             13584..14222
                     /locus_tag="VYN42_001010"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1462098.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            14234..14674
                     /locus_tag="VYN42_001011"
     CDS             14234..14674
                     /locus_tag="VYN42_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1462099.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14667..15098
                     /locus_tag="VYN42_001012"
     CDS             14667..15098
                     /locus_tag="VYN42_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1462100.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15089..15559
                     /locus_tag="VYN42_001013"
     CDS             15089..15559
                     /locus_tag="VYN42_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1462101.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15584..16357
                     /locus_tag="VYN42_001014"
     CDS             15584..16357
                     /locus_tag="VYN42_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1462102.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16354..17154
                     /locus_tag="VYN42_001015"
     CDS             16354..17154
                     /locus_tag="VYN42_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1462103.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17213..19507
                     /locus_tag="VYN42_001016"
     CDS             17213..19507
                     /locus_tag="VYN42_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1462104.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTVFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19517..22633
                     /locus_tag="VYN42_001017"
     CDS             19517..22633
                     /locus_tag="VYN42_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1462105.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVINRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            22716..24482
                     /locus_tag="VYN42_001018"
     CDS             22716..24482
                     /locus_tag="VYN42_001018"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1462106.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMYMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLADLGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFLTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            24628..25779
                     /locus_tag="VYN42_001019"
     CDS             24628..25779
                     /locus_tag="VYN42_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1462107.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            25924..26808
                     /locus_tag="VYN42_001020"
     CDS             25924..26808
                     /locus_tag="VYN42_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1462108.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(26845..27003)
                     /locus_tag="VYN42_001021"
     CDS             complement(26845..27003)
                     /locus_tag="VYN42_001021"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462109.1"
                     /translation="MKIKEQTRKLATGCSKHRFEVVDKTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            27207..27458
                     /locus_tag="VYN42_001022"
     CDS             27207..27458
                     /locus_tag="VYN42_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1462110.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            27446..27736
                     /locus_tag="VYN42_001023"
     CDS             27446..27736
                     /locus_tag="VYN42_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462111.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         8795 a         4582 c         5914 g         8646 t
ORIGIN      
        1 attaactccc ctgaaattta ttttaattat gcaaatttca cgtatttttg atgctgagac
       61 gacgatcctg ggaacttttc agatattttt ttgactatct aaaatctatc attagaaaag
      121 cttagagcgc caaaggattt gagcgttttt ctgattttta agactttttc ccagtctctt
      181 tttcgattga agatgtaatt attctactaa ctaactaact tcttagtact agccaacaac
      241 gataatcata attcctccta aaattaggaa taataaaggc aatagttttt gttttttcat
      301 gtaaaaaacc tcacttttgt tttctgctat tttatgctaa aatattaaaa atcaaattta
      361 attccaaagt ttgtaactaa agggggagcg ctacatgtct aattcatttg tcaagttgtt
      421 agtctctcaa ttatttgcaa atttagcaga tattttcttt agagtaacaa tcattgctaa
      481 catatacatt atttcaaaat cagtaattgc cacatcacta gttcctatct taataggaat
      541 atcctctttt gttgcgagtc ttttagttcc gttggttact aaaaggttag cgctaaatag
      601 ggttttatct ttatctcaat ttggaaagac tatattattg gcgatactgg taggaatgtt
      661 taccgtaatg caatccgtag cgcctttggt gacctatcta tttgttgttg caatttccat
      721 actagatggt tttgcagcac ccgtttccta tgctattgtg ccacgctatg cgaccgattt
      781 gggtaaggct aatttagcct tatcaatgac tggtgaagct gttcaattga taggttgggg
      841 attaggtgga ctcttgtttg caacaattgg tctgttacct accacgttta tcattttagt
      901 cttgtatatc atttctagct ttctgatgtt atttcttcct aacgctgaag tggaggtgtt
      961 agagtcagaa actaatcttg aaattttgct caaaggttgg aagttagttg ctagaaatcc
     1021 tagattaaga ctttttgtat cagcaaattt attggaaatt ttttcaaata cgatttgggt
     1081 ttcttccatt atacttgttt ttgtaacgga gttattaaat aaaacggaaa gttactgggg
     1141 atattctaat acagcatact ctattggtat tataattagt ggcttaattg cttttaggct
     1201 atctgaaaag ttccttgctg ctaaatggga aagtattctt tttcctcttg tagctatggc
     1261 aatagtgaca ctgactattc tatattttcc aaacgcacag atgtttttat tattttcagc
     1321 tttagttggt atgttatcgc aactaaaaga agttcctgaa agtgtatttc ttcaggaaac
     1381 agtagaggaa aatcatttag ttaatgtcta ttccgttctt gaagtgattt ctacattagc
     1441 attttcagta tttgttttgc taatgagcta tattactgag agttttggta ttagcatcag
     1501 tttttggcta tcagccattt gtctgatgat agaagctatt ttaatttata tcagacgaga
     1561 ttattttaaa tgagagagtg gttaaaaagt ctttaaaaat cagaaaagcg catagtatca
     1621 ggtgttgaaa aaacttgata ttgtgtgttt tattatggga agatttactt cattgtctcc
     1681 tgaaatggag ttttgaagca ggatcactct atttgaaaat atacatagaa aaaccgcata
     1741 atccttaaaa taagctgaaa tctattggaa acatacggta aacaattgaa aagatactat
     1801 ataaagtggt acaatggtag aaaaataagc tagtaagaat cactcttatt ttagcgaaaa
     1861 attacagaaa tgaatggttt ttcttgatga aacagagaaa agaattgtac ctctttcttg
     1921 gtcggacagc cttgtatttt cttatctttc tagggctgct ttacttcttt agctatcttg
     1981 gtcagggtca aggaagcttt atctataatg aattttaact tgaaggagaa tccctattgt
     2041 gtcaaataaa ccaatagcag atatgattga aaccattgag cattttgctc agacacagcc
     2101 tagctatcct gtctataatg ttttggggca ggaacacact tatggcgatt taaaggctga
     2161 ttcggatagt ttggctgcag tcattgacca actaggcttg cctgagaagt ctcctgtggt
     2221 tgtttttggt ggccaagaat atgaaatgtt ggcaaccttt gtagcgctga ctaagtcagg
     2281 tcatgcctac attccaattg atagccattc ggccttggag cgagtttcag ctattttaga
     2341 agtagcagag ccaagcttga ttattgccat ttcagccttt cccttggagc aggtttctac
     2401 accaatgata aatctagctc aggttcaaga agcctttgcc caagggaaca actatgaaat
     2461 cacgcatcca gtcaagggag atgataatta ctacattatc tttacttctg gtacgactgg
     2521 taagcctaag ggagtgcaga tttcacatga taatctcctc agctttacaa actggatgat
     2581 tatggataag gaatttgcga caccgagtcg tccgcaaatg ctggcacagc caccttattc
     2641 ttttgacttg tctgtcatgt attgggcacc gaccttggca cttggtggta cgcttttcac
     2701 tcttccttca gtcatcactc aggactttaa gcaactcttt gcggctatct tttcattgcc
     2761 aatcgctatc tggacatcaa caccatcctt tgcagatatg gccatgttgt ctgaatactt
     2821 caacagtgag aaaatgcctg gagtcacgca tttctacttt gatggtgaag aattgacggt
     2881 caaaacagct caaaaactgc gcgagcgttt cccaaatgcc cgtatcatca atgcttacgg
     2941 cccaacagaa gcgacagtag ctctgtcagc agttgccgtg acagacgaga tgttagcgac
     3001 tctcaaacgc ctaccaatcg gctataccaa ggctgattct ccaaccttta tcattgacga
     3061 ggaaggaaat aaactgccaa atggcgaaca gggagaaatc attgtttctg ggccagctgt
     3121 ttcaaaaggt tatatgaaca atcctgaaaa aacagcagaa gccttctttg agtttgaagg
     3181 tctgccagcc tatcacacag gcgatgtggg aaccatgaca gatgagggct tgcttctcta
     3241 cggcggacgc atggacttcc agattaagtt taacggttac cgcattgagt tagaagatgt
     3301 ctctcaaagc ctcaacaagt ctcgctttat cgaatctgct gtcgcagtac cgcgctataa
     3361 caaggaccac aaggtacaaa atctattggc ttatgtcatc ttaaaagacg gtgttcgtga
     3421 gcagtttgag cgagatatcg atattaccaa ggccatcaag gaagacctga cagacatcat
     3481 gatgtcctac atgatgccat ctaaattcct ttaccgagac agtttgccac taactccaaa
     3541 tggaaagatt gacatcaaag gattgattaa cgaggtgaat aagagatgat ggagtttttt
     3601 caacagcttc ctcatttaga gccatatggc aatcctcagt attttgttta tgtgattgct
     3661 acaaccttgc ccatctttat aggcctcttt ttcaagaaac gctttgcctg gtatgaagtg
     3721 ttggtaagtc tcttctttat tgtcaccatg ttggtgggtg gaaagaccaa tcaactagct
     3781 gccttgggta tttacctttg ctgggaaata ttgctcctgc ttttctacaa gcattatcga
     3841 aaaagcaagg atggcaagtg ggtcttctac ttagttagtt ttctgtccct acttccgatt
     3901 atctttgtca aggtgcaacc agctatcaat ggaacgcagt ctttgcttgg gttcttggga
     3961 atttcttacc tgacctttcg ttcggttggg actatcatcg agctgagaga tggagtgatt
     4021 aaggatttta ccctctggga attcctccgt ttccttctct tcatgccaac tttctcgagt
     4081 ggtccaatcg atcgctttaa gcgatttaat gaaaattatc aggccattcc tgagcgagat
     4141 gagttgatgg atatgctgga tgaatctgtc cgctatatca tgtggggctt tttgtataag
     4201 tttatcctag ctcatgtttt aggagagacc ttactacctc ctctgaagaa tttagccttg
     4261 cagtcaggtg gcttctttaa tctctatgcc ttggcagtta tgtatacttt tggtctggag
     4321 ctcttctttg attttgcagg ttattctatg tttgctttgg gcatctcaaa cttgatggga
     4381 atccgtagcc ctatcaactt taacaagccc tttttatcaa gggatttaaa ggagttttgg
     4441 aatcgctggc atatgagtct gtccttctgg ttccgtgact ttgtctttat gcgaatggtg
     4501 atggtgttaa ccagaaagaa agtctttaaa aatcgtaatg taacctcaag catggcctac
     4561 attgtaaata tgctgattat gggattttgg catggtgtga cctggtacta tatcgcctat
     4621 ggactctttc atggactagg cttggtcatc aatgatgcct gggttcgcaa gaaaaaaacg
     4681 ctcaataagg aacggaaaaa agcagggaag gctgccctac ctgagaatcg ctggattcag
     4741 ttgcttggca tggttgtcac tttccatgtt gtcatgttgt cattcttaat cttttctgga
     4801 ttcttgaata atctatggtt taaaaaataa aaggaaataa aatatggata tcaaatcaga
     4861 agttattgaa attattgatg agttgtttat ggaagatgtt tctgacatga tggatgaaga
     4921 tctttttgat gcaggtgtct tggatagtat gggaacggtt gagttgattg tggagattga
     4981 gaaccgtttt gacattcgtg tccctgtaac agagtttggt cgtgacgact ggaatacagc
     5041 taataaaatc atagctggta ttgtggagct acaaaatgct taaacgctta tggatgatct
     5101 tcggaccggt cttgatcgct ggtttgttgg tttttctgct cattttcttt tatcctactg
     5161 agatgcatca taatctagga gctgaaaagc gttcagcagt ggctactact atcgatagtt
     5221 ttaaggagcg aagtcaaaaa gtcagagcac tatctgatcc aaatgtgcgt tttgttccct
     5281 tctttggctc tagtgaatgg cttcgttttg acggtgctca tcctgcggta ttagctgaga
     5341 aatacaatcg ttcctaccgt ccttatcttt taggacaggg gggagctgca tcgcttaacc
     5401 aatattttgg aatgcaacag atgttaccac agctggagaa taaacaagtt gtgtatgtta
     5461 tctcacctca gtggttcagt aaaaatggct atgatccagc agccttccag cagtatttta
     5521 atggagacca gttgactagt tttctgaaac atcaatctgg ggatcaggct agtcaatatg
     5581 cagcgactcg cttactgcaa cagttcccaa acgtagctat gaaggacctg gttcagaagt
     5641 tggcaagtaa agaagaattg tcgacagcag acaatgaaat gattgaatta ttggctcgtt
     5701 ttaatgaacg ccaagcctcc ttttttggtc agttttcggt tagaggctat gttaactacg
     5761 ataagcatgt agctaagtat ttaaaaatct tgccagacca gttttcttat caagcaatag
     5821 aagatgttgt caaagcagat gctgaaaaaa atacttccaa taatgagatg ggaatggaaa
     5881 attatttcta taatgagcag atcaagaagg atttgaagaa attaaaggat tctcagaaaa
     5941 gctttaccta tctcaagtcg ccagagtata atgacttgca gttggtttta acacagtttt
     6001 ctaaatctaa ggtaaacccg atttttatca ttccacctgt taataaaaaa tggatggact
     6061 atgctggtct acgagaggat atgtaccaac aaacggtgca gaagattcgc taccagttag
     6121 aaagtcaagg ttttaccaat atagcagatt tttctaagga cggcggggag cctttcttta
     6181 tgaaggacac cattcacctt ggttggttgg gttggttggc ttttgacaag gcagttgatc
     6241 ctttcctatc caatcccaca ccagctccga cttaccatct gaatgagcgc tttttcagca
     6301 aagattgggc gacttatgat ggagatgtca aagaatttca atagataata taatatagaa
     6361 gagttcaaga atgaaactag ttttcacgtt ttttcttgac tctttttttg cttgtgatat
     6421 aattaactgg taaacaaaat gtcaaagaat agtatttttc tcttaaaaaa gagaagtcta
     6481 aaaggaaagg agtcagatat gagacagcta gcaaaggata tcaatgcttt tttgaatgag
     6541 gtgattttgc aggcggaaaa tcagcatgaa atcctaatag gtcattgcac tagcgaggtg
     6601 gccctgacca atactcagga gcatatcctt atgctcttgt cagaggaatc tttaacaaat
     6661 tcagaattgg cccgtcgtct caatgtcagt caggcggcag ttaccaaggc cattaagtct
     6721 ttggtcaagg aagggatgtt ggaaacatct aaagattcta aagatgcgcg tgtgattttt
     6781 tatcagttga ctgacttggc tcgtccaatc gctgaggagc accaccatca ccatgagcat
     6841 acacttttaa cctatgaaca agtggcgact cagtttactc caaatgaaca aaaagtgatt
     6901 cagcggtttt tgactgcttt agtaggagaa atcaaataat gagatatatt acggtagagg
     6961 atttgtcctt ctattatgat aaggagcctg ttcttgaaca tatcaattat tgtgttgata
     7021 gtggggaatt tgttaccttg actggggaaa atggagcggc taagacgacg ctcatcaagg
     7081 ctagtcttgg aattctgcaa ccacgcattg gaaaggtggc tatttcaaag acaaatacgc
     7141 aaggtaagaa attgagaata gcctatcttc ctcaacaaat tgccagtttt aatgctggtt
     7201 ttccaagtac ggtctatgaa tttgtcaagt cgggtcgcta tccgagaaaa ggctggttcc
     7261 gtcgtttgaa tgctcatgat gaggagcata tcaaggctag tctggactca gttggcatgt
     7321 gggaacatcg agacaaacgc ttggggtctc tatctggggg acaaaagcag cgagcggtaa
     7381 ttgcgcgtat gtttgcttct gaccctgatg tgtttatcct agacgagccg acaacgggga
     7441 tggatgcagg aagtaaaaat gaattttacg aactcatgca ccacagcgcc catcatcatg
     7501 gcaaggctgt tttgatgatt acccatgacc ctgaagaagt taaggattat gcggatcgca
     7561 atattcatct agtccgtaac caagactcgc catggcgttg tttcaatgtt catgagaatg
     7621 gccaggaggt gggccatgct tagtttatta tcttacgact ttatacagcg cgcctttttg
     7681 gcggttattg ctatgagtct tttctcaccg gtattgggaa ccttcctcat cttgcgtcgt
     7741 cagagtttga tgagtgatac ccttagccac gtctcacttt caggtgtagc ctttggtctg
     7801 gttttgggga tttctccaac tgtttctact attgccattg tcttgattgc ggcggtcttt
     7861 ctggagtatc tccgtacggt ttacaagagc tttatggaaa tcgggacagc tatcctcatg
     7921 tcaacaggtc tggctgtttc tctgattgtc atgagcaagg gtaaaagctc gagttcaatg
     7981 agtttggacc aatatctctt tggttcgatc gtgactatca gtgaagaaca ggtcatttcc
     8041 ctctttgtca ttgcggcggt tgttttgatt ttgacctttc tctttcttcg tcctatgtat
     8101 atcttaactt ttgacgaaga tacggccttt gtggatggct tgccagttcg taccatgtcc
     8161 attcttttta acatggtgac aggggtggct attgccctta tgattcctgc agcaggagct
     8221 cttctggtat cgaccattat ggtcttgcca gctagtattg ccctgcgtct ggggaaaaac
     8281 tttaaatcgg ttatgctgct tgccagtgcg attggctttt tgggaatggt agcaggactt
     8341 tacatttcct actatgcaga aacacctgca agtgcaagta ttaccattat ttttgtaact
     8401 gtctttatac taatcagttt agtaagacgt tttatcaaat aggagacgaa cgtgaaaaaa
     8461 attagcttat tactagccag tctatgtgcc ttgtttttag tggcttgttc caatcaaaaa
     8521 caggcagatg gtaaactcaa tatcgtgaca accttttacc ctgtctatga atttaccaag
     8581 caagtcgcag gagatacggc taatgtagaa ctcctaatcg gtgctgggac agaacctcat
     8641 gaatacgaac catctgccaa ggcagttgcc aaaatccaag atgcagatac cttcgtttat
     8701 gaaaatgaaa acatggaaac atgggtacct aaattgctag ataccttgga taagaaaaaa
     8761 gtgaaaacca tcaaggcgac aggcgatatg ttgctcttgc caggtggcaa ggaagaagag
     8821 ggagaccatg accatggaga agaaggtcat caccatgagt ttgaccccca tgtttggtta
     8881 tcaccagttc gtgccattaa actagtagag cacatccgcg acagcttgtc agcagattat
     8941 cctgataaaa aagagacctt tgagaagaat gcagctgcct atatcgaaaa attgcaagcc
     9001 ttggataagg cttacgcaga aggcttgtct caagcaaaac aaaagagctt tgtgactcaa
     9061 cacgcagcct ttaactatct tgccttggac tatggactca aacaagtcgc aatctcagga
     9121 ctttctccag atgcagagcc atcagctgct cgcttggcag aattgacaga gtatgtcaag
     9181 aaaaataaaa tcgcctatat ctattttgaa gaaaatgcct cacaagccct tgctaacaca
     9241 ctttcaaaag aagcaggtgt caaaactgat gtcctcaatc ctttagaaag tctgacagaa
     9301 gaggacacca aggctggaga aaactacatt tccgtgatgg agaaaaacct caaggctttg
     9361 aaacaaacaa cagaccaaga aggcccagca atcgaacctg aaaaggcaga ggataccaag
     9421 acagtccaaa atggttactt cgaggatgca gctgtcaagg accgcacctt gagtgactat
     9481 gcaggtaact ggcaatcagt ttatcctttc cttgaagacg gcacgtttga ccaagtcttt
     9541 gactacaagg ctaagttgac tggtaagatg acccaggctg agtacaaggc ttactataca
     9601 aaaggctatc agacagatgt gactaagatt aacattactg ataatactat ggaatttgtt
     9661 caaggtggac aaagcaagaa atacacttac aagtatgtcg gtaagaaaat tttgacttac
     9721 aagaaaggca atcgtggcgt gcgtttcctc tttgaagcca cagatgctga cgctggacaa
     9781 ttcaagtatg ttcagtttag tgaccacaat gttgccccag ttaaggcaga acatttccat
     9841 atcttctttg gaggcacaag ccaagaagcc ctctttgaag aaatggacaa ctggccaacc
     9901 tactacccag ataacctatc tggccaagaa atcgcccaag aaatgttggc gcattgatga
     9961 gaaatcgact agttcataag agctagtcgg ttttttgata ctagatggct aacttcatta
    10021 tagacctttc agaactttaa acaataaata aaactcttga aatatctggg cttatatgct
    10081 agaatgtagt tagtgtataa ggttcattag aacaccaaag cccctaacta gtgccatagt
    10141 taagggcttt tttgacgtat cttagcgatt taacgggtgt ttataggcta gtcagtcggt
    10201 ctacttctta ccatctagcc atttgcagac gaaatacaag ataattccag ctataacatc
    10261 tgctataata gtaagagcaa gctctggtat aaggctcatt agtttcacct cctctcacga
    10321 acccatagga acgtaatcgg taaccgatga caaaagtatt atatcacact aaatttagat
    10381 catcaacctc acttaatgct tgaactattg tagattatat gctaaaatgt agttaattga
    10441 taaggttcat tagaacacca aagcccctaa ctatggccgt agttaagggc ttttttgacg
    10501 tatcttagcg atttaacggg tgtttatagg ctagtcagtc ggtctacttc ttactatcta
    10561 gccatctgca gacgaaatac aagataattc cagctataac atccgctata atagtaagag
    10621 cgagctctat gataaggctc attagtttca cctcctctca cgaacccata ggaacgtaat
    10681 cggtaaccga tgacaaaaat agtataccac aatacattta gatcatcaag gtcacttaat
    10741 tcttgaaata tagggtctag gcgacaaagt ctttaaaatc agaaaaacgt ataatatcag
    10801 gtgtgcaaaa acttgatact atgcgtttta ttgtgggaat atttgcccca tttctcctga
    10861 aattgagttt ttgtccagcc tctgtttttg gggttgctaa gaaaataatg tcatgtggtg
    10921 aatatttgta aatcagtcag cagacagaac gatactcttc gaaaatctct tcacatcatg
    10981 tcagcttcgt ctttccgtat atatgtgact gacttcatca gttctatcta caacctcaaa
    11041 acagtgtttc gagctgactt gatcaatttt caaatctgta ctttgagcaa gctgagacta
    11101 gcttcctatt tgattttcat tgaatatcag aaacccattc tccatcaaat aattcgactg
    11161 cgtctaataa tttttggtct ggcacggtgt cagaaataaa ggttgtgtat ttggggaggg
    11221 gattaatttt aaaaaatcca gtcttgtaaa atttagaact atcaatcagt aagatggttt
    11281 catgggcttt gtcaataata ttcttttttg aaatagcttg gctgagagaa gcttcataaa
    11341 catattgatc atcaatacct cttgctgaac aaaatgctaa atcgatatta aaatgatcta
    11401 ataaagaatt ttccttatca tagttgacca cggaacagga ttgatgtttg acctcgccag
    11461 atgtgataaa gattttggag ctatctttaa cagtttcaga tagggtttgt gcagtatgta
    11521 aaccatttgt aaaaataatc aaattatcaa gttcagaaag atagggacaa agttcgtaga
    11581 cagtagtact ggaatccaga taaacacaca taccagaccg aataaagtct ttagcgagac
    11641 tagcgattag tcttttttgc ctagtacttt ctccttcccg tatttgatga gaaagttcaa
    11701 ttgtgttcat agaggacagg gtcacgtatc cgtgctttct tttgataaga ccttgatttt
    11761 ctaagaaaat taaatcacga cgtaaggtac ttgtgctgga gaaagtgatt tctgccagct
    11821 cttttacggc aattcttttt ttctttttga taatttcaat caattcaagt acacgttcat
    11881 cttttatcat aagctcctcc taatttatca tttcaactat attatagcac aaattggagg
    11941 aatttgaatt atttttatga atattgggtt aacatttgaa cattattcaa gtaagcgttc
    12001 acatattgaa aaaataaaac gtggggatta taataaagtt aatcaaggac gaagagagaa
    12061 gaaaaatgga agcggtttta gcaatagatt taggtgcgac ttctggaaga gcaatcgttg
    12121 gttacctttc tgaaaataaa ctagtaatgg aagaaataaa tcgcttttct aatctaccta
    12181 ttagagtaaa agggcattta tcttgggata ttgactttct actagctaaa attcttgaaa
    12241 gtatccgctt ggctaatact agttacaaga ttttatctat cggtattgac acatggggag
    12301 ttgattttgg actgattgat aatgaaggta agctgttatc acaacctgtt cattatcgtg
    12361 atgaaagaac aaagggagtg ttaaaggaaa tatctgaaat gactgaatta gaaaaactgt
    12421 attcagagac aggaaatcag attatggaga taaatacctt gtttcaactc tttaaggcac
    12481 gtcaagaatc tcctgactct ttctataaga ccaataagat tcttttaatg ccagatttgt
    12541 ttaattatct cttgacaggt aagtttgcta cagaaaaaag cattgcttca acaactcaat
    12601 tatttgatcc taggagtcaa aattggaatc aaaatatctt aaaactattt gaattggatt
    12661 catctttact tcctgaaatt gtttcagagg gaaatgttct tggaaggata aaaaaggagt
    12721 atggtttagg cgatattcct gttgtgaatg tttgtagtca tgatacagca agtgcgattg
    12781 tctcagtacc taagacagaa ggtagtttat ttatttcatc aggtacttgg tctttggttg
    12841 gagtggaact tacttcaccg attcttacta ccgaatcctt cagttatgga tttacaaatg
    12901 aagtcggtaa agatggagtg attacatttc tgaagaattg tacagggttg tggatcatag
    12961 aggaactaag acgttcgttt gaacgaagag ggaaagccta ttcttttgat gatattagga
    13021 caatggtgga gaaagaaaaa gaaaatcttc ctctgattga tactgaatca actgaatttg
    13081 caacagaatc tgatatgcac aagactttga cagaatatct agcttatcat catgaaacta
    13141 gagagtggac agatggacaa ctatttaaga ttgtttatga aagcctagct gaaacgtata
    13201 ggaaagcgat agagttacta gaagaactaa ctcataaggt ttataagagg atatatgtga
    13261 ttggaggagg tgctagagcc agttatttta accaaatgat tgctgataga actggtaaag
    13321 aggttcttac aggtttgact gagggtacag ctgtggggaa tattgttgtg cagctcatag
    13381 ctatgggaca attaaaaggg atggaagaag ctcaccatgt tattgaggag ttcctacaat
    13441 tagagagtta ttactcccaa aagaattaaa aagattgaga gtttgtaaat ttgcctccct
    13501 cccccttctt aagttttgta caagaagggg ggataattgg tgaattgaaa aatatttagt
    13561 gttttgatat gaggaggata agaatgtcag atgtaaaaca agaattaatt aagtatggca
    13621 agaagctggt agaaacagat ttgacgaaag gaacaggtgg gaatctcagt gttttcgatc
    13681 gtgaaaaaca attgatggca attaccccgt cgggtattga tttctttgaa atcaaagaat
    13741 ccgatattgt agtgatggat attaatggaa atgttgtaga gggagaacgc ttgccatcta
    13801 gcgaatggta tatgcatttg attcaatatc aaactcgtga tgatatcgat gcaattatcc
    13861 atgctcatac aacttatgca acagtattag cttgtctcag agaaccactt ccggcgagtc
    13921 attatatgat tgcagtggca gggaaagatg ttcgggtagc tgagtatgca acatatggta
    13981 cgaaagaatt ggctgtgaat gcagctaaag caatggaagg tcgtagagca gttttactag
    14041 cgaatcatgg aattttagca ggtgcacaaa atttattgaa tgcatttaat attgttgaag
    14101 aagttgaata ttgtgcaaaa atttattgtt tagctaagaa ttttggagag ccagtagttc
    14161 ttcctgatga ggagatggat ttaatggcag aaaaatttaa aacatacggt cagagaaaat
    14221 agggaggata ttaatgttaa aacatatacc gaaaaatatt tctccagatt tattgaagac
    14281 tttaatggaa atgggacatg gagatgaaat agtattagct gacgcgaatt atccttctgc
    14341 ctcatgtgca aataagctaa ttcgttgtga tggtgtaaat attccagaat tattagattc
    14401 cattctgtat ttaatgccat tagatagtta cgtcgatagt tcaattcagt ttatgaacgt
    14461 tgtttcgggt gatgatattc ctaagatatg gggtacctat agacagatga ttgaaggtca
    14521 tggtacagat cttaaaacga ttacttatct tagaagagaa gacttttatg aacgtagtaa
    14581 gaaagcttat gctattgttg ctacaggaga aacttcactt tatgctaata ttatccttaa
    14641 gaaaggagta gttgttgaaa gagaaaatgt ttaatagagg aattttagtt gccagtcatg
    14701 gtaattttgc tagcggagct ctcatgaccg cagaaatgtt tgttggtgag acaacaaatg
    14761 atagagttag gacattaggt ttgatgcctg gagagaatat tgtagagttt gagcattatt
    14821 ttaaaaatca agtggatgaa ctgttagact caaatcaaga ggttatcgtt ttgactgact
    14881 tgattggagg aagtcctaat aatgtggctt tgtcacggtt tttaaatttg gattcagttg
    14941 atattgtaac agggtttaat atccctctcc tagtggaatt aatatcaagt tatgattcaa
    15001 aaatcaattt agaagaaatt gttcacaatg ctcaaaatag tttgtttaat gttaaacaac
    15061 aacttaacgt agaggaggaa gaagatttat gtctatagag tttgttcgta ttgatgaccg
    15121 tctggtacat ggtcaagttg tcactacgtg gctaaaaaag tatgatattg agcaagttat
    15181 cattgttaat gatcgcatct cagaagataa aacacgacaa tctattttaa agatttctgc
    15241 accggtaggt ttaaaaattg ttttctttag tgtaaaacgg tttgtggaag ttttaaactc
    15301 tgtgccaata aaaaagagaa caatgctgat atatacaaat ccaaaagatg tgtatgattc
    15361 tattgaagga aatttaaaat tggagtacct caatgtagga cagatgagta aaacggagga
    15421 aaatgaaaag gtaacgggag gtgtagctct aggtgaagaa gacaaatatt attttaagaa
    15481 aatagttgat aagggaacga gagttgaaat tcaaatggtt cctaatgata aagttacaat
    15541 gttggaaaaa tttttataaa aataatttaa ggaggtacag tatatgctat tcacacaagc
    15601 attactggtg acattagttg ggattattgc cactattgac tataatggac cgttatttat
    15661 gattcaccgt ccgttagtta caagtgcaat ggttggctta gtattaggag atttcaccca
    15721 aggtgttctt attggttcag ctcttgaatt aacttggctc ggtgtaacag gtattggagg
    15781 ttatactcca ccagatacta tttcaggtgc gattattggt actgcatttg gtattttatc
    15841 tggtcaagga gaaactgctg gtatcgctat agcagttcca attgcagttg ctacccaaca
    15901 gttggatgtt cttgcaaaaa ctttagatgt ttattttgtg aaaaaagctg ataatgatgc
    15961 taaaaacgga gattattcaa agatcggttt ttatcattat tcaagtttgg ttttaatcac
    16021 gttatttaaa attgtaccaa ttttcctagc tattatgctt ggaggggaat atgtggcaga
    16081 cttgtttgct aaggttccac caatcgttat gcagggactt aactctgcag gtgctttact
    16141 accttcaatt ggttttggta tgcttttaaa tatgatgctc aagaaaaata tgtgggtatt
    16201 cttgttgatt ggattcattt gttctgtgta tggaggaatg tcaaccattg ggatctcact
    16261 agttggtatt gcggtagcat acttctacga tatgattgga agcaaaccac aagaaacaac
    16321 ttcaagtagt gatgttgagg aggatcttga tctatgatga ataataaagt aactaaagtt
    16381 gaacttaaaa aagttttcaa acgaagtttt atgtatggtt cttcatggaa ctatgagaga
    16441 atgcagaacc taggttttct atatacaatt cttccagtat tgaaaaaact atacccagac
    16501 aaagattcag cttctcctgc aatgaaacgt caccttgagt ttttcaatac tcatcaaaca
    16561 gcggcaccat ttattcttgg agttacttcc gctatggaag aacaagaagg aaatgaaggt
    16621 gcagcttcaa ttactggtat taaagttggc ttgatggggc cactggctgg tctaggagat
    16681 agtttgttct ggctgacact agttcctatc tgttttagta ttggtgcgtc ttattctaaa
    16741 gacggcggtg ctttaggtat ctttatcgcc ttaatattgt ttaatattat taatattcct
    16801 gttaaatatt tcggtttgaa atatgggtat actaagggtt ctagtcttat ccaagaaaat
    16861 aatacaaaag gaacattgaa tcgcgttacg agtatggcga cagcattagg gctagtacta
    16921 gtgggtggtt tgattccatc aatggttggt attaattttg gattagaatt taagcagggg
    16981 gaacttgtta tttctgttca agaaatgatt acaaaattaa ttccaggatt tatccctatg
    17041 gctttgactt tattaatgtg taaattaatt agaaaaggaa agaatccggt tgtactaatc
    17101 tttagtgtta tggctattgg agttattcta gttgttttag gaattttgaa gtagtagaaa
    17161 gtgtggaggt ggtatttggg atatcacctc cattttggaa gagaggtaaa gagtgaaatt
    17221 atggtataag aaagctgccg caaattggaa tgaagccttg ccgattggga acggtcattt
    17281 aggtggtatg atttatggtt cagctacaaa agaatgtatt caactaaacg atgagactat
    17341 ttggtataga ggaaagtcag atagaaataa tccagactca ctattgcatc ttaaaaaaat
    17401 tcgggaatat cttttagatg gagaaattca gaaagccgaa gaattgataa agttaacagt
    17461 gtttgctacc ccaagagatc aaagccacta tgaattactt ggggaacttt acattgagca
    17521 tatagatatt cagtcttgtg ctctttcatt gtatgaaaga gagctagatt tagatacagc
    17581 tatttctaat gttgtgtttg agcctaatag ttgtaattta caaataaaaa gagaatattt
    17641 tacgagtttt aataagaata ttttatgttg ccgtatagtg tcatcagttc aaaacacatt
    17701 aaatttaaac attaatttgg gtagaaataa acggtttaat gacgaagtat ctaaactgga
    17761 ttcaagtaca attttaatgt cggcctctgc tggaggtaga aaaggtgttc agtttaaagt
    17821 agtatgtcat tctaaggtta cggatggtga agtaagtgta ttgggagaga caatagttat
    17881 tcggaatgct acagaggtat ttctttatct caaatcaatg acggattatt ggggaaatat
    17941 agatatttct tctcttcagg gagaatttag tagtattgat tactttacag aaaaagatga
    18001 acatgtaaaa aaatatcagg agcaatttaa tagagttgat tttaaactag actatagtaa
    18061 aggttgtctt agcattccaa cgaatctact tcttgaaaac actaaaaagt atagtaacta
    18121 cttgactaac ttgttatttc attatggaag atatctgtta atatcgtcta gtcaaccgaa
    18181 tggtttacct gccaatcttc aaggaatatg gtgtgatgaa ttaaatccaa tttggggttc
    18241 taaatatacg attaatatta atactcaaat gaattattgg atggtaggtc catgtgattt
    18301 accagaagta gaatatccat tatttgatat gctcgaaaga atgagagaac cgggaagact
    18361 aaccgctaag aaaatgtatg gagctagagg ttttacagca catcataata cggatggttt
    18421 tggcgatacg gctccccaat ctcatgccat gggggctgca atttgggtat taactattcc
    18481 atggttatgt actcatattt gggaacacta tttatatttc caagatgagc gtattcttac
    18541 ggaacatttt gaaatgataa aagaagcatt tcttttcttt gaagattatt tatttgaggt
    18601 ggatggctac ttgatgacag gtccaagtgt ctcaccggaa aataaatatc gcttaaaaaa
    18661 tggtattgaa ggaaatgctt gtctatcatc tacaattgat aatcaaattt taagatattt
    18721 ttgtgattca tgcattggaa ttgcaaaaca attaggagac aattcggatt ttattagtcg
    18781 tgtgaaggag ttaaaaaaga aattacctag aacaaaaata ggtagtaatg ggcaaataca
    18841 agaatggcta gaggattatg aagaagtaga gcctggtcat agacacattt cacctctatt
    18901 tgggctttat ccttataatg agattgatat tcataaaact ccggaattag cagaagcagc
    18961 taaaattact atcaatagga gattatcaaa cgctaacttt ttatcttcac aggataggga
    19021 gcaagcgatt aataattggt tagtaagtgg tttgcatgct agtacacaaa caggttggag
    19081 tgctgcatgg ctgattcatt tttttgcgag actatatcaa ggtgaacctg cttataacca
    19141 gattaatggt ttgttaaata atgcgactct tggcaattta tttcttgacc atccaccatt
    19201 tcaaattgat ggtaatttag gtttggtgag tggaatttgt gaattattag tacagagcca
    19261 tcataattgg ttatcactaa ttccagcttt accttctgct tggtcagaag gagaagtgaa
    19321 aggtttcaga gtaagaggag gatataaggt atcgtttgct tggaaaaatg gggatataac
    19381 attcctaaaa ttggaaggag gaaacaaaga tcaaaaagta agagtaagaa tatatggcaa
    19441 aaatactgat gtacaaaata ttgaattggt atttaattca gaaaaaatta ttgagttaaa
    19501 tttttaggta taagtcatga ataaagaaaa aataaaaaga aaattaatca caatactgtt
    19561 tgtatgtatt gggatgttat gttttggatt gttagcagga gttaaggctg ataatcgtgt
    19621 tcaaatgaga acgacgatta ataatgaatc gccattgttg ctttctccgt tgtatggcaa
    19681 tgataatggt aacggattat ggtgggggaa cacattgaag ggagcatggg aagctattcc
    19741 tgaagatgta aagccatatg cagcgattga acttcatcct gcaaaagtct gtaaaccaac
    19801 aagttgtatt ccacgagata cgaaagaatt gagagaatgg tatgtcaaga tgttggagga
    19861 agctcaaagt ctaaacattc cagttttctt ggttattatg tcggctggag agcgtaatac
    19921 agttcctcca gagtggttag atgaacaatt ccaaaagtat agtgtgttaa aaggtgtttt
    19981 aaatattgag aattattgga tttacaataa ccagttagct ccgcatagtg ctaaatattt
    20041 ggaagtttgt gccaaatatg gagcgcattt tatctggcat gatcatgaaa aatggttctg
    20101 ggaaactatt atgaatgatc cgacattctt tgaagcgagt caaaaatatc ataaaaattt
    20161 ggtgttggca actaaaaata cgccaataag agatgatgcg ggtacagatt ctatcgttag
    20221 tggattttgg ttgagtggct tatgtgataa ctggggctca tcaacagata catggaaatg
    20281 gtgggaaaaa cattatacaa acacatttga aactggaaga gctagggata tgagatccta
    20341 tgcatcggaa ccagaatcaa tgattgctat ggaaatgatg aatgtatata ctgggggagg
    20401 cacagtttat aattttgaat gtgccgcgta tacatttatg acaaatgatg taccaactcc
    20461 agcatttact aaaggtatta ttcctttctt tagacatgct atacaaaatc cagctccaag
    20521 taaggaagaa gttataaata gaacaaaagc tgtattttgg aatggagaag gtaggattag
    20581 ttcattaaac ggattttatc aaggacttta ttcgaatgat gaaacaatgc ctttatataa
    20641 taatgggaga tatcatattc ttcctgtaat acatgagaaa attgataagg aaaagatttc
    20701 atctatattc cctaatgcaa aaattttgac taaaaatagt gaggaattgt ctagtaaagt
    20761 caactattta aactcgcttt atccaaaact ttatgaagga gatgggtatg ctcagcgtgt
    20821 aggtaattcc tggtatattt ataatagtaa tgctaatatc aataaaaatc agcaagtaat
    20881 gttgcctatg tatactaata atacaaagtc gttatcgtta gatttgacgc cacatactta
    20941 cgctgttgtt aaagaaaatc caaataattt acatatttta ttgaacaatt acaggacaga
    21001 taagacagct atgtgggcat tatcaggaaa ttttgatgca tcaaaaagtt ggaagaaaga
    21061 agaattagag ttagcgaact ggataagcaa aaattattcc atcaatcctg tagataatga
    21121 ctttaggaca acaacactta cattaaaagg gcatactggt cataaacctc agataaatat
    21181 aagtggcgat aaaaatcatt atacttatac agaaaattgg gatgagaata cccatgttta
    21241 taccattacg gttaatcata atggaatggt agagatgtct ataaatactg aagggacagg
    21301 cccagtccct ttcccaacac cagataaatt taatgatggt aatttgaata tagcatatgc
    21361 aaaaccaaca acacaaagtt ctgtagatta caatggagac cctaatagag ctgtggatgg
    21421 taacagaaat ggtaatttta actctggttc ggtaacacac actagggcag ataatccctc
    21481 ttggtgggaa gtcgatttga aaaaaatgga taaagttggg cttgttaaaa tttataatcg
    21541 cacagatgct gagactcaac gtctatctaa ttttgatgtg attctatatg acaataatag
    21601 aaacgaagtt gctaagaaac atgttaataa tttgtcgggt gaatctgtta gtctagattt
    21661 caaagaaaaa ggagcaaggt atattaaagt taaattacta acgagtggag tgcctttgag
    21721 tttagcagaa gtagaggttt ttagagaatc agatggtaag caatctgaag aggatataga
    21781 taaaataaca gaagataaag tagtctctac aaataaggta gctactcaaa gttcaaccaa
    21841 ttatgagggt gtagctgctt tagcagttga tggtaataaa gatggagatt acggacatca
    21901 ttcggtgact catactaagg cagattctaa cgcttggtgg caggttgatc tgggagaaga
    21961 gtttacggtt tctaaagttg atatttataa tagaacagat gccgaacctc agcgtttatc
    22021 taattttgat gttatttttc tatcttcatc aggagaagaa gtttttagaa gacattttga
    22081 taaagtagtt gatggtttgt tatctttaaa agtaccttct gtaggggcta agctagtcaa
    22141 aatagaatta aaatcagcag ctattccgtt aagtttagcg gaagttgaag tctatggttc
    22201 aaagagaact ccgaagaaac tttctaatat tgcattaacc aaagaaactc gacagagttc
    22261 aacggattac aatggttttt ctcgtctagc agttgatgga aataaaaacg gagattatgg
    22321 tcatcattca gtgactcata ccaaaggaga ttctccttca tggtgggaga tagatttagc
    22381 acaaaccgaa gaattagaaa agttaattat ttataataga acagatgctg aaattcagag
    22441 attatcaaat tttgatatta ttatatatga ttcaaataat catgaagttt ttaaacaaca
    22501 tattgacagt ttagaaagca ataatctatc catagactta aaagggctga agggaaaaaa
    22561 ggttagaatt tctttgagaa acgcaggaat tcctttaagt ttagcagagg tagaggttta
    22621 tacttataag taattttaaa aattatcacc caggctaccg taaatataat ggcgatggta
    22681 gtatgaaaga aacagaaaaa taagaggaaa atagtatgat tcaacatcca cgtattggta
    22741 ttcgtccgac tattgatggt cgtcgtcaag gtgtacgcga atcacttgaa gtgcaaacaa
    22801 tgaacatggc taaaagtgtg gcagatttga tttcaagcac attgaaatat ccagatgggg
    22861 aacctgtgga atgcgtgatt tctccatcta ctattggccg tgtaccagag gctgcagctt
    22921 cccatgagtt gtttaaaaaa tcaaatgttt gcgcaacaat tacagttaca ccatgctggt
    22981 gttatggtag tgaaactatg tatatgtctc cagatattcc tcatgctatt tggggattta
    23041 atgggacaga acgcccagga gctgtctatc ttgcagctgt actagcttca catgctcaaa
    23101 aagggattcc agcctttggg atctatggta gagatgttca ggaagctaat gatacagcta
    23161 ttccagaaga tgtcaaagaa aaacttttac gttatgcgcg ggcagctctt gcaactggct
    23221 tgatgagaga cactgcttac ctatcaatgg gtagtgtttc gatggggatt ggtggttcta
    23281 ttgtaaatcc ggatttcttc caagaatact taggaatgcg aaatgaatcg gtagatatga
    23341 cggagttcac acgccgtatg gaccgtggta tttacgaccc tgaagagttc gaacgtgcgc
    23401 tcaaatgggt gaaagaaaac gtaaaagaag gattcgacca taaccgtgaa gaccttgttt
    23461 taagccgtga agaaaaagat agacaatggg aatttgttat taagatgttc atgattggac
    23521 gtgacttaat ggttggtaac ccaagacttg ctgaccttgg ttttgaagaa gaagcagttg
    23581 gtcaccatgc tttagtagct ggtttccaag gtcaacgcca gtggacagac catttcccaa
    23641 atggggactt tatggaaact ttcctcaata ctcagtttga ctggaatggt attcgaaaac
    23701 catttgtatt tgcgacagag aatgattcac taaatggtgt gtctatgctc tttaattatc
    23761 tattaacaaa tactccacaa atctttgctg atgtgcgcac ttattggagt ccagaggctg
    23821 ttaaacgtgt aacgggacat actttagagg gttgtgctgc agctggcttc ttacatctaa
    23881 tcaactctgg ttcttgtaca ttggatggta cagggcaagc tactcgagat ggcaaacctg
    23941 ttatgaaacc attctgggag ttggaagaaa gtgaagtgca ggctatgctt gaaaatacag
    24001 acttcccacc agcaaaccgc gaatacttcc gtggaggagg attcttaact cgtttcttga
    24061 cgaaggggga tatgccagta acaatggtac gtctcaatct tctaaaaggg gttggtccag
    24121 tgctacaaat tgcagaaggt tatacacttg aacttcctga agatgttcac catactttag
    24181 ataatcgtac agatccagga tggccaacta cttggtttgc tccacgtttg acaggaaaag
    24241 gtgctttcaa gtctgtctat gacgtcatga ataattgggg agctaatcac ggagccataa
    24301 catatggaca cattggagca gacttgatta ccttggcttc tatgttgaga attcctgtca
    24361 atatgcataa tgtacccgaa gaagatatct ttagacctaa aaattggtcc ttatttggaa
    24421 cagaagatct agaatcagca gactatcgtg catgtcagtt attgggacca ctacataaat
    24481 aaaacttgtt tatataggag gtgaacttac gtccctccta tccttttaaa aagatttgtt
    24541 aaacaattca caaataattg aaaacgaata caaaaagtaa tataatgatg ttaaatagat
    24601 agcgcggagg cgcaggagga aaattatatg gctacatttt atgttccggc agtcaacctt
    24661 attggaaaag gtgttgtaaa tgaagtgggt ccttatatca aggaacttgg ctataaaaag
    24721 gcacttttgg ttacagataa gtacatcgaa ggcagtgata ttttacctaa ggttttaaaa
    24781 ccactggata cagaaggaat cgaatatgtc atctttagcg atgtagagcc aaaccctact
    24841 tgtaaaaatg tcacagatgg ggtagctgct ttgcaagaac atggctgtga ctttatcatc
    24901 agtcttggcg ggggttctcc acaggatgca gctagttgta tttctatcat ggctacaaat
    24961 ggtggaaaac cacaggatta tgaagggctt cataagtctg ctaaaaaagg cttgccagtt
    25021 gtggctatca atacaacggc aggaacttct gcagaaatca ctattaacta tgtgattact
    25081 gatgaagaac gcaaggttaa gatggtaatg gttgacaaga atagccttgc tcttatctct
    25141 gttaatgacc cggaactcat gctttccaaa cctaaaggcc tgactgctgc tactggtatg
    25201 gatgctctga ctcacgctgt tgaagctttg gtaacacctg gtgcttatga tgtaaccaag
    25261 aaactgtcta ttggtgctat tgagcttatc aaggaatatc ttcctcgtgc tgtagaaaat
    25321 ggacatgata ttgaagcgcg tgaaggtatg gtcaatgcca tcttccttgg tggtatgagc
    25381 tttaataatg ctggtcttgg ttatgttcac tcaatggctc accaactcgg tgcagtatat
    25441 aatttgccac atggtgtttg ctgtgccatg ttgctaccag ttatagaacg tgaaaatgct
    25501 aaacgtgtac cagaagcttt ccgcaatgtt gccaaagcct tgggacttca tgtagaaggt
    25561 aaatcagatc aagaatgtgc cgattatgcg attgttgaga ttgagaagct ttctgagaca
    25621 gtaggtattc ctaagaaact gactgaactt ggtattgaag aaaaagattt cgactttgaa
    25681 tacctttcta agaatgcctt gattgatgcc tgcgcaccag gaaatccatt tatgccaacc
    25741 ttagaagaaa cgattgcctt ttataaagag ttattttagc aagagattgg acgacaatag
    25801 gacaattcac ctctaattat tgacatttca ggaaaaatcg cagtaaaaac ggcacagcct
    25861 tctttaaatg tgctataata ctagaaaaat acttgtggag gttccattat ggcaatattt
    25921 ttcatgattt ttctgattgt ttgtgtgctc ctattggtga tagtcacact gagtacagtt
    25981 tatgtggttc gtcagcagtc ggtggcgatt attgaacgct ttgggaaata ccaaaaggtt
    26041 gccaatagcg gtattcatat tcgcttgcct tttgggattg actcgattgc agcacggatt
    26101 cagttgcgct tgttgcaaag tgatattgtg gttgagacta agaccaagga caatgtgttc
    26161 gttatgatga atgtagcgac tcagtaccgt gtcaacgagc agagcgtgac agatgcttac
    26221 tataaactca tacgtccaga atctcagatt aaatcttata tcgaagatgc tcttcgctct
    26281 tctgttccaa aattaacctt ggatgaattg tttgagaaaa aagatgagat tgcccttgaa
    26341 gttcaacacc aagtagcaga agaaatgacc acttacggct acattatcgt gaaaaccttg
    26401 attaccaagg tcgaaccgga tgcagaagtt aagcaatcca tgaatgaaat caatgcggcg
    26461 caacgtaagc gggtcgcagc acaagaattg gcggaagctg acaagattaa aattgtcact
    26521 gcagctgaag ccgaagcaga aaaagaccgc cttcatggtg tggggattgc ccaacaacgt
    26581 aaggcgattg tggatggatt ggcagagtct atcaccgaac tcaaggaagc caatgttggc
    26641 atgacagaag aacaaatcat gtctatcctc ttgaccaacc agtatttgga taccttgaat
    26701 acctttgcct ctaaaggaaa tcaaaccatc tttttaccaa atactccaaa tggtgtggat
    26761 gatatccgta cacaaatctt gtcagccctt cgcgctgaga agaaataata gactaatact
    26821 cttcgaaaat ctcttcaaac cacgtcagcg tcgtcttgcc gtatagatgt tactgacttc
    26881 gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag tcttatctac
    26941 tacctcaaaa cggtgttttg agcaacctgt ggctagtttc ctagtttgct ctttgatttt
    27001 cattgagtgc aaagagcttg gcaacaggct ctttttgtat tgcgtttatt aagaaaaaca
    27061 aaaaacatcg atatacattt aactaaaaat tattgtatgt tatctccctt aattaggaat
    27121 gataagggaa taactagaaa gatttgtgaa tacaaactat ttctgatata caaaatatac
    27181 agtaataatg aatgatggga gatgggatga aagaatttca atttgagaga aagcagcgtt
    27241 tttctttgag gccatatgca ataggagctt gttcggtctt gctaggaacg agtttatttt
    27301 ttgctggtat gggtgctcag cctgtacagg atacagaaac gagttcagca ctaatttcaa
    27361 gtcattattt ggatgagcag gatttatctg aaaagctgaa atctgagttg caatggtttg
    27421 aattagaaaa caagcttttg aacttatggg agcattaggt tactatgaag gatttgttcc
    27481 ttatgtttca aatcaataca aaaaccaagc tgaagaagaa tacaaaccgc tatctgataa
    27541 atatattttc gaaaaaatct taggaaaaac atatgcagcc ttcaaaaaag atcaaattaa
    27601 tgagcgtgtc gagaaattag gtaagttaaa acctattaca ataaattaca acggaaaatc
    27661 agaagtaatt gatagtaaag aaaaattaca agagcttatg aataaagccg ttaaagacga
    27721 agtggctcaa atatagtaaa atgaaataag aacaggacaa atcgatcagg acagtcaaat
    27781 cgatttctaa aaatgtttta gaagtagagg tgtactattc tagtttcaat atactataaa
    27841 atcaggcaat accacggcta aaaagtttga gtttatcgaa acaccagtgc aaaaactgaa
    27901 aaaagcgatt tataaagctc atctcaaaga ttcagat
//
LOCUS       DAVLUM010000028        26027 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLUM010000028 DAVLUM010000000
VERSION     DAVLUM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.028"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            365..1528
                     /locus_tag="VYN42_001024"
     CDS             365..1528
                     /locus_tag="VYN42_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1462112.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1525..2202
                     /locus_tag="VYN42_001025"
     CDS             1525..2202
                     /locus_tag="VYN42_001025"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1462113.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLNFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2192..3046
                     /locus_tag="VYN42_001026"
     CDS             2192..3046
                     /locus_tag="VYN42_001026"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1462114.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNAAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQDQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3065..4132
                     /locus_tag="VYN42_001027"
     CDS             3065..4132
                     /locus_tag="VYN42_001027"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1462115.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4142..5308
                     /gene="aroC"
                     /locus_tag="VYN42_001028"
     CDS             4142..5308
                     /gene="aroC"
                     /locus_tag="VYN42_001028"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1462116.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDVEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5318..6421
                     /locus_tag="VYN42_001029"
     CDS             5318..6421
                     /locus_tag="VYN42_001029"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1462117.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6432..6770
                     /locus_tag="VYN42_001030"
     CDS             6432..6770
                     /locus_tag="VYN42_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1462118.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKTVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6862..8145
                     /gene="aroA"
                     /locus_tag="VYN42_001031"
     CDS             6862..8145
                     /gene="aroA"
                     /locus_tag="VYN42_001031"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1462119.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKIIVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8138..8614
                     /locus_tag="VYN42_001032"
     CDS             8138..8614
                     /locus_tag="VYN42_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1462120.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDTNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLRADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8611..9459
                     /gene="pheA"
                     /locus_tag="VYN42_001033"
     CDS             8611..9459
                     /gene="pheA"
                     /locus_tag="VYN42_001033"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1462121.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESCPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9456..10730
                     /gene="psr"
                     /locus_tag="VYN42_001034"
     CDS             9456..10730
                     /gene="psr"
                     /locus_tag="VYN42_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1462122.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11009..11854
                     /locus_tag="VYN42_001035"
     CDS             11009..11854
                     /locus_tag="VYN42_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1462123.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGDL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11844..12947
                     /locus_tag="VYN42_001036"
     CDS             11844..12947
                     /locus_tag="VYN42_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1462124.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12949..13935
                     /locus_tag="VYN42_001037"
     CDS             12949..13935
                     /locus_tag="VYN42_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1462125.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13951..15384
                     /locus_tag="VYN42_001038"
     CDS             13951..15384
                     /locus_tag="VYN42_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1462126.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15413..16447
                     /locus_tag="VYN42_001039"
     CDS             15413..16447
                     /locus_tag="VYN42_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1462127.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16647..17384
                     /gene="mecA"
                     /locus_tag="VYN42_001040"
     CDS             16647..17384
                     /gene="mecA"
                     /locus_tag="VYN42_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1462128.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEVKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17535..18821
                     /locus_tag="VYN42_001041"
     CDS             17535..18821
                     /locus_tag="VYN42_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1462129.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGSIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18823..19692
                     /locus_tag="VYN42_001042"
     CDS             18823..19692
                     /locus_tag="VYN42_001042"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1462130.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19768..19845
                     /locus_tag="VYN42_001043"
                     /pseudo
     CDS             19768..19845
                     /locus_tag="VYN42_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            19987..20925
                     /gene="msrB"
                     /locus_tag="VYN42_001044"
     CDS             19987..20925
                     /gene="msrB"
                     /locus_tag="VYN42_001044"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1462131.1"
                     /translation="MAEIYLAGGCFWGLEAYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20983..22707
                     /locus_tag="VYN42_001045"
     CDS             20983..22707
                     /locus_tag="VYN42_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462132.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIREDLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22709..24457
                     /locus_tag="VYN42_001046"
     CDS             22709..24457
                     /locus_tag="VYN42_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462133.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFFLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24759..26018
                     /locus_tag="VYN42_001047"
     CDS             24759..26018
                     /locus_tag="VYN42_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1462134.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPSGVDIQQIYQAVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
BASE COUNT         7651 a         4890 c         5896 g         7590 t
ORIGIN      
        1 tgagtttgta acaaaaggct tctctataaa atcaaatttt ccagatacct actgaagctg
       61 atttatttct ttatctttct tctactacct ttgtcactaa atttgacaga cacatattgc
      121 tgatacaacc tctctaccta taatctcaca gttaacctga ggctagtttc atagtttgct
      181 atttgatttt cgttgataaa aaaaatgctc ctccaagacg gaagagcatt ttttattgtg
      241 attcttacac atttactttc tagttttgca ggaagtctag tataccattt tttaaaagaa
      301 gagtaaaaaa gcaagggtag tttctttttt gagaattgtc taaaagtttg atataatggt
      361 agttatgaat agaataagag tcagcaaaag ggttgaaaag aagcttgcta aggggctagt
      421 tttactagaa gccagtgatc ttgagaatgt caatcttaag gatcaggaag tagaggtgca
      481 gggtcaggaa ggaaactttc ttgggactgc ctacctttct cagcaaaaca agggcttggg
      541 ctggtttgtc agcaaagaca aggtggcctt caatcaagct ttctttgaaa cgttgtttag
      601 aaaagccaaa gaaaagagaa gcgcctacta tcaagatgat ttaacaactg cctttcgtct
      661 ctttaatcaa gagggagatg gctttggggg tctgacagtg gacctttatg gcgactacgc
      721 cgtcttttct tggtataact cttatgttta tcagattcgt cagactatat cagaagcctt
      781 tagacaggtt ttccctgagg ttttaggggc ttatgagaaa atccgcttta agggttttga
      841 ctatgaatct gcccatgttt atggtcaaga agcacctgac tttttcactg ttttagaaaa
      901 tggtgtcctg tatcaagtct ttatgaatga tggcttgatg acaggaattt tcctagacca
      961 gcatgaggtt cgcggtagtt tagttgacgg cttggctatg ggtaaatcct tgctcaatat
     1021 gttttcctac acagcggctt tttcagtagc tgcggccatg ggaggagcta gccagacaac
     1081 ttctgttgat ctagccaaac gttcacgaga attgtctcaa gcgcattttc aggcaaatgg
     1141 gctcagcaca gacgagcatc gttttatagt catggatgtc tttgagtatt tcaaatatgc
     1201 caaacgcaaa gacttgacct acgatgtgat tgtcctagat ccgcctagct ttgctcggaa
     1261 taaaaaacaa actttctctg tggccaagga ttatcacaag ttgatttccc agagtcttga
     1321 gattttaaat ccgggaggga ttatcattgc cagtaccaat gctgccaatg tttcccgcca
     1381 gaaatttaca gaacaaattg ataaaggctt tgcaggaaga agttaccaga ttttaaacaa
     1441 atatggtctt ccagcagatt ttgcctataa taaaaaagat gaaagtagta attacctcaa
     1501 ggtgattagt atgaaggtta gtaaatgaaa ttaatcgttt cagtaatgcc aagaagttta
     1561 gaggaggctc aggctctgga tgccacgagg tacctggatg ccgacatcat tgaatggcgt
     1621 gccgactatc tgcctaaaga agcgattttg caggtagctc cagccatttt tgaaaaattc
     1681 gcaggccgtg agttggtttt cacgctacga actcgctccg aaggtggaga aatcgacctt
     1741 tctccagaag agtatatcca tctaatcaag gaagttgcgc aactctatca accagactat
     1801 attgattttg agtactatag ctacaaggat gtttttgagg aaatgctgaa cttcccaaat
     1861 cttgttttga gttaccataa tttccaagaa acacctgaga acatgatgga aatcttgtca
     1921 gagttgacga tcctaaatcc aaaacttgtt aaggttgcgg tgatggctca cacggagcag
     1981 gatgtcttag acttgatgaa ctatacacga ggctttaaaa ccctcaatcc tgaacaggaa
     2041 tatgtgacca tttctatggg taaggtgggc aaggtctctc gtatcactgc ggatgtgact
     2101 ggttcgagtt ggtcttttgc cagtctggat gaggttagtg cccctgggca gatttctcta
     2161 gctagcatga aaaaaatcag ggagattttg gatgaagctt gatggctata cacgtttagc
     2221 tgcagttgtt gccaatccta ttaagcattc tatttctccc ttcatccaca atagagcctt
     2281 tgaggcgaca gctaccaacg ctgcttacgt ggcttgggag attgaagcga gtgacttggc
     2341 agaaacagtg gccaatattc gtcgctacca gatgtttggc atcaatctgt ccatgcccta
     2401 taaggagcag gtgattcctt atttggatga gctgagcgat gaagcgcgct tgattggtgc
     2461 ggttaatacg gttgtcaatg agaatggcaa tttaattgga tataatacag atggcaaggg
     2521 attttttaag tgcttgcctt cttttacaat ttcaggtaaa aagatgaccc tgctgggtgc
     2581 aggtggtgcg gctaaatcaa tcttggcaca ggctattttg gatggcgtca gtcagatttc
     2641 ggtctttgtt cgttccgttt ctatggaaaa aacaagacct tacctagaca agttacagga
     2701 tcagacaggt tttaaagtgg atttgtgtgc tttagaatat gtttctgaac tgcaagcaag
     2761 gattgccgag tcggatttgc tagttaatgc caccagtgtg ggcatggatg gccaatcctc
     2821 tcctgttcct gaaaacatag tcttaccaga aactctttta gttgcagata tcatatacca
     2881 accctttgaa acaccgtttt tgaaatgggc tagaagtcag ggcaatccag cagtcaatgg
     2941 tctgggaatg ttgctctatc aagctgcaga agcttttcaa ctgtggacag gcaaggaaat
     3001 gccgacagaa gagatttggc agtctttaac agaaaaatac caataaagaa agggagactc
     3061 tcctatgaaa atcagaatcg atattcctca ccatccttat gatattcaga ttgaaaaagg
     3121 ttgtatggcc caggctggtc agtggttgcg agaactctgg caaccgcaaa aggtagtcat
     3181 tgtgacagat aaccatgtag cctctctcta tgcagagaag gtcaagctca gcctagaaga
     3241 tgctggtttt caggtagctg tttttgattt cttagaaggt gaagaaagaa agaatttaac
     3301 tactgttcag aaagtctatg aatttctagt caagcaaggt ctgactcgta gcgatggaat
     3361 cgttgctctt ggtggtggcg ttgttgggga cctggctgga tttgtagcct ctacctatat
     3421 gcggggtatt cactttgttc agattccgac tagtttgaca gctcaggttg attcttctat
     3481 cggtggaaag acaggcgtta acacaccatt tgctaaaaat atggtgggga cctttgccca
     3541 accagatggg gttttgattg atccacttgt tcttgaaacc ctcggaaaaa gagagttgat
     3601 tgaagggatg ggtgaagtta tcaagtatgg cttgattgag gatccagaac tgtgggctct
     3661 cttgacggga ctgaatggtt ctgttgagag tattttggaa catgcagaga ccttgattga
     3721 acattcttgt caggtgaagc gcaagatggt ggttgaagat gagttggaca atggtattcg
     3781 tctttacctc aattttggcc acactattgg ccatgccatc gaagcgactg ccggttatgg
     3841 caaggtcatg catggagagg ctgttgccat gggaatggta cagatttcca agattgctga
     3901 ggaaaaaggc ctcatgccag ctggcattac ccaatctatc acagagatgt gtcagaaatt
     3961 cggcttgcct gttgactatg aaaattggga agttgacaag ctttatcagg ctttgactca
     4021 tgacaagaaa gcgcgtggca acaccttgaa attggtcttg gtgccagagc ttggttcagc
     4081 gaccattcat ccagtttctc tggaagagat gaaagactac ttggtaaaat aaggagagtg
     4141 tatgagatat ttaactgcag gagaatcaca cggcccccgt ctaacagcta ttattgaggg
     4201 aattccagct ggacttccat tgacagctga ggatatcaat gaggacctta gacgccgtca
     4261 gggtggctac ggtcgtggtg gtcgtatgaa gattgagagt gaccaggttg tctttacttc
     4321 gggcgttcgc cacgggaaga cgacaggggc gcctattact atggatgtca tcaataagga
     4381 ccaccagaaa tggctggaca tcatgtctgc ggaggacatt gaagaccgcc ttaaaagcaa
     4441 gcggaaaatt actcatcctc gcccaggtca tgccgatttg gttgggggga ttaagtaccg
     4501 ttttgatgat ttgcgaaatt ctttggagcg ttcatcagct cgtgaaacca ccatgcgggt
     4561 ggcagttggt gcagtagcca aacgcctctt ggctgagctg gatgtggaga ttgccaacca
     4621 tgtcgtggtc tttggtggca aggaaatcga tgttcctgaa aatctgacag tcgctgaaat
     4681 taagcaaaga gctgcccagt ctgaagtttc tattgttaac caagaacgag aacaggaaat
     4741 caaggactat attgaccaaa tcaaacgtga tggtgatacc atcggtgggg ttgtggagac
     4801 agtcgtcgga ggcgttccag ttggtcttgg ttcctatgtc caatgggata gaaaattgga
     4861 tgcaagattg gctcaagctg ttgtctctat caatgccttt aaaggggtgg aatttggtct
     4921 tggctttgag gctggttatc gtaaaggcag ccaagttatg gatgaaattc tctggtctaa
     4981 agaagacggt tatactcgcc gtaccaataa tctaggtggt tttgaaggtg gtatgactaa
     5041 tgggcaaccc atcgttgttc gtggggtcat gaaacccatt cctactcttt ataaacctct
     5101 tatgagtgtg gatatcgaaa cccacgaacc ttacaaggca accgtggaga gaagtgatcc
     5161 gactgctctt ccagctgcag gaatggtcat ggaagcagtt gtagcaacgg ttctggcgca
     5221 agaaatcctc gaaaaattct catcagataa tcttgaggaa ctaaaagaag cggtagccaa
     5281 acaccgagac tatacaaaga actattaagg agttcctatg gcaaaaacaa tctatatcgc
     5341 aggtcttggg ttgattggag cctctatggc acttggtatc aaacgcgatc atccagatta
     5401 tgaaatttta ggttataatc gtagtcaagc ttcgagagat atcgccttga aagaaggcat
     5461 gattgaccgt gcaacggatg attttgctag ttttgctcct ttggcagatg tcattatcct
     5521 cagcttgcca atcaaacaaa ctattgcttt cattaaggag ttggccaatt tggatttgcg
     5581 agaaggcgtt attatttcag atgctggttc gaccaagtca accattgtgg atgcggcgga
     5641 gcagtatttg gctggcaagt ctgttcgctt tgtcggggcc catcccatgg ctggtagtca
     5701 caagacaggg gctgcttcgg cagatgtcaa tctttttgaa aatgcctatt atatctttac
     5761 accttcaagc ctgacaagtc aggacacgct taaggaaatg aaggatctac tttcaggtct
     5821 tcatgctcgt tttatcgaga ttgatgccaa ggagcatgat cgtgtcactt ctcagattag
     5881 ccattttcct catattttgg cttctagtct catggagcag actgcggtct atgctcaaga
     5941 gcatgagatg gcaaggcgct ttgcggcagg tggttttcga gatatgaccc gaattgcgga
     6001 aagcgagcca ggaatgtgga cctccattct cttgtccaat agcgagacca ttctggatag
     6061 aattgaggat ttcaaggaac gtttggaagt gattggtcag gccattagta agggagatga
     6121 agagcaaatt tggaactttt ttaaccaagc gcgtgaacaa cgccagacca tggaaatcca
     6181 taagcgtggt ggtgtggata gctcttacga cctctatgtt gacgttcctg atgaagaaga
     6241 tgtcatcctg cggattttgg aactgctacg tggaacttcc ttggttaaca tccacatcaa
     6301 cgaggaaaat cgtgaggata ttcacggaat cctacaaatt tcatttaaaa atgctcaaga
     6361 cttggaaaga gctgagcatc tcataacaga aaataccgac tatacagtcg tcatcaaata
     6421 aggagaagaa catgtcaaat atttacgata gtgcaaacga actcagtcgc ggtctacgcg
     6481 gattaccaga atacaagact gttaaagcag ctaaagatgc gattgcagca gatgctgagg
     6541 caagcaaaat ctttacagaa tatcttgcct ttcaagagga aattcaaaaa ctagcacaga
     6601 caggtcaaat gccagatgcg tccttccaag ctaagatgga aggctttggt aaacagattc
     6661 aaggaaatag cctcttgtca gaattcttta ccaagcaaca acaattggcc atttaccttt
     6721 ctgacattga aaaaattgtt tttgaaccag tttcagaatt gctgaaataa gaaaagaacg
     6781 atcctaaagt caggaatttt taaggaattt ctggcttttt atgataaaat aggtaaaagt
     6841 attgcaagta tgaggtccag tatgaaacta aaaacaaaca ttcgccattt acatggtagt
     6901 atccgcgtcc caggtgacaa gtctatcagc caccgttcca ttatctttgg aagtttggct
     6961 gagggtgaga ccaaggttta tgatattctg cgaggtgaag acgtcctttc gaccatgcag
     7021 gtttttcgtg accttggtgt tgaaattgag gataaagatg gggttattac cattcaaggt
     7081 gtaggcatgg ctggcttaaa agcgccacaa aatgccctta atatgggaaa ttctggcacc
     7141 tcgattcgcc tgatttcagg tgtccttgct ggtgcagatt tcgaagtaga gatgtttgga
     7201 gatgatagtc tttccaaacg tcctatggac cgtgtgaccc ttccactgaa aaaaatgggc
     7261 gtcagcattt caggacaaac tgaacgagac ttgcctcccc ttcgcttaaa agggacgaaa
     7321 aacctaagac ctattcatta tgagttgcca attgcctctg cccaagtcaa gtcagccttg
     7381 atgtttgcag ccttacaagc taagggggag tcagttatta tcgaaaaaga gtgcactcgt
     7441 aatcatactg aagatatgtt gaaacaattt ggtggtcatt taagtgtgga cggtaagaaa
     7501 atcatagtcc aagggccaca aaaattgaca ggacagaagg tggtcgtacc aggagatatt
     7561 tccagtgcag ccttttggtt agtcgcaggt ttgattgttc caaattctcg tctagtgctg
     7621 cagaatgtgg ggatcaacga aactcgcacc ggtattattg atgtcattcg tgccatgggt
     7681 ggaaaattgg aaataactga aatcgatcca gtcgctaaat ctgcaacctt gattgttgag
     7741 tcttctgact tgaaaggaac agagatttgt ggcgctttga ttccacgttt gattgatgaa
     7801 ttgcctatta ttgccctact tgcgacccaa gcccaaggtg taacagttat caaggatgct
     7861 gaggagctca aggtcaagga aacagaccgt attcaggttg tggcagacgc cttaaatagt
     7921 atgggagcag atattactcc tacggcagat gggatgatta tcaaaggaaa atcagctctt
     7981 cacggtgcta gagtcaatac gtttggtgac caccgtatcg gcatgatgac agctatcgca
     8041 gccctcttgg ttgcagatgg agaggtggag cttgaccgtg cagaagccat caataccagc
     8101 tatcctagtt tctttgatga tttggagagc ttgattcatg gctaaggtgt tattagggtt
     8161 tatgggggct ggaaaatcga ctattgcaag aggcttggac actaattacc ttgatatgga
     8221 tgctctgatt gagaagcgcc taggtatgtc cattgcgaat tttttcgctg aaaagggaga
     8281 agcagccttt cgtcaggtag aatcagaagt cctagctgat ttactacaaa cagaccaagt
     8341 cgtgtcaact ggaggaggag tggttatttc tcagagaaat cgtgacttac tcaagactaa
     8401 tacagataac atctacctga gagcagattt tgaaaccctc taccaacgta tcgcagctga
     8461 taaggacaat cagcgaccgc tttttctaaa taatagcaag gaagaactag tagctatttt
     8521 ccaagaaaga caggcttggt atgaggaagt ggctagtcgg gttttggatg tgaccaagct
     8581 aagcccagag gaaattatag aggaactaag atgaaaattg cttatctagg tcccaaggga
     8641 tcattttcac accacgttgt gcagacagct tttcctcatg aggaattgca ggcttttgcc
     8701 aacattacag atgtcatcaa ggcttatgag caaggattag tgaactattc tgtggtgcca
     8761 gttgaaaatt ctattgaggg tagtgttcat gaaaccttgg actatctttt tcatcaggct
     8821 cacatccaag cagtagcaga aatcgttcag cctattcatc agcagttgat ggtggttcca
     8881 ggccatacta agattgaaaa gattttttca catccacagg ccttggctca aggaaagaaa
     8941 ttcatcgatg aacaatatcc agaggctcaa atcgaggtaa cagctagtac agcttatgcg
     9001 gcccgtttta tttccgaaca tccagaccag ccctttgcag cagttgcacc tagaagttct
     9061 gctgaagaat atggattgga actgattgcc gaggatattc aggaaatgga agccaatttc
     9121 acacgtttct gggttctagg agctgaaaag cctagtattc ccttgcaagc acaaactgaa
     9181 aagatgagtt tggccttgac attacctgac aaccttccag gtgcacttta taaggccctg
     9241 tcgacctttg cttggcgagg aattgacttg acaaaaattg aaagttgtcc actcaagaca
     9301 gcactgggtg aatacttttt cattatcgat gtggattata ccgataagga cttggtccac
     9361 tttgcccaaa aagaattaga agcgattgga atccagtata aaattctggg tgcctatcct
     9421 atttatccaa tatcagacca tggaaaggag agaagatgag taaagaaaat cccttaagtc
     9481 atcatgagca gttgcgttat gattatttgc taaaaaatat tcactatctc aatgagagag
     9541 aaaaaaatga gtttgcctat ttgcaagaaa agctaactct tgctagggga aatagtagct
     9601 ctagcttgga acaagaaaga gaagagcagg ttgacttacc aagctatgcg aaccggagtc
     9661 gctcacaatc caaatcacaa gcactctctt tccctccaaa aaagaaaaga cggaagctcc
     9721 gtcttaaacg aatttttatg gtgatttttt cacttttggt ctgtgtggct ttggccatgg
     9781 tattcatgtt tttgcgtggt taccaagatg ctagcgcaaa gaaaactgct gatgcccggg
     9841 cagctcaagt agaagtcttt aatggtcagg acactagaga tggagttaat attttaatca
     9901 tgggtactga tggtcgaatc ggccagaaca gtgttgagac acgaactgac tctattatgg
     9961 tattaaatgt cgggggctca gataagaaaa tgaagctagt cagtttcatg cgtgataatt
    10021 tggtctatat agatggttat agtcaagtga ttaatggtag aaaacagaca gataacaagt
    10081 taaacgtagc ctacgagtta ggagaacaag aggggcaaaa aggggcagaa atggttcgcc
    10141 aagtcttgaa agataatttt gacttggaca ttaagtacta cgccttggtt gatttccagg
    10201 cctttgccac agcgattgac acgcttttcc ctgatggggt gacgattgat gctcaatttt
    10261 caacattgaa tgggcgtccc ctaacagaag ctacagtcgg agatgattta tacgctaccg
    10321 agactgagtc tccaacccaa accattaaag tcggaaaaca gcagatgaat ggctcgaccc
    10381 tgctcaatta tgctcgtttc cgtgatgatg atgaggcaga ttacggccgt acaaaaagac
    10441 agcaacaagt tttaacagca attttagagc aaattaaaga tcccactaaa cttttcactg
    10501 gttctgaagc tcttggaaag gtttttgcta tgacctcaac caacgtaccc tatactttcc
    10561 tcctaacaaa cggtttatct gttttggatg gagcaaaaaa tggtattgaa aaattgacga
    10621 ttccagaact gggtgactgg gtagatgcct atgatgttta tgggggcttg ggcctgctgg
    10681 ttgatcaaaa caaatatcaa accaagctcg ctcaaatggg cttaagataa gataatactc
    10741 aatgaaaatc aaagtgcaaa ctaggaagct agccgcaggc tgctaaaaac acagttttga
    10801 ggttgtagat aagactgacg aagtcagtta cctataccta cggcaaggtg aagctgacgt
    10861 ggtttgaaga gattttcgaa gagtataaga cagaaaaatc aaagtttgat agctatttgg
    10921 atagcagtca ggctttgatt ttttacagtc tgcaatagat tttcacccct tgtttgtggt
    10981 ataatgaaac gatacgatag aaagaataat gaacaatatg actgatttaa aagcaattca
    11041 ggctcgtagt ctggagatgg ctgaatattt tgtggccttt tgtaaagaac atgatttgct
    11101 ctgttatctc tgtggcggag gcgctattgg tgcccttcga aacaagggat ttattccttg
    11161 ggacgacgac ctagactttt ttatgcctcg taaagattat gagaaattag cagaattatg
    11221 gcctcgttat gcagatgaac gttatttctt gtcaaagagt cacaaggatt ttgttgatcg
    11281 taatcttttt attaccattc gtgacaagaa aaccacctgt atcaagcctt atcagcagga
    11341 tttggatttg ccacatggtc tggccttgga tgttttgcct ttggattatt atccgaaaaa
    11401 tccagctgag cggaaaaaac aggttcgttg ggccttgatt tattcactct tttgtgcgca
    11461 aactattcca gaaaagcatg gtgatctcat gaaatgggga agtcgcattt tactgggttt
    11521 gactccaaaa tctctccgtt atcgcatctg gaaaaaagct gagaaagaaa tgactaagta
    11581 tgatttggct gattgtgatg gcattacaga attatgctca ggtcctggct acatgagaaa
    11641 caagtaccca atcacatctt ttgaagacaa tcttttcttg ccatttgaag gaacagagat
    11701 gcctattcca atcggctatg atgtctatct cagaactgct tttggggatt atatgacgcc
    11761 tccaccagca gacaagcagg taccgcatca tgatgctgtc atcgctgata tggataagtc
    11821 ttatacagaa tacaagggag aatatggtgg ctaagaaaaa aatcttattt tttatgtggt
    11881 ctttttctct tggaggtggt gcagagaaga ttctatcaac cattgtttca aatctggatc
    11941 cagaaaagta tgatattgat attcttgaaa tggagcactt tgacaaggga tatgaatctg
    12001 ttccaaagca tgtacgcatt ttaaaatccc ttcaagatta tcgccaaacc agatggttac
    12061 gagctttttt gtggagaatg agaatttatt ttccaagact gactcgtcgt ttgcttgtaa
    12121 aagatgatta tgatgttgaa gtttctttta ccattatgaa tccaccactg ttgttctcta
    12181 aaagaagaga agtcaagaag atatcttgga ttcatggaag tattgaagaa cttcttaagg
    12241 atagctctaa aagagaatca catagaagcc agttggatgc tgcgaataca attgtaggga
    12301 tttcaaaaaa gaccagcaat tctatcaagg aagtttatcc agattatact tctaaattac
    12361 agacaatcta caatggatat gattttcaga ctattctaga aaaatctcaa gagaagatcg
    12421 atatcgagat tgctcctcaa agtatctgta ctatcggacg gattgaggaa aataagggtt
    12481 ctgaccgtgt agtggaagtg atacgattat tacaccaaga gggaaaaaac tatcatctct
    12541 attttatcgg ggctggtgat atggaagagg aactgaaaaa acgagtcaaa gagtatggga
    12601 ttgaggacta tgtacatttc cttggttatc aaaaaaatcc ttatcagtat ctatctcaga
    12661 cgaaagttct tttgtctatg tctaaacaag aaggttttcc tggagtgtat gtggaggcct
    12721 tgagtctggg actccctttt atctctacgg acgttggagg ggctgaggaa ttatcccaag
    12781 aaggacgatt tggacaaatc attgagagca atcaagaggc agctcaggcg attactaatt
    12841 acatgacttc tgcctcaaac tttgatgtcg atgaggctag ccaattcatt caacaattta
    12901 caattacaaa acaaatcgaa caagtagaaa aactattaga ggagtagcat ggaaactgca
    12961 ttaattagtg tgattgtgcc agtctataat gtggcgcagt acctagaaaa atcgatagct
    13021 tccattcaga agcagaccta tcaaaatctg gaaattattc ttgttgatga tggtgcaaca
    13081 gatgaaagtg gtcgcttgtg tgattcaatc gctgaacaag atgacagggt gtcagtgctt
    13141 cataaaaaga acgaaggatt gtcgcaagca cgaaatgatg ggatgaagca ggctcacggg
    13201 gattatctga tttttattga ctcagatgat tatatccatc cagaaatgat tcagagctta
    13261 tatgagcaat tagttcaaga agatgcggat gtttcgagct gtggtgtcat gaatgtctat
    13321 gctaatgatg aaagcccaca gtcagccaat caggatgact attttgtctg tgattctcaa
    13381 acatttctaa aggaatacct cataggtgaa aaaatacctg ggacgatttg caataagcta
    13441 atcaagagac agattgcaac tgccctatcc tttcctaagg ggttgattta cgaagatgcc
    13501 tattaccatt ttgatttaat caagttggcc aagaagtatg tggttaatac taaaccctat
    13561 tattactatt tccatagagg ggatagtatt acgaccaaac cctatgcaga gaaggattta
    13621 gcctatattg atatctacca aaagttttat aatgaagttg tgaaaaacta tcctgacttg
    13681 aaagaggtcg cttttttcag attggcctat gcccacttct ttattctgga taagatgttg
    13741 ctagatgatc agtataaaca gtttgaagcc tattctcaga ttcatcgttt tttaaaaggc
    13801 catgcctttg ctatttctag gaatccaatt ttccgtaagg ggagaagaat tagtgctttg
    13861 gccctattca taaatatttc cttataccga ttcttattac tgaaaaatat tgaaaaatct
    13921 aaaaaattac attagaacgg gggtgaccaa gtgattgatg ggaaacgatt attatttagt
    13981 ttgaccatag tcagttatgc cttgacgcta gtaagtggaa ttgtgtatct gtttaataat
    14041 aataatgtta gcttactttc tactttattg ttcttgttgg ttagtagctt aattgcttgt
    14101 tggaatgata tcaagtatta cttaatccat tttattttct atttaaccat ttttgtattt
    14161 ctggtatcaa gaccgaccat tgattatttt agggatggtg ctttggatac ctatcatcca
    14221 atagcctatc gttttgcctt tatagttgtc atggtttcga ttctgggctt gaccacagga
    14281 ggcattctgg ctcgttactt catagctagg aagaaaataa aagtagcaaa tataggaaat
    14341 tctctaaaag aggtttatat caagcggtta cgctttgtat cactaggagt ttttcttcta
    14401 acctatcctt tctatttcat tcggttattt gaacggctct tgtatcgttt gcagacttcc
    14461 tactatgcct actatgcaaa ttttgaaagt aaactgcctt attttaccta cattttgtct
    14521 acctttacgg tctatgcaat gtgtatgtat ctagcaacca agccaaagaa attgcaggcc
    14581 acagcagtgc ttgtctcctt tattgcagct aatactattc atttggcaat tgggacacga
    14641 aatcccttta ttttaagtat tttatttgct tttgtttatt actttatgcg ggagcaagct
    14701 gaaaaaggaa aatggattgg gtttaaagaa aagttagcga tttttgtagg ttctcctatt
    14761 ctcatgttag cgatgggagt actcaattat gtacgggata atgtccaagt ttctcataca
    14821 ggtttctggg atatcttact tgactttatc tataaacaag ggactagttt tggtgttctg
    14881 gctcgaggtt ttctatttaa cagtagcctc ccttaccgag atttccgtaa ttttactttt
    14941 ggtcctgttc ttgattattt tgcaaggggg agtttgggag ccattttcgg aggaaaagcc
    15001 tttgaacata caaccaatag tgtggaacta gctattgata gtaatagtta tgcccacaat
    15061 ctatcctatc ttgtcttgaa caaggaatac ttgaaagggc atggtatcgg aagtagttat
    15121 atcatggagt tgtataccga ctatggtatg attggagtct ttctgcttag tttcttactc
    15181 ggcgtattat ttatagccat gctgcaagta gcctatcgct caaggacaat cctatttgct
    15241 ttatccctac tcatcttgaa taatctattc tttatgccaa gaagcagctt ttcagaaagt
    15301 ttcttcaatt tatttacaat gcaattctgg ggaattgttc ttgtgattat atttgtagca
    15361 aaaatgctta caaaggaaaa ctagtatcta ctaaacaaag gagaaaaaaa tcatgtttga
    15421 acattattca gtagctgatt tgtttgcaaa tctttataaa aaacgaaaag caaatatttt
    15481 agctctcatc gctttatttg ctctcattgc tgtaccattt acaattaaag cagttaggaa
    15541 taaaaacact gtcaaagata caacaagtta ttcaacttat cttatctata aaatcactcc
    15601 tccagaagat tcggccaaaa cgattttgaa tcatcaaatt ggtggttata gtgattttta
    15661 tgggaaattg attgatggta atttgaatgg agcttatctt ttcaatgatg tagaacccag
    15721 tgagttgaaa aaaattgcca gtgaattaga cacgacggaa acaaccttga aaaattcaac
    15781 gaatgactat tggtggaaaa aattgaccgt ctactatatg attgacgatg caggggttgg
    15841 tgtgaaaatt ttgacatcaa gtaaagatgc caatgacttg ttagagaaaa aaattgatgg
    15901 gttgattgag aaatttaaac atgcttatgc aaatgtgaaa attgaaaaac tggaaaccat
    15961 caactctaaa gaattgaacg caaatggtga aacagcgctt ggcttaaatg tgaaaaatct
    16021 gattcttcgt ttagttgtta ttggagtggt ttgtgtgatt ttggttgtga tgggaaatgt
    16081 gttagtttat ctctttaatc caacaatcaa tagagtaggt gatttttctc agtatcaaat
    16141 tgattttgta acagagatta caacaattgc taacctagca gatgttttgt catacaaaaa
    16201 tactggacag gaattgacca tcgttagctc aaataaagct atcttagata aattgaaaca
    16261 gagtcaagaa gctttaaaag gaatgcattt tgtagattta caggatgtat catctctttt
    16321 ggaaagagat acagtccttc ttgttgaaga gtacggagtg actcgttata agaaatttga
    16381 gcaaagtctt caaattctca gaaacttaaa tcgttctatc ctcggtgtag caacctttaa
    16441 attataagta ttctgatgta taaggtcttc aaagtcggct cttagccgat tttgaaggct
    16501 ttttctatct gtctgcagaa attttctttt ggagtctcct atagaaagac cctagggaaa
    16561 atctatccgt atagaggagc cttcttttga taaaatcgta aaaatctagt ataatagata
    16621 gaactgaaag tatgaggtta ctagcaatga aaatgaaaca aattagtgat acaactttaa
    16681 aaatcacgat atctttagag gatttgatgg atcgtggaat ggagattgct gactttctcg
    16741 ttcctcaaga aaaaacagaa gagttctttt atgctatctt ggatgagcta gagatgcctg
    16801 atagctttct ggatacaggc atgttgagct tccgtgtgac tccaaaacct gataaggtag
    16861 atgtctttgt gaccaagtca aagattgacc aaaatctaga ttttgaagac ttatcggatt
    16921 tgccagatat ggaagaattg gctcaaatgt ctccagatga atttatcaaa accctggaaa
    16981 aaagcatcgc agacaaaacc aaggatgata tcgaagccat tcaatctctt gagcaagttg
    17041 aagtcaagga agaagagcaa gagcaggctg aacaagaagc tgagagtaag aaagaacctt
    17101 acatctacta catcctttct tttgctaagt tggctgactt ggtagctttt gccaagacag
    17161 tgacttttga aatggaaact tctgaactct acaaaatgaa cgagcgctat tatttgacca
    17221 ttttagtgga tattgaaaat catccaagcc catatccagc ttggctgttg gcccgtatgc
    17281 gcgagtttgc agacgatagt gatatcagtc gctcagtctt acaagagtat ggtcaagtct
    17341 tgatgagtca cgatgcagtg ctcaatctgc aaaaaatcgg ctaatccttt ctggaaagct
    17401 attttcagat tttaagaaga gcgaatcgtc tgattcgttt tttcttttta tactgaaata
    17461 gtgatttact ataataggaa ttttcacaaa attctgttat aatggctata ttagaaaatt
    17521 tcgaggagat aaagatgaca gttaaaattg ctttactagg atttggtacc gttgcaagtg
    17581 gtgtgccttt cctcctaaag gaaaatggag gaaaaatcaa tcaatcagca cattcagata
    17641 tcaaagttgc taaggtattg gtcaaggatg aagatgaaaa aaatcgcttg cttgcagcag
    17701 ggaatgactt taactttgta accaatgtgg atgatatttt atcagaccag gatattacta
    17761 tcgtagtgga attgatgggg cgtattgagc ctgctaaaac ctttatcact cgtgccttgg
    17821 aagctggaaa acacgttgtt actgctaaca aggacctttt agctgtccat ggcgcagaat
    17881 tgctagaaat cgctcaagct aacaaggtag cactttacta cgaagcagca gttgctggtg
    17941 ggattccaat tcttcgtact ttagcaaatt ccttggcttc tgataaaatt acgcgcgtgc
    18001 ttggagtagt caacggaact tccaacttca tggtgaccaa gatggtggaa gaaggctggt
    18061 cttacgatga tgctcttgcg gaagcacaac gtctaggatt tgcagaaagc gatccgacga
    18121 atgacgtaga tgggattgat gcagcctaca agatggttat tttgagccaa tttgcctttg
    18181 gcatgaagat tgcctttgat gatgtagccc acaagggaat ccgcaatatc acaccagaag
    18241 acgtagctgt agctcaagag cttggttacg tagtgaaatt ggttggttct attgaggaaa
    18301 cttcttcagg tattgctgca gaagtgactc caaccttcct acctaaagcg cacccacttg
    18361 ctagtgtgaa tggcgtaatg aacgctgtct ttgtagaatc tatcggtatt ggtgagtcta
    18421 tgtactacgg accaggtgcg ggtcaaaaac caactgcaac aagtgttgta gctgatattg
    18481 tccgtatcgt tcgtcgtttg aatgatggta gcattggcaa agacttcaac gaatatagcc
    18541 gtgacttggt cttggcaaat cctgaagatg tcaaagcaaa ctactatttc tcaatcttgg
    18601 ctctagactc aaaaggtcag gtcttgaagt tggctgaaat cttcaatgct caagatattt
    18661 cctttaagca aatccttcaa gatggcaaag agggtgacaa ggcgcgtgtc gttatcatca
    18721 cacacaagat taataaagcc cagcttgaaa atgtctcagc tgaattgaag aaggtttcag
    18781 aattcgacct cttgaatacc ttcaaggtgc taggagaata agatgaagat tattgtacct
    18841 gcaaccagtg ccaatatcgg gccaggtttt gactcggtcg gtgtagctgt aaccaagtat
    18901 cttcaaattg aggtctgcga agaacgagat gagtggctga ttgaacacca gattggcaaa
    18961 tggattccac atgacgagcg taatctcttg cttaaaatcg ctttgcaaat tgtaccagac
    19021 ttgcaaccaa gacgcttgaa aatgaccagt gatgtccctt tggcgcgcgg tttgggttct
    19081 tccagctcgg ttatcgttgc tgggattgaa ctagccaacc aactgggtca actcaactta
    19141 tcagaccatg aaaaattgca gttagcgacc aagattgaag ggcatcctga caatgtggct
    19201 ccagccattt atggtaatct cgttattgca agttctgttg aagggcaagt ctctgctatc
    19261 gtagcagact ttccagagtg tgattttcta gcttacattc caaactatga attacgtact
    19321 cgcgacagcc gtagtgtctt gcctaaaaaa ttgtcttata aggaagctgt tgctgcaagt
    19381 tctatcgcca atgtagcggt tgctgccttg ttggcaggag acatggtgac cgctgggcaa
    19441 gcaatcgagg gagacctctt ccatgagcgc tatcgtcagg acttggtaag agaatttgcg
    19501 atgattaagc aagtgaccaa agaaaatggg gcctatgcaa cctacctttc tggtgctggg
    19561 ccgacagtta tggttctggc ttctcatgac aagatgccaa caattaaggc agaattggaa
    19621 aagcaacctt tcaaaggaaa actgcatgac ttgagagttg atacccaagg tgtccgtgta
    19681 gaagcaaaat aaagaataga agataggatg gggaaactct tgaccagagg gtttcatatc
    19741 ctttttgtga aaagaagttt atactcaatg aaaatcaaag agcaaactag gaagctagcc
    19801 gcaggctgct caaaacagtg ttttgaggtt gtggatagaa ctgacgaagt cagctcaaga
    19861 cactgttttg aggttgcaga tagaactgac gaagtcagta acatacctac ggtaaggtga
    19921 cgctgacgtg gtttgaagag attttcgaag agtattagtt aaaaacgtga taaaggagaa
    19981 ataaaaatgg cagaaattta tctagcaggt ggttgttttt ggggcctaga ggcatatttt
    20041 tcacgcattt ctggagtgct agaaaccagt gttggctacg ctaatggtca agtcgaaacg
    20101 accaattacc agttgctcaa ggaaacagac catgcagaaa cggtccaagt gatttacgat
    20161 gagaaggaag tgtcactcag agagatttta ctttattatt tccgagttat cgatcctcta
    20221 tctatcaatc aacaagggaa tgaccgtggt cgccaatatc gaactgggat ttattatcag
    20281 gatgaagcag atttgccagc tatctacaca gtggtgcagg agcaggaacg catgctgggt
    20341 cgaaagattg cagtagaagt ggagcaatta cgccactaca ttctggctga agactaccac
    20401 caagattatc tcaggaagaa tccttcaggt tactgtcata tcgatgtgac cgatgctgat
    20461 aagccattga ttgatgcagc aaactatgaa aagcctagtc aagaggtgtt gaaggccagt
    20521 ctatctgaag agtcttatcg tgtcacacaa gaagctgcta cagaggctcc atttaccaat
    20581 gcctatgacc aaacctttga agaggggatt tatgtagata ttacgacagg tgagccactc
    20641 ttttttgcca aggataagtt tgcttcaggt tgtggttggc caagttttag ccgtccgatt
    20701 tccaaagagt tgattcatta ttacaaggat ctgagccatg gaatggagcg aattgaagtt
    20761 cgttctcgtt caggcagtgc tcacttgggt catgttttca cagatggacc gcgggagtta
    20821 ggcggcctcc gttactgtat caattctgct tctttacgct ttgtggccaa ggatgagatg
    20881 gaaaaagcag gatatggcta tctattgcct tacttaaaca aataaaacag agagtggggc
    20941 ttcccacttt cttcatttct agaatatgaa tagaagggat ttatgaaaca cctattatct
    21001 tacttcaaac cctacatcaa ggaatcaatt ttagccccct tgttcaagct gttagaagct
    21061 gtttttgagc tcttggttcc catggtgatt gctgggattg ttgaccaatc tttacctcag
    21121 ggagatcaag gtcatctctg gatgcagatt ggcctgctcc ttatctttgc agtaattggc
    21181 gttttagtgg ccttgatagc tcaattttac tcagcaaagg cagcagtagg ttttgctaag
    21241 gaattgacaa acgatcttta tcgtcatatt ctttccttgc caaaggacag cagagaccgt
    21301 ctgacaactt ctagtttggt tactcgcttg acttcggata cctaccagat tcagactggt
    21361 atcaatcaat tcctgcgtct ctttttacga gcgcccatta tcgtttttgg tgccattttt
    21421 atggcttatc gaatctcagc tgagttgact ttctggttct tagtcatggt tgccattttg
    21481 accattgtca ttgtagggtt atctcgattg gtcaatcctc tctacagtag tctcagaaag
    21541 aaaacggacc aactggttca ggaaacgcgc cagcaattgc aagggatgcg ggttattcgt
    21601 gcttttggtc aagaaaaacg agagttacag atttttcaaa cccttaacca agtttatgct
    21661 agattacaag aaaagacagg tttcttgtct agtttattaa cacctctgac ctatctgatt
    21721 gtcaatggaa ctcttctcgt tattatctgg caaggctata tttcaattca aggaggagta
    21781 ctcagtcaag gtgctctcat tgctcttatc aattacctct tacagatttt ggtggaattg
    21841 gtcaagctag ccatgctgat caattccctc aaccagtcct atatctcagc caagagaatc
    21901 gaggaggtct ttgcggaatc tcccgaaaac atccattcag aattagaaca aaagcaagtt
    21961 accagtggtc gggttttaca agtccaagaa ttgactttta cctatcctga tgcggcccag
    22021 ccttctctga gagacatttc ctttgatatg actcaaggac aaatccttgg tatcattggg
    22081 gggactggtt ctggtaaatc aagcttggtg caactcttac ttggacttta tccagtagac
    22141 aaggggaaca ttgaccttta tcaaaatgga cgtagtcctc ttaatttgga gcagtggcgg
    22201 tcttggattg cctatgtacc tcaaaaggtc gaactcttta agggaactat tcgttccaac
    22261 ttgactttag gtttaaatca agaagtgact gatcaagaac tctggcaagc cttggagatt
    22321 gcgcaagcta aggattttgt cagtgataag gaaggactct tggatgctct agttgaagca
    22381 ggagggcgaa atttctcagg tggacaaaaa caaaggctgt ctatcgcacg agcagtcttg
    22441 cgccaggctc cgtttctcat cctagatgat gcgacctcgg cactggatac cattaccgag
    22501 tccaagctct tgaaagctat ccgcgaagat ctgccaaata tgagcttaat cttgatttct
    22561 caacggactt cgacactcca gatggcggac cagattctcc tcttggaaaa aggtgagttg
    22621 ctagctgttg gcaagcacga tgacttgatg aaatccagcc aagtctatcg tgaaatcaat
    22681 gcatcccaac atggaaagga ggactagaat gaaacgacaa actgtaaacc agacgctcaa
    22741 acgtttagcc gtagatttag caagccatcc tttcttcctt ttcctagcct ttctaggaac
    22801 tattgcccaa gttggcttat caatttacct acctattctg attgggcagg tcattgacca
    22861 agtcctagtg gctggttcat caccagtttt ttggcagatt tttctccaga tgctcttggt
    22921 ggtaatagga aatactctgg tacaatgggc caatcctctc ctctataatc gtctaatctt
    22981 ctcttatacc agagatttac gggagcgaat catccataag ctccatcgtt taccgattgc
    23041 ctttgtagat aggcaaggta gtggagagat ggttagtcgt gtaaccacgg acatcgaaca
    23101 gttggcagct ggcttgacca tgatttttaa ccaatttttc attggtgttt tgatgatttt
    23161 ggttagtatt ctagccatgc tccaaattca tctcctcatg actctcttag tcttgctgtt
    23221 gacgccactg tccatggtga tttcacgctt tattgccaag agatcctatc atctcttcca
    23281 gaagcaaaca gagacgaggg gaattcagac tcagttgatt gaagaatcgc ttagccagca
    23341 gactataatc cagtccttca atgctcaaac agaatttatc caaagattgc gtgaggctca
    23401 tgacaactac tcaggctatt ctcagtcagc catcttttat tcttcaacgg tcaatccttc
    23461 gactcgcttt gtaaatgcac tcatttatgc ccttttagct ggagtaggag cttatcgtat
    23521 catgatgggt tcaaccttga ccgtcggtcg tttagtgact tttttgaact atgttcagca
    23581 atacaccaag ccctttaacg atatttcttc agtgctagct gagttgcaaa gtgctctggc
    23641 ttgcgtagag cgtatctatg gagtcttaga tagccctgaa gtggctgaaa caggtaagga
    23701 agtcttgacc agtgaccaag ttaagggagc tatttccttt aaacatgtct cttttggcta
    23761 ccatcctgaa aaaattttga ttaaggagtt gtctatcgat attccagctg gtagtaaggt
    23821 agccatcgtt ggtccgacag gtgctggaaa atcaactctt atcaatctcc ttatgcgttt
    23881 ttatcccatt agctcgggag atatcttgct ggatgggcaa tccatttatg attatacacg
    23941 agtatcattg agacagcagt ttggtatggt gcttcaagaa acctggctca cacaagggac
    24001 cattcatgat aatattgcct ttggcaatcc tgaagccagt cgagagcaag taattgctgc
    24061 tgccaaagca gctaatgcag actttttcat ccaacagttg ccacagggat acgataccaa
    24121 gttggaaaat gctggagaat ctctctctgt cggccaagct cagctcttga ccatagcccg
    24181 agtctttctg gctattccaa agattcttat cttagacgag gcaacttctt ccattgatac
    24241 acggacagaa gtgctggtac aggatgcctt tgcaaaactc atgaagggcc gcacaagctt
    24301 catcattgct caccgtttgt caaccattca ggatgcggat ttaattcttg tcttagtaga
    24361 tggtgatatt gttgaatatg gtaaccatca agaactcatg gatagaaagg gtaagtatta
    24421 ccaaatgcaa aaagctgcgg cttttagttc tgaataagcc attctctttt gaaagtttat
    24481 ggacgaaaaa agttgccttc gagtgacttt tttgttacaa tagctagaaa aattgttcac
    24541 tgtaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc
    24601 acagctttga ggttgtagat aagactgacg aagtcagctc aaaacactgt tttgaggttg
    24661 cagatagaac tgacgaagtc agtaaccaca cctacggcaa agtgaatctg aagtggtttg
    24721 aagagagtac aacttgtctt ttagaaaagg agcctacaat gaaagtcttt cagcatgtaa
    24781 atatcgtgac ttgtgatcaa aatttccatg tttatcttga tggaatctta gcagtcaagg
    24841 attctcaaat cgtctatgtc ggtcaagata agccagcgtt tttagaacaa gctgagcaga
    24901 ttatagacta tcagggagct tggattatgc ctggtttggt caattgtcac acccattctg
    24961 caatgacagg tctgagaggg atccgagatg acagcaatct ccatgaatgg ctcaatgact
    25021 atatctggcc agcagaatct gagtttactc ccgacatgac taccaatgcg gtcaaagaag
    25081 ccttgacaga gatgctccag tcaggaacaa caacctttaa cgatatgtat aatcccagtg
    25141 gtgtggatat ccagcaaatt tatcaggcgg tgaaaacttc caagatgcgt tgttattttt
    25201 ctccgactct cttttcttca gagacagaaa caactgctga gactataagc agaactcgat
    25261 ccatcataga cgaaatctta aaatataaaa atccaaattt caaggttatg gtagcacctc
    25321 attctccgta tagctgcagt agagacttgc tggaagcgag tttggaaatg gcaaaagagc
    25381 taaatattcc gctccatgtc catgtggcgg agaccaagga ggagtcagga attatcctca
    25441 aacgatacgg caaacgcccc cttgcttttc ttgaagaact gggttattta gatcatccgt
    25501 ccgtatttgc tcacggggtc gaattaaacg agagagaaat tgaacgcttg gcatcttctc
    25561 aagtggctat cgcccacaat cctatcagta acctcaaact ggcatcagga attgctccaa
    25621 ttatccagct ccaaaaagcg ggagtagcag tcggaattgc gactgactcg gttgcttcca
    25681 ataacaatct agatatgttt gaggaaggaa ggactgcagc tcttcttcag aagatgaaaa
    25741 gtggggatgc cagccagttt ccaatcgaaa cagctctcaa ggtactgaca atcgaagggg
    25801 ctaaggtcct tggaatggaa aatcagatag gaagtctgga agtcggcaag caagcagatt
    25861 ttctggtcat tcaaccacaa gggaaaattc atctccaacc tcaggaaaat atgctgtctc
    25921 acctggttta tgcagttaaa tctagtgatg tagatgatgt ttatatcgcc ggagaacagg
    25981 ttgttaagca aggtcaagtc ctgacagtag aactttaaaa gaaaaat
//
LOCUS       DAVLUM010000029        24148 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLUM010000029 DAVLUM010000000
VERSION     DAVLUM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.029"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(50..3226)
                     /gene="carB"
                     /locus_tag="VYN42_001048"
     CDS             complement(50..3226)
                     /gene="carB"
                     /locus_tag="VYN42_001048"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1462135.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3539..4618)
                     /gene="carA"
                     /locus_tag="VYN42_001049"
     CDS             complement(3539..4618)
                     /gene="carA"
                     /locus_tag="VYN42_001049"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1462136.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALAKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4668..5591)
                     /locus_tag="VYN42_001050"
     CDS             complement(4668..5591)
                     /locus_tag="VYN42_001050"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1462137.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5610..6131)
                     /gene="pyrR"
                     /locus_tag="VYN42_001051"
     CDS             complement(5610..6131)
                     /gene="pyrR"
                     /locus_tag="VYN42_001051"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1462138.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6342..6971)
                     /gene="nth"
                     /locus_tag="VYN42_001052"
     CDS             complement(6342..6971)
                     /gene="nth"
                     /locus_tag="VYN42_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1462139.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(6971..7513)
                     /locus_tag="VYN42_001053"
     CDS             complement(6971..7513)
                     /locus_tag="VYN42_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1462140.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVGDLRARNQEILDIKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7683..8000
                     /locus_tag="VYN42_001054"
     CDS             7683..8000
                     /locus_tag="VYN42_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1462141.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            8239..9798
                     /locus_tag="VYN42_001055"
     CDS             8239..9798
                     /locus_tag="VYN42_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1462142.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETTLRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGIGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9947..10846)
                     /gene="htpX"
                     /locus_tag="VYN42_001056"
     CDS             complement(9947..10846)
                     /gene="htpX"
                     /locus_tag="VYN42_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1462143.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALVSAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10848..11408)
                     /locus_tag="VYN42_001057"
     CDS             complement(10848..11408)
                     /locus_tag="VYN42_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1462144.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11502..12215
                     /gene="rsmG"
                     /locus_tag="VYN42_001058"
     CDS             11502..12215
                     /gene="rsmG"
                     /locus_tag="VYN42_001058"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1462145.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12518..13801
                     /locus_tag="VYN42_001059"
     CDS             12518..13801
                     /locus_tag="VYN42_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1462146.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(13996..15567)
                     /gene="ffh"
                     /locus_tag="VYN42_001060"
     CDS             complement(13996..15567)
                     /gene="ffh"
                     /locus_tag="VYN42_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1462147.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15579..15911)
                     /locus_tag="VYN42_001061"
     CDS             complement(15579..15911)
                     /locus_tag="VYN42_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1462148.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(16002..16379)
                     /locus_tag="VYN42_001062"
     CDS             complement(16002..16379)
                     /locus_tag="VYN42_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1462149.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16451..17755
                     /locus_tag="VYN42_001063"
     CDS             16451..17755
                     /locus_tag="VYN42_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1462150.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAVHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17768..18574
                     /gene="yidA"
                     /locus_tag="VYN42_001064"
     CDS             17768..18574
                     /gene="yidA"
                     /locus_tag="VYN42_001064"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1462151.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(18629..18700)
                     /locus_tag="VYN42_001065"
     tRNA            complement(18629..18700)
                     /locus_tag="VYN42_001065"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18665..18667),aa:Arg,seq:cct)
     gene            complement(18742..19089)
                     /gene="rplS"
                     /locus_tag="VYN42_001066"
     CDS             complement(18742..19089)
                     /gene="rplS"
                     /locus_tag="VYN42_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1462152.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(19208..19537)
                     /gene="crcB"
                     /locus_tag="VYN42_001067"
     CDS             complement(19208..19537)
                     /gene="crcB"
                     /locus_tag="VYN42_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1462153.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLILTYLGGLVA
                     IFLGILL"
     gene            complement(19531..19905)
                     /gene="crcB"
                     /locus_tag="VYN42_001068"
     CDS             complement(19531..19905)
                     /gene="crcB"
                     /locus_tag="VYN42_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1462154.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(19902..20168)
                     /locus_tag="VYN42_001069"
     CDS             complement(19902..20168)
                     /locus_tag="VYN42_001069"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1462155.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(20284..20727)
                     /locus_tag="VYN42_001070"
     CDS             complement(20284..20727)
                     /locus_tag="VYN42_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1462156.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            20831..21766
                     /locus_tag="VYN42_001071"
     CDS             20831..21766
                     /locus_tag="VYN42_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1462157.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            21820..22104
                     /locus_tag="VYN42_001072"
     CDS             21820..22104
                     /locus_tag="VYN42_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1462158.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(22161..22739)
                     /locus_tag="VYN42_001073"
     CDS             complement(22161..22739)
                     /locus_tag="VYN42_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV1462159.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(22714..23727)
                     /gene="efeB"
                     /locus_tag="VYN42_001074"
                     /pseudo
     CDS             complement(22714..23727)
                     /gene="efeB"
                     /locus_tag="VYN42_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            complement(23730..24148)
                     /locus_tag="VYN42_001075"
                     /pseudo
     CDS             complement(23730..24148)
                     /locus_tag="VYN42_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         7095 a         5449 c         4608 g         6996 t
ORIGIN      
        1 atccctgtgt actgttctaa attcagtctg ctatatctta tttttctatt taaatcgctt
       61 ctgtaacaaa gctacgactt tcaagtacct taagcatggc attagctgta tctagcgctg
      121 tgaagagggg caccccgtgt tcaatggctg aacgacgaat ttgctcacca tcttcgtcag
      181 cagttcgttt tgttcctact gtgttaatga tagcttgaat tcttcctttg cgtacaaaac
      241 ttgggatatc cttatcgtca tcaccaatct taccaacagg ttgggcttgc aagccatggc
      301 tagcaaagaa ggctgctgtc ccttctgtcg caaggattcc ataaccaatg ttttggaaac
      361 gacgagccaa gttcaaggct tcttctttgg catcatcagc gatggtaaag acgacattac
      421 caaaagttgg caagtgtaga taagaagctt caaaggcttt atagagagct ttttccaaag
      481 tagcatcaga acccataact tcacctgttg acttcatttc aggaccgagc aagctgtcta
      541 ccttagctag tttggtaaag gagaagacag gtgccttgat atgaacacgg gtgctttcag
      601 ggtaaagtcc attttggtag ccaagttctg ataaactttg accaagaatg agcttggtcg
      661 ctacttgagc cataggaata ttggttacct tagataggaa tggaacagta cggctggcac
      721 gtggattgac ctcaataacg tagacttttt catccttgat aacaaactgg atgttcatca
      781 ttccaaggca gtgaagaccg attgctaagc gtttggtgta gtctgcgatg gtctcctgaa
      841 ccttttgcga caaggtttgt ggtgggtaaa cagccattga gtcacctgag tggacaccag
      901 cacgttcgat atgctccatg ataccaggaa tgagcacatc tttaccatct gaaatggcat
      961 caacttcgca ctcttgccca acgatataag agtcgacaag aactgggtga tctggactag
     1021 ccttaacagc agttcgcatg taagaacgaa ggtcttcttc gttttcaacg atttccatgg
     1081 cacgtccacc aagtacataa gatgggcgga caagaactgg gaagccaatc ttacgagctg
     1141 caagagctgc ttcttcttca ttggtagccg tttgtcctgg tggctgtgga atatccaatt
     1201 ctttgagagc ttgctcgaag aggtcacggt cttcggcacg gtctaggtca gcaacctgtg
     1261 taccaaggat ggtcacacct gcttttgcca atggctccgc aaggttgatg gctgtttgac
     1321 caccaaactg aacgataact ccctttggtt gttccaagtc aatgacgttc ataacatctt
     1381 cgaatgtcaa tggctcaaag taaagcttat ctgatacaga gaagtctgtt gaaacggtct
     1441 ctgggtttga gttcatgatg atagcttcat aaccagctgc ctggatagcc ttaacagagt
     1501 gaacggttgc gtagtcaaac tcaacccctt gaccaatacg gattggacct gaacctagga
     1561 caagtacaga ttctttatca gatctgatag attcattttc ccaaccatag gttgaataga
     1621 aatatggcgt ttcagagtcg aactctgccg cacaagtatc taccatctta taaactggaa
     1681 caatcttgtt ttccaagcga agttggcgaa cttgatcatc agtcgttccc cagagttcag
     1741 caatcttacg gtctgagaaa ccattaagtt tggctgtttt caaaacttct agatcttgtg
     1801 gatgagcacc caattcttgc tcaatttcaa agatatgcaa gagtttatca agatagaaga
     1861 tatcaatttt tgtaagctct gcaatttctt caggtgtgta gccacgacga atggcttctg
     1921 atacgtagaa gagacggtca tcttgggctt tgacaacctt ttcaatcaag gcatcatcag
     1981 aaactgctgc aagttcaggt atttcattgt ggtgcacccc aatttcaagg gagcggcagg
     2041 ccttgagaag agattcctcg atgttacgac cgattgccat gacttctcca gtcgccttca
     2101 tttgtgtacc gagacggcgt tcaccctttt caaacttgtc aaatgggaaa cgtggaatct
     2161 tagcaactac gtagtcaagg gctggttcaa acatggcata ggttgaacct gtaactgggt
     2221 ttataacctc atccaaggtc aaacctactg caatcttggc agccaactta gcaatcggat
     2281 atcctgtcgc tttagaagca agggctgacg aacgtgatac acgagggttt acttcgataa
     2341 cataatactt gaagctgtta ggatcaagag ctagctgaac attacatcca ccttcaatct
     2401 tgagggcgcg aataatgctc aagctcgcat cacgaagcat ttggttttca tagtctgaca
     2461 tggtttgcgc aggggcaaat acaatggaat cccctgtgtg aatcccaact gggtcaaagt
     2521 tttccatgtt acaaacaacc aaggcattgt cagctgagtc acgcatcact tcgtattcaa
     2581 tttccttgaa accggcaatc gaacgctcaa tcaaacattg ggtaacaggt gacaatttca
     2641 aaccattttc agtgatttca cgcaattctt tttcgttggc acacatacca ccaccagtac
     2701 caccaagggt aaaggctgga cgaacgatga ctgggtagcc aattgtcgct gcaaaggcaa
     2761 ctgcttcttc tactgtgtta acaatttcag attctggaat gggttgctca agctcttcca
     2821 tcaattgttt aaagaggtca cggtcctccg cttggtcaat ggcagacaat ttagtaccga
     2881 gaagctctac accaagctca tctaagatgc catttttaga caattccatg gccatgttga
     2941 gacctgtctg accaccgagt gttggtagca aggcatctgg acgttcctta cgaagaatac
     3001 gtgtcacaaa ctcaagtgta atcggttcaa tgtaaacctt gtcagcaatt tccttgtccg
     3061 tcatgatggt tgcaggattt gagttaacca aaacaacctc ataaccttcc tctttcaacg
     3121 acaagcaagc ctgggtccca gcgtagtcaa actcagcagc ctgaccaata ataatcggac
     3181 cagaaccaat caccataatt ttttgaatat cagtacgttt aggcatatat aagatattaa
     3241 gggcgtcaag cggacaaagc taaaatagga gttatgacga agaactgtca gttctaggaa
     3301 taactatctt tttagcaccg tccgtagccc gtattcagtt cagcaaatac ggagcaccct
     3361 tctcctttct attcgtcgcc tctcagggcg acattaaata agatacaaag gacgaataga
     3421 aagcgattga attttaagaa atcaaggaag gattgacaat ccaagttggt ttctctaaat
     3481 tctgagcttt ccgtccgtgt tcagttacat aaattctccg acgagctttt actcgttctt
     3541 agtttgattg tttaaaaact tccatcatct cgataaactc gtcaaatagg tagctagcgt
     3601 cgtgtggccc aggagctgca tctgggtggt attgaacaga gaaagcaggt tggtatctgt
     3661 ggcgcacacc ttccactgac ttgtcattga tttcttcgtg ggtaataatc aagtgctctg
     3721 gcaaatcctc gcggctgact gcataaccat ggttctggct ggtgaagtct actcgtcctg
     3781 ttgcgatttc acgtaccgca tggttgaatc cacggtggcc aaacttcatc ttataggtct
     3841 tagccccgtt tgccattgca aagagttggt gtcccataca aataccaaag attggaattt
     3901 ttccttgtac accgcgaatc atgtcgagtg cttgtggaac gtcttctggg ttacctggac
     3961 catttgacaa cataactcca tcaggattga gatggagaat ttcttcagcc gttgtcgaat
     4021 aaggaacaac tgtcacgtta cagttgcgtt tagaaagttc acgtaggatt gagtgcttga
     4081 gaccaaagtc cactagcacc acgctcaaac caactcctgg agctggataa gacgttttag
     4141 tagaaacctg tttgatattg tctgtcggta aaactgttgc ttggagctgg tccgtcacat
     4201 ggtccatact gtccccaaca tgggtcaagg ttgcacgcat agtaccatgc ttacggataa
     4261 tcttggcaag agcacgcgta tcaattcctg aaatccctgg aattttcttg gctttcaaaa
     4321 attcatccaa ggtcatttgg ttgcgccagt tgctagctct acgcgcttct tcaaaaacaa
     4381 cgactccctt acaagttgga ataatggatt cataatcatc acgattaata ccataatttc
     4441 ctaccaaagg ataagtaaag gtcaagattt gtccattata agactggtct gtaatggatt
     4501 cttggtagcc ggtcatccct gtattaaaga cgatttcgcc tgttacatca atatctgctc
     4561 cgaaggcctt gccttcaaaa actgtgccat cttctaatac tagaattctt tttgtcatat
     4621 tttcacctct cgtggacgct cactggcgtc ttttaacgtc ttgtgtttta gttggcgttt
     4681 ctactcgcta gtacggattc taagattgcc attcgaacaa agacaccatt ggtcatttgt
     4741 tggacaatcc gtgattttgg tgcttcaacc aagtggtctg ctatttctac atcacgattg
     4801 attggagctg ggtgcatgag gattgctgtt tctttcaaac gatcgtaacg ttcttgagtc
     4861 aagccatgtt gggcatggta gtcttctttt gaaaatacag ctccactatc atggcgttcg
     4921 tgttgcacac ggagaaacat catgacatca acctgatcaa tgatttcatc aatggttaca
     4981 aactttccat agtctgcaaa ctcttgactt ctccattcct caggtccagc gaaaaagagt
     5041 tcagctccca agcgtttcaa aatctgcata ttggatttgg caacgcgtga gtggtccaag
     5101 tcacctgcaa tagcaacttt aagaccctca aagtggccaa attcctcata aatggtcatc
     5161 aaatcaagca agctctggct agggtgttgg cccgaaccat ctccaccatt gatgatggaa
     5221 gtcgtaatcg ttggactagc aatcaattct ctatagtagt cgacctctgg atggcgaatc
     5281 acacagacat ccactcctaa agcagacaga gtcaaaatgg tgtcataaag tgtctcaccc
     5341 ttattaaccg aactagtctt cacatcaaag tcaagtcgtt ccaatccaag tttaatctct
     5401 gcgacttcaa aggacttatg tgtccgtgta gaatcctcaa agaagagatt ggaaacaatc
     5461 ggatggtctt catagggaag ctgggctcca tttttaaact caattcctcg cttgatcaat
     5521 ttcattactt gatcgacagt gaggtcttcc atggacacca catggttcaa tgcttgttga
     5581 ttttctgaca tggctactcc tttaactttc taagcttctt cagtaatcag aactctgtct
     5641 tggtcatcaa gttctgtcat ctctacgatg atttcttcag aacgactggt tgggatattt
     5701 tttccaacgt aatctggacg gattggcaat tctctatgtc cacgatcgac tagaactgct
     5761 aaactcacac gcgcaggacg accatgaccg acaatattat caatagcagc acggatggta
     5821 cgacctgtat agagcacatc atccaccaag ataacttcgc ggtctgtcac atcgacagaa
     5881 accaaagaag tatcttctcc acttttaaca tcatcacgga aaggtttagt atccaattcc
     5941 acaacaggaa ctgaaagatt ttctaactgc ttcaaacgtt cttggattcg gtgggcaata
     6001 aagacaccac gagttttaat accagccaag acgatcttat tcaaatcttt gttgcgttcg
     6061 ataatctcat aagtaatacg cgtaatcgct cgtttgacgg tcaattcgtc tacaacttct
     6121 tttgttttca tgacaaacct ccaaaaagaa aagtctcctt aaacaaggag acttgaaatt
     6181 tatagccaag cgagccctac tgcacacagt atagacttca cccttctact ttatcgcgct
     6241 ccttgcctgc ctcacgggac aggtttaaag gaatatttag ttatcattta ctatagcaca
     6301 aagcatgctt aaaatcaagc aaaaagtttc aatgtagcat cttacaaatt gctaaaatca
     6361 tataattgtg ggtactggtc acactctgga ttttttggat ggcaaatggc tcttccaaaa
     6421 taaatcatgg cctgatgggc agctaaccac tgctcaggcg gcaagatatc catgacccgc
     6481 ttttccacct caagtggcgt cgctgatttt ttgacaatat cgtggtgttt gcaaatacgc
     6541 tccacatgag tatccactgc aaaggctgga atcccaaatc ctacactcat gacaacattg
     6601 gctgtcttgc gaccaacacc tgccaaactc tccaattctt cacgtgtctg agggacttga
     6661 ccatcaaaat cgtctagtaa ctgttgggca cattttttaa ggaatttagc tttattccga
     6721 tacaatccca agcgagaaat atgtgaagca atctcactct ctgtcgctac agacatagct
     6781 tggggtgttg gaaaggcaac aaagagacct ggtgtggcct tatttaccgc tgcatctgtc
     6841 gtctgggctg ataacatgac cgcaaccagg agttcaaaat gattggtaaa atcaagacta
     6901 ggcttggcat ctgggaagag ggcaatgatt tcttctagca cctttcgtgc tcgttttttt
     6961 gacaagacca ttattcatct ccgtcaaata gtccttgtaa gccagcaaaa ggactgtttt
     7021 cttctttctt tactgctttt tgagcttggt attcttcctc tgtcatgatt tgccagtcat
     7081 ttcctgagat aaatccttga ccagcttctt cttcagccgt caagaccttg ataggaatgt
     7141 ttagcaggat attgtctgat acactctcag caaggtcaag ctccccattt tcgatgggca
     7201 agaccaagtc atcatctaaa acttcttgat ctagctggtt agttgcgcct tccatgaaaa
     7261 cttccgtgac tggataagat tcaactaact caactggctc catactgcga ctcgaagcaa
     7321 gaacaatggt ataagatagt tgataatcta agaaatacat acggtcttca tattgtactt
     7381 tcccaactgc aaggatatct tttatatcta aaatttcttg attacgtgca cgcaggtcac
     7441 caactaaatc taacgtttgt tcaaagttca aaccttcaga ctgcttacga atttcttgaa
     7501 tatttaattt catacttcct ccataaagat ttactctctt gattatacca tgaaaaggct
     7561 acaaatcagc acaccaaact ttgtaattaa aattcaaaat tttaacatat ttactatgac
     7621 agttttgttt tttagtgcta tactataggg aaagagtaca tcagatcaag gaggatgctc
     7681 acatggaaga caagaaactc attcaactcc tatccaagtt aaataaaagc taccaaaact
     7741 gtaaacaggg tacggcagat gatattcgac tacaagagct gctaaacact actatgcaag
     7801 agctcaaaaa aacggaaaag ttgaacaaca gtatcttaat tgatcttgag aaattttacc
     7861 aacccaccag tcctctgatt ggactgggta gcctaaaact aaacaatcaa gcacgcactg
     7921 cttggcgaaa ctatgataaa ttccattacg agcatgtcaa acacgtacta agtctctatg
     7981 gacctgtttt tgaattttag agcatagaat ttccagtttt ctgttgacaa aatttcctta
     8041 aaggtataat ataaagatac taatactcgg aggtaaggga gacatgaaca actaagtcta
     8101 tcaaataaag aacctttatt tagtagatct tgtttttgtc tctttttgtg tgctctttta
     8161 tgctcttttt ctggcatgtt aatagagttt ttttgacata gactttgggc tctactaggt
     8221 aaagtagagc tttttgttat gcactatgaa cattctagaa agggaaatca tatgataaaa
     8281 atcaatcatc taaccatcac acaaaacaaa gatttacgag atcttgtatc tgacctaacc
     8341 atgaccatcc aagacgggga aaaggttgct attattggtg aagaaggaaa tggcaaatca
     8401 accttactta aaattttaat gggggaagct ttgtctgatt tcactatcaa gggaaacatc
     8461 caatctgact atcagtcact ggcctacatt cctcaaaaac ttcccgagga gctgaaaaag
     8521 aaaactttac acgactactt ctttttagat tctattgatt tagactacag tatcctctat
     8581 cgtttggcgg aggaattgca ttttgatagc aatcgtttcg caagtgacca agagattggc
     8641 aatctatcag ggggagaagc tttgaaaatt cagcttatcc atgagttagc caaacccttt
     8701 gagattctat ttttagatga accttcaaat gacctagacc ttgagacagt tgattggcta
     8761 aaaggccaga ttcaaaagac caggcaaacc gttattttca tttcccatga tgaagacttt
     8821 ctttctgaaa cggcagacac tattgttcac ttgcgactgg tcaaacaccg taaagaagcg
     8881 gaaacgctag tagagcattt agactatgat agctatagtg agcagagaaa ggctaatttt
     8941 gccaaacaaa gtcagcaagc tgctaacaac caaagagcct acgataaaac catggaaaaa
     9001 catcggagag ttaagcaaaa tgtagaaact acgcttcgag ctaccaaaga tagtactgcc
     9061 ggtcgcctat tgtctaaaaa gatgaaaact gtcctctcac aagaaaaacg ctacgaaaag
     9121 gcagctcagt ccatgactca aaaaccactt gaagaggaac aaatccaact tttcttttca
     9181 gacatccaac cattaccagc ttctaaagtc ttagtccaac tggaaaaaga aaatttgtcc
     9241 attgacgacc gtgttttggc tcaggaactg caactaactg tccgtggcca agaaaaaatc
     9301 ggtatcatcg gcccaaatgg tattgggaaa tcaactctgt tagccaaatt acagcaactt
     9361 cttaatgata aaagagagat ttcacttggt tttatgccac aagattacca caaaaaactg
     9421 caattggatt tatcctcaat agcttatatc agcaaaactg gggaaaaaga ggaacttcag
     9481 aaaatccaat ctcacctagc cagtctcaat ttcagttatc cagaaatgca gcatcaaatt
     9541 cgctccttat ctggcggaca acagggaaaa ctcctgcttt tggatttagt cctgcgcaaa
     9601 ccaaactttc tcctgctgga tgaacccaca cgaaactttt ctcccacttc tcaaccccaa
     9661 atcagaaaac tctttgcaac ctatccaggc ggtctcatca ctgtttcgca tgaccgtcgt
     9721 ttcttaaaag aagtctgctc gatcatctat cgcatgacag aacacggttt gaagctagtt
     9781 aatttagaag atttataaat ttgcaacata gcagataggt ggggcaaaaa cacaatttta
     9841 ggagaaaaag aagtaaatct tcccatagta aaacgcataa tatcaagttt tcacacctga
     9901 tattatgcgt ttttcagatt ttaaagactt ttttccagcc ttcattttac atctgtttta
     9961 aacgttcaat ccgttctgag ataggtgggt gggtataaaa gagtttttgg aaccccccac
    10021 ctttcttggg atcattgata taaagagcac tgctagcatc atcgacgtgg cgactcatag
    10081 gtttgctatt gtccaactta tctagggcat taatcattcc ctggggattg cgagtcagct
    10141 cgacactaga tgcatctgcc agaaattccc tctgacgaga aatagcgagc tgaaccaagg
    10201 ttgcagcgag aggtgccagt acaatagcta gtagggaaac cactagcata atgatttcaa
    10261 gaccatttcc atctcggtca tcatcacttc gtctgcgacc tgctccaccc caccacatca
    10321 tacgacctgc cataccagaa agcatggtga tagcactaac aagggcaact gcaatagtcg
    10381 aaatacggat atcataatta cgaatatgac tgacttcatg tcccataaca gcttctagtt
    10441 cttcacgatt catgatagct agtagacctg aagtcgcagc aacagccgca ttttgaggat
    10501 tagaacctgt cgcaaaggca tttaaggctg gatcatcaat gatgaaaaca cggggcatag
    10561 gaatctgagc gaccagagcc atatcttcca ctacatggta gaggtctggt gccgtttgct
    10621 catccacctc acgcgctcca ttcatggaca tgacaatctc tgtcgattga aaaatcatag
    10681 acaaagcgta gataaagccg ataatcagtg cgataaccaa accaccaagt ccagatctta
    10741 taaagagata accaaccgca taaccaacaa gagctaagag taggaaaaat accagcaaca
    10801 aaatccaggt ttttcgttta ttgcttgcaa tttgatcaaa caacatctta gtcacctaaa
    10861 ccgctaaaat caactttagg aaccgacttt tcctcttcag gtgtttgaag gaaatctgcc
    10921 gctttaaatc caaacattcc agcgataata ttgctcggga aagtttctaa ttttacattg
    10981 tagttgctga caacactgtt atagagttga cgagagtaag aaattttatt ttctgtgttt
    11041 gtcaactcct cttgcaattt aacaaagtta gcactagctt tcaaatctgg atagctttct
    11101 gcaactgcaa aaatacctga aacctgacga gtgagggcat cactggcttt catagcttct
    11161 gctggtgaag tcgctgccgc cacttggtta cgtagttctg ccaccttttc aagggtagaa
    11221 ccttcatatt tggcataacc ttttacagtc tcaatcaagt ttggcaagag atcattgcga
    11281 cgtttcaact gaacatcaat ctgactccaa gcctccttgg tttgcatacg atttttaacc
    11341 aaaccgttat agctaacaat cacaaaaata acaataagag cgataactcc aagaataatc
    11401 caagtcatga tataagtcct ttctactttt agattagtac cagtatatca aatttttaat
    11461 gattgtggta aaataagatg atactaaaga aggaaataac tatgaaacca gaaacatttt
    11521 acaacttgct tgccgagcag aatcttccac tttcgaacca gcaaaaagaa caatttgaac
    11581 gttattttga gctcttggtc gagtggaatg agaagattaa tttgacggcg attacggaca
    11641 aggaagaagt ttatctcaaa catttttacg attcgattgc acccattctt caaggtttga
    11701 ttcccaatga aactatcaaa cttcttgata tcggggctgg ggcaggattt cctagtctac
    11761 caatgaaaat tctctatccg gagttagatg tgaccattat tgattcactc aataagcgca
    11821 tcaacttcct acaactcttg gctcaagaac tggatttgaa cggagttcat ttctaccacg
    11881 gacgtgccga agattttgcc caagacaaga acttccgtgc tcaatatgat tttgtaacag
    11941 ctcgtgcggt tgcccgtatg caggtcctat ctgaattgac tattccctac cttaaggttg
    12001 gtggaaaact attggcactc aaggccagca atgcgcctga ggagttgtta gaagctaaga
    12061 atgccctcaa tctccttttt agtaaagtcg aagacaatct cagctacgcc ctaccaaata
    12121 gagatccgcg ttacatcaca gtggtagaaa agaaaaaaga aacaccaaat aaatatccac
    12181 gtaaggctgg tatgccaaat aaacgcccgc tttaaatttt taagtaaaaa aatatttaca
    12241 aaatcaacct cgctctctta tttttaggct cgggaaaaaa tgatttacaa aatcagcctc
    12301 gctcttttat ttctaggctc gggaaaaaat gatttacaaa atcatttttt tctgctatac
    12361 tatcctaagc aaaggttttt aatgtcatcc cgtgaggtga cgaagacgca gaaatattta
    12421 aaactcttta aaatctaaat tttaaagaag tcttactctg agggcctatt gctgtaaaat
    12481 aatgggctct tttttgatgc ccaaaagtga ggtttatatg aaacaagaat caactgttga
    12541 tttgttatta gacgttgacc aacgtccttc ggctggaaaa ggaattctcc ttagcttcca
    12601 acacgttttc gccatgtttg gtgcgaccat cttggtacca ttgattttgg gaatgcctgt
    12661 atctgttgcc ctttttgctt caggtgttgg aacactcatc tacatgattg ctactggttt
    12721 taaagttcca gtttatctag gttcttcatt tgcctttatc acagctatgt cactggctat
    12781 gaaagaaatg gggggtgatg tatctgctgc ccaaacaggg gttatcttga ctggtttagt
    12841 ctatgtcctt gttgctacca gcatccgatt tgtaggaaca aaatggattg ataaactctt
    12901 gccaccaatc attatcggtc ctatgatcat cgttatcggt cttggacttg caggttcagc
    12961 tgttaccaat gcaggtcttg tagcagacgg aaattggaaa aatgctctgg tagccgttgt
    13021 tactttccta attgctgcct ttatcaatac aaaaggaaaa ggcttcctac gaatcattcc
    13081 attcctcttt gccattatcg gtggttacct tttcgcacta actcttggct tggttgactt
    13141 tacaccagtt cttaaagcca actggttcga aattcctggt ttctacttgc catttagcac
    13201 aggtggtgcc tttaaagagt acaatcttta ctttggtcca gaagccatcg ctatcttgcc
    13261 aatcgctatc gtaacaattt ctgaacatat cggagaccat actgttttgg gtcaaatctg
    13321 tggccgtcaa ttcttaaaag aaccaggtct tcaccgtact cttcttggtg acggtatcgc
    13381 aacttctgtt tctgccttcc ttggtggacc agccaataca acttacggag aaaatacagg
    13441 ggttatcggt atgactcgta tcgcttctgt ctcagttatc cgtaacgctg ccttcatcgc
    13501 gattgccctc agcttccttg gtaaattcac tgccttgatt tcaactattc caaacgctgt
    13561 acttggtggt atgtcaatcc ttctctatgg ggttatcgcc agcaatggtt tgaaagtctt
    13621 gattaaagaa cgtgttgatt tcgctcaaat gcgaaacctc atcatcgcaa gtgctatgtt
    13681 ggttcttgga cttggaggag ctatccttaa acttggtcca gttacacttt caggtactgc
    13741 cctttcagcc atgacaggaa tcatcttgaa cttgatcttg ccatacgaaa ataaagacta
    13801 agagtctaaa tacacctaat ccactcagac agctgagtgg atttttcgta tattataata
    13861 aaagtgtctt aacaaaatta ttaaaatcaa aaaacgtata atatcagata ttctaaaacc
    13921 ttgatactgt acgttttatc atagaaattt ttactttatt ttctcatcaa atgagatttg
    13981 catcaatctc ttgtcttact tgcgtttctt cttcgctttc ttcattttgt tagccatacg
    14041 tttcatggac tgtttcatgg caaattcacc aattttacct ttcaaaccgc caccaaacat
    14101 ctggctcata tctggcattc ctgctcctcc gagagctgat aagtcaggca taccgccttg
    14161 tcccatcatt ccttcaaggg cagacatatc cattcctccc atatttggca tatttttagg
    14221 aaggttattt ggattaatcc ccatttgctt catcatttta ttcatatccc cagacataac
    14281 accctgcatg agctgtttag cctggttaaa gtccttgatg aatttattga cttcgacgaa
    14341 tgtatttcca gaaccagcag caatacgacg gcgacggctt ggatttaaca aatctgggtt
    14401 ttcacgttct tcaggtgtca tcgaagacac aatcgcacgt ttacgagcaa tctggcgttc
    14461 atccaccttc atgttttgaa gggctggatt gttggccata cctggaatca tcttgagcaa
    14521 gtcttccatc ggccccatat tttgcacctg atctaattga tcgatgaaat cattaaaatc
    14581 aaaggtgttt tcgcgcatct tctcagccat ttcaagggct ttttgttcat cgtattcctg
    14641 agaagctttc tcaatcaaag tgagcatatc ccccatacca aggatacggc tagacatgcg
    14701 gtctgggtgg aaggtttcaa tgtccgtaat cttttcacct gtaccagtga acttgattgg
    14761 ttttccagta atgtgacgaa cagacagagc agcaccacca cgagtatcgc catcaatctt
    14821 ggtaaggatg accccagtca cttccaactg agcattaaac tcacgcgcaa cattggctgc
    14881 ttcctgacca atcatagcat caacgacaag caagatttca tttggttgag ccaatgcttt
    14941 cacatcacga agctcattca tgaggagctc atcaatctgc aaacgacccg cagtatcaat
    15001 caagacatag tcgttatgat tagtttgggc ttgctccaaa ccttgacgta caatctcaac
    15061 agctggtact tctgttccaa gtgcaaagac aggcacatca atctgttgtc ccaaggtctt
    15121 aagctggtca atggcagctg gacgataaat atccgccgca atcatcaaag gacgagcatt
    15181 ttcttctttc ttgagtttgt tggccaattt accagcaaag gttgttttac cagccccttg
    15241 taaaccaacc atcatgatga tggttggaat cttaggtgac ttgataattt ctgccgtatc
    15301 agaacctaaa acggctgtca gttcctcatc aacgatttta ataatctgtt gcgcaggatt
    15361 aagtgtatca atgacctcat gcccgactgc acgctcacga actttcttga taaagtcctt
    15421 tacaacaggc aaggcaacgt cggcctcgag caaggccaag cgaatttctt tggttgcctc
    15481 ttggacatca gattcagaga tttttccttt tttacgtaga tttttaaaga cgttctgcaa
    15541 acgttctgtt aaactttcaa atgccatttt tcttcctctt attctctatt atcaatgctt
    15601 gttaaaattt ctatctgctc ctgcagaaag tcatccttgg gatagcgctc caaaatctga
    15661 tcaaaaatct gactgcggac aatatagtcc gagtacatgt gcaatttcat ctcataatct
    15721 tccagaatct tttctgttcg cttgatattg tcatagacag cctgacgact gacaccgaac
    15781 tcctcggcaa tttcagcaag gctgtaatca tcagcgtagt agagctcgat ataattcatt
    15841 tgcttatctg tcaaaagcgc cgcataaaat tcaaagagcg cattcatacg attggttttt
    15901 tcgatttcca taacttttat tataccaaaa attagcctaa tctaccacac taggaagccg
    15961 atccaagaag atagatagct aaatttgaaa aagacatgag cctagcccca agtaatttcc
    16021 aattgatagc tggcaaaggg atgtccctct tgattttgta gttgataatc tagttcaatc
    16081 ttttgcctat caacttgata atggctcgtt tggatgataa actcctgcat gcccataggt
    16141 gtaggaatat aggctaaact atcgctatcc tttagaaagc gcataatggt cttgggatta
    16201 gaaaatcggc tcatcacaag ttcttgacca tgaaatttaa tcactacttt ttccttttcc
    16261 tcattataga aaagcaggta gctataatct cctttttcat gcacttccac atcataaagc
    16321 tggtcaatca cttccaactg ctcatcaaac tgaatcgtat ttcgcatccg aatcttcaca
    16381 tcaggccctc tttcttgtct cttgtcctac tattttacca aaaagagcag gattttgcta
    16441 taatggtcat atgaacgaaa aagtattccg tgaccctgtt cacaactaca tccatgtcaa
    16501 taatcaaatc atctatgact tgattaatac aaaagaattt cagcgtttgc gccggatcaa
    16561 acaactggga acttccagtt ataccttcca cggtggagaa cacagtcgct tctctcactg
    16621 tctaggagtc tatgaaattg cacgacgcat cacagagatt ttcgaagaaa aatatcctga
    16681 ggaatggaat cctgccgagt ctctcttgac catgaccgct gctctcctac acgaccttgg
    16741 gcatggtgcc tactcccata cttttgaaca tctctttgat acagaccatg aagccattac
    16801 tcaggagatt attcaaaatc ctgagacaga gattcaccaa gtcctgctac aagtggcacc
    16861 tgatttccca gaaaaggtgg ccagtgtcat tgaccatacc tatcctaata agcaggtcgt
    16921 gcagctcatt tctagtcaga ttgacgcaga tcgcatggac tatctcttgc gcgactccta
    16981 ttttacagga gcatcctatg gggaatttga cctgactcga atcctccgag tcattcgtcc
    17041 tatcgaaaat ggtatcgcct ttcagcgcaa tggcatgcac gccatcgaag actacgtcct
    17101 cagtcgctac cagatgtaca tgcaggttta tttccacccc gcaacacgcg ccatggaagt
    17161 tctcctacag aatcttctca aacgcgccaa ggaactctat cctgaggaca aggatttctt
    17221 tgcccgaact tctccacacc tcctgccttt cttcgaaaaa aatgtgacct tgactgacta
    17281 tctggctctg gatgatggcg tgatgaatac ctacttccag ctttggatga ccagtcctga
    17341 caagattctt gcagatttat cgcatcgctt tgtcaaccgc aaggtcttta aatccattac
    17401 cttttcacaa gaggaccaag atcaacttac tagcatgaga aaattggttg aggatatcgg
    17461 ctttgatccc gactactaca ctgccgttca taagaacttt gacctccctt atgatatcta
    17521 tcgtcccgaa tctgaaaacc cacggacaca gattgagatt ttacaaaaaa atggagaact
    17581 ggccgaactc tctagcctgt ctcctatcgt ccaatccctt gctggcagtc gccacggaga
    17641 taatcgcttt tattttccaa aagaaatgtt ggaccaaaac agcatctttg caagcattac
    17701 ccagcaattt ttacacttga ttgagaacga tcattttacc ccaaataaaa actagaagag
    17761 gaaatttatg agtattaaac taattgccgt tgatatcgac ggaacccttg tcaacagcca
    17821 aaaggaaatc actcctgaag ttttttctgc catccaagat gccaaagaag ctggtgtcaa
    17881 agtcgtgatt gcaactggcc gccctatcgc aggcgttgcc aaacttctag acgacttgca
    17941 gttgagagac gagggggact atgtggtaac cttcaacggt gcccttgtcc aagaaactgc
    18001 tacaggacat gagattatca gcgaatcctt gacttatgag gattatctag atatggaatt
    18061 cctcagtcgc aagctcggtg tccacatgca tgccattacc aaggacggta tctatactgc
    18121 aaatcgcaat atcggaaaat acactgtaca cgaatcaacc ctcgtcagca tgcctatctt
    18181 ctaccgtacc cctgaagaaa tggctggcaa agaaattgtt aaatgtatgt ttatcgatga
    18241 accagaaatt ctcgatgctg cgattgaaaa aattccagca gaattttacg agcgctactc
    18301 catcaacaaa tctgctcctt tctacctcga actccttaca aagaatgtag acaagggttc
    18361 agccattact cacttggctg aaaaactcgg attgaccaaa gatgaaacca tggcaatcgg
    18421 tgacgaagaa aatgaccgtg ccatgctgga agtcgttgga aaccccgttg tcatggaaaa
    18481 tggaaatcca gaaatcaaaa aaatcgccaa atacatcact aaaacaaatg acgaatccgg
    18541 cgttgcccac gccatccgaa catgggtact gtaaaaggaa agaatagact aaaaccgctc
    18601 agctgagcgg tttttgatgt ctaattactg ccccctgcag gaatcgaacc tgcaactact
    18661 ccttaggagg gagttgttat atccattgaa ctaagggagc tagataaaaa ctctgctgaa
    18721 aagcagagtt ttttagtcga attaacgacg gatttctttg atacgagctg ctttaccttg
    18781 aagagcacgc aagtagtaca atttcgcacg acgtacttta ccgtaacgaa caacttcgat
    18841 tttttcaaca cgtggagtgt ggattgggaa gatacgctca acacctacac cgttagagat
    18901 tttacgaact gtgtagtttt ctgagattcc agcaccttta cgtgcgataa caacaccttc
    18961 aaaaatctgg atacgttcac ggttaccttc gacaactttc gcgtgtacac gaacagtatc
    19021 accaggacgg aatgatggga tatctgtacg aagttgacct tcagtcaagc tttggattaa
    19081 tggattcatt ttattctcct atctttgtca atcttgagga atcttcctca gcggataaac
    19141 tgtatttttg tgcgtccatt acacacaaga tatagtttac caaatttcta aaaaaaagta
    19201 aagaaattta tagcaaaatt cctaaaaaaa tcgcaaccaa accacctagg taggtcaaaa
    19261 tcaggtaaga ataaaatacc ttcttatcgc ttagcaacct ttgaagttcg tcattcaagg
    19321 tcgaaaaagt tgttaaaccg ccacaaaatc ctgttgctag aatagcatat acttccttag
    19381 actctacatg attgtagaat actccaatta aaaaacaacc taaaagatta gctatgagcg
    19441 ttccgagtgg caatttagaa gcttgattat agcgagaaaa gaaataccgt acgagtgctc
    19501 cgaaaccaca agcaattgca agatagacga ttaccatttc ttcctcccta gaaaataagc
    19561 taagagtagg cctccaccga tgctcaaaag caaatacagg actaaactaa aataacgccc
    19621 tgtatcaagc agcttcacag tatcaagcat taggctggaa aaagttgtta aacctccgca
    19681 aaaacccgtc cccagtgcta aaatcaagcc cttactagtc cccttataga ccagatagcc
    19741 cttgacaaga aaaatcaagc agaaaattcc cagatagttg acaaagagag tgccccaagg
    19801 aaagtctgga ctggctggta accaggtgga aactagatat cggacaagtc cgcccaacat
    19861 agcagctaga aaaattccta gcggataaaa ttgttctttt ttcatttgat attttgatcc
    19921 tgataatcac gcgaacgttt gagtatgtcc gaaaaagtcg ctacaatagt ctcctgatag
    19981 cgcttgtcct ctacacgact cctaaccttt tcaaaaataa cttcttctct cttagtatct
    20041 aaaatcggtt tacctgaagc tttcttataa gcaaccaccc cctcaactaa atgcattcgt
    20101 tcttctaaca gtttgacaat ttggtcgtcg atttgatcga tttcttgacg aataatatct
    20161 aaatccatac agtctcctcc tttatttgaa ttattgtatc aaaaagccat caattaggct
    20221 agtaaaatcc caactctcga taagaaaaat gcactgattg attacatcag cgcactttta
    20281 tgtttatcct actttagcag ccaattcttc tgcgaattgt tccaagcgtt caatatcttc
    20341 ttcctcggca gaaagatcaa ctttaacaca ctctgaacct ttttctgctc ctgttgacac
    20401 aaagacacgg tcaaagtcat caacagcctt acagaattca tcgtagaagg tatctcctga
    20461 gccgaccact ccgtagattt tgccattcaa gttgagatct gctaggtctt cgtagaagtc
    20521 catcatctca tctggcaatt caccatcacc ataagtatag gtcgcaacga tagcgatgtc
    20581 tgcttccaag aagtctgaag cgtcaacagt tgtacattca tcaacatcaa catccaagcc
    20641 caagtcacgt aatttgtctg ctacaatatc tgcaatttct tcggtattac cggtcatact
    20701 ggcaaataca atttttgcta atgccatatc gtcctcctca atttatcttt ctccattata
    20761 tcacatcttt ttcattttaa aaataaaaat tcttgtgcta caatgaaatg agaaagaatt
    20821 gaggttattt atggagattt gccaacaaat tttagaaaaa attaaagaat acgacaccat
    20881 tatcattcat cgtcatatga aaccagaccc tgatgccttg ggaagtcagg tgggattgaa
    20941 agccttgctg gaacatcatt tcccagaaaa aaccatcaaa gccgtcggtt ttgatgaacc
    21001 aactcttact tggatggctg agatggatct tgttgaagat agagcctacc aaggcgcact
    21061 tgtcatcgtc tgtgatacag ctaatactgc tcgtatcgat gataagcgct atagtcaagg
    21121 tgattttctc attaagattg accaccatcc aaatgatgat gtatacggtg acctgtcttg
    21181 ggtcgatact agttcaagta gcgctagcga gatgattacc ctatttgccc aaacaaccca
    21241 actagccttg gcagatcgcg atgctgagtt gctctttgca ggaattgtcg gtgatacagg
    21301 tcgcttcctc tacccttcta ccactgcacg gactcttcgc ctggctgctt atttgagaga
    21361 acataacttt gactttgcgg ctctcactcg caaaatggac actatgagct acaaaattgc
    21421 taaactgcaa ggctacatct acgaccatct ggaagtggat gaaaatggtg ctgctcgcgt
    21481 tatcctgagt caagaagtct tgaaacaata caatgtaacc gatgctgaaa ctgcagccat
    21541 tgtcggtgca cctggacgca ttgacagagt gagtctctgg ggaatttttg tcgaacaggc
    21601 tgatggccac taccgagttc gcttacgcag taaaatccat cctatcaatg aaatcgccaa
    21661 ggagcatgat ggtggaggcc accctctagc aagtggtgct aattcctata gcctagaaga
    21721 aaacgaaatc atctaccaaa agttaaaaaa cttgcttaaa aactgataaa atacttgcca
    21781 aacttttcag aatctgatag actagtatgg taacaatcta tggctcgcaa agagaccatg
    21841 gcagaaagga aatattgcaa aatgaaaaaa gatatccatc cagaatatcg cccagttgtc
    21901 ttcatggaca caactactgg ttaccaattc cttagcggtt caacaaaacg ctctaacgaa
    21961 acagttgagt tcgaaggcga aacttaccca ttgatccgtg tggaaatttc atcagactca
    22021 cacccattct acactggacg tcaaaagttc actcaagcag atggacgcgt ggatcgtttc
    22081 aacaaaaaat acggtctcaa ataatgataa gagaacagtt tcggctgttc ttttttgttt
    22141 cttgaaatca actgctgttt tcatgttcca gactcatctg taggttcggt ttccatgcta
    22201 ctaggcagga aggaaatagc tgtttcaaca cgtccataat gagctgtact attgtcacga
    22261 accacacttt cattgatggt ccaagtggaa ttcattttct taaaagcttc tcggactttt
    22321 tccaaatctt tggaggcaat ggcctgttct aaggtttcaa aacgaggact tagacggttt
    22381 accaattttt ccttttccgc atctaggtca acaggatttt gttctttttc aaaagctaat
    22441 agagctgagg aaatttcggt gagtttggct tcagtaatat ctccagatag agctaacttt
    22501 tccttaacaa tcttaccaac ctcagaatcc ttattttcta ctctttcgaa gtctgatgcc
    22561 atcttcgtaa cgagtttctg ggtctcagtc tgaccaccat ttttaaccgt tttggatgca
    22621 tctgtgattt tcacaaagaa aaaactcaag ctttcttggg cacctgctgg ggaaagaatt
    22681 aaaaatgaca aagctaaaac tagtaaccag cttttagcct tccaataatt tctgaccaat
    22741 gtagcctcct ttctccacac caccaaagca agtaaaaagt ccactaccta tgtgagtgat
    22801 gtattcattc atcttatcag tagcacctag gttagtttga accttaacaa agttatcagg
    22861 atccttctgg aaagaaatga agagcaatcc cgtatcaaac tgaccagtct tttcatcaat
    22921 gccatctgag taagaataag aacgacgtaa aagtggctta tccacttctt tggccaaaca
    22981 aacatgcgaa tcatcaggta agagactcaa atccacttca tcaaactcat ttttcttacc
    23041 aaagggggca ccgctttcct tgtaacgacc aaaggtattt tcttgttctt cgagactagt
    23101 gcggtcccag gtctctaaaa acatctgaat ccgacgaact gccatataag aaccattttc
    23161 catccagtcc ttactatcag cccagataac gcggtcaaag tcttgctcct tggttggatt
    23221 tgctgttcca tccttaaaac caaagaggtt ccacggagtc tccattcgat ccccgatagc
    23281 tgcaaatcca gactgactcc aacgaagggg caccgcattt ctccccttac ggatgagatt
    23341 gcgaatagcg tgaaaggcaa tttgctcatc atctgcacaa gcatgaatca caatatctcc
    23401 accagtatat ttttcacgta attgctcctt aggaaataga ggtaaatccc tgaacagtcg
    23461 agggcgcttg ttttccaagt tcatcctttt caagaaactt gcagatacac caaaagtcag
    23521 cgtcaaacga tgaggattga gcccaactgt ctcaccagta tcgctcggag gaaagagagc
    23581 attctgtcca tcttttttaa ccaattcccc ctcgaccaac ttggcactat aatccgtcca
    23641 atccttgaat agctggataa ttttatctct atccgtcgta tgcaggtcca agacaacaaa
    23701 atagatattc ttttgcatgg gcgtactatt tggtacatca agcgaacctt acgaaaacgt
    23761 ctactatatt taaaccgctt tcttgtcttc ttgaattgag attttatttt tagacgcgac
    23821 aatggtttga gcgtctgctt tcttaggatg ttctggacgt ggcataatat ttcgccaacc
    23881 atggcgcttc aacagttgat agaaggcgtc acgtgtgtag gaacgaccta actccttttt
    23941 ataagcctga aataaggcat caattgtaac aaattctcct gactctgcag ccttcaaatg
    24001 acgggcaaga aaggctttct cttcctcaac tgtcatatat gcatggttac gaccaccacg
    24061 tgtttcttga aggagagagt cgagtccgaa ctcctcatat ttttttacat ttcgctaaat
    24121 cgttgtttga ttacagtcta aaagttct
//
LOCUS       DAVLUM010000030        23313 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLUM010000030 DAVLUM010000000
VERSION     DAVLUM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.030"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            646..2799
                     /locus_tag="VYN42_001076"
     CDS             646..2799
                     /locus_tag="VYN42_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1462160.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2812..4161
                     /locus_tag="VYN42_001077"
     CDS             2812..4161
                     /locus_tag="VYN42_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1462161.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4331..5038
                     /locus_tag="VYN42_001078"
     CDS             4331..5038
                     /locus_tag="VYN42_001078"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1462162.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5240..8965
                     /locus_tag="VYN42_001079"
     CDS             5240..8965
                     /locus_tag="VYN42_001079"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1462163.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYISMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVAREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEATLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIVRGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9058..10500
                     /locus_tag="VYN42_001080"
     CDS             9058..10500
                     /locus_tag="VYN42_001080"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1462164.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10537..11559
                     /locus_tag="VYN42_001081"
     CDS             10537..11559
                     /locus_tag="VYN42_001081"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1462165.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11556..12101
                     /gene="purN"
                     /locus_tag="VYN42_001082"
     CDS             11556..12101
                     /gene="purN"
                     /locus_tag="VYN42_001082"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1462166.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12185..12694
                     /locus_tag="VYN42_001083"
     CDS             12185..12694
                     /locus_tag="VYN42_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1462167.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSNLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12719..14266
                     /gene="purH"
                     /locus_tag="VYN42_001084"
     CDS             12719..14266
                     /gene="purH"
                     /locus_tag="VYN42_001084"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1462168.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14388..15650
                     /gene="purD"
                     /locus_tag="VYN42_001085"
     CDS             14388..15650
                     /gene="purD"
                     /locus_tag="VYN42_001085"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1462169.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVIYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDGKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16053..16541
                     /gene="purE"
                     /locus_tag="VYN42_001086"
     CDS             16053..16541
                     /gene="purE"
                     /locus_tag="VYN42_001086"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1462170.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAAIFALRLLSVEDKSIADALANFAEEQGKIAEESTNE
                     LI"
     gene            16528..17619
                     /gene="purK"
                     /locus_tag="VYN42_001087"
     CDS             16528..17619
                     /gene="purK"
                     /locus_tag="VYN42_001087"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1462171.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLAERCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17629..17856
                     /locus_tag="VYN42_001088"
     CDS             17629..17856
                     /locus_tag="VYN42_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1462172.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17919..19217
                     /gene="purB"
                     /locus_tag="VYN42_001089"
     CDS             17919..19217
                     /gene="purB"
                     /locus_tag="VYN42_001089"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1462173.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19272..23210)
                     /gene="strH"
                     /locus_tag="VYN42_001090"
     CDS             complement(19272..23210)
                     /gene="strH"
                     /locus_tag="VYN42_001090"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1462174.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYDSDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLLTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPRQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
BASE COUNT         6307 a         4651 c         5565 g         6790 t
ORIGIN      
        1 ctctctttct gattacatta ttttttgata agaataagag gaactttgga gatattcttt
       61 tatctaaaaa tataacctta agttttagca ttttactttg ttatttattt aatccatcgg
      121 atataaagtt tgcctatttc agcgtattga cagtattact aattgggata acaaattatg
      181 cgagatttaa aaatttaaga ttgacagtag tgttttctgt accattttta tttaatgcta
      241 taatgtctat tataaatagt ttttagaaat actaaaattt ttttctttac ttaataatga
      301 tatgaaatca tttcggtttt gttaacttgt aattcttata ttttctaggt agaacgtttg
      361 ttctgcctat ttttttatcc aaaaagtgca gttgggaggg agataggctc atttgggaag
      421 gaagtccagt ttttgtttag tgattggggt aagatagttg ttatcagatg agtttatact
      481 cttcgaaaat caaattcaaa ccacgtcaac gtcgccttgc cgtatatatg tgactgactt
      541 cgtcagtcct atctacaacc tcaaaacagt gttttgagca gcctgcggct agtttcctag
      601 tttgctcttt gattttcatt gagtattagg gaaaaggaga tgaatatgaa atttgggaaa
      661 cgtcactatc gtccgcaagt ggatcagatg gactgcggtg tagcttcatt agccatggtt
      721 tttggctact atggtagtta ttattttttg gctcacttgc gagaattggc taagacgacc
      781 atggatggga cgacggcttt gggcttggtc aaggtggcag aggagattgg ttttgagacg
      841 cgagccatta aggcggatat gacgcttttt gacttgccgg atttgacttt tccttttgtt
      901 gcccatgtgc ttaaggaagg gaaattgctc cactactatg tggtgactgg gcaggataag
      961 gatagcattc atattgccga tccagatccc ggggtgaaat tgaccaaact gccacgtgag
     1021 cgttttgagg aagaatggac aggagtgact ctttttatgg cacctagtcc agactataag
     1081 cctcataagg aacaaaaaaa tggtctgctc tcttttatcc ctatattagt gaagcagcgt
     1141 ggcttgattg ccaatatcgt tttggcaaca ctcttggtaa ccgtgattaa cattgtgggt
     1201 tcttattatc tgcagtctat cattgatacc tatgtgccag atcagatgcg ttcgacacta
     1261 gggattattt ctattgggct agtcatcgtc tacatcctcc agcaaatctt gtcttacgct
     1321 caggagtatc tcttgcttgt tttggggcaa cgcttgtcga ttgacgtgat tttgtcctat
     1381 atcaagcatg tttttcacct ccctatgtcc ttctttgcga cacgcaggac aggggagatc
     1441 gtgtctcgtt ttacagatgc taacagtatc atcgatgcgc tggcttcgac catcctttcg
     1501 attttcctag atgtgtcaac ggttgtcatt atttcccttg ttctattttc acaaaatacc
     1561 aatctctttt tcatgacttt attggcgctt cctatctaca cagtgattat ctttgccttt
     1621 atgaagccgt ttgaaaagat gaatcgggat accatggaag ccaatgcggt tctgtcttct
     1681 tctatcattg aggacatcaa cggtattgag actatcaagt ccttgaccag tgaaagtcag
     1741 cgttaccaaa aaattgacaa ggaatttgtg gattatctga agaaatcctt tacctatagt
     1801 cgagcagaga gtcagcaaaa ggctctgaaa aaggttgccc atctcttgct taatgtcggc
     1861 attctctgga tgggggctgt tctggtcatg gatggcaaga tgagtttggg gcagttgatt
     1921 acctataata ccttgctggt ttactttacc aatcctttgg aaaatatcat caatctgcaa
     1981 accaagcttc agacagcgca ggttgccaat aaccgtctaa atgaagtgta tctagtagct
     2041 tctgagtttg aggagaagaa aacagttgag gatttgagct tgatgaaggg agatatgacc
     2101 ttcaagcagg ttcattacaa gtatggctat ggtcgagacg tcttgtcgga tatcaattta
     2161 accgttcccc aagggtctaa ggtggctttt gtggggattt cagggtcagg taagacgact
     2221 ttggccaaga tgatggttaa tttttacgac ccaagtcaag gggagattag tctgggtggt
     2281 gtcaatctca atcagattga taaaaaagcc ctgcgccagt acatcaacta tctgcctcaa
     2341 cagccctatg tctttaacgg aacgattttg gagaatcttc ttttgggagc caaggagggg
     2401 acgacacagg aagatatctt acgggcggtc gaattggcag agattcgaga ggatatcgag
     2461 cgcatgccac tgaattatca gacagaattg acttcggatg gggcagggat ttcaggtggt
     2521 caacgtcaga gaatcgcttt ggcgcgtgct ctcttgacag atgcgccggt cttgattttg
     2581 gatgaggcga ctagcagttt ggatattttg acagagaagc ggattgtcga taatctcatt
     2641 gctttggaca agaccttgat tttcattgct caccgcttga ctattgctga gcggacagag
     2701 aaggtggttg tcttggatca gggcaagatt gtcgaagaag gaaagcatgc tgatttgctt
     2761 gcacagggag gcttttacgc ccatttggtc aatagctaga aagaggagag gatgaaacca
     2821 gaatttttag aaagtgcgga gttttataat cgtcgttacc ataatttttc cagtagtgtg
     2881 attgtaccca tggcccttct gctcgtgttt ttacttggct ttgcaactgt tgcagagaag
     2941 gagatgagtt tgtccactag agctactgtc gaacccagtc gtatccttgc aaatatccag
     3001 tcaactagca acaatcgtat tcttgtcaat catttggaag aaaataagct ggttaagaag
     3061 ggggatcttt tggttcaata ccaagaaggg gcagagggtg tccaagcgga gtcctatgcc
     3121 agtcagttgg acatgctaaa ggatcaaaaa aagcaattgg agtatctgca aaagagcctg
     3181 caagaagggg agaaccactt tccagaggag gataagtttg gctaccaagc cacctttcgc
     3241 gactacatca gtcaagcagg cagtcttagg gctagtacat cgcaacaaaa tgagaccatc
     3301 gcgtcccaga atgcagcagc tagccaaacc caagccgaaa tcggcaacct catcagtcaa
     3361 acagaggcta aaattcgcga ttaccagaca gctaagtcag ctattgaaac aggtgcttcc
     3421 ttggccggtc agaatctagc ctactctctt taccagtcct acaagtctca gggcgaagaa
     3481 aatccccaaa ctaaggttca ggcagttgca caggttgaag cacagatttc tcagttagaa
     3541 tctagtcttg ctacttaccg tgtccagtat gcaggttcag gtacccagca agcctatgcg
     3601 tcagggttaa gcagtcaatt ggaatccctt aaatcccaac atttggcaaa ggttggtcag
     3661 gaattgaccc ttctagccca gaaaatcttg gaggcagagt caggtaagaa ggtacaggga
     3721 aatcttttag acaaggggaa aattacggcg agtgaggatg gggtgcttca tcttaatcct
     3781 gagaccagtg attctagcat ggttgcagaa ggtgccctac tagcccaact ttatccatct
     3841 ttggaaagag aagggaaagc caaactcaca gcctatctaa gttcaaaaga tgtagcaaga
     3901 atcaaggtcg gtgattctgt tcgctatact acgactcatg atgccgggaa tcaacttttc
     3961 ctagattcta ctattacaag tattgatgcg acagctacta agactgagaa agggaatttc
     4021 tttaaaatcg aggcggagac taatctaact tcggagcagg ctgaaaaact taggtacggg
     4081 gtggaaggcc gcttgcagat gattacgggc aagaaaagtt atctacgtta ttatttggat
     4141 caatttttga acaaagagta atgttcgtgt ttttagagtt aaataatttt taaactgtga
     4201 gaaagattct tcttgcagtt ttttctttac aatttttaaa aaacatctgc tatttattcg
     4261 gttaaattct tgtgtttttt ggttttttgt ggtaaaatgt gctcaagtaa tacgaaaggc
     4321 gaactttaaa atgtcaaaac aattgatcta ttcgggaaaa gctaaagata tctatacaac
     4381 tgaggatgaa aatcttatta tttcaactta caaggaccag gcgactgctt tcaacggtgt
     4441 caagaaggag cagattgcag gtaagggagt cttgaataat cagatttcat cttttatttt
     4501 tgagaaatta aatgcggctg gtgtggcgac tcactttgtg gagaaacttt cagacacgga
     4561 acaactcaat aaaaaggtta agattattcc tttggaagtc gtgctccgca actatactgc
     4621 tggttccttt tcaaaacgtt ttggtgtgga tgagggaatc gccttggaga ctccgattgt
     4681 cgaattttac tacaaaaatg atgatttgga tgatccattt atcaatgatg agcatgtgaa
     4741 attcctacag attgcggatg accagcagat tgcctacttg aaggaagaaa cgcgtcgtat
     4801 caatgaacta ttgaaagtct ggtttgctga gattgggctt aaattgattg actttaagct
     4861 agagttcggt tttgacaagg atggcaagat tatcttggca gacgaatttt caccagataa
     4921 ctgccgcttg tgggatgctg atggcaacca catggataag gatgttttcc gtagaggatt
     4981 gggagaacta accgacgttt atgagattgt ttgggaaaag ttgcaggaat tgaaataatc
     5041 tgtttgcaat ggaaaacctt cgtctctcaa ctaaaaggac tcaggctgaa aaggtccccc
     5101 agaccttttc actctgtaga gaactaggtg aactaaccga tgtttacgaa attgtctggg
     5161 aaaagttgca gggtttaaaa taacaacctc aaggctgttt gggaatattg caagagctga
     5221 aataaaggaa taagaattga tggataaacg tatttttgtt gaaaaaaagg ctgattttca
     5281 ggtcaagtca gagagtttgg ttagagagct ccagcacaac ttgggactgt caagcttgaa
     5341 aagtattcgt attgtgcaag tatatgatgt atttgacttg gttgaggact tgtttgcacc
     5401 tgcagagaag cacattttct ctgagcaggt aaccgaccat gttttagatg aagtatctgt
     5461 gcaggcggat cttgctaact atgctttctt tgccattgaa agtctgccag ggcagtttga
     5521 ccagcgtgca gcttcgtcac aggaagcctt gcttttgttg ggaagttcga gtgacgtgac
     5581 agtcaacaca gcccaacttt acttggtgaa taaagatatt gatgcgactg agttggaagc
     5641 tgtcaaaaac tacctgctca atccagttga ttctcgtttc aaggatatca cgacagggat
     5701 tgccaagcag gagttttcag agtcagacaa gaccattcca aaattgactt tctttgaaag
     5761 ctatacagca gaagactttg ctcgctacaa ggccgaacaa gggatggcca tggaagtgga
     5821 tgatttgctc tttatccaag actactttaa gtcaatcggg cgcgtgccaa ctgagactga
     5881 actcaaggtt ttggacactt actggtctga ccactgccgt catacgactt ttgagacaga
     5941 gttgaaacac atcgactttt cagcttctaa atttcaaaag caattgcagt caacctatga
     6001 caagtatatt tccatgcgcg aggaattagg tcggtctgaa aaaccacaaa ccttgatgga
     6061 tatggcgact attttcggtc gttatgagcg tgctaatgga cgattggatg atatggaagt
     6121 ctctgacgaa atcaatgcct gctcagttga aattgaagtg gacgttgatg gtgtcaagga
     6181 accttggctc ctcatgttta aaaacgaaac ccacaaccat ccaacagaaa ttgagccatt
     6241 tggtggagcg gctacctgta tcggtggagc tattcgtgat ccgttgtcag gccgttccta
     6301 tgtttaccaa gccatgcgta tttcaggtgc tggtgatatt acagcaccga tttcggaaac
     6361 tcgtgctggg aaattgccac aacaagtcat ttctaaaaca gcagctcatg gttattcttc
     6421 atatggtaac cagattgggc ttgcaacaac ctacgttcgt gaatacttcc acccaggttt
     6481 tgtagctaaa cgtatggaac ttggtgccgt tgttggtgcg gctcccaagg gcaatgttgc
     6541 ccgtgaaaaa cctgaagcag gtgatgtgat catccttctc ggaggcaaaa caggtcgtga
     6601 tggtgtcggt ggtgcgacgg gctcttctaa agttcaaaca gttgagtctg tagagactgc
     6661 tggtgctgag gttcaaaaag gaaatgccat cgaagaacgc aagattcagc gcctcttccg
     6721 taatggcaat gtcactcgtc tgatcaagaa gtccaatgac tttggggcag gcggtgtctg
     6781 tgtggctatc ggtgaattgg cagacggtct tgaaatcgac ctcaacaagg tgcctcttaa
     6841 ataccagggc ttgaatggta cagaaattgc catctctgaa tcacaagaac ggatggcggt
     6901 cgtggttcgt cctgaagatg tggatacctt cgttgccgaa tgtaacaaag aaaatattga
     6961 tgctgttgtg gtggcgacag taactgaaaa accaaatctt gtcatgcact ggaatggtga
     7021 gacaatcgtt gacttggagc gtcgtttcct tgacaccaat ggtgtgcgcg tggttgtcga
     7081 tgccaaagtt gtggacaagg atgtcaaact cccagaagag cgtcaaacat ctgctgaaac
     7141 actggaatca gataccctta cggttctatc tgacctcaac catgcaagtc aaaaaggatt
     7201 acagactgtc tttgactgct ctgttggacg ctcaacggtt aatcacccac ttggtggtcg
     7261 ttaccaactc acaccaactg aggcatctgt gcagaaattg ccagttcaac acggtgtgac
     7321 tcatactgcg tcggtcattg ctcaaggttt caacccatat gtagctgaat ggtctccata
     7381 ccacggtgct gcttatgcgg ttatcgaagc aactgctcgt ttggtggctg ctggtgccaa
     7441 ctggtccaag gctcgtttct cttaccaaga atatttcgag cggatggaca agcaagcaga
     7501 gcgttttggt cagccagtag ccgcccttct aggctctatt gaagctcaga ttcaacttgg
     7561 cttgccatct atcggtggta aggactccat gtctggtacc tttgaagaat tgaccgttcc
     7621 gccaaccttg gttgcctttg gggtgacgac ggcagatagc cgtaaggtgc tctctccaga
     7681 atttaaagct gttggggaaa atatctacta catcccaggt caagccctct ctgcagagat
     7741 tgattttgac ttgattaaga aaaattttgc tcagtttgaa gccatccaag ctgaccataa
     7801 agtgacatct gcatcagctg tcaaatacgg tggtgtagtt gaaagtttgg ctcttgctac
     7861 ctttggaaac tatattggtg cagaggcgac cttgcctgaa cttaaaacag ctttgacagc
     7921 tcaattaggc ggctttgtct tcacatctcc tgaagaaatt gctggagtag agaaggttgg
     7981 acaaacgaaa gcagacttta cactgactgt caacggtgtg aagctagatg gacacaagct
     8041 tgacagtgca tttcaaggga cattggaaga agtttaccca acagaattta cccaagcgaa
     8101 agaactagaa gaagtaccag ctgtggcatc agatgttgtg attaaagcca aagaaaaggt
     8161 tgaaaaacct gtggtttaca tcccagtctt tccaggaacc aactcagaat atgattcagc
     8221 taaggccttc gaaaaagaag gtgcagaggt caatttggtg ccattcgtga ccttgaatga
     8281 agaagctatt gtcaagtcag ttgaaactat ggttgacaat atcgacaaga ctaatattct
     8341 cttctttgcc ggtggattct cggctgcgga tgaaccagat ggttcagcta agtttatcgt
     8401 caatatcctg cttaatgaaa aagtgcgtgt ggctattgat agctttatcg tccgtggtgg
     8461 cttgattatc ggtatttgta atggattcca agccttagtc aaatcgggtc tcctaccata
     8521 cggaaacttt gaagatgcta acagtactag tccaaccctc ttctacaatg atgccaacca
     8581 acacgtggcc aagatggtgg aaactcgcat tgccaatacc aactcaccat ggttggctgg
     8641 tgtgcaagtg ggcgatatcc acgctattcc tgtttcgcac ggtgaaggga agtttgtcgt
     8701 gacggctgag gaatttgcag agctccgtga caatggacaa attttcagcc aatacgttga
     8761 ctttaacggt aaaccaagta tggattctaa gtacaatccg aatggttctg tccatgccat
     8821 cgaaggaatt accagcaaga atggtcaaat catcggtaag atgggccact cagaacgtta
     8881 tgaggatggt cttttccaaa atatcccagg caataaagac cagcacctgt tcgcgtcagc
     8941 ggttaaacat ttcactggaa aataagactt acagattttc taatagatag tatcagtaat
     9001 gtaaaagtca tgtaaatcta gctcttgatg attacaaatg aaaattaggt ataaaaaatg
     9061 acatacgaag taaaatctct taatgaagaa tgtggtgttt tcggtatttg gggacatcca
     9121 gatgctgcta agttgaccta ttttggactc cacagtcttc aacaccgcgg tcaggagggg
     9181 gcaggaatcc tctccaatga tcaaggacaa ctgaagcgcc atcgtgacat ggggctttta
     9241 tcagaagttt tcagaaatcc agccaatttg gataaattga caggagctgg tgcgattggg
     9301 catgtgcgtt atgcgactgc tggcgaagct tctgttgata acatccaacc cttcctcttc
     9361 cgttttcacg atatgcagtt tggtttggct cataatggaa atctgaccaa tgcagcctct
     9421 ctcaagaaag aactggaaca aagaggagca attttcagcg cgacttcgga ctctgaaatc
     9481 ttggctcacc tcattcgtcg cagtcataat cctagcctga tgggcaaaat caaggaagcg
     9541 ctcagccttg tcaaaggtgg ttttgcctat atcttgctgt ttgaggacaa gttgattgcg
     9601 gctcttgacc ctaatggctt tcgtccgctt tctatcggga aaatggccaa cggagcggtg
     9661 gttgtttcct ctgaaacctg tgcttttgag gtcattggtg ccgagtggat ttgtgatttg
     9721 aagccaggtg agattgtgat cattgatgac gagggcattc agtatgacag ctatacagat
     9781 gatacccagt tggcgatttg ttctatggag tatatctact ttgcccgccc tgattctaat
     9841 atccacggtg tcaatgtcca tacggcacgt aagagaatgg gagcgcaatt ggcgcgagaa
     9901 tttaagcatg aggcagatat tgtagttggt gtgcccaatt cttccctaag cgcggctatg
     9961 ggatttgcgg aagaatcagg cttaccaaat gaaatgggtc tgatcaaaaa ccaatacacc
    10021 cagcgaactt ttatccaacc gactcaagaa ttgcgggagc aaggagtgcg gatgaaactg
    10081 tctgctgttt cgggtgttgt caaaggcaaa cgtgtggtca tggtggatga ttccattgta
    10141 cgtggaacaa cctctcgtcg tatcgttcag ctcttgaaag aagcgggtgc gactgaggtt
    10201 cacgttgcca ttggaagtcc tgcactagcg tatccatgtt tctacgggat tgatatccag
    10261 acccgtcagg agctgattgc agccaatcat acggtcgaag aaactcgcca aatcattggt
    10321 gcggacagtc tgacttatct ttcaattgat ggcttgattg agtcgattgg tatcgaaaca
    10381 gatgcgccga acggtggtct ctgtgtcgct tactttgacg gtgactaccc aacgcctctc
    10441 tatgattacg aagaagacta tcgtagaagt ttggaagaaa agaccagttt ttacaagtag
    10501 gcgacagatt ctccattaaa gaaaaggaaa aaacaaatga caaataaaaa tgcatatgcc
    10561 cagtcgggtg tggatgttga agcgggttat gaagttgttg aacggattaa aaagcacgtg
    10621 gcccgtacgg agcgtgcagg tgtcatggga gctcttggtg gctttggtgg tatgtttgac
    10681 ctttccaaga ctggggttaa agaacccgtc ttgatttcag ggactgacgg tgtcggaacc
    10741 aagctcatgt tggctatcaa gtacgacaag cacgatacca tcgggcagga ctgtgtggcc
    10801 atgtgtgtca acgacatcat tgctgcaggt gcggaacccc tctattttct cgactacgta
    10861 gcgacaggga agaatgaacc agctaagcta gaacaagtgg ttgctggtgt ggcagaaggt
    10921 tgtgtgcagg ctggtgctgc cctcatcggt ggggaaacgg ctgaaatgcc gggcatgtac
    10981 ggcgaagacg actatgactt ggctggtttt gcggtcggtg tggctgaaaa atctcaaatc
    11041 attgacggtt caaaggtggt agagggagat gttcttctcg gacttgcttc aagtgggatt
    11101 cactcaaatg gttactcttt ggttcgtcgt gtctttgcgg attacacagg tgaggaagtc
    11161 ctaccagaat tggaaggcaa gaaacttaag gaagttctac ttgagccgac tcgtatctat
    11221 gtcaaggctg tcttgccgct catcaaagaa gagttggtca acggcattgc ccacatcaca
    11281 ggtggtggct ttatcgaaaa tgtccctcgt atgtttgcag atgacctagc tgctgaaatt
    11341 gatgaaagca aagttccagt gcttccaatt ttcaaagccc ttgaaaaata tggtcagatt
    11401 aaacacgaag aaatgtttga aatcttcaat atgggtgtgg gactcatgtt ggcggtcagc
    11461 cctgaaaatg tagagcgtgt aaaagaattg ttggatgaag cagtctatga aattggtcgc
    11521 atcgtcaaga aagaaaacga aagtgtcatt atcaaatgaa aaaaatagcg gtttttgcct
    11581 ctggtaatgg ctcaaatttt caggtgattg ccgaagaatt tccagtggag tttgtctttt
    11641 cagaccatcg tgatgcctat gtgcttgagc gtgcaaagca gctcggcgtt ctgtcctatg
    11701 cttttgaact caaggagttt gagagcaagg cagactacga agcagccctt gtcgaactct
    11761 tggaagaaca ccagattgac ttggtttgcc tagcaggcta catgaaaatc gttggaccaa
    11821 ccttattgtc ggcttatgaa ggtcggattg tcaacattca tccagcctac ttgccagaat
    11881 ttccaggagc tcatgggatt gaggatgctt ggaatgctgg cgtgggtcag tctggtgtga
    11941 ccattcactg ggtggattcg ggtgtggata caggccaggt catcaaacag gttcgtgtgc
    12001 cacgactagc tgatgatacc attgacagat ttgaagctcg catccatgaa gcagagtaca
    12061 ggttgtatcc ggaagtagtg aaggctctat ttacagattg actttttgat gattcatatg
    12121 atatctttga ttttaaattg gagtcagtgt ttgttgaaga cggcttcaaa cggaggtatt
    12181 tgtaatgtta gaatctaaaa aaacaactcg atatgtattt tatgtctatc tgatgttatt
    12241 aacttgggga atcttattta agtttgaaac aaatcctgaa tttatagcat ttttcttagc
    12301 tccaaggtat atcaattgga ttccattttc agaaccacta atagtcgatg gaaaaattgt
    12361 ttttgctgaa atgttattta atctgatttt ctttattcca ttaggtgttt gtttcccttt
    12421 gataaaaact aatttatcta atttaagaat agtcgggaca ggtttcttga ttagtttatt
    12481 gtttgagtgc ttacagtata ttttagcaat aggtataaca gatataacgg atttgacttt
    12541 aaatacgcta ggtgtctgtg taggcttact gatttatcaa atttttataa gagtgttcaa
    12601 atcacagact agaaaatgga tcaatatctt aggtatgctt agccttggtt ttgcttatct
    12661 tgttttactg ttactgcatt taattggtgt ttaactaatg attaaaaagg agaatataat
    12721 gactaaacgc gtcttaatca gcgtctcaga caaagcgggc attgttgaat ttgcccaaga
    12781 actcaaaaaa cttggttggg agattatctc aacaggtgga actaaggttg cccttgataa
    12841 tgctggggtg gataccattg ctatcgatga tgtgactggt ttcccagaaa tgatggacgg
    12901 tcgtgtgaag accctccacc caaatatcca cggagggctt ctcgctcgtc gtgacttgga
    12961 tagccacttg gaagcggcta aggacaacaa gattgagctc attgaccttg tggtggtcaa
    13021 cctttaccca tttaaggaaa ctatccttaa accagatgtg acttatgctg atgcagttga
    13081 aaatatcgat attggtgggc catctatgct tcgttcagca gcgaaaaatc atgccagtgt
    13141 tacagttgtg gtagatcctg ctgactacgc tgtggttttg gatgaattgg cagcaaacgg
    13201 cgaaacctct tatgaaactc gccaacgttt agcagccaaa gtatttcgtc acacagcggc
    13261 ttatgacgcc ttgattgcag aatacttcac agctcaagtg ggtgaaagca agcctgaaaa
    13321 actcactttg acttatgacc tcaagcaacc aatgcgttac ggtgagaatc ctcaacaaga
    13381 cgcggacttt taccagaaag ctttgcctac agactactcc attgcttcag ccaaacagct
    13441 caacgggaaa gaattgtcat ttaataatat ccgtgatgca gatgctgcta tccgtatcat
    13501 ccgtgacttc aaagatagtc caaccgttgt ggctctcaaa cacatgaatc catgtggaat
    13561 tggtcaagct gatgacatcg agactgcttg ggactacgct tatgagtctg acccagtgtc
    13621 tatctttggt gggattgtcg tcctcaaccg tgaggtggat gctgcgacag ctgagaagat
    13681 gcacggcgtt ttcctcgaaa tcatcattgc accaagctat acggatgaag cgctagccat
    13741 tttgatcaat aaaaagaaaa acttgcgtat ccttgccttg ccatttaatg ctcaagaggc
    13801 tagcgaagtg gaagcagaat acacaggtgt agtcggtgga cttctcgtgc aaaatcaaga
    13861 cgtggtcaag gaaagcccag ctgactggca agtggtgacc aaacgtcagc caaccgagac
    13921 agaagcgact gctcttgagt tcgcttggaa ggctatcaag tacgtcaaat caaatggtat
    13981 tatcgtgacc aacgaccaca tgacacttgg tgttggtcca ggtcaaacca accgtgtggc
    14041 ttctgttcgc cttgccattg accaagccaa agatcgtctg gacggggcgg tccttgcttc
    14101 agatgccttc ttcccatttg cggataacgt ggaagaaatc gccaaagcag gaattaaggc
    14161 catcatccag cctggtggct ctgtccgtga ccaagaatcc atcgaagcag cggataaata
    14221 cggcttgact atggtcttta caggtgtgag acattttaga cattaagaag ataaaaggga
    14281 agaaaacagt ttctttcctt ttttggctta aaatgctaac tgaaacaaga ttaaaacgaa
    14341 cttttttgat ataatgttgg taaataattc gcaaaagagg ttgaggaatg aaactgcttg
    14401 ttgtcggttc tggtggtcgt gagcatgcga ttgctaaaaa gttacttgaa tcaaaagacg
    14461 tggaaaaagt ctttgtagct cctgggaatg atgggatgac tctggatggt ttggaattgg
    14521 taaatatctc tatttccgaa cattctaaat tgattgactt cgcaaagacc aatgatgttg
    14581 cttggacctt tatcggtcca gatgatgccc ttgctgctgg tatcgtggat gattttaacc
    14641 aagctgggct taaggccttt ggtccgacta gggctgcagc ggagctggag tggtccaagg
    14701 attttgccaa ggaaatcatg gtcaaatatg gtgtttcgac agcagcctat ggcacatttt
    14761 cagatttcga ggaagcaaag gcctatatcg aaaagcatgg tgcgcctatc gtagtcaagg
    14821 cggatggctt ggcgcttggg aagggtgtcg tcgttgctga gacggttgag caagcggtcg
    14881 aagccgctca tgagatgctt ttggacaata aatttggtga ctcaggtgcg cgcgtggtta
    14941 ttgaggaatt ccttgaagga gaggaatttt cactctttgc ctttgtcaat ggtgataagt
    15001 tctacatcat gccaacggct caggaccaca aacgtgccta cgatggcgac aaagggccta
    15061 acacgggtgg tatgggtgcc tatgcgccag ttccacactt accacagagt gtagttgata
    15121 cagcggttga caccattgtc aagccagttc tagaagggat gattaaagaa ggtcgccctt
    15181 atctaggtgt catttacgca ggacttatct tgacagcaga cgggccgaag gtcatcgagt
    15241 tcaactctcg atttggagat cctgaaactc agattatatt gcctcgtttg acatctgatt
    15301 ttgcgcaaaa tatcacggat attctggatg gcaaggagcc aaatatcatg tggacggaca
    15361 agggtgtgac tctgggtgtg gttgtcgcat ccaagggcta cccgctagac tatgaaaggg
    15421 gcgttgagtt gccagccaag acagaaggcg atgtcatcac ctactatgca ggggctaagt
    15481 ttgcggaaaa tagcagagca ctgctctcaa acggcggacg agtttatatg ctcgttacca
    15541 cagcagatac cgtcaaagaa gcccaagcca gcatctacca agaactatcc caacaaaaaa
    15601 tagaaggact cttctaccga acagatatcg gaagcaaggc aattaagtaa agatataaga
    15661 ataacgcgcc gtagtcgcca aacacgataa tggtcgtcgt ggtgaaaaga ccagaacagt
    15721 gaatgttctg gtcaggggga aacttggaga ccgtaggctc aaagtttagg aatgaaaccg
    15781 aaggtttgct tccgcctcta tcacctaaga ccattatcaa aaagaaaaat aaaaattcac
    15841 aaaatacgtt aatgatcgta tggtttgcga gcgttagcga gctaatatag aacaatcacc
    15901 gccgttgtga aagaacgatt ggatgataat ccaatcgttc agggaaattg gaagaccttg
    15961 ggtttccaat ttaggcatga gacacctttg gtggctgctg ccgtccctca caagctaagg
    16021 tgattgttga aaaagaggaa aaaggagaag aaatgaaacc agtaatttcc atcatcatgg
    16081 gctcaaaatc cgactgggca accatgcaaa aaacagcaga agtcctagac cgcttcggtg
    16141 tagcctacga aaagaaagtt gtttccgcac accgtacacc agacctcatg ttcaaacatg
    16201 cagaagaagc ccgtagtcgt ggcatcaaga tcatcatcgc aggtgctggt ggcgcagcgc
    16261 atttgccagg catggtagct gccaaaacaa cccttccagt cattggtgtg ccagtcaagt
    16321 ctcgtgctct tagtggagtg gattcactct attctatcgt tcagatgccg ggtggggtgc
    16381 ctgttgcgac catggctatc ggtgaagctg gagcgactaa cgcagctatc tttgccctcc
    16441 gtctcctctc tgtagaagat aagtccattg cggatgcact tgccaacttt gctgaagaac
    16501 aaggaaaaat cgcagaggag tctaccaatg agctcatcta aaacaatcgg aattatcggt
    16561 ggcggtcagc tgggtcagat gatggccatt tctgctatct acatgggtca taaggttatc
    16621 gcgttggatc ctgcagcgga ttgcccagcc tctcgtgtgg cggaaatcat tgtggcgcct
    16681 tataacgatg tggatgccct tcgtcagcta gctgagcgtt gcgatgtcct gacttatgaa
    16741 tttgaaaatg tcgacgctga cggtttggat gccgttatca aggatggaca actccctcaa
    16801 ggaacagatc tgctccgcat ttcgcaaaat cgtatttttg aaaaggactt tttgtcaaac
    16861 aaggctcaag tcactgtggc accctacaag gtcgtgactt ctagcctaga cttggcagat
    16921 atcgacttgt cgaaaaacta tgtcctcaag actgcgactg gtggctacga tggtcatgga
    16981 caaaaggtta ttcgttcaga agcagacttg gaagcagcct atgcgctagc agactcagca
    17041 gactgcgtct tggaagaatt tgtcaacttt gaccttgaga tttctgtcat cgtgtcagga
    17101 aatggcaagg aggtgacgtt tttcccagtt caggaaaata tccaccgcaa caatatcctg
    17161 tctaagacca tcgtaccagc ccgcatttct gaaagtctag cagacaaggc taaagctatg
    17221 gcagtgcgaa tcgcagaaca actcaacttg tctggaactc tctgtgtgga aatgtttgcg
    17281 actgatgatg acgttattgt caatgaaatc gccccacgac cacataactc tgggcactat
    17341 tctattgaag cctgtgattt ctctcagttt gacacccata ttctgggtgt tctcggagca
    17401 ccattaccag tcatcaaact ccatgcgcca gccgttatgc ttaatgtcct cggtcagcat
    17461 gtcgaggctg ctgagcaata tgtgacagaa aattcaagcg cccacctcca catgtatggt
    17521 aaaatagaag caaagcataa tcgtaagatg ggacatgtga ccttgtttag tgatgtaccg
    17581 gatagtgtgg atgagcttgg ggaagggatt gatttttagg acaagtctat gatacaaatt
    17641 atcgttaata catttattga aaaggataag actggagcag ttgttgaagt gttgtatgcc
    17701 agtgctgacc aagataaggt acaagctaaa tatgaagaac tagctgcaca ataccccgaa
    17761 aattatttag ctatctatga tgtaccgctg gatacggatt tgaatacact agatcattac
    17821 ccgtctgtgt ttattgaaaa agaggagttt gagtagaaat cttggtttac ctagatagct
    17881 tattcccaac agcttaagaa gaaaggaaaa attaacacat gatcaaccgt tactctcgcc
    17941 ctgagatggc gaatatttgg agtgaagaaa ataaataccg tgcttggctt gaggtggaaa
    18001 tcctctctga cgaggcatgg gctgagttgg gggaaatccc taaggaagat gtggctttga
    18061 ttcgcaagaa ggcggacttt gacatcgacc gtattttgga aattgagcag gagacgcgcc
    18121 acgatgtggt ggctttcacg cgtgcggttt ctgagactct tggtgaagag cgcaagtggg
    18181 ttcactatgg gttaacttct accgacgtgg tggatactgc ttatggttac ctctacaagc
    18241 aggccaacga catcatccgt cgtgaccttg aaaacttcac taatatcatc gctgacaagg
    18301 ccaaggagca caagttcacc atcatgatgg ggcgtactca tggtgtgcac gctgagccga
    18361 caacctttgg tcttaaattg gcaacttggt acagcgaaat gaaacgcaat atcgagcgtt
    18421 tcgagcatgc agctgctggt gtagaagctg gtaagatttc tggtgcggtt gggaactttg
    18481 ccaatatccc accatttgta gaggagtatg tctgcgataa acttggcatc cgtgcccaag
    18541 aaatctctac acaagtcctt cctcgtgacc ttcacgctga gtactttgcg gttcttgcca
    18601 gcattgcgac ttcaatcgaa cgtatggcga ctgagattcg tggtctacaa aaatctgagc
    18661 aacgcgaagt agaagagttc tttgctaaag ggcaaaaagg gtcttcagca atgcctcaca
    18721 aacgcaaccc aatcggttct gaaaatatga ctggtctggc gcgtgtcatt cgtggtcaca
    18781 tgattacggc ttatgaaaac gtcgctctct ggcacgaacg cgatatttct cactcatcag
    18841 ctgagcgtat catcacacca gatacgacca ttttgattga ctacatgctc aaccgttttg
    18901 gaaatatcgt caagaacttg acagtcttcc cagaaaatat gatccgaaac atgaactcga
    18961 cttttggtct tatctttagc caacgggcta tgttgacatt gattgaaaaa ggcatgaccc
    19021 gtgagcaagc ctatgacttg gtgcaaccaa aaacagccta ctcttgggac aaccaagtag
    19081 actttaaacc acttcttgag gcagattcag aagtaacatc acgtctcact caagaagaaa
    19141 tcgatgaaat cttcaaccca gtttattaca ccaaacgagt ggatgatatc tttgaacgtc
    19201 ttggactagg tgattaatta aaaaataaac agcgagcttc aatctcgctg tttatttttt
    19261 atcgaaaaga cttagtcttc ttttctttta gtgagtccat aggctgctag tgtggacatg
    19321 agtcctgcga ctactagtcc tgcagaatcg tgagttcctg tttcaggaag ttttttctct
    19381 gttaccacag gagctggatc ttgaggaaga gctttgcttt cctcagcagg agcagttgat
    19441 ggagctggtt gtcttgggat ttctagtttt ggtttttctt cagcaatagc ggcttgtccg
    19501 ttttcatcgc ctacatgtgt taccatagtt ccgacttcga ctatttgagt aacggcttcc
    19561 tgtgctacga cactatttac aagtgttttc acttccttac catcggcaga agtgctcaca
    19621 gagtagaagt tgctacgatg tccattgacg cccttagtaa tgacttgtgt ttttcctttg
    19681 agtaagagtg gattttcacg agtcactgtg gtaaatggaa tttcttcttt ttggatatcc
    19741 agtctaggtt ttacctcagt agttggtgca agaccacttt catcaccctt gtgagttaca
    19801 ggagcgccaa cttcaaccac ttggtttata acttctttgg ttacctggct atcaaggact
    19861 gtttctgttg tttttccatt ttcagtgagt acagagatgt aatgagttcg ttcacctttg
    19921 actcctgctg tgataatatt ttcctgacca gctgggaggt taggattttc tttcttgata
    19981 acttcaaatg gaatttcttc agttcttgtg atgagttctg gtctggtttc aacattggca
    20041 gccacttcat tttcatctag gcttcctgaa tgagttgcag ctggtttgag gccttgaaga
    20101 gcggctttta ggttggctac aagtgtgtca agctcagctt gtttattacg gttgaggttg
    20161 taatttagag ctgttttagc tgcgtcaagg gcctcaagac tttctttact atatccttct
    20221 aagtttgtag gaattttagc taattcttcg cggagagcat tataattagc acggaagtag
    20281 tctttgttgt ggtctgcaaa ggcagtcatg agttcaaaga tttcctcttc cttgtattca
    20341 gcgcttggtc tatctgccca gattgaaagc atacttccga ctgttagaag atctacttca
    20401 ggatatttgg tagaagctag ttgattgaat ggtgtttttc cagtattctc aatagctttc
    20461 ttgaggaaac caccaccatc ttctggtttt tgaccaagaa tgtagtacca gtcaccgttg
    20521 gtattcaaga atttatagcc tttgcttgct aggtattgag gtgatgcgag gttatatccc
    20581 caccagcctt tagaccagta agaaatcaag acatctttgt caaactgaac atcgtccttg
    20641 tcttcatagt agaagccatc gttgaaggcc attggttgaa gccctctttc tttggccata
    20701 gctgcgaggg tgttggcata ttcggcaaat ttgccataga gttgatacca cttgaggtag
    20761 taccagcctt gggcactagt cgcatcgttg gcgtattcgt cagtaccaaa gttgaaaatc
    20821 tttgttttac ctgcaaagaa gtccatgtat ttaccgatga gggcttttac aaagttcatc
    20881 gcttcttcgt ttttcaagtc catagttgtt tttgaaactt tatcaaagtg ggcttgagga
    20941 tttttaatac ctaatttttc catggcaacc agcatagcat ccatgtgacc tggactgtta
    21001 atagctggga tgagaccgat gtccttagat ttagcgtatt caattagctc tgttacttct
    21061 gcctgtgtta gtgcagtacc gtttggatcg tcgtagtaag ctttagttcc ttcgataata
    21121 gcttttttaa cgtcatcact agcataggtt tttccgttgg cagtaatggt catatcatcg
    21181 agtagaaagc gaagtccgtc atttcctaga aggagatgga catcagaata tccgagctca
    21241 ctggccttgt ctacgatgcg tttgagctgg ttcagagtaa agtatttgcg tccagcatcg
    21301 attgagatta ccttgttttt ggcaagtttt tcaacctcac gtttagcttc ttcttctttt
    21361 tgagcttcag gcgtgagggt caagttgttg acagtttctt gaagtttagc aatggcttga
    21421 tcaatcgtat cttgttgggc acggctaagg ttgctatcga gagagcgaat agctttttca
    21481 gcttctttta cggccgtgac gctttctgca gtataacggt tcaggtcttt tggtacctcg
    21541 ttaagtgctt gctctgcaga ttcataatca gctgcgaagt attcagcgtt ggcatttgca
    21601 aaatgacgca tgagtttgaa gaggcgtgat ggtgaataac gtgcagatgg agtgtcagcc
    21661 caagcagcta ccataccacc gatgattggg atatcagctc cttctgtttt tggtacagaa
    21721 gtgattggtg tgtttttaat accattgagc ccctgatcga gattgtacca gccttggcca
    21781 tcagcgtttc gtccaagaac gtagtaccaa gcatcattgg tattaaggat ttggtgacct
    21841 ttttcagcta gtagtttaga agaagcgaca tcgtagcctc cccaaccacc agtccacata
    21901 gaaacgatga tgtctttgtc aaaactacca aagcttgtgt cgctattgta gtagataccg
    21961 tcgttaaagg ccattggttt gagaccgtgc gattttacaa tacgagcgag gtcattggcg
    22021 taggcaataa atttttcata gccttttaca gggtagcctt cgtttggata gtatttatca
    22081 gcttgaagca cactccaacc tttagcatct gtcgcatcat tggcatattc atcaagtccg
    22141 atgttgaaga tttcagtctt tttcgcgaaa taagcagcat acttgtcgat aagggctttt
    22201 gtaaaagcga cagcttgttc gttgtcaaga tcgacagtac gggctgattc cttcccaaaa
    22261 tagctaaagt tagggttttg gattcccaat tctttcatgg cattgagaat cgcatccatg
    22321 tgaccaggac tatttactgt cggaatgaga ccgatacctt tatctttggc atagttaatc
    22381 agatctgtca tttgactttc tgttaagtga ttgccgtttg gatcgttgta ataatcattt
    22441 gtaccttttt caatggcgcg tttgacatcg tcactgtcat aggtcttgcc gttagctgtg
    22501 atgctcatat cgtccaacat gaaacggagt ccatcatttc cgactaatag gtgtaaatca
    22561 gtgtagccat aatgtttcgc tttatcgatg atttccttga gctgttctgg tgagaaatat
    22621 ttacgtccag catcaataga aacaattttc tttttcgcta gtttttcatt tacagttgca
    22681 gcacgttcct ttcctgcctc tgtttccggt ttgtcagcct ctgctttcgc ttcatctttt
    22741 ttagctggtt tatccttgtc agtcttgtct gtatttgact ctttagaatc aacctctttc
    22801 gcttcttcct ttttagggct agcttcttct gcctttttat tagcagtttc tttttcagca
    22861 gaagttggag ttaccacttc tgctttatca ctaggagttg aactaacttc ctcttgtggt
    22921 ttttcttctg tttttggaag actagctacc ttatcagtag ctggagtttc tgtttctaca
    22981 gtttttggag cttctggttg aagctctgct ttaggtgttt cctcagtccg attttcggat
    23041 gattgagggg aatcagaaac cgtatggatg gtcggttggt tttctgtagt agtaggagta
    23101 actccatcgg ctgcaacagt ctgtgcttgg aaggcaaatc caattagaac agaagctgct
    23161 cctacagcgt atttacgaat agaaaaacgc tgttgttttt catgtttcat tgcaaaacct
    23221 cctgattgca ttgttatatt gatagcgatt atataaatca acgcctttat tttatttctt
    23281 atattaacga gagtcaagag gagatgacaa aaa
//
LOCUS       DAVLUM010000031        22984 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLUM010000031 DAVLUM010000000
VERSION     DAVLUM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.031"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..89)
                     /locus_tag="VYN42_001091"
     CDS             complement(<1..89)
                     /locus_tag="VYN42_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1462175.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGV"
     gene            complement(181..1512)
                     /locus_tag="VYN42_001092"
     CDS             complement(181..1512)
                     /locus_tag="VYN42_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1462176.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(1534..3045)
                     /locus_tag="VYN42_001093"
     CDS             complement(1534..3045)
                     /locus_tag="VYN42_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1462177.1"
                     /translation="MSEKAKKGFKMPSSQTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALAIGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(3254..4201)
                     /gene="arcC"
                     /locus_tag="VYN42_001094"
     CDS             complement(3254..4201)
                     /gene="arcC"
                     /locus_tag="VYN42_001094"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1462178.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(4366..5382)
                     /gene="argF"
                     /locus_tag="VYN42_001095"
     CDS             complement(4366..5382)
                     /gene="argF"
                     /locus_tag="VYN42_001095"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1462179.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(5440..6669)
                     /gene="arcA"
                     /locus_tag="VYN42_001096"
     CDS             complement(5440..6669)
                     /gene="arcA"
                     /locus_tag="VYN42_001096"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1462180.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            7425..9104
                     /locus_tag="VYN42_001097"
     CDS             7425..9104
                     /locus_tag="VYN42_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1462181.1"
                     /translation="MKKIKPHRPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPTQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(9144..11228)
                     /locus_tag="VYN42_001098"
     CDS             complement(9144..11228)
                     /locus_tag="VYN42_001098"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1462182.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            11399..12679
                     /locus_tag="VYN42_001099"
     CDS             11399..12679
                     /locus_tag="VYN42_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1462183.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            12770..15415
                     /locus_tag="VYN42_001100"
     CDS             12770..15415
                     /locus_tag="VYN42_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1462184.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            15499..16368
                     /locus_tag="VYN42_001101"
     CDS             15499..16368
                     /locus_tag="VYN42_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1462185.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALISYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            16362..18242
                     /locus_tag="VYN42_001102"
     CDS             16362..18242
                     /locus_tag="VYN42_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1462186.1"
                     /translation="MVRFIGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            18568..18783
                     /locus_tag="VYN42_001103"
     CDS             18568..18783
                     /locus_tag="VYN42_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462187.1"
                     /translation="MILWSFDFVNDHAHAFFMDNVEWSHADSYFLSFVSDDVEERYIE
                     NVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(18946..19182)
                     /locus_tag="VYN42_001104"
     CDS             complement(18946..19182)
                     /locus_tag="VYN42_001104"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1462188.1"
                     /translation="MKIYPQAQTPRKSSKLKPLTAEDKAYNHALSKERSKVENIFAKV
                     KTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(19189..19335)
                     /locus_tag="VYN42_001105"
     CDS             complement(19189..19335)
                     /locus_tag="VYN42_001105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1462189.1"
                     /translation="MKAQAIVTSQGRIVSLDIAVNYCHDMKLFKMSRRNIGQAGKILA
                     DSGY"
     gene            complement(19708..19884)
                     /locus_tag="VYN42_001106"
                     /pseudo
     CDS             complement(19708..19884)
                     /locus_tag="VYN42_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            20219..21904
                     /locus_tag="VYN42_001107"
     CDS             20219..21904
                     /locus_tag="VYN42_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEV1462190.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKD
                     KGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(22384..22533)
                     /gene="rpmG"
                     /locus_tag="VYN42_001108"
     CDS             complement(22384..22533)
                     /gene="rpmG"
                     /locus_tag="VYN42_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1462191.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(22549..22731)
                     /gene="rpmF"
                     /locus_tag="VYN42_001109"
     CDS             complement(22549..22731)
                     /gene="rpmF"
                     /locus_tag="VYN42_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1462192.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
BASE COUNT         6738 a         4529 c         5004 g         6713 t
ORIGIN      
        1 acaccaaatc tttttgaaag ctgtttgaag ctttgtcctt gctttcttag ttcatagatc
       61 tgaactttat cttcataact caatttcata ataaaacacc ccaaaagtta gatttattct
      121 gtctaacttt tggggtgcag ttcattttgc gggatttttt tggtagaaac agttgcctga
      181 ttaagttgca agtcgataga cggcttcggc ataaatatcc atagcacggt acaaatcttc
      241 tagaacggca cattcatttg cctgatgttc tgtctgcttc gctcctggga ataaggcgcc
      301 gaaggctaca caatttggca tggtgcgagc aaaagtggca ccaccggatg aaatagcagg
      361 actgttatcg ccagtctttt cttggtagat ttgcatcagt gtgctaacga gtttactgtc
      421 ttttgcgacg tatagaggcg ctagatagtc aaactcttcg tagcggagtt ggtagttttg
      481 tgcacatctt gtaagcaact ctactagttc ttccttatca gctaagacag gagtccgaat
      541 gtcaatacgg atttcagaac gttcatgatt gatcatgaga cctgcgacat taaaggatag
      601 gtgaccagaa ggttcatctg ctatatcacc aaagatttgt cttcctgtgc cgtcttgacc
      661 tgcttgtgtt gcaagaaagc tgagagcagg gtgttcttgg agaggagcaa gaatggtagc
      721 tagtcggatg acagcattga taccttgact agcatcctta gcatgctttg gcactccgag
      781 aaccgttacg gtttgttcag tggattggta atcataacca gcttctttga gatcgttaca
      841 aacctgttca tagaggggac cttggtagtt ggccttgtct ggtacaacgt taaaggcgcc
      901 tcctacttca agctctagtt gatccgatcc agggccatga agtttgacct gtagaagccc
      961 tttttcagca taggtcagag gaaaagatga gtcaggtgca aagcccatac tggcctgttc
     1021 ttcgatggta ttgtagcgtg ccatgcagcg ccagagggtt tcctcatcgg taccaaagat
     1081 aaagcgtacg cgctttttga actgaatacc ttggtccagc aagcttttta ctgcatagag
     1141 agctgcgagc gaagggcctt tatcatcttg gacaccacgt ccgaataccc agccgtcttt
     1201 gatagttgct tcaaatggcg gtgtctgcca atctgcttca tcacctgatg gaacaacatc
     1261 caaatgacag agaatggcca gaagctctgc tccctgaccg atttctgcat atccgtaata
     1321 acctttaggg tcaagatagg tagtgaaacc tatgtctcga caaatctcta aagttttttc
     1381 taggacatct tggattgctt gtccaaaagg tgttccattt tctccttcat tgagtactga
     1441 aggataggaa atcaaggttt ttaatgatat aagaaattca tctttaactt gatttgttat
     1501 atctattttc atggaatcac ctcactcact attttatagg aatggaagga aggttccaag
     1561 gagaagaagg gcgatggtca ctacaataat agcgactacg agtttgccca tgaatttcca
     1621 ccaagtacca atgttgatac gtccaattgc aagagctccc atcacaatac cagatgttgg
     1681 tgcaatcaag ttcaagacac ctgaagcaga ttggtaagca gtgataatca agctaggacg
     1741 gacatttaca aattctccaa gtggagccat gatacccata gttgcgctgg caagaccaga
     1801 tgaagatggg atcaagaatg acataggtag atagaagata taagttacaa cgataaagac
     1861 ttgtgaagat agaccgctca agccttcttt accccagttg aggattgtat cggtaatcat
     1921 accgtcgttc atgataactt gaataccacg agcaatcgct acgatcaagg caacactgag
     1981 caagtcagca gcaccattca tgaaggaaga gataatctta tcttctttaa gaccataaat
     2041 aacaccaatc aggataccca taaaggcaaa gagcattgcg ccttctggga agtaccaagt
     2101 acctagtgca gaagtagatg aaccgacaat attaccaata actggaagac cagtcaacca
     2161 agtattaaag tcatcaaaaa tggtaacgcc aaggtctgtc catggaatga agctcaatac
     2221 catcaagatg aatgtcaaca caaataagaa gagaactgat ttttgtttgc tgctaagtgt
     2281 agattctaca gatgaagatt cttctacgtt aaagtgtttc aaatcttctt tgcgagtact
     2341 ataaaccagt gacttagtcg gatctttttg aatcttatcc gcataacggt aaacaaacca
     2401 agtactaaga gcagtcaagg taacccagaa gatcagacga agtacgatac cgtcccctgt
     2461 accaactccc gcagtcgctg aagcaatacc tgtcgcaaat ggattcagag tagatgccaa
     2521 acagccgatt tgagaaccga gcaaaataat tgcaacacca gtcaggctat caaaaccaac
     2581 ggccatcata actggcacaa ggagtggata gaaggccatt gtttcttcac ccataccata
     2641 agttgtacca ccgagggcaa acaaaggcat cagtaccaaa attaacattt tttcgcggcc
     2701 cttatacttc ttcacgatag aggcaatccc tacgtcaaga gcaccagttt tgttgacaat
     2761 gccaaggaaa ccaccaacca taaggatgaa gaaggctaca tcaatcgctg cgctcgtttc
     2821 tttaatgagc gaaccttcct ctggatgagt acctagcata gcccgaatcg gtgccatgag
     2881 gacatcccaa atcccttgtg gattttgagg ctgagtctcg taaatacctt ctataaaggc
     2941 ccccgcaggg ataaaccaag ttagcactgc cataatagca atgattatca ataatacggt
     3001 ttgagatgaa ggcatcttaa accctttttt agctttttca ctcatttgtt tttcctcctg
     3061 atgtctaaca aagtgtaaaa aaccaactac tttcttaaat aaacattcaa gaaaacgctt
     3121 tctatttata tttgttttac catattaaag tctaaaacta gtatcttttg aaatattgta
     3181 catgttttca agaataattt ctaatttgat ataaagatac tagaaataga atacatctta
     3241 ttagtaaaac aacttatcct ttttcaataa ttgttccgct ttcagattca atcaaggcgc
     3301 ctagattttc aagggaagta ataactgctt ttccttctgg acgaccattg acaaaagcga
     3361 tagctgcttc tacttttgga agcatgctac ctggtgcaaa ctgatcttgt ttgatatatt
     3421 cttccagctg ggcaacattc acatgttcca atttttcctg gtttggcttg ttgtagttaa
     3481 caaatacata atctacacct gtcaaaacga tgaagaggtc tgcatcaacc aattctgcca
     3541 aacgttggga agcgaagtct ttatcaataa ccgcttcgac accagtcaaa tgtccattgt
     3601 tttctttgac gacgggaata ccgccaccac ctgcagctac gacgacttga ccattattta
     3661 aaagagtacg gatggtttca atttctttga tgtcaacagg ttttggtgag gcaacgacct
     3721 tacgccagcc acggccagca tcttccttga aagtcgctcc gctcttttcg gcttctgctt
     3781 ttgcttcttc ttctgaatag aaaggaccga ttggtttact caagttaaca aaagctggat
     3841 catttttatc tacgacaact tgcgttacaa cagaggcaac atttttttcg atgccttcat
     3901 ccaagagagc attttgcaaa gcatttttca accagaaacc gatgctacct tctgtcatag
     3961 cgacaagtga gtcgagtggg aaggcagggt tcttttcaga gtctgatgcc aaatgttgga
     4021 gcaagagatt cccaacttga ggtccattac cgtgagtgat aatcagatca tctccatttt
     4081 taatcaattt tacaagatgc ttagctgttt caactaaagc ttcttgttga gcctttgctg
     4141 atgggtcaga agaaagaatc gcatttcctc ccaaagctac tacaatttta cgatttgcca
     4201 taaattctcc tttatcacac tcaatagaat gcgtttagat ttcaatttaa tgatttttca
     4261 catattttat aagaaataat agattaccat tacataaaag aggaccggac taaagctatt
     4321 agtcgcagcc ctcatagctg ttggtagacg gtttattatc taaaattata ctttaggaat
     4381 ataaaggtta ccaagtgtag cagccataac agctttgata gtgtgcatac ggttttctgc
     4441 ttgatcgaag tggcgagcgt acttgctgcg gaagacttcg tctgttactt ccatttcttc
     4501 tacaccaaat ttttcagcaa cgtctttacc ataaacagtg tgagtatcgt ggaatgctgg
     4561 caagcagtgt aggaagatca agttttcatt gcctgctttt ttaactaagt ccatattgac
     4621 ttggtaaggt ttaagaagag ctacacgttc tgcgaatttg tcttcttcac ccattgatac
     4681 ccaaacgtct gtgtaaagaa cgtctgcatc tttaactgct tcatcagcat cttcagtgat
     4741 gagaacatgt gcgccacttt ctttagcaaa tccttctgcc aattcaacga tttctttttc
     4801 tgggaagagt tcttttggtg agaagatgtg aacattgaca ccaaggatag cacctgttac
     4861 gagcaagctg ttggcaacgt tgttacgtcc atcaccacag tataccaatg tcaagccttc
     4921 caagcgaccg aagttttctt gaacagtcaa gtagtcagcg agcatttgag ttgggtgcca
     4981 ttcgtcagtt agaccgttcc atactggaac gcctgagaat tctgccaatt cttcaaccat
     5041 acgttggctg aatccgcgga attcaatccc gtcaaacata cgtcccaata ctttagcagt
     5101 atcttcagta gattcttttt tacccaactg aatatcattt gctccgaggt attctgggtg
     5161 agcaccaagg tcgatagccg cagttgtaaa ggctgcacga gtacgagtag atgttttttc
     5221 aaataggaga gcgatattct tgccagcaag gtagtggtgt tgaatattgc gttttttcaa
     5281 atctttcaag tgagctgaaa gaccaataag gtattctaac tctgcacggg taaagtcttt
     5341 ttctgctaag aagctgcgtc cttggaatac tgaatttgtc attttattat ttcctctttc
     5401 tattttttac attttctatt gacgaatgcc gaacagcgat tacacttctt cacgttcaaa
     5461 tggcatagac atacaacgag gtccaccacg gccccgaacc aattcacttc cgcgaatctt
     5521 aatcaagcga agcccgtatt cttccaaaat cttattggtc acggtattgc ggtcataaac
     5581 aactaccaca ccaggtgcga tggtcaaagt gttagaaccg tcgttccatt gttcacgcgc
     5641 agctgctacg atattgccac caccgcaacg aatcaaatga actttttcta caccaaggtt
     5701 ttgagcaaga agttcagcta agtcaccttt ctcttcaaca attttaagtt tttcgttttc
     5761 gtaagtaact gagtaaacgt gaaggtcgcc ttcgatttct gggtgaatag tgaacttgtc
     5821 atagtctacc atagtgaaga cagtatccaa gtgcatgaat ttacggttgt tagcaaattc
     5881 aaaggccaaa actttcttga agccaacatt tttcttgaag atgttgacca aaagtttttc
     5941 gatagaagct gcgtctgtac gttgagagat acctactgca aggacgtctt tagaaagaac
     6001 taactcgtct ccaccttcga tacgcgtatc ttcttcacgg ttgtagacca aatccacttt
     6061 tccgccatag attgggtggt atttgaagat atacttaccg tagagtgttt cacggttacg
     6121 agtgtctgca aacatgtggt taagcgatac ggcgtttcca attgttgcaa atgggtcgcg
     6181 agtgaaatag aggtttggca tcgggtcaat tgcaaatgga taatctgatt caactaagtc
     6241 agttagatct ttagcttcgt caggaatttc tggcaattca actttttgaa tcccagccat
     6301 tgttttttca accaattctt ggttgtcctt gatgccgtga agcaattcac gaatagcaac
     6361 cttggtttga cgatcacgga tgttggcttc gtctaagtat tcctcgataa attgatcgcg
     6421 gatttctgga gaggtcaatg attcagcagc gagttgttct aggtagagaa cctcaattcc
     6481 ttcatcgcga agagcttggg caaatgcatc atgttctttt tgagcatctt ccaagaaagg
     6541 aatatcatca aaaagaagcc tttcaagata gtccggcaac aagttttcta actccttgcc
     6601 tggacggtgc aacataactt ttttcagttt cccaatttct gagaagacct gaattggatg
     6661 agaagacatg tattttcctc cttaaaaatt ttgacttggc accattttgg gtaccgctta
     6721 catgtatgtt ataacgcaat tcctaggtaa tgtcaatggc tataatttct cggaaaataa
     6781 tataaattat gatgtttagc acaattttat gttattatac ataacatagg atagaataca
     6841 tagatacaaa tgaataaact tctattaaag aggatataaa atttttttaa aaaatttttc
     6901 aaaaaatata caaatgacta aaaagtgtcc aattatcatc tggttatcac ttggatctgt
     6961 ataaagagaa atgtttgtgt gaaaggataa aaagatgcaa cattcttttg aagatagatt
     7021 ttggagaagc atttcttgtt caattgtaca aattatagaa tcttttctga gtatttagga
     7081 agagataatt atcttattga ccctcttttt attttttgtt atagtcgacg aggtgatagt
     7141 ttagaataat cacttattca caatctgtgg aaaagtctgg agagtgaatg gtcttcacac
     7201 aatgacctga aagaagcctg agaataatta tggagagtag cattctgaga ggtgttagca
     7261 gaaccatatg acagagctgt ttgaagaggg aatattgagg agaaaaatcc tgagcctacc
     7321 agttggagtt ggaaagagct ggctgttaga tcatggttta ttatccacaa cctgtggata
     7381 accttgtgaa caagagaagt tgcaaaagaa ggagatatat aacgatgaag aaaatcaaac
     7441 cgcatagacc gttaccaagt cagactcagc tagcttatct gggagatgaa ctagcagcct
     7501 ttatccattt tggacctaat actttttata atcaggaatg gggaacaggt caggaggatc
     7561 ctgaacgctt taacccgaca cagttagacg cacgtgagtg ggttcgcgtg ctcaaggaaa
     7621 cgggcttcaa aaagttgatt ttggtggtca agcaccacga tggctttgtc ctttatccga
     7681 cagctcacac agattattcg gttaaggtca gtccttggag gagaggaaag ggcgacttgc
     7741 tccttgaagt atcccaagct gccacagagt ttgatatgga tatgggggtc tacctgtcac
     7801 cgtgggatgc ccatagtccc ctctatcatg tggaccgaga agcggactac aatgcctatt
     7861 atctggctca gctgaaggaa atcttatcaa atcctaacta tgggaatgct ggtaagttcg
     7921 ctgaggtttg gatggatggt gccagaggag agggcgcgca aaaggttaat tatgaatttg
     7981 aaaaatggtt tgaaaccatt cgtgacctgc agggcgattg cttgattttt tcaacagaag
     8041 gcaccagtat ccgctggatt ggcaatgaac gagggtatgc aggtgatcca ctgtggcaaa
     8101 aggtgaatct tgataaacta ggaacagaag cagagctgaa ctatcttcag cacggggatc
     8161 cctcgggcac gattttttca atcggagagg cagatgtttc catccgtcca ggctggttct
     8221 accatgagga tcaggatcct aagtctctcg aggagttggt cgaaatctac tttcactcag
     8281 tagggcgagg aactccactc ttgcttaata ttccgccgaa tcaagctggg ctctttgatg
     8341 caaaggatat tgaacgactt tatgaatttg cgacctatcg caatgagctc tataaagaag
     8401 atttggctct gggagctgag gtatctggtc cagctctttc cgcagacttt gattgtcgcc
     8461 atttgacaga cggccttgag accagctctt gggcaagcga tgcagacttg cccatccagt
     8521 tagaactcga tttaggttct cctaaaactt ttgatgtaat tgagttaaga gaagatttga
     8581 agctagggca acgaatcgct gcttttcatg tgcaagtaga ggtggatggt gtctggcagg
     8641 agtttggcag gggcttcaca gttggtcata agcgcctctt gcgaggtccg ctagtagagg
     8701 cacaaaaggt gcgcgtgatg attaccgagg cacaatctat ccctgtattg accaagattt
     8761 ccctttataa aactcctggg ttatcaaaaa aagaagttgt tcaggaacta gcatttgcag
     8821 aaaaaagcct agctgtggca aagggagaga ctcttcattt taggattgaa cgtagtgaaa
     8881 gtagctcctc tttagaggct aagatttcga ttcaaccggg gacaggtgtc catggtgtcg
     8941 cctatcagga cgagatttat gtccttgcgt ttcaagctgg tgagactgaa aaaaggctga
     9001 cgctaccaac cttgtatttc gcaggagata aaaccttgga tttctatctg aacctaacgg
     9061 tggatggtca gcttgtggat caacttcaag tccaagtttc ataaaagaag aacctttgcg
     9121 cgatgcaaag gttcttttgg ttattagtga tttggtagcc agctgagggt gaaagttagt
     9181 tgttcagctt ttaggaggtc ttggtgttga atagttgata cgagtgtttt gtccagtcgg
     9241 cattctttga caaagttaaa atggctgtgg ttttgctcag tatgaatatc tagccattta
     9301 ttttctttag ctaggtagac tcgtagatgg tcaaagagag ggattccgag atcatagctt
     9361 ggttttcctg gacaggttgg ataaaatccg agagctgacc agatgtacca agcagagaga
     9421 ctaccattgt cttcatctcc aggataggct tcccaacttg ggtgaaaagc tttctgacgg
     9481 agcgtcttga taagaagggc agtgtagtca gggtaatcgc tgtagcggaa gagataagga
     9541 atgtggaaac taggctggtt ggaaatggct atttgtccaa aaggagcagt agccatctcg
     9601 ctcatttcgt gaatttcgta accatagcct gttgtttcaa agaggggagc atcttgacag
     9661 gctttcaaaa gatagttgct aaaggtttct tttccaccca tcagttggat taagccaggg
     9721 atgtcgtgga gaacgcctaa agtagcttga atggcagagc attcagcgta gtctcgcccc
     9781 caactataag gagagaagtc agggtgaaag tttccttgat tgtctcgtgc tcgcatgtaa
     9841 cctgtctcag cgtcaaatag ctggcggtaa ttttgtgaag cagccttgta ggtttcagcg
     9901 atttctatgt tctctagttt tttggcacag ctggcgatac aaaagtcact ataggcatag
     9961 tctagagtat ggctaacact ttcgtggtgg tcggtagaga ggtaacctag ttcttggtat
    10021 tgggctagtc cgtggcggcc attgatgccg agagggtcgg ctttgctggc tgtttcgagc
    10081 atggcttgga agagttctcc ttctaggtcg ggggccatgt ccttacaggc gctatctgcg
    10141 ataatgccat ctagcagtgt acctggcatc ataccccgtt catctggagc cagccatttt
    10201 ggaaggaaac cagtatcgcg gtagctattg aggaaacctt ctaaaaagcg ttgatagtgc
    10261 tccggtatga taagggcaaa gagggggaag gtggtgcgga aggtatccca gaaaccattg
    10321 ttgctaaaga ggacaccagg cttgacagta ccagtagcca gatccatgtg gatggctttc
    10381 cctgactcat caacctcata aaaagtctgt gggaagagga agagtctgta gaggcagtgg
    10441 tcaaagaagg ttcggtcagc ctctcctgtc tctataatgt caaaacgatg gaggagattt
    10501 tcccaatccg cttgggcact tgttttacag ctatcaaaat cttcttgagg tagattgatt
    10561 agagcttgag aaggagagat gaaagaagtg gctagttgca tctcggtttg actacttgct
    10621 aagtcaattc gccagtcccc agcttcttgg ctgatagcaa gaatatccgt gttcatttgc
    10681 agggcagtga acatcgttag cgaatttttg ttagtttcag ttttaccttc ttgtcgcagg
    10741 gcaagagtcc gcttatctac ttgctctacg gtcagttcat ctgctgcgtg aagatagagg
    10801 gagagggctt tgccttgctt ttgcttcaaa cgaatagaag caccatagca agtcggtgtg
    10861 agctgggttt caatttgata gcgcagggaa aagagcttca aatagtgagg ctggaagcaa
    10921 gctttatcta tatcataaga agactggcgg tgaaagaggc tgtctccccc cagttgactg
    10981 gtgacaggtg tcagaaggag ccaagagtag tccccaatcc aaggactggg ctggtgagtt
    11041 aatcgaatcc cctgaaagat aggcagatgc ggatcaaaaa accaagatcc atcctggtca
    11101 ctggtctggg gcacaaaata attcatccca aaaggcacgc ctgtgtatgg cagggtattt
    11161 ccccgagaga aggcatgttt gctagcagta ccaaagcggg tatcgatggt ttcaagtagt
    11221 ggtttcatag tctttccttt agctgttttt ctacattata tcagaaaaag agggccttta
    11281 gaaaaggagt ttcaaaaata actattttgt agaaaaatga ctatcatttg tgtatgtatt
    11341 ttctgtctca aaagctatat actgaaaatg aaacttgttt gaaagaggaa attgcacgat
    11401 gatttattcg aaagaaattg ttagagaatg gctagatgaa gtagcagagc gggctaagga
    11461 ccatccagag tgggtggatg ttttcgagcg ttgctacacc gataccttgg acaatacggt
    11521 tgaaatctta gaagatggtt caacttttgt cttgactggg gatattcctg ccatgtggct
    11581 tcgagattcg acagcccaac tcagacccta ccttcatgta gctaaaagag atgccctcct
    11641 gcgtcagacc attgcaggtt tggtcaaacg tcagatgacc ttggtactca aggatcccta
    11701 tgctaactcc ttcaacattg aggagaactg gaaagggcac cacgagactg accacacaga
    11761 ccttaacggc tggatctggg agcgcaagta tgaggtggat tcgctttgct atcctttgca
    11821 gttggcttat ctcctctgga aagagactgg cgagactagt cagtttgatg aaacttttgt
    11881 cgcagcgact aaggaaattc tccatctatg gacagttgaa caagaccaca agaactctcc
    11941 ttatcgtttt gtccgagata cggaccgtaa ggaagacacc ttggtaaatg atggctttgg
    12001 acctgacttt gcagtgacag gtatgacttg gtcagccttt cgtccgagtg atgactgttg
    12061 ccagtatagt tacttgattc cgtcaaatat gtttgctgta gtagtcttgg gttatgtgca
    12121 agaaatcttc gcagcattaa acctagctga tagccagagt gttattgctg atgccaagcg
    12181 tcttcaggat gaaatccaag aaggaatcga aaactacgct tacaccacca acagcaaggg
    12241 cgaaaagatt tacgcttttg aagtagatgg cctaggaaat gccagcatca tggatgatcc
    12301 aaatgtacca agtctactag ctgcgcccta tctgggctac tgttcgatcg atgatgaagt
    12361 gtatcaagcc actcgccgta ccattctgag ctctgaaaat ccatacttct accaaggaga
    12421 atacgctagc ggtctcggaa gttctcatac cttctatcgc tatatctggc caatcgccct
    12481 ttctatccaa ggattgacaa caagagataa ggcagagaaa aaattcttgc tggatcagct
    12541 ggttgcctgc gatggtggta caggtgtcat gcacgaaagc ttccacgtag atgatccgac
    12601 cctctactct cgtgaatggt tctcctgggc taacatgatg ttctgtgagt tggtcttgga
    12661 ttacttggat atccgctaag gggctcgctt tagctcaacc gattcttatc agaatcacaa
    12721 gtttacattt aaaacgttaa aatttaaatt tagaatgagg ttttacttca tggaaaatgt
    12781 tgttgtacat attatctcac atagtcactg ggatcgtgag tggtacttgc cttttgaaag
    12841 ccatcgtatg cagttggtgg aattgtttga caatctcttt gatctctttg aaaatgaccc
    12901 tgagttcaag agtttccact tggatggaca aactattgtc cttgatgact acttacaaat
    12961 tcgccctgaa aatcgcgaca aggtccaacg ctacattgac gagggcaaac ttaaaattgg
    13021 tcccttttac atcttgcagg atgactactt gatctccagt gaagccaatg tccgcaatac
    13081 cttgattggt caacaagaag ctgccaaatg gggtaaatca acccagattg gctactttcc
    13141 agataccttt ggaaatatgg gacaagctcc tcaaatcctt caaaaatcag gtattcacgt
    13201 ggcagccttt ggtcgtggtg tgaagccgat tggatttgac aaccaagtcc ttgaagatga
    13261 gcggtttaca tcccagtttt cagaaatgta ctggcagggt gtggatggta gtcgtgtttt
    13321 aggtattctc tttgccaact ggtacagtaa tgggaatgaa atcccagttg acaaagatga
    13381 ggccttgacc ttctggaaac aaaaattgtc agatgtgcgt gcctacgctt cgaccaacca
    13441 atggttgatg atgaacggct gtgaccacca gcctgtacag aaaaatctga gcgaagccat
    13501 tcgtgtggca aatgaactct tcccggatgt aatctttgtt catagttctt ttgatgaata
    13561 tgttcaagct gtagaaggtg cgcttcctga acacttatca actgttacag gcgagttgac
    13621 cagtcaggaa acagatggct ggtacacact tgccaacact tcttcatccc gcatttacct
    13681 aaaacaagcc ttccaagaaa atagcaacct cctagagcaa gtggtagaac ccttgactat
    13741 tatcactggt ggacacaacc acaaggacca gttgacctat gcttggaaaa cacttttgca
    13801 gaatgcgcca catgatagta tctgtggctg tagcgtggac gaagttcacc gcgagatgga
    13861 aacgcgtttt gccaaggtca accaagtagg aaactttgtt aaaagtaatt tgctcaacga
    13921 gtggaagggt aaaattgcta cggataaggc tcaaagtgac tatctcttta ctgtcattaa
    13981 cacaggcttg catgataagg tcgatactgt cagcacagtg attgatgtgg cgacttgtga
    14041 tttcaaggaa ttgcacccaa cagaaggcta caaaaagatg gctgctctta tcttgccaag
    14101 ttaccgtgtg gaggacttgg atggtcgtcc tgtagaggtt acaatcgaag acctcggagc
    14161 taattttgaa tacgatttac caaaagataa gttccgccaa gctcgtattg ctcgacaagt
    14221 gcgcgtgacc attccagttc acctagcacc gctttcttgg acaaccttcc aattgctgga
    14281 aggagaacaa gaacaccgtg agggtattta ccaaaacgga gtgattgata caccattcgt
    14341 aacggtgagt gtggatgaca acatcacagt ctatgacaag acaactcacg aagcctatga
    14401 agactttatc cgcttcgaag accggggtga catcggaaac gagtatatct atttccaacc
    14461 aaaaggaaca gagccaatct ttgcagagct taagggccac gaggtcttgg aaaacacaga
    14521 tcgctatgct aaaatcttgc tcaaacatga attgaccgtg cctgtcagtg cggatgaaaa
    14581 gctagaagaa gagcaacaag gtatcatcga gtttatgaag cgtgaggctg gacggtcaga
    14641 agaattgaca aacattcctc tggaaactga gttgattgtc tttgttgaca atccacaaat
    14701 ccgcttcaag actcgcttta ctaacactgc caaggatcac cgtatccgtc tcttggtcaa
    14761 gactcataac acgcgtccaa gcaatgattc tgaaagtatc tatgaggtgg tgacacgacc
    14821 aaacaaacca gctgcttcat gggaaaatcc tgaaaatcct caacaccaac aagcttttgt
    14881 cagtctgtat gacgatgaaa aaggggtgac tgtatccaac aagggattga atgaatacga
    14941 aatccttggg gataacacca ttgccgtgac cattttgcgt gcatcaggtg agctaggtga
    15001 ctggggctac ttcccaacgc cagaagcaca atgcttgcgt gagtttgaag tcgaatttgc
    15061 gattgaatgc caccaagccc aagaacgctt ctcagcctat cgtcgtgcca aagccttgca
    15121 gacaccgttt accagccttc agcttgctag acaggaagga agcgtggttg cgactggtag
    15181 cctcttgagc cattctgttc tcagcatacc gcaagtttgt ccaacagcct ttaaagtggc
    15241 ggaaaatgaa gaaggctatg tcctccgtta ctataatatg agtcaagaaa atgtgcgcat
    15301 atcagaacat caacaaacca ttcttgactt acttgagcga ccatatccag ttcattcagg
    15361 actattggct ccacaagaga ttcgtacaga attcatcaaa aaagaagaaa tttaatttca
    15421 aaaagtaaac atcaaaagaa aggaggggcg aaaaagtaag aactaactgc tgattcgccc
    15481 ctttttatgg taaaaacaat gaccattgca acgattgata tcggagggac tgggattaag
    15541 tttgccagtc tgactcctga tgggaaaata ctggataaga caagtatttc aacgcctgaa
    15601 aacttggagg atttactagc gtggctagat caacgcttgt cagaacagga ttacagtggg
    15661 attgctatga gtgttccagg tgcagtcaat caagagacag gtgtgattga tggcttcagt
    15721 gcggtgccct acatccatgg cttttcttgg tatgaggcgc ttatctctta tcagctacct
    15781 gtccatttag aaaatgatgc caactgcgtt ggactcagtg aactactagc tcatccagag
    15841 cttgaaaatg cagcctgtgt cgtgattggg acagggattg gcggagccat gattatcaat
    15901 ggtagacttc atcgaggtcg ccacggtctg ggtggagaat ttggctacat gacaaccctt
    15961 gcccctgctg aaaaacttaa taactggtcg caactagcat caactgggaa tatggtacga
    16021 tacgtgattg aaaaatctgg tcatactgat tgggacggtc gcaagattta ccaagaggcc
    16081 gcagctggta atgctctttg tcaagaagcc attgagcgca tgaaccgcaa tttgacgcaa
    16141 ggcttgctca atatccagta tctcatcgat ccagatgtca tcagtctggg tggctctatc
    16201 agtcaaaatc cagattttat ccaaggtgtt aagaaggctg ttgaagactt tgtcgatgcc
    16261 tacgaagaat acacggtcgc accagttatc caggcctgca cctatcacgc agatgccaat
    16321 ctctacggtg ctcttgtcaa ctggctacag gaggaaaagc agtggtaaga tttataggac
    16381 ttagtctcaa acaaacgcaa gctattgagg ttttaaaagg tcacatttct ctaccagatg
    16441 tggaagtggc tgtcactcag tctgaccaag catctatctc tatcgagggt gaggaaggtc
    16501 actatcaatt gacctatcgc aaacctcacc aactttatcg tgccttgtcc ttgttggtaa
    16561 cagttctagc agaagctgat aaagtagaga ttgaggaaca agcagcttac gaagatttgg
    16621 cttacatggt tgactgttct cgaaatgcgg tgctgaatgt ggcttctgcc aagcagatga
    16681 ttgaggtctt ggctctcatg ggctactcaa cctttgagct ttacatggaa gacacttacc
    16741 agattgaagg gcagccttac tttggctatt tccgtggagc ttattcagca gaggagttgc
    16801 aggaaatcga agcctatgct caacagtttg acatgacctt tgtaccatgc atccagacct
    16861 tggcccacct gtcagccttt gtcaaatggg gtgtcaagga agtgcaggag ctccgtgatg
    16921 tagaggacat tcttctcatt ggcgaagaaa aggtttatga cctgattgat ggcatgtttg
    16981 ccacgttgtc taaactgaag actcgcaagg tcaatatcgg gatggacgaa gcccacttgg
    17041 ttggtttggg acgctacctg attctgaacg gtgttgtgga tcgtagtctc ctcatgtgcc
    17101 aacacttgga gcgcgtgctg gatattgctg acaaatatgg tttccactgc cagatgtgga
    17161 gtgatatgtt cttcaaactc atgtcagcgg atggccagta cgaccgtgat gtggaaattc
    17221 cagaggaaac tcgtgtctac ctagaccgtc tcaaagaccg tgtgactctg gtttactggg
    17281 attattatca ggatagcgag gaaaaataca accgtaattt ccgcaatcat cacaagatta
    17341 gccatgacct tgcatttgca gggggagctt ggaagtggat tggctttaca cctcacaatc
    17401 attttagccg tctagtggct atcgaggcta ataaagcctg ccgtgccaat cagattaaag
    17461 aagtcatcgt aactggttgg ggagacaatg gtggtgaaac tgcccagttc tctatcctac
    17521 caagcttgca aatctgggca gaactcagct atcgcaatga cctagatagt ttgtctgcgc
    17581 acttcaagac caatactggt ctaacggttg aggattttat gcagattgac cttgccaacc
    17641 tcttaccaga cctaccaggc aatctcagcg gtatcaatcc caaccgctat gttttttatc
    17701 aggatattct ttgtccgatt cttgatcaac acatgacacc tgaacaggac aaaccgcact
    17761 tcgctcaggc tgctgagacg cttgctaaca ttaaagaaaa agctggaaac tatgcttatc
    17821 tctttgaaac tcaggcccag ttgaatgcta ttttaagtag caaagtagat gtgggacgac
    17881 gcattcgtca ggcctaccaa gcggatgata aagaaagttt acaacaaatc gccagacaag
    17941 aattaccaga acttagaagc caaattgaag acttccatgc cctctttagc caccaatggc
    18001 tgaaagaaaa caaggtcttt ggtttggata cagttgacat ccgtatgggc ggactcttgc
    18061 aacgcatcaa acgagcagaa agccgtatcg aggtttatct ggctggtcag cttgaccgca
    18121 tcgacgagct ggaagttgaa atcctaccat ttactgactt ctacgcagac aaggatttcg
    18181 cagcaactac agccaaccag tggcatacca ttgcgacagc gtcgacgatt tatacgactt
    18241 aatactcttc gaaaatctct tcaaaccacg tcagcttcca tctgcaacct caaaacagtg
    18301 ttttgagcaa cctgcagcta gcttcctagt ttgctctttg attttcattg agtataaaaa
    18361 caagaacacc ttgcttggcg cagggtgttt cgcgtgaaac agaagaagta tctggtttca
    18421 aatgctacag ttaaaattag taaaacaaga aatagaagct gaaaagccag catctgtaga
    18481 agcttggatc atttccgtca aattaaaaaa ggttgctacc gacatatata gattccaaaa
    18541 acaaaaacgt tagcggaact agcagatgtg attttatgga gtttcgattt tgtaaatgat
    18601 catgctcatg catttttcat ggataatgtt gagtggagtc atgcagattc ttactttctt
    18661 agctttgtta gtgacgatgt tgaagaacgt tacatagaaa atgtctatct ggatagccta
    18721 agtgtcaaac aaaaatttaa gtttattttc gacttcggtg atgaatggcg ttttgaatgc
    18781 taagtgctga gagaaatcga gacagaggac gaagaagctt atctcgtacg ttcggttgga
    18841 acgttgccag aacaatatcc agattatgat ggttttgact atgaagaatg gtaaaattga
    18901 aatcagtctg tgtaggctta gtatttcaat agacttcctg caaaactaga atcctagttc
    18961 atgattgata ataccagcaa tcaaattcat tcgtaatccg aagcgtttac gatgatttcg
    19021 atagattgtt gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct
    19081 tctctcctta gatagcgcat ggttataggc tttatcttca gctgttagcg gcttgagttt
    19141 gctggattta cgtggagttt gtgcttgagg atatatcttc atgagtcctt aataaccact
    19201 gtcagccaag attttaccag cttgtccgat atttctgcga ctcattttga acaacttcat
    19261 atcatgacaa tagttcacag cgatatccaa agaaacaatt ctcccttgac ttgtgacaat
    19321 cgcctgagcc ttcatagcgt ggcatttctt tttacttccg tcacatcaat cattaccgtg
    19381 tcctcagaac tgagaggagt tcttgaaatc gtaacaccac ctttgaacaa gagttacttc
    19441 aacccattag ctccgacgga ttaagttgct ttcgtgaata ccaaaatcag ccgcaatttg
    19501 ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt cttctaggct
    19561 taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt ttaatacagc
    19621 taacatctct tcaaaagtcg tgcgttgaac accaacaaga cgcttaaatc gtgcatcggt
    19681 tagttgttta cttgcttcat aattttgttt cgcagggagt ctattgactc tttggtaggt
    19741 gtcaatgttt ttttcatcta tcccgagaat tattttcccg ccatttgtat ttgcaaatgc
    19801 tgagtaggtt tcccagaaag actctggaag attgttttta gcttttttgt attctaaatc
    19861 aaccccttca aattttaagt ccatattttt cctttacatc tgttttttgt ggttctggta
    19921 tttgttcaag ttgagtgata atatagcgaa ttgaatttcg agagttttta ctcagttaat
    19981 ttatttttta acccacttta atttcttttt taacacgggt taaaaaagaa attaaagtgg
    20041 gttaattttc cttgacttaa aatttaaaaa tgatatactg tgtttatgga gagatgacaa
    20101 tttataaaat gtactactct attctactag ataatgattg aataaaactt tttataacaa
    20161 cggctagcaa agttataatt ttatatctat tagaaaataa atatgtaagg aaatttaaat
    20221 gaaaaaaact acaatattat cattaactac agctgcggtt attttagcag catatgtccc
    20281 taatgaacca atcctagcag atactcctag ttcggaagta atcaaagaga ctaaagttgg
    20341 aagtattatt caacaaaata atatcaaata taaggttcta actgtagaag gtaacatagg
    20401 aactgttcaa gtgggtaatg gagttactcc tgtagagttt gaagctggtc aagatggaaa
    20461 accattcacg attcctacaa aaatcacagt aggtgataaa gtatttaccg ttactgaagt
    20521 agctagtcaa gcttttagtt attatccaga tgaaacaggt agaattgtct actatcctag
    20581 ctctattact atcccatcaa gcataaaaaa aatacaaaaa aaaggcttcc atggaagtaa
    20641 agctaaaact attatttttg acaaaggcag tcagctggag aaaattgaag atagagcttt
    20701 tgatttttct gaattagaag agattgaatt gcctgcatct ctagaatata ttggaacaag
    20761 tgcattttct tttagtcaaa aattgaaaaa gctaaccttt tcctcaagtt caaaattaga
    20821 attaatatca catgaggctt ttgctaattt atcaaattta gagaaactaa cattaccaaa
    20881 atcggttaaa acattaggaa gtaatctatt tagactcact actagcttaa aacatgttga
    20941 tgttgaagaa ggaaatgaat cgtttgcctc agttgatggt gttttgtttt caaaagataa
    21001 aactcaatta atttattatc caagtcaaaa aaatgacgaa agttataaaa cgcctaagga
    21061 gacaaaagaa cttgcatcat attcgtttaa taaaaattct tacttgaaaa aactcgaatt
    21121 gaatgaaggt ttagaaaaaa tcggtacttt tgcatttgcg gatgcgatta aacttgaaga
    21181 aattagctta ccaaatagtt tagaaactat tgaacgttta gccttttacg gtaatttaga
    21241 attaaaagaa cttatattac cagataatgt taaaaatttt ggtaaacacg ttatgaacgg
    21301 tttaccaaaa ttaaaaagtt taacaattgg taataatatc aactcattgc cgtccttctt
    21361 cctaagtggc gtcttagatt cattaaagga aattcatatt aagaataaaa gtacagagtt
    21421 ttctgtgaaa aaagatacat ttgcaattcc tgaaactgtt aagttctatg taacatcaga
    21481 acatataaaa gatgttctta aatcaaattt atctactagt aatgatatca ttgttgaaaa
    21541 agtagataat ataaaacaag aaactgatgt agctaaacct aaaaagaatt ctaatcaggg
    21601 agtagttggt tgggttaaag acaaaggttt atggtattac ttaaatgaat caggttcaat
    21661 ggctactggt tgggttaaag acaaaggctt atggtattac ttaaacgaat caggttcaat
    21721 ggctactggt tgggttaaag acaaaggctt atggtattac ttaaatgaat caggttcaat
    21781 ggctactggt tggtttacag tttctggtaa atggtactat acctataatt caggagattt
    21841 attagtaaac acgactacac ccgatggcta tcgagtcaat gctaacggtg agtgggtagg
    21901 ataggtatcc attagctaaa tctaatcatt ctgaactaaa aaatcttctt acatatgtag
    21961 gaagattttt tggattctca aaactagttt aaaagactac gctatttaaa ccaattttaa
    22021 gaatggatat ataaggatat tcagaaatct agttggtcaa cttttgtatt ttgaatatac
    22081 cttagatggt gacgatgtct tggtatatct ggtactcact tacatattct aacttatttt
    22141 aactaagatg caactgtagt tggtgaattt gctacaaata gtgtagaggc gttatttgaa
    22201 aaatatacaa aaaaggaacc ccaacttaca tttgagtttc tcttactttt aatcgtccga
    22261 atccgtattc ttatttcaaa aaatgtagtc attcgaatga tttctcttgc aatatagtga
    22321 aattaacaaa aagaaaaaac gctgatcaag cgtttttctt ctgtattgat tcgtattgaa
    22381 tgcttacttc acttctgtaa acacaacgtg tttgcgaagt tttggtgagt atttcttcaa
    22441 ttgaaggcgg tctggagtgt tacgtttgtt tttagaagta aggtacaagc gttcaccaga
    22501 ttctttgtgt tcaagtgtaa tatttacgcg catggtatct cccttctatt attcagctga
    22561 tgcagcttta gcgattttac gtcctttgta gtatccttta agtgatacac ggtgagaacg
    22621 tgagtaatct ccagtagttt cgtcaaagtt tacagatgga gctgttactt tgtagtgtgt
    22681 acgacgtttg tttttcttcg cttttgaagt gcgacgtgca ggtactgcca ttttgatttc
    22741 tcctttaggt atttatattc gattcaatct actgattttc atcaaccata ctaggataac
    22801 acattttttt tgtaaagtaa agttacttga caaaaaaaga tgaaaaaatt ctcctatccg
    22861 acacggctga aagttctata atgaagttag ccaccttacc ttagtcaaga attagatgtt
    22921 tcactatgtt tgagtaagtt gatgatttca tttgataaca ggtttgaaac tgttaggcta
    22981 ggtg
//
LOCUS       DAVLUM010000032        22195 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLUM010000032 DAVLUM010000000
VERSION     DAVLUM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22195
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.032"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            1945..3281
                     /locus_tag="VYN42_001110"
                     /pseudo
     CDS             1945..3281
                     /locus_tag="VYN42_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            3262..3465
                     /locus_tag="VYN42_001111"
     CDS             3262..3465
                     /locus_tag="VYN42_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462193.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            3468..3818
                     /locus_tag="VYN42_001112"
     CDS             3468..3818
                     /locus_tag="VYN42_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462194.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            3827..4243
                     /locus_tag="VYN42_001113"
     CDS             3827..4243
                     /locus_tag="VYN42_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV1462195.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLFRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4247..4579
                     /locus_tag="VYN42_001114"
     CDS             4247..4579
                     /locus_tag="VYN42_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1462196.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKNLDTFVESAVKQ
                     MNDVWKGR"
     gene            4583..5539
                     /locus_tag="VYN42_001115"
     CDS             4583..5539
                     /locus_tag="VYN42_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1462197.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLTKWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5810..5989)
                     /locus_tag="VYN42_001116"
     CDS             complement(5810..5989)
                     /locus_tag="VYN42_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462198.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(6131..6280)
                     /locus_tag="VYN42_001117"
     CDS             complement(6131..6280)
                     /locus_tag="VYN42_001117"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462199.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            6562..7029
                     /locus_tag="VYN42_001118"
     CDS             6562..7029
                     /locus_tag="VYN42_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1462200.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            7062..7159
                     /gene="ffs"
                     /locus_tag="VYN42_001119"
     ncRNA           7062..7159
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYN42_001119"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            7216..7659
                     /locus_tag="VYN42_001120"
     CDS             7216..7659
                     /locus_tag="VYN42_001120"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1462201.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            7661..8176
                     /locus_tag="VYN42_001121"
     CDS             7661..8176
                     /locus_tag="VYN42_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1462202.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGEMLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            8190..9551
                     /gene="radA"
                     /locus_tag="VYN42_001122"
     CDS             8190..9551
                     /gene="radA"
                     /locus_tag="VYN42_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1462203.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            9624..10121
                     /locus_tag="VYN42_001123"
     CDS             9624..10121
                     /locus_tag="VYN42_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1462204.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     AVVEL"
     gene            10146..10961
                     /locus_tag="VYN42_001124"
     CDS             10146..10961
                     /locus_tag="VYN42_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1462205.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLLGWLSSFANTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKFLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            11106..12074
                     /locus_tag="VYN42_001125"
     CDS             11106..12074
                     /locus_tag="VYN42_001125"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1462206.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(12208..12489)
                     /locus_tag="VYN42_001126"
                     /pseudo
     CDS             complement(12208..12489)
                     /locus_tag="VYN42_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12618..12851)
                     /locus_tag="VYN42_001127"
     CDS             complement(12618..12851)
                     /locus_tag="VYN42_001127"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462207.1"
                     /translation="MFSQLHMREEQVLLAQDYPLETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(12844..12960)
                     /locus_tag="VYN42_001128"
                     /pseudo
     CDS             complement(12844..12960)
                     /locus_tag="VYN42_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            complement(13175..13525)
                     /locus_tag="VYN42_001129"
     CDS             complement(13175..13525)
                     /locus_tag="VYN42_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1462208.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            13781..16414
                     /gene="polA"
                     /locus_tag="VYN42_001130"
     CDS             13781..16414
                     /gene="polA"
                     /locus_tag="VYN42_001130"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1462209.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            16499..16936
                     /locus_tag="VYN42_001131"
     CDS             16499..16936
                     /locus_tag="VYN42_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1462210.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLLDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(17119..18129)
                     /locus_tag="VYN42_001132"
     CDS             complement(17119..18129)
                     /locus_tag="VYN42_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1462211.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            18278..19447
                     /locus_tag="VYN42_001133"
     CDS             18278..19447
                     /locus_tag="VYN42_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1462212.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            19444..20214
                     /gene="recO"
                     /locus_tag="VYN42_001134"
     CDS             19444..20214
                     /gene="recO"
                     /locus_tag="VYN42_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1462213.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMETGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            20211..21203
                     /gene="plsX"
                     /locus_tag="VYN42_001135"
     CDS             20211..21203
                     /gene="plsX"
                     /locus_tag="VYN42_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1462214.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            21209..21442
                     /locus_tag="VYN42_001136"
     CDS             21209..21442
                     /locus_tag="VYN42_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1462215.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            21488..21778
                     /locus_tag="VYN42_001137"
                     /pseudo
     CDS             21488..21778
                     /locus_tag="VYN42_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            21981..>22195
                     /gene="blpU"
                     /locus_tag="VYN42_001138"
     CDS             21981..>22195
                     /gene="blpU"
                     /locus_tag="VYN42_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1462216.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAA"
BASE COUNT         6506 a         4010 c         5345 g         6334 t
ORIGIN      
        1 agccgtctga ctgaaggcct tagaaccaaa gcggatatca gctcactcaa tgtgactgct
       61 gaaaatatcc ggcaatctgt gaagagcctt gagacagaca cgcagaacaa gctaaatcag
      121 aagttgagtc aggctgaatt tgaggtgcga gctggctcta tccgtcagga aatcctgaac
      181 gcaaccaagg ataaagcaga taagacttta gttgtatctg aagctgggaa attgcgtgaa
      241 gaattttcaa aaatgaaggt gggaggacgg aatctatgga taaaatccaa gacggttgga
      301 gctgtaattg aaaaattacc tgaaaaccac gtcacaggtc aaaaagaatg ctataggcta
      361 gagaacaact ctactttaac gttcaacatt gaaccagatt tcagctcaag gttgtatcaa
      421 aaagttactt ttagcgcttg ggtcaagtac gaaaatgtag tccaaggtcg aaatttttgg
      481 aatgtattta attgcttcaa acattatctt tttagaaaaa atagtgagac cggagtacag
      541 agtggtccag attatgctac gcttggtatg tataaaggtt cggcagattg gaaatatatt
      601 acattcactt atgactactc tgaaaaaaca aattttgatc aattgaagac atcattgcga
      661 ttcaatcttg aaggtgctac aagcggtaca gcttgggtaa caggaatcaa ggttgaaatc
      721 ggtagtgtgg cgacggactg gagtcctgcg cctgaggacg ctgatggtct catcactgaa
      781 gctaaggcta cctttgagcg gacagctcag ggcttgcgaa ccgatttatc agctattcag
      841 gaatatgtaa ataaagacgg tcagcgacag gaagccctac agcgctatac tcgtgaggag
      901 agcacgagac aagcgatagc agtccgtgag ctggtcaatc gtgatttcgt tggtaaggct
      961 acttatcaag aagatgttaa gggtatcaat caaaggattg aagctgttaa aactagtgcg
     1021 aataaagaca tcgctagtca aatcgctagc tatcgtcaat ctgtagatgg taagttcacg
     1081 gatatttcaa gtcagataac tacttataag caagatgtgg gcggtcaaat cagtggcctt
     1141 tcaaatagac ttacaagcag tgagcaagga accactactc agatttcaaa tctttcaaat
     1201 cggataaaca gtaataaaca aggcgcagat aatcagattt caaatttaaa gactcaggtc
     1261 gctacaaaca aggataatgc tgaacgacaa atgggtagaa tatctgatca ggtttctgca
     1321 aacaaagcga atgctgatag tcaatttgcg aatgtgacca atcaactagt gcgaaaagta
     1381 gagactactg acttccagcg tgttaaggaa accagtaaac tttacgagcg gattttgggc
     1441 aatactgaaa atggaattgc ggataaggtt gctcgcatgg ctctgaccaa tcaactgttt
     1501 caggttgagg ttgggaaggt tgccaaaggt ggtcgaaatt atatcagaaa tggtcaattt
     1561 aagaacggtt cgaaaaactg gcttgaatat caatctgtta attttggttt gaatttcaac
     1621 tatcaacact ctcaaaatcc taataatcga aatcgtccag gactacactt ctatcacgat
     1681 tctcaagatg ttgctaattt ttttggaatt cagcaatctt ttgcatttga tggtgttcga
     1741 ggtgagaaag tgagtgtatc tcttcttgtt tcgaaagatg gtggcgatag caacagtggc
     1801 ttgaaagtcg ctttgcacta catcaaaaac aaaaacatta ttgggcaaga gtggcaaaat
     1861 atcccaagtc cacaaataac atcgaagtat aagcgtttca catttacgtt tactttatca
     1921 gacgatgtag agaatctgaa tttgatgttg tttggtgaaa aagggaagac catcaacctc
     1981 tatgttacag atgttcaact cgaaagaggt tctgtcgcga cggattacaa agaagctcct
     2041 gaagacacgg acgaagcgat tcgctctgtt caaagccaac taactggctc atgggcagtt
     2101 caaaacatca actcggctgg agatatcatc tctggaatca atcttggcgc caatggacat
     2161 aaccgctttg ttgggaaatt gacccacatc actggagaga ccctgattga cagagcagtc
     2221 atcaagtctg ccatggttga taagctcaaa acggccaatt ttgaagctgg ttcggtcacg
     2281 actacgatat tagacgctga agcggtaact gctgagaagt tgaaagttga caatgcgctt
     2341 attagaaaat taactgcaaa tgatgctttt attgaccaac tgatatctaa acgtatcttc
     2401 tctactaagg ttgagtccgt catttctagc tcaaccttcc tagaagccta tcaaggccga
     2461 atcggtggat tcacacttgg tcaatttgac cagggtggcg gtcgctggat ttcaggtgtc
     2521 aatcagttct ctgttggtat ggggaatggt gccgggtatg gagtccggac agccttctgg
     2581 gcgaactggg gaaataattg gaactatgcc ggacctaaag catggaacgt caatactgat
     2641 gggaaaatgt actgtaggaa tgaagtcggt ttttatgatc aagtggattt ttcgaattca
     2701 tcgagagcaa acttctatgg gaatactact ttttctcgtt ctcctgtgtt ttcaaatggt
     2761 atcgaacttg gaagtaaaga tgtgcttggt gatggttgga atcccaaagg cggaaggaat
     2821 gcggttgttt ggtggaatca ggtcggtagc ggtagcgtga agtattggat ggaacaaaaa
     2881 tcagacagac gcttaaaaga gaacatcaca gatacagctg tgaaagcctt ggacaaaatc
     2941 aacagattaa gaatggttgc atttgatttc atcgaaaata aaaaacatga ggagattggt
     3001 ctaatagctc aagaggctga aaccatcgtt ccaaaaattg tctcacgaga tcctgagaat
     3061 ccagatggct atctgcatat cgactatacc gctttagttc cttacttaat caaggctatt
     3121 caagaattaa atcaaaaaat agaaaaaatg gagaaaacaa tagcatgaat aacaacatgt
     3181 tgaccaatat cgcacttaaa gcaatttagg agcttgctct tgaaaataga aaacgaacac
     3241 acagattgga gaacttagaa aatgaacaca gaacagctta accaagcctt acaaatgaca
     3301 attagtgaaa tgtcaacaac ttcaacaaat tcgatgatta caagtaatat cttgagtatt
     3361 cagttgaatg agcaaaggga agagaatcaa agacttcaag cacgagtgga tgagctggaa
     3421 gctctgcttg atgaacaaac taaaccagca gacaaaggag aatagacatg gcagaaacaa
     3481 ttcaaaacac agataactta ctagacctta caaaaatcac agaaccattt gatcttgcga
     3541 gcgctttgcg ctacatgaaa gaaaatggag agttcattcg ttgcaagaat gtaagcgatg
     3601 acttctatat gtatcgtgac gttcaaaaac gtcctgtgat cgtaaatggc cgtcgccaat
     3661 tcaaggatgt tgaaaccgtt tgggcgttca atcagtgggg tggtacaatc gcaacaatca
     3721 acgtagccgt tctgttgaat catgaattct atatcatgaa atttgatgca gagggcaatc
     3781 ctgactggac ggttccaacg gtagaaccta aagaatagga ggttgtatgc aaattgaatt
     3841 tttcaatttt ctaagaagtg tcgtacagac tgaagatggt ttggtattgt acgctctagc
     3901 actgattgtc tcaatggaaa tcattgattt tgtgacaggg acgattgcgg caattatcaa
     3961 tcctgacatc gagtacaaga gcaaaatcgg catcaatggg ctatttcgta agatttcagg
     4021 ggttctctta ctgatgatcc tcattccggc gtccgttttg ttgcctgaaa agacaggttt
     4081 tgcattcttg tactcaatct atctcgggta catcgcattt acttttcaat ctctcattga
     4141 aaattaccgc aaattaaaag gaaatgttac tctttttcag ccgattgtaa aagtatttca
     4201 gcgattactt gaaaaagatg atgatacgaa aaaaggagaa taacaaatgc aacaaattac
     4261 tgaaatcatt actaatggag caatcagcat ccttgttatt ttggctggta tcgcagtcaa
     4321 ggcagtcaag gactacctgg ttcaaaaagg tggagaaaag accatcaaaa tcgttgaaat
     4381 cttggccaaa aatgcagtaa atgccgtgga gcaggtagct gctgaaactg gctacaaggg
     4441 agatgaaaaa ctggcacagg ctcgtgctaa agtccgtgct gagcttacaa aatacaatat
     4501 tagcatgact gacaaaaact tagacacctt cgtagagtca gcagtgaagc agatgaatga
     4561 cgtatggaaa ggacgatagg gaatggatat cgatagaaac agactacgta caggcttgcc
     4621 acaggttggg gtgcagcctt atcgacaagt acatgctcac tcaacaggta accgcaactc
     4681 aaccgtacag aatgaagcgg attatcactg gcggaaagac ccagaattag gttttttctc
     4741 gcacgttgtt gggaacggcc gtgtcatgca agtaggtcct gtgaacaacg gaagttggga
     4801 tgttgggggc ggttggaatg ctgagagtta cgcagcggtt gaactgattg aaagccattc
     4861 aactaaggaa gagtttatgg ctgactaccg cctctatatc gaattgctac gcaatctagc
     4921 ggacgaagca ggcttgccga agactcttga tacagacgac ttggcaggta tcaagacgca
     4981 tgaatactgt accaataacc aaccaaacaa ccactcagat catgtggatc cataccctta
     5041 cttgacaaaa tggggcatta gccgtgaaca gtttaagcaa gacatcgaaa acggcttgag
     5101 cgctgcaaca ggctggcaga aaaatggcac tggctactgg tacgtacact cagacggctc
     5161 ttatccaaaa gataagtttg agaaaatcaa cggtacctgg tattatttcg atggctcagg
     5221 ctatatgctt tcagaccgct ggaagaagca cacagacggt aattggtact actttgacca
     5281 atcaggcgaa atggctacag gctggaagaa aatcgctgag aagtggtact attttgatgt
     5341 agaaggtgcc atgaagacag gctgggtcaa gtacaaggac acttggtact acttagacgc
     5401 taaagaaggc gccatggtat caaatgcctt tatccagtca gcggacggaa caggctggta
     5461 ctacctcaaa ccagacggaa cactggcaga caagccagag ttcacagtag agccagatgg
     5521 cttgattaca gttaaataaa atagaaagga aactttctaa attgttcttt caccgcaggc
     5581 tcaggcttgc ggtttttttg tttgtctgaa tcaagaaaac gtctaaccaa ccgacaccaa
     5641 tgtcggtagc aaaataaatg gtttgcctaa aaaattagag ttaagttcta tttttcaaaa
     5701 acacgcattt tgaacgatta gaaacagaaa tctaaatcct attgttcaaa aaaacgttta
     5761 catgaaaaat agggaggtgt tttgttaaaa ataaaaacag tgatcgaaat cactgcttat
     5821 cagttgtagc aaattcataa agtttttctg ctgtgagaag tgccattttg tccatgcttg
     5881 tttttccttt tctgaggtca gaaacagtag tccatggaac tccagcacct tgggaaatag
     5941 cagatgtaga catcgaactg tctaacaatt cttgaataac ttctctcatc ttatttgtcc
     6001 tttttatttt ttagataaat atatacattg attgcaatta taaaaatagc tattgcacta
     6061 accattgcat ttcctctttc catttgataa aatagaggtg taaggggctt tcgccccaac
     6121 ctcttagcgt ttaccttttt ctttgacggg atttcggttt acgctttttg ttttgccttg
     6181 cgaccgttat tgcggtcact agacttgcga tagcagttac cgtttcagga atattgtcta
     6241 ttgccttttc aagtaacctg agccaatctt ctttgttcaa cttcatcacc ccctttcctt
     6301 atcttgatta tattatatca cggtacaccg agaaagtcaa gcgttttgat gaagtttttt
     6361 taattttttc aaaaaaaaaa tagaccttgt ccagaggtcg gggagttgga ggggacaccc
     6421 tccaagagtg ttgatttaat aagattttat tttacctttt tcataataat ctccctatag
     6481 agtcaccgca ttcggtggct ttttttgtgt tgggattcat gatataataa taaaatcgat
     6541 aagtaggaaa agagaaaaga gatgtattat acgcttgaag aaaaagaagt ctttatgagg
     6601 gaggctttga gagaggctga gattgctctt gaacacgatg aaattccaat tggttgtgtg
     6661 attgtcaaag atggggaaat cattggtcgt gggcataatg cgcgtgagga attacagcga
     6721 gcggttatgc atgcggaaat tatggctata gaggatgcga acttgagtga ggagagctgg
     6781 cgcttgctgg attgcacact ttttgtgacc attgaacctt gtgtcatgtg tagtggggcg
     6841 attgggcttg cccgcattcc aaatgtggtc tatggggcta aaaaccagaa atttggcgct
     6901 gctggaagtt tgtacgatat cttgacagat gagcgtctta accatcgtgt agaggttgaa
     6961 acgggaattt tggaagatga atgtgcagct atcatgcagg acttttttag aaatagacgg
     7021 aaaaaataat tttgctttta aaatgaatag gaatgtgata taataaatag tggagcaaca
     7081 gttctgcgtg aagcgggtca ggggaggaat ccagcagccc taagcgattt gaattgtgtg
     7141 ctcttttttt cgtgcttttt ccgaataaat aagatagaat aatctagaat aaatgataat
     7201 agaaaagaga aaattatgaa aattcgtggt tttgaattgg tttcgagttt tacagatgaa
     7261 aatttattgc ccaagcgtga gacagcgcat gcggctggtt acgacttaaa ggttgctgtg
     7321 cgtacagttg ttgcgccagg agagattgtc ttggttccga caggggttaa ggcttatatg
     7381 cagccgactg aggttctcta cctctatgat cgttcttcaa atcctcgtaa gaagggcttg
     7441 gttttaatta actcagttgg ggtcattgat ggggattatt atggaaatcc tggaaatgaa
     7501 gggcatattt ttgcgcagat gaagaatatc acagaccaag aggttgttct tgaagttggg
     7561 gaacgtattg tccaggctgt ttttgctact ttcttaattg cagatggaga tgcagctggt
     7621 ggcgttcgaa ctggtggatt tggatcgaca gggcactaga atgaagatta tctttgtacg
     7681 tcatggggag ccagattacc gtgagttaga ggagcgttct tatataggat ttgggataga
     7741 tttggcaccc ttgtctgaga tgggacggca gcaagtccag aaattgagca aaaatccttt
     7801 actctcgtca gctgaaataa tcgtatcttc tgcagtcaca agagctttag aaacggcttc
     7861 gtatgtggtc tgtgctacgg gtcttccttt aagagtagag cctttattac atgaatggca
     7921 ggtctataaa acaggaatag aaaactttga aacagctaga agactgtttt tagaaaacaa
     7981 gggggagatg cttcctaata gtcctattca atatgagaca gctacggaaa tgaagtctcg
     8041 gtttctagaa tgtatgtcta agtatcgaga acatcagact gtggtagttg ttgctcatcg
     8101 aatgctcatg cgccagtttg tgccaaatga gaagattgat ttttgccaag tgattgagtg
     8161 tgagttagag atatagaaag aggtttgtca tcgcaaagaa aaaagcgaca tttgtatgtc
     8221 aaaattgtgg gtataattcc cctaaatatc tgggacgttg ccccaactgt gggtcttggt
     8281 cttcttttgt ggaagaggtt gaggttgccg aggtcaagaa tgcgcgtgtg tccttgacag
     8341 gtgagaaaac caagcccatg aaactagctg aggtgacttc catcaatgtc aatcgaacta
     8401 agacggagat ggaggaattc aaccgtgtgc ttggaggcgg agtggtacca ggaagtctcg
     8461 tcctcatcgg tggggatcct gggattggga aatcaactct tctcctacaa gtctcaaccc
     8521 agttgtccca agtggggaca gttctctatg tcagtgggga ggagtctgcc cagcagatta
     8581 aactacgtgc agagcgctta ggtgatattg atagtgagtt ttatctctat gcagagacca
     8641 atatgcagag tgttcgtgca gaagtggagc gtatccagcc agactttctc attattgatt
     8701 ccatccagac catcatgtct cctgagattt caggggtgca ggggtctgtt tctcaggtac
     8761 gtgaagtgac cgctgaactc atgcagttgg ccaagaccaa taacattgcc atctttatcg
     8821 taggtcatgt gaccaaagaa ggaaccttgg ctgggcctcg tatgttggag catatggtgg
     8881 atacggtgct ttactttgaa ggggagcgtc accacacctt tcgtattttg agagcggtca
     8941 aaaatcgttt tggttccact aatgagattg ggatttttga gatgcagtcg ggcggcttgg
     9001 ttgaggtact caatccgagt caagttttcc tagaagagcg tttggatggg gcgactggtt
     9061 cctccatcgt tgtaaccatg gaagggacgc gtccgatttt ggcggaggtt caggctttgg
     9121 taacaccgac catgtttgga aatgccaagc gtactacgac aggacttgat tttaaccgtg
     9181 ctagcttgat tatggctgtt ttggaaaaac gggcagggct tctcttgcaa aatcaggatg
     9241 cctatctcaa atctgctggt ggtgttaaat tggatgaacc tgccattgac ttggctgttg
     9301 cagttgctat tgcttcgagc tacaaagaca agccaactaa tcctcaggaa tgttttgtcg
     9361 gagaactggg cttgacagga gagattcggc gcgtgaatcg tattgagcaa cgcatcaacg
     9421 aagctgctaa actgggcttt actaagattt atgtacctca gaattccttg acaggaatca
     9481 ctctgcctaa ggaaattcag gtcattggcg tgacaacgat tcaggaagtc ttgaaaaagg
     9541 tctttgcata atccgtgaca aattctctta aaaatgataa gataggagaa atatttgact
     9601 atcaaatttt caaggaggga atcgtgtcgt attttgaaca gtttatgcaa gccaatcagg
     9661 cttatgttgc cctacatggg cagttaaatc tgccacttaa acctaaaacc agagtagcca
     9721 ttgtgacctg tatggactca cgtttgcacg ttgcgcaagc tctaggtttg gcacttgggg
     9781 atgctcatat tttgcggaat gcaggtggtc gagtgactga agacatgatt cgttcgctag
     9841 ttatttccca gcaacaaatg gggacaagag agattgtggt attgcaccat acagactgtg
     9901 gtgctcagac ctttgaaaat gaaccttttc aggagtattt aaaagaggaa ttaggtgtag
     9961 atgtgtcaga ccaggatttc ttgcccttcc aagatataga agagagtgta cgcgaggata
    10021 tgcaactgct tatcgagtct cccctaatac cagacgatgt cattatctct ggtgccattt
    10081 acaatgttga tacaggaagt atggcagtcg tagaattata aatacttcat ttagaaagaa
    10141 agtgtatgaa gaaaagcagt attttattta tttttatttt attgctatgt attggtttac
    10201 agtatgaaac catctactat acggacggtt cgaggtcagg tgcggaatat ggactaatgg
    10261 gagtttctat ctttctagct ctcttttaca tgattccggc tctttatttt ctcttccgta
    10321 ttgggaaaaa atgggaattg ccaaagaagg ttttgattct gtctttattg ggagggatgt
    10381 tccttttagg ctggttgtct agttttgcta atacttatat ccatgattta ctgggggttc
    10441 ttttcccaga tagtccattt ttaaatgcct ttgaaagtgc tattgtggct cctttggtag
    10501 aagaaccctt gaaattattg ccacttgttt ttgttttggc tttgattcct gtgcgaaaat
    10561 taaaattttt gtttttactt ggaattgctt ccggtttggg attccaaatg attgaggata
    10621 ttggttatat tcgtacggat ttgccagagg gctttgactt tactatttcg cgaattttag
    10681 agcgtatcat ctcaggaatt gcctctcact ggactttttc aggtctagct gtagtaggtg
    10741 tttacttgct ttacagagcc tataaaggac agaaggttgg caagaaacag ggccttattt
    10801 ttctaggttt agccttggga actcacttct tgtttaactc tccttttgtg gagttggaaa
    10861 cagagttgcc tttagcgatt ccagtggtta cggctattgc tctctatggt ttttatcatg
    10921 cttattgctt tgttgagaaa cacaatgagt tgatgaccta gaatattttt caaaagaatg
    10981 atgcaagggt acaaatatgg tgcccttctt ttatttttga ttgaaaaata gtgcaaaaag
    11041 cgctacaatg gtagatggaa aatcttgtga aaagcacaag ttatacatat ataccggagg
    11101 aaatcatgtc tttttctgat ttaaagctgt ttgccctttc ttctaataaa gaattggcag
    11161 aacgtgtggc gcaggagatt gggatagagt tggggaaatc aagtgttcgc caattttcag
    11221 atggagagat tcaggtcaac attgaagaat caatccgtgg gaaacacgtc tttatcctac
    11281 aatcaactag ttcgcctgta aatgacaatc tgcttgaaat tttgattatg gtagatgctt
    11341 tgaagcgtgc gagtgcagaa tctgtcaatg ttgtcatgcc ttactatggg tatgcacgtc
    11401 aggatagaaa ggcgagagcg cgtgagccaa tcacttcaaa acttgtcgca aatatgcttg
    11461 aagtagctgg agtggatcgt ttattgacca tcgacttgca tgctgcgcaa attcaaggat
    11521 tctttgatat tcctgtggat catttgatgg gtgctcctct gattgcagat tattttgagc
    11581 gtcgtggtat ggttggttct gactatgtgg ttgtcagccc ggaccatgga ggggtgactc
    11641 gtgctcgtaa gttggcagaa tttttgaaaa catctatcgc tattattgat aaacgtcgta
    11701 gcgttgataa gatgaatact agtgaagtta tgaacatcat cggtaaggtt gaaggcaaga
    11761 cttgtatctt gattgatgat atgattgata ccgctggaac gatttgtcat gcggcagatg
    11821 ctcttgcgga agctggtgct gttgaagtct atgcaagctg tacgcaccca gttctttctg
    11881 gtcctgctac ggacaatatc caaaaatcag ctattaagaa attggttgtt ttggatacca
    11941 tctatcttcc agaagagcgt ttgattgata agattgagca gatttcaatc gctcatctcc
    12001 taggggatgc tatcgtacgt attcatgaaa aacgaccact ttctccactt ttcgatattg
    12061 agaaaaaaat ttaatgacca agcctgagat gattctcagg ttttttcgtc ttttttccga
    12121 ataaatagat agtagcggtg aatctagtaa agctagattt aaaactgtga tataataaaa
    12181 agagaagaaa tatgactgta cgtcatcaga agtttcagcg accatcattt ttgaacagtg
    12241 atagcacttg aatcgacgct ttctaaggag aattctagta ggcataccag tcgtttcaag
    12301 ataaggaatt ttagaaggtt tttgaaagtc atatttcttc aattgacttc cgcactcagg
    12361 gcaagatggg gcgtcgtagt ccagtttggc gatgatttcc ttgtgtgtat ccttattgat
    12421 gatgtctaaa atctggatat tagggtcttt aatgtctagt aattttgtga taaaatgtaa
    12481 ttgttccata tgattctttt taatgagttg ttttgtcgct tttcattata ggtcatatgg
    12541 gacttttttt ctacacaaaa ataggctcca taatatccat aggggattta cccactatgg
    12601 atattatgga gcctatttta caacagtgcc tcaaattcag atactgacat acctaattgc
    12661 tggctggcaa cctcagaagt cagaagacct tggcgtacta tgtctaggaa ggcaaaaagt
    12721 ttcctttctt cccttccttc aactttccca cgctctagtc cttgttcaag gccttcagcc
    12781 ctagcagttt ccaagggata gtcctgtgct aacaagactt gttcttctcg catatgtagt
    12841 tgactaaaca ttttcctgtc ctcctcggac cagctcttgt agtccagcag ttggtctgct
    12901 tggctgatgg ctcgctcagg ttgctgggta aagggcttgt tgccgaaaaa ctccaaccat
    12961 ggcttgcgaa ccttgtcttt gctggtttct ctgtattttt taattccaag aatgccatct
    13021 taaccagatg gttttcctgt ccattgttgg taatcgccaa tacctcacct gttgtgtctt
    13081 cgcgcatact aaagctatga aaagccaggt catctgagaa ataattacta tccacgatag
    13141 caatggcgta aacaggagcg atgtgtttgt agctctagtg agtatcacct tctcgctgac
    13201 gaattttttc aagattttga ttaacctgac tgcacaggta agcccacaag tgattgatga
    13261 aaaaattctg atgatggact tgaatctcaa taattacttg agtaccgtta tccaactccg
    13321 ccaagacgtc tatactggta taaaaatcct gcaccgagta aggcatggag agtaatacgt
    13381 gaatatcgct tccctccaaa atggtcacat tttttgctgg caagtccagc atatcgcgaa
    13441 taaattgaca agtgatttct ggattgctga atattttctt agcaatcaaa tcattagttg
    13501 ggctgatgcc cggatgtctg agaatcctcc tattcctcct tctatagtga gttgaaataa
    13561 gatgtgaata actctatcag gaaagtcaaa ttaatttata gaaatatttt agcagtcaag
    13621 gtgtactatt atagattcaa tatactatgt tatagcacat ttttaaatct aggtttacta
    13681 aattctctgg ctctatctat ttattcggaa aaagtttgaa aaatacttgc tctagctctt
    13741 cccaatggta ttttttgatt ctttccttta taatgggtgt atggataaga aaaaattatt
    13801 attgattgat gggtcttctg tagcttttcg ggcgtttttt gcgctgtatc agcagttgga
    13861 ccgttttaag aatgcggctg gtttgcatac caatgcgatt tatggtttcc agttgatgtt
    13921 gagtcatttg ttggagcggg ttgagccgag tcatattttg gtggcttttg atgcgggaaa
    13981 gacgaccttc cggacagaga tgtatgcgga ctataagggt ggtcgggcca agactcctga
    14041 tgagtttcgt gagcaatttc ctttcattcg tgagttgctg gatcatatgg ggattcgtca
    14101 ctatgagctg gctcagtatg aggcggatga catcattggg acgctggata agctagcaga
    14161 gcaggatggt tttgatatta ccattgtcag tggggacaag gatttgattc agctgacgga
    14221 tgagcatacg gtggttgaaa tttccaagaa aggtgtggct gagtttgagg cctttacgcc
    14281 agattacctc atggaagaaa tgggcctcac accagctcag tttatcgatc tcaaggcgct
    14341 catgggtgat aagtcggata atatccctgg ggtgaccaaa gtcggtgaaa agacgggtat
    14401 taagctcttg ctggagcatg gttcgcttga ggggatttat gaaaatattg atggaatgaa
    14461 gacttctaag atgaaggaaa atctcatcaa tgacaaggaa caggcctttt tgtctaaaac
    14521 actagcgacc attgatacca aggcaccgat tgcgattggt ttagaggact tggtctatag
    14581 tggtccagat gttgaaaatc ttgggaaatt ttacgatgag atgggcttca aacagctcaa
    14641 gcaggcttta aatgtgtcgt cagctgatgt ggctgagggt ttggatttta ctattgttga
    14701 ccaaatcagt caagatatgc tgagtgaaga gtctatcttc cactttgagc tttttggtga
    14761 gaattaccat acggataatt tggttggatt tgcctggtct tgtggggata agctctatgc
    14821 cacagacaag cttgagctgt tgcaagaccc gattttcaag gatttcttag aaaaaacatc
    14881 tctgagagtt tatgacttta agaaggttaa agttcttttg caacgttttg gtgtggattt
    14941 gcaggcgcct gcttttgaca tccgtttggc taaatacctc ctttcgactg tggaggacaa
    15001 tgaaattgcg accatcgcta gtctttatgg tcagacttac ttggttgatg atgaaacttt
    15061 ctacggtaag ggtgttaaaa aggccattcc tgaacgtgag aaattcttgg aacacttagc
    15121 ttgtaaactt gctgttttgg tagaaacaga gcctatttta cttgaaaaac tcagcgaaaa
    15181 tgggcaatta gagcttcttt atgatatgga gcaacctctg gcttttgttc ttgccaagat
    15241 ggaaattgct gggattgtgg tcaagaaaga gaccttgctt gagatgcagg ctgaaaatga
    15301 gcttgtcatt gaaaaactga ctcaagagat ttacgagctg gctggtgagg agtttaatgt
    15361 caactcgcct aagcagttgg gcgtgcttct ctttgagaaa ttgggacttc ctctagaata
    15421 cactaagaaa accaagacag gttattcgac agcagtggat gtgttggagc gtctcgctcc
    15481 tattgctccg attgttaaga aaatcctgga ttaccgtcaa attgctaaga ttcaatctac
    15541 ttatgtaatt ggcttgcagg actggatttt ggctgatgga aagattcata ctcgctatat
    15601 gcaggatttg acccagaccg ggcgtttgtc tagtgtggat ccaaacttgc aaaatattcc
    15661 tgcccgattg gaacaagggc gcttgattcg gaaggctttt gtgccagagt gggaggatag
    15721 tgtgctactc agctctgact attcacagat tgaattgcgc gttttggcgc atatttctaa
    15781 ggatgagcac ttgattaagg ccttccaaga gggggcagat atccatactt cgacagccat
    15841 gcgggtcttt ggcattgagc gtcctgataa tgtgactgca aatgaccgtc gcaatgccaa
    15901 ggcagttaac tttggagtgg tttatgggat ttcagacttt ggcttgtcta ataatttggg
    15961 aattagtcgt aaggaagcca aagcctacat tgatacctac tttgaacgtt ttccaggtat
    16021 taaaaactac atggatgaag tggtgcggga ggcgcgtgat aagggctatg tagagaccct
    16081 ctttaagcgt cgccgtgagt tgccagatat caattcgcgc aacttcaata ttcgtggttt
    16141 tgcggagcga actgctatca actcacctat ccagggttcg gcagcagata ttctcaagat
    16201 tgccatgatt cagctggata aagccttggt tgcaggtggt tatcagacta agatgctgtt
    16261 acaagtgcac gatgaaatcg tccttgaagt gcctaaatct gaattggtag agatgaaaaa
    16321 attggtgaaa caaaccatgg aagaagccat tcaactcagt gttcctctta tcgcagatga
    16381 gaatgaagga gcaacctggt acgaggctaa ataaaaaggg ggctagtcct ccttttttgt
    16441 agtagaattc tgcaaacctt ttcaaaatgt gctatactga tgaaaaagga ggattcctat
    16501 gagtcaagaa tttatcaatc caagtgatgg cgtgatacgt cagtatctcg caacgagtaa
    16561 aacccttgct gtggtgggtt tgtctgaccg tgaagaaaca accagcaatc gagtgacaaa
    16621 ggaaatgcag gctcggggct ataaaatcat cccagtcaat cccaaggcgg caggtggcga
    16681 aatcttgggt gaaaaggctt atgctagcct cgctgaaatt ccttttcctg tagatattgt
    16741 caatgtttat cgtcgcagtg aatttctgct cgatgtggcg cgtgattttc tcaaagctga
    16801 tgccaagatt ttttgggcac agctaggact tgaaagttta aaagcgaaag agattttgcg
    16861 tgatggtgga tgtgatgata tcgtgatgaa tcgctgtatc aagagagaac atactcgctt
    16921 gattgaggaa gcataagaaa aaggtagctg atgggctacc ttttgtgtta tactcaatga
    16981 aaatcaaaga gcaaactagg aaactagccg cgggctgctc aaaacaccgt tttgaggttg
    17041 cagatagaac tgacgaagtc agtaacatat atacggcaag gcgacgttga cgtggtttga
    17101 agagattttc gaagagtgtt agaaaatgcc gataagggtc tgcataccaa gagtggtgag
    17161 gatgatggca atccagcaga tggctccaag aagaatggat tttccactgg atttgaccat
    17221 agcgaccaga ttggttttga gaccgatagc actcatggcc atgacaataa ggaatttaga
    17281 gagttctttg agaggagtaa agaaactact ggacacacct agagaggtga gtagtgtagt
    17341 gaggagagag gcaaggataa agtaaaggat aaaaagtggg aagacttttt tcagttgcag
    17401 gctttgcttg ttttcttgtt ggcgactttg ccagtaggat agaaagagcg tgatagggat
    17461 aatggccaaa gtacgtgtga gtttaacaat ggttgcagac tcgagggtat tgctttggta
    17521 aagactgtcc caagcgctgg cggcagccgt tacagaggaa gtgtcgttga ccgcagtccc
    17581 tgcaaagagg gcgaagcctt cattggatag atgaagccag gtgccgaggg ttggaaagat
    17641 gagcgcagcc aagacattga agaaaaagat aacggaaatg gcttgggcta cttccttttc
    17701 cttagcatca ataacgggcg ctgtcgctgc aatggcagaa cccccacaga tagaagaacc
    17761 tactccaacc aaggtagcca gttttgtatc cagggcaaag aaacgctgga agaggtaggc
    17821 aataatcaga gctattgaga tagtggacag gatgacaggg agtgaagatt ggccaactgc
    17881 gaagacctgc gagatattga gaccaaagcc aagcaagaca acggcatatt ggagcaactt
    17941 cttggaacta aaggtcaaac cagcatccag ttgtttatag gacgagagaa agggatgtag
    18001 gagcatgcct atgaaaatgg caaaaacggg cgcgccaatc acagggaaga atcctcctaa
    18061 gtaccaagat acgatagaaa tgagaaggca ggccaagata cctgctccat tttttgatag
    18121 aaatgacata aaaacctcca aataaaatct attaccatta tagacctata aacaggaaaa
    18181 gtaaaataga aagtggaaag ctatcctcta atgtattttt gcggtcgggg ggcttttgta
    18241 gtataataga gatacgtttt gaaagtagga ggtatctatg gacttaacta agcgctttaa
    18301 taaacagtta gataaaattc aagtttcgtt gattcgtcag tttgaccagg ctatttcgga
    18361 gattcctggg gtcttgcgtt tgaccttggg ggaacctgat tttacaacgc cagaccatgt
    18421 caaggaggcg gccaagcgag cgattgatca gaaccaatcc tactatacag ggatgagtgg
    18481 tctgctgact ctacgtcagg cagctagtga ctttgttaag gaaaagtacc aactggacta
    18541 tgctcctgaa aatgaaatct tggttacaat tggggcgaca gaggctttat ctgcgacttt
    18601 gacggctatt ttggaagagg gagacaaggt acttttgcca gctcctgctt atccaggcta
    18661 tgaaccgatt gttaacttag ttggggcaga aattgttgag attgatacga ctgaaaatgg
    18721 ttttgtcttg actcctgaga tgttggagaa ggccattttg gagcagggtg ataagctcaa
    18781 ggcggttatt ctcaactatc cagccaatcc gacaggaatt acctacagtc gagagcagtt
    18841 agaggccttg gcagctgttt tacgcaagta cgaaattttt gttgtctgtg atgaggttta
    18901 ctcagaattg acctacacag gcgaagccca tgtgtctcta ggaacgatgt tgagagacca
    18961 ggctattatt atcaatggtt tgtctaaatc gcatgccatg acaggttggc gtttggggct
    19021 gattttcgct cctgcggcct tcacatccca gttaatcaag agtcaccaat acttggtcac
    19081 tgccgcaaat accatggcgc aacatgctgc ggtagaagcc ttgacggctg gtaaaaatga
    19141 tgcggagccc atgaagaagg aatatatcca gcgtcgggac tatatcatcg aaaaaatgac
    19201 tgctcttggt tttgagatta tcaaaccaga cggtgccttc tatatttttg ctaaaattcc
    19261 agcgggctac aatcaagact cctttgcttt tctgaaggat tttgctcaga agaaggccgt
    19321 tgcctttatc cctggtgcag cctttggacg ttacggggaa ggctacgtcc gcctatctta
    19381 tgcagccagc atggagacta tcaaagaagc catgaaacga cttgaggagt atatgagaga
    19441 agcatgattc agtctatcac gagtcaaggc ttggtgcttt acaatcgcaa ttttcgtgag
    19501 gatgacaagc ttgtcaaaat ttttacagag caggttggca aatgcatgtt ttttgtcaaa
    19561 cacgctggtc agtctaagct ggcgcctgtt attcagccct tggtgctggc acgatttctc
    19621 ttgcgaatca atgatgacgg actcagttac atcgaagact atcatgaggt catgactttt
    19681 cccaagatta atagtgacct ctttgtcatg gcctatgcga cctatgtggc agctcttgca
    19741 gatgctagtt tgcaggacaa tcagcaggat gctcccttgt ttgctttttt gcaaaagact
    19801 ttggagttga tggaaacagg cttggattat caggttttga ccaatatttt tgaaattcaa
    19861 attttgactc gatttggaat cagcctcaat tttaatgagt gtgtcttctg ccatcgggtt
    19921 ggtcaggctt ttgacttttc tttcaaatat ggagcctgcc tctgtccaga gcattatcat
    19981 gaggataaga gacgttgtca tctcaatccc aatatcccct atctgctcaa tcaatttcaa
    20041 gctattgatt ttgagacttt ggagaccatt tcgctcaagc ctggaatcaa gcaagagcta
    20101 cgccaattta tggatcaatt atatgaagag tacgttggga ttcacctaaa atcaaagaaa
    20161 tttattgatt ccctagcaga ctggggacaa ttactaaaag aggaaaagaa atgaaaaaaa
    20221 tcgcagtaga tgccatgggg ggcgattacg cacctcaggc cattgttgag ggtgtcaatc
    20281 aagccctatc tgacttttca gatatcgagg ttcaacttta cggagatgaa gctaaaatca
    20341 agcaatatct gacagcgaca gagcgcgtca gcattatcca tacggatgag aagattgatt
    20401 cggatgatga acctacgaga gctattagga ataagaaaaa tgccagtatg gtattggcag
    20461 ccaaggctgt caaagatggt gaagcagacg ctgtcctttc ggctgggaat acaggtgcct
    20521 tgttggcagc aggattcttc atcgtgggtc gtatcaagaa tatcgaccgt cctggactca
    20581 tgtctacctt gcctaccgtt gatggaaaag gttttgacat gctagacctt ggtgccaatg
    20641 cagaaaatac agcccagcac ctccatcaat atgcggttct aggttccttc tatgctaaaa
    20701 atgtccgtgg cattgcgcaa ccacgcgttg gtttgctcaa caacggaaca gagagtagca
    20761 agggcgaccc gcttcgtaag gaaacttatg aattactggc ggctgatgaa agtttgaact
    20821 ttatcggaaa cgtggaagcg cgtgatttga tgaatggcgt tgcagatgtt gttgtggcag
    20881 atggtttcac gggaaacgct gtgctcaaat ccatcgaagg gacagctatg ggaatcatgg
    20941 gcttgctcaa gacagctatt acaggtggtg gtcttcgagc gaaactaggt gccctccttc
    21001 tcaaggacag cctcagaggt ttgaaaaaac agctcaatta ttcagatgtt ggtggagcgg
    21061 tcttgtttgg tgttaaggca cctgttgtca agactcatgg ctcaagcgat gccaaggctg
    21121 tttatagtac gattcgtcag atccgtacca tgctagaaac agacgtggtt gcccagactg
    21181 cgcgtgaatt ttcaggagaa taaaagagat gacagaaaaa gaaatttttg accgtattgt
    21241 gaccattatc caagagcgac agggagagga ctttgtcgtg acagaatcct tgagtctgaa
    21301 agacgatttg gatgcggatt ctgttgactt gatggagttt atcttgactc tggaagatga
    21361 atttagtatc gaaatcagcg atgaagaaat tgaccaactc caaaacgtag gagatgtggt
    21421 taaaatcatt caaggaaaat agcaatcgga gttccaagtc aacggaagta gatggttttt
    21481 agaaatgaga aatatcggac aagctggtaa aatcttggct gacagtggtt atcaagggct
    21541 catgaagata tatcctcaag cacaaactcc acgtaaatcc agcaaactca agccgctaac
    21601 agttgaagat aaagcctgta atcatgcgct atctaaggag agaagcaagg ttgagaatat
    21661 ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
    21721 cttcggatta cgaatgaatt tgattgctgg tattatcaat catgaactag gattctagtt
    21781 ttgcaggaag tctaatagta aaaaagtgat tagaaaacat cttttttaaa aatagagatg
    21841 attttgaaac aaaaaagcta attcaagacg tttcgatgcc aattcaagat ttggatgaaa
    21901 aaaattaata gatactgtta tactaaactt gtcaagtttg taacaagaca aatattaaaa
    21961 ataaaaaaga ggtattcgtt atgaatacaa aaaagatgtc acaatttgaa attatggata
    22021 ctgagatgct tgcttgcgtt gaaggtggcg gatgcaattg gggagatttt gccaaagcag
    22081 gtgttggagg aggagcagta cgaggtcttc agctaggaat taaaacaaga acatggcaag
    22141 gtgcagcaac tggtgctgtg ggaggagcta tacttggagg tgtggcctat gcagc
//
LOCUS       DAVLUM010000033        21691 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLUM010000033 DAVLUM010000000
VERSION     DAVLUM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.033"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(114..338)
                     /locus_tag="VYN42_001139"
     CDS             complement(114..338)
                     /locus_tag="VYN42_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEV1462217.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLIFMVITYK"
     gene            complement(343..522)
                     /gene="asp4"
                     /locus_tag="VYN42_001140"
     CDS             complement(343..522)
                     /gene="asp4"
                     /locus_tag="VYN42_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEV1462218.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(524..1861)
                     /gene="gtfB"
                     /locus_tag="VYN42_001141"
     CDS             complement(524..1861)
                     /gene="gtfB"
                     /locus_tag="VYN42_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEV1462219.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPAVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(1854..3365)
                     /gene="gtfA"
                     /locus_tag="VYN42_001142"
     CDS             complement(1854..3365)
                     /gene="gtfA"
                     /locus_tag="VYN42_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEV1462220.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDEDKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(3377..5749)
                     /gene="secA2"
                     /locus_tag="VYN42_001143"
     CDS             complement(3377..5749)
                     /gene="secA2"
                     /locus_tag="VYN42_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEV1462221.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLLDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKEYHAKGNPLLVFVGSVEMSQLYSSLLL
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDMIYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWIEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(5742..6182)
                     /gene="asp3"
                     /locus_tag="VYN42_001144"
     CDS             complement(5742..6182)
                     /gene="asp3"
                     /locus_tag="VYN42_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEV1462222.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(6179..7714)
                     /gene="asp2"
                     /locus_tag="VYN42_001145"
     CDS             complement(6179..7714)
                     /gene="asp2"
                     /locus_tag="VYN42_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEV1462223.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(7698..9278)
                     /gene="asp1"
                     /locus_tag="VYN42_001146"
     CDS             complement(7698..9278)
                     /gene="asp1"
                     /locus_tag="VYN42_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEV1462224.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFVSSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNVVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(9288..10505)
                     /gene="secY2"
                     /locus_tag="VYN42_001147"
     CDS             complement(9288..10505)
                     /gene="secY2"
                     /locus_tag="VYN42_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEV1462225.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNDTYRPLI"
     gene            complement(10562..11467)
                     /locus_tag="VYN42_001148"
     CDS             complement(10562..11467)
                     /locus_tag="VYN42_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1462226.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGAAQVKNMGISVAKGEYITIVDSDDIVKENMIE
                     TLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFN
                     SSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRS
                     GSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLT
                     DTEEYKDICFRLKLFFDAEQRNGKS"
     gene            complement(11467..12663)
                     /locus_tag="VYN42_001149"
     CDS             complement(11467..12663)
                     /locus_tag="VYN42_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV1462227.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNSGVLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMAGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(12672..13892)
                     /locus_tag="VYN42_001150"
     CDS             complement(12672..13892)
                     /locus_tag="VYN42_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEV1462228.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(13923..16367)
                     /locus_tag="VYN42_001151"
     CDS             complement(13923..16367)
                     /locus_tag="VYN42_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEV1462229.1"
                     /translation="MNKTIVLAGDRNYTRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDTVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLTANRYRDLWWEFHDLEWSQILQHHMGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTNMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLERSVDLYLDINYSHVVGTILEDMKILEKPILSFDTTEHGNTGQLVFKKDEVSVMVQ
                     AIKDYRRDGRFLSCYEGSDFHCLTFTNSQELQKIDYLVKNFTMVTFHIAAWTVMGPML
                     QELAKKYKNVKLYPEVKSDQFEELKSQMDVYLDINLHNSTSEVVKEISSLNKPMLAFY
                     TSQNGNHGQHLYSSEHPERLLQAFHALIKGETLGEPEKPIKVIGIDQTLDYVIKNKSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFNKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(16377..17387)
                     /locus_tag="VYN42_001152"
     CDS             complement(16377..17387)
                     /locus_tag="VYN42_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1462230.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYLYMYNLSDILIVPSEQMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWFQDTPLRVFSNKGEASSNARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSNLSTAKFIV
                     DQGLGFMANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     ID"
     gene            complement(17541..18416)
                     /locus_tag="VYN42_001153"
     CDS             complement(17541..18416)
                     /locus_tag="VYN42_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1462231.1"
                     /translation="MENELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLESDYLE
                     VLYSKIVEYDTDFVIGSYKKFSMSDNCYYMHVWDQDYYEKIWTSQELLTQLPNLENYD
                     GSYTVSWGKLFKRFLFDEVLFNEQRRFGEDFECSFKLYLTMTSCLYIHRALYNYRVHS
                     ESMVGKVKTERQLMDDVEIRLGRIPFLIGRGIDSTPYIAEIKRLIQWRLDTKSDVEEG
                     ESNALCMYREILRNL"
     gene            complement(18456..19334)
                     /locus_tag="VYN42_001154"
     CDS             complement(18456..19334)
                     /locus_tag="VYN42_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEV1462232.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLSNICFHIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            complement(19331..21415)
                     /locus_tag="VYN42_001155"
     CDS             complement(19331..21415)
                     /locus_tag="VYN42_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1462233.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIITQTYKNIEIVVVNDGSTD
                     ASGEICKEFAEMDHRITYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIELDYVET
                     LYKKITEYQADIAVGNYYSFNESEGMFYFHISGDSYYEKVYDNVSIFENLYETQEMRS
                     FALISAWGKLYKARLFEQLRFDIGKLGEDGYLNQKVYLLSEKVIYLNKSLYAYPIRKG
                     SLSRIWTEKWMHALVDAMSERITLLANMGYPLEKHLAIYRQMLEFSLSNGQASGLSDT
                     ATYKEFEMKQRLLNQLSRQEESEKKAIVLAANYAYVDQVLTTIKSICYHNRSIRFYLI
                     HSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFVQEDK
                     ALYLDCDLVVTKNMDDLFATDLQGYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKK
                     ENMTQKLIDLTNEWHNKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEG
                     QDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKE
                     PFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYL
                     VDVDNELVETSQVLLDINHGEKTEEILDQFANLGKPILSFENTKTYEVGQEAYAVDQV
                     QAMIEKLREISK"
     gene            complement(21476..>21691)
                     /locus_tag="VYN42_001156"
     CDS             complement(21476..>21691)
                     /locus_tag="VYN42_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1462234.1"
                     /translation="SASASASTSVSNSANHSNSQVGNTSGSTGKSQKELPNTGTESSI
                     GSVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT         6962 a         4618 c         3302 g         6809 t
ORIGIN      
        1 cggtgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaaaaagaaa acttcagacc aatccacaaa aggtgaatat ctgaagtttt cttttattta
      121 taagtaatca ccataaagat taatagtaga acaaataaag ccaaactcac caataaagtg
      181 agcaccttga ccaaggtgtt gctctgccag tagcttggtt taccaatatt actagtggca
      241 tccatggaaa atagttgatt ttgacggggt tgtatagtta ccaatacaat caaagcaaga
      301 gataggataa tagctaaaac aattagtatt tcaatcatag atctacctca aaattcccag
      361 caaagtaaag agcaaaccaa tcagaatcat caaacccagt aaaagtgaaa aagtcttact
      421 aatcttttcc cctcgggttt ctttttcctt cttgatgggt ttttgtttca actcttccat
      481 gcggccttca acgtctttgt aaaataaatc ttcctctgac atgttagcct cctaaaacag
      541 tttgcatggt ttcctgatat ctcaccaagt caacataatt tgcatgttgg ccttgtttgc
      601 caagtgcctg acgcatttga tcaacatctg aaagggccaa tttaatggtc tcaaccaaag
      661 cagcaacttc actactttca aatagatggt ctggagcgat ataaagtcta ttgtgcaccg
      721 tctgattaaa gccaagaatc aagagattgt gctcaaaggc ctgacgcact gcctgtagta
      781 actcattact gtggtttata tccaagtaaa tatccgacag ttgatacagc tcctgaatct
      841 tctgtggact agcattctgg taaaggacca cattaggata gcgaagcatg tctaagagct
      901 tagaagacat ctctgtcacc gctgcaatac ggaaagtgac agcaggcaag gctcctgcga
      961 ttgcttctac ttgctcaatc tgatctgaat tggtcaagat taaggcatct cgtcttagga
     1021 aattatcacg tttgaactgg taatgataac ccaagtgcac aaactgatca tggtatttct
     1081 cgtcagttaa ctctaaagcg cgctcataag tcgccttatt tggaatgatg atcttcttag
     1141 tacgcacatt atcactttcc aaaatcaact gcatattacc tggaatggca tcatagagag
     1201 gttcctgcca taccaagaca tccgagccag atttatctgg atgatggaag gaaaccaaga
     1261 aaggagtcgc tagagtatta aagataagct gactggtatc tatttccaaa tcttgcaaaa
     1321 agaaggtgat aaattcaact ttatttgcaa agtaacgcat ggactgacca ggcaaagtca
     1381 ataagatatc acccgtcaca tggttttcca gtaaaacttg ttggccattg acatcttggt
     1441 aaactgtcat aatcggctcg ctatctgcgc tataagtggt tttagcaaag caagcaccaa
     1501 agcgattgta gtggtcaacc tgacgtactc gaccttctag gtctttccag tctacctgtt
     1561 taaccaagcg agcctgcatt ccatcaacat aatgaatgac agccctctcc tgcgtcacat
     1621 cttcaataca agcagactga ttatctccta aaatttccca aaaatctgaa acgggaactt
     1681 ggttaaaata gagaggtttt ccatcctcgt aacctagata ataggtaaaa ggagaaagca
     1741 gaccatcagg cagaaaacca tctgcatcga tgaccactcc aagttgagaa agaccagtag
     1801 cgactagact ttcatgtaaa tctcgacttt cttgactgta actatcataa agttcaatca
     1861 tggagcacct cctctactgt tttcttccac ttttctaaaa tttctttggt caagaagcct
     1921 tctgcaattt gataagaata ggcacgcata gcttccaaac gattttcttg atacaattga
     1981 caaatcttag cggcataagc ttgcttgatt tggtcttcta catggtcaga tgaacttgga
     2041 atcaaataac cattttgccc atcctctata aaggtctgat taccataagg cacatcaaaa
     2101 ccaattagag gtagacctga accaatagct tccatcaagg tcagaccaaa tccttcgctg
     2161 gtagaagccg ttaagtagac ctcatactgg ctataaatct gcgaaagttc cgcatgcccc
     2221 ttgagttgga tatagtcctc tgcctgatga tttgcaataa tttctctaag cagagaatct
     2281 tctccaccac taccatagat atcaaaggtt agttccggta actccttatg agcttcaatc
     2341 acagctttca caagccaatc aatgtgcttt tctttggcaa gacgtgaagc cgtaatcaat
     2401 gaaaatggtt tgcgcccttg acttgaatct gtcaaggaat caatactgcc tacaggaatg
     2461 gtaacaatct ttggctgatg ctgagtatat ttggcaaatt gctcttgtag aacttcattt
     2521 tgtctatcag tagacacgat aaagaagtca accttatctg cattggtaaa ctgatagtca
     2581 taatagttat tccaaaggat atagtcctca tttgtagcat tttcactata atgctccgca
     2641 tgaacaacta ccgctagatg tgctgtctgt gcttcctcaa acacaacctg tccaatacct
     2701 gtctccctat ccagaataac caaatcagac ttgttcaaat tcaaagattt cataaaggca
     2761 cgcacaaaag cttgctttcc atagaaaatc ttatccttga aatgataaac ttcttccttc
     2821 ccttgattca tcaagatatc atagactgga gtcccgtctt cattgtaaaa agttcgttgg
     2881 tataagactg caacattgtc cttgggagca aaatactcgc tacaataacg cgtataagaa
     2941 aagtaatcct tccgaatcag gtttccctta aaaacatact cggcatgttg aaccaagtcc
     3001 ttgtcctcat ccaccaaata acaggttaca aacttatctt ggtcaaaaaa gaagacacgt
     3061 aaaaccttgc catttttttc tctgtgactt tcttcaccac caaagtaagc caagacatca
     3121 tccactgtca cgctagtagg cgcaattttg atgtctgtga aatgattata aagccagata
     3181 acctgattat catcaaaacc aatattggct gttaagtgct gaatattatc ggctaaaatc
     3241 atatctgtaa agataaactt agaggacaga tttaatttcc gaaaaacacc agcacgatag
     3301 gcttgagcgt attcaacacc gctactagcc caaccaattc ctaaatttat attgtaaatt
     3361 gtcatatttt ctcctcttat ggaaaatgag tcacgatttc accttttgga gtgacctcaa
     3421 ccagccccat caggagatta cgcaccatat ccgcacggat ttgttctttc atagcttcaa
     3481 agcccgcgta ggcttcttga tagtactcta cgattggatt tttctgacta gcagattgac
     3541 caccgatagc catggatagc tgttgtagat agtctacctg ctctatccag ttgtcatcaa
     3601 tggctttaag cagtgaaagt cgtaaaaact gttcatataa gtcatgttga ttaagtaatt
     3661 ctttcttttc agaaagttct ttatcaatca cctgcttcat aaagctacga actgcagttt
     3721 tgtcagttac atctatataa tctggaacct ctttaacatg aaaactaata ttggtcacaa
     3781 taaagtgaaa cagtaattca cgactagcat agtgatcagc cgctacctct tctgtatatc
     3841 tctcaatgat atccacaaca acatcctcta agtcacgaga accatctatt agacgattac
     3901 gctccttgta aatcatatcc cgttgaatat tcatactttc agcatattct agagtctgac
     3961 gacgtgccga acggccagca ctatcactag catgttgagc cttttcgact agtttccggt
     4021 atttacgacc tttcaatact tccggttgag tcatatcttg aacctgatag tctttgtact
     4081 ttttatgcac ccaagatgga ccaaatttct tgataacatc atcctctaag gatacaaaaa
     4141 atttactcat accaggatct ccctgacgac cagaacggcc acgaatttgt aggtcgatcc
     4201 gctgactttc catccgctca gtcccaataa caatcaagcc cccaagctct gcgactcctt
     4261 taccaagctt gatatccgta ccacgtcctg ccatagaggt agccactgtc acagccccca
     4321 tctgacctga ctcggagata atctgagcct cacgcgccgc attattagca tttaaaacat
     4381 tatgggcaat tccctctctg agcaagagtg acgaataaag ttgagacatt tcaactgagc
     4441 ctacaaaaac gagtaaagga tttcccttag catggtattc cttgatgtac tccaaggatg
     4501 catacacttt ttcaggtaaa gtgatatata gattatctgg atagtcaatc cgttgtctcg
     4561 gacgattggt tggaatgcgt actacagaca tattgtaagt ttcaataaac tctttttccg
     4621 cgaccttacc tgtccctgtc ataccagata ttttattaaa catcttaaaa agactctgat
     4681 aggtgatcga ggccatagcc cgcgtctcag gagataattt gacatgttcc ttggcttcaa
     4741 tagcctgatg gagacctcct tgaagtttag tcatttccat tagacgccct gttcccttat
     4801 caaccagtac catctcattt ccacgaatga tatagtcctt atctttagta aagagcttat
     4861 gagctcgaat cgcataaacc aaatgacgag caaaagacgc atgctcttcc ttgtataaat
     4921 tatcaatccc taggaaattc tcagcagact tggccccctt agtagtgagc caaacctcct
     4981 ctttctcctc tttaaagata taatcctctc cttcgaccaa ggttgttaca agtgtatcaa
     5041 tgatcgcata gtaattagac tgaacacgag gagaacccgc aataatcaga ggagtttgtg
     5101 cactatcaag caagatatca tcaatttcat caataatcac atagttaaac ggtcgtaaaa
     5161 acttaccttc ttcattcgag gctaggttat catttagata atcaaaacct aaattactat
     5221 tggttgtgta gatgatatcc gaagcataga taagcttctt ttcttcagct ttcatctcct
     5281 tctttggatc ttccgtaaat ggtacaccaa tggtcaatcc tagaaaacga taaacttggc
     5341 ccatttcctc ggcatcacgc tttgataaat actcattagg agtcacaacc atcactcctt
     5401 ctcctgaaaa agcgttcaaa tagacaggca tggtagctgt caaggtctta ccttcccccg
     5461 tattcatctc agcaacattt ccatagtgca tgacaatagc tcccatgact tgaacatcat
     5521 aggggaacat ccctaaaatc cgcttatctg cttcacgcac cacagcaaaa gcttcaacca
     5581 aaatatcgtc tagactttct ccctcggaaa gacgctgacg aaactctact gttttagcta
     5641 ctaattcttg atccaaaaga gaggacatct tgcctttcag ggcattaatc tgctttaaaa
     5701 tctttttcac tttcctaagc tggaaatctt gacctaaacg tctaaacact tctgatctcc
     5761 ttgatagaaa aatgataaaa agttaaggac tcaaatccag cacttaaaag agaaacttga
     5821 taagtataac tatcttctgg ataagtaaat atgaaatctt tcgctttttc tacctttttt
     5881 tctaaaatat caccatagcg gtcaaaaaaa gttatcttgg tataaactcc attttcaggc
     5941 tggcaatcaa aaaccagtga tagttgatac tcctgctttc tttttaataa gggaagctga
     6001 ggttgggttc gtgcagcctg gtaattgaca ctagaaaacc aagtctttag aatctcacca
     6061 gatggcaata gaggattata cagacgaaca cttttgtcaa ggtaataaga tacagttgtt
     6121 ccatacatat aagtcccacc aacttctccc caataaatag actgtctctg tgtaataatc
     6181 atcttttctc ccttccaaaa ccagtctcta agaccattct ataaaagtgc aaaaaccaag
     6241 aaatattggt atctgtatca tcattgtgtc gtccagcagt tcctttagat aaaatcttcg
     6301 cacctgtatt acacagataa gacactaatt gttcataggc ttgtggatcc atttcttcat
     6361 ctttcatata ggataaacca aaggttgtct ttgaaaaatt tgcttgttta aaaattttcc
     6421 aaaaacgctg atccaactcc gtcatatctt gagaacttgt cccacctgta tgatgaatta
     6481 aacaatcaaa agctaagtta gagacacccg gtgcgtccaa acgtccacga ctagctatag
     6541 ttcctaaatt agccaagggc ttaccaacta tgatggcatg gggttcaaaa gaagcaccat
     6601 aatagagagc cggaaacgtt cccatagaaa gacctgataa aatcaaatcc ttatgatcaa
     6661 agcctaaata atcaagatag tgagtgatcg tatcctttac ttttccctct agctcatccg
     6721 ttccgagata aaaagctccc ccctctaaac gtggatcaga aaataaaatg aagggacatc
     6781 caagagtttt catcataaag taaccctcga atccttctgc aggtcgataa cctgcaaaat
     6841 agacagtcaa aggcggttta aaatcacctg gatggaagaa atagtttatt tcatcacgct
     6901 tggaatcatg taggatattt ccaccaagta caaacttacc aaattgtttt cgactccatc
     6961 gttggtgaag attacctagt ttgatagttc cacgacctct tgcttcaaca gatatcgaga
     7021 gaaagtagtc tccgtctcga ctatccataa aaagtgcttg ctccaagtct ttttcagata
     7081 ctattacttc ttcaaagaaa tcatcaacag acccactcca cattttacgg ataaccaaac
     7141 gaaagtcaca attaccttcc ttctcatatt caagccacaa ctcaataggg agtgtttttt
     7201 gcaccataat attataagcc caataggcaa gctgggcaaa atcttgccca aactcacctt
     7261 ccaaactgac ataatccaat ccttgataag aaatagctcc tgtaaaattt ggattgactt
     7321 gtatcgtcgg aggaaagagt ttatcaccat acccaccgcc aaaaagagat ttacttaaat
     7381 cattgattaa ttgttgggga cttaaaaaat caattgcttg tgcacatcgt ttttttagaa
     7441 aatccacaac ctctctatca tttatttgta gattctggtt atagaacaaa gtataaggtt
     7501 caaaatattt tacataggaa aataagtctc tggaatactg accatcttct attaaaactg
     7561 catgaaaacg gttaatatct tctttttcga ttatttcacg aagggctttt gatgagtttg
     7621 ggtaaaaata ataccaactc atattttcag gtatgtcata gtgattttcc caattggcaa
     7681 gtcctatctg taaaatatta agttcctttg acatttttaa cctcctctat ccatttctct
     7741 aattttccaa gaaattgttg tcctgtgtgc tccttaatct tatcaattga atatatcaag
     7801 gactcattcc actccttcaa cctatctgtg taataatgtg cagccttaga aaattctgta
     7861 acatctgcta acaaataacc attttttaaa tgttccacat agacggtttc aactaggttg
     7921 atttgaggaa ttcctgcact aatcccagca atctgtgtgt agagatgagg atgtctattt
     7981 aaatccacaa tcaaacggac aaattctagt gtttttatca aatctaactc atcattcaag
     8041 ttaacaaact gtaagcgtaa gtcctggtgt tgattttctt ccagaggatt ttctgcatca
     8101 ccataatcaa tcgcctttcc caggttttcg gattgaatgt tttcttggat gaaagactca
     8161 acaatccctt caaccacatt catttgctcc tgactagcag caaaggctcc aaaaatcacc
     8221 tcagtatcct tattttcagc gacaaaggac aagacttgaa gcagagcttg attatcaatc
     8281 ccctgctcaa aatccagttg aaaataaatg atggattctt tcttagtttg gcttcgtccc
     8341 aatcgtaatc gggtgtcaaa agatgataaa tgataacatt gatgcattcg ttcaggatac
     8401 aactcctgca acaatcgtaa actatcctct ctatccacca aaatcaaatc cgatttttca
     8461 aaagttacat ctaaatccct aaaggtatct tgaggattac gtccaatgaa cagactcaac
     8521 agtttaggat tagtactagg taaacgatct agtaccaact ggtcatgatg agaatgagaa
     8581 ggaagcataa aaatatcctg atccttcaca tacgtttgca gataattctc aaaaaattct
     8641 gccaccagat ctcccatatt ttgataggta agcattttaa agcgataacc caaaattgga
     8701 ttgacttcta cctgtcctcc ttcttttaaa cgctctctaa attgccaaac tcccttagga
     8761 ttcaaatatt cttgataggc tgcttgccca tcttcaaaaa agataatgct cgatacaaac
     8821 cctcgatcat ccatgatatg gtgcatatgt atttgaccat tcggttcaaa atactgtata
     8881 tcactgatga agccttcaac tccatgttca accttagcaa atttcttccc atttttttga
     8941 acgataatcg taaagggact ataaataaat tcacagtcat catcccactc aatatctcta
     9001 atgcttaaaa cttgggtatg gagattatga aaatcttgca taacatcaaa aacggaataa
     9061 gtatccgttt ctaacacacc atgtctatat aaaaaataac gtagatgagg ctggtaagct
     9121 aatactaata gacgagaatc tatatcttgc tcttgaaaga gccggatctg gtgaaaggta
     9181 tcatcaaact ctagacgaaa atgagaaaaa taccatggag tgatatctgc atgccatgtt
     9241 ctttctgacc cataccaagc tggaataaaa taatacataa aagtctccta aatcaagggt
     9301 ctataggtat catttagcct taaagccttg acctcgtctc taatcgtaaa aatcatgccc
     9361 ccgaacatca taaataagcc tggaatcatt gccaatcgta ataacttttc atcaaacaaa
     9421 acaaaaagca tgggaccacc tgccataacc acattaaaga gaccacctat gactgagaaa
     9481 cgaaggacca atcgattaat aaatcgacta gtatccgcac ctggataaat accataaatg
     9541 tattctccag attttttcat acggtctgca atctcttctc cattcatcgt aacaaaagca
     9601 aaaatgatac taaataaaaa taagaccgaa atataaacat agacccacaa aggctttcca
     9661 atcataaatt cctttgataa agccgctaac cctgaatgat tagggaaaat aaatcccaac
     9721 aagatgaaca aataagctgg tacactaaga aaactcatca catacatata aggcatccca
     9781 cctgcaggat tcaacatgat ttcgagataa aaatagcgtt taaatcgatt gtgtaagcca
     9841 attttattaa caggaaccaa atagcgagct cgatacataa gggcaagtaa ataagaaaag
     9901 acaagggtta ataaagcaag taacacaata atccctgttg gaatgtgtac tgtctgaaat
     9961 gtttccaaaa catcctgagg aatatttaaa accatactgg ataggagaat gactatagaa
    10021 cctccaatcc ccatactcgc atttaaatct gacaaccaaa caagaaaaaa tgttcctgct
    10081 atcagcaata ttgtattcat tagaacaacc aatattgcag aataggagga ttgtactggc
    10141 agtctcaagc taactgccaa tgattgaatg acagctatca tcaaggtcag gtacatttta
    10201 cggcgatctt gtatttctat agacgtagat gttaaaccca accgtttaga aaaagaaaac
    10261 atctgccata aaatcatagc tgacatccaa ggggacaatc caacagaaaa aattgacaaa
    10321 cttcttagat ttccacctgt tagggcggct gagaatgcta gataggctgt tgaacctcct
    10381 aaaaaatctt tagtatttag gtcaacaaaa gggagagtaa tacgacttcc caatacatag
    10441 ataaacagta gaaataaggt aaatagtcct ttttttactg ctattgacga ataaatctta
    10501 gtcataaaac actcccctca ccttcattgt ttgtgatatg gtaaataaca attcttttat
    10561 ttcaactttt accatttctt tgttctgcat caaaaaacaa ctttaatctg aaacaaatat
    10621 ctttatattc ctcagtatct gttaattgat ggtattctaa agtttgctta taatctttta
    10681 aaagattgac aaatcgaata cgcagaacgg agacatccaa accagccaag acacaatccg
    10741 atattttctt agaaaacact tcaacaatat ctcttgccca ggaaagatca aattccgttc
    10801 tcatgatgct tcctgaacgt cttctataca gatagagatt atcgtttata aagacgattt
    10861 tagaggctaa aagataaaag cgatgcatag ttgcttcatc atcaaagcgg cgaccatttg
    10921 aaaagtgaac ttcattgaat aattcttttt taatcaactt aaatgtcggc aatataaagg
    10981 ccgagctatt gaatttccaa tctcctgctt gacggttcat aatttcttgt atagctaatt
    11041 cttcgacgca aaaatcttgc cctgttacat aaaaataaaa attcccgtca ctttcgtcat
    11101 aattatagta attccctata acaacatctg catccttttc ttggacttgc tgataaagag
    11161 tttcaatcat attttctttt acgatatcat ctgaatcaac aatcgtgatg tactctccct
    11221 tagctacact aatccccata tttttaactt gtgctgcccc ccccttattt tcttgatgca
    11281 atactcgcac acgattatct tgcatcataa aagcatcaca aatttcccca gaattatccg
    11341 tagaaccgtc atcaactaaa ataatttcta tattttgata ggtttgcttc agaatatgct
    11401 cgacacactc cactaaatat tttcccgtat tgtatatcgg taccacaaca ctaattaatt
    11461 cactcattac tctatctcta tattcttcat tctatccact aaatcatctg gtctctccac
    11521 agaaaaaata ccgtcataga gtccatcatc catactttta cgtgtgatat caaaagcgaa
    11581 gattttcttg ccactttctt gtgcccttgt aactacatta aaaacctctc cacctgtatt
    11641 aatatctaaa taaactatag aatcgtccaa tagccaatca attctactat gtaatacatt
    11701 ttgatatact gttacattcg tatactgtga tagagaggtc agctcctcag aacaatcaca
    11761 cggtgcagcc aaatgaaaat gccaatcagg taaccgttgt actaaatact ctaaatgttt
    11821 tatatctgca ctccatgtca caagcatcac ttgtttttta gactgattgc ttctttcaaa
    11881 ataatttaaa tcggaacgtt gaaaagcaat ctctgaccaa tccaaatctc tataaaccca
    11941 ccataattca cgtagtctag atatactata tgtattccaa ggtttatcat gactagcata
    12001 gtgaacaatt gtaggtggat tgtcatctag acgttcacat tcttgagcaa ggtgataaat
    12061 atcaacaccc gccatataat tatatgtttt atctaaggct agccaattat cctcaaaata
    12121 aatatttaaa atactctgat ccccaagatg aacaacttga ttctgctcgg ccgctaattc
    12181 caataaacta ttgacaatag aatgttcttt ccactttgca acatccatta ataaaactcc
    12241 agaattaaat ccagattttc gtccttcata ggcatagaca tcatcaacag caccaattga
    12301 atatcctttg agatctatct caaacaaagt agctagttcc ccagttacaa tgatatcgga
    12361 atccagatac aataccctat cagattcaac cacttctgtc gcaaaaaatc taaagtaaga
    12421 agcataattt atatgaggtc ctgttttata gctttcaaaa agttctttat caatgtgtac
    12481 actgcgaatt gtagaattca caacttccat ttttctcccc aataatttaa accattcagg
    12541 agctatatca ctgttgagaa tataaaaatc aacatctcta ttgtgataca atacagactt
    12601 tatagtcgtc tctaaaggaa taagataggc attatctgcc gctaatacta ttgattttct
    12661 catactgttc tctacctcat gtaagatctg attgctgcaa ccattttttt cggaatggag
    12721 cttggataga taccttcata tgaaatctca gaaagatttt cagagcaagt attgtcgaaa
    12781 gctatcattg gttttttgta cttaagcaca aactcatatg catcttctaa ttttcgatca
    12841 tgattcaaat ccaaatacaa atctgaagct attactattt gttccaataa cattggtaag
    12901 gaatttggat atacggtaac attaggaaaa cgcgttaaag ctagtagttc atttgccata
    12961 tttgtataag caacaatatg aaaatgaact tctggcaatt gctccgccaa ataatcgatt
    13021 ttctcgacac accaagaatt cgttaaatta acacattgca acttaaatat ttgtgattta
    13081 ctaggatact tcacactctt tgaaaaccat tcatttaaaa taacagacca atccatcaaa
    13141 gagtattccc accaaacttc tcttagacgt ccaacagaaa attgattcca aggcttatcc
    13201 tgagaaatat agtgtaaaat tagtggcagt ggttcgagcg gaatatcaaa aatgaattga
    13261 tgtttaaagg ctgccgcccc ataatcatat cctatttgaa aattatattg atcttcaagg
    13321 gaactatatt gatctttaaa caacatattc aaaattgact ggtctccttc ttccacattc
    13381 tcatgttctt tttctgttaa gtcaatcaat ttttgtcgaa tagtttcaga tccccatttt
    13441 ttgttgttaa tcaagagaac accagcattg aagccgactc ctgccccaaa gcaagaacga
    13501 gctgctgcca aataattttc acctaagtct aattcaaaca aatcggtcaa atcaccagtc
    13561 acaatcaaat cactatctag atagagaact ttatcttctg ttacaaaatc tggaataaaa
    13621 tagcgtgcaa atgtcatatg attgatatga ggtaatttat tagaccaatt catttgaaac
    13681 tgtgagccaa ttaacttgca gtcaatcaag tcgcccccca tctcttgtaa atatattctt
    13741 atttgactaa accattcctg aggaatgtcc tgatttagca gataaatttt caaatgacta
    13801 ttgtgtctac agagtgactt catcgccgtt tcgatttgtc gaatataagc gtaatcacct
    13861 gcaaatacta cagcgcgttt ggtatttctc attttaaatc cttatcattt attttaaata
    13921 gtctagttta atattcgtgc aacaatctga ctgttatagg tttcatcatc aataaattca
    13981 atatcttggt cgaaattatg ttctgcagta tgtttatgag aaaatttaac cttagtttta
    14041 gctcccattt tcatccattc atactctgag tcaatatggc ctacatccaa aacttgatag
    14101 cccatctggc atagattata actcagaact tttgctgtag gacccagcat acataaaatc
    14161 agtcttcctt cagcatgttt cataatttcc tcttgaatgt tatcgacaac ggaataagca
    14221 ttatgagatg gacaaataat ccttttcaca gatttgacct tattaaataa atcatttcca
    14281 accccagagc gagatgtaat cccctctaca atcagaatat ccctattctc ccaaatactc
    14341 tttagctttt caaattgtcc ttttgcctta ctcttatctt cataatcaat gtatggacgc
    14401 gagataaagg tagagccata ccatgaaccc ttacacaact ctttataaaa atccatataa
    14461 acattcatat gttctttcca gaatggtgta gcccaccaag taaagacaaa acgatcgtca
    14521 aaagcatcag gtaaacaaac cactaatttc tcgtcactct caagacccac aatatgtttt
    14581 aattggttag ctaactctag atcatgattt tgataaggta taggcaaacc ccacatcaaa
    14641 ttgacttctc cgtctccaaa acgaactaat gaggacttat ttttgataac ataatccaga
    14701 gtctgatcaa ttccgataac cttgattggc ttctctggtt ctcccaaagt ctctcctttt
    14761 atcaatgcat gaaatgcttg aagaagcctt tctggatgct cacttgaata taaatgttga
    14821 ccatgatttc cattttgtga agtataaaat gccagcattg gtttattcaa tgatgatatc
    14881 tccttgacaa cctcactagt agaattgtgt aggttaatat ccaaataaac atccatttga
    14941 gatttgagtt cttcaaattg atcgcttttc acttcaggat atagcttaac atttttatat
    15001 ttttttgcta gttcttgtaa cattggtccc ataactgtcc aagctgcgat atggaatgtt
    15061 accatagtaa aattcttaac aagataatct attttttgca attcttgaga atttgtaaat
    15121 gttaggcaat ggaaatcact accttcataa caacttagga atcttccatc tcttctgtaa
    15181 tctttaatcg cttgaaccat gactgaaact tcatcttttt tgaatactag ttggccagta
    15241 ttcccatgtt cagtcgtatc aaatgataga attggctttt ctaagatctt catatcctct
    15301 aaaatagtac ctaccacatg actgtagtta atgtccagat ataaatctac acttctctcc
    15361 agcttatcta atacaggagg aacaatttgt ggatgcaatc ttacattatc atacacagct
    15421 aattttatca gcttatcacc catattcgtc caagccgcga tatgaaatac cacatcaggt
    15481 agagctgtaa ctagctcttc tatcccttct aaatcttggg aattcgttaa ggttaagcaa
    15541 gaaaattcct tatctagagg cgatattagt tcaaattctc ccatatggtg ttgtaaaatc
    15601 tgactccact ccaaatcatg gaattcccac cataaatcac gataacgatt ggctgtcaag
    15661 gtggtccagg gttttctgta ggtcgtaaaa tgaatcacca ctggtttatc attaaaagcc
    15721 agatgttcct gccaattgtt atacaaagcc acaatatcat gccctacttg taaattataa
    15781 gctcgaccta gttctaacca atcatcttgc aagacttgat tgaaaatcgt ttgatcacca
    15841 ttaaaatgct cgaaacggcc ttcttcaact tccttcattg taacaatgct ctgttcaatt
    15901 agtcgttctt ttaatttctc ttgacgccat tttttattgt tgattaataa aacacctgca
    15961 ttaaatgtaa ttccatctgt atctttaact gctgcgagtg atttttcttc taaacaaata
    16021 ctaaataatt tctctaaaga agtatttaca atcaaatcac tgtctaaata taaaaccgta
    16081 tcttcttgga tataatctgc aataaaatat ctagcatagg taatgctact aatgtggtct
    16141 tgcttttccc aatcttgaaa cacagtttgt tcaggtagct tcacatcgat aatctcacta
    16201 cctaacatgc gagctatttt tcgtggcttt cgaaaccaat ctggcatgat atcttgattt
    16261 aaaatataaa tcttaacatc tcgattgtgg tatagaatag attttatggt tgtttctaac
    16321 tgcctggtgt aattacgatc accagctaat acaattgttt tgttcatttc actcccttaa
    16381 tcaattccca agtgataaat cgcatctacc aatagctttt tagtgaaata accttctttt
    16441 agcaaataac taaaggtttt tatccgattc gtcatttctt gatattcttg tagattcatt
    16501 ttatcaacta tctcatgaac ttcctctaga ctattcgcca taaaacctaa gccctgatct
    16561 actataaatt tagcagttga taagttgctc ggtacaatga ctgggatgcc cgctgtcaga
    16621 taggtactaa ccttatgaga tatatttaaa gtatagtatt gattgctttc tccgtcattt
    16681 tgatgggttc cccagacaag accaaagcca ccttttgata attctagcaa cagttcctca
    16741 tcttttttcc atccttcaat gctaagattt ctagcattgg aactagcttc ccctttattt
    16801 gaaaacaccc tcaaaggcgt atcttgaaac caattttgta agtctggaaa acgctctaaa
    16861 cttccagcaa aaaaaagttc ttttttaaaa gcaggggtgt ataaggataa atcatgagga
    16921 tgatcccaca tcccttgaac aagaatcttc ttagtcgtca atccttcttc catcaggcgt
    16981 gttttcatct gttcagatgg aacaatcaaa atatccgata gattatacat atacagatag
    17041 tctttcatga gatagtaatt actatcaaac atgaggggaa caacatcatg gataaaacaa
    17101 ataattttca cctgcatatc cttcagctta tcaaacaaga gacgatcaaa ctcaaagcca
    17161 ttccaagttg gagactgaaa gactaagata tcaccaatag agatactggc cataatacca
    17221 tccagacgct tattcatttc agaaggacta tctgaagcaa tgttgtaaaa ataaatacca
    17281 acctctctaa atcccagttg actagctatc ttttgaacag cattttgagc taagataacc
    17341 gtactatcac cagccatgcc gtataaattt gttaaatgta gtttcatatt tcttatcttt
    17401 ttaaaattca ctttaagaat agaaaactct ttttctttaa tctgattttt agaatttcta
    17461 ttatagcaag tttaaataat gattatgatt ttatttcata tcaacagcta tcattttcat
    17521 ttaaatactg atattatttc ctataaattc ctaagtattt ctcgatacat acacaaagcg
    17581 tttgactcac cttcttcgac atctgatttc gtatctaaac gccattgaat aagtctctta
    17641 atttctgcta tgtaaggagt cgaatcaatt cctcttccaa tcaaaaaagg aattcgtcca
    17701 agtcggattt ccacatcatc cattagttgt ctctctgtct taacttttcc caccatcgat
    17761 tctgagtgta ctctataatt ataaagtgct ctatgaatat ataagcagct agtcatagtt
    17821 aaatacaatt taaaactaca ctcaaaatcc tcaccaaatc tacgttgctc gttaaataat
    17881 acctcgtcaa ataaaaaacg tttaaatagt tttccccaag aaactgtgta agaaccatca
    17941 taattttcaa ggtttggcag ctgagttagc aattcctgac tagtccatat tttttcataa
    18001 taatcctgat cccaaacatg catataataa caattatcag acatactaaa ctttttatat
    18061 gatcctatca caaaatccgt atcatactct actatttttg aatatagtac ttctaaatag
    18121 tccgattcca accaatcatc agagtctaca aaagtaatgt acgccccccc cgaacattca
    18181 atacctaggt tacgagctga tgaaagaccg ccgtttgctt tctcaaaata tttgaaacga
    18241 gaatctttct ctacaaattc ttcacatatt ttggatgaat gatctggaga gccatcattg
    18301 attaataaac actcaaaatt ttgatacgtc tgattctgaa tgctatccaa acacattcgc
    18361 aaataattct caacattgta gattggaact acaatactaa ttagttcatt ttccatatac
    18421 taactttcct agacttgatt tattctattt ccctcttaat ctcttctctt tacaacaaga
    18481 tttccattat tataaactac actgtttgat ggaatatcat tgcgtatgag acaacctgct
    18541 ccaataatgg tattatcccc aatcgtcact ccttttaaaa tcgtgacatt acttcctatc
    18601 cagcagtctc tgccaactct aatcggcgct gtagtccact gccacttttc aatcttttca
    18661 gcagtataaa tatggtcgtg atcataaaaa cgaacaccct ctcccatcat ggtaccagct
    18721 ccgatttcaa ttctttccat acagttaaaa ctacaagagt tgttgataaa aacaccatca
    18781 tgcagtatta acttaccaga agagacatga aaattttcaa aatttctaca gatgacattg
    18841 gctcctacaa tgaagtgagc cttatcatcg attttaaaga cattccaagt cccatcttgg
    18901 atgatttttt cttgatgatt ggtgcctact ctgacttcat tcagatagtc tctcactcta
    18961 gaaaccaatt tgtctggtgt acttgataga aaaacttcct gcccctgatt tccatggact
    19021 gtattgtcaa atgcaaagac agattttcca gcctgtacaa acttggagac aatagcatct
    19081 acttcttgaa agtgattgat atctagtaaa aagtcacagg tatcgactag aaagtttagc
    19141 tgttcttcat ttgtaatcgt tcggagacgg acattatagt tcgtttctaa gctacggatt
    19201 ttctcggaaa attgaacagg tgctgcaata tgaaaacaga tatttgacaa ggattcaagg
    19261 agataatcca actcttcaat ctgatcacta accgtcaaaa tcagagcatc tcctactaaa
    19321 tgatttttct tcatttgctt atttctctta atttctcaat cattgcttga acttggtcaa
    19381 cagcatatgc ctcctgacct acttcatagg ttttagtatt ttcaaaggat aagataggct
    19441 tgccaagatt agcaaattga tcgagaattt cttctgtctt ttcgccatga ttaatatcta
    19501 aaagtacttg actggtttct accaattcat tatcgacatc taccaaatag tgaattccgt
    19561 taaatatagt cacgtttgga taaattgtca tctgagccaa tcgatcacta actattactc
    19621 tagctgctat cttaaactga atatcaggca aggattgaac caatgtctca atttgttcaa
    19681 tatggtctga ggcagtatag attagacaag tgaaaggttc ctttattgga tagatgtgag
    19741 atctttgtaa tggatgtaaa tgatggtttt gtcccaattc tgtccattca agcccatgat
    19801 agtaccacca aacttcacga taagtttggg ccgccaaatc tttccacggt ttccgatgag
    19861 aaagatagtg aataatagca ggataatcct gaccctcagg caattgataa tcagcgaact
    19921 gtttatgaat gacaatatga ttataatcaa agtccaattc caaccattta tgttcaaaaa
    19981 gcatattcaa gatgctctga tctgcctgat ccaccttatt atgccattca ttagtcaaat
    20041 caattaattt ttgggtcata ttctcttttt tccaaaaagc attgtttacc aagagaacac
    20101 cggcattaaa gatttcttga ccaaaataag ctctgccccc aaaatctcta acagcagcca
    20161 aaggataacc ttgtaagtct gtagcaaaca agtcgtccat atttttcgtt acaactagat
    20221 cacagtccaa gtagagggcc ttgtcttctt gcacgaaatc agctatgaaa tagcgtaaaa
    20281 agactgtgta actaatatcc gatttataac atgaaatttg ctcagaagtt acccgacaat
    20341 taataatttc tgagtcaaac ttctctaagc gcttatttaa ttgcttaatc cattcatttg
    20401 gaaaatcgct atgaatcaga taaaaacgaa tcgaacgatt atgataacaa atagacttga
    20461 ttgtcgttaa aacttggtct acataggcat aatttgctgc taggacaatg gctttctttt
    20521 cactttcctc ttgtctcgat agctgattta aaagcctttg tttcatttca aactctttat
    20581 atgttgctgt gtcagataaa ccgctagctt gaccgttgga gagactgaat tccaacattt
    20641 gacgataaat cgccaaatgc ttttctaaag ggtaacccat attagctagt agcgtaatgc
    20701 gttcggacat ggcatcaacc aatgcatgca tccacttttc tgtccaaatt cttgatagac
    20761 taccttttct aataggataa gcataaagac ttttatttaa ataaattacc ttttctgata
    20821 ataaatatac cttttgattg aggtaaccat cttctcctaa tttacctatg tcaaagcgca
    20881 actgctcaaa caatctcgcc ttatagagtt taccccaagc agatatcaaa gcgaaactcc
    20941 tcatttcttg agtttcatac aaattctcaa agatggaaac attgtcatat accttctcat
    21001 aataggagtc tcctgatata tgaaagtaga acattccttc actttcgttg aaagaatagt
    21061 aattcccaac tgcaatatca gcttgatatt ctgttatttt tttatatagg gtttctacat
    21121 aatctaactc aatccaatca tctgaatcca caaaggtcac ataatttccg gacatattat
    21181 tcagaccggt gtttcgtgca gctgacagcc cagcattttc ttgttctata taggtaattc
    21241 ggtgatccat ttctgcaaat tctttacaaa tttcacctga agcatccgta gaaccatcat
    21301 taacgacaac aatctcaata tttttatatg tttgagtaat aatactatct aggcacttcc
    21361 tcagatagtt ttccacattg tatactggta caatgaccgt tattttatca tccactagca
    21421 attttctcct tgatttatgt gcgcgagtta gtttagccta actttacagg ttgtcttact
    21481 cttcttcatc acgtttacgg cgtttcgcaa ccaatccaat acctgtaaca gctgctagaa
    21541 ctccaagtaa cacagatcca attgacgact cagtacctgt attaggcaat tctttttggg
    21601 atttacctgt cgatccagaa gtatttccaa cttgtgagtt cgaatggttt gctgaatttg
    21661 aaactgatgt acttgctgaa gccgaagcac t
//
LOCUS       DAVLUM010000034        21117 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLUM010000034 DAVLUM010000000
VERSION     DAVLUM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.034"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            16..699
                     /locus_tag="VYN42_001157"
     CDS             16..699
                     /locus_tag="VYN42_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1462235.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            699..1433
                     /locus_tag="VYN42_001158"
     CDS             699..1433
                     /locus_tag="VYN42_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1462236.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            1587..2444
                     /locus_tag="VYN42_001159"
     CDS             1587..2444
                     /locus_tag="VYN42_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1462237.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            2586..3458
                     /locus_tag="VYN42_001160"
     CDS             2586..3458
                     /locus_tag="VYN42_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1462238.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFALQDKQLLKEQLEKAEVVLLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDTTASALTSFPKGTILVEKGPATRVWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            3740..4423
                     /gene="rpiA"
                     /locus_tag="VYN42_001161"
     CDS             3740..4423
                     /gene="rpiA"
                     /locus_tag="VYN42_001161"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1462239.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            4437..5648
                     /locus_tag="VYN42_001162"
     CDS             4437..5648
                     /locus_tag="VYN42_001162"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1462240.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            5650..6210
                     /locus_tag="VYN42_001163"
     CDS             5650..6210
                     /locus_tag="VYN42_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1462241.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKNNKGDTQ"
     gene            6207..7016
                     /locus_tag="VYN42_001164"
     CDS             6207..7016
                     /locus_tag="VYN42_001164"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1462242.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            7492..8472
                     /locus_tag="VYN42_001165"
                     /pseudo
     CDS             7492..8472
                     /locus_tag="VYN42_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            8497..9009
                     /locus_tag="VYN42_001166"
     CDS             8497..9009
                     /locus_tag="VYN42_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1462243.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTADFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            9667..10377
                     /gene="deoD"
                     /locus_tag="VYN42_001167"
     CDS             9667..10377
                     /gene="deoD"
                     /locus_tag="VYN42_001167"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1462244.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(10400..10924)
                     /locus_tag="VYN42_001168"
     CDS             complement(10400..10924)
                     /locus_tag="VYN42_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1462245.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAVDCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(10977..11213)
                     /locus_tag="VYN42_001169"
     CDS             complement(10977..11213)
                     /locus_tag="VYN42_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1462246.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLVK"
     gene            complement(11281..12201)
                     /locus_tag="VYN42_001170"
     CDS             complement(11281..12201)
                     /locus_tag="VYN42_001170"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1462247.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            12391..12794
                     /locus_tag="VYN42_001171"
                     /pseudo
     CDS             12391..12794
                     /locus_tag="VYN42_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13010..13591
                     /locus_tag="VYN42_001172"
     CDS             13010..13591
                     /locus_tag="VYN42_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1462248.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            13588..14865
                     /locus_tag="VYN42_001173"
     CDS             13588..14865
                     /locus_tag="VYN42_001173"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1462249.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDMIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            14883..15545
                     /gene="deoC"
                     /locus_tag="VYN42_001174"
     CDS             14883..15545
                     /gene="deoC"
                     /locus_tag="VYN42_001174"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1462250.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLSQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            15532..15921
                     /locus_tag="VYN42_001175"
     CDS             15532..15921
                     /locus_tag="VYN42_001175"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1462251.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            16011..17063
                     /locus_tag="VYN42_001176"
     CDS             16011..17063
                     /locus_tag="VYN42_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1462252.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            17207..18742
                     /locus_tag="VYN42_001177"
     CDS             17207..18742
                     /locus_tag="VYN42_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462253.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDSLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTDKQELGVLMAGGNLGKEK
                     SDV"
     gene            18735..19793
                     /locus_tag="VYN42_001178"
     CDS             18735..19793
                     /locus_tag="VYN42_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1462254.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            19796..20752
                     /locus_tag="VYN42_001179"
     CDS             19796..20752
                     /locus_tag="VYN42_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1462255.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            20837..21117
                     /locus_tag="VYN42_001180"
                     /pseudo
     CDS             20837..21117
                     /locus_tag="VYN42_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6209 a         3747 c         4866 g         6295 t
ORIGIN      
        1 gaaagcagtg tgactatgaa tttttctttt ttacctaagt atttacctta ttttaactat
       61 ggggctgttg tgacgattct tatttctatc tgtgttatct ttttgggaac tattttgggt
      121 gttgtcttgg cttttgggca acgttcaaag tttaaaccgc ttgtttggtt ggccaacttg
      181 tacgtttgga ttttccgtgg gacaccgatg atggttcaaa ttatgattgc ctttgctctt
      241 atgcatatca atgctccgac tattcagatt ggaattttag gtgttgattt ttcgcgtctg
      301 attccaggga ttttgattat ctctatgaat agtggtgctt atgtttcgga gactgttcgt
      361 gccggaatca atgcggttcc aaaaggtcag ctagaagcgg cttattcgct agggattcgt
      421 cctaaaaatg cgatgcgtta tgtgattttg ccacaagcag tcaaaaatat cttgccagca
      481 ttggggaacg aatttatcac cattatcaag gacagctccc tcttatcagc tattggggtc
      541 atggagttgt ggaatggggc tacaacagtt tctacaacaa cctatctacc tttaacacca
      601 cttttatttg cagcatttta ctacttgatt atgacctcta ttctgacagt agccttgaaa
      661 gcttttgaaa aacatatggg acaaggagat aagaaataat gacagaaacc ttgataaaaa
      721 ttgaaaattt acataaatct tttggaaaga atgaagtatt gaagggcatc aacctcgaga
      781 ttaaaagagg agaagttgtc gttatcatcg gtccttcagg gagtgggaaa tctaccttgc
      841 ttcgctctat gaatttgttg gaggaagcaa ccaaggggaa gcttatcttt gagggagtcg
      901 atattacgga caagaagaat gacctgtttg ccatgcgtga gaagatgggc atggttttcc
      961 aacaatttaa cctctttcct aatatgactg tgatggaaaa tattaccttg tcacctatca
     1021 agactaaagg tgaaagcagg gaagttgctg agaagagagc ccaagagctt ttggaaaaag
     1081 ttggtttgcc agataaggca gacgcttatc cacagagtct gtcgggtggg caacaacaac
     1141 ggattgccat cgcgcgtggg ttggctatgg aaccagatgt tttgctcttt gacgaaccaa
     1201 cttcagcctt ggatcctgaa atggtaggtg aggtattggc tgttatgcaa gaccttgcca
     1261 agtcaggaat gactatggtt atcgtaacac atgagatggg atttgcccgt gaggtggcag
     1321 atcgtgttat ctttatggca gacggtgtgg ttgttgaaga tgggacacct gagcagattt
     1381 ttgaacaaac ccaagaacaa cggactaaag atttcttgag taaggtttta taatctattt
     1441 taaaatttca agacaagatt agtgaaaagt tcaaccagag ctttttctta tagtttgaaa
     1501 ctataggata acctaggaaa gaagtgttag agggcactag cagtttttgg tataatggaa
     1561 gatatttgaa agaaaagaga agtgatatga cacagattat tgatgggaaa gctttagcgg
     1621 ccaaattgca ggggcagttg gctgaaaaga ctgcaaaatt aaaggaagaa acagctctag
     1681 tgcctggttt ggtagtgatt ttggttgggg ataatccagc cagccaagtc tacgttcgca
     1741 acaaggagag gtcagctctt gcggctggtt cccgtagcga agtagtgcga gttccagaga
     1801 ctattactca agaggaattg ttagacctga ttgctaaata taatcaggat ccagcttggc
     1861 atgggatttt ggtccagttg ccattaccaa aacatatcga tgaagaggcg gttttattag
     1921 ccattgaccc agaaaaggat gtggatggtt tccatcccct aaacatggga cgtctttggt
     1981 ctggacatcc agtcatgatt ccctcgacac ctgcaggaat tatggaaatg tttcatgaat
     2041 atgggattga cttggaaggt aaaaatgcgg tcgtaatcgg tcgttcaaat atcgttggaa
     2101 aacctatggc tcagcttctt ttggctaaaa atgcgacagt aaccttggcc cactcacgaa
     2161 ctcataatct tgccaaggtg gctgctaaag cagatattct tgtagtcgca atcggccgcg
     2221 ccaagtttgt gactgctgac tttgtcaaac caggtgcggt tgtcattgac gttgggatga
     2281 atcgagatga aaatgggaag ctctgtggag atgttgatta tgaggcagtt gcaccacttg
     2341 ctagccatat cacgccagtc cctggaggtg tcggtcctat gaccattacc atgctgatgg
     2401 agcaaactta tcaagcagca cttcggacat tggatagaaa ataagagaag cattcgatta
     2461 atagagtgta ttttctatag ctatatctaa aatggcagaa atgaatatta aattttagat
     2521 ataagattac aaaaggaggt ctgcgtctcc tttttattgt ataataaaag tgagaggaaa
     2581 aaaggatgaa agtgattaat caaaccttat tagaaaaagt tattattgaa cgttctcgtt
     2641 caagtcataa aggagattat ggtcgtctgc tgctgcttgg tggtacttat ccttatggag
     2701 gtgccatcat catggctgct ttagcagctg taaaaagcgg tgcaggattg gtgaccgttg
     2761 gaacggacag ggaaaatatc cctgctctgc acagtcattt acctgaggct atggcctttg
     2821 ctcttcaaga caagcaattg ttaaaagagc agttggagaa ggcagaagtt gttttgctgg
     2881 gacctggttt aggagacaat gcttttggag aagatttagt taaacaggtc tttgctggct
     2941 taaaacagaa tcagattttg attgtagacg gaggtgcttt gactattctt gctaggacaa
     3001 gtctgtcatt tccttctagc cagcttatcc taactcccca ccaaaaggag tgggaaaaac
     3061 tgtctggaat tacgattgaa aagcaaaagg aagatacaac ggctagtgcc ctgacttctt
     3121 tccctaaagg aacaattttg gtggagaaag gtccggctac tcgtgtttgg caagctggcc
     3181 agtctgatta ttaccagtta caggttggcg gtccctatca ggcaactggg ggaatgggag
     3241 atactctggc tgggatgatc gcaggatttg taggccaatt ccgacaggcc agtctctacg
     3301 agcgtgtagc agtagcgacc catcttcatt cagccatagc ccaagaacta tctcaagaaa
     3361 attatgtggt cttaccgacg gaaatcagca ggtatcttcc caaaataatg aaaattattt
     3421 gtcaacaaga gagggtaagc aaagataaac ttgtttaaaa tagacagata aatctacttc
     3481 cttctcttaa tttatgattc ttgaaatgcg cctgctttaa ggctaaacta gacgtatcaa
     3541 agttaagagt ttgtttttgt aactggaaag agatgaacaa atcaaataca taaaagataa
     3601 actcattttt attcgtttgg taaaaataaa atgcatattt ttaaagaaag attgatgaaa
     3661 aatgtagatt tgatgttttt acttgaataa aaagcggttt catagtaaaa taagaactga
     3721 gaatgatgga ggtaaatcgg tggaaaatct gaagaaaatg gcaggtatca aggctgctga
     3781 gttcgtgagc gatggaatgg tcgttggact tggaacaggc tcgactgcct attattttgt
     3841 cgaagaaatc ggtcgtcgta tcaaggaaga aggattacag attacagctg taacaacttc
     3901 tagtgtgacc actaaacagg cagaaggcct taatatcccg ctcaagtcta ttgaccaagt
     3961 agactttgtc gatgtgacgg ttgatggcgc ggatgaagtg gatagtcagt ttaatggaat
     4021 caaaggcggt ggtggtgccc ttctcatgga aaaggtggtc gcaacaccat caaaagaata
     4081 catttgggtg gtggatgaaa gcaagctggt cgaaaaacta ggtgctttta aattgccagt
     4141 agaagtggtt cagtatggtg cagagcaggt ctttcgtcat tttgaacgag ctggctacaa
     4201 accaagtttc cgtgaaaaag acggccaacg ttttgtgacg gatatgcaga attttatcat
     4261 tgacctcgcc ttggatgtca ttgaaaatcc aattgctttt ggacaagaat tggaccatgt
     4321 cgttggtgtt gtggagcatg gtttattcaa ccaaatggtg gataaggtaa tcgttgctgg
     4381 acgagatgga gttcagattt caacttcaaa aaaaggaaaa tagaaggggg cataagatgt
     4441 ctaaatttaa tcgtattcat ttggtggtac tggattctgt aggaatcggt gcagcaccag
     4501 atgctaataa ctttgtcaat gcaggggttc cagatggagc ttctgacaca ctgggacaca
     4561 tttcaaaaac agttggtttg aatgtcccaa acatggctaa aataggtctt ggaaatattc
     4621 ctcgtgaaac tcctcttaag accgtagcag ctgaaatcaa tccaactgga tatgcaacaa
     4681 aattagagga agtatctctt ggtaaggata ctatgactgg acactgggaa atcatgggac
     4741 tcaacattac tgagcctttc gatactttct ggaacggatt cccagaagaa atcctgacaa
     4801 aaatcgaaga attctcagga cgcaaggtta ttcgtgaagc caacaaacct tattcaggaa
     4861 cggctgttat cgatgatttt ggaccacgtc agatggaaac tggagagttg attatctata
     4921 cttcagctga ccctgttttg cagattgctg cccacgaaga cattattcct ttggatgaat
     4981 tgtaccgtat ctgtgaatac gctcgttcga ttacccttga gcgtcctgcc cttcttggtc
     5041 gcatcattgc tcgcccttat gtaggtgaac caggtaactt cactcgtacg gcaaaccgtc
     5101 gtgacttggc tgtatctcca ttttccccaa ctgttttgga taaattgaat gaggctggta
     5161 tcgatactta tgctgtgggt aaaatcaacg atatctttaa cggtgctggt atcaaccatg
     5221 acatgggtca caacaagtca aatagtcatg gaattgatac actattgaag actatgggac
     5281 ttgctgagtt tgaaaaagga ttctcattta caaacctagt tgactttgat gccctttacg
     5341 gccatcgtcg taatgctcac ggttaccgtg attgcttgca tgagtttgat gaacgcttac
     5401 ctgaaattat cgcagctatg agagagaatg accttctctt gattactgcg gaccatggaa
     5461 atgacccaac gtatgcagga acggatcaca ctcgggaata tattccattg ttggcctata
     5521 gccctgcctt taaaggaaat ggtctcattc cagtaggaca ttttgcagat atttcagcga
     5581 ctgttgccga taactttggt gtggaaactg ctatgattgg ggaaagtttc ttagataaat
     5641 tggtataaga tgacgcgcta tgctttgctg gtgagaggta tcaatgttgg tggtaagaat
     5701 aaggtcgtca tggcggagct tcgtcaagaa ttgacaaact tgggactgga aaaggttgag
     5761 agctacatca atagtggcaa tattttcttt acttcgatag attccaaagc ccaattggtt
     5821 gaaaagctag agactttctt tgcagtccat tatccattta ttcagagctt ttctttactg
     5881 agtctagagg actttgaggc ggaacttgaa aatctaccag cttggtggag cagagacttg
     5941 gcacgaaaag attttctctt ttacactgag ggtttggatg tggaccaagt catcgcgaca
     6001 gttgaaagtt tagagctgaa agatgaagtg ctttattttg gaaaacttgg gattttctgg
     6061 gggaaatttt ctgaagaatc ctattctaag actgcctatc ataagtactt gctgaaggtg
     6121 cctttctacc gccacattac tattcgtaat gctaaaacct ttgacaaaat tggtcaaatg
     6181 ctaaaaaata ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta
     6241 ctttcctgaa agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac
     6301 ttggagaatt ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa
     6361 actggggccg ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag
     6421 gtcgcaaggt cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag
     6481 tggtgacttt cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca
     6541 atgcagctgg cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca
     6601 acatgacggg gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc
     6661 cagatatgtc tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa
     6721 aacttaatat caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa
     6781 caccagcaga aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg
     6841 ttcctgaagt tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca
     6901 ctaactttgc ggccggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg
     6961 aacgtgttaa aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa
     7021 aaagatttaa aagggggagt gcctctgttt tttcaggatt gactgcctat ccggattaaa
     7081 gaagaaacag aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga
     7141 ataggtatgt ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat
     7201 tagcttccta gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg
     7261 aatttctcag tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata
     7321 aacgaaaaga aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa
     7381 aaaattaagt atcggagttg tatctgttgt agttggcttt gatttctagc tccagctgga
     7441 atttcagcca atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat
     7501 tctaaggagg aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga
     7561 gaggagccaa gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa
     7621 agggaagagt caaaagtaga gataacataa ccagctcaag cggatgatat ccgcaaggtt
     7681 gttggggaat tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt
     7741 ggatgttacc tagctcagat tgcagcggtt gaagcttacc aaaaatatcc tgatttttat
     7801 aaccatgtat tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact
     7861 gtttggaatg ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt
     7921 agtggaaaaa ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat
     7981 aataatcgtg atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc
     8041 tattttgaaa gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg
     8101 gataaacatg gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct
     8161 ctgcctcgat cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa
     8221 caggttactc aaagttcgac agttttcgga ggagatgcta gaagagctgt ggatggcaaa
     8281 gtcgatggta actatggtca caattctgtc actcatacaa acttccaatc taagccttgg
     8341 tggcaagtag atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca
     8401 gacactgccc aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa
     8461 gaaattgagt aaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac
     8521 cataaaaaag tgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca
     8581 gaagttgaag ttttccgctt tatagctacg aatgctgaaa cggcgacaca agtttctaag
     8641 ccagttcaac caatcagtca gactcctgtg aaagataaaa cattgacaat tcaacacagt
     8701 ggagcttaca ttgcccgcta ctccataact tgggaagaag ttccagtaga taaagatgga
     8761 aaccaagttg ttcgtagtca ttcttgggaa ggaaacggtt gcaaccagac tgcagatttt
     8821 gtcctcaacc tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag
     8881 acgggcctac tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa
     8941 ccccaccgta aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat
     9001 gtcttgtaat ctgatggtac aatgacagtt agtttgtcta gtttataaga aagtactacc
     9061 tgagcttgaa tagaactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa
     9121 atcaaagagc aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta
     9181 gataagactg acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag
     9241 agattttcga agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag
     9301 aaaacttttc taaaaacaaa aacgaaagga tgggtaaact gtattcgctg aactgaatac
     9361 gggcgactct cctctaaatc aaaattaaga aagaaaggaa ttgaacccac cctaaaagca
     9421 gtgggaaaaa gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc
     9481 ttcgcttttt gacgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag
     9541 agcgtgtgtt ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa
     9601 aatcaggatt tctcgtcggc ttcctaattt tcagtcgttt tcttctcgct ctttgtatca
     9661 taaattatgt ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt
     9721 cctggggatc ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt
     9781 tttaacgaag tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct
     9841 gtcatgggaa ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta
     9901 gactacggtg tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt
     9961 catgttcgtg aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat
    10021 gactggccac agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac
    10081 catatcgcca aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc
    10141 ttttactcaa attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg
    10201 gaaatggaag cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct
    10261 atcatgacca tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt
    10321 caaaatacct tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta
    10381 tagccaaaaa ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat
    10441 ctagctctct ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt
    10501 ggtaattttc tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc
    10561 actcaaagcg ttcagggcaa tctaccgcca tactttctct gacttttcca cggtatttaa
    10621 gataacgctt aaaggctcta aagagacagg tcaatggcga aaaattgaga aagatgattt
    10681 ggtcagcttc ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc
    10741 aagctttatg cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt
    10801 cttgccaacc aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt
    10861 tagataactt ttctgctata gttgacttac cagaaccaga atatccgata attgcgattt
    10921 tcattttcta ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat
    10981 ttaacaagtt tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa
    11041 cctttagttt ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg
    11101 tttgcttcga aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg
    11161 ttttgtttaa cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt
    11221 acctccatat ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa
    11281 ttactttttt aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc
    11341 tgcacgattt ctggttggtt caatataatt ttgcagattt gtgagattga tactgatcca
    11401 gacctgatgg gcaaaggact ccacttcccc aatcggcatc tgagtaaaac gataatagta
    11461 gctatcaggg tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact
    11521 ttcaatatca tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata
    11581 gagacgatcg ttttgtggat tttgaaagac attaattccc tcaacaatta caaaatcagc
    11641 agctttgaca ctttgtttct tttcgggtac gatgtcgtaa acttcatgag aatagacagg
    11701 aatatctaca tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc
    11761 atagctttca ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg
    11821 atagagaaaa ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag
    11881 taggatttga agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc
    11941 aataataaaa ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa
    12001 atcttcctta gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt
    12061 aacgtcttgg agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt
    12121 caaaggaggt gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa
    12181 atgtaaaaat tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa
    12241 agctaaaaaa ataaagcggt ttcttgaatg ttgtaagtca atgatatata atataagtga
    12301 tcaatttatt gatgaaatag gagatagatt ctactgattt ataagcttat aaagggggct
    12361 ttttagttca caacttatag gaggtgtact atgaaaatct taaaacgtta catattggaa
    12421 ctctgtttta ttttaagttt tgctttacct tttataaaag gaaccaatgc agataatggt
    12481 agatgctttg tggaaaccta ttacggtttt acttttttga tggaacatgc tattgtaaca
    12541 gctgtcttta tttgttcgtt cttaattgct ttcttactaa aaaacgatgg acgaaatgga
    12601 ttgctgcggg tagttattgc tttttagtcc tacggattgc gacagagggt tatttcttcc
    12661 acatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg acacaaacgt
    12721 atcagttggg cttttatcta aacattttgt taggaatttt gttgataata aagtatttta
    12781 aggttaagca atagaaataa taatctgcct gattatagat gataaacttt ttgtttttat
    12841 ctggactgtg atatttatag ttctaaatga tttattattt ataagtgttg aaagagattg
    12901 aagaaaatgg cttcgtgact tgctttcttc ggtctttttc gttttattat caatttgtaa
    12961 acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa tgtactatgc
    13021 agaaaatcct gacgctgctc acgacattca tgagttgaga gtggacttgt tgggagaaaa
    13081 aatgactttt ttgacagatg cgggtgtttt tagcaagaaa atggttgact ttggaagtca
    13141 actcttgctc aagtgtctgg atgtcaacca aggagagaca gtcctagatg taggctgtgg
    13201 ttatggtcca ttaggtttgt ccttggtcaa ggtttacgga gttcaggcga ccatggttga
    13261 tattaacact cgtgccctgg atttagctca gagaaatgct gaaaaaaata atgcaaaagc
    13321 gacgatattt caatctaata tttatgcaag agttcaaggg cgatttgacc atgtcatttc
    13381 caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcatcgaga aaagtaaaga
    13441 tttcttggaa attggtggcg atttgaccat cgtcatccag aaaaaacaag gagctccaag
    13501 tgccaagtct aagatggaag atgtgtttgg caattgtgaa atccttaaaa aagacaaggg
    13561 atactatatc cttagaagtg tgaaagaatg agagcagttg atttaatcca aaaaaaacga
    13621 gacggtcaag aactgacttc aagtgaaatt gaatggctga tagaaggcta tgtatcagga
    13681 actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa aggaatgacg
    13741 actcgagaaa tctctgattt aacgatgaat atggttaaga ctgggcaaga gtttgacctg
    13801 tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg cgataaggta
    13861 accttgattt tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa aatgagtggt
    13921 cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattaa gggctatcaa
    13981 gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt atctgtcatt
    14041 gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg tgatgtgacc
    14101 gcaactgtcg acatgattcc tttgattgcg agttcggtga tgagcaagaa aattgcggca
    14161 ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat gaagacggtt
    14221 gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt tggacggaag
    14281 acagtagcag tgattacgga tatgagccag cctttgggac gagcgattgg aaatcgtctg
    14341 gaaatccttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat tacccacttt
    14401 atttgtgaat tggctcaaat tatgcttggt ttggcaaatg ttaacaaaac tgttgaagaa
    14461 gttcgccaac atcttgaaaa tggtcaagca ctggctaagt ttgaggaaat ggtgcaagcc
    14521 caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt ggtggaaatc
    14581 cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg tctttatgcc
    14641 atgaggctgg gtgctggtcg tgcagttaag tctgatgtct tggactatga aacaggaatt
    14701 gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc aaaagtatac
    14761 acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt taaaataagt
    14821 gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga gggaaaaccg
    14881 aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca aagaaaaaac
    14941 aaattgatag tttgttgtct gaggctagag agtatgactt tgccagtgtt tgcgttaatc
    15001 cgacctgggt tgaacatgct aaaaaaggac ttgaaggcac agatgttaag gtttgcacag
    15061 tagtaggttt ccctttggga gcaacaactt cagccgtgaa agcatttgag acaaaagaag
    15121 ctatccaaaa tggtgcagat gagattgata tggtgatcaa tgttggggct ctcaagtcag
    15181 gtgatttggc cttggttgag tcagatattc gcgcagtagt ggaagcaagt ggtgataagt
    15241 tagtgaaagt cattattgaa gcttgccttc tgacagacca agaaaaagtt gttgtttgcc
    15301 aattgtccca aaaagctggg gctgactttg tcaaaacatc tactggcttt tcaactggtg
    15361 gtgctacgat agcagatgtt acattaatgc gtgaaacagt tggatctgat atgggtgtca
    15421 aggccgccgg tggagctcgt tcttatgcag atgctcttgc ctttgtcgaa gcaggtgcga
    15481 cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca gatggcgact
    15541 actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc ctattctcac
    15601 tttcctatcg gagcagtttt agtagctaaa gacggaagtg tttacacggg agtgaatatc
    15661 gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagcagtttt taaggctata
    15721 tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga aaaaccgatc
    15781 tcgccatgtg gtgcttgtcg ccaagtgatg gctgaatttt ttgaacaaga tctaaaagtg
    15841 accttagtcg caaaagataa atcgacggtc gagatgacgg tcggggaatt acttccatac
    15901 tcttttacag acttaaacta gtctgagtcg ctctctgagt ggcacggtcc ttgtggccaa
    15961 ccaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    16021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    16081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    16141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    16201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    16261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatcttcg
    16321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    16381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    16441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    16501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    16561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    16621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    16681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    16741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    16801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    16861 tgaaacaagt tggtacaact gtaaaagata ttgctaacaa ggcagaaaaa ggagaattcc
    16921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    16981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    17041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    17101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    17161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    17221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    17281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    17341 gtccacgcta atgaacatgt tagcaggcct tcttgaacca actagtggtg aaattgcggt
    17401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    17461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    17521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    17581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    17641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    17701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    17761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    17821 tcgagcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    17881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtaggacgtt ctgtttcctt
    17941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    18001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    18061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    18121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    18181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    18241 tgatagcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    18301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    18361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    18421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    18481 tatcgttagt cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    18541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    18601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    18661 atcaccagaa acaaccgata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    18721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    18781 tcctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    18841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    18901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc cgttgccagt cgagctggtt
    18961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    19021 ccctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    19081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    19141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    19201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    19261 atgcaaccta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    19321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    19381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    19441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    19501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    19561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    19621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    19681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    19741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    19801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    19861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    19921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    19981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    20041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    20101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    20161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    20221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    20281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    20341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    20401 atatttaggg gttattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    20461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    20521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    20581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    20641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    20701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    20761 aaaaacgtca gtccaatgac tgaactacac cccaaaagtt agacagaaaa aatctaactt
    20821 ttggggtgtt tttattatga aattaagtta tgatgataaa gttcagatct atgaacttag
    20881 aaaacaagga tatagcttag agaagctttc aaataaattt gggataaaca attctaatct
    20941 taggtatatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa aaggaaaaaa
    21001 tcgttactat tctcctgatt taaaacaaga aatgattcat aaagtctgac atgaaggctg
    21061 gactaaagat agagtttctc ttgaatacgg tctcccaagt cgtacgatac ttcttaa
//
LOCUS       DAVLUM010000035        21070 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLUM010000035 DAVLUM010000000
VERSION     DAVLUM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.035"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            281..520
                     /locus_tag="VYN42_001181"
                     /pseudo
     CDS             281..520
                     /locus_tag="VYN42_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            664..1893
                     /locus_tag="VYN42_001182"
     CDS             664..1893
                     /locus_tag="VYN42_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1462256.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            1913..4609
                     /gene="ppc"
                     /locus_tag="VYN42_001183"
     CDS             1913..4609
                     /gene="ppc"
                     /locus_tag="VYN42_001183"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1462257.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    4692..4909
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5022..6026
                     /locus_tag="VYN42_001184"
     CDS             5022..6026
                     /locus_tag="VYN42_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1462258.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6095..6961
                     /locus_tag="VYN42_001185"
     CDS             6095..6961
                     /locus_tag="VYN42_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1462259.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLLTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            6958..7716
                     /locus_tag="VYN42_001186"
     CDS             6958..7716
                     /locus_tag="VYN42_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462260.1"
                     /translation="MTAIVELKNATKVVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLTSYKNEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            7806..9566
                     /gene="dnaG"
                     /locus_tag="VYN42_001187"
     CDS             7806..9566
                     /gene="dnaG"
                     /locus_tag="VYN42_001187"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1462261.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVAEDKQFYHCFGCGRSGDVFKFIEEYQGVPFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFRIGLAPPE
                     RNYLYQRLSGQYRDEDFLDSGLFYLSDANQFVDTFYNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRSGI
                     ENAVASMGTALSREHVEYLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSITAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            9569..10678
                     /gene="rpoD"
                     /locus_tag="VYN42_001188"
     CDS             9569..10678
                     /gene="rpoD"
                     /locus_tag="VYN42_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1462262.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGIATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            10692..11021
                     /locus_tag="VYN42_001189"
     CDS             10692..11021
                     /locus_tag="VYN42_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1462263.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11136..12179
                     /gene="cpoA"
                     /locus_tag="VYN42_001190"
     CDS             11136..12179
                     /gene="cpoA"
                     /locus_tag="VYN42_001190"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1462264.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVE
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12195..13520
                     /locus_tag="VYN42_001191"
     CDS             12195..13520
                     /locus_tag="VYN42_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1462265.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            13551..13727
                     /locus_tag="VYN42_001192"
     CDS             13551..13727
                     /locus_tag="VYN42_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1462266.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            13786..13920
                     /locus_tag="VYN42_001193"
     CDS             13786..13920
                     /locus_tag="VYN42_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1462267.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            13984..15294
                     /gene="obgE"
                     /locus_tag="VYN42_001194"
     CDS             13984..15294
                     /gene="obgE"
                     /locus_tag="VYN42_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1462268.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIVPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15304..15462
                     /locus_tag="VYN42_001195"
     CDS             15304..15462
                     /locus_tag="VYN42_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462269.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            16511..17770
                     /locus_tag="VYN42_001196"
     CDS             16511..17770
                     /locus_tag="VYN42_001196"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1462270.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            17786..18337
                     /locus_tag="VYN42_001197"
     CDS             17786..18337
                     /locus_tag="VYN42_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462271.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18330..19607
                     /locus_tag="VYN42_001198"
     CDS             18330..19607
                     /locus_tag="VYN42_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1462272.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            19623..20483
                     /locus_tag="VYN42_001199"
     CDS             19623..20483
                     /locus_tag="VYN42_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1462273.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            20708..20818
                     /locus_tag="VYN42_001200"
                     /pseudo
     CDS             20708..20818
                     /locus_tag="VYN42_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            20864..>21070
                     /locus_tag="VYN42_001201"
     CDS             20864..>21070
                     /locus_tag="VYN42_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEV1462274.1"
                     /translation="MNYEASKQLTDARFKCLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYE"
BASE COUNT         6446 a         3612 c         4756 g         6256 t
ORIGIN      
        1 atgcaaaatc ttacaaatct aaaagaaaga atgctaaaat agaaaatgat aaattgtgtt
       61 ttaataccgt aaccgatgac gaaaaaaagt gtacaaataa agaaaacagc gcacgtggag
      121 tgtgtaagct tgttgctaaa agcgtaaaaa ccttggaacg aaaggaataa tagacttcct
      181 gcgaaacaaa aatacaatac aataaaacta tggatgatga agcaagtaaa caattaagcg
      241 atagccgttt caagagcctt gtaggtgttc agcgcacgag atgttagctg tgttaaaaac
      301 agcttatcaa cgcaacgtaa acgcgcaaaa ggtggacgaa aaaccaaatt aagcctagac
      361 gatctcctca tggtaactat tcaatacatg cgagaatagc gcacttatga acaaattgcg
      421 gctgattttg gcattcacga aagcaacata attagtcgga ggtcaatgga ttgaagcaac
      481 tcttattcaa aatggtttta cgatttcaaa ttctgcctta attctgtaaa aacagtaaaa
      541 ttcgaaggat tgtaaggtaa gagttttttt ctttctgaaa aaatggtata atagcaatca
      601 aaactagaaa ataaaacgga atttggaaca gatttgtctg tatcctagta gagtggtgat
      661 actatgaaga ttagtaagag gcacttatta aattattcca tcttgattcc ctacttgctt
      721 ttatctattt tgggcttgat tgtggtctat tcgaccacca gtgctatttt aattgaagaa
      781 ggcaagagcg ccttgcagtt ggttcgaaac caaggaatct tttggattgt tagtttgata
      841 ctgattgcct taatttataa attgagacta gattttttga gaaatgagcg actaatcatt
      901 ttagttatat taatagaaat gcttttattg ttcttggctc gttttattgg tatttcagta
      961 aacggggcat acggttggat ttcggttgca ggagtaacta ttcagccagc tgagtactta
     1021 aaaatcatta ttatttggta tttagctcac cgattctcca aacagcaaga agaaatagct
     1081 acttatgatt ttcaagtttt gactcaaaat caatggcttc cccgtgcttt taatgattgg
     1141 cgattcgttc tcctagttct gattggaagt ttgggaattt tccctgattt aggaaatgcg
     1201 actattttag tcttggtttc cttgattatg tatacagtta gtggaatcgc ttatcgctgg
     1261 ttttcaacca ttctggcgct cgtatctgcc gcttctgtct ttgtcttgac cactatcagc
     1321 ctaatcggtg ttgagacctt ttcaaaaatt ccagtatttg gctatgtagc caaacgcttt
     1381 agtgcctttt ttaatccttt tgccgatcgt gctgatgcag gtcaccagtt agctaattct
     1441 tattttgcca tggtcaatgg tggttggttt ggtctaggtc ttggaaactc gattgaaaaa
     1501 cgaggttatt tgccagaagc tcatacagac tttgtctttt ctatcgtgat tgaagaattt
     1561 ggctttgttg gtgccagtct tattttagct ctcttgtttt tcatgatttt gcggattatc
     1621 ttggtcggta ttcgagcgga gaatcctttc aatgccatgg ttgcactcgg tgtcggaggg
     1681 atgatgttgg ttcaggtatt tgtcaatatc ggagggattt cgggcttgat tccatctaca
     1741 ggagtaacct tccccttctt atcccagggt ggaaatagtc ttctagtctt atcagtggca
     1801 gtagcctttg tcttaaatat tgatgccagt gaaaaacgcg ctaagttgta ccgagaattg
     1861 gaaaatcaac caatgaacct tctgttgaag taggataaag aaaggatagt ttatgtctct
     1921 tcaaaaatta gaaaattcta gtaataaaag tgttgtgcaa gaagaagtct tgattctaac
     1981 agaattactg gaagatatta ctaaaaatat gcttgcccca gagacctttg aaaaaataat
     2041 acagttgaaa gaattatcaa cgcaggaaga ttatcaaggt ctaaaccgtc tagtgactag
     2101 cttatcaaat gatgaaatgg tctatatttc acgctatttc tctatcttgc ctcttttgat
     2161 taatatttca gaggatgtgg atttagctta tgaaatcaat catcaaaata atattgatca
     2221 ggactattta ggtaaattat ctacaacgat taaattggta gcagaaaagg aaaatgccgt
     2281 tgagatccta gaacacttga atgttgttcc agttttgaca gcccatccaa cacaagtgca
     2341 acgcaaaagt atgttggatt taacaaatca tattcatagt cttttgcgta aataccgtga
     2401 tgttaagttg gggttgatca ataaagataa atggtacaat gatttgcgtc gttacatcga
     2461 aattatcatg cagacagaca tgattcgtga gaaaaaatta aaagtgacta acgaaatcac
     2521 gaatgctatg gaatattata acagctcctt tttgaaagct gtacctcatt tgacgacgga
     2581 gtataagcgc ttagcgcaag cgcatggtct gaatttaaaa caggctaaac caatcaccat
     2641 gggtatgtgg ataggtggtg accgtgatgg aaatccattt gttacagcaa agaccttgaa
     2701 gcagtctgca ctcactcagt gtgaagtcat catgaactac tatgataaaa agatttacca
     2761 actttatcgt gaattttctc tttcaactag cattgtcaac gtcagcaagc aagtcagaga
     2821 aatggctcgt caatccaagg ataactcgat ttaccgcgaa aaagagcttt accgtcgtgc
     2881 cttgtttgat attcaatcaa aaattcaggc aactaaaacc tatctgattg aggatgaaga
     2941 agttgggact cgttatgaaa ccgccaatga tttctacaag gatttgattg ccattcgaga
     3001 ttctctacta gaaaataagg gcgagtcctt gatttcaggt gattttgtgg aattattgca
     3061 ggcagtagag atatttggtt tttacttagc atcaattgat atgcgacaag actctagcgt
     3121 ctatgaagcc tgtgtggcag aactcttgaa atcagcagga attcattctc gttatagcga
     3181 gttgagcgaa gaagaaaagt gtgaccttct cttgaaagaa ttagaagaag atccccgaat
     3241 tctttctgcg actcacgcag aaaaatcaga attattagca aaagaactag ctatttttaa
     3301 gacggctcgt gttttgaaag ataagttggg agatgatgtc atccgtcaga ccatcatttc
     3361 acatgcaacc agcctttctg atatgctaga attagctatt ctgttaaaag aagtaggact
     3421 ggtggatacg gaaagggcgc gtgttcagat tgttcccctt tttgaaacaa ttgaagactt
     3481 ggatcattca gaggaaacaa tgagaaaata tctttctctt agccttgcca aaaaatggat
     3541 tgactcacga aataactacc aagaaatcat gcttggctac tctgacagta ataaagatgg
     3601 cggttacttg tcatcatgtt ggaccctcta caaggctcaa caacaattga ctgctattgg
     3661 agatgaattt ggcgttaagg ttaccttctt ccatggtcgt ggtggtactg tcggtcgtgg
     3721 tggtgggcca acctatgaag ccattacatc tcaaccgctc aagtctatca aggatcgtat
     3781 ccgcttgacg gagcagggtg aagtaattgg gaataaatac ggtaacaaag acgccgctta
     3841 ctataacctt gaaatgctag tatcggcagc tattaaccgt atgattactc agaagaagag
     3901 cgataccaat accccaaatc gttatgaagc cattatggat caagtagtgg accgtagtta
     3961 cgatatctac cgtgatttgg tctttggtaa tgagcatttc tatgattatt tcttcgagtc
     4021 aagtccaatc aaggctattt caagttttaa tattggttct cgtccagccg ctcgtaagac
     4081 tattactgaa atcggtggat tgcgtgctat cccttgggta ttctcatggt cacagagtcg
     4141 tgttatgttc cctggatggt acggggttgg ttcaagcttc aaggaattta tcaataaaaa
     4201 tccagagaat attgctatct tacgagatat gtaccaaaat tggcctttct tccaatcgct
     4261 tctttcaaat gttgatatgg ttttgtcaaa atcaaatatg aatattgctt ttgaatatgc
     4321 taaactttgt gaagacgagc aagttaaggc catctatgag actattttaa atgaatggca
     4381 agttactaag aacgttatct tggctattga aggacatgac gaactcttag ctgacaatcc
     4441 atatctaaaa gctagtctgg attaccgtat gccttacttt aatattctca actatattca
     4501 gttagagttg attaaacgcc aacgtcgtgg agaattgtcc agtgatcaag aacgattgat
     4561 tcatatcacc atcaacggaa ttgcgacagg attgcgtaat tcaggttgat aattttcaag
     4621 agtgaatgct aaaagtgaat atcaaaaaaa ttctaataga ctattgacaa gtagtttaaa
     4681 aatgatataa tttaaccatt cagaaaagta atcatacaaa ctttttagag agtctgtggt
     4741 agctgaaaac agataagtgg caatgatgaa aattgggctg aatgctattt agaatttgaa
     4801 attataaaaa ttcggtaagc acaccttaca gtgcatctcg ttattgcgag actgagcgat
     4861 agggaaattc cctataattg aggtggtacc gcgcatcgac gtcctcacac aagttttttg
     4921 tgtgaggatt tttttgatgg aggttagtat ggaaagaaaa cgatggcatc gcttgtttag
     4981 ataagtgaaa tatgttaaag gaaataaaaa ggagaaacag aatgaaaaat aaacgtttaa
     5041 ttggaattat tgctgcatta gcagtcttag tagcaggaag cttgatttat tcttcaatga
     5101 ataaatcaga agctcagaat aataaggatg agaagaaaat aaccaagatt ggtgtgcttc
     5161 aatttgtgag ccatccatcc cttgatttga tttataaagg gatccaagat ggacttgcag
     5221 aagaaggata taaagatgat caagttaaaa ttgattttat gaactcagaa ggtgaccaaa
     5281 gtaaggttgc gacaatgagt aaacaattgg ttgcaaatgg gaatgacctt gtggttggta
     5341 tcgcaacacc agcagcccaa gggttggcta gtgcaacaaa agacctacca gttatcatgg
     5401 ccgctattac agacccaatt ggtgctaact tggttaaaga tttaaaaaaa ccaggtggca
     5461 acgttacagg ggtatctgac cacaatccag ctcaacaaca aattgaactc atcaaggctc
     5521 tgacaccgaa tgtgaaaaca atcggagctc tttactcaag tagcgaagac aattcaaaaa
     5581 cacaggtcga agaatttaag gcttatgctg aaaaagcagg tctgacagtg gaaacatttg
     5641 cagttccttc aacaaatgaa attgcctcaa ctgtcactgt tatgactagc aaggtagatg
     5701 ctatttgggt tccaattgat aacaccattg catcaggatt tccaacggtt gtctctagca
     5761 atcaaagttc taagaaacca atttatccca gtgcgacagc tatggtagaa gtaggtggtt
     5821 tggcatcagt tgtaattgac caacatgacc ttggtgtggc aacaggtaaa atgattgtgc
     5881 aagtcttgaa aggtgcaaaa ccagccgata ccccagtcaa tgtcttttca actggtaagt
     5941 cagtcatcaa taaaaaaata gcacaagaac taggtattac tattcctgag tctgttctca
     6001 aagaagcagg acaagtcatc gaataaataa ggtagggagg aggagactct tcccattttt
     6061 taaaaagatg aatatagaaa ggattaaata aaatatgatt gtttccatta tttctcaagg
     6121 atttgtctgg gctattctag gtctgggaat ctttatgaca tttaggattt taaactttcc
     6181 agatatgacg acagaaggtt ccttccctct tgggggagct gttgctgtca ctttgataac
     6241 caaaggcgtg aacccatttt tagcgacact tgttgctgta ggagcaggtt gtttggctgg
     6301 aatggcagca ggccttcttt atacaaaagg gaagatccca accttgctct cagggatttt
     6361 ggtgatgact tcttgtcact caatcatgct cttgattatg ggacgtgcga atttaggcct
     6421 gcttggaact aagcaaattc aggatgtttt gccttttgat tcggatttga atcaactctt
     6481 gacaggtctc atctttgtga gtattgttat tgctctcatg ctctttttct tggacactaa
     6541 actcggacaa gcctatattg ctacagggga taatcctgat atggctagaa gtttcgggat
     6601 tcatactgga cgcatggagc tcatgggctt ggtcttatca aatggtgtga ttgcccttgc
     6661 aggtgccctc attgctcagc aagaaggtta tgccgatgtg tctcgaggga tcggggttat
     6721 cgttgtgggg cttgcaagtt tgattattgg agaagttatt ttcaagagtt tgagcttggc
     6781 agagcgtttg cttactatcg ttgtaggttc tatcgcttat caatttttag tgtgggcagt
     6841 tatcgcactt ggctttaata caagttacct tcgtttatac agtgccttga ttttagcagt
     6901 ctgcctcatg attccaacat ttaagcaaac aatcttgaaa ggagccaaat taagcaaatg
     6961 acagcaattg tagaattaaa aaatgcaacc aaagtcgtta aaaatggctt tgatgaagaa
     7021 aagattatct taaatgatgt ttccttagaa atttttgaac aggatttcat cacgatttta
     7081 ggtggaaatg gtgctgggaa gtcaactctc tttaacacta ttgcaggaac cttgtcatta
     7141 accagtggaa ccatccgtat tttgggtgaa gatgttacca agttttcacc agagaagcgg
     7201 gctaagtatc tgtctcgagt cttccaagat cccaagatgg ggacagctcc ccgtatgacg
     7261 gtcgctgaaa atctcctgat tgcaaagttt cgtggtgaaa agcgtggact atttccacga
     7321 cgcttgacta gttataagaa tgaatttcag gcgaccattg aaaaagtagg aaatggtctt
     7381 gagaaacatt tgaatacacc gattgagttc ttatcaggtg ggcaaagaca ggccttgagt
     7441 ctcttgatgg caaccttgaa gcggcctgaa ttactcttgt tagacgagca tactgcggcc
     7501 cttgatccaa agaccagtgt ggccttgatg gaattgacag acgaatttgt caagaaagac
     7561 cagttgacag ctcttatgat tacccaccat atggaagatg ctcttaagta tggcaatcgc
     7621 ttgattgtca tgaaagaagg acgggttatc caagatttga aacaagaaga aaaagcaaaa
     7681 atgaaaatct ctgattatta tcaactcttt gaataaagta gggaaaatga gtgaaatggt
     7741 ttactttttt tctgaaataa agtatactat ataaagtaaa ctatgataac atggaggtat
     7801 tgtgtatggt tgacaaacaa gtcattgaag aaatcaaaaa caatgccaac attgtggaag
     7861 tcataggaga tgtgatttct ttacaaaagg caggacggaa ctatctaggg ctctgtcctt
     7921 ttcatggtga aaaaacacct tctttcaacg ttgcagagga caagcagttt taccactgtt
     7981 ttggttgtgg tcgctcaggt gatgtcttta aattcatcga ggagtaccaa ggggttccct
     8041 ttatggaggc tgtccaaatc ttaggtcagc gtgttgggat agaggtggaa aaaccgcttt
     8101 atagtgagca gaagccagcc tcgcctcacc aagctcttta tgatatgcac gaagatgcgg
     8161 ctaaatttta tcatgctatt ctcatgacaa cgaccatggg ggaggaggcc agaaactacc
     8221 tttatcagcg tggtttgaca gatgaagtgc tcaagcattt tcggattggt ttagcacctc
     8281 cagaacgaaa ctatctctat caacgtttgt ctggtcagta tcgtgatgag gatttcctag
     8341 attcaggact gttttatctc tcggatgcaa atcaatttgt agacaccttt tacaatcgga
     8401 ttatgtttcc cctgacaaat gaccagggaa aggttattgc cttctcaggt cgtatctggc
     8461 agaaaacgga ttcacaaact tctaagtata aaaatagccg atcgactgca atttttaaca
     8521 aaagttacga attatatcat atggataggg caaaaaaatc ttctggaaaa gccagcgaga
     8581 tttacctgat ggaaggattc atggatgtca ttgcagctta tcggtctgga atcgaaaacg
     8641 ctgtcgcatc tatgggaaca gccttgagtc gtgagcatgt tgagtatctg aaaaggttaa
     8701 ccaagaagtt ggttcttgtt tacgatggcg ataaggctgg gcaagctgcg acattgaaag
     8761 cgctggatga aattggcgat atgcctgtgc aaatcgtcag catgcctgat aacttggatc
     8821 cagatgagta tctacaaaaa aatggaccag aagatttggc ctatctatta acgaaaactc
     8881 gtattagtcc gattgagttt tacattcacc agtataagcc tgaaaatagt gaaaatctgc
     8941 aggctcagat tgagtttatt gaaaaaatag ctcccttgat tgttcaagaa aagtctatca
     9001 ctgctcaaaa cagctatatt catattttag ctgacagtct agcatccttt gattatgccc
     9061 agattgagca gattgttaat gagagtcgtc aggtgcaaag gcagaatcgc atggaaagaa
     9121 tttccagacc gacgccaatc accatgcctg tcaccaagca gttatcggct attatgaggg
     9181 cagaagccca tctactctat cggatgatgg aatcccctct tgttttgaac gattaccgtt
     9241 tgcgagaaga ctttgcattt gctacacctg aatttcaggt cttatatgac ttgcttggcc
     9301 agtatggaaa tcttcctcca gaagttttag cagagcagac agaggaagtt gaaagagctt
     9361 ggtaccaagt tttagctcag gatttgcctg ctgagatatc gccgcaggaa cttagtgaag
     9421 tagagatgac tcgaaacaag gctctcttga atcaggacaa tatgagaatc aaaaagaagg
     9481 tgcaggaagc tagccatgta ggagatacag atacagccct agaagaattg gaacgtttaa
     9541 tttcccaaaa gagaagaatg gagtaataat ggcaacaaaa caaaaagaag taacaacatt
     9601 tgacgtacag gtagcagaat ttatccgtaa tcataagcaa aaagggatag caacagatga
     9661 tgaaatcaat gcaagtctgg ttattccttt taccttggac gctgatggga ttgaagatct
     9721 cttgcaacgg attcaggatg caggcatttc tatcacagat aacgaaggaa atccaagtgc
     9781 gcgtgttctt agcaatgaag aagaaccaga actcagcgat gaggacttga ttgggtcaac
     9841 ttctgctaag gtcaatgacc ctgtccgtat gtacttgaaa gaaatagggg tcgttcctct
     9901 cttgaccaat gaagaggaga aagagttggc actggctgtt gaagctggtg atatcgaagc
     9961 caaacaacgt cttgcggaag ccaatcttcg tttggttgtt tccattgcca aacgctatgt
    10021 cggtcgtggc atgcagttcc ttgacttgat tcaagaagga aatatgggct tgatgaaggc
    10081 ggttgacaag tttgactatt ctaaagggtt caagttttca acttatgcaa cttggtggat
    10141 tcgtcaggct atcactcgtg ctattgcgga ccaagctcgt accatccgta tcccagttca
    10201 catggttgaa actatcaata aattggttcg tgaacagcgg aatctccttc aagaattggg
    10261 gcaagatccg acaccagaac agattgctga acgaatggat atgacacctg ataaggttcg
    10321 tgaaatcttg aagattgccc aagaaccagt atctcttgaa actcctatcg gtgaagagga
    10381 cgatagccac cttggagact ttatcgaaga tgaagtgatt gaaaatccag tggattatac
    10441 gactcgtatc gtcttgcgtg agcaattgga tgaaatctta gatactctta cagaccgtga
    10501 agaaaatgtt ctgcgtctac gttttggact agatgatgga aaaatgcgca cacttgaaga
    10561 tgtggggaaa gtctttaacg taactcgtga gcgtatccgt cagattgaag caaaggcttt
    10621 gagaaaacta cgccaaccaa gtcgtagcaa accgcttcgt gattttattg aagactaaga
    10681 gtgaggaaaa tatggcttat acagaagagc aaattgaaaa tatcaaaaca cggattttaa
    10741 cagccttgga agaagtcatc gaccctgagt tgggaatcga tattgtcaat cttggtttga
    10801 tctatgagat tcgttttgac ggtgacacag ggcaaacaga gattgacatg actttgacaa
    10861 ctatgggttg tcccttagca gaccttttga cagaccagat ttatgatgct atgatagagg
    10921 ttccagaagt aacggatact gaggttaaat tagtctggta tccagcctgg acagttgaaa
    10981 aaatgagtcg ctatgcccgc attgccctag gcattaagta aacatataaa agcatgtgag
    11041 agactgttgg aaaagcgagg aaatttcccc tcttttcctc tagtctctcc tttcttttgc
    11101 tgattttatt caaagaaaat gatataatag tagttatgga gaaaaagaaa ttacgcatca
    11161 atatgttgag ttcaagtgag aaagtagcag gacagggagt ttcaggtgct taccgtgaat
    11221 tagttcgtct tcttcaccgt gctgccaagg accaattgat tgttacagaa aatcttccaa
    11281 tcgaggcaga tgtgactcac tttcatacga ttgattttcc ctattattta tcaaccttcc
    11341 aaaagaaacg ctcagggaga aagattggct atgtgcattt cttgccagct acacttgagg
    11401 gaagtttgaa aattccattt ttcttaaagg gaattgtgga acgctatgta ttttcttttt
    11461 acaaccggat ggagcacttg gttgtggtca atcctatgtt tattgaggat ttggtagcag
    11521 ctggtattcc acgtgaaaaa gtgacctata ttcctaactt tgtcaacaag gaaaaatggc
    11581 atcctctacc acaagaagag gtagttagac tgcgcacaga tcttggtctt agtgacaatc
    11641 agtttatcgt agtaggtgct gggcaagttc agaaacgtaa agggattgat gactttatcc
    11701 gtctggctga ggaattgcct cagattacct ttatctgggc tggtggcttc tcttttggtg
    11761 gtatgacaga tggttatgaa cactataaga aaattatgga aaatccccct aaaaatttga
    11821 tttttccagg cattgtatcg ccagagcgga tgcgcgaatt gtatgctcta gcggatcttt
    11881 tcttgttgcc tagttacaat gagctctttc ctatgactat tttagaagct gcgagttgtg
    11941 aggctcctat tatgttgcgt gatttagatc tctataaggt gattttggag ggaaattatc
    12001 gggcgacagc gggtagagaa gagatgaaag aggctatttt ggaatatcaa gcaaatcctg
    12061 ctgccttaaa agatctcaaa gaaaaggcta agaatatttc cagagagtat tctgaagagc
    12121 atctgttaca aatctggttg gacttttatg agaaacaagc cgctttaggg agaaagtaaa
    12181 aagtgaggta atctatgcga attggtttat ttacagatac ctattttcct caggtttctg
    12241 gtgttgcgac cagtattcga accttgaaaa cagaacttga aaagcaggga catgctgttt
    12301 ttatctttac gacgacagat aaggatgtca atcgctacga agattggcaa attatccgca
    12361 ttccaagtgt tcctttcttt gcttttaagg atcgtcgctt tgcctaccga ggttttagca
    12421 aggcacttga aattgctaaa cagtatcagc tagatattat ccatactcag acagaatttt
    12481 ctcttggcct gttggggatt tggattgcgc gtgaattgaa aattccagtc atccatacct
    12541 atcacaccca gtatgaagac tatgtccatt atattgctaa ggggatgttg atccggccga
    12601 gtatggtcaa gtatctggtt agaggtttcc tgcatgatgt ggatggggtt atttgcccta
    12661 gtgagattgt ccgtgacttg ctatctgatt ataaggtcaa ggttgaaaaa cgggtcattc
    12721 ctactgggat tgaattagcc aagtttgagc gtccggaaat caagcaggaa aatttgaaag
    12781 aactgcgtag taaactaggg attcaagatg gtgaaaagac gttgcttagt ctttcgagaa
    12841 tctcctatga aaaaaatatt caagcagttt tagtagcctt tgctgatgtt ctgaaagagg
    12901 aagataaggt taaactggta gtagctgggg atggccctta tctgaatgac ctcaaagagc
    12961 aagcccagaa cctagagatt caagactcag tcatctttac agggatgatt gctcctagtg
    13021 agacggctct ttactataaa gcggcggatt tcttcatttc ggcatcgaca agcgaaacgc
    13081 aaggtttgac ctacttggaa agcttagcca gtggaacacc tgtcattgct cacggaaatc
    13141 cttatttgaa caacctcatc agtgataaaa tgtttggaac cttgtactat ggagaacatg
    13201 atttggctgg tgctattttg gaagccctga ttgcaacacc agacatgaac gagcatacct
    13261 tatcagagaa attgtatgag atttcagctg agaactttgg gaaacgagtg catgagtttt
    13321 atctggatgc cattatttca aataacttcc agaaagattt ggctaaagat gatacggtca
    13381 gtcagcgtat ctttaagaca gttttgtatc ttccgcaaca ggtggttgct gtacctgtaa
    13441 aaggatctag acgcatgttg aaggcttcaa aaacacagtt gatcagtatg agagactatt
    13501 ggaaagacca tgaagaatag aaagaggaac agctatgaaa aaaacaatta atgagaagcg
    13561 gtcgtgataa aaagattgcg ggtgtttgtg ctggggtggc ccattatctg gatatggatc
    13621 cgactatcgt tcaagtcatt tggggtgttc ttacttgctg ttacggagct ggaattgtag
    13681 cttacattat tttatggatt atcgcaccag tagcaactga ctattgaaaa ctagctcaat
    13741 tcatgctaag ataatagaaa atagaatgta acgaaggaga gaaaaatggc atttggagat
    13801 aatggaaatc gtaaaaaaac tatgtttgag aaaataacct tgtttatcgt gattatcatg
    13861 ctagtagcaa gtttattggg aatttttgca actgcaattg gtgccctcag taatctataa
    13921 aatagattca agaaaattta gtgactggga tttcccagcc cttttttaaa gtgagaagaa
    13981 ataatgagta tgtttttaga tacagctaag attaaggtca aggctggtaa tggtggcgat
    14041 ggtatggttg cctttcgtcg tgaaaaatat gtccctaatg gaggcccttg gggtggtgat
    14101 ggtggtcgtg gaggcaatgt ggtcttcgtt gtagacgaag gactacgtac cttgatggat
    14161 ttccgctaca atcgtcattt caaggctgat tctggtgaaa aagggatgac caaagggatg
    14221 catggtcgtg gtgctgagga ccttagagtt cgagtaccac aaggtacgac tgttcgtgat
    14281 gcggagactg gcaaggtttt aacagatttg attgaacatg ggcaagaatt tatcgttgcc
    14341 cacggtggtc gtggtggacg tggaaatatt cgtttcgcga caccaaaaaa tcctgcaccg
    14401 gaaatctctg aaaatggaga accaggtcag gaacgtgagt tacaattgga actaaaaatc
    14461 ttggcagatg tcggtttagt aggattccca tctgtaggga agtcaacact tttaagtgtt
    14521 attacctcag ctaagcctaa aattggtgcc taccacttta ccactattgt accaaattta
    14581 ggtatggttc gcacccaatc aggtgaatcc tttgcagtag ccgacttgcc aggtttgatt
    14641 gaaggggcta gtcaaggtgt tggtttggga actcagttcc tccgtcacat cgagcgtaca
    14701 cgtgttatcc ttcacatcat tgatatgtca gctagcgaag gccgtgatcc atatgaggat
    14761 tacctagcta tcaataaaga gctggagtct tacaatcttc gcctcatgga gcgtccacag
    14821 attattgtag ctaataagat ggacatgcct gagagtcagg aaaatcttga agaatttaag
    14881 aaaaaattgg ctgaaaatta tgatgaattt gaagagttac cagctatcgt cccaatttct
    14941 ggattgacca agcaaggtct ggcaacactt ttagatgcta cagctgaatt gttagacaag
    15001 acaccagaat ttttgctcta cgacgagtcc gatatggaag aagaagctta ctatggattt
    15061 gacgaagaag aaaaagcctt tgaaattagt cgtgatgacg atgcgacatg ggtactttct
    15121 ggtgaaaaac tcatgaaact ctttaatatg accaactttg atcgtgatga atctgtcatg
    15181 aaatttgccc gtcagcttcg tggtatgggg gttgatgaag cccttcgtgc gcgtggagct
    15241 aaagatgggg atttggtccg cattggtaaa tttgagtttg aatttgtaga ctaggagact
    15301 ggtatgggag ataaaccgat atctttccga gatgcggatg gtaattttgt ttccgccgca
    15361 gacgtttgga atgaaaagaa attggaagaa ctatttaatc ggctcaatcc aaatcgtgcc
    15421 ttgagattgg cacgaactaa aaaggaaaat ccatctcagt aaagaagcta aaaaatcccg
    15481 tgcctcatca gacacgggat tttgtggtac gacaggcatg tatagcaaac tgaatctgga
    15541 atagcacagc atatcttcta aaatattgtt ataaattgat ttgaatttca aaattaaatt
    15601 gtttgattct tatttcaatt tgttatagta tatctgatgt caaagttctc ggcgagtcaa
    15661 atagcgattc ccaagcctga ctatcgtgag gtagcggatt aaaatggtct ggggatagac
    15721 cgttttaagt ctgacgctgg aaataagaat tgtcagaaga agggatagcg aaatcgcggc
    15781 tctacgaaca ggaacgtgat aataaggcgt atatagcgga taagagggcc tcaaactcta
    15841 aagtccaaaa aggtagtcgt aacctatatg cgtaaatcac gagagtaatt gaattcgtac
    15901 taagattttc tattttcact gtaacctttt aacgtcctta tatcttgtat acacgaggaa
    15961 agatgtacga tttatcccgt gaggtctatc actataaaga gaaaacgaca gatagaagtg
    16021 atcctgagtc acggttatct ttaaaataga ttgtctgata ggacggtatg tataaaacgc
    16081 ttctgtgaac tgagagaagg ggagaagttc ttgctaaaat ttagttgaac agccgtattc
    16141 cgatacttag ataagagatc tagtcttagc tcctactcag ttttagggga taaaaaaggg
    16201 gcaatagcga ttcgagaaag attatactct tcgaaaatct cttcaaatca cgtcaatatc
    16261 gccttgccgt atgtgtagga tactgactac gtcagttcca tctacaacct caaaacagtg
    16321 ttttgagcaa cctgcggtta gtttcctagt ttgatctttg attttcattg agtattagta
    16381 attcagttac taactcgtca actatgattt atccaataaa attgaaaagg atggaaaaaa
    16441 ggataaattt atgatatact ttattttgaa gaccttatta gaaatcttga aagagtattg
    16501 aaaacttaga atgagaaaaa ttgttatcaa tggtggatta ccactgcaag gtgaaattac
    16561 tattagtggt gctaaaaata gtgttgtggc cttaattcca gctattatat tggctgatga
    16621 tgtggtgact ttggattgtg ttccagatat ttcggatgta gccagtcttg tcgaaatcat
    16681 ggaattaatg ggagctactg ttaagcgtta tgacgatgtc ttggagattg atccaagagg
    16741 tgttcaaaat attccaatgc cttatggtaa aattaacagt cttcgtgcat cttactattt
    16801 ttatgggagc ctcttaggcc gttttggtga agcgacagtt ggtctaccgg gaggatgtga
    16861 tcttggtcct cgtccgattg acttacacct taaggcgttt gaagctatgg gtgccactgc
    16921 tagctacgag ggagataaca tgaagttatc tgctaaagat acaggacttc atggtgcaag
    16981 tatttacatg gatacggtta gtgtgggagc aacgattaat acgatgattg ctgcggttaa
    17041 agcaaatggt cgtactatta ttgaaaatgc agcccgtgaa cctgagatta ttgatgtagc
    17101 tactctcttg aataatatgg gtgcccatat ccgtggggca ggaactaata tcatcattat
    17161 tgatggtgtt gaaagattac atgggacacg tcatcaggtg attccagacc gcattgaagc
    17221 tggaacatat atatctttag ctgctgcagt tggtaaagga attcgtataa ataatgttct
    17281 ttacgaacac ctggaagggt ttattgctaa gttggaagaa atgggagtga gaatgactgt
    17341 atctgaagac agcatttttg tcgaggaaca gtctaatttg aaagcaatca atattaagac
    17401 agctccttac ccaggctttg caactgattt gcaacaaccg cttacccctc ttttactaag
    17461 agcgaatggt cgtggtacaa ttgtcgatac gatttacgaa aaacgtgtaa atcatgtttt
    17521 tgaactagca aagatggatg cggatatttc gacaacaaat ggtcatattt tgtacacggg
    17581 tggacgtgat ttacgtgggg ccagtgttaa agcgaccgac ttaagagctg gggctgcact
    17641 agtcattgct gggcttatgg ctgaaggtaa aactgaaatt accaatatcg agtttatctt
    17701 acgtggttat tctgatatta tcgaaaaatt acgtaattta ggagcggata ttagacttgt
    17761 tgaggattaa accgtagagg tgtttatgaa tatttggacc aaattagcaa tgttttcttt
    17821 ttttgaaacg gatcgcttgt atttgcgtcc tttctttttt agtgatagtc aggacttccg
    17881 cgagatagct tcaaatccag aaaatcttca atttattttc ccaacgcagg caagtctgga
    17941 agaaagtcaa tatgcactgg ccaattactt tatgaagtcc cctttgggag tgtgggcaat
    18001 ttgtgaccag aaaaatcaac aaatgattgg ttctattaaa tttgagaagt tagatgaaat
    18061 caaaaaagaa gctgagcttg gctatttttt gagaaaagat gcttggtcgc aaggatttat
    18121 gacagaggtt gttagaaaaa tttgtcagct ttcttttgag gaatttggct taaaacaatt
    18181 atctatcatt acccaccttg aaaatgaagc tagccaaaga gttgctctta agtctggatt
    18241 tagtttgttc cgtcagttta agggaagtga tcgttacaca agaaaaatgc gggattatct
    18301 tgaatttcgg tatgtaaaag gagagttcaa tgagtaagca tcaggaaatt ctaagctatt
    18361 tggaggaatt accagtaggt aaaagggtca gtgttcgtag catttcgaat catctaggag
    18421 ttagtgatgg aacagcctat cgggctatta aagaagctga aaaccgtgga attgtggaga
    18481 cccgtcctag aagtggaaca attcgtgtta aatcccagaa agttgctata gagagattaa
    18541 cgtttgctga aattgcagaa gtgacttctt ctgaggttct ggctgggcaa gaaggtttag
    18601 agagagagtt tagtaagttt tcaattggtg ccatgactga acaaaatatc ttgtcttacc
    18661 ttcatgatgg ggggctcttg attgtcggag accgaacccg tattcagttg ctagccttgg
    18721 aaaatgaaaa tgcagttctg gttacagggg gatttcaggt tcatgatgat gtgcttaaac
    18781 tggccaatca aaaagggatt cctgttctaa gaagtaagca tgataccttt accgtcgcga
    18841 ccatgatcaa taaagccttg tcaaatgtcc aaatcaagac tgatattctg acagttgaga
    18901 aactttatcg ccctagtcat gagtatggtt ttctgagaga gacagataca gttaaagatt
    18961 atttggactt ggttcgtaag aatcgtagca gccgtttccc tgttatcaat caacatcagg
    19021 tcgttgttgg cgttgtaacc atgagagacg ctggtgataa atcaccaagc acgacaattg
    19081 ataaggttat gtctcgtagt ctatttttgg ttgggttatc gacaaatatt gccaatgtga
    19141 gtcaacggat gatcgcagaa gactttgaaa tggtaccagt tgttcgaagc aatcaaactt
    19201 tgcttggcgt tgtgacgcga cgagatgtca tggagaagat gagccgttcc caagtttcgg
    19261 ctctaccaac tttttctgag cagattggac aaaagctctc ttatcaccat gatgaagtag
    19321 tcattacagt ggaacccttt atgctagaaa aaaatggagt tttggctaat ggtgtattgg
    19381 cagaaattct gacccacatg acccaagatt tagttgttaa tagtggtcgc aatctcatta
    19441 tcgagcagat gctgatctac tttttgcagg ctgttcagat agatgatata ttgcgcattc
    19501 aggcacggat tattcatcat acgagacggt cagctataat tgattacgat atttatcatg
    19561 gtcaccagat tgtttcaaaa gcaaatgtga ctgttaaaat taattagaaa ctaggagaaa
    19621 agatgataac attaaaatca gctcgtgaaa tcgaagctat ggacaaggct ggtgattttc
    19681 tagcaagtat tcatataggc ttacgtgatt tgattaagcc aggcgtagat atgtgggaag
    19741 ttgaagaata tgtccgccgt cgttgtaaag aagaaaattt ccttccactt cagattgggg
    19801 ttgacggtgc catgatggac tatccttatg ctacctgttg ctctcttaac gatgaagtgg
    19861 ctcacgcttt ccctcgtcat tatatcttga aagatggtga tttgctcaaa gttgatatgg
    19921 ttttgggagg tcccattgct aaatctgacc taaatgtctc aaaattaaac ttcaacaatg
    19981 ttgaacaaat gaaaaaatac actcagagtt attctggtgg tttagcagac tcatgttggg
    20041 cttatgctgt tggtacaccg tccgaagaag tcaaaaactt gatggatgta accaaagaag
    20101 ctatgtacaa gggtattgag caagctgttg ttggaaatcg tatcggtgat atcggtgcgg
    20161 ctattcaaga atacgctgaa agtcgtggtt acggtgtagt gcgtgatttg gttggtcatg
    20221 gtgttggccc aactatgcac gaagaaccaa tggttcctaa ctatggtatt gcaggtcgtg
    20281 gactccgtct tcgtgaagga atggtcttaa ccattgaacc aatgatcaat acaggcgatt
    20341 gggaaattga tacagatatg aaaactggtt gggcgcataa gaccattgac ggtggattgt
    20401 catgtcagta tgaacaccaa tttgtcatta cgaaagatgg acctgttatc ttgactagcc
    20461 aaggtgaaga aggaacttat taataaaaag tgaaaagact actggaagtt tattttgata
    20521 aaaaatccag tagatctttt cataataaaa cgcattgtat caagtgttag gggctgatat
    20581 catgcgtttt tctgctttta agattttttc caactctgtt tgtaagcgca tcataacaaa
    20641 gggtctagga ttcagggctc tcctcctata tactattagt aaagtaaaac taagggagga
    20701 tattttagtg tcgcagtcta ttgttcctgt agagattcca caatattgtc gttttgattc
    20761 taaaaagaga aatggaattc tgtttaacgt tcgtattgcc aatcttaaat ttaccttttt
    20821 tagattagac ttcctgcgaa acaaaatatg gtatagtagt tccatgaatt atgaagcaag
    20881 taaacaacta actgatgcac gatttaaatg tcttgttggt gttcagcgta ccacttttga
    20941 agagatgtta gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa
    21001 acctaaatta agcctagaag accttcttat ggccactctt caatatgtgc gagaatatcg
    21061 aacttatgaa
//
LOCUS       DAVLUM010000036        20968 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLUM010000036 DAVLUM010000000
VERSION     DAVLUM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20968
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.036"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(243..461)
                     /locus_tag="VYN42_001202"
     CDS             complement(243..461)
                     /locus_tag="VYN42_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462275.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(707..985)
                     /locus_tag="VYN42_001203"
     CDS             complement(707..985)
                     /locus_tag="VYN42_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462276.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1199..2830)
                     /gene="rlmD"
                     /locus_tag="VYN42_001204"
     CDS             complement(1199..2830)
                     /gene="rlmD"
                     /locus_tag="VYN42_001204"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1462277.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKISTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2904..3878)
                     /locus_tag="VYN42_001205"
     CDS             complement(2904..3878)
                     /locus_tag="VYN42_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1462278.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVENTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3952..4566)
                     /gene="pmp23"
                     /locus_tag="VYN42_001206"
     CDS             complement(3952..4566)
                     /gene="pmp23"
                     /locus_tag="VYN42_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1462279.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            complement(4566..5540)
                     /locus_tag="VYN42_001207"
     CDS             complement(4566..5540)
                     /locus_tag="VYN42_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1462280.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5548..6804)
                     /locus_tag="VYN42_001208"
     CDS             complement(5548..6804)
                     /locus_tag="VYN42_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1462281.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGTPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(6865..7296)
                     /locus_tag="VYN42_001209"
     CDS             complement(6865..7296)
                     /locus_tag="VYN42_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462282.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            complement(7298..7900)
                     /locus_tag="VYN42_001210"
     CDS             complement(7298..7900)
                     /locus_tag="VYN42_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1462283.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7884..8723)
                     /gene="prmC"
                     /locus_tag="VYN42_001211"
     CDS             complement(7884..8723)
                     /gene="prmC"
                     /locus_tag="VYN42_001211"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1462284.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8723..9802)
                     /gene="prfA"
                     /locus_tag="VYN42_001212"
     CDS             complement(8723..9802)
                     /gene="prfA"
                     /locus_tag="VYN42_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1462285.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9799..10389)
                     /locus_tag="VYN42_001213"
     CDS             complement(9799..10389)
                     /locus_tag="VYN42_001213"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1462286.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10513..10695
                     /locus_tag="VYN42_001214"
     CDS             10513..10695
                     /locus_tag="VYN42_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1462287.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10832..12205
                     /gene="mnmE"
                     /locus_tag="VYN42_001215"
     CDS             10832..12205
                     /gene="mnmE"
                     /locus_tag="VYN42_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1462288.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     SQVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12252..13187)
                     /gene="dapA"
                     /locus_tag="VYN42_001216"
     CDS             complement(12252..13187)
                     /gene="dapA"
                     /locus_tag="VYN42_001216"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1462289.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVVEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13243..14319)
                     /locus_tag="VYN42_001217"
     CDS             complement(13243..14319)
                     /locus_tag="VYN42_001217"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1462290.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14661..14733)
                     /locus_tag="VYN42_001218"
     tRNA            complement(14661..14733)
                     /locus_tag="VYN42_001218"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14698..14700),aa:Thr,seq:ggt)
     gene            complement(14833..15342)
                     /locus_tag="VYN42_001219"
     CDS             complement(14833..15342)
                     /locus_tag="VYN42_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1462291.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15340..15436)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15465..15896
                     /locus_tag="VYN42_001220"
     CDS             15465..15896
                     /locus_tag="VYN42_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1462292.1"
                     /translation="MKIPIQKFFNNEILAYLFFGIVTTLVAILLRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15978..16355
                     /gene="mscL"
                     /locus_tag="VYN42_001221"
     CDS             15978..16355
                     /gene="mscL"
                     /locus_tag="VYN42_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1462293.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16397..17491)
                     /gene="hemH"
                     /locus_tag="VYN42_001222"
     CDS             complement(16397..17491)
                     /gene="hemH"
                     /locus_tag="VYN42_001222"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1462294.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESQDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17646..18869
                     /gene="pepT"
                     /locus_tag="VYN42_001223"
     CDS             17646..18869
                     /gene="pepT"
                     /locus_tag="VYN42_001223"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1462295.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHIQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18905..19534)
                     /locus_tag="VYN42_001224"
     CDS             complement(18905..19534)
                     /locus_tag="VYN42_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462296.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            19499..19720
                     /locus_tag="VYN42_001225"
     CDS             19499..19720
                     /locus_tag="VYN42_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462297.1"
                     /translation="MDLFQELICLVQKTFYFFLSICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNIL"
     gene            complement(19991..20339)
                     /locus_tag="VYN42_001226"
                     /pseudo
     CDS             complement(19991..20339)
                     /locus_tag="VYN42_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(20444..20902)
                     /locus_tag="VYN42_001227"
                     /pseudo
     CDS             complement(20444..20902)
                     /locus_tag="VYN42_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6055 a         4362 c         3899 g         6652 t
ORIGIN      
        1 atcaataaaa atttgtttgc taatatctct ttcttctgat tttgtttcaa ggattattgc
       61 tacatcattc atatttttag gtaaatacca accatctggc ttatctgaat atcccttgaa
      121 gcctaattga ttaaaagtag ttatttgacc agtaccttga ttgatgtttt cttcaacttc
      181 attaaagcct atacttctct tgcataatcc ctaacttgat cttctgtcct taaagtcatt
      241 ttctattcct cgtcactaaa attatcttca aaactaataa tatcattagg agtgcaagat
      301 aaagccttac atattctttc taaattctta aatgtaattg gtttatcctt tcccatttgt
      361 gccataacat ttgttgtaag tcctgccata gctattacat ctgttttctt tagtcctttt
      421 tttgctaact gtatccataa tggtttatag ttaagtgcca taatatccct ctttttttct
      481 tcattagatt tatttaatta tagcataaat attgatttca ttcaatctta cattgattta
      541 gtgatttgtt ttagagaatt tgttgtgtta ttccgtcctt attttgccat aaattgtttt
      601 aagtgggacc tcttatcctt accattttta cctcctaatt ttgagtataa aaaagacgat
      661 agagttttta atttctatcg tctgagattt acatattaaa ttttcatcac aaaataagac
      721 tctttaaaga atctttaaat tcattggtat gctgcttaca atatccatta ttaaaatgga
      781 tattgtaagc agcataccaa ctatttattt tttgagtttt aaactttggt agaagtcttg
      841 aactccttat atttacataa ctatttgcct ctataactgt tatgacacga aaccaacaag
      901 caagttcaag cacctccata tctttattca aatgaggact aagatattca caaactttat
      961 cataaacctc tttatctttt ttcataaaag gggcatacaa cttagcaaat ttatcctaaa
     1021 attttttgtt gcctttatca atcatttcaa cgctccttta aatataaaaa tgatcctatc
     1081 aatctttata ttgagcctat tttctaattg ataccttgca agaaaggaat aatagctgtt
     1141 cctataccaa gtaggaatgt aataaattca gaaagtcata tactgtcatt cttttctatt
     1201 aaatcatttt gaagtgtctc aaagcatcca tgatggcttc ttctttttca ggtgtacact
     1261 gtggaataat ttgtttatcc tttttagact tgttgtaatg ttctcgtaat tctattccac
     1321 atttcttttt tatctgtgca atatataatg tcgaaatttt taattcaaat ttattccaaa
     1381 catattcttt gatttgagca tatgttgctt tgctctccgc acttgtcaaa tccatttcat
     1441 ccagctcaat ttcaacactt atgtgcttat cgacatcgag tttggacaaa agtgctaccg
     1501 tctcgacgtg atgcgtttga ggaaatagat ccaccggctg gactttcttc aattcatatc
     1561 ccaactcttg gtatagttta atatcacgcg ccatggttgc gacattgcag gagatatagg
     1621 cgatgcgatc ggctcctgtt tgggcgcttg ctttgataaa gctttctgtc aagcccttgc
     1681 gtggaggatc aaccaagata acggttggtt gaataccttc cttgagccat ttcttcatgg
     1741 cattttcagc cgtgtcacag acatagtggg cattagtaat cttgttcaaa gaagcattct
     1801 tctggctatt ctctactgct tctggaatca gttcaacacc gtagacttct ttgacatgct
     1861 tggcgactga taaaccaatg gttccaatac cagaataggc atcaataatc acatcatctt
     1921 tttttaactc tgcaaagtca atggctgttt gatagagttt ctccgccatt tcagtattga
     1981 cttggtaaaa ggctgggcca gcgatttgga agtcatttcc caacatctgg tccgtaatat
     2041 agtcttgacc ataaagagtg cgccactcct taccaaaaat cgcattggta ttctggtcgt
     2101 tgatattttg catgacagac acaatctctg ggaactgctt gataacttgt tcaatcaatt
     2161 ggtcaacacg aaaaactttt ggacgagttg tcaccaaaac gaccatgatt tgtcctgaat
     2221 agtgaccacg acgcaccaca agattccgaa tcaatccaga ctgttccttt tcgtcataag
     2281 gttttaaatc aaaacgacgg agcaggtctc gaagagctac tacgacttgg tcaatgacag
     2341 gatcctggat aaagaaatct tcaaggggca tgaggttatg cgaattctta cggaaaaatc
     2401 ctgtttccaa gacaccattc actcgacgaa cgggcacctg cgccttattg cgatacttga
     2461 ctggatgttc catatcaagc gtttcagcaa cttctacatc tgcaattcca gcaatcttgt
     2521 agagactgtc cttgacttgc ttggttttaa acttgagctg ttctggataa gaaaggtgtc
     2581 ctaaatccgc gattcctgaa cgcaggtaag ccaaatctag atcttgatta cggtgtggtg
     2641 actggacaag gtatttttca acttttccaa agccaatctt tttattgacc ttgaggacac
     2701 gcatgagaat tttttcactc ggtaaagcat tctctacaaa aaagaccaaa ccatctacct
     2761 tggcaactcc tgccccttca tgggtcaaat caacaatttc aacttctaca atatcatttt
     2821 tctttaacat tcttttctct ttctattggc cgacaaaaaa gacggcaacg ttacggttac
     2881 catccattat accatgaaat ttcttaagaa ccaaaactct tgaagaagtt gacaagggct
     2941 tgccagaggg agcttaagaa gttaccaccg tcctctagcg ccttatccgc atcaaagtta
     3001 aggttgatat ttttaaaact gtcgccagct tgtgatacga tgctttgttt aaggtcattt
     3061 agggttttag tgaaatctgc attgctgagg atatcactct ttgagagatt caaggcaaaa
     3121 ttgatgatga tattgatctg gtttcctgtt atgacctgat caagtttgta attttttaag
     3181 gtattttcaa caatcttgcg tacatcttct tctgtcagat ttcccttgct ttctttagct
     3241 ttggcgagtc ctgacttgat atcagctagg gcaacgttta atttattagc atcatagcct
     3301 gatttgtcct tgttttcagc attgatatct gacaaagcct ttagctcttc ttgagccaaa
     3361 tctttattgg cttgcggcac cttggctcca ttagcttcta gcgaatagta gatcccagcc
     3421 aaagcactct cacctgtaac tggaataggg gctgctacag tgattttggc atgttccata
     3481 cccagcgtta ctgctgcgtt tcggtacata tcctgagtca ccttagtgat attttctggt
     3541 gtttcaatct tgacctcaag tggcgatttg tcacctagct tttgaatctt ggctgatgaa
     3601 tacaactgta agctagagtc attggccaca ttcatgattt tagaataaac atcaggtgtc
     3661 atggtcttga gttctttggt atctgttgag gcattgtagc ccagtttttt aagagtttga
     3721 tttttttggt cttcagatag ggaggaacct aggacatatt caggttggac ataggtttca
     3781 tcgataactt tttgaacatc tgttgctgca tggacgctat tcatagctgt tactgcccac
     3841 aagaccgcag cactagtcag aaagagtttc tttctcatag ggaatttcct cctttacctt
     3901 tctagagtaa tatatctatc ttaaagaaaa cttataacaa aaacacctga actagccaga
     3961 tgttgaaaag agagtgaaac atttgatgat gtaaaggttg agttgcacct gtctagaata
     4021 ataatagttt cctccattta catagagttc ggcaccgtga aaaatggaaa tgggatgaat
     4081 ataactataa gtctttccag tcgtattacc aagcaagggg gcaacagtct cacgagagta
     4141 ctgtttggct agagccaagg tattttcctt gccattttgg gcgataaaat cgatataggc
     4201 aggtccaaaa ttataggctt gaacagctgt ccagatatct acacccttct tctgcgccag
     4261 atagagattg cctgtcagag tttgaatgcc ttgccgaatg ctagaggcat tatcattgat
     4321 ggtgttggtg gaaccacttg cagactcact agactgcata acatcgcctt cttttccttt
     4381 tgtttcagta taaatcatag caagcacaag ctcttcgttt gctggggtgt ctttttcact
     4441 caatatttct cgcaccatgg gttgataggt catgacttgt ttgacatctt gatgaacgcg
     4501 gtaagcttta tagccagcaa aaaggaagac tgctagtaca agcactcttc gaattcgttt
     4561 aaacattatt tactttggat atcctcgata tttttgatta agatagagta ggttccattt
     4621 tcgttttgga taaactcaac agactcggcg tcttgataga cgttattggg aacgatgagc
     4681 tcaattccat ttgataagga gagtttttgg ttttcaaatt tctttaattg gcgactgaca
     4741 tcaatttcat caaattgaac aggttctggt acggcttctt tgacttggtc aataaagctc
     4801 aaacgagccg tcagattgtt gtcaaaaagg tcattagcca atttctcagg tgacaattca
     4861 ttgctttctt ctaggttgtt gaaaatagct gatttgacct tggattgaaa ttgaaaatca
     4921 tctgtgttaa aagattcagc aattctctgg gctgtttttt ccagttcctt gatagatttt
     4981 ttaggagaaa tcttaggagc gacagcaaga agattatctg aaaaatagtt caaaaaagtc
     5041 ccgttgtact tgattcgttt ttcaatcagg tgatacttgc tactctgaag attgaccacc
     5101 aaggcctcat cagctcctgt tccaaatcca ggcaggttat tctgagttag cttgattgga
     5161 ttatcaactt ctcctccgag gtgggtcaag gtctcccgca gggcaattcg caagaaagcg
     5221 aaatgttcta caccttcttt agaaaattga acaaaaatca agtcattggt cttgagattt
     5281 tcagaaatgc taaactcctc tttccagaga ttagccagcg ttactgatgt ctccaacaaa
     5341 tcgtctgtaa tatgattgaa gaagggattt tcttcttcga aaatcccagt cttggcttca
     5401 tctgaataca catgttcaat ttttttacgc aggtattctt cgatttttgg agtaatattg
     5461 agaaacttat ctgctaagaa cagttcggta tcatccggac tgaactggtg aataatggct
     5521 ttcttaatat aaatgtccat aaaagtttta gtcctcgtat agtaggaagg catctgtcaa
     5581 ttctttgact gcacttctca cttcttctaa tacagcctca ttttctgaat tcttaagggt
     5641 tttaatgatg agttcagcca ctttgcgact ttcttcttca ccaaatccac gtgcagtaat
     5701 ggctgctgct ccgatacgaa tcccacttgt cttgaatggt gacaagcttt cgtaagggat
     5761 tgagttttta tttaaggtaa tattgacttc atccaacaag ttttgagcaa ctttgccgtt
     5821 ttctacaact ttagtcacat caacaaggaa gagatggttt tcagttccac ctgaaataat
     5881 acggaaatca gggtcttgca agaagacatc tgccatagcc ttgctgttct taattacatt
     5941 ggcagcatat tccttgaagg ctggatccaa aacttctttg aaggaaactg ccttagccgc
     6001 cacaacatgc tctaaaggac cgccctgaat acctgggaaa atagctgaat tgattttttt
     6061 agcaagttct tcgtcattgg tcaaaatcaa accaccacga ggaccacgaa gggttttgtg
     6121 ggtcgttgtt gttgtgatat gagcgtatgg aactgggctt ggatgaaggc cagccgcaac
     6181 caaaccagcg atatgggcca tgtccaccat gagcttcgcc ccaacagcat ctgcaatttc
     6241 acggaatttt gaaaaatcga taatttgaga ataggctgaa gcaccagcta caatcagttt
     6301 tggttttact tcttgggctt gtttcaagat agcatcaaag tctaagagtt ccgtttcagg
     6361 atccacacta taagaaacaa agttgtaggt ttgaccagag aagctaacag gagtcccatg
     6421 agtcaaatga ccacctgatg ccaaatccat tcccataacc gtatcacctg gctcaatcaa
     6481 ggacatgtaa gccgcacagt tagcttggct tcctgaatgt ggttggacat tggcaaattt
     6541 agcaccgaaa atttcttttg cgcgttcaat agcaagagtc tctacaacgt ctactacatc
     6601 agttccacca taataacggc gtcctgggta accctcggca tatttgtttg tcaagataga
     6661 cccttgagct gccataacag ccttggaaac tacgttttcc gaagcaatca actcgatatt
     6721 attttgttgg cgttcttctt ctttagcaat agcattccag agatcagcat catatgcttt
     6781 aaaatcatct ttgtcaaaaa tcataggtct tctcctttat tgtgtgacta gtccattagt
     6841 ttgattttac aataagaaaa taaactaaaa gatgcgaata aaccgtttct gcactttatc
     6901 acaagtataa ccaacttttt cataaaatgc atgagcaccc agacgatgat tggcagaatt
     6961 taagcggata aacccataac cacatctttt ggcttcttgt tccaaccctt gtagtaaact
     7021 tttaccaata ccttgacctt gcgcttgagg tgaaactgct aaagctaaga tattaaatcc
     7081 tgctttggaa tagagtgatt cgtaaacttc agcgtggaca tatccaagta agacatgatt
     7141 agctgcatcc tcatagccaa gtaggaaatg atgggaatcc tgagacagtc tagctagttg
     7201 gctagccgtt tcctctggac taaaagtata acccaaagcc tcttggttga tgtcacatat
     7261 cgctttcaca tctgtttctt gcaaatctct tagcatttca agcctcctca aaagaaatct
     7321 ctggcaaccg agcaagaata tcttctcgtt taattgcgcc ttggcgtaag attttcacct
     7381 tgtctccaga caaatccaca atagttgaat cctgtccagt tagaaaagca tcgtcttcca
     7441 gacccagaac ctcttggtca aaatccttca gaatttgttc aaaggttaca ccacttgcct
     7501 gacctgagat attggcagac ggcccaatca agggacctgt ctctcgaatt aaatccagtg
     7561 tgatagggtg actgggcatc cgaaatccaa tagttgcaag gtcagaattt acccaatagg
     7621 gaactcggtc attggcttcg agaataatgg tcaagggacc tggcaaaaag gtctctacaa
     7681 gtttttgtag ataagctggc tgattctttg aaaagtgcaa gatgtcctcg aaagaggcga
     7741 tattgagatt gagtgcctta tctctaggac gacgtttgag ttggtaaaca tggtcaactg
     7801 ctttttcatc taaggccttg gaaaaaagac cataaacagt ctctgtaggt agaacgacag
     7861 ctccaccatt ttccaactct tgtctaatcc tgtccatcat caaccacaac catcctattt
     7921 tgaccaaatt ggtccttgag tgttcgaact cttttttcag gaagatgttt cctaaaaagt
     7981 tcgggaacac tttgaccttg cttgtatcca atttcaaggt aaatcttacc accatctttg
     8041 agatagtctt ttgcatcttc cgcaattcta cagtaaatag ctaggccatc ctcgtctgca
     8101 aagagagcta gatgaggctc cgaatgcaaa acattcaagc ctacctctga ctcatcttca
     8161 cgagagatat agggtggatt ggatacaatt atatcatatt tttcagaaat ttctgcaaaa
     8221 caatcagatt ttttaaaaaa tatattaaga ttttgattgc tagcattctc tgatgcaagc
     8281 tctaaggcct cttgagaaac atctgctgct gtcactgacc aatctggtct attttttgct
     8341 agagcgagag caatagctcc actacctgtt ccaatatcca gaactgagag attcgtctca
     8401 agattttcag ttagaataag ctccactaac tcctctgttt ctggacgagg aatcaaaacc
     8461 cgttcatcca cctttaaatg cattccataa aaatctgcct gtccaatgat gtactgagct
     8521 ggcttgtgag ctgctagttg ctggtaaata tcttctacaa attgtttttc ttcctctgtt
     8581 gtcacctcct gctggagggc aaaaataaag tctgtaaaag atagattttt cagactacga
     8641 tagacaaaag agaggctttc cgcttcctct ccttgtctta tcaactcttc ttcaaaattt
     8701 gaaaataatt gagctaattt cattatttgt ttaattcttc tagtttttgt gtttggtcat
     8761 aaagcaccaa ggcatccaca acttcgtcca atttaccaga caaaatcgta tctagttttt
     8821 ggagggtcaa gccgatacgg tggtctgtga cacggttttg tgggaagtta taagttcgga
     8881 tccgttctga acggtcacca gtaccgattg tcgacttacg ctcagcgtct tgttcatcct
     8941 gagcaatctg agcaaagtgg tcagcgacgc gtgcacggat aatcttcata gccttctcgc
     9001 ggttcttctg ctgggtacgt tcttcctgca tctcaacctt gatattggtt ggcaagtgaa
     9061 cgatacgaac ggcagtcgca accttattga cgttctgtcc accagcacca gaggcgtgat
     9121 agatgtcgac acgaaggtct tttggatcaa tgtcgtattc aacctcttca acttctggca
     9181 taacaagaac tgtcgctgtc gaagtatgaa cacggccttg gctttctgtc acaggaacac
     9241 gttgcacacg gtgggcacct gattcatact taagcttaga gtatacagac tgacctgaaa
     9301 ccatagcaac cacttcttta aaaccaccga caccattcat agaggcttcc atgacttcaa
     9361 agcgccaacc ttgggcttcc gcatactttt ggtacatagt tagcaaatct ccagcgaaaa
     9421 gtgccgcttc gtctccacca gctgctccac ggatttcaag gatgatattc ttgtcatcgt
     9481 ttggatcctt tggaaggagc aaaattttca gtttttcttc atattcttct ttttcagcct
     9541 tggcatcttt gagttcttgc ttggccattt cttccaagtc cgcatctccg cctgattcct
     9601 taatcatctc ttcggcatcg acgatatttt gaaggacttg tttatactca cggtaggcta
     9661 ttacggtgtc acgattggaa gcttcttctt ttgaaagctc cataaaacgc ttggtgtctg
     9721 aaacgacatc agggtcactc agcaattctc ctagttcttc ataacggtct tctacagctt
     9781 gtagttgatc atagatgttc atttttcttc attctcctta ttgatttcag gggcaaaata
     9841 atgtttacgg caaaccgaga tataggtttc attaccacca atttggatct gttctccatc
     9901 gtaaacgggc agtccatcct gtgttcgcaa caccatggtc gcctttttct tgcaatactg
     9961 acagatggtc ttgatttcgt caatcttgtc tgctaaaagc aagagatatt tggaaccttc
    10021 gaacaattca ttgcgaaagt catttttcaa gccaaaagcc atgacgggta tgtctaactc
    10081 gtccacaaca cgagctaggt cataaacatg gtggcgtttg agaaactggg cttcatcgac
    10141 caacacacag taaggttttt ctggtaggcc tcggatatag ccaaagatat ccgttgtttc
    10201 ctcaatcgca agggcagggc gtttcatgcc aattcgactc gacacatagc caacaccgtc
    10261 acgcgtatcc agagctgaag tcataatcac aacacctttt ccttgctcct catagttata
    10321 ggccaccttg agaatctcga ttgtctttcc agagttcatg gtcccataac gatagtacaa
    10381 ctgtgccatg tttcttgctt cacgtccatt tctaaatttt tgctacattc tagtatatca
    10441 taattttctt aagctttaaa cggcaaaatg tggtaaaata gaagaaatca aaaactagtg
    10501 gaggaagcta ttatgccatt tgtacgcatc gatttatttg aaggacgcac gctcgagcaa
    10561 aagaaagctc ttgctaagga agtaacggaa gcggttgttc gcaacactgg agcacctcaa
    10621 tctgctgtcc atgtcatcat caacgacatg ccagaaggaa cttacttccc acaaggggaa
    10681 atgcgtacca aataagctag cttaagcaga attgcttagg ctttttcaat ctccaagtag
    10741 cattcattga agaaatatcc taaatttgtt acaatttgaa aagaaacttg gagaatttcc
    10801 aagaaaatag ctattaatta aaggaaacat tatgattaca cgtgaatttg ataccatcgc
    10861 tgctatctct actccactag gtgaaggagc tattggtatt gtccgcctga gcggaacaga
    10921 cagttttgct attgcgcaaa agatttttaa aggaaaagac ttgagtcagg ttgctagcca
    10981 cactctcaac tacggtcaca ttattgatcc tctgactggt aaagtcatgg acgaggttat
    11041 ggttggggct atgaagtctc caaagacctt cactcgtgag gatattatcg agattaacac
    11101 ccacggtggt attgcggtga ccaatgagat tctccagcta gctatccgtg aaggagctcg
    11161 gttggcagaa cctggtgaat ttaccaaacg tgccttttta aacggtcgcg tagatttgac
    11221 acaggccgag gcggtgatgg atatcatccg agccaagaca gacaaggcca tgaacatcgc
    11281 ggtcaaacaa cttgatggtt ccctttctga tcttatcaat aatatccgtc aagaaatcct
    11341 taacacactt gcccaagttg aggtcaatat cgactatcct gagtatgacg atgttgagga
    11401 agccactact gctgttgtcc gagagaagac aatggagttt gagcaattac taaccaaact
    11461 ccttaggaca gcacgtcgtg gtaaaatcct tcgtgaagga atttcaacgg ctatcattgg
    11521 acgtcccaac gttgggaaat caagccttct caacaacctc ttgcgtgagg acaaggctat
    11581 cgtaacagat atcgctggga caacacgaga tgtcatcgaa gagtacgtca acatcaatgg
    11641 tgtacctctc aaattgattg atacagccgg tattcgtgaa acagatgaca tagtggaaca
    11701 aatcggtgtt gagcgttcga aaaaagccct caaggaagcc gacttggttc tactagtgct
    11761 aaatgccagt gaaccactga ctgcgcaaga cagacaactt cttgaaatta gccaagatac
    11821 caatcgcatt attctactta ataaaaccga cctgccagaa acgattgaaa cttcgaaact
    11881 acctgaagac gttatccgta tttcagtcct taaaaaccaa aacatcgaca agattgaaga
    11941 gcgaatcaac aacctcttct ttgaaaatgc tggcttgatt gagcaagatg ctacttactt
    12001 gtcaaacgcc cgtcacattt ccctgattga aaaagcagtt gaaagcctac aagccgttaa
    12061 tcaaggtctt gagctgggga tgccagttga tttgcttcaa gttgacttga ctcgtacttg
    12121 ggaaatcctc ggagaaatca ctggggatgc tgctccagat gaactcatca cccaactctt
    12181 tagccaattc tgtttaggaa aataagaaaa atccatgatc cttcattcgg tcatggattt
    12241 tattgtcttt attagtaatc tggtcttaag acccctgtta cagttgcctt agttgcttcg
    12301 tagtcgccat ctacgacaac cttgataatg cgtttggcat cttcttctgg tgctggaaca
    12361 agaggtagac gagtgggtcc agcttcaaat cccatatagt taagaattgc cttaactgga
    12421 gcaggacttg gataagagaa gagagcatta accttaggaa tgaatttacg ctgaattgct
    12481 gcggctttct tcatatcgct ttctgcaatg gcagtaaaca tctcgtgcat ttcatcccca
    12541 tttgtatgag aggcaacaga aataacccca tccgccccaa ggttcatggc atggaaagca
    12601 tctccatcct cacctgtata aatcaagaac tcttcaggct tgtgctcaat caagtaagcc
    12661 atattagcca agctagtaca ttctttgaca ccgataatat ttggatggtc agccaagcga
    12721 agcatggttt ctggagtcaa ttcgacaact acacgccctg gaatgttata gataataatt
    12781 ggtaggtcag aagcatctgc aatagtctta aagtgctgat acatcccttc ttgagaaggt
    12841 ttgttgtagt aaggaacaat agcaagccca gctgcgaaac caccaaattc cactacttct
    12901 ttgacaaact caatagagtc acgcgtatca ttagtaccta cacccgcaat caaaggaacg
    12961 cgtccattga caaccttttg tacagccgca aacaactcca actcctcatc gtgggtcaaa
    13021 gttggactct cagcagtcgt tcctgcgaga agaattccat ccgtatgatg ggccaataaa
    13081 tgctcaatca aggctggaat agcatcaaag ttaatagaac catcctcatg aaagggggta
    13141 ataaaggctg taatgatttt acattctttt aaatcttgat aagacatgaa aacacctctc
    13201 tatttcaaag aaggagttca tctgaactcc taaacgatat gactatttta attcaaattt
    13261 caattcggct gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa tctgaactga
    13321 gttccaagca gcacctttga gaaggttatc tgaaacaacc cacatgtgaa ttcctttttc
    13381 tgcatccaag tctttacgga tacgaccaac aaaggtatca cgcgaaccaa ctgcattgat
    13441 agcttgagga tagatttgat gagctacatc atcttcaaga acagcacctg ggaaggctgc
    13501 gatagctgct tttacttctt cgattggagc cacttctttt gtttcgatat aaacagactc
    13561 agagtgagct gacaagactg gaatacgcac acatgttgca gatactgcaa tgctatcatc
    13621 ttccataatt ttcttagttt ccttggtcat cttcatctct tcgtacgtgt aatcattatc
    13681 agtgaaaaca tcaatttgtg gaagagcgtt aaaggcgata ggataatgtt tcttgtcacc
    13741 acctgaaggc aaaatttccg catgcaaatc acatggtttc acaccatcat tcaagacttc
    13801 acgaagttca cgttgtgtct caagaattgc tcccatacca gcacctgaaa cggcttgata
    13861 agttgaaaca atgatacggt ccaagcccca tttttggcga accggctcaa gagccaccat
    13921 catttggatt gttgaacaat tagggcaggc aatgattccg ttgtgggcat caagtgcatg
    13981 agcattgacc tctggaacaa ccaaaggaac atctggattt tgacggaaat aagatgtatt
    14041 atccactact accacgccag cttttactgc gtatggtgca tacttagctg atgtagaact
    14101 acctgctgaa aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg tttcttcaat
    14161 tgtaatatct tgatctttaa atttcaatga cttacctgct gaacgtgcag aagcaaggta
    14221 acggatttta tcgattggaa gtgttgattc ttccaacatt tttatcatct gagcaccgac
    14281 agcacctgtc gcgccgacta cagcaactgt atatcccata aataacctct ttcggaattt
    14341 tctaaaaatt tctataatag aagtattata ctactttttc catgaattgc aaagcttttt
    14401 catcattttt tggaaaataa aaatcccagt cgctagacta gggactaaga ggcatcttca
    14461 tgtgatgagc aggttcacac aactcatcaa ggtccgctcc tgcgttatga cctccttatg
    14521 ctcaatagta gtccgaagac tacctatcga ctcatcgcat attctatatt actagagata
    14581 cttgattttg tcaataagaa attttttcga tcgagtataa caaaaaactc tcgtattcaa
    14641 gagtttccct atacatatca tgctaattgc cgggatcgaa ccggcgacct catccttacc
    14701 atggatgcgc tctgccaact gagctaaatc agcttactta agaagtatac tatattcaga
    14761 aaaacttgtc aagtttcctt agaaattttc cataggaaaa agccaggtaa gaactaccta
    14821 gcttatcttc ttctatttac ttaaatcaat tcgacgacca attttaccaa taataatcgc
    14881 cccaataatc aatgaagcaa attcaccgat tcctgttgta aaccaagtaa ggaagaatgg
    14941 taattctgct acaatattta actctgcagc gatagtaaac atggaaattg aaaagaggat
    15001 tgaaaagaag aaatgatctt ttcgaatcaa tccgttaaag aggtaatcct tgctatattt
    15061 tgcaaaaagc caaacaccta aactgaggaa tactaaggtt gaaccaccac caacaaagac
    15121 atctagcagt ccgaagctaa agaaattagc aatcatacaa ccgatggtaa ctccgatgat
    15181 gtacttagga ttgtaaaaag ccataaagtt catcatttct gaaatacgaa actgataagc
    15241 accatagctg atggcattta ggggcggtgt gacagtcaaa acgacgtaga tagcagcgac
    15301 gattgcaata tctgcaacat cacgaatagt taattttttc atcttttctc ctttggcggt
    15361 tgcccgcgtg taatatgctt ggtgaaagaa gctaagcacc aagggttgct ttattcaacc
    15421 ctactagtat agcacaatag cctgctttat gctatactta acacatgaaa attcctattc
    15481 aaaaattttt taacaatgaa atcttagcct atctcttttt tggtatagtg actactcttg
    15541 ttgctatact attacgatta gtcatttatc agctaagtca tcaagaactc cttgctacgg
    15601 ccttggcaaa tattatcggt attttatttg cctttatcac aaatgataca attgtattta
    15661 agcaaaaaaa gaaaaataga cttatccgtt tagtgaaatt ttctcttgct cgcctttcta
    15721 cttttctgtt agacttgttt ttaacttttc tctttgtaac ccaatttcct cacatcatag
    15781 ggcaattcgt aactgaaaac attgataaga taaatgctat tgaaacaata attgcacaaa
    15841 tattcattat tatcatcaat tatatcttga gcaaggtcta tatttttaga aaataatgct
    15901 ccatttatga gccttttaat tgccttctat aatgatttag gatacaatga aacacgaaac
    15961 attgaaagga aaacagtatg ttaaaaaatc taaaatcgtt cttgcttcga ggaaatgtta
    16021 ttgaccttgc tgtcggtgtt gtaattgcct ctgcttttgg tgctatcgtt acttcacttg
    16081 taaacgacat tatcactcct cttattttaa atcccgcttt gaaagctgct aaagttgaac
    16141 gtatcgctca actttcttgg catggagtcg gctatggtaa cttcttaagt gctattatca
    16201 attttatctt tgtgggtacc gccctcttct ttattatcaa gggcattgaa aaagcacaga
    16261 aactgactgg cataaaggaa gaaaaaactg ccgaaaaaaa accaaccgaa ttggaagtcc
    16321 ttcaagaaat aaaagctctc cttgagaaaa aataatcgat taaaaggatc tagcgcaaag
    16381 ctaaatcctt ttttctttac tctttgggta acttgcctgc tttttcaagc atttttttga
    16441 taagataagg catcttaaca ttctcccgcc cttttttctc aatcagtttt ttcacaaatt
    16501 ctggcatttg taaatcttga gattcggcta agatattttt agtctcatct gaaggcacta
    16561 actcatcaaa ggtttcttct tctgggagaa attccttaaa ctcttgattt tcattgactc
    16621 taactgtatt gaccaaggca tcaatcaaac gagaatctgt atttggcatt ggtggacgat
    16681 ggtagtttac cccaaattcc tgacataaat cataacattc cacatcattg tcaaacaaga
    16741 cctcaatatg ctcactgatg aaactaatag gtacaaaaat ataatggtct ggatgttctg
    16801 tctgttctct gagatactcc aaaacatctg gtttaatcca tggaatacca atatcactct
    16861 cactctgcca agtgttggta tattgttctg aactcaagcc cagtttttca gcgactagct
    16921 tgctattttc gaaaatttgg tctatataag gatctccaaa gtccaaggca aaaataggca
    16981 cactatgggc tgaaaagatg actttaaagc tgtcttgctt tacttcttct tttaaaatct
    17041 tagcaatttc atctgcccaa tagtttaaga gcgcttcttc ctgataccag tccttaatga
    17101 ccaaaaattg aatttgtttg ctttctaaaa atttttcata gcccatgaca gagtagaaag
    17161 aataatgggg ctccaaaatc aagcaaatac actgttcaat tccgtctgct tccatttgac
    17221 cgatcacatc tggaataaag ggactggaaa acttattagc aaagtagaca ctgtattcat
    17281 tccccagcct agcttctacc aaggcaacct cttgacgggt aattttttgc agaggcgtgc
    17341 ctccaattcg tacataatta tcatagagag tctgaatctc gtggtcttgg ggtctcatcc
    17401 cacgacgaat atttgtgaaa aaatcagcta caccttcaaa ggtaatctct tctggtgaac
    17461 cgaaggtcat cattaaaatt gcttttttca tgactgcttc cttgtgatgt ttttatcaag
    17521 tttattttat cattaattca tcgataagta aacgctagca tagggacatt ctcaatcttc
    17581 tgtcttttgt ttttctcttc tttctatgat acaatggaaa aaataaattc aaaaggagtt
    17641 tttttatgac ttatccaaat ctcttggacc gcttcttaac ctacgttaag gtcaacacgc
    17701 gctctgatga acactctact actactccaa gtacacagag tcaggttgac ttcgcaacaa
    17761 atgtcctaat tcctgaaatg aaacgtgttg gactgcaaaa tgtttactat ctaccgaatg
    17821 gttttgctat tggaaccttg ccagccaacg atccgtcttt aacacgtaag attggtttta
    17881 tatcgcacat ggatactgct gattttaatg ctgaaggagt caatccacag gtaattgaaa
    17941 actacgatgg tggtgtgatt gaactaggga attctggttt caaactcgat ccagctgact
    18001 tcaagagtct tgaaaaatat ccaggacaaa cgctcatcac aacagatgga acaaccttgc
    18061 taggtgctga tgacaagtca ggaattgctg aaattatgac agccattgaa tatctaactg
    18121 ctcatcctga aattaagcac tgtgagattc gtgttggttt tggtccagat gaagaaatcg
    18181 gtgttggtgc caataaattt gatgcagaag attttgatgt ggattttgcc tacactgttg
    18241 atggtggtcc actaggtgaa cttcagtacg agactttctc agccgctggt gctgaattgc
    18301 atttccaagg ccgtaatgtc caccctggta ctgccaaagg gcagatggtc aatgcccttc
    18361 agctagcaat tgattttcat attcaacttc cagaaaatga ccgacctgag ttaactgaag
    18421 gttaccaagg tttttaccat ctaatggatg tgacaggtag tgttgaggag gcgcgtgcaa
    18481 gctacatcat tcgtgatttt gaaaaagatg cctttgaagc gcgtaaagca tccatgcaat
    18541 ctatcgctga taagatgaat gaagaacttg ggagcgaccg tgtcactctc aacttgacag
    18601 accagtacta caatatgaaa gaagtcattg aaaaagatat gactccaatt accattgcta
    18661 aagccgttat ggaagatcta ggtatcacgc ctattatcga accaatccgg ggtggaacag
    18721 acggctctaa gatttccttt atgggaatcc caactccgaa tatctttgca ggtggcgaaa
    18781 atatgcacgg acgttttgaa tacgttagcc ttcagactat ggaacgtgca gttgatacca
    18841 tcattggcat cgtagcttat aaaggctaaa aagacgaggt ggctcagcta cttcgccttt
    18901 ctttttattc tactggtttt tcttgatttc cagtagttgt agaagattct gttgtttcat
    18961 tttctgaagt tgattcagca ggtttagaat ctcttgtatt gcttggtttg ttttcgtcgc
    19021 tagcagtttc aatgttagat tctgcagttg cgtttggttg gttctcagca ctggtgttat
    19081 cactatttgc ttcagcattt cttgctggac ttgtttcttc acttgcgcta gcttttgact
    19141 ggatttgatg attcaaaact agaatagctt ttgtcgattc aagtaaagct gttttgtctt
    19201 tactcttagc agaaagttga tctaataatg catccacctt atcaaagtcc gcatcagatc
    19261 cattattact ttctaaataa gagtgaagcg acatgagaat atcgtagagt ttttgataga
    19321 gtacaagtgt ctgagaatct tgctcagcat tttccttttc ttgttgaagg gcgctagcga
    19381 tacgagtcaa aacatctttt acctgactgt ttacttcatc caagtctgca tcagccttgt
    19441 ttgtggcagc ttttagattt tctacttctt ctgccaagga ttgtctgatt ccttcttcat
    19501 ggatttgttc caagagttga tttgccttgt tcaaaagact ttctacttct tcctttctat
    19561 ctgtcgcaga ttattggttg ctatctacca tgtactccta aaacaggaga gttataatcc
    19621 aagattacaa ggccttacag aaataagaaa tccagataag acaatgttcg tccaagacgc
    19681 tattcgcttc gcacagcagc acggattcaa tatactttaa ttttaaagtt taggtgtcaa
    19741 gacctctttt tagtgtaccc aaaatttaga gaagtaatca atcaactaac ttttattttt
    19801 ttcaaacttt cagtaaactg acctaaagct aactcaatct gtctttgtag atgcttctgc
    19861 tatcagctag aagttgatct acttttgcca agactgcctt ctcatcaaaa gttccaggtt
    19921 gatagttgga ttgcagggat ggaatcttgt ttttcaaagc cgcttcatat cccttagttt
    19981 gaaccttgat gtagtgattg tggtcgccat gaggaatcac aaaaccttct gaatcttcac
    20041 ttataattcg attggcatca aaaaccatga ccatcttctt cctcatggtg gacatgtagt
    20101 gacggattac ttaatacaga actagaagaa cttcctacct cttccgtgtt agagtgtgat
    20161 gggggattgt taagagatga cttaggaata tagtgatagt gttccccatg tcttactata
    20221 taagcatcac ctatatctct gacaatatca ttagggttaa agacatatgt ggctgctaat
    20281 tcacctgccg acaagtcact ctcaggaatg aaatgatagt gaccaccatg tggtactatt
    20341 agtaggttga aatagaatat gagcaaattg ataaggggat tttaaagtaa tttctaacaa
    20401 tgatttagaa actatgatgt gctattctaa attcaactca ctatatataa ccatcatcgg
    20461 tagtataacg tccctgtaat tttgctacag atacttctgc actagctcct ttatcgtctt
    20521 taccatgttc ttgtttttgg cgattgattt catcttttgt tcgtacattt tctgcatgag
    20581 cttgatcttt aaggtaaaca taatactttc catctacctt aataatatat cctcccttaa
    20641 cctaactgac gatatcttga tctttcggct gatagttggg ggctttcatt aatagctctt
    20701 cactaaagag cgcatcaaaa ggaactttac cattatagta gtgataatga tcgccatgag
    20761 aagttacata accttgacct gtaatcttaa taacaatttg ttttgcttga attccttctt
    20821 tttgactaac ctagtctgga gtcaaatttt cagtcttctt agtgtcttta ttactgttta
    20881 catatgaaac acgattttta tctgtattgg cctgttagct atgttggttc agagcataaa
    20941 cacacagact taaggaaagg ataacaac
//
LOCUS       DAVLUM010000037        20930 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLUM010000037 DAVLUM010000000
VERSION     DAVLUM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.037"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(109..978)
                     /gene="rsmI"
                     /locus_tag="VYN42_001228"
     CDS             complement(109..978)
                     /gene="rsmI"
                     /locus_tag="VYN42_001228"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1462298.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(981..1298)
                     /gene="yabA"
                     /locus_tag="VYN42_001229"
     CDS             complement(981..1298)
                     /gene="yabA"
                     /locus_tag="VYN42_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1462299.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1338..2228)
                     /locus_tag="VYN42_001230"
     CDS             complement(1338..2228)
                     /locus_tag="VYN42_001230"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1462300.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2225..2863)
                     /locus_tag="VYN42_001231"
     CDS             complement(2225..2863)
                     /locus_tag="VYN42_001231"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1462301.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(2979..3776)
                     /gene="proC"
                     /locus_tag="VYN42_001232"
     CDS             complement(2979..3776)
                     /gene="proC"
                     /locus_tag="VYN42_001232"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1462302.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(3780..5042)
                     /locus_tag="VYN42_001233"
     CDS             complement(3780..5042)
                     /locus_tag="VYN42_001233"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1462303.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(5052..6182)
                     /locus_tag="VYN42_001234"
     CDS             complement(5052..6182)
                     /locus_tag="VYN42_001234"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1462304.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(6262..8145)
                     /gene="cbpE"
                     /locus_tag="VYN42_001235"
                     /gene_synonym="pce"
     CDS             complement(6262..8145)
                     /gene="cbpE"
                     /locus_tag="VYN42_001235"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1462305.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELSVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKIGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(8148..9035)
                     /locus_tag="VYN42_001236"
     CDS             complement(8148..9035)
                     /locus_tag="VYN42_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1462306.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9025..9486)
                     /locus_tag="VYN42_001237"
     CDS             complement(9025..9486)
                     /locus_tag="VYN42_001237"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1462307.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(9483..10391)
                     /locus_tag="VYN42_001238"
     CDS             complement(9483..10391)
                     /locus_tag="VYN42_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1462308.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            10384..10581
                     /locus_tag="VYN42_001239"
     CDS             10384..10581
                     /locus_tag="VYN42_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462309.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSSQPY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(10633..11304)
                     /locus_tag="VYN42_001240"
     CDS             complement(10633..11304)
                     /locus_tag="VYN42_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462310.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKSLYYPILVHILINITAFWNVWLL
                     LFSGS"
     gene            complement(11358..11579)
                     /locus_tag="VYN42_001241"
     CDS             complement(11358..11579)
                     /locus_tag="VYN42_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1462311.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            11850..12659
                     /locus_tag="VYN42_001242"
     CDS             11850..12659
                     /locus_tag="VYN42_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1462312.1"
                     /translation="MIKLLALDMDGTLLNEVKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGTASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(12840..13715)
                     /gene="aguB"
                     /locus_tag="VYN42_001243"
     CDS             complement(12840..13715)
                     /gene="aguB"
                     /locus_tag="VYN42_001243"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1462313.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(13725..14810)
                     /gene="aguA"
                     /locus_tag="VYN42_001244"
     CDS             complement(13725..14810)
                     /gene="aguA"
                     /locus_tag="VYN42_001244"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1462314.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(14807..15934)
                     /gene="nspC"
                     /locus_tag="VYN42_001245"
     CDS             complement(14807..15934)
                     /gene="nspC"
                     /locus_tag="VYN42_001245"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1462315.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(15934..17193)
                     /locus_tag="VYN42_001246"
     CDS             complement(15934..17193)
                     /locus_tag="VYN42_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1462316.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWVYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(17190..18050)
                     /gene="speE"
                     /locus_tag="VYN42_001247"
     CDS             complement(17190..18050)
                     /gene="speE"
                     /locus_tag="VYN42_001247"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1462317.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            complement(18081..18218)
                     /locus_tag="VYN42_001248"
     CDS             complement(18081..18218)
                     /locus_tag="VYN42_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462318.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            18305..19021
                     /locus_tag="VYN42_001249"
     CDS             18305..19021
                     /locus_tag="VYN42_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV1462319.1"
                     /translation="MLYVGIDIAKNKHDVTALNVQGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIKKFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHNNRQVELKILTRHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQ
                     IEIRNSLDKTIDFSYSLSFS"
     gene            complement(18987..20462)
                     /locus_tag="VYN42_001250"
     CDS             complement(18987..20462)
                     /locus_tag="VYN42_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1462320.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         6079 a         4872 c         3812 g         6167 t
ORIGIN      
        1 gtttttattt attcactact caatcaattc tattatttag actccgaata ttatcatcac
       61 taattaagtt aaacagaaac agacagaatt attacatcct gtctcccttt attgtttttc
      121 ttcccagtcg tggtaggcag cgtagagctg acttttattc cactggtaaa tcttagcgac
      181 ttccttgata gcttggtttt tcttcacacc ttgctggatg cgggtttgaa tttctacgaa
      241 caagtcttcc tcgtcctttt cctccacacc ctgactggca ccctcaacaa tgagaagaca
      301 ttcgcccttg agtggcgttt cagcaatgct ttctaataac tcagagatag tacctcgttg
      361 gtattcttca tagattttgg tcaattccct gaccaagaca acggagcggt caccgtagac
      421 ttctaacata ttttccaacg tgtctgctac acgatgaggt gattcataaa aaatctgtgt
      481 ttcaggataa tcttttttca agccaaaaaa ttgcttctgc tgacctgatt ttctcggtaa
      541 aaaaccgtaa aagatatgtg gctgtggcgc taaaccactg gcaatcaagg cagaaattcc
      601 tgcagaggca cctggaactg tcacaactgc aatttcttcc tcaatagctg ccttaactaa
      661 atcatgacca gggtctgaaa tgctaggcaa accggcatca gagacctgag caatactttg
      721 ccctgctttc aagaaaccaa tcaaatcagg aattttttcc ttggcattgt gctcatgaaa
      781 actgatctgc ttggtggaaa tgtcaaaatg cttgagcaaa agacctgtat tgcgcgtatc
      841 ctcagcagca atccaatcta cttctttcaa ggtctggata gctcgaaagg tcatatcatc
      901 tagattgcca atcggcgttg ccactagata cagcttgcca tagggagact gccccttaaa
      961 acttttttga atctgcatgc ctactccctg tatagcaact cgtcacaaaa catacattcc
     1021 tcgtcctgct ctcgacgttg tccataaaaa tcattacata cgtgaaatcc atcacggtaa
     1081 atgcgacgga cactttcacg aacatgcttg gccttgacag gagcatctgc ttccacctca
     1141 cccaagcgtt ctcgcaactt agaattttcc aaacgaagag ctgtattttc ctctaccagg
     1201 ctcttgagat ttttcttgat ggcttccaca tcggccaagg ttaccaataa ctgttgggaa
     1261 aaatcatcca gcgcgtcaaa taattctttt ttgtccataa aacagccctt tcctttcttt
     1321 atcattcatt tttgagttta tatttctttc aagaccagat attccatggc attttgaaag
     1381 ctgacattag cttgccacat ttttctagct tctagtaaat cttgtagaat cactcttact
     1441 cttacctgca agaggtcctg cccacagaga acttcaagaa tccgtaaaac ctgatcctgt
     1501 ttttccttat catctgccaa gttggctaat ttggcaacct gtagataact ttcttttttc
     1561 ttagctacta accaagtcag caggcgttca ctttcatcga ccaaggtcca aaaacttgcc
     1621 tgatgtgcca acttttctgc ttcagctcgc gattgactaa acttagctaa aagagtcgct
     1681 tttttcttaa caagtcccat ttgttctaag agtaagataa gtttttcttc ttgcttttta
     1741 aagtggaaga tctgagtccg acttcggatt gtcggtaaca tcttttcctc atcgctagtc
     1801 aagaagaaaa tataaacttc actctggggt tcttcgatga ccttgagcag agaattggct
     1861 gcgttgggat gcattttatc cgcttgctcg atgataaaga cctgttgctg gctttcaatc
     1921 cctgcttgag aaaactgtcc caccaattcc cgaatgcgtt ctgtcttgat gacctgattg
     1981 actggcttaa tcaaggtgac atctggaaac tcttcctgtt caatcagctt gcaacttcgg
     2041 catttctcac atggtaagac gccaacttta tccgtacaaa aaaggctctt agctaaaaat
     2101 tgcgccattt ccaagcttcc aaagaaacct gaaaagagat aggcgtgatt gagctggtct
     2161 tgttctaaga tacggacaaa acggtcaaac tgagctggtt gccaagcctt tagttgatct
     2221 tgtttcattt ggccaagccc attccgtcaa acaagacagc cttggtagtt tccacaactt
     2281 gctccaaagg gagactagca tcaatcttga caatgcgatt tccctcttta tccagaagag
     2341 aaaggtagcc ttgacgaact tttttatgca agtccaaccc ttccaaatcc aaacgattaa
     2401 cctcgcggtc actattagca gcaatacgag ccagcccttc ttccacctcg atgtcaaaat
     2461 agagtgtcaa atcgggtttg aggccatctg tcgcaaactg attgagccag tcaatggctt
     2521 caatatctaa gccacgacca aatccctgat aggcaacaga actatcgata aaacgatcca
     2581 tgatgaccaa cttgccagct tcaagggctg gaagaacttt ttccaccaaa tgctgtctgc
     2641 gactggcaat atagagcaaa agctctgtct tcgcatccat ctgagtatga cttggatcca
     2701 aaatcacttc ccgaatcttc tccccaatca agactccgcc aggttcacgg gtcgtcaaca
     2761 cctctactcc tttttcctct aaaattggta gcagagcctc taaaacactg gtcttgcctg
     2821 ctccctctgg tccctcaaga gagactaaaa atccttttga catgtctaac tcatttcttt
     2881 tttactactt ctattctatc aaaaaaatag gagtttgtga caatcttttt gtgtcttctc
     2941 atttcagcca ccataaaaga ggcagtcaaa gctacctctt atttacctag ttcttgtgtt
     3001 cgtttatagg cttgatgaac tgcctccatg actatgcctc gaaaagcatg cgcttctaag
     3061 cttgctacgc cagcaatagt cgaaccgcct ggactacaaa cttgatcttt caaaactcca
     3121 ggatgttgct ggctttctag gaccaattgc ccagctccta ccacagtttg ggctgccatt
     3181 ttcaaggctg tttctcgtgg taatcccgtc tgaacacctg catctgccaa agcctcaata
     3241 aagagataga caaaggctgg tccacagcct gcaagacctg tcgctgcatt gattaagctt
     3301 tctcctaatt caaccaagag accagccttg gataaaagct gacaaaagag ctcactgtcc
     3361 tcagccctgc aattaggaga caaggcataa ctaatcactc cttgcccgat agaagcaggg
     3421 gtattaggca tcatacgaat aattcggtgt tgacttggga taagacttgc tagtttttct
     3481 aaggtcaatc cagctgccat cgaaatcaaa agaagacttt ctcttttttc aaggatggtc
     3541 tggtattgag aaagcagttc agaaaactga gcaggcttaa ctcctagaaa aatcacatct
     3601 gcttctgcaa acatttcttc attgctggaa gcctgaccac caaagtctgc aatgaaagca
     3661 tctaccttag cttgactacg attggcaagg agaatctcat ctgacgtcct agtctgcaag
     3721 acagattttg ccaagctagc acccatattc cccaaaccga taaatccaat cttcatctct
     3781 tactccctta tctgcccatc accagcaacc acatacttgt agctggtcaa ctctttcaag
     3841 cccattggac cacgcgcgtg caatttctga gtagaaatcc ccatttcaca accaagacca
     3901 aattgtcctc catctgtgaa acgagttgag gcattaacat acaccgctgc agagtccact
     3961 tgatctgtaa agtatgctgc agcttcagca ttttccgtca caatagcatc cgaatgatgg
     4021 gtgctgtggg attcaatgtg cgcaaccgct tcttctaaac tgctcacaac cttaacagca
     4081 aggacatagt ctaaaaactc ggtgtcaaag tcttgggtct cagctgcttg acctgaaaca
     4141 aactggcttg ctttgctatc caagcggaat tgaattggtt ccagtccagc ttccttacgc
     4201 tctgcaacca gcatttgatc caagcgagga aggatgcttg ctgccttgtt ttcatgaacc
     4261 agcagaacct ccatggcatt acaaacagaa ggacgactgg ttttagcatt gttgatgata
     4321 gacagcgcct tgtcttcgtc tgcatcctta tccacataga catggacaat cccagtccct
     4381 gtctcgataa caggtacaat cgcattctca accactgcat tgatcaagcc agctcctcca
     4441 cgaggaatga gaaggtctag atagcccttg gccttcatca tagcataact actttcacgg
     4501 ctagtatcct ccaccagttg aatcacattt ggatgaatag tagtcgtctc caagcccttc
     4561 ttcaaggctg tgacaatggc atgggttgtt tgataggcat ccttaccact acgaagaaca
     4621 accgcatttc cactcttaag agtcaaagca gccgcatcag acgtcacatt tggacggctt
     4681 tcatagataa taccgatgac acccatagct acacgttttt ttgtgataac caaaccattt
     4741 tcaagctgac ttgtttctaa aacttcaccg attggatctg gtaaggcaac cacttcacga
     4801 attcctcttg ccatcgcttc tatacgatct gcatccaaat aaagacgatc caacatcaca
     4861 tctgagattt tccccttagc cgctgccata tcgagggcat tagccgctaa aatttcctca
     4921 gtagcagcca ctaagtgatc agccatggct agcaaggctt ggtttttcac ttcttcacta
     4981 gctgtgttaa tcgatttttt aacagcctgt acctgttcaa attgttcttg tctactcacc
     5041 atagtttacc tctaaaattc tgtaaaaagt agttggattt caggagtaat ggaaatccag
     5101 tcgtcacggt aaatcaagac acccttggct ttttgagaac gcaacatatc ctccaaagca
     5161 gatgctccaa attgcacgcg tccttttcca agtgattttc cactttcctt atcaaatact
     5221 gtcacgatat caccgtaaga aaagactcct tctgcttcaa cgataccaga taagagaaga
     5281 ctctttccat gttgagagag agcttccgca gcccctttat caacccaaat agaaccttga
     5341 ctctgagcat agaaggcaag ccattgtttc tgggtacgaa gccccttctc ttgagcaaca
     5401 aagtaagaac catcctcggt ctcctctgcc gcctcaatca tggaatctga tttcaaggat
     5461 gagcagatat aaacaggaac tcctgattcc gtcgcgatag ttgcagcctt gattttggtt
     5521 aacatacccc cagttccgtt tgacgaacca gctccaccag ccatatcaat aatctcacga
     5581 ttgatggtct cgattctctc caagcgtttg gctcttggat ctgaattagg atttccagta
     5641 tagagaccgt ccacatctgt caagaaaact aaaaggtctg cttggaccat cgccgctact
     5701 tgagcactta gagtgtcatt gtccccaacc ttgagctcat caataacgac actatcattc
     5761 tcattgatga taggaattgc cccacggttg agcaaaaccg acaaagcctg atgggcattt
     5821 ttataacgac gcttatccac aaagtcatct tgggtcagca agatttgtgc agaaacgatt
     5881 tgacgcaaga gaagattggt cgtatattct tccaacaaaa gtccctgccc taccgctgct
     5941 gaagcctgtt tatcagcaat tttagtcgga cgctttttaa atcctaaggc tccaaaacca
     6001 gccgcaatgg cacctgaaga caccaaaatc aactcatgac cagcctcgtg cagcatagcc
     6061 aactgctggg taatatcctt taccttacta cgtgataaac ttccatcctc atttgtcaga
     6121 gaagaagtac ccaccttaaa gacaatccgt ttgtatttca tagtctcact ccgattattc
     6181 atatttatcc attataacat gaataacagg aaatagaaaa gagttgatag gaaaaagaag
     6241 gccctaaaac cttcttttct actactgttc tgattccgat ttgtttacac tcgtttcaga
     6301 gctttgtgaa gttgaggatg tcaaatcttg actagttgaa aaatttgtaa cactttcatg
     6361 ttgactcgtt tctttatttt caagatcctt tttcactact tctttggatt cttttatttc
     6421 tgaatgactt gtagttttaa ttgtagcaga tttctcgatc gaaacatcca ctaaccaggc
     6481 accacttgaa tccacagtat aaccttctgg tgtcttaccg ttcacaagta attgaccatt
     6541 ttctttcaag aagtaccatt tatccttgtc cttgatccaa cccacagctc gtgaaccgtc
     6601 tgtcttgtag aaataccaat catttgcctt tttatgccag ccttgcttca tagctcctga
     6661 atcttccaga taataatgtt gaccagcaac ttctatctca cctgtcttca tgacaccagt
     6721 agaatccata tagtaccagg tttctttatc ttttacccag cccattttca tttcccctga
     6781 tggagcaaag taataccatt gccccatata ttgaagccat cctatcttca tagaaccatc
     6841 aacatccaaa taataccact gctctttatc ttgaacccaa ccaatttcca tctgattttc
     6901 tttgttaaaa taataccaga ttccatcaat tttcttccaa tttttagcag aagcaccaga
     6961 gtctgtcaaa tagaaccaat gattgttcca ttttttccat tgattctgta acaagatacc
     7021 cgtttggtta aagtaatacc attcaccttc gatttcattc caaccgacag catactctcc
     7081 tgtagaatca ggcgcttgat accaccagtt cccatatgca ctcttatgcc aaccagcttg
     7141 aaaacttgga atcggcttgt aggatgttga aatattgaca aaaccgtctt ttcgaatatc
     7201 aaaaactgtt gcatcatagt ctttgctggc tgcgttgatt ctctcaattc ctcgttcttt
     7261 gagccaatta acatactcac tatcaacacc atttttccaa ggtagactat ccgaagtttg
     7321 aacaatcaaa ctcggactca aatttttaat gaaatccttg gtatttgatt tgttggtatc
     7381 atggtgatga ttaaacttca tcaaatcaac ttttccaatg agaggaccat acttgtcttc
     7441 tgctccatga acattatcta aatcgccccc aaggtaaatt ttcttgccat tgactttcac
     7501 cacgctaatc aaggaattgg aattgtcatc ccaaattttc tttaattcac ccgatgaatc
     7561 agtttcattt tcataattat agagctgaat atccatgtcc ccaaactgaa aatgagcatc
     7621 cccttgtgtg atattttgaa taactgaaac acctttttct gcagcagtct gtaaaacctt
     7681 atcatagcca tacagattat cccatagacg ttcagaatta gtaatacgac tatcactata
     7741 tttcttaaga tagactcggt caactggata ggtagacagt aattcatcaa catttccaat
     7801 atgatcactg tgggtatggg tcaccaaaat aaaatcaagt ttttggacac tcaattcctt
     7861 caaacgacga aagacacggt ctgttagaac atgcttataa gacgtttcaa ttccttctct
     7921 ccatggataa cgagaatcac ttccatctgg gaaatcataa tcttctcctg tatccaccat
     7981 ggcaaaatgt ccattgcttt caagaataat cgcatcactg ccaccttctt gaacattgat
     8041 aaagtggatt ttatttcctg aactttcttg agcctgaaca ttcccatacc atgacaaacc
     8101 taaaaaagcg cctacaagtg ctaaactagt taatttcttt ttcattctta ctttctcaat
     8161 ctctccaagg tttccttaaa aatctctggg atatctgctt taaattccaa ggtcttacct
     8221 gttctcggat gagtaaaacc taaagtcttg gcatgaagaa attgtccatg tcctttcaaa
     8281 gtcttgcgag gaccatagac ctcatcacca gcgactggat ggccgatata agccatgtgg
     8341 acacggattt gatgagtgcg ccctgtctcc agttgcaact ctactaagct ataatcgcca
     8401 aagcgttcca agacgtgaaa acgcgtcact gcaggcttcc ctttagcagt tacagcctgt
     8461 ttcttacggt ctttttcact ccggccaatc ggcgcttcaa ttacaccacg atcattaggc
     8521 agatttccat gaacaatcgc ccaatatttg cggagagact ttttatcttt gagttcttgg
     8581 gcaagtacta gatgcgcatc atcgttttta gcaatcatga gaagacctga cgtatcctta
     8641 tcaatacggt gaacaatccc tggacgcaga accccattga tacccgacaa gtccttaata
     8701 tgatacatga gggcatttac tagggttcca ctggtatgac cagcactcgg gtgcacaacc
     8761 attccctgag gtttgttaac gacagccaca tcctcatctt ggtagactat ttctagcgga
     8821 agatcctcag ccacatactc taatacctct ggttctggca catggtaagt gacgacatca
     8881 ccctcttgga ctgtgtattt agctttcttg acttgaccat tgaccaagac ctggcctgat
     8941 ttaatttgtt cattcgcgag actacgtgat aattctgaca aatctgacaa agccttatcc
     9001 aaacgcagac caccagtttc aattttaatt tccatttatt tcctctttta gcattgcaat
     9061 caataaaata atcactccaa ccgtcagata gctatctgcc acattgaaaa ttgcaaagtt
     9121 gataaagtca aggtggaaca tatccacaac aaagccctga ctgaccctgt caataaagtt
     9181 tccaagacca cccgcgatta ttagagtcaa acccaagacc atccagaatg agtcctccat
     9241 gtgtttatgt aaataccaaa tggcacctat cacgacaacc agagtaatga cagcgaataa
     9301 cagctgctga tcttgtaaga tagaaaaggc tgcacctcga ttttgcaggt aggtcaagct
     9361 aacgaaattg ggaatccagg agcgcacttc acccagtgga atctgctgga cgatatagga
     9421 tttgaccaac tgatccagcc caattaaaag cagtacaatg actgccacta ttgctctttt
     9481 tttcatgatt tcctcttttg atcaaaatat tcttgcatga cttctacgaa gagagtccca
     9541 gcttgactaa gctccacttc ttcacgttta acatagacca tgcggttatc taggttatcc
     9601 ttgagacgaa taactgtaat gccattaaca ctgtcactat ctaaaaatcc agaacctgtc
     9661 gcataggcgt ccgtccgctc caaaatacca ttcaaggtgg cacggtctgt cacattaaac
     9721 atctgtgagc tagcgctggt atcgacaaag ttctctgaat aataaaggta ctcgtctttc
     9781 tcttgagtga aacgaaccgt tggtaaatcc gctaaatcct ccatgactaa ttcctctttc
     9841 tgggctaaag gatgaccctc acagagataa atatgggtat ggaaaggaat caattcgatg
     9901 acctccagac ctaacttttc aacccgttgc ataatcccct ttttattttg attgttgagg
     9961 tagataatcc caatctcact atgcccttgc gccacttcat ctaatatttg aacagtagtt
    10021 gattcaaaaa tacggaagtt cttatagtca ggatagcgct ctgaaaaggc cgtaatagtt
    10081 ggtggtaaga agtcatagtg ctggctagca acggaaaatt catctttttc ttcttcagga
    10141 ttggcatact gattttgaaa aatatcaaat cctttaacca attcttgcga tttttcatag
    10201 aattccatcc cacgacgggt caagaaagtc cctgagctgg tccgacggaa aatcttaaaa
    10261 cccaactctt tttccaaatc acgaacagaa atagacagac tcggctgact aacatacatc
    10321 ttttcagcag cttcacggaa agtaccacta ttggcaatgg caacaacata gcgtaattgt
    10381 tgaatgttca tcttctaccc ccaacttctt tatcttttca ttataccata ttttagaagt
    10441 tttccaaaaa ggaaaaaaga acatcctatt cttcttaact atcttcacta tctgcctttc
    10501 tcaagccaac cttattttca aaatcaattc aaaaaaataa gtggctacac accacttcag
    10561 tatcggaaag aaaaacgttg actatttgtg aaaaaagaaa atgccggaaa gttccgacat
    10621 tgttttagta agctaacttc ctgaaaatag gagtaaccat acattccaga aggcagtgat
    10681 attgatgaga atatgtacta gtattggata gtagagactt ttggtcatgc gatacaatag
    10741 agccaaaata aggcctccac tagcataaat gaaaaaagca agaggagtta aagcaaaatt
    10801 gatatgaata taaccgaaaa taatagcaga aagcaagaca tctccgtacc aaggcgagtt
    10861 tttgaaaaag gttgtcataa gcacaccgcg ataaatcaat tcctcagcaa taggggcgat
    10921 gaagcaaacg atgagcaaga aataagggaa ctcctgtcgt cccatcattt ctatcgtttc
    10981 attcaaagaa atttgatttg aaggcgggga tatgaaatac gaaaagagaa agtcagacat
    11041 atacgaaatg atgtagccca gtaaaaggta gataaagtac ctcagctgcc acttgaaatg
    11101 aaaaatcttc tttcctgcaa aaaccagtag atagatgacc gctaagaaaa gaactccgct
    11161 ctccatcaaa agcagaatct gaaaaaattc acgacttgct ggtagatagg gctttgcgag
    11221 gtgattgaaa actctccaaa accaagttga tttgtaaaaa attaaggaca atgctagtaa
    11281 aatttgaata gcccgttttt tcatattaaa ttctctgctt tctccacttg tttcttcata
    11341 ttcctaataa attttactta aaatctcgca gcacttcctt tgcaaagatg attgcctcct
    11401 ccaatatatc ctaaatcata ggtgcctctg ggacaaaatc catgaaccgg cagagttaat
    11461 actggttcta tttcccaatc gtacctacca ttaggatttt taccataggg atctgctcca
    11521 ccttgtatca gctctaattc ttcatttgtt agatttatat tttttgtcat taaaatcatg
    11581 atatatttcc tccattattc ttcagattag ttgagtaatc tactactcat acctacttac
    11641 aaaaaaacta ttttaagcta gtttttttat gcttgtctag ttgcaacgtt gacaagttta
    11701 gtatagcata tctttgccaa atatcctctt caaatcttga attgtcatcg aaacgtccta
    11761 aactgcaaaa tcaattagtc tcaagctttc tatcaatttc ttctccaaaa tatgctataa
    11821 taatagcaaa agataaagaa ggaagaccta tgattaaact actagccttg gatatggacg
    11881 gcaccctcct caatgaagtc aaggaaatcc cacaagctca cattactgct attcacaaag
    11941 ccattgaaaa aggtgtcaaa ctggttctct gtacgggtcg cccccttttc ggtgtcctcc
    12001 cctactacaa aaaactggga ctcgacctcc agaatgagta tgtgattgtt aacaacggtt
    12061 gttcaactca ccagactagc gactggggct tggttgactg gcaagaactg agtccagctg
    12121 acatcgaata cctctatgac cttgctgaaa agagtgatgt tcagttgaca ctttttgacg
    12181 agtcacatta ttttgttctc ggtggcaagc ccaatcaagt tattgaaaat gatgctaaac
    12241 tagtattttc agacctgact gaaatttctc ttgaagaagc gactagtgga aagttccgga
    12301 tgttccaagg tatgttttta ggaacaaaag aacaaacaga cgattttgag cagcgttttg
    12361 ctgaagagct ttgccaacga ttcagtggag ttcgttcgca gcctgtcatt tatgaagcaa
    12421 tgccgcttgg aacgacaaag gctactgctc tttcacgact agctgagatt ttgaagattg
    12481 attcctcaga gattatggcc atgggcgatg ctaataacga tatcgaaatg ctccagtttg
    12541 cagggcttgg gattgcaatg ggaactgcca gcgattatgt caaatctctt gcggatgccg
    12601 ttacctcaag caacgaagaa gacggcgttg cgcgtgctat tgagaaatat attctataaa
    12661 aaagaaaagc aaatagacag aagttactgc tatttgcttt tttgctaata ttttaaaata
    12721 cggactaatc aatagacaag aatagcgaat cataaaaatc gatttactag atgccatagt
    12781 atcttatagt tgctaataag aagttagtct agtagaatga atctctcatt tctcccacac
    12841 taatctgtaa tttgtctata catttctggt cttctatctc gaaacaagcc ccagtttaga
    12901 cgttcacttg ctcccttgtc taggtcataa gtagctaaca gaacagcttc ttcttgtctt
    12961 tcagctcgtt ctagaatagc tcctgtttca tccgtcataa aggaggaacc gtagaagtca
    13021 agactggaac tctgtccgcc attttcctca ctaggagtaa cctcctctaa accataacga
    13081 ttggctgcga tgactggaac aatattcgct gctgcgtgcc cttgcatagt acgttgccag
    13141 tgaccacaac tatctgtatc caaaattggc tctgaaccga tagctgtagg ataaaagagc
    13201 aattcagcac cattcaatgc aagacagcgc gctgtttcag ggaaccattg atcccaacag
    13261 ataccgatac caatcttggc atagcgagta ttccagacct tgaaaccagt gttaccaggc
    13321 gtgaaataga atttttcttg ataataatgg tcatctggta tgtgggtctt tcgataaacg
    13381 cccagcactt ccccatctgc atcaatgacg gcaatagagt tatacaagac attaccatct
    13441 ttttcataga aactgattgg taaaacaact tgtagttcct tagcaatcac cttaaaatgc
    13501 tgaatggcag tattttccgc tacagattgg gcatactggt agtagtcata ctgacgttcc
    13561 tgacagaaat agggatgttc aaacaactcg ggcaagagaa taatttgggc tccttgctca
    13621 gcagcctgac gtactaaacg ctctgcggtt tggatatttg ttgccacatc cttagcgcat
    13681 tgcatctgaa tggttgcaac tcttacattt ctcatctttt tctcctattc tggaatttgt
    13741 tgggtgatac agtggatatt gccaccacct aagagaatat ctctggctgg tattccgaca
    13801 actttacggt ctgggaaaca cttgctgagg atatctaagg ccacttggtc gtttacatcc
    13861 tcaaactgtg gaaccaagac agccttgttg gcgatataaa agtttacgta ggaagctgct
    13921 agtcgttcac ctgcgtatcg ctcttcttct ccttcttcat agatgtagcc tggcaaatct
    13981 tcttctgtca caacttgtcg aactgcaggg ataggcaatt tatgaatggt gaagtgacaa
    14041 ccttttgcat ctgtttcctg ttctaagagt tcgagatctg cttttgacat ggcatactgg
    14101 ggatcatttt cgtcatctgt ccaagccaaa acaagctcag caggaccaac aaaggcagca
    14161 acattatcga cgtgttcatt ggtttcatcc tgataaatac cataaggaag ccaaataact
    14221 ttttcagcac caagactttc taataatgtg ttttcaatct cctctttagt caagttagga
    14281 ttgcgaccag gactaagcaa gcaactttca gttacgagaa tagttccttg accatcgcta
    14341 tggattgcgc ctccttccag tacaaaaggt ttagcatcat agacaggcct ttccaaggcc
    14401 tcagcaaaac gactggctac ttggtcatcc tcttcataat cttgataaag accatcatag
    14461 gtgcctcccc aagcattgaa ggcccaatcc acggctaatt tcttaccttt atcattgacg
    14521 agaatggttg ggccagtatc acgcgcccag gcatcattgg tgggaatgtc taaataaaca
    14581 accttgtctc caagatagga ttgggcttca gatagatagg cctgctccac caaaagatag
    14641 actctttccc cttctgctat ggtctcgatg atctgagtaa atgctctttt agcagccttt
    14701 ccttgaaaag gccatgatcc tggtcgagtc ggccatatca tgagggtacc atgatggggt
    14761 tcgtactctg ctggcatgtg atagcctaat ttttttggac tgtccatcat gataatctcc
    14821 ctttaaagtc ttgatagcca aaagctttga gtaagctaca gtctccctgt tcgtccatga
    14881 gatagagact tggcaatcca ataccattaa aggtattatt tttgacaaaa gaataaatgg
    14941 ccatgtcttg aaaataaagt ctgtctccga tttggactgg attttcaaaa ctataatcac
    15001 caatcacatc gccagtcaga caggtattag aagaaagtct gtaggtatgg gctttttcct
    15061 gtgcctcaaa gccatttctc aaaggtggac gatagggcat ctcaagtaca tcaggcatat
    15121 ggcaggtcgc agaggcgtct aaaaccaaga tttccatacc gttttctaca atatctaata
    15181 cctcagttgc taaataaccc gcattaagcg caatggcttc accaggctcg atatatattt
    15241 caagattgta agtttttcgg atacgcttga tttctgaaat cagcaaatcc acatcgtaac
    15301 cttctcttgt aatatgatga ccaccaccca tattgagcca ttttacctca tgtaagtagg
    15361 gaccaaactg ttcttctact gctttcaaag ttgtttgtaa atcatctgct ccctgctcgc
    15421 aaagggtatg aaaatgaagt ccgtcaacca aatctagcaa atcactcgga atcttgtcta
    15481 tagtaactcc aaagcgagaa cctggtgcac aagggtcata gagcgcgtga tctccttgag
    15541 ttgaacactg agggttgagg cgcaaaccaa cactgacacc agcctctcga caacgagccc
    15601 catgcttacg caactgtctc tctgagttaa agacgatatg gtctgttatc ccaagcaatt
    15661 cctccaagtc tgcatccttg aaagcaggcg caaatacatg gacttcacca ggaaattctt
    15721 cccttgccaa tttggcctca tagagtccac tagctgtcgt acctgataga tactggctaa
    15781 tcaagggata agttttgtag agggaatatg ccttctgggc aagcaagacc ttgcaaccga
    15841 cctcttcttg tacatattgt agaatgcggc aattagcttc taacttggcc aagtcaataa
    15901 cataggctgg tgttggtact tgttctaact tcattagtcc accatttgtg gattttcaac
    15961 cacaacccat ggcaaaccat actcattcaa agcttccatg aatggatctg gatctaactc
    16021 ctcaaggtta tacactccag cttgtttcca agttccgttc atgactaatt ttgtcccaat
    16081 catggctgga acgcctgtcg tgtatgaaat tgcttgtgac ccgacttctg catagcactc
    16141 ttgatggtcg caaacattgt agatgtagat agtcttttca acgccatctt tgacacctgt
    16201 aaagatacat ccaatattgg ttttacctac agtacgtggg ccaaggctag caggatctgg
    16261 aagcaaggct ttcaaaaatt gaattggaac aatttcttgg ccgttaaagt taatggtatc
    16321 cgtacgaagg agtccaacat tttcaagaca tttcatgtgc gtcaagtaag attgaccaaa
    16381 agtcataaag aaacgaatgc gtttgacacc tggaatgttc ttggccaatg attcgatttc
    16441 ttcatggtga aggagataca tatctttttg tccaacttga gggaaatcat actcacgctt
    16501 gatagacata gcttcgactt cgacccattt cccatcttcc cagtaagaac ctggcgcaga
    16561 aacctcacgg agattaattt ctggattaaa gttggttgca aatggataac cgtggtcacc
    16621 gccattacag tctaaaatgt cgatataatg gatttcatca aaatagtgtt tgagggcata
    16681 agctgaaaag acactagtta cacctgggtc aaaaccagaa ccaagaagag cagtcaagcc
    16741 tgcttctttg aatttctctt gataaaccca ctgccatgag tagtcaaagt aggctgtaaa
    16801 accaagttcc ttacaacgtt tttcgtaaat agcacgccac tcagggtctt ctgtgtcttc
    16861 tgcttcgtag ttggctgtat cgatatagtg aacacctgtt gccaaacaag catccataat
    16921 ggttaaatct tgataaggca gagctacatt caaaacagct tctggtttgt agctttcaat
    16981 caaggtaatg acctcttcta ccttgtcagc atcaagtgct gcagtttcaa ttttagtact
    17041 tgttttgcct tctagcttcg ctttcaagtc atcgcatttt gacttggtac ggctagcaat
    17101 cataatctct gtaaatgttt cgctatcttg acaaattttt gaaatagcaa cttgggcaac
    17161 gcccccacaa ccaataacta gtaaacgact catttttttc cttcctcttc ttctaaaatg
    17221 tcctcaacat acttgggcaa cataaaggct cccacgtgta agtttgcagt gtagtattct
    17281 gtgaaaagct ggcgtttttt ccaaccttcc ttgtcaaaat ctttgacagg gtggtatttt
    17341 ttcgatgcaa atccaaacaa ccaatagcca gctgggctag ttggaatatg ggcctgataa
    17401 acccgactga ttggaaagga ttgattgacc ttgcggtgca tgcttcggca ggccgactca
    17461 tcctcgtcaa agaagggact cccatgctgg taaatcatga tgccgtcttc cttcagagct
    17521 cgataactat tgccgtagaa ttccttggta aagagtcctt ccgtatggcc aaatggatct
    17581 gtcgcatcgt tgatgataat atcgtaatca tcttcgcagt ttcgcaaaaa gcgtagccca
    17641 ttttggtagt aaatggtaac acgaggatca tctagccctg cagcaaagtc tgggaaatac
    17701 tcacgacaga cctcgaccaa catctcatcc ggttccacga tatcgatttg ttccagttca
    17761 ggatagagtg ttaatacttg ggcaacaccg ccgtcacccc ccccaataac caatactttc
    17821 tttggatttg ggtggacagc catgggaacg tgaacggtca tttcattgta gacgaaatca
    17881 tccgcatctg agaacaagac atggccattt aaaatcagta ttttcccaaa agctggcgta
    17941 tccaagactt cgatatcctg ccattcactt tttccagcgt aaagttgctt ggctgttctc
    18001 agagacaatt tgacatctgg agtatgaact tcagaaaacc ataaatccat ctatttctcc
    18061 ttatattata tttagcgcag ttagctactg ccaaagccca agtggtatac ttggaataag
    18121 ccactgtgga ttagttcatt tcctccaatc gcttgacgat ttccgaaagg ctctaaccac
    18181 agcttttgtt tcaattggta atgagtttga taacgcatag acgttttatc tcgtctaagg
    18241 taacaaggca aaaagttcgt ggataaccaa gtagacttga aatactacat ctggaggtac
    18301 tcccatgctt tatgtgggca ttgatatcgc taaaaataaa cacgatgtta cagccttgaa
    18361 tgttcaagga aaaactgttc ttaaaccact cactttttca aataataaag ctggttttga
    18421 actcttagat ctgtctcttc gacagctcaa ccaagactgt ctcatcgctc ttgaagatac
    18481 tggacattat gcctttaatc tactgaactt cctgcatgaa caaggatata aagtttacac
    18541 ctacaatcct ttgctcatca agaaatttgc caaatcatta tcacttcgca agactaaaac
    18601 ggataagaaa gacgctcatg gcatcgctct taaacttctt tctgacccca atcgtgaaca
    18661 atttcaacac aataatcggc aagtagaact aaaaatactg actagacata ttcatcgtct
    18721 caagaaaaaa cagtctgatt ggaaagtaca atacactcgt tgtcttgata tcatctttcc
    18781 tgagttggat aaaatcgttg gaaagcattc agaatatacc taccaactct tgacacgcta
    18841 ccctaatcct cagaaaagga ttgaggcagg atttgataag ctgatagaaa ttaagcgatt
    18901 gaccgcttct aattcaaggg ctttttgccg tgctctaaaa tcatcgccaa atcatcaaat
    18961 tgaaataaga aatagtttag ataaaactat tgacttttct tatagtttgt ctttctctta
    19021 ataacgttga tatgattgac ctctggatct tccgtccctt ggagggagca accacgttcc
    19081 ttggcgaatt ggatatagtc gacaatttct cgtgtaatgc gttcaccagg agccaagata
    19141 ggaatacctg gagggtaaca cataacaaat tctccacaga cctgtccaac agaatcatcc
    19201 aaagttaaac tttttctttc tgaatagaag gcttcttgcg gagacagcac taactcgggc
    19261 tgaatatatt ctcctgctat caaatctttt ccatctcttg aatagagtct cttaatatca
    19321 gccagagcac caaccaagcg ctcgatgtct tggatgcggt cgccgatgga aatataggcc
    19381 aagatattgc cgatatcacc aaactcgatc tgaatgtcgt attcgtctcg caagaggtca
    19441 taaacctcga tacctgttaa gccaataccc tgagtgtaaa ctgacaactt agttacgtca
    19501 aaatcgcaaa ccgaaacacc gtctattaac tcttttgagt aggcatagta gccaccgata
    19561 gcattgattt cacggcgggc atactcagat agctcaatga ctttctcaaa cgactcttta
    19621 ccacgaaggg ccaagttgcg acgtgaaata tccaaactag ccatcaacaa gtaagaggca
    19681 gatgtagact gggtcaggtt aattatctga cgaacgtatt cagaattcat ctgctccccg
    19741 ataagtaaaa tggagctttg ggtcaaactc ccaccagact tatgcatgga aactgctgcc
    19801 atatcagccc ctgcatccat agcagaaatt ggaagtttat cagtgaaatg caaatgcgct
    19861 ccgtgggctt catctactaa aaccatcatg ccagcttcat gagccatttc tgtcaacccc
    19921 tttaggtctg aacagatgcc gtagtaagta ggattgttga ttaggatagc cttagcatct
    19981 ggatggtcct ttatggcctg tgctactcgg tcattttcaa gacctaaagc gataccaatc
    20041 ttaggatcta cactcatctc gatatagatg ggaatggcac cacatagaac caacgcattg
    20101 atagcagatt tatggacatt tcgtggcaga ataatcttat ctcctgcctt gcaggttgcc
    20161 agaatcatag tctgcaccga tgaagttgtt ccaccaatca ttagaaaggc atggctagct
    20221 ccaaaagcat ctgcagccag ctcctctgca tcacgaataa tcgaaatagg atggcctaaa
    20281 ttatccaagg gtttcatcga attgacatca atgcctacac atttttctcc taagagttcg
    20341 acaagttctg gatttccccg tccacgcttg tgacctggaa catcaaaggg aacaatcctt
    20401 ttcttgcgta acttcaccaa ggcctcataa attggggctt ggttttgatc taactctttc
    20461 aaaacatact cctttcaata tttttaggac cttatgaaaa ctaaggaact aaaggttgac
    20521 tcatgaaaaa agagcaggtt ttcacctgct ctgcaatctt ctgacgtgtt tattttggtt
    20581 tctgttgagt atgtctgttc ccgatgtttc ctaactctct agtagcaaat attacgtact
    20641 ttattgatcg tttcacaaga tgacgtgtgc tttcaccaca ctaaaaattt atgaattagg
    20701 acaagtgtcc taacatcaac ttataaaagt aggcttttaa ccctatcaat aatgtggctt
    20761 ttcaaccacg cttcggcatt caaccctacc tgtccgtagg cattttttac tcgggtttat
    20821 atttgctaga aaacatcatc tcattttcta agctttatta ctatatcatg tttttaagaa
    20881 cttgtaaagt attttttgat aaaaaacaaa aatatagtag attgaaacta
//
LOCUS       DAVLUM010000038        20662 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLUM010000038 DAVLUM010000000
VERSION     DAVLUM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.038"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(370..1977)
                     /locus_tag="VYN42_001251"
     CDS             complement(370..1977)
                     /locus_tag="VYN42_001251"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1462321.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2367..2954)
                     /locus_tag="VYN42_001252"
     CDS             complement(2367..2954)
                     /locus_tag="VYN42_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1462322.1"
                     /translation="MKLEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVTPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3082..3531)
                     /locus_tag="VYN42_001253"
     CDS             complement(3082..3531)
                     /locus_tag="VYN42_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEV1462323.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            complement(3536..3925)
                     /locus_tag="VYN42_001254"
     CDS             complement(3536..3925)
                     /locus_tag="VYN42_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1462324.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3953..4579)
                     /locus_tag="VYN42_001255"
     CDS             complement(3953..4579)
                     /locus_tag="VYN42_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1462325.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4593..5156)
                     /locus_tag="VYN42_001256"
     CDS             complement(4593..5156)
                     /locus_tag="VYN42_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1462326.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5321..5555)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5609..6112)
                     /locus_tag="VYN42_001257"
     CDS             complement(5609..6112)
                     /locus_tag="VYN42_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1462327.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6305..7135)
                     /locus_tag="VYN42_001258"
     CDS             complement(6305..7135)
                     /locus_tag="VYN42_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1462328.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7120..8802)
                     /locus_tag="VYN42_001259"
     CDS             complement(7120..8802)
                     /locus_tag="VYN42_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462329.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQAAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8904..9161)
                     /locus_tag="VYN42_001260"
     CDS             complement(8904..9161)
                     /locus_tag="VYN42_001260"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462330.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9168..9716)
                     /locus_tag="VYN42_001261"
     CDS             complement(9168..9716)
                     /locus_tag="VYN42_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1462331.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9731..10579)
                     /locus_tag="VYN42_001262"
     CDS             complement(9731..10579)
                     /locus_tag="VYN42_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1462332.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10768..12117
                     /gene="trkA"
                     /locus_tag="VYN42_001263"
     CDS             10768..12117
                     /gene="trkA"
                     /locus_tag="VYN42_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1462333.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVRDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12121..13560
                     /locus_tag="VYN42_001264"
     CDS             12121..13560
                     /locus_tag="VYN42_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1462334.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGNLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13688..15367)
                     /locus_tag="VYN42_001265"
     CDS             complement(13688..15367)
                     /locus_tag="VYN42_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1462335.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLILVVDILIYLPFCRAYDRQLLVKEDIASSNGIILEEDTSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGANLTEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKSLQFVLEHYQAV"
     gene            complement(15436..16848)
                     /gene="lacG"
                     /locus_tag="VYN42_001266"
     CDS             complement(15436..16848)
                     /gene="lacG"
                     /locus_tag="VYN42_001266"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1462336.1"
                     /translation="MENLQIKALLKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGAPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(16858..17202)
                     /locus_tag="VYN42_001267"
     CDS             complement(16858..17202)
                     /locus_tag="VYN42_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1462337.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(17380..19266)
                     /locus_tag="VYN42_001268"
     CDS             complement(17380..19266)
                     /locus_tag="VYN42_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV1462338.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYMRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFFALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIVEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(19268..20590)
                     /locus_tag="VYN42_001269"
     CDS             complement(19268..20590)
                     /locus_tag="VYN42_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1462339.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
BASE COUNT         6398 a         4607 c         3530 g         6127 t
ORIGIN      
        1 attttactat agtggattaa attaaaaaag tataatgtat tgaatctata acagtacatc
       61 ttgactgcta aaatatttct ataaattaat ttgacttttc tgatagagat gttcacatct
      121 tatttcaatt cactatacaa tccagttcct aaaactttgc tagaaattga tttggctttc
      181 cgaattaatt tgttcaaatt ttatttcatt tcaatatact gataaatcca ttcactagca
      241 cagggcaaga gggagtcgct attgatttca acggtagcag gtacatacag aggaccccta
      301 cctcagatat actgcaatat catcgtatgc aaaaaacctc tgagattttt ctcaaaggtt
      361 ctgattttgc taattgctgt tctcaaccgc tgcagtaaca aaggcagtgt agagttcttc
      421 tggtcggttt ggacggcttg acagttcagg gtgatactga caagctacaa agaatttatt
      481 ttcaggaatt tccacgattt ctaccaaacg attgtctgga gaaactcctg aaaagacaaa
      541 acctgctgcc tcaaactgct cacggaaggc attattaaac tcataacggt gacggtgacg
      601 gcgttgcacc acttcttgat tgtgataagc agcagcagcc ttagagccac gtttcaactt
      661 agacggataa agtcccaaac gaagggttcc acccatatcc tcaatatcaa tctgatcacg
      721 catgatatca atgatagggt attttgtttc tggtgcaagc tctgcagaat tggcaccttc
      781 aagacctaaa acgtgacgag caaactcgat acatgtcaac tgcattccca agcagactcc
      841 caacattgga acatcatttt cacgcgcata gcggatggct tggattttcc cttctgtacc
      901 acgttgacca aaaccacctg gtacgatgat cccgtccgca tcagacaaga gttctgctac
      961 attctctgct gtcacatcat tggcattgac ccaattgatt ttgacttcta catcattgac
     1021 atagccagag tgtttcaagg cttcgaccac tgagatatag gcatcttgca actccacata
     1081 cttaccaaca agggaaatct taacttgttt cttgaggttc atgaccttgt ccaccatggc
     1141 tgaccattct gtcatatccg ctgctggtgc gtctaatttc aaatgatcac aaacaatttg
     1201 gtccatccct tgtgcctgca agttcagtgg aatttggtaa aggtgttcaa catccaacga
     1261 ttcgataacg gcttctggtg ccacatcaca gaactgggcc agtttatttt taattccttg
     1321 accagctggc tcttctgtac gaataaccaa catatttggt tggattccca agccacgcaa
     1381 ttctttgaca gagtgttggg ttggtttggt tttcatttca ccagcagcct tgaggtaagg
     1441 aagcaaggtt gtatggatat acatgacatt atccgcaccc acatctgcct tcatctgacg
     1501 aagagcctct aggaatggca aggactcgat atctcctact gttccaccaa cctctgtgat
     1561 aatgacatca gagtcggtcg ttagagcggc acgcttgatt ttttctttca aagcatctgt
     1621 gatatgagga atgacttgaa cagttgcccc aaggtattct ccacggcgtt ctttacgaag
     1681 aacttcactg taaattttcc cagttgtcac gttggaatat ttgttgagat tgatatcgat
     1741 gaaacgttca tagtgaccca agtccaaatc tgtctcagct ccgtcatctg tcacaaaaac
     1801 ttccccgtgc tggtaaggac tcatggttcc cggatcaata ttgatataag ggtcaaactt
     1861 ttgaatggtt actttgagac cacgattttt caagagacgg cctagactcg ctgccacaat
     1921 ccctttccca atggacgata ccacaccacc agttacaaaa atatatttcg tagacataga
     1981 ttcctctttc taaaatgctc aaggtcttgt taactacgag gggatataga aaacaagacc
     2041 ctactaataa gaataatctg ggacgactgc accagattca caactaatac tcttcgaaaa
     2101 tctcttcaaa ccgcgtcaac gtcgccttgc cgtagatatg tgttcctgac tttgtcagtc
     2161 ttatctacaa cctcaaaaca gtgttttgag cagcctacgg ctagtttcct agcttgctct
     2221 ttgattttca ttgagtataa aatacaagaa gataacttct tgaaaaaaca aaaatagctc
     2281 cctaagaact agggagcccc gacctctaaa agaggtgccc aaacaatatg atacctaaaa
     2341 ataggataat tgtcaatagc taactcttat tcctcgctgg tttcagcgtc gtcgtctgaa
     2401 aactcgtcgt cgtcttcgtt gagatccaca tcttctccca agtcatctgg agcgatttcg
     2461 ttgatttctg catcataagc ttccacttca tttttttcat catctggatt ttcatcatcg
     2521 tatgaaagag ctggatctgc ttcgtatgca tcttcgtctt ctggatcatc tgcattgtag
     2581 tcaatggcat ctgaatcacc atccataaag gcattgacac gttttttctt agcttttggt
     2641 gttacttcat cgtcgtcatt ttcttcaaga gcgatgattt cttcgtcgat ttcgtccaca
     2701 ccataccatg aacgaagacc ccatttgttg tccccaagtg agatgaaact accgtcaaag
     2761 ttcaactctg tgtagaacaa aggcaaagct tcgcggatat cgctgtttga tgttccaagg
     2821 tagttttgaa tttcgtttac aagatcgcta aaatgcatct catgatcgcg accacgaagt
     2881 tccaagatag cacgcgctac ctcaatcata gatagttcac ttttttcttg cccagcaaat
     2941 acttctaatt tcaaagcgtt tctcctcatt tatactacta tcgccagagc gaacagactc
     3001 tgacctcatt ttatcattca ctctttattt tacgataatt ttgcggaata gtcaaaggtt
     3061 aagggggaga aagtggcagg attagactaa ttccaatata aaactcattc ctttttctgt
     3121 tgctccattt tccacaaatc caagcgactt gaaacacctc ctagaagcat gattgtaggt
     3181 gtagattttc ttgactctca attctttcca tccttttact cgagccaatt caatcaaagc
     3241 acttagaatc ttttttccaa gtcctcgatg ttggtaagcg gaattcccaa tcacaatggg
     3301 gagattatcc tgagatagtg taatatcccc aattggaaac cattctccct tctccttgac
     3361 ttcaatccaa aaaagctcac catgccgatc caaataggaa tacatggctt ccaaggtcgc
     3421 ttgactgtaa ggaagcttca ccccatctac gaggtaaacc aagttcacat cctgatacca
     3481 agcaaaagct tcctcacaat gattgacctt ataataagga acaaaacaca atgcactacc
     3541 ttttcaacaa aagagttgct gcttgattaa aaccatcaca ccagttatac cattttgctt
     3601 catacccatc ttgagctagg atacgatctt ctaaatcaaa aacagagtaa atctttcttt
     3661 cctcgcaagc ttgcgcatag agatgatata gttcatcacc accatctcta tcccactcag
     3721 cagaaatcgt atcccgacct gccaataaag cctgataagc cctgtgatgc ccatctgtaa
     3781 tcagcaaaca atctccaaag gcaagaatac tgattggatc gacttggatt gtttctgccg
     3841 actggtaaag catctgaata tcttgcaact tcttttctga taaatatagt tgagtcagat
     3901 gaagatctgc tatattgact ttcatttctt tctcctcaag ggaattcgat actcacttct
     3961 gtttgccttt aaatcgccat tggaagcgga gcttgtcata aaagggaaac tcgataaaca
     4021 ggactcccaa gcccacacag agactggcaa ggacgtctga tgggtaatga actcccagat
     4081 agactcttga taccagcaca ctgactaggt agaggccaag gacgatttgt acgatttttc
     4141 tccagacctg atctttaatc cgctgactaa gaataacaat caaagtccct accatcagcg
     4201 ttacagctag agaatgccca cttgggaagg aaaatccctt ctcctccacc agatgtaaaa
     4261 tagctggtcg tgggcgctgg tagatatttt taaaggtcac gattaaaaga cctgccaaag
     4321 ccagatttcc cagcatgaag aaactttcta tcttccatcg cttacgataa aagacaaaag
     4381 ctgtaataac aacccaagtg ataatcactg ggatatcaat cagacgtgtg agggctcgaa
     4441 aaagaatagt caaataatct ggtaagtctc ctcgaatggc agtctgaatc gattggtcaa
     4501 aattgaccaa catttcaggg taaaatttga ccatatagcc aagaataacg aaaagtaaaa
     4561 gggcaaaact gcccttcatt aaaaatgttt gtttatcttt catagtgttt taaggttggt
     4621 ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga ttacaccctc aatcaagtta
     4681 aaaggtaata ccatggtcat taggtagttg gaaagtccca aaatttttcc aatatcaaag
     4741 ttagcaaact tagcgtacaa aggaacagca taaacatagt tgagaaccaa catggccaag
     4801 gttaaaccaa cagttccagc tagagagcct agtaggaaac gaagggttgt ccgttccttt
     4861 ttccaaatca aagcaaatac gatgacaaaa actcccaaag ctacgatatt catcggcaaa
     4921 ccaatgtaag tattcactcc ttggctgtta agaagcaatt tcaatagtga gcgaagcaag
     4981 agcactccta gagcagcagg caaatccatg accaccagac caacaaggac tggcaagata
     5041 ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg gaaagtcaaa gtacatcagc
     5101 acaaatgaga tggctgatag aattgcaatg gtcgaaagtc gacgtgtgtt tgtcataaca
     5161 ggttcctcca attttctata aaatcagaag aagttggaaa ggattcctct atctattctc
     5221 actttttata tcccaaaagt tccctcttac tctattaaag aaaaacaaag caagtggtta
     5281 caatccggct ataaatctat caaaacagac aaagctattc tttcgtcttc tcccatccag
     5341 actatactgt cggttgtgga atctcaccac atcagcttgc gctcgcggac ttctttaaag
     5401 agaaggaaat agagattttt cttttagact aggcgacaag ctgtaggcat aacttctggt
     5461 taggcaaagc ttgtcaacaa agtataaaag gaaaagatca tttcctagtt aaagtcaccg
     5521 ccggtcggga atcacaccct gccctgaaga ctcttttatc ataacaaaaa acgcttgcaa
     5581 gcgcaagcat tttgttcatt ttcatttttt atttcaattt atccacttca taggtatgga
     5641 cgagttcaag acctgcaaag ttctgctggc gaagagcctc atagacaatc atgcagacgg
     5701 tattagacac attgagactg cggacatgtt catcattcat gggaatacga agagccttct
     5761 caggatgttc tcgcataaaa tcttcaggta agcccttgtc ttcacgtcca aagagaaaat
     5821 aatggtcctc gtcagtcgat aaatccacct cagaatagat tttttccgcg aatttcgaaa
     5881 tcagatagag ttttcccttc atctgagaca tgaaatcttc taagctctcg taaaaataaa
     5941 tctctagctt atcccagtaa tccaatccag cccgcttcat cttgcggtca tcaataggaa
     6001 agcccatagg cttgatgatg tggaggggag aattggtcgc agcgcaagta cgcgcgatat
     6061 tgcctgtatt ttgtggaatt tgaggttcaa ataatacaat gtgatttgtc atgacttgct
     6121 tcctttcacc attgcaaaaa aatagccaca ctgcccggag tcaagctcag caaacagcgt
     6181 ggttaaggca tcgttaactt acctcacaac aggtttgaag taaatcagcg aaactacttt
     6241 cttagtataa cactttcaga atcattgtca atagaaatga cttgattttt tcaatttttt
     6301 caagctattt ccaagggttg taaaatcgtc cctgattctg caagataagt agtaaactaa
     6361 ctactaaaaa caaggttgcc aagagcaagg taatatagtc tccttttttc aaggcctgat
     6421 aactatacca tgtgcgtttt ttctctttcc caaagcggcg aagctccatg gcagtcgcaa
     6481 tggtatcaat gcgttctagc gagctaaaaa tcaagggcgt aataatgagc agattgcctt
     6541 tgattcgttg cataagagaa gctttcttgg ataattccat cccacgcgcc tcctgagaca
     6601 tcttgatagt aaagaattct tcctgcaaat ctggaatata gcgcaaggtc aggctgacag
     6661 aataagcaat cttatagggc acaccaattt gatttaaact ggaagcaaac tgactaggat
     6721 gggttgtcat caaaaagata atagccagag gaatggtgca aagatactta atggccaaat
     6781 ttagcagata aaagagctcc tggctggtta gagtgtagac accgattccc tgccaaatca
     6841 cacttctctc tccataaagt ccaaccccat actcgggaga aaagagatag accatcaaaa
     6901 cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa ggaaacatct ttaaagcgaa
     6961 tttctgataa atagaggaga aagactgaaa agatggcaat cagcaagagc attctggtat
     7021 catagctaat catggccgcc aatgatacca gaatgaaaaa gagaagtttc ccagctcctg
     7081 acaagcgatg aatcacagta tctctatgct ggtaaccgat taatttagct tgcatccctc
     7141 tctcctttct ttgtaaaatg ccgttaaatc cagtggatcc acatctagtt tcttagccaa
     7201 gttaaagatg gaggtttctt ttagattggc ttttactaac agctcaggat cgctcaacag
     7261 actggctgga acagtatcgg caatcaattc tccatccacc atgacaagga cccggtctga
     7321 ataatccagc atcaattgca tatcatgggt aatcatgaca atggtatgcc ctttttgatg
     7381 taactcttcg agaaattcca taatctcagt atagttcttc tgatcttgac ctgcagtcgg
     7441 ttcatctagg agaataattt cagctcctaa gaccaaaatt gaagcaatgg tgacacgttt
     7501 tttctgacca aatgacaggg cagaaatagg ccaattacgg aattcataaa gtccacagat
     7561 tttcaaggtt tcatatactc tcgtttcaat ttccttctca tccacacctc gcaaacggag
     7621 ccctagagcc acctcatcaa aaatcatatt ggttgaaatc atttgattag gattttgtag
     7681 cacatatcct actcgttccg cccgctctgc aacagaatcg ccttttatat cctgtttttc
     7741 ccaaagatag cgtccttccg tctgaataaa gctacttata gccttggcta gagttgattt
     7801 ccctgctcca ttttttccga caatagcaat cttttcaccc tttttaatat ctaaatgtag
     7861 ggattttaaa atcggtctat catcataaga aaaagatact tcctctagtc taaagagtga
     7921 ctgcaatgct ggggtttctt ttgccagttc attctgcaac tgaacctgac cttttgagat
     7981 agacaagtta tccagattcg ctaattgttc ttccttgact aagtccacac ctaattgacg
     8041 gagagtcgtt agataaaggg gttctcgaat tccattttga gtcaataaat cagtcgcaag
     8101 caactggtca gggctcccat taaaaaggat acgaccatcg tttatcaaga caatccgatc
     8161 cacagggcga tgcagaacgt cctccaaacg gtgctcgata ataagagtcg tcgtcccctc
     8221 ttccttatga atctggtcaa tcaattcgat aatatcctga cctgacttgg gatctagatt
     8281 ggcgagtggc tcatcaaaca agagaatcgg actttcatca atcaagacac cagccagact
     8341 gactcgctgc ttttgtccac ctgacaaatc ctgaggacgc tgatccagta aaggaagaag
     8401 gtccagcttt tcagcccatt tataaacacg acctttcatc tcatctaggg ctgtcacatc
     8461 attttccaga gcaaacgcca aatcttctgc cacagacaag ccaataaact gcccatctgt
     8521 atcctgcaaa actgtgctaa ccagatgaga cttatcatag atgctcatat caaaggctgc
     8581 ttgacccttt atcaaaaatt ctccatatgt ctgacccttg taaatattgg gaataatccc
     8641 attcaaacac tgacccaatg tagatttacc tgatccagat ggtccaacaa ttaagacttt
     8701 ctctcccttg taaatggtca agtctatccc ttgcaaggtc ggttcttgtt gtgtttcata
     8761 ccggaaagag aaatccttcc actcaattat agcttctttc atcttactct cttcattcgc
     8821 ttcttagact tctattttat cataaatcaa gcccttcttg cagtctcttc tcttaaaatc
     8881 ttagcgccaa aaagattcct atcttagctt acttgcctaa ctaatctata aacatcgaaa
     8941 aagactagtt gcccagcctt ccccatcatt ttatactctt cgaaaatctc ttcaaaccac
     9001 gtcagtttcg ccttgccgta ggtatggtta ctgacttcgt cagtttcatc tacaacctca
     9061 aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa tttcaaaaca ctgttttgag
     9121 caacctgcgg ctaacttcct agtttgctct ttgattttca ttgagtatta gtcctttttc
     9181 aaacttcctg cacgagtttg ggttcctgca taggcaagta agagaagagt tcctgcaata
     9241 gctacagata caccattggc aattcccgca acaatccctt gtgcaaatac tttttctgcc
     9301 gcttcttgat aaatcacaac atctccaagt ggtgccaaga caccccaaac aagggcattt
     9361 gcaagtagtt gaatgagatt aaaaataaga atatctttcc agtcaaaaac actattgatc
     9421 acgcgaacgt actttctaaa aagtcccaca actaaaccaa agagtccgct agcgataatc
     9481 caagtccacc ataaaccata accaacaaga gagtccttga ttgcatgacc aatcaacccg
     9541 acaagcaaac cgataatcgg tccaaaaata atagaaagta gcgcttgtac cgcatactga
     9601 agctgtatgc ttgtatttgg aacaggggtt ggaatgttga tcatcccgat gacaacaaag
     9661 agggcagcgc caattccgac agcaacaact tgtttaattg taaatttaat ttccatacta
     9721 ttctcctatt ttatccttct attttcttta tttcaatggt ccaagatgaa ccgacaccta
     9781 cattataggc cttggcaaag gaaccttggt tgatagccaa acctaaacga tagagagagt
     9841 tgatgtaaag gatgggttgc ccaattctca catctgcaaa tgatttgcca tagacaacct
     9901 gattttgata gaccagcata tcagcatgat agatggtcac ttcaaaacga tcaccaaatt
     9961 ctggttccag cttgtaaaat tcttcccgtg tgatagaggt ccaaagcgaa ccgaaacgca
    10021 catccagaat atcaatggct cccttcacca gatgatcttc tatgatggtc gctacgactg
    10081 gaagctctac aatctgttcc acactgagct ctggccctac ttcctcaaaa gtaatgtgac
    10141 cactggccag tttagcacca gtataggcat agacatcacg accgtggaag gtataagaat
    10201 gctctgtgtt ttgacgccta ttggccacct cagaaatctc acgaatggct acaatgccaa
    10261 cgtgtttctt gataaaggaa agcgtcccat tatctggcgt gacaatgtat tgattttttg
    10321 cagtcttggc aactacactc ttacgtttcg aaccgacacc tggatcgaca accgatacaa
    10381 acgtcgttcc ctcaggccag taatccaccg tctgaaagag acgatagctc ccctcaaaaa
    10441 tattataagg cgtgatatcg tgcgtcaagt gatggatttt taaggttgga gactcttcta
    10501 aagccactcc aatcatagcc gataccgcac catcaaccag accaaagtct gattgtaata
    10561 ccagtaaatt attattcatt ttatctcctt gtatatcctt tatcatacca tatttcagag
    10621 aaagtcgcta atagctattt caattggtta gggtatagtt ttaccttata gcaaatttcc
    10681 tactaaaagt tcttgttatt agctagtagg tgcttttttt cttgaaaaag ggtatgatag
    10741 ttacatcatg aaaaagtagg ttttattatg aaaattatcc ttgtcggagg gggaaaagtt
    10801 ggttttgccc tctgtcgctc cttggttgca gaaaagcatg atgttttgct gattgagcaa
    10861 gacgaagctg ttctcaatca tattgtcagt cgctttgata tcattggtat ccttggtaac
    10921 ggggccgatt ttgccattct tgagcaagcc agcgtccaag attgtgatat ctttatcgcc
    10981 ctgactgagc acgatgaagt caacatgatt gcagcagttc tagccaagaa aatgggagct
    11041 aaagaaacta tcgttcgggt gcggaaccct gaatattcta actcttattt caaggaaaag
    11101 aatattctcg gtttttctct tatcgttaat cctgagctct tggctgcccg cgctatcgcg
    11161 aatatcattg acttccccaa cgccctgtct gtcgaacgct ttgctggtgg acgcgttagc
    11221 ctcatggaat ttgtcgtcaa gtccaccagc ggtctttgcc aaatgcccat ttctgatttt
    11281 cgtaaaaaat ttggtaatgt cattgtctgt gcgatagaga gggatcatca aattatcatt
    11341 ccaagcggtg acatgactgt acgggataaa gatagaatct ttgtcactgg taaccgtgtc
    11401 gatatgatac tcttccataa ttattttaaa tcacgcgccg tgaagagcct tctcatcgtt
    11461 ggggcaggta gaattgccta ttatctactt ggtattctca aagatagtcg tatcgataca
    11521 aaagtcattg aaatcaatcc tgaaatcgcc agcttcttta gcgagaaatt cccaaatctc
    11581 tacatcgttc aaggagatgg aaccgcaaaa gatatcctgc tggaagaaag tgctcaacac
    11641 tatgatgccg ttgcgactct aacaggagtc gatgaggaaa atctgattac atctatgttc
    11701 cttgacaggg taggtgtaca gaaaaatatt actaaggtca atcgtaccag tctcctcgag
    11761 attatcaatg cgcctgattt ttcaagtatc atcacaccta aaagcatcgc tgtagatacg
    11821 attatgcact ttattcgtgg tcgagttaat gcccagtatt cagaccttca agccatgcac
    11881 catctagcca atggccaaat cgaaaccctg caattccata tcaaggaagc caataaaatg
    11941 actgccaaac ctctttctca actgaaattg aaaaaagggg ttcttattgc agccattatt
    12001 cgaaagggca agactatttt cccaactggg gaggatatgt tggaagttgg agacaagctc
    12061 ctagtaacaa ccttgttgcc aaacatcacc aagatttatg acttgattgc gaggtaagaa
    12121 atgaataaaa gtatgattcg ttacctcctt tcaaagttac ttttgattga agctgttctc
    12181 ctcttggttc ctgtggctat cgctgtctat taccgtgaat cgagccaagt ctttacagcc
    12241 ctcttttcga ccatagggat tctcgtattg ttaggcggtt cagggaattt acagaagcca
    12301 aaaaatcaac ggatttatgc caaggaggga gtcttgatcg ttgccctctg ttggatcctt
    12361 tggtctttct ttggtggtct cccctttgtc ttttctgggc aaatccccag ccttattgat
    12421 gccttttttg aaattagttc tgggtttaca actactggag caagtatttt gaacgacgtt
    12481 tcggttctca gccgttccct cctcttctgg cgaagtttta cccacttgat tggagggatg
    12541 ggagtgcttg tttttgcact tgctattatg gacaatgcca aaaatagcca cctagaggtg
    12601 atgaaggctg aggttccagg tcctgttttt ggcaaggttg tatccaaact aaaaaacact
    12661 gcccagattc tctatctcct ttatctagct ctcttctccc tctttgtcat catctattat
    12721 ctagctggta tgcctctcta cgatagtttt gtcattgcta tggggacagc gggaactgga
    12781 ggctttaccg tctataacga cggaattgcc cactatggca gctcactgat tacctatctg
    12841 gtcagtatcg gagttctggt ttttggggta aatttcaacc tctactacta cctcatgctc
    12901 cgtcgcatca aggccttctt tggtgacgaa gaacttcggg cttacttggt cattgtactg
    12961 gtttctacag gcttgattag cctcaacacc ctctacctct acccagggtt ttcaaagagc
    13021 tttgaaatga ccttcttcca ggtttccaac atcattacaa caactggttt tggatatgga
    13081 gatattacca actggcccct cttctcccag tttatcctcc ttttcctcat ggcaatcggt
    13141 ggctctgctg gatcaactgc aggtggactc aagattattc gaggcctcat cctttcaaaa
    13201 attgccaaaa accaaatttt gtcaatccta tcgccccacc gtgttttgac cctccatgtg
    13261 aatcaaacgg tgattgataa agatacccag cataagattc tcaagtactt tgtcatctat
    13321 gctatgattt tgctagcgct tatctttatt gtcagcctag atagcaatga ttttctggtc
    13381 gtgaccagcg ctgtctttag ctgtttcaat aacatcgggc ctattctagg aaccacttct
    13441 agtttctcaa tctttagtcc catctcaaaa attctcctct cctttgcaat gattgcaggg
    13501 cgcttggaga tttacccaat cctccttctc tttatgaaaa gaacttggtc taagagataa
    13561 aatacaaaat ccctcttttt acaattgtaa aaagagggat tcttatatta aaaaaagggg
    13621 gaacgttttt aaatccaagc ctgtctgtaa gcaaagtcct tactcaaata aaagatggaa
    13681 aaacttacta cacagcttgg taatgctcca atacaaattg taaggattta cttggattct
    13741 ttgttaaatg aatatattcc attcctctgg tagcaactat ctgaatacct aatctttctg
    13801 catccacctt catctctcta taataactcc gaacttgtgg ggccagaata attaaatcat
    13861 aaacacccat aatatcataa tgagctccgt acgctcctga attcgcaatc actctaacct
    13921 ctgttaagtt agccccctcg ttaattgcat tggctaattg cgcacttgtt ccagaccctg
    13981 cacaaagaac cagtactttc aactccttac tttttatttc atctaactca ccaggcatta
    14041 tttcacttgt atcctcctct aaaataatac catttgagct tgcaatatct tctttcacca
    14101 gtaactgtct atcatacgct ctacagaatg gcaaataaat caatatgtcg acaactaaaa
    14161 tcaaagataa aaatacaaag gagataagtt gaaaattcgt tccaattaac aatcccaagg
    14221 gaccaggaaa ggcccaaggt aactggatat aaaatccatt cattccaaag aaatcaataa
    14281 atacctttcc tagaaataca ttcactggtg gagtcatcaa aaaagggaca aaaagatagg
    14341 gattcaaaat aacaggcata ccaaatagaa gaggttcatt tactgcaaat aaaacaggag
    14401 taattgtagc tttacctacc gattttaatt gtttagaccg cataaagaaa atcaaaataa
    14461 atggtacaac aaaggtagcc cccgttcctc caatagcagc gatataattc ccgaaattag
    14521 gtgttaaaga atgataaggg aactgcccat ttgcaagaag ttgagcattc tcttccatat
    14581 tgctcagttg taaagctgta acagcaggta agacaataga tggtccatga attccaacaa
    14641 accaaagcaa agcacacata aaccaaatca acatcatagc aggatatgat tctgccccct
    14701 taaaaatagg agtcaatagt tgttgaaata cttgggcaaa aggaacatct aaactaaacc
    14761 gagatacaat atctaacaaa ccactaataa gtaaaacaaa agaaaaagga aaaatatctc
    14821 taaaagcttg tgatatagcc ccaggaactt ccttaggtaa atgaatagta atgtctcgct
    14881 taatacagaa tcggtaaaca tttacagtaa taaaggcact gacaaacgaa gttatcaatc
    14941 cttgagatcc taaatagttt gtcgacaaac ttgtagatcc tgtcttctca tcaactacaa
    15001 gcgttacagt taataccaga taactacata tggctgccaa cattgcagaa gtatcattta
    15061 ttacctttcc gtgaggcatt tttctgttaa catttccaac taatgacttt ccaacagtcc
    15121 ctgaaacaat aatacccaaa actcccatgg ttaacatata cacttttctc atccagacaa
    15181 tagctggact cggtaactct actccgaaat ttttaggaat cataataata atcatcaaaa
    15241 agcttgaaaa cataattaaa ggcatagtag caatgaatcc atctttaata gccatcatat
    15301 agttattagt agaaattttt tcaaatttcc cttgttgctt ttcaatggca gcgactagct
    15361 tatccataaa actcctccta taaaaaattc aacctcatat ttaaaacata ttaaacatca
    15421 gtcaaatcgc taaccttaat tccgttttag cccttttacc caaagagcac ttttcttaat
    15481 atatctcttc tgtgtttcat aatcaacaaa gaaaagacca tatcgcttat tgtagccatt
    15541 cgcccaagaa aattgatctt gcaaagacca tataaaatag ccttgaatat tgactcctct
    15601 atctcgagcc tctaaaactt tgtgtaaatg ttgctcaata taacgaattc tcttactatc
    15661 atcaataata tcattctcgc cctctggctt aacctcttta agggctgtac cattttcagt
    15721 taaataaatg accggatgtt gaggatattc ttctttgata cgaagcaaca tatcaaataa
    15781 gccttgagga taaatattcc aatcccaatc tgttgtcgga ataccaggct tttttacaaa
    15841 ttcacctaga gcatttaatt taaaagaaga ctgtcctttt attcctgttg aattaaattc
    15901 ttgtctattt tcacctttgt attcacgaat aaattctgaa cgataataat tcatcccaaa
    15961 catcgtatta agagctgcag ctctcttcat aatttctaaa tcaccatctt caataataaa
    16021 gctagaatta ttagcttcca atatttgatt caagtgaaaa agcgtgtcct cactgtagta
    16081 gcccaaaaaa gttccatcta atagaaattt attattataa acatcatacc gtttagctgc
    16141 caaaatattt tctttttgcc catcaatagg atagcctggc tttaaagcat gaatacaacc
    16201 tacctttccc tcaatcccta attgatgaaa ttcgaggact gcaagagcat gcgccaacaa
    16261 catattatga ttcgcttgaa ttgcttcaga taattgaaaa tggtgattcg gaggaaactg
    16321 acctcctatg tattgacctg cagcaagaga catcagttca ttgattgtaa accaatgctt
    16381 gacttctgta aattcttgga aacaaaagcg agcatatcgt atgaaacgat caatattctc
    16441 tctattcaac caatcccctg tttctaacat tttctgaggc gaatcaaaat gatgtaaaga
    16501 aacaaacgga atcacattat attttaagca ggactgaaag actctatggt aataacgaac
    16561 agccaatata ttcggcgccc catctatatc aggaaatata cgaacccaag aaatagataa
    16621 acgcaaagcc tgcaaaccat gttctgccgc caaagctata tcctcttcgt aacgataata
    16681 aaaatcacta gctggatctg gtaagaacgg actattttct tgcaaataaa catcccacat
    16741 atttattcct ttgccatcta ccctagttgc accctctact tgataagcag cggtagcagc
    16801 tcctaataaa aactccttca gtaaggcttt aatctgtaaa ttttccatga ctaatcctca
    16861 ttgcaaacca atatgttctt caatctttcg aattcgttca tattcatcaa taaaaaactt
    16921 tacctgatca tacaatagca tcgttgtcat caaagtatct tgaccatgaa tcatgataaa
    16981 actcacttca aaattatctc cagatgcctc ctccgctaat aaattagtct gttctcgatg
    17041 ggcagacact attgagtcgt ttgcagactc aaccaattct cttgcctgtt caaaatatcc
    17101 atctctcgca aacgccaaag catccatcaa atctgacctt gcatctcctg cgtaagcgac
    17161 aattgtaaaa ccaagcatat ttatttcttc ttttgatttc atctttcttc ctcctcaatc
    17221 ttgatccatc ttttacacat cattattaaa atgacttcgc tacgatacaa atagaaagtc
    17281 gaccctaaat atcttaaaaa tccttaaaaa tccttaaatt tcataatatt tagggtcaat
    17341 cttctctgaa taccttagtt cattttctat acttatgatt tataagtgga aaccagcgta
    17401 attttttgct acttcaatta cacgataaac atccaaatta gattgaaata gcaattcgtg
    17461 cccacggata taattcaaca catttctcca ttcatcctga gcttgccttg tttttccagt
    17521 tgcttgaaga tataaagcct tcgccatctt aacaacatat tcacgatgat aactgagctg
    17581 tttccattca tccttttgac tatttaataa cttagaaata ttttcctcaa caattggtaa
    17641 aaaattatca gctagattgt aagctatata ataatgattc gctaaaacat cattttgacg
    17701 actgccaatt gcattaaaat agtcacaaga ggaataaatg gataattttt ctaaatattc
    17761 aacaacagac tgccaatttt ccccatacaa agcaaaaaag tattcttcaa tcaattcttc
    17821 ataacttctt gtcttcttcc agagcatttg ccccatgaca taattaggaa aattatgagg
    17881 gaatccggca cgtaattctt gacacgaaat gtacccattc aaatgtaggt ttgaaagata
    17941 agatacatct ctgtaaatag tttgactaat tttcatatag cctaaatcgc cataatgagc
    18001 acgccctaaa ggatagtcat atacgaaact atctccttta aatgtttttt gccactcaaa
    18061 aagataagat aaattttcct caagagaatt cggaagtata attttattac gcatataagg
    18121 tttaggcgta ggtatggaat tgtcaaaatc tacatctgca taactcattt caaatgttct
    18181 tgtaatcggt gcaaacatca tggtaaagcg ttcaggatta tctaattttt ctttctgagg
    18241 cgcccataac aactcatggt aaagcagaaa acaaatcttt gtatctaatc cctcactcgt
    18301 taaagcccta tccaattgat tgagaatacg aatatactga tccgaaacca attcttgtct
    18361 acagttttcg cattcacaaa tattattacg agcatccgac aaccatacat gtaagtagtt
    18421 aacatcaggt cttttcttgg cataatcctt gataatttct accatcttat ccgccacatc
    18481 tggatttgaa aaatccagac tggttaaaat cggagccgta ttaaataatt ctcgtttccc
    18541 gtttatttca gcgacatagg gtttcttctc ctctgaaata ctaagacctg attcccagcc
    18601 aaattttgaa gagtaaccta aaacctcacc tgtccatcca tgaccaacac gatgatgaat
    18661 aagacctctt ttttgcaatt ctttatccaa cctatcactc aattcttgta ctaattcatt
    18721 tgagaatttt tctttattta ggtatggatt aaactcatgt tcataccaac gtttcaaaaa
    18781 agaataggga ttttcaaact ggatgaaaaa actgttcatc ccaatcttag gtagccaatc
    18841 aatgaaatct agtatatttt caaatgaatc tgctccctct atacatactc ccctatgata
    18901 gtaactggct gtttcatcta tagatagctc tttatctaaa aaatcttcaa atcgtaactc
    18961 tggaacaaag tcatgtccgc gccctggtct agtatacaca accccaaatt catgaaacat
    19021 tcggtaaatt ccaataagta aacctacaat tgtattagac tcaattctcc ccttaccctt
    19081 gtctaatgag ataagaacat ggtcttttct atcctcttta ttgactaatc ctacaaaaat
    19141 atccgcttcc ttctcctcga caagttctat gtcagtctta aagacccgat ttatatagta
    19201 acttaattcc tctaaggcaa agctagaata agtatttttc tgctgatcaa atactctgat
    19261 aaccatctta tttccctcca acagtagctt tttctttttc aagattgcgt ttatctgcaa
    19321 ttttgaagaa tggataataa attgctacag aaaccaaaat caaaacaact tgtaatagag
    19381 ctcctcgcca actagctcct gtcgcaagga agcctcctat gatcggtggc attgtccacg
    19441 gaaggattac acctgttgtg tagggtacta atcctacagc cattgataca taggtaatta
    19501 aggcattgat tgtaggagta gcaataaacg gaatcagcat aatcggattt aaaactgttg
    19561 gaaacgtaaa tagaatagct gtattgatat taaaaataga cggtataata gctagcttac
    19621 ctaatgtttt attcgcacga ctcttactaa ataggaagag acaaatcgca agaccaatag
    19681 tcgctccacc gccaccaata aatacaaata aatctttaaa cggtaatgta ataatgtgtt
    19741 ggagtgtttg tcctgcagcc acagcttctt ggttttctgt agtaaattgt aaccaaactg
    19801 gatctacaaa agcatttaaa acttgtcccc cattaactcc acagaaccaa aagaatgagt
    19861 ttacaataac acatagaatc atacctggaa gcgttcctgc aattaactta agcggtgttc
    19921 caacaattgc acctaggagt ccgttgagac ctcctgcaac tcctgccgct tcaagacctt
    19981 ttaagaccag agcccacaaa acaaaagtag taaagccagg taaaagagct gaaaatgatt
    20041 tacttaccac atctgggaca ccacttggca tttttatcgt aattccgcgc tggataaaca
    20101 tacgataaat ctctgctgta accaatccaa tagtaatcgc cataaacaaa gaagatgcat
    20161 tcaggctaga aaatggtatt gcgccgccaa ataactgctt gacctgctcc ccatttttat
    20221 cataaaccat actcgaaaaa cgaggtgcca tcaatacaaa actggataag gctatgatcc
    20281 ctgccgacgg accatctgta ccatatcctt ccgacaacct gtaggcaata ccgaaacaag
    20341 cgaccaagga gataatcgct actgttgact gattcatagt tgtcaagata cttagcaatc
    20401 caacactatt cagccaattt gtaaaatcct cttgaggcca actgattaga ataagaaata
    20461 aagatccgac taaaatcaaa ggcattgcca tcataaatcc ttcacgaata gctttcaaat
    20521 gccgttggtt gccaactttt tcaccaaacg gagcgacttt tgtttctaaa aacgctaaaa
    20581 tattgttcat caccggaact ccttttttta ttttttataa attaaatata ccactaacag
    20641 aaagcgttgt caatatattt tt
//
LOCUS       DAVLUM010000039        20264 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLUM010000039 DAVLUM010000000
VERSION     DAVLUM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.039"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            237..584
                     /gene="ssrA"
                     /locus_tag="VYN42_001270"
     tmRNA           237..584
                     /gene="ssrA"
                     /locus_tag="VYN42_001270"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(828..1604)
                     /locus_tag="VYN42_001271"
     CDS             complement(828..1604)
                     /locus_tag="VYN42_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HEV1462340.1"
                     /translation="MNATDIKNTYLNYIKENAVFNDVTDTHTEVITPFIDPLGEAIGF
                     SIKSNGKHLTVTDDGYTIWNLSINNIDVTKKGRRQDIFNSLLHFNGFDLHDGAIERTT
                     GKEHLGQVIHDMTQLLMNVYDFIQLTPNNIKSQFLDDVKSYFMKNEHYTVFPAFSIAG
                     KSRLEHRFNFVFMSKGISKIARVHNNITKQQVDTILASWLDTSEYRRKEYGDTEQLYI
                     IVSDEGYNNIKDDHQIALQEYGINILNFSDKEQLEIQLGK"
     gene            complement(1631..2101)
                     /locus_tag="VYN42_001272"
     CDS             complement(1631..2101)
                     /locus_tag="VYN42_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462341.1"
                     /translation="MKELLLTDSEAKALIKIIKAIANKHNRTLTNRSSGTINLVGKHD
                     TRFILNYFYSTTSKVFHLRETQHNYTLLRINLNNKFHKNANGEKVWGNRVNIFSEEEY
                     YQKGDETTHYKAYPLPYEDILNTDDFLDMLDNLLDYTNVNNPENIAINIQEDLL"
     gene            complement(2156..2620)
                     /locus_tag="VYN42_001273"
     CDS             complement(2156..2620)
                     /locus_tag="VYN42_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HEV1462342.1"
                     /translation="MSKVVKVTGAEVVISHNEEYLKVNPSELNFVPKLGDEVEVHKVD
                     GEIIVIKVKDKKDDKININIVNENNAMQNQSQVVHTQEIATGVHYVNKWVYVILALFL
                     GGLGIHHFYAGYNGKGFLFLILSLTGIPAIIALFQGIIALFKKPDVYGRIAV"
     gene            complement(2976..3063)
                     /locus_tag="VYN42_001274"
     tRNA            complement(2976..3063)
                     /locus_tag="VYN42_001274"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3027..3029),aa:Ser,seq:gga)
     gene            3226..3966
                     /locus_tag="VYN42_001275"
     CDS             3226..3966
                     /locus_tag="VYN42_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1462343.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            3963..4874
                     /gene="pfkB"
                     /locus_tag="VYN42_001276"
     CDS             3963..4874
                     /gene="pfkB"
                     /locus_tag="VYN42_001276"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1462344.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            4871..6823
                     /locus_tag="VYN42_001277"
     CDS             4871..6823
                     /locus_tag="VYN42_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1462345.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAAMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLAISGDAEVYRAANGAK
                     VATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVACSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGSLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            6987..9212
                     /locus_tag="VYN42_001278"
     CDS             6987..9212
                     /locus_tag="VYN42_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1462346.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALKYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(9256..9684)
                     /locus_tag="VYN42_001279"
     CDS             complement(9256..9684)
                     /locus_tag="VYN42_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462347.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            9847..11931
                     /locus_tag="VYN42_001280"
     CDS             9847..11931
                     /locus_tag="VYN42_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1462348.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKVSALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GDLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            11941..12318
                     /locus_tag="VYN42_001281"
     CDS             11941..12318
                     /locus_tag="VYN42_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462349.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            12478..13620
                     /locus_tag="VYN42_001282"
     CDS             12478..13620
                     /locus_tag="VYN42_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1462350.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLVGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            13629..14843
                     /gene="thiI"
                     /locus_tag="VYN42_001283"
     CDS             13629..14843
                     /gene="thiI"
                     /locus_tag="VYN42_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1462351.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            14978..15802
                     /locus_tag="VYN42_001284"
     CDS             14978..15802
                     /locus_tag="VYN42_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1462352.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            15824..16159
                     /locus_tag="VYN42_001285"
     CDS             15824..16159
                     /locus_tag="VYN42_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV1462353.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGLVQFFTLSSLDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSLMA"
     gene            16156..16563
                     /locus_tag="VYN42_001286"
     CDS             16156..16563
                     /locus_tag="VYN42_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1462354.1"
                     /translation="MMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYY
                     NDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQK
                     QIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            16576..17742
                     /locus_tag="VYN42_001287"
     CDS             16576..17742
                     /locus_tag="VYN42_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1462355.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            18250..19743
                     /locus_tag="VYN42_001288"
     CDS             18250..19743
                     /locus_tag="VYN42_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1462356.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            19756..>20264
                     /locus_tag="VYN42_001289"
     CDS             19756..>20264
                     /locus_tag="VYN42_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1462357.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLV"
BASE COUNT         6135 a         3615 c         4286 g         6228 t
ORIGIN      
        1 atctgaaagt attttagaat aattctcttc gtgaatttct tcaaaacaga tagcttcatc
       61 ttaggtatgt gttaattgga tttcgtaagc tctatttaca atcgtaaagt tatgcactga
      121 aaaagttgta gttagtcttc cagtttgcta aatttctcga atagtatctt ttttaggtat
      181 gtgatttctt tttgcatttt tgagttagat aaggtataat ggttttattg tcttttgggg
      241 tcgttacgga ttcgacaggc attatgaggc atattttgcg actcgtgtgg cgacgtaaac
      301 gctcagttaa atataactgc aaaaaataac acttcttacg ctctagctgc ctaaaaacca
      361 gcaggcgtga cccgatttgg attgctcgtg ttcaatgaca ggtcttatta ttagcgagat
      421 acgattaagc cttgtctagc ggcttgataa gagattgata gactcgcagt ttctagactt
      481 gagttatgtg tcgaggggct gttaaaataa tacataacct atggttgtag acaaatatgt
      541 tggcaggtgt ttggacgtgg gttcgactcc caccggctcc attattcctt tgcattcttt
      601 tgcattcctt ggtaaaacgt tgttaaatca acgtttttta tttttatctt tggtattcct
      661 ttgcattctt ttgctaaaaa gggagtcaca aacagaccct attttaaaaa aaggatagaa
      721 aaaaggatac aacatttgtc gcatcctaga aatctatgta cttcgtaaag cgttctccga
      781 ttcgagtatt cctctgcatg ctttagtaaa tataggattt tttgtagtta cttccctaat
      841 tggatttcta attgttcttt atctgagaaa ttcaaaatgt taataccata ctcttgtaga
      901 gcgatttgat ggtcatcttt gatattatta tacccttcat cgcttacaat gatatacaac
      961 tgttctgtat ctccatattc ttttctacgg tattcagatg tatctaacca actagctaag
     1021 atagtatcaa cttgttgttt ggttatgtta ttgtgaactc tggctatttt tgaaatacct
     1081 ttactcataa acacaaaatt aaagcggtgt tctaaacgag atttacctgc aattgagaaa
     1141 gctggaaaga ctgtgtaatg ctcatttttc atgaagtaag atttaacatc gtctaaaaat
     1201 tgagatttaa tattgttagg tgttagctga ataaagtcat aaacattcat cagcaattgt
     1261 gtcatatcat gtatgacttg tcctagatgt tctttaccag tcgtccgttc gattgctcca
     1321 tcgtgtaaat caaatccatt aaagtggaga agtgagttaa agatgtcttg acgtcgccct
     1381 ttttttgtaa catcaatatt attaatggat aaattccaga tagtataacc atcatctgta
     1441 actgtcaaat gttttccatt gctttttatt gagaaaccaa tagcttcacc taatgggtct
     1501 ataaaaggag taatcacttc agtatgagta tcagtcacat cgttaaaaac agcgttttct
     1561 tttatgtaat ttagataggt atttttgata tcagtagcat tcatgatatt ctcctttctt
     1621 tatagggtga ttataacaaa tcctcttgta tattaattgc tatattttca ggattgttca
     1681 cattggtata gtcaagcaaa ttatcaagca tatccaggaa gtcatcagtg ttaagaatat
     1741 cttcataagg tagtggatag gctttgtaat gagttgtttc atcccctttt tgataatact
     1801 cttcttcaga gaagatgtta actcgattgc cccaaacttt ctcgccgttt gcgttcttat
     1861 ggaatttatt atttagattg attcgtaaga gagtatagtt gtgttgagtt tcccttagat
     1921 gaaaaacttt gcttgtagtg ctgtagaagt agttcaaaat aaatctagta tcatgcttgc
     1981 caacaaggtt aatagtacct gaactgcgat tcgtaagagt tcgattgtgt ttattagcaa
     2041 ttgctttaat tatttttatg agagctttag cttcactatc tgtcagaagt aactctttca
     2101 tatctttcct ttctacttta tctacattct agagagtgga aatctggaat gtagatcaga
     2161 cagcgatcct tccgtataca tctggtttct taaagagagc tatgatgcct tggaaaagtg
     2221 caataatagc aggtattcct gttaaagata aaatcagaaa aaggaaacct tttccgttat
     2281 atcctgcgta aaaatgatgt atacccaatc cacctaaaaa taaagcaaga ataacataaa
     2341 cccacttatt aacataatgt acacctgtag ctatttcttg agtgtgaacg acttgtgact
     2401 gattttgcat agcgttgttt tcattgacaa tgttaatatt aattttgtcg tcttttttat
     2461 ctttaacttt tatgacgata atctcaccat ctactttatg aacttcgact tcgtcaccta
     2521 attttggaac aaaattcaat tcagatggat ttacttttaa atactcttca ttatgggaga
     2581 ttacaacctc tgctcctgta actttaacaa cttttgacat tttgtttttc ctttcatttt
     2641 accatctata gattttaata atgagctttg atatttattt tatctgtttt tataagtaaa
     2701 gtatatcaaa aaaagtacga aaagaaaatc ttttatggtt tagttaaaaa gcaagagttt
     2761 aagaaactgg attaattaaa cttgaagtat ttgagatttt gtcttttact gttcgtaaaa
     2821 tcgtatgaga taagaaggga gtggaaagaa ttcatactct ctctagaact tgtatattga
     2881 aacgatgtgg agattgtaaa gaaattacaa aataccccaa aactaagata gaaatacaaa
     2941 gtttcagggt atcatatatt ttatctgttt ttcgacggaa gacatgggat tcgaacccac
     3001 gcacgctatt acacgcctac cgcgtttcca acacggcctc ttaagcctct tgagtaatct
     3061 tccaatactt actcaaatag tctaccataa aggctcttat cttgcaataa aaattctaga
     3121 aataagaaaa aatgatagat tttgaaagaa aatgataaaa aatgcttgac ttcgaaagaa
     3181 agtatgatag aatgaatagt gtaaacgata acaggaggtg attcagtgtt aaaaacagaa
     3241 cgtaaacaac taattttaga ggagttaaat caacatcatg tagtttctct agaaaaatta
     3301 gttagtttgc tagaaacgtc agaatcaacg gttcgaagag acttggatga gttggaagcg
     3361 gaaaacaagc ttcgtcgtgt gcatggtgga gcagaactcc cccactcctt acaggaagaa
     3421 gaaaccattc aagaaaaatc tgtcaaaaac cttcaagaaa agaagttgct ggctcagaaa
     3481 gcagcctctc tcattaaaga aaaagatgtc atctttatcg atgctggaac aacaactgct
     3541 tttttgattc atgaattggt caataagaat gttacagttg tgaccaactc cattcaccat
     3601 gccgctcagt tggttgaaaa gcagattcca actgtcatgg ttggaggaaa cgtcaagacg
     3661 gcgacagatg ctagtatcgg gggcgttgct cttaaccaga ttaaccaatt gcactttgac
     3721 cgtgccttta tcggaatgaa tggtgttgac gatggctatt atacgactcc tgatatggag
     3781 gagggagctg tgaaaagagc tattttggag aatgccaagc agacctacgt cttggtggat
     3841 tcgtcaaaaa ttggacaaac ttgctttgcc aaggtagcac cactcaaacg cgctatcgtt
     3901 atcactagtc aagggcatga gctcttgcag gttattaagg agaaaacgga ggtaatagaa
     3961 gtatgattta tacagtcaca ctcaatccat ccattgacta tatcgttcgt ttggaccaag
     4021 tcaaagttgg tagtgtaaat cgtatggaca gtgatgataa gtttgctggt gggaaaggaa
     4081 tcaatgtcag ccgtgtcttg aaacgtttga atataccaaa tacagcgacg ggatttatcg
     4141 gtggctttac tggtaaattt atcacagata ctttagcaga ggaagaaatc gagacacgtt
     4201 ttgtccaggt ggcagaagat actcgtatca atgttaaaat caaagcagac caagaaacag
     4261 aaatcaacgg aacgggtcca actgttgaat cggttcagct agaagaattg aaagctattt
     4321 tatctagtct gacagcagaa gatacagttg tctttgcagg ttcaagtgct aaaaatctag
     4381 gcaatgttat ctataaggat ttgatttcct tgacgcgcca gactggtgcg caagtggtct
     4441 gtgactttga aggacagacc ttaattgata gtttggacta ccagcctctt cttgtaaaac
     4501 caaacaatca tgaacttgga gcgatttttg gggttaaact cgaaagttta gatgaaattg
     4561 agaaatacgc tcgtgagtta ctggctaagg gtgctcaaaa tgttattatc tctatggctg
     4621 gtgatggtgc ccttcttgtc acatctgatg gagcttactt cgctaaacca atcaagggaa
     4681 cagtcaaaaa ttcagttgga gctggtgatt ctatggttgc tggattcaca ggtgaatttg
     4741 tcaaatcaaa agacgcagta gaagccttca aatggggagt ggcttgcgga acggcaacta
     4801 ccttctcaga tgacttggca acggcggaat ttattaaaga aacatatgga aaagttgagg
     4861 tagaaaaacg atgaaaattc aagacctatt gagaaaagat gtcatgttgc tggatttgca
     4921 ggcaactgaa aaaacagctg tcatcgacga gatgattaaa aatttgacag accacggtta
     4981 tgtaacagat tttgaaacat ttaaagaagg aattttggcg cgtgaagctt tgacttctac
     5041 tggtttgggt gatggaatcg caatgcctca cagcaaaaac gctgctgtca aagaagcgac
     5101 agttctattt gctaagtcaa ataagggtgt tgactacgag agcttggatg gacaagcaac
     5161 tgacctcttc ttcatgattg cagctccaga aggtgccaat gatactcact tggcagcctt
     5221 ggcagaattg tctcaatact tgatgaaaga cggttttgca gacaaacttc gtcaagcaac
     5281 atctgcagac caagttatcg aactttttga ccaagcttca gaaaaaactg aggaacttgt
     5341 tcaagcacct gctaatgact ctggtgactt tatcgtagct gttacagctt gtacaacagg
     5401 tattgcccac acttacatgg cccaagaagc ccttcaaaaa gtagctgctg caatgggggt
     5461 tggtatcaag gtcgaaacca acggtgctag cggtgttgga aatcaactaa ctgcagaaga
     5521 tatccgtaag gctaaagcta ttatcattgc agcagacaag gccgttgaaa tggatcgttt
     5581 cgatggcaaa cctttgatca atcgtccagt tgctgacggt atccgtaaga cagaagaatt
     5641 gatcaacttg gctatttcag gagatgcgga agtctaccgt gccgctaatg gtgccaaagt
     5701 cgcaacagcc tctaacgaaa aacaaagcct tggtggtgcc ttctacaaac acttgatgag
     5761 tggtgtatct caaatgttac cattcgttat cggtggtggt atcatgattg cccttgcctt
     5821 cttgattgac ggtgctttgg gtgttccaaa tgaaaacctt ggcaatcttg gttcttacca
     5881 tgagttagct tctatgttca tgaaaattgg tggagctgcc tttggtttga tgcttccagt
     5941 ctttgcgggt tatgttgcct gctctattgc tgaaaaaccg ggtttggtag caggtttcgt
     6001 ggctggtgct attgccaaag aaggttttgc ctttggtaaa attccttatg ccgcaggtgg
     6061 tgaagcaact tcaactcttg caggtgtctc atctggtttc ctaggtgccc ttgttggtgg
     6121 atttatcgca ggtgccttgg ttcttgccat caagaaatac gttaaagttc ctcgttcact
     6181 cgaaggtgct aaatcaatcc ttctattgcc acttcttgga acaatcttga caggatttgt
     6241 tatgttagct gtgaatatcc caatggctgc aatcaacact gctatgaatg acttcctagg
     6301 cagtcttgga ggaggttcag ctgtccttct tggtatcgtc cttggtggaa tgatggctgt
     6361 tgacatgggt ggaccagtta ataaagcagc ttatgtcttt ggtacaggta cgcttgcagc
     6421 aactgtttct tcaggtggtt ctgtagccat ggcagcagtt atggctggag gaatggtgcc
     6481 accacttgca atctttgtcg caactcttct tttcaaagat aaatttacta aggaagaacg
     6541 taactctggt ttgacaaaca tcatcatggg cttgtcattt atcactgagg gagcgattcc
     6601 atttggtgcc gctgacccag ctcgtgcgat tccaagcttc atccttggtt cagcagtagc
     6661 aggtggactc gttggtctta ctggtatcaa actcatggcg ccacacggag gaatcttcgt
     6721 tatcgccctt acttcaaatg ctctccttta cctcgtttct gtcttggtag gagcaatcgt
     6781 aagtggtgtg gtttatggtt acctacgcaa accacaagca taaaaaatag aaaaatgaaa
     6841 agattggacc gtttggtgca gtctttttct cttcccgaaa tgcctgtgaa atatggtata
     6901 atagaagaat ggcaaacaag aatacaagta caacaagacg gagaccgtct aaagcagaac
     6961 tggaaagaaa agaagcgatt caacgaatgt tgatttcgtt aggaattgcg attttattga
     7021 ttttcgcagc cttcaaatta ggggctgcag gtataaccct ttataattta attcgcttgc
     7081 tagtgggtag cctagcttat ctggcgatat tcggcctatt aatctatctc ttctttttca
     7141 agtggatacg aaaacaggaa ggactcttat ctggcttttt caccatattt gctggcttac
     7201 tcttgatttt tgaggcctac ttggtttgga aatatggttt ggacaagtcc gttctaaaag
     7261 ggaccatggc tcaggttgtg acagatctga ctggttttcg aacgactagc tttgctggag
     7321 ggggcttgat cggggtcgct ctttatattc caacagcctt tctcttttca aatatcggaa
     7381 cttactttat tggttctatc ttgattttag tgggttctct cctagtcagc ccttggtctg
     7441 tttacgatat tgctgaattt ttcagtagag gctttgccaa atggtgggaa gggcacgagc
     7501 gtcgaaaaga ggaacgcttt gtcaaacaag aagaaaaagc tcgccaaaag gctgagaaag
     7561 aggctagatt agaacaagaa gagactgaaa aagccttact cgatttgcct cctgttgata
     7621 tggaaacggg tgaaattctg acagaggaag ctgttcaaaa tcttccacct attccagaag
     7681 aaaagtgggt ggaaccagaa atcatcctgc ctcaagctga acttaaattc cctgaacagg
     7741 aagatgactc agatgacgaa gatgttcagg tcgatttttc agccaaagaa gcccttaaat
     7801 acaaacttcc aagcttacaa ctctttgcac cagataaacc aaaagatcag tctaaagaga
     7861 agaaaattgt cagagaaaat atcaaaatct tagaagcaac ctttgctagc tttggtatta
     7921 aggtaacagt tgaacgggcc gaaattgggc catcagtgac caagtatgaa gtcaagccgg
     7981 ctgttggtgt aagggtcaac cgcatttcca atctatcaga tgacctcgct ctagccttgg
     8041 ctgccaaaga tgtccggatt gaagcaccaa tccctgggaa atccctaatc ggaattgaag
     8101 tgcccaactc cgatattgcc actgtatctt tccgagaact atgggaacaa tcgcaaacga
     8161 aagcagaaaa tttcttggaa attcctttag ggaaggctgt taatggaacc gcaagagctt
     8221 ttgacctttc taaaatgccc cacttgctag ttgcaggttc aacgggttca gggaagtcag
     8281 tagcagttaa cggcattatt gctagcattc tcatgaaggc gagaccagat caagttaaat
     8341 ttatgatggt cgatcccaag atggttgagt tatctgttta caatgatatt ccccacctct
     8401 tgattccagt cgtgaccaat ccacgcaaag ccagcaaggc tctgcaaaag gttgtggatg
     8461 aaatggaaaa ccgttatgaa ctctttgcca aggtgggagt tcggaatatt gcaggtttta
     8521 atgccaaggt agaagagttc aattcccagt ctgagtacaa gcaaattccg ctaccattca
     8581 ttgtcgtgat tgtggatgag ttggctgacc tcatgatggt ggccagcaag gaagtggaag
     8641 atgctatcat ccgtcttggg cagaaggcgc gtgctgcagg tatccacatg attcttgcaa
     8701 ctcagcgtcc atctgttgat gtcatctctg gtttgattaa ggccaatgtt ccatctcgtg
     8761 tagcatttgc ggtttcatca ggaacagact cccgtacgat tttggatgaa aatggagcag
     8821 aaaaacttct tggtcgagga gacatgctct ttaaaccgat tgatgaaaat catccagttc
     8881 gtctccaagg ctcctttatc tcggatgacg atgttgagcg cattgtgaac ttcatcaaga
     8941 ctcaggcaga tgcagactac gatgagagtt ttgatccagg tgaggtttct gaaaatgaag
     9001 gagaattttc ggatggagat gctggtggtg atccgctttt tgaagaagct aagtctttgg
     9061 ttatcgaaac acagaaagcc agtgcatcca tgattcagcg tcgtttgtca gttggattta
     9121 accgtgcgac ccgtctcatg gaagagcttg agatggcagg tgtcattggt ccagctgaag
     9181 gtaccaagcc aagaaaagta ttgcagcaat aaaaaatagc ttctttccaa ggttggaagg
     9241 aagctatttt tctggttatt gattactttt attttctgaa gttggagtat tgggctgttt
     9301 ttcattttca gtggcaggtt tacttgtagc aggtgtagta gagtcctgag ttgctgtttt
     9361 ctgctcttct tttttctctt ccttgacgct agattttggc gtttcttctt gttgtgtttt
     9421 ttcttgagaa gtcttatttt ccttattggg actagtattt tcctgagggg attccttttg
     9481 aatttctttg acaattgttg tcgtctggct tgttgtaggt tcctttttag tatttttgtt
     9541 attatccaag gcgttcataa tcgtgatact agcggtaatc aagccaagga tactagcgat
     9601 agtcgcaacg gttttttgaa agactgtaaa gccttttttg atgtgttctg tttttggttt
     9661 tgaagttcta cgataattag acatacattc tctcctttaa ttaaaattta ttatacctca
     9721 tttctttaaa aaaatcttaa aaaaagagga gatttttcta cacgaacttc agtaattagt
     9781 tgaaataaaa tatgacttat gatataacaa aataaagaaa gcgatttcaa aaaaggaggg
     9841 cgttatatgt tcgaaattag aaatttgagt ctctcttttg caggcaggcg gttgctagag
     9901 ccaacagatt tgatatttga aaggggaaaa gtatatacaa tatatgggaa gtcaggcgta
     9961 ggaaagtctt ctttactgaa taaaattggt ttgctctctg ctacggatcc tagtgtttct
    10021 tatttcttcg atggaaaaga gattgatatc gaaaataaga aatcagtctc tgtctttata
    10081 gctgaagaag ttgcctttgt atttcagggg cgaaatctaa taaatgattt gaccgtattt
    10141 gaaaatttaa gactagcttt aaacttttat gacttgagtc cagatgaaat agaaagcaaa
    10201 attgatacag tattggcgga tttacagatt tcttctttaa agcatgctta tccagaagat
    10261 ttatccggtg gtgaagaaca acgagtggca atcgcaagag ccttagttac aggaaagact
    10321 ctcatcttag ctgatgaacc aacaagttct ttggataaag aaaatagaga aaaagtctcc
    10381 gccttgttaa ttgatttagc tcacaaatat cataaaattg tattgattgt ttcgcatgat
    10441 gaggcgatga ttgcaatagg agatgttcag cttcatttta aagaccataa attagttggg
    10501 aattgtctta ttttgaattc tgatgaaggg ataaaggatt ctaagaagtg gtcctcctgt
    10561 ttgtcgtctt ctcatacgaa gctatccgtt ttgaaacata gaaggccttt tttacctaga
    10621 ttattagcgt tttttatctc tcttgtagtt gctatagcag taacctctat taactttcag
    10681 tccttatttg cagataagta tcaccaactg gtgaacaact cactcgaaaa tggcttcttg
    10741 gtgattaatg attcgcttca tttacaaact acaaaagtgt tggatgattt tctcagtttt
    10801 gataaggagg aaatcacctc aattagcaca agtcagaata ttcaaaccgt caatccttat
    10861 atagagtttc tctctttggg tatgacgttt gataattcaa aagactattc acaacttcaa
    10921 aagaactttc agccaacttt gactattgat ggtcagacca gaagcttgac aagaaatttt
    10981 tcaattcaac ccttgtatca gacaaataca acacagaggc agatagagta ttttgatagg
    11041 agcaatgaaa aagggattta tctatctgag caattcattt cagatgaaaa attaccaaat
    11101 atagtttcgg gaactaccgt gacactgact ttttatattc caatttcttt atatgaatca
    11161 agtatagaga aagaggggaa tatattgaaa ggagatggcg atttatttgt caaagtggat
    11221 aaaacatatc ctgttttagg gattgttaaa aaaagttatc cgtttgaata ttccccttat
    11281 gggaacaccc tatttatgaa tattgctgaa atggaagaat tgcaaaatga agcaattcaa
    11341 cagcatccca tgacgaagat ggctttagat ggttttcctt tgaaatcatg gatgccgagt
    11401 gcgattcatg tgttactaaa ggatagcggt gctattcctg aagaattgag tagaataaga
    11461 gcaatctctt cacaaattac tattttatca tcatatgaaa actacgaaga atttaataaa
    11521 ggactcacct atatcaggca atttttaatg ttgctatccc tagtcttact catccttgtc
    11581 atcgcagtat tgtcctttgt tttctttttg ctcaatcgtc ctcgacgctt tgaagtaggg
    11641 attttaaaat ctttgggata cagtactcaa aatattgttt ggcttttctt aaaagaatta
    11701 attggttatg gtaaaacaat ttcgatatta gcaagttgtt tactcgtcat tctttccatt
    11761 ttagcaatgc aagtgcttaa attggaaatt tcagatgttt ttaaattcta tctaacttcc
    11821 gttttcacct taattggatt atcagtctca gtactgataa taagtggctt actacctata
    11881 tacacaactt gtaggcaaac agttgtcgat actatccgaa agaatggatg aggtgatatc
    11941 atgaaacata agataatgaa aaaaataata gtggtagtgt ttgctatccc atggttaaca
    12001 tttttaagtc aagtacatgc agattatgta agtaagtcta gttctttaga cggttatagc
    12061 ttggtaggct tgaatgttct taatgtgact tttaatgctt ctggctattc tgatacttat
    12121 agtggcagtg tgtcaaatat gtatttcact gactgggctt ggtttcctaa tacgataagt
    12181 aatcgttcca cttggaaaag ttcgattcca tatggtcaac gcgcaaatgg tacagtccat
    12241 ataggtgtag gagtaaattc gccttgggga gcggttaatc tctggggcgg acaaaattac
    12301 ttttctttag atttttaaca gaaataatca aagttagata gaatgaataa gaatgctctt
    12361 gatgatggta tcaagagtat tttatgttat tcagattaat gcaaacattg ccctttcttg
    12421 tcgcaggctc cgtttcatga tacaatagaa ggagtgattt tagaaagcgt gagaaacatg
    12481 atttactttg ataattcagc gacgaccaag ccttatcctg aagcccttga aacctatatg
    12541 caggtcgctt caaaaatttt aggaaaccca tctagtctcc atcgtttggg agaccaagca
    12601 acacgaatct tagatgcttc tcgccaacag attgcagatt tagtcggtaa gaaaagcgat
    12661 gaaatcttct ttacctctgg tggaacagaa ggggataact ggcttatcaa gggtgtggcc
    12721 tttgaaaaag ctcagtttgg caagcacatc attgtttcag ccattgaaca tccagcagtc
    12781 aaagagtcag ccctctggtt gaaaagtcaa ggatttgaag tggattttgc tccagttgat
    12841 aagaaaggct tggtcgatgt tgaggcgtta gcaggtttga tacggcatga tacaatcctc
    12901 gtttccatca tggctgtgaa caatgaaatc ggctctatcc aacctattga ggctatttca
    12961 gaattcttgg cagacaagcc gactatttcc ttccacgttg atgcggttca ggcgcttgcc
    13021 aaaattccga ctgaaaagta tctgacagaa cgggtggact gcgcgacttt ctctagtcac
    13081 aagttccacg gggttcgagg tgttggcttt gtctatatca aatctggcaa gaagattaca
    13141 cctcttctta caggtggtgg ccaggagcga gattatcgtt cgacaactga aaatgtggca
    13201 gggattgcag cgacagccaa ggccctccgt ttgtctatgg aaaagctaga tatctttagg
    13261 agcaagactg ggcagatgaa ggcagtgatt cgccaagctc ttctgaacta tccggatatt
    13321 tttgtctttt cagatgagga aaactttgca cctcatattc tgacttttgg aatcaaaggt
    13381 gttcgaggtg aagtcatcgt tcacgccttt gaagactatg atattttcat ctcaacaacc
    13441 tcagcttgtt catctaaggc aggaaaacca gccggtacct tgattgccat gggagtggac
    13501 aaagataagg ccaagtcagc tgtgcgtctt agcctagact tggaaaatga tatgagtcag
    13561 gtcgagcagt ttttgaccaa gttaaaattg atttacaatc aaactagaaa agtaagatag
    13621 gagcattcat gcagtattca gaaattatga ttcgctacgg agagttgtca accaagggta
    13681 aaaaccgtat gcgtttcatc aataaacttc gtaataatat ttcggacgtt ttgtctatct
    13741 atacccaagt taaggtaaca gcagatcgcg accgtgccca cgcttacctc aatggagctg
    13801 attacacagc agttgcagaa tctctcaaac aagtttttgg aattcaaaac ttttctcctg
    13861 tttataaggt tgaaaaatct gtagaagttt tgaagtcttc tgtccaagag attatgcggg
    13921 acatctacaa ggaaggtatg acctttaaga tttctagcaa gcgtagcgac cacaactttg
    13981 aacttgatag tcgtgaactc aaccaaacac ttggaggggc tgtattcgaa gccattccaa
    14041 atgtgcaagt tcaaatgaaa agtcctgaca tcaatcttca ggtggagatt cgtgaagaag
    14101 cagcctatct ttcttatgaa accattcgtg gggctggtgg tttgccagtt ggaacttcag
    14161 gtaaagggat gctcatgttg tcaggaggga ttgactcacc tgtagcaggt tatcttgctc
    14221 ttaagcgtgg ggtggatatc gaggcagttc actttgctag tccaccatat actagtcctg
    14281 gtgccctcaa gaaagcgcag gacttgaccc gtaaattgac caagtttggc ggaaatatcc
    14341 agtttatcga ggtgcctttc acagagattc aagaggaaat caaagccaaa gcgccagaag
    14401 cttatttgat gactctaact cgtcgcttta tgatgcggat tactgaccgt attcgtgagg
    14461 tacgaaatgg tttggttatc atcaatgggg aaagtctagg tcaagtagcc agccaaaccc
    14521 ttgaaagtat gaaggctatc aatgctgtta ccaacactcc catcattcgt cctgtggtta
    14581 ccatggacaa gttggaaatc attgacatcg cccaggaaat cgataccttt gacatttcaa
    14641 tccaaccgtt tgaagactgt tgtaccattt ttgcaccaga tcgtccaaaa acaaatccta
    14701 aaattaagaa tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg gttgagcgag
    14761 cagtggctgg aatcatgatt actgaaatca cacctcaagc cgaaaaagat gaagttgatg
    14821 acttgattga caatctgctc taattcagaa aatccaaaag aatagcgaaa atcagtaaaa
    14881 aaagttagtt ttttctctaa aaacaggtaa aaaactaact ttttttattt ttatgatata
    14941 atgatataaa attttgaata tagagagttt tctgacaatg aatcaatcct acttttatct
    15001 aaaaatgaaa gaacacaaac tcaaggttcc ttatacaggt aaggagcgcc gtgtacgtat
    15061 tcttcttcct aaagattatg agaaagatac agaccgttcc tatcctgttg tatactttca
    15121 tgacgggcaa aatgtttttt atagcaaaga gtctttcatt ggatattcat ggaagattat
    15181 cccagctatc aaacgaaatc cggatatcag tcgcatgatt gtcgttgcta ttgacaatga
    15241 tggtatgggg cgaatgaatg agtatgcggc ttggaagttc caagaatctc ctatcccaga
    15301 gcagcagttt ggtggtaagg gtgtggagta tgctgagttt gtcatggagg tggtcaagcc
    15361 ttttatcgat gagacctatc gtacaaaagc agactgccag catacggcta tgattggttc
    15421 ctcactagga ggcaatatta cccagtttat cggtttggaa taccaagacc aaattggttg
    15481 cttgggcgtt ttttcatctg caaactggct ccaccaagaa gcctttaacc gctatatcga
    15541 gtgccagaaa ctatcgcctg accagcgcat cttcatctat gtaggaacag aagaagcaga
    15601 tgatacagac aagaccttga tggatggcaa tatcaaacaa gcctatatcg actcgtcgct
    15661 ttgctattac catgatttga tagcaggggg agtacatctg gataatcttg tgctaaaagt
    15721 tcagtctggt gccatccata gtgaaatccc ttggtcagaa aatctaccag attgtctgag
    15781 attttttgca gaaaaatggt aagttaagaa aggaaaaaac gaaatgcata ttgaacatct
    15841 tagccactgg agtggtcatc ctaaccgtga aatgtacctt aaccgttatg gacatggtgg
    15901 gattccagtt gtggtctttg cttcatcagg tggtagtcac aacgaatact atgattttgg
    15961 catgattgat gcctgtgctt cctttatcga ggaaggcctt gtccagttct ttaccctatc
    16021 tagtttggat agtgagagct ggttggctac ttggaaaaat gctcatgacc aagcggaaat
    16081 gcaccgtgcc tacgaacgtt atgtgattga ggaggccatt cttttatcaa gcacaagaca
    16141 ggttagtttg atggcatgat gacgacaggt tgctctatgg gagcctatca tgcactcaat
    16201 ttcttcctcc agcatccaga tgtctttacc aaagtgattg ctctcagtgg tgtttacgac
    16261 gcacgtttct ttgtcggtga ttactacaac gatgatgcta tttaccaaaa ctcgccagta
    16321 gattatattt ggaaccaaaa cgatggctgg tttattgacc gttaccgtca ggcagagatt
    16381 gtgctgtgta cggggcttgg agcctgggaa caagatggtt taccatcctt ttacaagctc
    16441 aaagaagcct ttgaccagaa acaaattcca gcctggtttg ctgaatgggg acatgatgtc
    16501 gcccatgact gggaatggtg gcgtaaacaa atgccttatt tcctcggtaa tctctattta
    16561 taaaaggagt tacctatgaa ttaccttgtt atttctccct actatccaca aaactttcaa
    16621 cagtttacca tcgaactagc taataaaggc atcacagtct tgggaattgg tcaagagtct
    16681 tacgagcaat tggatgagcc cttgcgcaat agcttgaccg agtattttcg tgttgataat
    16741 cttgagaaca tagatgaagt caaacgtgca gttgcttttc tcttttataa acatggtcca
    16801 attggccgca tcgagtctca caatgaatac tggcttgagc tagacgcaac actcagagaa
    16861 caattcaatg tttttggtgc caaaccagag gatctcaaaa agacgaaata taagtctgaa
    16921 atgaagaaac ttttcaaaaa agcaggtgtt cctgtggtac ctggagctgt tatcaagacg
    16981 gaagcagatg ttgatcaagc agtgaaagaa atcggtcttc caatgattgc caaacctgat
    17041 aatggagtgg gagcagccgc aacctttaaa cttgagacag aagacgatat caatcacttc
    17101 aagcaagaat gggaccattc aaccctttat ttctttgaaa aatttgtcac ttccagcgaa
    17161 atctgtacct ttgacgggct cgtggacaag gatggaaaga ttgtcttctc aacaaccttt
    17221 gactacgcct atacaccgct tgacctcatg atttataaga tggacaattc ttattatgtg
    17281 ctcaaggata tggatcctaa actgcgcaag tatggggaag caattgtcaa agaatttggt
    17341 atgaaagaac ggtttttcca tattgagttc ttccgtgagg gggacgatta tattaccatc
    17401 gagtacaata accgccctgc aggtggtttt accattgatg tttataactt tgctcattcc
    17461 ttggaccttt atcgtggcta tgcagctatt gtcgcaggag aggagttccc ggcgtcagac
    17521 tttgaaactc agtattgttt ggctacttct cgccgtgcaa atgctcacta tgtttattca
    17581 gaagaggatt tgcttgccaa atatagccag cagttcaagg ttaaaaaagt catgccagct
    17641 gccttcgcgg aacttcaagg agattacctg tatatgctga ccactccgag tcgacaagaa
    17701 atggagcaga tgattgcaga tttcggacaa cgtcaagaat aagaactatc ggattaagga
    17761 aattaactcc cttaatcctt ttgttttgtc tgataaaaaa taagagcatc ccaacaaggt
    17821 agctatcata aaacttgttc gataactatt tgaagcagga ttaggtggtc agaaattaaa
    17881 ttttaatatt tcaattgagt catagtattg tgtttgcgta tccttaaatc agctaaaagg
    17941 atccatgacg acacctatac gatatagttt tcaagatacc aaacaagtct attaatattc
    18001 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt ttctcaaaac actgttttga
    18061 ggttgtggat agaactgaca gagtcagtat catataccta cggcaaggtg aagctgacgt
    18121 ggtttgaaga gattttcgaa gagtataaaa tattcaggtg acgcatagat atagttaatt
    18181 gaagctttgt ttgaaatctg ataaaataat gatattacta agttttaaaa actaaagaaa
    18241 agggaagata tgattacagg cgaattaaaa aataaaatcg atcagctgtg ggaaattctt
    18301 tggacagaag gaaacgcaaa tcctttaaca aatattgaac agttgactta tctcttattt
    18361 atgaaagatt tggatagtgt cgagcttgga cgtgaaagtg atgctgaatt tctagggatt
    18421 ccttatgagg gagtttttcc aaaagataaa cctgaatacc gttggtcaac ttttaaaaat
    18481 ataggagatg ctcaggaagt ttatcgttta atgactcagg agatttttcc gtttattaaa
    18541 aatctcaagg gggatacaga tgatacagcc ttttcacgat atatgcgaga agctattttt
    18601 caaataaata aacctgctac gcttcaaaag gcaatttcta tcttagatgt ttttccaact
    18661 aggggattag atgtagattt tgataatgac aaacaaagta ttactgatat cggagatatc
    18721 tatgaatatc tgttatcaaa attgtcgacc gcaggtaaaa atggacagtt ccgtacacct
    18781 cgtcacatca tcgatatgat ggttgagttg atgcaaccga ctatcaaaga tatcatctca
    18841 gatcccgcta tgggttctgc tggcttctta gtatctgcta gccgttactt aaagcgtaag
    18901 aaagatgaat gggaaaccaa tacagataat atcaatcatt ttcataatca gatgtttcat
    18961 ggaaatgata cggatacgac tatgttgaga cttggggcga tgaacatgat gctacatgga
    19021 gtagaaaatc cacaaatcag ttaccttgac tcgctgtctc aagataatga agaagccgat
    19081 aaatatactt tggttttagc aaatcctcct tttaagggct cacttgacta caattcaacc
    19141 tctaatgacc ttcttgcaac cgtaaaaacc aaaaaaacag aattactctt tctttctctt
    19201 ttcttgcgaa ctttaaaacc aggtggacga gcagcagtta tcgtacctga tggtgtcctt
    19261 tttggttcgt ctaaagctca taaaggaatt cgtcaggaaa ttgtagagaa tcataagctt
    19321 gatgctgtaa tctcaatgcc tagtggtgtg ttcaagcctt atgctggagt ttcaactgcc
    19381 attctcatct ttacaaaaac tggtaatggt ggtactgaca aagtctggtt ttacgatatg
    19441 aaagcggatg gtttaagttt ggatgataag cgacaaccga ttagcgacaa tgatattcca
    19501 gatattatcg aacgctttca tcatcttgaa aaagaagcag aacgtcagag aacggatcaa
    19561 tctttctttg ttccagttgc tgagataaag gaaaatgatt atgatttgtc tatcaataaa
    19621 tataaagaga ttgagtatga aaaagttgag tatgaaccaa cagaggtcat cttaaagaaa
    19681 atcaatgatt tagaaaaaga aattcaagct ggcttggctg aattagaaaa attactcaag
    19741 tagagaggtg gctgtatgaa aaaagtgaag ttgggggaag tcttatctct aaaaaaaggc
    19801 aagaaagcca ctgtacttgc tgaacaaaca actctaagcc aacgttatat tcaaatagat
    19861 gatttaagaa ataataataa tttaaaattc actgaaagtt taaatatgac tgaagcactc
    19921 ccagatgata ttctgatagc atgggatgga gctaatgcag gaacagttgg ttatggatta
    19981 tcgggagctg ttggtagtac aattacggtc ttaaaaaaga atgagcgata caaagaaaaa
    20041 attatatcag attacttggg agtctttttg gaaagtaaat cgcagtattt acgagaacat
    20101 tcaacaggtg caacaattcc tcatttaaac aagaatatat tacttgattt acaattagaa
    20161 ttgctaggta tcgaagaaca agagaacatt atctgtattc ttaatacgat taaaaggctt
    20221 attactaaaa gaaaattgca gttagatgaa ctaaacttgc tcgt
//
LOCUS       DAVLUM010000040        19074 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLUM010000040 DAVLUM010000000
VERSION     DAVLUM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.040"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            167..1648
                     /locus_tag="VYN42_001290"
     CDS             167..1648
                     /locus_tag="VYN42_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1462358.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2009..3010
                     /locus_tag="VYN42_001291"
     CDS             2009..3010
                     /locus_tag="VYN42_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1462359.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3159..4076
                     /locus_tag="VYN42_001292"
     CDS             3159..4076
                     /locus_tag="VYN42_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1462360.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKVDFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4087..4977
                     /locus_tag="VYN42_001293"
     CDS             4087..4977
                     /locus_tag="VYN42_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1462361.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5006..6622
                     /locus_tag="VYN42_001294"
     CDS             5006..6622
                     /locus_tag="VYN42_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1462362.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6632..7951
                     /locus_tag="VYN42_001295"
     CDS             6632..7951
                     /locus_tag="VYN42_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1462363.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGREHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDNQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8158..8230)
                     /locus_tag="VYN42_001296"
     tRNA            complement(8158..8230)
                     /locus_tag="VYN42_001296"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8195..8197),aa:Lys,seq:ctt)
     gene            complement(8495..9766)
                     /locus_tag="VYN42_001297"
     CDS             complement(8495..9766)
                     /locus_tag="VYN42_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1462364.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10036..10275
                     /locus_tag="VYN42_001298"
     CDS             10036..10275
                     /locus_tag="VYN42_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462365.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10440..10619
                     /locus_tag="VYN42_001299"
     CDS             10440..10619
                     /locus_tag="VYN42_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462366.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10756..10935
                     /locus_tag="VYN42_001300"
     CDS             10756..10935
                     /locus_tag="VYN42_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1462367.1"
                     /translation="MLMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10972..11424
                     /locus_tag="VYN42_001301"
     CDS             10972..11424
                     /locus_tag="VYN42_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1462368.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11715..12185
                     /locus_tag="VYN42_001302"
     CDS             11715..12185
                     /locus_tag="VYN42_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1462369.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPKY"
     gene            12204..13271
                     /locus_tag="VYN42_001303"
     CDS             12204..13271
                     /locus_tag="VYN42_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1462370.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPADITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVVQTHKAMKIARQKMNSSRMLR
                     DEKRYYENWLAELEKELAEGV"
     gene            13273..13701
                     /locus_tag="VYN42_001304"
     CDS             13273..13701
                     /locus_tag="VYN42_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1462371.1"
                     /translation="MEIEISGFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSILFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13836..14789
                     /locus_tag="VYN42_001305"
     CDS             13836..14789
                     /locus_tag="VYN42_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1462372.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDSGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     CMENIHVAAGDLLKGVEIEADVIVANILADILVHLTDDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAELSGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            14791..15534
                     /locus_tag="VYN42_001306"
     CDS             14791..15534
                     /locus_tag="VYN42_001306"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1462373.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELIQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFSADWSVAKWDGKKLDKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15545..17341
                     /gene="pepF"
                     /locus_tag="VYN42_001307"
     CDS             15545..17341
                     /gene="pepF"
                     /locus_tag="VYN42_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1462374.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17587..18141
                     /locus_tag="VYN42_001308"
     CDS             17587..18141
                     /locus_tag="VYN42_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1462375.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            18252..18920
                     /locus_tag="VYN42_001309"
     CDS             18252..18920
                     /locus_tag="VYN42_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1462376.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         5870 a         3292 c         4139 g         5773 t
ORIGIN      
        1 cctcaataga cggtaaaata agaaaattgt ttatatattg tctccgtagt gttattatac
       61 gaaataaaag attttaggaa aagtcgttat atcatgctat acctattctt tgtggtataa
      121 ttgcaagagg tttaatccga taatttataa agagagaaag atattcatga gagatttatt
      181 atctaaaaaa agtcataggc aattagaatt attagaatta ttatttgaac ataaacgttg
      241 gtttcatcgt tctgaactag cagagttatt aaattgtaca gaacgtgcag tcaaagatga
      301 tctatcccat gttaaatctg cttttcctga cttgattttt cattcttcta ctaatggtat
      361 acgcattatt aataccgatg atagtgatat tgaaatggtt taccatcatt tctttaaaca
      421 ttcaactcat ttttcgattt tagaattcat cttctttaat gaaggttgtc aagctgagag
      481 tatttgtaaa gaattttata tcagttcatc ttcgctctat cgtattatta gccaaatcaa
      541 taaagtgatt aaaaggcaat ttcaatttga agtcagtctg acccctgttc aaatcattgg
      601 aaatgagaga gacattcgtt acttttttgc acaatatttt tcagaaaaat attatttcct
      661 agaatggcca tttgaaaatt tttcatcaga gccactatct caattgttag aattggttta
      721 taaggaaaca agctttccaa tgaatttgtc aacgcataga atgctaaagt tgctcctagt
      781 tacgaatcta tatagaataa agtttggtca ttttatggaa gtagataaag attcttttaa
      841 cgaccaaagt ttggattttt taatgcaggc agaaggaata gaaggtgttg ctcagagttt
      901 tgaatcagaa tacaatatct ctttagatga agaagttgtt tgccaattat ttgtgtctta
      961 ctttcaaaaa atgtttttca tagatgaaag tctctttatg aaatgcgtaa aaaaggatag
     1021 ttatgttgaa aaatcttacc atctattgag tgattttatt gatcagattt cagtcaagta
     1081 tcagattgaa atggagaata aggataatct gatttggcat ctgcataata ccgcacatct
     1141 gtatcgtcaa gagttgttta ctgagtttat tttatttgat caaaaaggga atacaatcag
     1201 gaactttcaa aatatttttc caaaatttgt ttcagatata aaaaaagagc tttctcacta
     1261 tttagagact cttgaggttt gttctagttc aatgatggta aatcatctat cttatacctt
     1321 catcactcat accaaacatt tggtgattaa tttgctacaa aatcagccta aactaaaggt
     1381 tttggttatg agtaattttg atcagtatca tgcaaaattc gttgcagaga cactttctta
     1441 ttactgtagc aataattttg aactggaagt ttggaccgaa ttagaattat caaaggaatc
     1501 tttagaagat tcaccttatg atatcattat ttccaatttt attattcctc ctattgaaaa
     1561 taagagactc atctattcaa ataatataaa cacggtctca ctcatatatt tgttaaatgc
     1621 catgatgttt attcgattag atgagtaacc aaaaataaca aaaaaacgct atttcgcgtt
     1681 tgaactgtac ctcaaaagtt agacagaaaa aatctaattt ttggggtgtt tttgttaaga
     1741 aaagaccttc aatcatttaa gcaaaatgta catctagatt tatagccctc taaaactctt
     1801 gtttttttgt agaagatacg aaaaaagcta tgaaaccaag gcttttcctg ttttatgtag
     1861 atgtttacac atgaaaattg aagtattttc aaaagctaat tggagtgatt ttattcatga
     1921 tgggataaat gatctggcca aaaatgactg agaaatagtt gcttaaaaag catttgcatg
     1981 atactatata ttgaaaggag gtgataatat ggtagaacaa agaaaatcaa ttaccatgaa
     2041 agatgttgct ttagaagcag gagttagtgt tggaactgtt tcacgtgtaa ttaataaaga
     2101 aaaaggcatt aaagaagtaa ctttgaaaaa agtggaacaa gcgattaaaa ctttgaatta
     2161 cattccagat tactacgcta gaggaatgaa aaaaaatcga acagaaacga ttgcaatcat
     2221 tgtaccaagt atctggcatc ccttcttttc agaatttgct atgcatgtgg aaaatgaagt
     2281 ctataagaga aataacaaat tactcttatg ttctatcaat ggtacaaata gagagcaaga
     2341 ctatctggag atgttgcgtc ataataaagt tgatggagtg gttgccatta cctatagtcc
     2401 aattgaacat tacttgacgt caggaattcc ctttgttagt attgaccgca catactcaga
     2461 tattgccatt ccttgtgttt catcagataa tgatgcaggt ggaagagaag cagctaaaca
     2521 attaattagt aaaggatgtc agcatttagc ctttgtgggc ggacataata caaccattaa
     2581 tgaaaccaaa cgtcgtagaa tttcatttga aaagtatgtc caagagcata aaatacctct
     2641 tagtattttt gatttggatg agacagttac tgactattat ggaaagctag agagtttctt
     2701 ggaagaaaat tcttctatag atggaatttt tacaatcaac gattttacag ctttggatgt
     2761 gattgaaata ctaaaaaaaa atggcaaacg tattcctcat gatgtccaaa ttattggata
     2821 cgatggaatt aaaatggctg gagatagaga ttatctactt tcaactattg aacaaccatt
     2881 ggaagaaatg gcaaaagaag cggttcgtat tttgtttgat ataattgatg gaaagactgt
     2941 taatttgcag acaatcctac cagtaaaatt tgttgaagga aaaacaacaa aaaatgaaaa
     3001 taagtcttga cagaaagcgc tatcaatgat agaatgaatt cagataaaaa gatttatttt
     3061 taaaacaaaa atgaaacgtt tcaaaaaaga aataaagaga cagcgtcaag cgctatcttt
     3121 tctagaacaa aaatgaaacg tttcaaaagg aggttgctat gaatagcaaa gcgaagcaag
     3181 tttctctttg ggaaagaatc aagaaacaaa aactcttgtt attgatgact gtccctggtt
     3241 tagttttaac ctttatcttt aaatacatcc ctatgtatgg ggttttaatc gcatttaaag
     3301 attacaatcc cttaaaagga attttaggga gtgattggat tggtttttct gagtttacaa
     3361 aattcatatc ctctcccaac tttggtatct tgttagccaa cacattaaaa ttaagtatct
     3421 atggtttatt gcttggcttt ttaccaccaa tcattcttgc tattatgctc aatcaactct
     3481 tgagtgaaaa agtcaaaaaa cgaattcagc tcattttata cgcaccaaac tttatctcag
     3541 tcgttgttat tgtcggtatg attttcctct tcttttcagt gggaggacca atcaacaatt
     3601 ttctttctat gtttggaatg aaggttgact tcttgacaaa tccagacttc tttagacctt
     3661 tatacatctt tagtggtatc tggcaaggaa tgggctgggc ttcaacgctc tacacggcaa
     3721 cattggtaaa tgtagatcca gccttagtag aagcagcccg actggatgga gccaatatct
     3781 tccaacgaat ctggcacatt gatattccag ctcttaagcc tattatggtt atccaatttg
     3841 ttttagctgc aggtggaatt atgaatgtcg gatatgaaaa agcattcttg atgcagacat
     3901 cgttaaattt gccaacttct gaaattatct cgacatatgt ctataaagtt ggtcttgtat
     3961 caggagacta ttcttactca acagcggttg gtttgtttaa tgcagtgatt aacgtagtat
     4021 tgcttgttgc agttaaccaa atcgttaaac gcatgaataa tggtgaagga atttaaggag
     4081 gaaagtatga aaaattcgat tatggataca aaatttgata gacgtatctt actcttaaat
     4141 aaaatcatta ttgtctttat cgttttgatg actttgcttc ctttacttta tatcgtcgta
     4201 gcatccttta tggatcctaa ggttctggtt agtagaggga ttagctttaa tccagccgat
     4261 tggactgtag aaggttacca gcgtgtattc agtgaccaat ctattctaag aggttttatc
     4321 aattctctac tatactcttt tggatttgca gctttaacag tcttgctatc tgtgtttaca
     4381 gcttatcctc tttctaagaa agacttggtt ggacgtcgtt ggattaacta cttcttgatt
     4441 gtaactatgt tctttggtgg tggtttagtc ccaacttact tgctcgtaaa agaattggga
     4501 atgctcaata ctccatgggc tatcattgtt ccaggtgctg tcaatgtttg gaatattatt
     4561 cttgctaggg cctatttcca aggattgcct gaagaattag ttgaagctgc tgtcattgat
     4621 ggtgcaaatg atttacagat tttctttaaa atcatgcttc ctcttgcaaa accaattatg
     4681 tttgttctct tcctctatgc ttttgtagga cagtggaact catactttga tgcaatgatt
     4741 tatatcaagg atccaaactt ggaaccattg caacttgtac ttcgtaaaat tctcattcag
     4801 agccaaccag gtcaagacat gattggagca caagcggcta tgaatgaaat gaaacgttta
     4861 gctgaattga ttaaatacgc aactattgtc atttccagct tgccattgat tgttatgtat
     4921 ccattcttcc aaaaatactt tgataaagga attatggctg gttcacttaa aggataaaaa
     4981 aagaaaaaat aaaaggagtt ttctcatgaa attcaaaaca ttctcaaaat cagcagtttt
     5041 gttgacagct agtttagcag tacttgcagc ctgtggctca aaaaatacag cttcaagtcc
     5101 agattataag ttggaaggtg taacattccc gcttcaagaa aagaaaacat tgaagtttat
     5161 gacagccagt tcaccgttat ctcctaaaga cccaaatgaa aagttaattt tgcaacgttt
     5221 ggagaaggaa actggcgttc atattgactg gaccaactac caatccgact ttgcagaaaa
     5281 acgtaacttg gatatttcta gtggtgattt accagatgct atccacaacg acggagcttc
     5341 agatgtggac ttgatgaact gggctaaaaa aggtgttatt attccagttg aagatttgat
     5401 tgataaatac atgccaaatc ttaagaaaat tttggatgag aaaccagagt acaaggcctt
     5461 gatgacagca cctgatgggc acatttactc attcccatgg attgaagagc ttggagatgg
     5521 taaagagtct attcacagcg tcaacgatat ggcttggatt aacaaagatt ggcttaagaa
     5581 acttggtctt gaaatgccaa aaactactga tgatttgatt aaagtcctag aagctttcaa
     5641 aaacggggat ccaaatggaa atggagaggc tgatgaaatt ccattttcat ttattagtgg
     5701 taacggaaac gaagatttta aattcctatt tgctgcattt ggtatagggg ataacgatga
     5761 tcatttagta gtaggaaatg atggcaaagt tgacttcaca gcagataacg ataactataa
     5821 agaaggtgtc aaatttatcc gtcaattgca agaaaaaggc ctgattgata aagaagcttt
     5881 cgaacatgat tggaatagtt acattgctaa aggtcatgat cagaaatttg gtgtttactt
     5941 tacatgggat aagaataatg ttactggaag taacgaaagt tatgatgttt taccagtact
     6001 tgctggacca agtggtcaaa aacacgtagc tcgtacaaac ggtatgggat ttgcacgtga
     6061 caagatggtt attaccagtg taaacaaaaa cctagaattg acagctaaat ggattgatgc
     6121 acaatacgct ccactccaat ctgtgcaaaa taactgggga acttacggag atgacaaaca
     6181 acaaaacatc tttgaattgg atcaagcgtc aaatagtcta aaacacttac cactaaacgg
     6241 aactgcacca gcagaacttc gtcaaaagac tgaagtagga ggaccactag ctatcctaga
     6301 ttcatactat ggtaaagtaa caaccatgcc tgatgatgcc aaatggcgtt tggatcttat
     6361 caaagaatat tatgttcctt acatgagcaa tgacaataac tatccaagag tctttatgac
     6421 acaggaagat ttggacaaaa ttgcccatat cgaagcagat atgaatgact atatctaccg
     6481 taaacgtgct gaatggattg taaatggcaa tattgatact gagtgggatg attacaagaa
     6541 agaacttgaa aaatacggac tttctgatta cctcgctatt aaacaaaaat actacgacca
     6601 ataccaagca aacaaaaact agaggttgat tatgggagat aagaaataca cagtagaaaa
     6661 agccaatcgt tttatagcag aaaataaaca tctcgttaat actcaatata agcctgaaga
     6721 acatttttca gctgagattg gttggatcaa tgatccaaat ggatttgtct attttcgtgg
     6781 agaataccat ctcttttatc aattctatcc atatgatagt gtttgggggc ctatgcactg
     6841 gggacatgct aaaagtaagg acttggtgac ttgggagcac ttgccagtgg cacttgctcc
     6901 tgaccaagat tatgaccgaa atggttgttt ctcaggctct gccattgtca aggatgatcg
     6961 cctctggctc atgtacactg gacatatcga agaagaaacc ggtgtccgcc aagtgcaaaa
     7021 tatggcattt tcagatgacg ggattcactt tgaaaagatt tcccaaaatc cagttgcaac
     7081 tggatcagac ttgccagatg agttgattgc tgctgatttc cgtgatccaa aactctttga
     7141 aaaagatgga cgctattact ccgtagtagc taccaaacac aaggataatg tgggctgtat
     7201 cgttctacta gggtccgata acctagtaga atggcagttc gaatccatct ttttaaaagg
     7261 gagagaacac caaggcttta tgtgggaatg cccagattac ttcgagttag atgggaaaga
     7321 ttgccttatt atgtcaccca tgcgttatca gcgtgaggga gactcatatc ataacatcaa
     7381 ctcatcgctt ttgttcacgg gtaaggtaga ttggggagaa aaacgtttta tcccagaatc
     7441 agttcaagaa atcgatcatg gccaagactt ctatgcgcct caaacattgt tggacaatca
     7501 aaatcgtcgt atcctgattg cttggatgca gacatggggg cgtacccttc caacccatga
     7561 ccaagaacac aaatgggcat gtgccatgac tttacctaga attctaagat tggaagatgg
     7621 caaactaaga caattccctg ttaaaaaagg ccaatatcaa atccaaatag ataaagattg
     7681 tcattaccac ttaggaaatg atatagatta tcttgaattt ggttatgaca gtaatgcgca
     7741 gcaagtttac attgatcgta gccatcttat tcaaaaaatt ctaggtgaag aagaacagga
     7801 cactagtcga cggtatgtag atattgaagc taaagaattg gaagttgttc tagataaaaa
     7861 ttccatcgag atttttgtca atcaaggtga agcaagcttg actgcaactt attacttaac
     7921 ggtgccagct gagctatcac gaattgatta aaaattaagt tatttctcct aaagaaaaag
     7981 ttctctttct aaaatagtgg aaagaggact ttttgtgttt tgggtatata agcttagttt
     8041 atggtatttg taaaattggt gttggattat gatttaagct agttttctaa agaatttgaa
     8101 aaaattttat ttaagcaaaa aaaccttggt tccaaggctt ttcctgttgt atttatatgc
     8161 cccctacagg gatcgaacct gtgacccacg gattaagagt ccgctgctct gccagctgag
     8221 ctaaggaggc aaagaaaaaa gctgtattgg tgccgaaact tcacggtttg tattgaaccc
     8281 gcgcaattaa gcaggtgggc aactcgctct aactgaagct gtttccgtgt gagacggcct
     8341 acatgctgtt agaagacttt tgtttcccta ataatacaaa aaatagtcgg tcaacactta
     8401 agtgtgaagt cgtacaccac agcgtttcta tacttatatg ataccacttt ttcaaaaaaa
     8461 atcaagagga aagtgcaatt ttttgaaaag gatttcagat ttttcgcaaa cggtcgatag
     8521 cttcctttct ttgagccaaa gcccgttcat atttaccagt atcttctgct tggaaatagt
     8581 gatgattacg aattttttct ggcagatagt cttgcttgac ccaatttcca ggatagttgt
     8641 gtggatagag atagtcttgg gcattcccca gttccttgct tccactgtag tgcccatcac
     8701 gcaggtgtcg cggaataggc aagtgccctg atgttttgag gtcagcaagt gccttatcca
     8761 tagctacata ggctgagttg gattttggag aaagggccaa atcaatcacg acattggcaa
     8821 tgagaatgcg ggcttcgggg aaaccaatcc tttgtgcagc atccagagca gtcacggtat
     8881 gaatctgggc ctcaggattg gctaagccga tatcttcata ggcgataaca gtcaagcgac
     8941 gagcgagact aggcagatcc ccagcctcaa tcaagcgggc agtatagtgg agactggcat
     9001 ccacatctga gccacgaata gacttttgca gggcagatag aacatcatag tgaccgtctc
     9061 catccttgtc catagtgatg tagcttctct gaagactatt ttccatgatg tctaaggtga
     9121 tgtggcgaat gccctcgtca ttctcagggg tagagagaac agccaagtcc agtgagttaa
     9181 aggcagagcg aaggtctccg tttgtagagg ttgcgatgaa atccagcgca tcctcatcta
     9241 gttctattgg aaaatcaaaa ccacgttcag ggttacttag agctatctgc agggcctctt
     9301 tgacgtcttg gttagacaga ggttccaact cgaaaatttg aacacggcta cgaatggcag
     9361 gagtgacaga gaagaaagga ttttcagtcg ttgctccaat catgatgacc agtccacttt
     9421 ccaagagagg caagaggaag tcttgcttgg tcttatctag tcgatgaatt tcgtctagca
     9481 ataggacgag accaccagaa aatttagctt cttccgagat ttcttgcagt cgctttttac
     9541 tatcaactgt cgcattgaaa gttcgaaagg catacttggt cgttccagcg atggcagagg
     9601 caatactggt tttgccgatt ccaggagggc catatagaat catggaggac aggcggttgg
     9661 cttccaccat gcggcggatg atttttccag gtccgaccag atgctcctga ccgatgacct
     9721 ggtcgatggt tttagggcgc atgcgaagcg cgagattgtc tggcatagca gtcctttcta
     9781 acgtggattt gagtagaatg actcatctac tatatcttac tatgtccatt ctagcctatt
     9841 agttgtgata tttcaatggt tttgtaataa tcagggagtg agatagaatc ttttttacta
     9901 tttaatttaa tgaggagagg tatcagcatg agagatttga ttttccttaa agctcaaaat
     9961 aggatagttg agcctaaaga agtggaagtg ctgacttgag aaataatatt gctgaatgtc
    10021 attgtatgaa ctataatgaa aagagaggtg ataagcaatg gaaatgatgg accaagtcag
    10081 gaaattttga tttttacaaa acaaattcgt cattggattc ttagtgatca agttatttca
    10141 gggaaaagaa aacttttctt ccgggaagat actccaaaag agattttaga tttgtacgaa
    10201 aacattaaat ctaaacttga ttttgcttac caagaagttc attctaataa tgggttgaaa
    10261 aaatatgaaa aatagaataa ttgatgtttt tgaagtagta aatcgcctcc ttgtaataac
    10321 tgttgaaaat cctgatttcg aagacttgag agttaatcat actcaatgaa aatcaaagag
    10381 caaactagga aactagccgc aggctgtact tgagtacggt aaggcgacgt tgacgtggtt
    10441 tgaatttgat tttcgaagag tatcagtttg taaaaattgg agataaaaaa tatagagtac
    10501 gcagtgttcc tatgattcat tcaactccgc ctcaatctgt cttagatcga gatactttta
    10561 caattgacta tacagatgat gaattgctcg ataaagaagc agtttttact actcattaga
    10621 aaaataggtc tgaataaatt ggcttccctt agaaccacat ctaggggctt ttatgtataa
    10681 tagaataata agtatcactc ctttacaata cgtgtaacac gtgttataat ggtgttgtca
    10741 ggaggtaaaa gcgctatgct tatgacacaa aaagagatgg ttaaactcct tacggcccat
    10801 ggttggataa agactagagg cggtaaaggc tcccatatta aaatggagaa gcaaggggaa
    10861 agacttatca caatccctca tggtgagctg aataagtaca ctgaaagagg gataagaaag
    10921 caagctgggt tgtaaaattc agcccctgtt ttttgatatg gaggtagtga aatgttagtt
    10981 acgtatccag ctttatttta ttatgacgac acagacggaa cagaagcgac ttattttgtc
    11041 catttcccag attttgaata ctcagctaca caaggagagg ggatttctga ggctttggct
    11101 atggggtcgg agtggctagg gataactgtt gcagatttga tagagagtga tggagagtta
    11161 cctcagccat cagatatcaa tagcttgtct ttaattgata atgatccttt taaagatgat
    11221 gaagatttcg tgtcaaccta tgaccttgat aaatctttta tttctatggt atctgttgat
    11281 gtatcagaat acctaggaag tcaggaaccc attaaaaaga ctttgaccat accaaaatgg
    11341 gcagataagt tgggacgaga aatgggactt aacttttctc agactttgac agacgctatt
    11401 gcagataaga aagttcaagc ctaagattaa gcgtggtatc gtggtaatag tcaataaaaa
    11461 agcacgtcca cttgtgctaa ttactcgcct attgatttta tagatttatt agccctttcg
    11521 agggcttttt atattgattt ttatgagaaa tgaagaaatc agacttttaa gaaaatcact
    11581 gataccaagg gtttaaatga ggtaatatgg tataattagg acataaaata attttgtggt
    11641 aagatggtag tatctatttt agcatatttc cgagcaatcg gggcgattaa agagtcgcat
    11701 agaaagagga caaaatggca acatacggat ttttagatgt tttagaggaa gagttggaca
    11761 agaactttcc ctttgacttt gagattagct gggacaaacg caaccatgcg gtagaagtga
    11821 gttttctatt ggaagcgcaa aatgctgcag gtgtggagat ggtggatgaa gacggagagg
    11881 tttcatcaga tgacattctt tttgaggaag cggtcctttt ctacaatcct gccaagtcaa
    11941 cagtcaatga ggaagactat ttgactgtta ttccttacct gcctaaaaaa ggattttccc
    12001 gtgaattttt agcttatttt gcgcttttcc ttaaagatac tgctgaggtt gggctagatg
    12061 tcctcatgga ctttttggaa gacccagaag cagaggaatt tgttatggaa tggaaccaag
    12121 aagtctttga agaaggaaaa gttggcttgg aagagggaga attttatcct tatccaaaat
    12181 actaggagtt ggttggaggt gttatgaaga aaattgggac ttatttggtt tatgtgctag
    12241 ctgttgtctt tattatgcta gcttttgctt gtggaacaat cgcatttgca gagttggggt
    12301 attccgcagt tttagccttt acttttggtt atgccttcgc tcttctaagc atgtatttaa
    12361 tctttattct tcatgagctg ggtcatgctt tttgtggcta cttgacaggc tatcggctgg
    12421 tggcttttgg attaggacat tttattttga ccaaaaagtc aggcaggttt catcttagta
    12481 gaacagccat tctgaaaaat gttggtgctc aatacattgg tttaaaagag gatgaaagcg
    12541 atcaaagaat catcctgatg ctttcaggag gcttgatggt tcatctcggc ttgatattat
    12601 tggcgatatt gtttggattt ttgacaagaa gctggtattt tgcagggact tggatttttc
    12661 ttaatttatc tttcttccta aataacattt tgccagccga catcaccgat ggagcaaaaa
    12721 tttgggaatt actacaacac cctgaaaata ccaaatacgc ctacctggta ttgagacatt
    12781 ctgctcaaac tttgctggct cctcaagaat atgatttgaa agactttgtt caagcagttc
    12841 ctgaggatgc acgagggagt tttgcggatg gtgtattagg tatgcaaggt gaagtttcca
    12901 ttttggaagg gaaggaagaa gtagctaaac agcagtttca agcattactt gagaggacaa
    12961 ctactccgat gatgcagaca gttgcccaac tatccctgct tcatatcgcc ttgttggaag
    13021 gagattttga gcaagcggag caatatgcta gtattcgaca ggtcaaatcg tttctgtctc
    13081 tcaaactgtc caatcttcaa gtgatacaag cttggtatca atttaaggta aagaaagatg
    13141 tagttcaaac tcacaaggct atgaagattg ctagacagaa aatgaatagc agccggatgt
    13201 tacgggatga gaaaagatat tatgaaaact ggttagccga gctggaaaag gaattagccg
    13261 aaggagtcta atatggaaat agagatttct ggtttcacag gttgcaagat tgctttgttt
    13321 tgtggggata agcttttgac tatcttacgc gatgataagg caagcattcc ctgggccaat
    13381 atgtgggaac tgccaggtgg tggacgtgaa ggtgatgaaa gtccttttga gtgcgcggcg
    13441 cgtgaagttt atgaagaact gggcattcat ctgactgaag attgtctgct ttggagtaag
    13501 gtttacccaa gtatactttt tgcagacaaa cagtccgttt ttctagttgg tcagttgaca
    13561 cagaaccagt ttgacagtat cgtatttgga gatgaaggac agggctatca gctgatgaat
    13621 gttgaggaat ttcttagttc cagtcaagtt gtgcctcagt tgcaagagag attaaaagat
    13681 tatttaaaag taagtgatta gaaaggatgg ttcagttaaa tttctaaact gaacccgccc
    13741 taaatactgt gccaaaaaga taaacttctc ttagacacaa gcgtcttcag agaatttcct
    13801 attttggttt tgtgttttac gggcttggta tcttaatgat ggaaacatgg caagagttaa
    13861 aagttacagt gaagcgtgag ggagaggagt tggtttccaa tctcttgatt gagctgggag
    13921 cgcaaggtgt tgcgattgaa gacagcatgg actatgtggg aaatgtggat cgctttggcg
    13981 agattttccc agaggtggag cagcaagaag aaatcgtagt gacagcctac taccctgaca
    14041 cggtggatgt gacagtggtt gaggcggact tgcaggctcg catatcagaa ttgacggatt
    14101 ttatggattc gggagagtta aaaataggta cgactgcctt ggctgaggaa gactgggcag
    14161 acaactggaa gaaatactat gagccagctc gtatcactca tgatttgacc atcgttccct
    14221 cttggacaga ctatgaggcg actgcgggag aaaaaattat caagctggat cctggcatgg
    14281 cttttggtac tggaacccac ccaactacca agatgagcct ttttgccttg gaacaggttc
    14341 ttcgtggtgg cgaaacggtg ctagatgtgg ggactggttc aggggttctc tctattgcca
    14401 gctcgcttct gggggctaaa gaaattttcg cctatgacct ggatgatgtg gcggttcgtg
    14461 tggctcagga aaatattgag ctcaaccctt gtatggaaaa catccatgta gcagcaggag
    14521 acttgcttaa gggtgttgag attgaggcag atgtgattgt agctaatatc ttggcggata
    14581 tcctcgttca tctgacagac gatgcctatc gtttggttaa ggacgaaggc tacctgatca
    14641 tgagtgggat tatcaaggac aagtgggaca tggtgcgcga gtcggctgag ttatctggat
    14701 ttttccttga gacccacatg attcaggggg aatggaatgc ctgtgtcttc aagaagacca
    14761 aggatatctc tggtgtgatt ggaggctagc atgcagcagt attttgtaaa aggcagtgct
    14821 atctctcctg tcactatcga ggacaaggaa accagtaagc atatgtttca ggttatgcgc
    14881 ttgaaagaag aggatgaggt taccttagtc tttgatgatg gcatcaagcg cttggcgcgc
    14941 gtgctggata tggaaaatcg tcagtttgag ttgatccaag aattaaatga caatgtggaa
    15001 ctaccagtcc aagtgaccat cgcatctgga tttcccaagg gagacaagct ggagttcatc
    15061 gctcaaaaag taaccgaact gggtgctagc caaatctggg ccttttctgc agattggtca
    15121 gttgccaagt gggatggcaa gaaattggat aaaaaagttg aaaaactaga aaaaattgcc
    15181 cttggagcag ccgagcaaag caagcgtaat attgtaccaa gtattaaact tttcgagaaa
    15241 aaagcagatt ttctagctca gctggaccag tttgactcta tcatagtagc ctatgaagaa
    15301 tcagctaaag aaggagaagc cgctgcgctt ctgcaagcag tcactggtct tgaaacagga
    15361 gccaaactgc tctttatctt tggtccagaa ggcggtctct cacctgcaga aatcgaaagt
    15421 tttgaagcta aaggagccgt tttggcaggc ctaggtcctc gtattttgcg agcagaaaca
    15481 gcaccgcttt acgctttatc agcccttagt gttttagtag aattagagaa ataagaggaa
    15541 gaaaatggaa caaaaacacc gttcagaatt tccagagaag gaactctggg acttaacagc
    15601 cctataccaa gaccgtgagg atttcttgcg tgcaatcgag aaagctcgcg aagacatcaa
    15661 ccagtttagc cgtgattaca agggcaacct tcacactttt gaggatttcg agaaggcctt
    15721 tgcggaattg gaacagatct acattcagat gagccatatt ggcaactatg gttttatgcc
    15781 tcagacgacg gactatagca atgacgaatt tgccaatatt gcccaagctg ggatggaatt
    15841 tgaaacagat gccagcgtag ccttgacctt ctttgacgat gccttggtgg cagcagatga
    15901 ggaagtcttg gaccgtttgg gtaaattgcc acatttaaca gctgccattc gtcaggctaa
    15961 aatcaaaaaa gcccactact taggggcaga tgtggagaag gccttgacaa atctcggtga
    16021 agttttctac agtccgcagg acatttatac taagatgcga gctggggatt ttgaaatggc
    16081 tgactttgaa gcccatggca agacctacaa aaacagcttt gtgacctatg agaatttcta
    16141 ccaaaaccat gaggatgctg aggttcgtga gaaatccttc cgttccttct cagagggact
    16201 tcgtaagcac caaaatacgg ctgcagcagc ctatctggct caggtcaagt ctgaaaaact
    16261 cttggctgat atgaagggat acgactctgt ctttgattat cttctagctg aacaagaagt
    16321 ggaccgtgtc atgtttgacc gccagattga cctcatcatg aaggactttg caccagtcgc
    16381 tcagagatac ctcaagcatg ttgccaaggt aaatggtctt gaaaagatga cctttgcaga
    16441 ctggaaattg gacttggaca gcgccctgaa tcctgaagtg actattgacg atgcctatga
    16501 tttggtcatg aagtcggtag aacctttggg gcaagaatat tgtcaggaag ttgctcgtta
    16561 ccaagaagag cgctgggtgg actttgctgc taacagtggc aaggattccg gtggttatgc
    16621 ggcggaccca tatcgcgtac acccttatgt cctcatgagc tggacaggcc gtttgagcga
    16681 tgtctatacc ttgattcatg aaatcgggca ttctggtcaa ttcatctttt cagacaatca
    16741 tcaaagttac ttcaatgccc atatgtcgac ctactatgtt gaagcaccgt caaccttcaa
    16801 tgaattgcta ctcagtgatt acttagagaa ccaatctaat gacccacgtc aaaaacgctt
    16861 cgctctggct catcgcttga cagacaccta cttccataac tttatcaccc acctcttgga
    16921 agccgccttc cagcgtaagg tgtatacatt gattgaagaa ggagaaacct tcggagcaag
    16981 caaactcaac agtattatga aggaagtttt gacagatttt tggggcgatg ccattgaaat
    17041 cgacgacgat gcagctttga cttggatgcg ccaagctcac tactatatgg gcttgtatag
    17101 ttacacttac tctgctggtc ttgtcatctc gacagctggt taccttcatc ttaaaaactc
    17161 agaaactgga gctgaagact ggctcaatct cctcaaatca ggtggtagca agacaccact
    17221 tgagtcagcc atgattatcg gtgctgatat ttcaacagac aaaccactcc gtgataccat
    17281 ccaattcttg tctgacacag ttgaccagat tatcgcctac agtgctgagt tgggggagta
    17341 aggagataga aaaatttttt agaatgatgt ttatgggctt gttaagcgtc attctatttg
    17401 tcttagttgt agctattttc aaaaatgtcg ttgaaggtcg tgatgttaaa tttgaactta
    17461 ctgtagaact ggtattgata gttatttacg tcattttata tcagattgta tttaattgag
    17521 aattcaatat tgagtcattt aagactgcct ttttgaacag ttgctagaaa tgtagaggta
    17581 ttgaccatgt atcaagattt actaagaaaa atagcagaag aaaaaccaaa ttataaccag
    17641 gaagaaatcc agtggttgtt tgatcatttg ggaaatcctt ctccagaaat tcgtaatgtc
    17701 cttttaaatc aaggcttgca ctatctttca aaagaaaagg atacaacagg tttctcaagt
    17761 cagtatggtt gggttcatgc ttttgcacat ggagccgatt tactgacaga ggtggtttgt
    17821 catccagact ttcctataaa cagaattcat gaagtatttg acatacttgg ccaactattt
    17881 aaaagaatgt cgattcgctt tacagatgat gaggattggc gtttagcaag agtgatctat
    17941 gaacctattt tacaagggaa gttggagcaa gaacaagtag cttcttggat aaaaactgtt
    18001 gattttccga tagaagaaag ggaggatttt tacaaatttt ccaactttag atcctgtctg
    18061 gtggaagtct atgtccaact tgaccagaga aatagtttac aagatgagtt gaaagaagct
    18121 atccagtctt ttcaatacta gagattagct aatagttcta tgattttcaa aaaatttcca
    18181 atcaattttc ttgaaaccct ttcctacttt tgatagacta gtatctagtt tttgaaaaaa
    18241 ggagaaagaa aatgaaaaaa tttgttgctg agttaatcgg tacgttcatg cttgtattcg
    18301 tcgggacagg agctgttgtt tttggaaatg gtcttgatgg ccttggtcac cttggaatcg
    18361 cctttgcctt tggtttggca atcgtggtgg cagcctactc aatcggaact gtttcaggtg
    18421 ctcacttgaa cccggctgtt tcgattgcta tgtttgtaaa caaacgtttg tcatcttcag
    18481 aacttgtaaa ctacatcctt ggtcaggttg ttggagcttt catcgcttct ggcgctgtct
    18541 tcttcctctt ggctaactca ggtatgtcaa ctgctagtct tggtgaaaat gccttggcaa
    18601 acggtgtcac tgtctttggt ggtttcttgt ttgaagtcat cgcaactttc ttgtttgtat
    18661 tggttatcat gactgtgact tcagaaagca agggcaatgg cccgattgct ggtttggtaa
    18721 tcggtttgtc attgatggcg atgattcttg tcggattgaa gattactgga ctttcagtaa
    18781 acccagctcg tagcttggca ccagctgtct tggtaggcgg cgcagccctt caacaagttt
    18841 ggattttcat ccttgcacca atcgctggtg gagttcttgc agcccttgtt gcaaaaaatt
    18901 tccttggaac agaagaataa ttgaaactca aaaagccttg ctcctcatct tgaggaacag
    18961 ggctttttcg tatgatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgccg
    19021 taggtatggt tactgacttc gtcagtttca tctacaatct caaaacagtg tttt
//
LOCUS       DAVLUM010000041        18470 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLUM010000041 DAVLUM010000000
VERSION     DAVLUM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.041"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            248..568
                     /locus_tag="VYN42_001310"
     CDS             248..568
                     /locus_tag="VYN42_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1462377.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETYYQ
                     PKER"
     gene            complement(1071..1451)
                     /locus_tag="VYN42_001311"
     CDS             complement(1071..1451)
                     /locus_tag="VYN42_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV1462378.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(1597..2949)
                     /locus_tag="VYN42_001312"
     CDS             complement(1597..2949)
                     /locus_tag="VYN42_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEV1462379.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQTLQNELIQLQQQGDSSSLSDTTSDDDKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLISEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILASNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKVDVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVILQKDMPVEVQIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(2946..3413)
                     /locus_tag="VYN42_001313"
     CDS             complement(2946..3413)
                     /locus_tag="VYN42_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1462380.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINRFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(3406..5625)
                     /locus_tag="VYN42_001314"
     CDS             complement(3406..5625)
                     /locus_tag="VYN42_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV1462381.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            6091..6954
                     /locus_tag="VYN42_001315"
     CDS             6091..6954
                     /locus_tag="VYN42_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462382.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(7006..7593)
                     /locus_tag="VYN42_001316"
     CDS             complement(7006..7593)
                     /locus_tag="VYN42_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1462383.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            7835..8506
                     /gene="sdaAB"
                     /locus_tag="VYN42_001317"
     CDS             7835..8506
                     /gene="sdaAB"
                     /locus_tag="VYN42_001317"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1462384.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            8515..9387
                     /gene="sdaAA"
                     /locus_tag="VYN42_001318"
     CDS             8515..9387
                     /gene="sdaAA"
                     /locus_tag="VYN42_001318"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1462385.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            9409..10041
                     /locus_tag="VYN42_001319"
     CDS             9409..10041
                     /locus_tag="VYN42_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1462386.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEALQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            10091..10258
                     /locus_tag="VYN42_001320"
     CDS             10091..10258
                     /locus_tag="VYN42_001320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462387.1"
                     /translation="MKIKEQTRKLAAGSSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIRQGDVDVV"
     gene            complement(10343..12193)
                     /locus_tag="VYN42_001321"
     CDS             complement(10343..12193)
                     /locus_tag="VYN42_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1462388.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(12235..13392)
                     /locus_tag="VYN42_001322"
     CDS             complement(12235..13392)
                     /locus_tag="VYN42_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1462389.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAISTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            13450..14616
                     /locus_tag="VYN42_001323"
     CDS             13450..14616
                     /locus_tag="VYN42_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1462390.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            14755..15081
                     /locus_tag="VYN42_001324"
     CDS             14755..15081
                     /locus_tag="VYN42_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1462391.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            15068..15661
                     /locus_tag="VYN42_001325"
     CDS             15068..15661
                     /locus_tag="VYN42_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1462392.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            15654..16565
                     /locus_tag="VYN42_001326"
     CDS             15654..16565
                     /locus_tag="VYN42_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1462393.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            16627..17691
                     /locus_tag="VYN42_001327"
     CDS             16627..17691
                     /locus_tag="VYN42_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462394.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(17928..18125)
                     /locus_tag="VYN42_001328"
     CDS             complement(17928..18125)
                     /locus_tag="VYN42_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding protein"
                     /protein_id="HEV1462395.1"
                     /translation="MRSLSQEKDIYSFDEPTGNLDRNSTELFLNEVEKLVNEEKIVIV
                     VTHDKDVIARASKVINMDEFH"
BASE COUNT         5737 a         3916 c         3064 g         5753 t
ORIGIN      
        1 aaaattacgt taactttttt cacgaaaagg agaaaattat gcgttatgat tatggatagc
       61 gctttcaaat ttttaaactc ctatcccatc cttttatcta tattatgagc gaaaatataa
      121 taactgtcaa gtaactaaag tgaattttat aaaaaaatta caagccaaat ttgtaaagtt
      181 tacactaagc cgctagggca atcgtctatc agaatgtccg tttatttgtc aataatccga
      241 gaaaatcttg caacgcttag aagtctataa aaactatcaa catttatatg acttgcgaat
      301 agcaatcctg ctcaaccttt ccacactcta tctatacaat caagataaaa acatgtgtaa
      361 gcaaatctgc tacactttac tagaggacgc caagaataag aaaagctacg ataggctggc
      421 tatctgctat gtccgtattg ggatttgtac agacgattct aaacttatcc aaaaagggtt
      481 ctcccttctg gagctaaccg aggaaacttc tatgctgtct catctcaaaa aagaagtaga
      541 aacctattat caaccgaagg aaagataaaa aagccgaggg atttcctcga ctctttacat
      601 attatttgtt cgttagttct taataccagc cattgttaaa ccagaagttt ttagctctgc
      661 caagccacat agtgtgttta ctactatgtg tccatgtcac catgaatcgc cgaacgattt
      721 aacgagaaag tatgactttt acgtttatcc caactcaatt atgacatttt tttcaaaagt
      781 caatatatct cactttttca acgacaagaa agaggctgat aatctaccaa cctcttgttt
      841 ttaaatacat ttcaagtcca aactattctt tatagaaaaa agtcctataa attcgagcaa
      901 tagttaaaat acaaacaaat ataattccca aaatagataa cactattttc acaaaattca
      961 tttcagaacc tattatatat acgtgaaaaa aaggggctat tcctacacat atatacaata
     1021 aataacttac aaagtttatt tcaccaattc ctgcaaaaaa atgtttcatt ttaagcaaaa
     1081 atataaccat ctaagctacc gtcagcccaa tcagccccat atgcgattgc tccacctagt
     1141 gaaaatccag taacagttag tgcaacgttt agtgcagtat tgactaaatg gccagctgca
     1201 ctacctacat gtttaattat taaactacgt aatgttctcg taatagcccc tctattagct
     1261 gagatagctt tttttatcgc ataagcagaa taaattgttg caccaccact atagatggcc
     1321 aaacctacat ccagaactgt tgcaaaacta cctctactat tccaccagtt acgaccaaca
     1381 ccacccccat caagatacat catctcttct tgctcaagag caacataatt atttggtaat
     1441 acgagttcca tttattttct ccttttttat taagcatggt taggatagtt tcctaacaag
     1501 tgagcatcga ctttgtttat agcacttagt tacctagata agatatcttc cctttatctt
     1561 actttatttt ataggtgact taatgtttaa aaccaattat tgcttgaaac ttaacatttc
     1621 caaaatccaa tcaagatagg tttctttatc atagacaatc tgcacttcaa ctggcatatc
     1681 cttttggagt atgaccgtct cgcttccatg ttttagagtt aaggtttcta attctatcat
     1741 gactttatag aggctaatat tcccctcttt cgtttcttgg gaaattgttc ctgaatcaat
     1801 ctgtctgact tgtcccttta gtgttccata tttttgacta tttacaccag taatagcaac
     1861 atcaactttt gctccttttg agacacgaga aatatcactc gcaagtacaa aagcctctac
     1921 atagtaacct ttttctttcc ctgaaacttc tgctatcgtt tgcccctgct gaatagacat
     1981 tccttgtttc aaaggtacca gataatgcag agtaccttca tttgacgcta atatactatg
     2041 agctttatct tgacctgttg ccactccaag attagcctca agctctgtaa tacttttatt
     2101 gttgtttgaa cgagcagtac ctaactcact aattaattga gcataaatat tataagcctg
     2161 agaagttgga tcattatagg tacggttcat atccttaata ttgctttgtt gactatcaat
     2221 ctcgctattc ttagaagtaa tatttgtttt taatgcttcg atttttgttg ttatttctga
     2281 tatcttagtt tctaacttag ctttatcatc atctgatgtc gtatctgata aggaggatga
     2341 gtctccttgc tgttgaagtt gaatcaattc attttgtaga gtttgcaagt cggcatctaa
     2401 ctgatttctt tcagctgtta ttttattcaa cttcgtatat tcatcctgaa tctttgaata
     2461 ctgggtacca ttattataat tttccgagtt taactgagac agatagtatt caactttccc
     2521 ataatattcc tgttcttcac cagaattaga taaatgattg tatttctcat ttaatgattg
     2581 ttcaaatttt tgaaagatag cttcttttgc acgtaacttc tccaattgtt tatttaaaga
     2641 gctcgcttgt aaaccttctt gtccacttga taacgaaata atgacatctc cagcatttac
     2701 catatctcct tctgacttat gtaaagtaac taccttccct gaaccaattg ctgataggaa
     2761 ctctgtacct gttataactg aatttccatt cgcttttaca atatagtttt tgggtatata
     2821 agctgcgcca accaatgcac cgcttaagat aatagcagtt gaaataatga gaataaacgc
     2881 aaaagctggt ggtctcttat caaagaaaat acgagaataa cgtaattctg atttattata
     2941 taatttcata ggcttacaat tggtctaaaa atatctacta ccattttttc aggagaagaa
     3001 ttaacataaa ctgtatagac aatcccatcc gtttgaatat cattttcata gacatataga
     3061 tccaatttag aatacgcata ctgtagatac tctggactgt cttcaaaacg aacatataaa
     3121 caatacggaa cagagataga atcctgtaca tcataaatgt tactgtactg ttgagcatta
     3181 tgagcttgaa tataaaactc aaaatcagtc gttattaatc catcatcatg aatagtagta
     3241 ccacaacttt ttacaattaa tggaccaaaa atttgtgctt ttaacaactg caaatgttga
     3301 tgaaatctat taatttcctg atctacatct tctacttttg tatcatgtaa ctttttacag
     3361 ataactgact ttagtaccag ttttttatta tcttttacct ctaacttagc cataagtaac
     3421 ctcctctgta tctaacacag cctgtgactg aatttgttga ttcacttgaa cgctctgcaa
     3481 accaaccatt ctagcatact ttccattttt cgccattagt tcttcatgag tcccatattc
     3541 cacaatagtc ccattttcta aaaagcatat cttatcacat cgaagaattg tagacagcct
     3601 gtgggctact acaattgttg tcttatccat tattttatta aagattaaat cctgaataat
     3661 ctgttcacta aatgaatcta agttagaggt tgcctcatca aatatataca aatcagcttt
     3721 actcagtagt gctcttgcaa tagccaatcg ttgtttctct ccacccgaga aattttgacc
     3781 gccttcttct acaaaggagc cataacgatt ttgaaggcgt tgaatcgtat catgaatacc
     3841 aacaatacga caaactctca ccatatcctc atatgtaaca gaaggattac caatttttag
     3901 attatcaata attgtccctg taaagagttc tatggtctga ggaatgtagg aaattttctt
     3961 acgtagttta ccatagtcaa gatctgataa gtcattttct cctatacgaa ttttcccctc
     4021 actcggattt ataaatctta ataacaaacg aactagcgta ctttttcctg ctccgctttc
     4081 tccaacaaaa gctatttttt ctccttgttt aattcgcaaa ttaaagtcct tgataacagg
     4141 agggcgtgaa ccataggcaa atgttacatc tttaaattca atgtcatcac ataaggtgaa
     4201 gtctctaata ctataatcca aggcaatgtc ttcacgatct acttccatca attcttgaag
     4261 ccgactaacc gcaacctgta cctcttgaaa ggttaactgc aagccaacta aattctgaat
     4321 aggttctgta aaatattgac ttaatgtctg aaaaaccaag aggtccccaa tagtcatttt
     4381 tccatcaatg ataaataagg cgcccactcc cataaataat aacccaccca tggttgaggt
     4441 cattgaagat attgtagatt gaatattctg caaaacaccc tctttataac caatttctaa
     4501 agtatgaaca aatttttctt caattttgtt taaacgttgt tcctcatcat gctgagactt
     4561 aatggtatca atgttacgaa tagattcaat taactgtgaa ttaagaagtc catttgcttc
     4621 catttgttca tgattaattt ttttataagg ctttttaaaa cagtatataa gaatgatgtt
     4681 aacaataacc ataaaaacta atatcagaaa taaagattga ttaatagtcc aaaggacaac
     4741 cgcactaata actgacaagg tgatatccat gactaatgaa atagagactg acgtaaacac
     4801 attctttatc gtcatcgcat cttgaaatct tgttaaaaca tcaccaactc tacgacttcc
     4861 aaaaaaacta taaggaagat gaataatatg gtcataatat cccattaaaa ccggtatatc
     4921 aatttttcga gatagaaaca aaagaacgtg ctgacgaaat gcagatagaa gagtctgtaa
     4981 gaacgacact attccaaata ctatcaaaaa catatacaga ctatttttta aagcatatgg
     5041 aatcacctcg tccatgataa cttttgaaaa gagactcgat aaaataccaa tgatacttaa
     5101 aacaaaggaa gctaatatga ctgtactaat caatcctttt tgattaaaaa ttaaccttcc
     5161 aaataaatca agaagtcctt ttccctttag tttccctctt tcaaaatccg aatttggaac
     5221 cataaaaaga gtaatacctt gataaatttc tcccagttcg tcacttgaca tcttgcgtat
     5281 gccactagca gggtctgcta cgtagaactt actattcctt ttgatactat gtagtaccac
     5341 aaaatgattt tgacctaaat cattcttaac ttgaagaatc gcaggaaatg ttaattttgg
     5401 agtcaaatct tccagtgcta ctcgaacagc ttttactgta aaattcaact tattcagacc
     5461 tgaaacaata ccactgacag tcgttccata catgtctgta ccaataattt ccctaatctt
     5521 catgattgat agttcctttt tgtaagataa aagaactgtt gaaacaactg ccgcagcaca
     5581 atctgactgg tcatgttgca tcgtacaagg atattttttt aacatagaaa tactcaattc
     5641 tttagaatta atctaacttt tctttgatgt cacccaaacc tcaatcactg cccagtagtt
     5701 cttgaattaa tttattttca accgtatcat tctttgttct tgatatcttt ccaagcattg
     5761 tagtacagca gatttttgcc caaggactga gcctccttta acaactcaaa ctcccttaca
     5821 ttatatcggc cagccccata gaaagattat agccagacta atcaatgata taatacatac
     5881 tagaatacaa aatatttttt tattcatact ttttctccta tctttatttt ctacctacat
     5941 agtacctctt attaagctca ttttaaaatt acgttaactt ttttcacaaa tttatttcga
     6001 ctttcttttt tactttttac attgctatga tacaatattt ttaacaaaat tttattgttt
     6061 gttaactttt ttcacgaaaa ggagaaaatc atgcgttatg atttcggaaa ggtctataaa
     6121 gaaatacgtg agtcaaaggg gctgacccaa gaagaggtct gtgggggtgt tctctcaaga
     6181 accagcttat caaaaatcga aagtggcaag acaaccccaa aatatgaaaa tatggaattt
     6241 cttctccgtc aaatcaatat gagttttgaa gagtttgaat atatctgtca actttatcaa
     6301 ccaagtcaac gcacagagat tatgcaaacc tatctcaata tgcgttccat tatcgggacc
     6361 agcgatcttg tcaatttatt tcaaaaatgc caagactacc tcaagaccca ccacgatctc
     6421 cctatagaag aaatcagaga tatgcttgaa gttgttattt atctccgtca acacggggca
     6481 ggggaactat caaaacacgc agaacaggtt gtcaaaaaac tttggaaaaa aattgaaaaa
     6541 caagatacat ggtatgagag tgatctaaaa atcctcaata ccattctttt cagttttccc
     6601 attgaatacc tccatctcat cactggaaaa atattgcaac gcctagaagt ctataaaaac
     6661 tatcaacatt tatatgactt gcgaatgaca attctattaa acctttccac actctatcta
     6721 tacaatcaag ataaaaacat gtgtaagcaa atctgctata ctttactgga ggacgccaag
     6781 aataagaaaa gctacgatag gctggctatc tgctatgtcc gtattgggat ttgtagggat
     6841 gatgcgaaac ttatccaaaa agggttctcc cttctggagc taaccgagga aacttctata
     6901 ctgtctcatc tcaaaaaaga agtagagatc tattaccaag cgaaggaaag ataaaaaagc
     6961 cgagggattt cctcgactct ttacatatta tttgttcgtt agttcttaat accagccatt
     7021 gttaagccag aagtttttag cagcagtcca tgaaccgtaa cgtcctgcaa cgtaggcatc
     7081 tgctacacgt tcttggtttt cagctgagta gtcaccgttc aggtatgaat ctgttaattg
     7141 gtaacgtccg atataacgtc catttgtagc tgtatagcta ccacctgatt ctttttgagc
     7201 gatccattct ttggcttctg cttcagatcc gcttacagtt gaaacaactg tttcacttac
     7261 tactggagtt tctgctactg gagctgaaac agtttcatct tgagcggctg gtgccgcata
     7321 agtagctggc gctggtgttg caacaggcgc tacagggcca tcgataacca actcttgatc
     7381 aacataaatc aaatgaatgt tatcaatgtg gttgttttct gccaattttt caactgttgt
     7441 gttgtgagtt tcagcgattt ctgaaagtgt atcaccttct ttaacagtgt aagttgatga
     7501 ttcttgagca gatacaaatg atggagcaaa tactgcaaac aaggcagcta ctcctgcaag
     7561 agttgcttta atctttttag ttattgattt catattcgaa aattctcctt ctttctatag
     7621 ttctatcata ccctttaaat attaccgttt cttgacactt ttatgtagaa atattacaaa
     7681 attatttttt atttccctaa ataaggtgtt ttttgtcata aaagatacta tttttatgct
     7741 atttgaggta ttagaaaggt tttcatccac aattaaagcc aagcccctca ttctttgata
     7801 taatagagat aagaattttt ataaggggaa actgatgaaa tcacttcgtt ttcaatctgt
     7861 ctttgatatc atcggaccag ttatgattgg cccatctagt agccataccg ctggtgctgt
     7921 tcgtattggg aagattgtct cttccatttt tgatgatact ccgacagaag ttgaattcca
     7981 actttttaac tcatttgcca agacctatcg tggtcacgga acagacctag cccttgttgc
     8041 aggtatttta ggaatggata cagatgatcc tgaaattcca aatagtctgg aaattgccca
     8101 caagcgtggt atcaagattg tctggaccat tcagaaagac agcaatgccc ctcaccctaa
     8161 caccactaaa attactgtta aaaatgccca caagaccatc agcgtgactg gtatttctat
     8221 cggtggagga aatattcagg taaccgaact caatggtttt gccgtctctc tcaatatgaa
     8281 tacaccgact atcatcatcg ttcatcaaga tattccaggt atgattgccc ttgttacaga
     8341 ggcgctttcc cgctatggta tcaatatcgc ccagatgaat gtcactcgtg aaaaagctgg
     8401 tgaaaaagcc attatgatta tcgaagttga cagtcgcaac tgtgatgagg ctatcgaaga
     8461 aattcgaaaa atccctcatc tccacaatgt caatttcttt aaataggagg aagcatgttt
     8521 tattctatca aagaattggt cgagcaagca gatctggact ttcaaggaaa tgtcgcagaa
     8581 ctcatgatta caacagagtt tgaattgacc ggtcgcgaac gtgaagaagt cttccttctc
     8641 atggaacgca atctggaagt tatgaaagcc tctgtccaac ttggcctcaa tgaaaataaa
     8701 tctcgtagtg gcctgacagg tggagatgct gccaaattgg atcactacat cgaaaacgga
     8761 aaaactctgt cagattatac gattctctcg gctgcccgaa atgccatcgc agtcaatgaa
     8821 cacaatgcca aaatgggctt ggtctgtgcc actccaaccg ctggaagtgc tggctgtctg
     8881 ccatccgttc tcactgctgc tattgaaaaa ttagacctca gccacgagca acaattggat
     8941 ttcctctttg ctgctggtgc ctttggacta gtcatcgcaa acaatgcctc catctcaggt
     9001 gctgagggtg ggtgtcaagc tgaagttggt tcagcctctg ctatgagtgc tgccgccttg
     9061 actctggctg caggtggaac accttatcag gccagtcaag ctattgcctt tgtcattaaa
     9121 aatatgctag gcctcatctg tgaccctgtt gcaggtttgg tcgaagttcc ctgtgtcaaa
     9181 cgtaatgcca tgggagctag ctttgctttc atcgcagcag acatggcctt ggcaggtatc
     9241 gaatctaaaa tccctgtgga tgaagtgatc gatgccatgt accaagtagg agcaagcatg
     9301 ccaactgcct ttcgtgaaac agctgaaggt ggactcgcta ccacccctac tggtcgtcgc
     9361 ctccaaaaag aaattttcgg agaataagct tatcaaatag gagaaaccat gacctctatc
     9421 acagcgattt ttttcgattt ggatggaacc ctcgttgata gttctatcgg gattcacaat
     9481 gcctttacct atacctttaa agagctgggg gtgcctagcc ctgatgccaa aactattcgt
     9541 ggttttatgg gaccacctct cgaaagtagt tttgcgacct gcctgtccaa agaccaaatt
     9601 tctgaagcct tgcagatata tcgttcttac tataaggcaa aaggcatcta tgaagctcaa
     9661 ctctttcctc agattataga cttgcttgag gagttatcga gcagttatcc actctacatc
     9721 accacgacaa aggatacatc tactgctcaa gacatggcaa aaaacttgga aatccatcat
     9781 ttctttgatg gcatttatgg ttctagccct gaagcacccc ataaggcaga tgtcattcac
     9841 caagccttgc agacacatca actagcacca gaacaagcca tcatcatcgg agataccaag
     9901 tttgatatgc tgggagctcg agaaacaggt attcagaaat tggccatcac ttggggattt
     9961 ggagagcaag cagatctact aaactatcaa cctgattata tcgctcacaa acccttagaa
    10021 gttttggcgt attttcaata gcatagactg ggtaacaatt ccatttcaga agaaaatgaa
    10081 gtaatactca atgaaaatca aagagcaaac taggaaacta gctgcgggca gctcaaaaca
    10141 ctgttttaag gttgtggata gaactgacga agtcagctca aaacactgtt ttgaggttgt
    10201 ggatagaact gacgaagtca gtaaccatat acggcaaggc gacgttgacg tggtttgaag
    10261 agattttcga agagtataag tctctacata ataaaacgca tattaccaag gttgttaact
    10321 tgataatatg cgtttttctt ttttattcaa tgtgggttgt ttgattagca aaggcgataa
    10381 tagcttgctt caactcatct ccactgagag tgcggaactc tccaatcttt tgattgatgg
    10441 attctaaagg catgacatta accttaccaa cgaaaatctt atccataact tgattatcaa
    10501 cgagttcggt tgataccaag agttcttcgt agagtttttc acctgggcgg attccaactt
    10561 caacgattgg aatttcactt tcagtgtggc cacttagaag caccatcttc ttggccaagt
    10621 cataaatctt gactggtttg cccatatcaa ggataaagac ttccccatct ttggcataag
    10681 caccagcatg gataaccaga cggctagctt ctggaatggt cataaagtaa cgggtcatgc
    10741 ggaagtctgt caccgttaca ggcccacctt cagcaatctg acgttcaaag actggaatga
    10801 cactaccacg gctaccaaga acattcccaa aacgaactgc acagtaggtt gattggctac
    10861 gttggttaaa gccagtgaca atcaactccg ccacgcgctt ggttgctccc ataacatttg
    10921 gtggattgac tgccttatct gtcgaaatca taaccatctt agacacttta gcttcatcaa
    10981 cagccttagc aacattgtaa gttccacgga tattgttttt gaaggcttct tttggattgc
    11041 gctccatcat aggaacatgc ttgtgggctg ccgcatgata aacaatagca ggtttgtact
    11101 gctcaaagac ttgcaacaaa cgatcatagt cttgaatgtc cgcaatcaca ggtacataat
    11161 caatcccttg gaacttacga atcaattcat gataaacaag gtagattgag ttttccccat
    11221 gaccgagcaa gacaatgcgt tcaggattga agcgactaac ttgacgacag atttcagaac
    11281 cgattgaacc tccagctcct gtgactaaga tggtcttacc tgtcagttct gcacccagac
    11341 gcgattcgtc aagacggatt tcctgacgac ctaaaaggtc cgtaatatca attttttgga
    11401 agccagtacc tgcttggtga aggccctgaa caacagtttc aaccttaggc atcttgtaac
    11461 atttgacacc cagcttatta cacatctgca agatacgctc atattctgac ggatccaacg
    11521 acggaatcgc aacgatgaca cgctcgattt gatggcgttt ggctaattca ggcagattgt
    11581 cataagagcc caaaacagga ataccaccaa gtttttgacc ctttttctta gaatccttat
    11641 ccaaaatacc gaccagttct aattcactgg ttggatgttg gtaactatcc ataaagagag
    11701 ccccaccatc accggcacca atcaagaagg tccgacggtg ttctccatca ccactacctt
    11761 ttttgcgtct ggagtagatt aactgccaag taatccgtgg caataaaatc aagaaggtac
    11821 tcaacaagat aaagagaatg ataaaacgga tggagaagag tggcaagaag gcataacaga
    11881 tactatatga caagacactg ctagcagtca caccaaaaaa gattttcatg aaatccgtaa
    11941 tcttgctgta acgactaatg ctcgcgttca acccccaaaa accaatcatc aattgataga
    12001 acaggaaggc caaactcgta tagataatgt agtcaacagg tgctggatta atcagcccat
    12061 aaaataaaat ataagataca atgatggaaa ccaccatact gaaaatatca aatattcccc
    12121 agaaaacctg cttttgttgt ttatttaaaa tttccaccag atcaatcaca taatctgtta
    12181 gttttttatt catagaaatc tactcctcct taaaagagtt ttactatatt gttattatag
    12241 catattttta tttatttggc ttattttatc taaataaatt attgttctct tgtactcctt
    12301 cttccattta aatcctctaa ttaaacctac aatcgtccca aagccataag caaagtgaat
    12361 ggaaaataaa agaaagggca tcacaattag aaatccattt ttatgtttta ataaagtcag
    12421 caaagtgagt agtgacaaaa gtagaaaata ggcacctaat agtaaagtta tgaatacgaa
    12481 tgtgatcggt aacaatgcta gactaaacac aagactcaaa acaaataaac aaggaacata
    12541 gtgaaataat gataaacact taaactgaac atgacttgtc aagccaatcc acaaaccatt
    12601 taaatacttt tgatgcagca ttttcttgaa tgttggtcga atatactgat aagatagaat
    12661 acttgggcta tagcggattt tataaccatg ttctcgaatt ctataatgaa tatcattatc
    12721 ttcagttcgg ccaagttgct catttactaa accaactttc tggaaaacct ctcgtttata
    12781 catcccatga aaaatagaag aaacatatct atcctcggaa ctatttcgat aattggcaat
    12841 actactgcca aacatatttt cctcaacaag atgcaaggtc tctgcccatt ttccttttcc
    12901 ttcgacaatc gtcggtctag gccccccaca gacaaattca ccttgttgaa taatagccac
    12961 attgttcatt acaaaagtct cagtaacttt tgaatgagca tcaattttta aaataaggtc
    13021 ccctacagaa tgtttaactc ccaggttaaa accactagct tgatttttct taggattgtt
    13081 atacaatcta attgagttaa actctgtatc ttcctttata aattgctgaa tgatagctgt
    13141 ggtcccatct gtggatatag catttataaa tagaatttca atattctctt taggataagt
    13201 ttgatttttt aagtcttcaa ttagaccagg cagatatttt tcttcattgt atgcactgat
    13261 tacaatggat acgagaagac tttcaacatt ttgagtcact actactctcc tgaatttttc
    13321 cttccaccat tctatcataa ttttcaagac tttcccattt ttatcttgaa agccagaaac
    13381 cttacttgac attatagtga aaaagcctta aaataagctg ttattaaaat cagctagaag
    13441 aggtattata tgaaaaagca atcactcttt tttgttccag gtattatcct gattggtgtt
    13501 tccttgcgaa ctccttttac tgttttaccc attattttgg gaaatatttc gcaaggtctg
    13561 gaggtagaag ttagttcgct tggtgtcttg accagcctgc ctctccttat gtttaccctc
    13621 ttttcaccat tttctaccca actggctcag aaaatcggct tggagcatct cttcacctac
    13681 agcctcttct tcttgaccat cggctcactt attcgactaa tcaatctgcc cctgctctat
    13741 ctaggaacct tgatggttgg ggcaagtgtc gcagtcatca atgtcctgct tcctagtctt
    13801 atccaagcca atcaaccaaa gaaaattggt tttctgacca ccttatatgt aacgtctatg
    13861 gggattgcaa cggctctggc ttcctatcta gctgtgccca ttacacaagc cagttcttgg
    13921 aaaggactta tccttctcct cacgttactc tgtctagcaa cttttttggt ctggctccca
    13981 aatcaccgct ataatcatag actagctcca caaaccaaac aaaaaagtca aataaaggtc
    14041 atgcgtaata aacaggtttg ggcaattatt atcttttcag gttttcaatc cttgatcttt
    14101 tacaccgtca tgacctggtt acctaccatg tctatccatg caggtctatc cagtcacgaa
    14161 gctggcttgc tgacttctat cttatctctg attagcattc ctttttcaat gaccatccca
    14221 agcctgacaa ccagtttatc tactcgcaac cgtcagctca tgctcactct ggtttcacta
    14281 gctggtgtgg tcggcatttc catgctcttt ttcccaatca ataatttcat ttactggctt
    14341 gccatccatc tcctcatcgg aaccgcaacc agcgccctct tcccttatct catggtcaac
    14401 ttttcactca agacaagcgc ccctgaaaag acagcccaat tgtccggcct atctcaaaca
    14461 ggaggctata tcctagcagc ctttgggcca accctctttg gttacagttt tgacctgttc
    14521 cactcttggg taccagctgt agctgccctc ttgctcatcg atatcctgat gactgtggcc
    14581 ctctttacag tggacagagc ggataagatc ctttaaactt ctagttttag ctagaagttt
    14641 tttatatata aaaattttac acatttctct tgacagggct ttcttttaga tgtacaatgt
    14701 atgtgtagaa aaattatata taaaaatctt acacattaga aaaggaggtt tcccatgtac
    14761 tttccaacat cctctgcctt gattgaattt ctcatcttgg ccgtactgga gcagggtgat
    14821 tcttatggtt atgagattag ccaaaccatt aagctaatcg ctaatatcaa agaatccaca
    14881 ctctatccca ttctcaaaaa attggaaggc aatagctttc tgacaaccta ttctagagag
    14941 ttccaaggtc gcatgcgcaa atactactcc ttgacaaacg gtggtataga gcagctcttg
    15001 accctaaaag atgaatgggc actctataca gacaccatca atggcatcat agaagggagt
    15061 atccgccatg acaagaactg aatacctgac tcagctagaa ctctatctca agaaactacc
    15121 tgaagctgac cgtatcgaag ccatggacta tttcagagag ctctttgacg atgctggagt
    15181 cgaaggagaa gaagaactca tcgctagttt gggaactccc aaagaagcgg cccacgaagt
    15241 tctatccaat cttctcgata aaaaaatcaa tgaagcaccc gctcaaaaaa ataaccgaca
    15301 aattttacat atcgccttgt tagccctcct tgcagcacct atcggcattc ctctgggaat
    15361 cgccatcctc gtgaccctgt tcgcaatcct tgtagccgct ttgactgtca ttctggcttt
    15421 ctttgcagtt tccatactgg gtatcatcgg cggattccta tttttagttg aaagtttcac
    15481 tatcctcgcc caagccaaat cagcctttat cttgattttt ggttctggtt tactggctat
    15541 cggtgcttct tcgctagttt tacttggcat ttcctatgta gctcgcttct tcggtctact
    15601 cattgttcgt ctggtacaat ttgttcttaa aaaaggaaag agaggtaatc agcatgcgta
    15661 aatggacaaa aggatttctc atctttggtg tggtgactac cgttatcggc tttatcctgc
    15721 tttttgtagg tatccaatct gacgggatta agagcctact ttccatgtcc aaagaacctg
    15781 tctatgatag ccgtacggaa aagctaacct ttggcaagga agtcgaaaac ctagaaatta
    15841 ctctccacca acacacgctc accatcacag actctttcga tgatcaaatc cacatttctt
    15901 accatccatc tctttctgct caccatgatt ttatcaccaa tcagaacgat agaactctga
    15961 gtctcactga taagaaactg tctgaaactc cgtttctctc ttctggaatt ggtgggattc
    16021 ttcatatcgc aagtagctac tctagtcgtt ttgaagaagt tattctccga ctaccaaaag
    16081 ggagaactct aaaagggatc aacatctcag ccaatcgcgg acaaaccacc atcataaatg
    16141 ctagccttga aaatgcgacc ctcaatacaa acagctatat cctccgaatt gaaggaagtc
    16201 gtatcaaaaa cagtaaactc acaacgccca atatcgttaa tatctttgat acagttctta
    16261 cagatagtca gctagagtca acagataatc acttccacgc tgaaaatatc caagtccatg
    16321 gtaaggttga actgactgcc aaagattatc tcagaatcat cctagaccag aaagaaagcc
    16381 aacgaattaa ctgggacatc tcaagtaact acggttctat cttccaattc acaagagaaa
    16441 agcctgaatc aagaggtacg gaattaagca acccttacaa aactgaaaaa accgatgtca
    16501 aggatcaact cattgcgaga tctgatgata atattgatct aatatccaca ccaagcagac
    16561 gttgacaaaa acgcttacat ctgctactat ggaagcatat ttatctaacc aaaaggaggt
    16621 tctaccatga aacaagaatg gtttgaaagt aatgattttg taaaaacaac aagcaagaac
    16681 aagcctgaag agcaagctca agaggttgca gacaaggctg aagaaacgat agccgatttc
    16741 gatacaccaa ttggaaaaaa tactcaagta gaggaggaag tctctcaagc tgaagtcgaa
    16801 ctggaaagcc agcaagaaga gaaaattgaa actcctgaag tcggtgaagc gagaacagaa
    16861 atagaagaaa agaaggcatc taattctact gaagaagagt cagacctttc taaagaaaca
    16921 gaaaaagtca ctatagctga agagagccaa gaagctcttc ctcagcaaaa agcaaccacg
    16981 aaagagccac ttcttatcag taaatcttta gaaagtcctt atatccccga ccaagctcca
    17041 aaatctaggg ataaatggaa agagcaagtg cttgattttt ggtcttggct agtggaagcg
    17101 atcaaatctc ctacaagtaa gtttgaaaca agtatcacac acagttacac agcctttctc
    17161 ttgctcattc tgttttctgc atcttccttt ttctttagta tctatcacat caaacatgct
    17221 tactatggac atatagcaag cattaacagt cgcttccctg agcagctagc tcctttaact
    17281 cttttttcta tcatctctat cctagtagcg acaacactct tcttcttttc attcctcttg
    17341 ggtagtttcg ttgtgagacg atttatccac caggaaaagg actggacgct agacaaggtt
    17401 ctccaacaat atagtcaact cttggcaatt ccaatcttcc tcactgctat tgctagtttc
    17461 tttgctttct ttgatagcct acgatttaca gctctcttgt gtgtgattag cattggaatc
    17521 attctgcttg ccagtctcca tatcattaca agaccaagtc aagcaagtga aaccgactcc
    17581 ttctatcaat tattcttgtc tgtccttgtg aacggagtta ttatcctcct cttctttgta
    17641 gctgaagtgg cactgattgg agattatctt cgtatcttgg cctttcttta aaattcaatc
    17701 ctgtcatcct tggcaggatt ttttctatgt caaaaaagca agtcgattga cctgcttctg
    17761 ctttactttt cttgtgctaa tgttttaaaa tcttgtccta ggatgggttt tattcctaga
    17821 gttcaaagta tgatagcgtt gctataaagt tcgttattcc aaatattatg caaactagtt
    17881 atatgtaaaa ttaagattag aaaccaccaa tctccattta ttaactttta atgaaattcg
    17941 tccatattaa taactttact tgctctagca ataacatcct tgtcatgagt cacgacaata
    18001 acaatctttt cctcgttcac taatttctca acctcgttta gaaataattc agttgagttt
    18061 ctgtccaaat ttcctgtagg ctcatcgaat gaatagatat ccttttcttg cgataaactc
    18121 ctcatgaata gaattttttg tttctgacct tacgaaatat tggtggcttt cccatcaatc
    18181 tgatgactca gagctatatt gagattcaaa ctatcaagat tatttgattc atagttttcc
    18241 ttatcaaata gggtgaaatt aatatttttt gtcatgcttc atcacctcca gatatagtat
    18301 taaaatttta gatcagttga ctatccgtgt cgaatctttc atagaaactc ttgttattat
    18361 agaaataaat aacaaattat tagtacatga ataataaatc tgatacaatg gtgactataa
    18421 ttgattttat ttccactaat ctttctatcg tagagcaagc tcactgaaag
//
LOCUS       DAVLUM010000042        17698 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLUM010000042 DAVLUM010000000
VERSION     DAVLUM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.042"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(63..1004)
                     /locus_tag="VYN42_001329"
     CDS             complement(63..1004)
                     /locus_tag="VYN42_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1462396.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(982..2745)
                     /gene="aspS"
                     /locus_tag="VYN42_001330"
     CDS             complement(982..2745)
                     /gene="aspS"
                     /locus_tag="VYN42_001330"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1462397.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(2981..3061)
                     /locus_tag="VYN42_001331"
                     /pseudo
     CDS             complement(2981..3061)
                     /locus_tag="VYN42_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3097..3327)
                     /locus_tag="VYN42_001332"
     CDS             complement(3097..3327)
                     /locus_tag="VYN42_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462398.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(3345..3986)
                     /locus_tag="VYN42_001333"
     CDS             complement(3345..3986)
                     /locus_tag="VYN42_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462399.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(3998..4732)
                     /locus_tag="VYN42_001334"
     CDS             complement(3998..4732)
                     /locus_tag="VYN42_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1462400.1"
                     /translation="MKKKRRLLFLMSIVFWGVLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(4735..4932)
                     /locus_tag="VYN42_001335"
     CDS             complement(4735..4932)
                     /locus_tag="VYN42_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462401.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(4932..5138)
                     /locus_tag="VYN42_001336"
     CDS             complement(4932..5138)
                     /locus_tag="VYN42_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462402.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(5148..5462)
                     /locus_tag="VYN42_001337"
     CDS             complement(5148..5462)
                     /locus_tag="VYN42_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462403.1"
                     /translation="MWVLVFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKKPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(5729..5809)
                     /locus_tag="VYN42_001338"
                     /pseudo
     CDS             complement(5729..5809)
                     /locus_tag="VYN42_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(5800..7089)
                     /locus_tag="VYN42_001339"
     CDS             complement(5800..7089)
                     /locus_tag="VYN42_001339"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1462404.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(7167..8414)
                     /locus_tag="VYN42_001340"
     CDS             complement(7167..8414)
                     /locus_tag="VYN42_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1462405.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLPQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDRFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            complement(8604..9455)
                     /gene="rgg"
                     /locus_tag="VYN42_001341"
     CDS             complement(8604..9455)
                     /gene="rgg"
                     /locus_tag="VYN42_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1462406.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYKLNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            9579..9920
                     /locus_tag="VYN42_001342"
     CDS             9579..9920
                     /locus_tag="VYN42_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1462407.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            9978..10058
                     /locus_tag="VYN42_001343"
                     /pseudo
     CDS             9978..10058
                     /locus_tag="VYN42_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10264..11967)
                     /gene="ilvD"
                     /locus_tag="VYN42_001344"
     CDS             complement(10264..11967)
                     /gene="ilvD"
                     /locus_tag="VYN42_001344"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1462408.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(12200..13132)
                     /locus_tag="VYN42_001345"
     CDS             complement(12200..13132)
                     /locus_tag="VYN42_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1462409.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(13129..13986)
                     /locus_tag="VYN42_001346"
     CDS             complement(13129..13986)
                     /locus_tag="VYN42_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1462410.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(13990..15336)
                     /locus_tag="VYN42_001347"
     CDS             complement(13990..15336)
                     /locus_tag="VYN42_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1462411.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(15349..15633)
                     /locus_tag="VYN42_001348"
     CDS             complement(15349..15633)
                     /locus_tag="VYN42_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1462412.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(15637..17667)
                     /locus_tag="VYN42_001349"
     CDS             complement(15637..17667)
                     /locus_tag="VYN42_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1462413.1"
                     /translation="MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
BASE COUNT         5598 a         3864 c         3092 g         5144 t
ORIGIN      
        1 aacatatata cggcaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtattaat
       61 cactaattat ctatctcaac aaatcttcct agaatatgaa cattttccga gacagagaca
      121 aaggagcttg gatccacttg tgtcataatc tgtttaaatt cattaaactc tgcacgtgta
      181 atgacagtga ttaaaactgc ctttctctcg tgattatagg ttccttctgc atcgtggatc
      241 atggttgctc cgcggtgcaa ttttttatgg attttttcaa ttaccttctc tggatgattt
      301 gtcacaatca tggcctgcat acgcttttgc ttagtaaaga ctgcgtctgt cacacggcta
      361 gagacaaaga tggtaatcat agaataaaga gcgtatttcc aaccaaaggt caaacctgct
      421 atcagcatga tagttccatt taccaagaaa gaaatactac cgacattctt acccgttttc
      481 ttgcgaatag tcaggctgac gatatccgtc ccaccactgg agatattgtt tcgaagagca
      541 aaaccaatcc ccaaacccat aacaacaccc ccaaaaaggg aattgataat gggatcctcc
      601 gtcaaggttg ccacagggac aaactggata aagaaggaac tcatagatac cgtgataaag
      661 gtaaagacgg tgaacttatg gccaatctga taccaagcta agaccatcaa agggaagtta
      721 atggcgtaga agcttagcga aatcggaata tgaaaaccaa accagtgatt actcaaggca
      781 gagataatct gtgccagacc tgttgcacca ctcgaataca catgccctgg ttggaaaaag
      841 aaattaactg ctactgctga taaaaaacca tagaccagag aggccgaaat cttctcatca
      901 tacttttctc gagagatact ttgtaagaca cgtaaaattt ttatctgata agcaaagcgg
      961 cgcagataat agcgccaccg cttaattcgt tttgtttgtt tcatcttctt ctacttgtaa
     1021 gctgagttcc tctagttgtt tgagagcgac tgttgatgga gcttgtgtca ttgggtcagt
     1081 tgccttgttg ttcttaggaa aggcaatgac ttcacggata ttttcttctc cagcaagcaa
     1141 catgacaaaa cggtcaagcc cgatagccaa accaccgtgt ggtgggaaac catagtccat
     1201 ggcttcaaga aggaaaccaa actggtcatt ggcttcttca gttgagaaac caagagcctt
     1261 gaacatgcgt tcttgaaggt ctttttggtt gatacgaagg ctaccaccac caagctcata
     1321 accgttcaag acgatatcgt aagcaatggc acgaacctta gccaaatcac cttctaattc
     1381 gtgagcagtc tcttcctgtg gaagtgtgaa aggatggtgg gcgctcatgt agcggccttc
     1441 ttcttcagac cattcaaaca tcggccagtc aaccacccaa aggaagttga acttatcatt
     1501 atcaatcaag ccaagctctt tagcaatacg tccacgaagg gcacccagtg ttgcattagc
     1561 cacttcaagc gtatccgcca caaagagaac caagtcctta tcttcaagaa caagcgctgt
     1621 tgtcaattct tcttggatac cagtcaagaa cttggcaact ggtccgttta attctccatc
     1681 aaccaccttg acccaagcaa gacctttggc accatactgt ttggctactt ccgtcatctt
     1741 gtcgatgtct ttacgtgaat agttgtccgc agctcctttg accacaatcg cttttacagc
     1801 aggtgcttct gaaaagactt taaagtctac acctttgacc acttctgtca agtcctgaag
     1861 caacatgtca aaacgagtat ctggcttgtc agaaccgtaa agagccatag catcatcgta
     1921 tttcatacga gggaatggta gcgttacttc gatgcctttt gtttccttca tcacgcgcgc
     1981 gatcaagcct tctgtaatat cttggatttc ttgctcagta aggaaggacg tttccaagtc
     2041 gacctgagta aattcaggct ggcggtctcc acgcaagtcc tcgtcacgga aacatttaac
     2101 gatttggtag taacggtcaa aaccagcatt catcaaaagc tgtttcgtga tttgtggact
     2161 ttgaggaaga gcgtaaaaat gccccttatt aacacgagac ggcactaaat aatcacgcgc
     2221 cccttcaggc gttgacttag aaaggaatgg tgtctccacg tcgataaact ccaactcatc
     2281 caaatagttg cggatagagt gggtcacctt ggcacgaagt ttaagatttt ccaacatttc
     2341 tggacgacga aggtcaaggt aacggtaacg caaacgtgta tcgtcatttg cctcaatgcc
     2401 atccttaatc tcaaatggtg ttgtcttagc tgtgttaagc acaataagag ctgtcacgtt
     2461 taactcaacc gcaccagttg gcaacttatc attggcttgc tcacgcgcag cgacctgacc
     2521 agtcacctca ataacaaatt cgctacgaag gctttcagct gttgccataa cctctgcaga
     2581 tactttttca gggttgataa ccaactgcat gattccttca cggtcacgaa gatcgataaa
     2641 gatcaaacca ccaaggtcac gacgacggcc aacccatcct ttcaaggtta tttcttgtcc
     2701 gatgtgttcc tcacgaacac gaccagcata catactacgt ttcattattt ctctcctctt
     2761 ttattctgtt actattttac cataaaagcg caggctcttc atgaaaatca tcagaaaagt
     2821 ttgccagtct ttaaaagtca ggtgaaagcc ctaaaaatta gcgctaatac tcttcgaaaa
     2881 tctcttcaaa ccacgtcagc gtcgccttac cgtaggtatt gttactgact tcgtcagttt
     2941 catctacaac ctcaaaacca tgttttgagc tgacttcgtc agttctatcc acaacctcaa
     3001 aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt
     3061 ataatacaaa aatccgatga acttcaccgg actcttttat tttgaatttt tgcctgcttt
     3121 acgcttttca gcgatttcgg ctgcctttcg aggcaagaca atttccgtta tgtaagccgt
     3181 cccaaaacgc agtacacctg caataggagc aaagacaact gctagatagt tatagaagaa
     3241 atcgcctttg aaggcataag ctagcgctcc aatgatgaaa aatagaacga ctgcctgaat
     3301 cactgctaat aaaattactc gtttcatgtg acctcctgac tctattatag catgagaatc
     3361 atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa tactgtagac cagacctttt
     3421 ctgctaacgt aagccaaacc caaactaaaa ccaaggctaa aatagacaaa aaattgttgc
     3481 acatcacctg gaaaatgaat caaggcaaat agaagactag ataccagaag aaaaatcagg
     3541 gttcgtttac tattgtcctg cttaggaaag agatagcgtg ctaacatccc tctaaaaaca
     3601 atctcttccg tcaaaggagc aaaaataacc acagcaaaga atgagaaaag tggttgagac
     3661 aaggtcaagt ctgtcgctat ttgctgattt actgaaggat catctggcaa gaagaattga
     3721 acgaccagag ataagaacca aaccaaggca ggaagccaaa taaatcggtt aaagccgctc
     3781 ttctcaatat aaacaggagc tttctgatac catttgtaaa tgccgtacac atatactcca
     3841 gccaagacca catagagtag agtaacagca tagggtgaag cgcctaaagc aagcgacgca
     3901 gtcgcgagcc cctgaataaa gccatagata aagaaaaagg atagaagggc tagaagaatc
     3961 cagccaaggt ttttaagtaa tttcatagat aactccttta tttgaaataa cgttttacca
     4021 taggtaactg catcacattg atataaacat ggatggctcc tacaagcaag aaagctagta
     4081 actgaatctc tcctgtcaag aaagaaatga taataagaaa aatatataag gctggtaaga
     4141 catattggtg taattggaat aaaattcgaa aactctgttc caaattagcc tgacgctccc
     4201 cttcatcata agaatttata tagttcaaga catcctttgg tgtagcgaaa aattccaaat
     4261 caaactgacg aacaatcgca atggttttaa aaagagattt ttgagcgact aagaatacca
     4321 caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt atgcaatata atcacctcac
     4381 ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt aatattaaaa gcaatggttc
     4441 caaactcaag attccgatac atttgcacat aataggtttc attcagatcg tcatccattt
     4501 cctcttgata caaggaatga aattttctgc ttttctttaa gaaattgaaa gtcaaaaaca
     4561 tactaatgaa acctatcagt aaacaaatag ctgatatcca tggcatcaag gcttttacat
     4621 ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat ccctacaaac atgcccaaga
     4681 ccccccaaaa gacaatagac atcaaaaata acaatctacg tttctttttc atattcattc
     4741 tcctttttca cttgctagat ttttggattt cttttcaatc cattcaatta ctgggatgag
     4801 agcaaagtag acccaaacaa attggtcgct ttgataggga ttaaaccagc ttaggtccat
     4861 cccaatcagt agaaatacgc tgactaataa agctatgacc actacataat aaatcacttt
     4921 atacttgttc atcactcgtc ctcctccaaa cgaaataccg attcgactgt ttcgttgaaa
     4981 atttgagata ttttcagggc aatgataatg gatggggtgt actcatcccg ttctagtagg
     5041 ctaatggtct gtctggaaac ccctgccagt ttggctaggt cggtttgatt gagaccatcg
     5101 cgagctcgaa gctcttttag acgatttttt agttgcacgt tacacaccta ctctccgtca
     5161 aattcaacgg tttggatatc ttcaatacgt tgcaacttga atttttcttt tcccgtatta
     5221 tctacacgtc gtagctttac ccattcctca tcaacatcca caacttccca gttatctggc
     5281 ccaatataca ctcccgttat aattggtttc tttccaatca tttcttgcaa taatctcgac
     5341 atttctgcgt ttcctttctc ttttcgctca agttttttga ttttattctc tagtttcttg
     5401 atttttttag aattattaga ataaaagaaa ataataaata gtataaatac tagtacccac
     5461 atcatagctc ctttcttctt ttctcttaac ttgcttacat tgtaacacat ctttttcttt
     5521 ttgacaagta tagctgtcaa aaagtttatg atttttgtca ttttgcaaaa gaaaaaggtc
     5581 aggagtaagt tcctgaccac tttatctatc attaatactc ttcgaaaatc tcttcaaacc
     5641 acgtcagctt cacctcgccg taggtatggt tactgacttc gtcagtttca tctacaacct
     5701 caaaaccatg ttttgagctg acttcgtcag ttctatccat aacttcaaaa cagtgttttg
     5761 agcaacctgc ggctagcttc ctagtttgct ctttgacttt cattgagtat aaaatcctag
     5821 tttttcaaag atttctgaga agttttggct gattgtctca agtgacactt gcacttcttc
     5881 tcgggtttgg ttgttcttga ccgtcacttg tccgctttcg acttcgctct ctcctagggt
     5941 gatgagggtc ttagccgcaa agacatcggc tgacttgaac tgagctttga gcttacggtt
     6001 gaggtaatca cgctctgctt tgaaaccttg ttggcgaaga gcttggacta gttctagggc
     6061 tttgacattt gctccatcac ccaagactgc gatatagaca tctagggcgt tttcgatagg
     6121 gagggccacg ccttgttttt caaggatgag aagcaggcgc tctacaccaa gcccaaaacc
     6181 aaatccagca gtttcagggc ctccaaagta agcaaccaaa ccatcgtagc gaccacccgc
     6241 acagactgtc aagtcattgc cctcaatctc tgtgataaac tcgaaaatgg tgtggttgta
     6301 gtagtccaga ccacgcacca tattggtatc gatgatgtaa tctactccaa gattttccaa
     6361 catctgacgc acagcatcaa aatgagtttg gctttcttca tcaagaaagt ccaagataga
     6421 cggcgcattc tctactgcca ccttgtcttc tttttcctta gagtccaaga cacgaagagg
     6481 attttcctcc aagcgacgtt ggctatcctt agacaaggtc tccttgagcg gtgtcaaata
     6541 gtcaatcaag gcttggcggt aggctgcacg gctctcagga tttccaagag tgttgaggtg
     6601 caatttgaca ccttgaatac cgatttcctt caaaaaatgg gctgccataa cgattgtttc
     6661 cacatcggta gctggattgc tagagccaaa acactcaaca ccaatctggt ggaattggcg
     6721 caagcgccct gcctgtggac gctcataacg gaacataggt cccatgtagt agaacttgct
     6781 tggcttttgc acttctgggg cgaagagttt attttccaca taggaacgga caacgggcgc
     6841 agttccttct ggacggaggg taatatggcg gtcacccttg tcatagaaat cgtacatttc
     6901 cttggttacg atatccgttg tatctccgac agagcggctg ataacctcgt aatgctcgaa
     6961 aataggcgta cgcacttctg cgtagttgta gcgcttgaaa atttcacggg caaagccctc
     7021 aacgtactgc cacttagcag actcagcagg taaaatatcc tgcgttcctt ttggtttttg
     7081 taatttcata gggaatcctc tttaaactta atagtcttat tttaccataa atagagggat
     7141 taaaacagta agaaaaaaat taggatttag atatcatttt tgagattaag aattgttaaa
     7201 aaaatagcta gcaaggaaaa accaacaaat agcatccaag tcaactgcat gttccatacg
     7261 gctactagtg aaaaacaagc tgttcccaca ggtatggata aggtaaacaa tagaccgaaa
     7321 aaattactag tacgagctag aacctctgga gctagatttt tcatgagcat ggcactaatc
     7381 tttggttgaa ctttaccaga cacatacaga gtaaagaaga gaaatagcaa accaagcacg
     7441 acttgattga ataaattagc caaaccaact agactaagtc ctacggtctc ccacatcatc
     7501 aatctaggca aggactgctt cccaaaataa tcattgcccg taaggctact gatgatgatt
     7561 gctactaaaa cacagaattg attgataaat agtgcctctg tataagaaaa attcaagaga
     7621 gaatggctca aaaagaagat attataaatt ccacccaaag cgccacccaa ggaattaata
     7681 agcaagacag caaagagcat aaaaccaaag tttttctgtc cacttttaag aaaaacgaga
     7741 cgtaaatttc ggtaaattgt taggaaccgg tctttgatag aaagcttctc attttttaag
     7801 ttttcaccat cagcagatga cattgacagg ctcaatttgc tttttcctaa aaagaggata
     7861 gtggctgata ctaggaaaaa gcaggcattg attcccgcaa cgagagaaaa attattgacc
     7921 gatagagcta agagccagac tccgaaagct tgaccaccaa tagctgaaat ataggtgatg
     7981 aactgtgaaa aagaataagc ctccatcaaa tcatcttcag ctactttttc cttaataaga
     8041 ggcatacgca ggccacctgc aaaatcactg atgacatcac taatgacatt gatcaaacac
     8101 aggctagaaa aggcaaagag actagcttgc tgaacaacta gggctgctag aaaaaataga
     8161 accgcctgaa acaaaccgct atagaccatc catttgacct tgtccctcgt gtaatctgcc
     8221 cgaatccctg caaaaactgt aaagagggtc ggaagaatca tgacaatatt cgccatagca
     8281 acagcaaaag atgcttgtgg caaggtcgat gcatagacga taaagaccag gttgaaaatc
     8341 gaagcaccaa aagcattgaa gaagcgtgac aaagtcaata ggcgataagc ttgatttcta
     8401 aacaatagtt tcatagataa tctccctcct tgttctaagt tctacatcaa gaatagcttt
     8461 agtatagcac ttatgaattt gcgaaacaat tcttttgaat atatgcaaca aataaaatga
     8521 gcaaaaaacg atagaacttt tgtaatgacc tgagaaaggg caacagttct atcgcttcaa
     8581 attttttctt agtttgcaga tattcaacat tcggtcgtat ttctatagta ttcggcagat
     8641 ttattacagc caagcatctc aaaaatacgg acagcatcct ccatcttttt ctggccttcc
     8701 ttgactctac cttgcttgct atcaaggaga ccttctgccc acagataaac aattcggaaa
     8761 taggtctcat tttccttgta gaaatgctct tcgataacac gtttaaaata ataggcattg
     8821 gtaaattctt cacactcaat actagctaaa aagccattca atagtatagt atgaaaaagg
     8881 tttcgattgc cagacatttc cattagaaaa tcagatttac gtaccatttc tcgtacatat
     8941 ctagtaaaaa gagaaacaga taaaaatgga gaactgactg aaaataaatt gagtttatag
     9001 attccccaga tctcggtaga aaacaaataa tcatgaagga cttttccttc ctctgctgtt
     9061 aactctaccc tttcatccat gctcttcata taagacttga tcataatggc atttagaata
     9121 tgtttctgtt tgttgtgaga atgggcatgc ttttgatact ccctgcgata taagtcctca
     9181 agaggtgcta tattctttgg ttccaagaca tctgtaattt cttttctcaa ctcagaatct
     9241 gtatcatact ggaaacctct cgccagaaag aggatctcct ccacactggc agatatattt
     9301 tccagagcaa atagaaactt ttccaccgaa agctcactct gacctgtttc aaaacgggac
     9361 aacatagacg gcgaaaattg tcctccggtt gcttgtctca gtgagatatt tcttgattct
     9421 cgtaattgtc taaagacttt tccaatctgc tccatagact tccccttgat cccgtatttt
     9481 cttcatttta tcatattttt cagaaaattc atcaaaaact tgccaaattg tcagaatcat
     9541 gagaaaatag aggatattta tcacgtggag ggactgctat gagagacgat atcaaaatca
     9601 atgaccgtgc tttggccttg caagaccaaa ttatcgaaaa actagagaaa gtttttgata
     9661 cagatgtgga attggatgtt tacaatctag gtctgattta tgaaatcaat ctggatgaaa
     9721 cggggctctg caagattgtc atgaccttca ccgatactgc ctgtgattgc gccgaaagcc
     9781 tgcctattga aatcgtggca ggtctgaaac aaatcgaggg tatcaaagat atcaaggttg
     9841 aagttacctg gtcgcctgct tggaaaatca cacgaatcag tcgctatggc cgtattgccc
     9901 ttggactacc acctcgttaa gcaggccaat cacttttaaa gatgaaaaaa gcaagccgaa
     9961 aatggcttgc tttttgatac tcaatgaaaa tcaaagggca aactagaaaa ctagccgcag
    10021 gttgctcaaa acactgtttt gaagttatgg atagaactga cgaagtcagc tcaaaacact
    10081 gttttgaggt tgtggataga actgacgaag tcagcccaaa acactgtttt gaggttgtgg
    10141 atagaactga cgaagtcagc ccaaaacact gttttgaggt tgtggataga actgacgaag
    10201 tcagtaacca tacctacggc aaggcgacgt tgacgtgatt tgaagagatt ttcgagtatg
    10261 agtttatttt ttacctgact tgtccatatt ccagaagtct gtcacggctc cgcgtgaagc
    10321 agatgatacg atgtgggcat atttaccgag gacaccacgg ctgtaaagtg gtggcaaggt
    10381 tgtttctgcc ttgcgttttt caagttcttc ttcggatacg gccatggaaa tttctttggt
    10441 atcttggtca accgtaacga tatcgccggt acggagatag gcaattggtc caccatcctg
    10501 agcttcagga gcgatatgtc caacaaccag accataagta ccaccagaga aacgtccgtc
    10561 cgtcaagagg gccaccttat ctccctgacc tttaccaaca atcattgaag aaagtgacag
    10621 catctcaggc ataccaggac cacctttagg tccaacaaaa cgaacaacga ctacatcgcc
    10681 atcaacgatt tcatctgtca gaacggcctg aatcgcatct tcttctgagt caaagacctt
    10741 agctggccca acgtgacgac gcactttaac acctgatacc ttggcaactg caccgtcagg
    10801 agcaaggttc ccgttcaaga tgataagcgg accatccgca cgttttggat tttcaagtgg
    10861 catgataact ttttggcctg gagtcaagtc tgcaaagtca gccaagtttt cagctacagt
    10921 cttaccagta catgtgatgc gatctccgtg aaggaaacca tttgccaaca agtacttcat
    10981 aaccgcaggg acaccaccga cttcgtagag gtcttggaag acatactgac cagatggttt
    11041 caagtcggcc aagtgaggca cacgttcttg aatcgtattg aagtcctcaa gtgacaagtc
    11101 aacatttgcg gcatgggcaa tggcgagcaa gtgaagagtg gcgtttgtag aaccaccgag
    11161 agccatcgtt acagtaatag catcttcaaa ggcttcacga gtcaagatat ctgatggttt
    11221 gagaccaagt tccaacatct taacaacagc acgtcctgct gcttcgatat cttctttctt
    11281 atcagctgat tcagctgggt gagaggatga ccctggcaaa ctcatcccta gaacttcgat
    11341 agcagttgcc atggtattag cagtatacat accaccacaa ccaccagggc cagggcaggc
    11401 attacattca agacgtttca cgtcctcagc tgtcatgtca ccgtggttcc attttccgat
    11461 accttcaaag acagaaacca agtcgatatc tttaccatca agatttcccg gtgcaatagt
    11521 tccaccatag gcgaaaatag ctgggatatc catattagca atagcaatca tagatccagg
    11581 catgttcttg tcacagccac cgatagcgac gaaggcatcc acgttgtgac cactcatagc
    11641 cgcctcgatg gagtccgcga tgatgtcacg agatgttaga gagaaacgca taccaggcgt
    11701 tcccatagcg atcccgtccg ctacggtaat ggttccaaac tgtacaggcc aagcgcctgc
    11761 agatttgaca ccttctttag ccagtttccc gaaatcatgc aagtgaatgt tacatggtgt
    11821 attttccgcc caagtcgaaa tcactcccac aatcgatgtt tcaaagtcct tatctgtcat
    11881 accagtcgca cgaagcatag cacggttagg tgatttaacc atgctgtcat agatgctact
    11941 gcggtgacgt ttatctaatt cagtcatctt atccctccca tttcagtttt tactattata
    12001 gcacaattta aaggcaatga acagaataaa attcttgaat tttcagaaaa ttctatacac
    12061 atgtgaaata tttaaaatta aaaacaacaa agcggattag tgcactttct gatgaccaga
    12121 atatgctttt taatccgctt tctttaaata acgtactgta atttttacag aaattctttc
    12181 agataagtgt atttaacatc tatcttgcat tataaatttc tagaaccttc tcttttatat
    12241 tcgattcact caaaccatac tcattaagaa gataatccat tttccctact tgaccgaatc
    12301 tttcttgaac acccatccga tgaatttttg ttattccatc atcagagaat aattcacata
    12361 aagcactgcc aattccacct atctgattgt gattttctac agtaaatata gtttttccac
    12421 ttaacattgt ttttatctgt tctggtatcg gtttgattct aaataaatct atcacaccta
    12481 ctgaataacc taatttagac agttcatctg caactcgaat acttggagca accattatgc
    12541 cagaagcaac gattacaaga tcttcaccat gccttaactc aatgtagcct ttagaaaaat
    12601 cttctccacc ttgatacaca ggaactggag cttttctaat tgttcgaata tattttagtc
    12661 cttttaagtc taatgtctgg ttcaatattt cacgaaattg gatatcatca gttgcttcga
    12721 aaatgattga tttaggaatt aaacgtaaca atccaatttc ttcaaatggc atatgtgttc
    12781 caccattcat ctctgccgtt actcctgcat ctgatccaat cacagtggca tccaattgtg
    12841 cgtatccaag agaaataaat aattgatcaa atactcttcg tgaagcaaaa ggaccaaatg
    12901 tatgaagata aggtctaaac ccctgaatag acaagcctgc tgcaaggccg accatttctg
    12961 cttccataat cccaacattc acataacggt ctccgaagtc cttttcaaga ttatgagtag
    13021 ccatcgaact tgacaaatcg gcttctaaga ctactatatc agaataactt tgattagcct
    13081 ctaaaaggaa gtctctatat acatgccgta attctttcgt acttctcatc attctgtttc
    13141 ctccaattcc tgacttaatc tttctacaac tgaagttaac atttgtttct cctctacagt
    13201 agggcgaaga tgatgattgg atttcatttc ttccagctct tgaacccctt gacctttaat
    13261 agtatctaat acaatgcact taggtgatga attatttgac tgttttaatt ggacaatccc
    13321 ttcataaatt tctctaatat ctgaaccctt gaccctaatg gattcaaatc caaatgctga
    13381 aaatttttct acgaaatcac ctggattaca aatatccttt gtaaaaccat ctaattgttt
    13441 tttgttctca tcaacaaata caattaagtt ggataactgt tgatgagaag caaactgtat
    13501 agcctcccaa cattgtcctt catttaactc accatctcca acaatagcat aagtataaaa
    13561 gggactcttt cttattctct gaccatatgc aagtccagtt gcaacactaa ttccttgtcc
    13621 taaagagccc gttgtcatat ctatgcctgg cgttagattt ctatcaggat gagacggtaa
    13681 tttggttcca tttgtattta aagaatataa gaattctttg tcaaagaaac cattcaaata
    13741 gagtgtactg tatagagctg gtcctccatg accttttgat aatatgaaat aatctctatc
    13801 tcgtgctgca aatatttctg gagtcattgg cattatttca ccataaagca ctgctaaaac
    13861 ttctacgata gacagacttc ctccgtaatg tccgaatcca agatgattca atgttctaag
    13921 agtatttaat cggatgttag tcgcaaattt tcttaactca tcttctctat ttttacttaa
    13981 aatcatccct tattcctcct ttgcagatgg ctttttaata aaggatactc caaacataac
    14041 tgctaaaata agaacaagac caatcacaat gcctgcttgt gagccaaatt gatttaacat
    14101 tcctaaaata attcctgata gaccaaaatc tgcatctgag aaagttgatc cttggaaacc
    14161 gagtcctccc aaaactggca ttaaaaagac tgggagaaaa ctgattaaaa taccttgtaa
    14221 aaatgctcca atagtggctc cacgaacacc accagatgca ttcccaataa cacctgcagt
    14281 cgctccacag aagaaatgag gcacaacgcc tggtaagata acaaccgttc ctgaagcaat
    14341 cataattgcc atacttacta aaccaccaat aaaactagag ataaatccaa ttagaactgc
    14401 attaggtgca taagtataaa caatcggaca atccaaagca ggttttgaat taggtacaag
    14461 acgctctgaa atacctttaa aggctggaac aatttcgccc aaaataaggc gaacacctgc
    14521 taaaataaca aatacccctg ctgcaaattg acctgctaat tgtaaagcat aaactagacc
    14581 acttgtacca ctactgattt ctttttctat atattctgac cctgcaaaga tagctacaat
    14641 aatgtaaata actgccatag ataaagtgat actaacagta ctatcacgta aaaaagctaa
    14701 actctttgga aatttaatgt cctctgttga ttttgatttg tcaccgataa ggctaccagt
    14761 aaaaccactc aaccaatatc ccaaagaact gaaatgacct aaagccacct tgtcatttcc
    14821 agttaattga accatatatt tttgcacaaa tgctggggaa atactcataa taataccgag
    14881 tgctaatcct cctagtaaga tgagaggcaa gctagtaaag ccagcaactg ataaaatgac
    14941 cgcaatcata catgccatat atagagtgtg gtgccctgtt aaaaaaatat atttaaatcg
    15001 agtaaaacga gcgattaaga tattgaacac cattcctgca aacataatca ttgcagtagc
    15061 tgagccatat gttgttaaag ctacagctac aattgcttca ttattcggca caacgccaga
    15121 taaatgaaaa gcatgctcaa acatggtacc aaatggattt aaagaatttt gtacaattcc
    15181 tgcaccacca gatacaacta agaaaccaac aaaggtctta attccacctt taataatatc
    15241 aggtaatttc ttcttctgaa gaactaatcc taaaattgca attaaagcta ctaaaatagc
    15301 tggtgtacta acaatatcca atatgaactt catcatgacg ctagcctcct atataagtcc
    15361 tttttcttca caaagtttag taattaattc tcgtagttca tccatatcaa taatactatt
    15421 taagatacga acatctccaa gatgactagc tgaatcagct agatcacgac caacaatcca
    15481 aatatcagct gcatttggat ctgctccacc taaatcataa tgttcaactt ctacatccga
    15541 aacattcaaa tcactcaata cagattcaat attcatctgt accataaaac ttgaacctaa
    15601 tcctgaacca caagctgtac caatttttaa cattatctaa tcctcctgtt taattatcat
    15661 tttaatatca ttatagtttt ttgatgatat taaagtttga acatgatttt tatctcttaa
    15721 aattgttgtt aaatgtgaca aagcctttaa atgactctca ttatcaatgg ctgcaataca
    15781 aatcaacaat cttacctctt gttctggatt atccaataaa taaatcggtt cttccaaaac
    15841 taacattgac attcctattt cattcacacc ttcatctggc cgagcgtgag gaattgctac
    15901 tcccttccct aaattaataa aaggtccaaa ctcttctact ttttgaatca ttgcctcagg
    15961 gtagttctca gttatcttat cttgatccaa aagcggttta gctgctaaac gaatcgcctc
    16021 cttccatcct aatttttgcg aactaacctg ataggtttct ttggtaataa gttgttctag
    16081 cactggtaca atttcctttc tatcattttt ttggtaaaga taattcttta acgccaatct
    16141 taattccaat tcttgtgtaa taattccata tcttttgaca atattcagga tttgttcaat
    16201 ctcaaaatct ccatactcta aattcggaaa atcttttaac actagttcta ctagttgtat
    16261 tgcttgctct tcagtcatca taaccgaaac tagataattt ggcttttctg tctccacctt
    16321 tatggtagaa aaaaccatat catagtcact actagctttc acctgtaaat catcaatctt
    16381 tgaggttcct ataaactcaa tttgaggaaa taatgctaat agattctctt ttaacatcaa
    16441 tgaagaacta acaccattag gacaaatgat tgctgcttta taccattttt gaggcaaagt
    16501 atctgctttc tttaaataac ctccgaaatg gataacaaaa tatgctgttt cactatcagg
    16561 tatgggattg tcaatagcgt ccatcaaggg catcaaagaa tctttgacta attcaaataa
    16621 atcaggataa tgttctttaa catgcaatac atattcattt gaactaggta ggccgaactt
    16681 taatctatag taagccggta taaggtggcg gcgaagattt tctctcaatc cttccctttg
    16741 tttaaaatgt aacaaagaaa tatcttccat tctacttata atagcctctg ttaattgatt
    16801 aaagtaaacc ggagcaacat ctacttcacc ttcaaagcaa cttgataata aaacggtgat
    16861 atagcgataa tcatcctcag aaaacaccgt atctataatt cccaaatcaa ccactgtatc
    16921 caataaaata gtggttatat cttgaataac aggagatact aatgtctctg aaagacatac
    16981 tctttcaaca tccctttgat acctacacag aatgaatact aaaccgaaaa ggtaaacttt
    17041 taattgatta acaataggta ctagctgtag cttctcataa taatctttaa ctacctgatc
    17101 aatcaaatca taagttaatg aataccccca actggataaa acataatcca aaccccaaat
    17161 ccctatggag gattccagca actcactaac catttgaaaa gctaagcggt gcttattcca
    17221 ctctgaaccg tgtaaagtat aaccttttgc tctactgtac cctagctcca aatcattatc
    17281 taacataatc tttcttaatg attgaatatc agataaggtt gtattcttac ttactttcaa
    17341 aaagtcttgg taatgactat tcgatataaa atctaatcgg caaaaagtgt aaagatagat
    17401 taaagctaag cgagtcgact ttggtaaaac caattcatcc gacttaataa tatctgtcaa
    17461 agactgcttc gtacgatttg ataaactata gcgaccttgc tttttatcca gcactatccc
    17521 tttattagct agataaggca ctaaataatc tattccttct ttgacttcct ttataggtaa
    17581 gctcacctta acagataact catataatga tacctcacaa tgatccatca aagtcatcaa
    17641 aataactagt gctctataat caaacatttc tcttcctttc taactacaat tatagtgt
//
LOCUS       DAVLUM010000043        17462 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLUM010000043 DAVLUM010000000
VERSION     DAVLUM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.043"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            112..621
                     /locus_tag="VYN42_001350"
     CDS             112..621
                     /locus_tag="VYN42_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEV1462414.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILLLE"
     gene            868..1137
                     /gene="rpsO"
                     /locus_tag="VYN42_001351"
     CDS             868..1137
                     /gene="rpsO"
                     /locus_tag="VYN42_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1462415.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            1871..2485
                     /locus_tag="VYN42_001352"
     CDS             1871..2485
                     /locus_tag="VYN42_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1462416.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(2778..3527)
                     /locus_tag="VYN42_001353"
     CDS             complement(2778..3527)
                     /locus_tag="VYN42_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1462417.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            3660..5996
                     /locus_tag="VYN42_001354"
     CDS             3660..5996
                     /locus_tag="VYN42_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1462418.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            6098..6775
                     /locus_tag="VYN42_001355"
     CDS             6098..6775
                     /locus_tag="VYN42_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1462419.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            6762..7559
                     /locus_tag="VYN42_001356"
     CDS             6762..7559
                     /locus_tag="VYN42_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1462420.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            7576..8679
                     /locus_tag="VYN42_001357"
     CDS             7576..8679
                     /locus_tag="VYN42_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1462421.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            8686..8922
                     /locus_tag="VYN42_001358"
     CDS             8686..8922
                     /locus_tag="VYN42_001358"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462422.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVYRTDEVSSKHCFEVVYRTDEVS
                     SKHCFEVVDRTDEVSNHTHGKATLTWFELDFRRV"
     gene            9025..10044
                     /gene="galE"
                     /locus_tag="VYN42_001359"
     CDS             9025..10044
                     /gene="galE"
                     /locus_tag="VYN42_001359"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1462423.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            10046..10999
                     /locus_tag="VYN42_001360"
     CDS             10046..10999
                     /locus_tag="VYN42_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1462424.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(11061..11267)
                     /locus_tag="VYN42_001361"
     CDS             complement(11061..11267)
                     /locus_tag="VYN42_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1462425.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            11319..11795
                     /locus_tag="VYN42_001362"
     CDS             11319..11795
                     /locus_tag="VYN42_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1462426.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            11804..12475
                     /locus_tag="VYN42_001363"
     CDS             11804..12475
                     /locus_tag="VYN42_001363"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1462427.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            12605..12943
                     /locus_tag="VYN42_001364"
     CDS             12605..12943
                     /locus_tag="VYN42_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1462428.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            12946..13575
                     /locus_tag="VYN42_001365"
     CDS             12946..13575
                     /locus_tag="VYN42_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1462429.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            13815..14966
                     /locus_tag="VYN42_001366"
     CDS             13815..14966
                     /locus_tag="VYN42_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1462430.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            15279..16028
                     /gene="truA"
                     /locus_tag="VYN42_001367"
     CDS             15279..16028
                     /gene="truA"
                     /locus_tag="VYN42_001367"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1462431.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            16018..16791
                     /locus_tag="VYN42_001368"
     CDS             16018..16791
                     /locus_tag="VYN42_001368"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1462432.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            16769..17230
                     /locus_tag="VYN42_001369"
     CDS             16769..17230
                     /locus_tag="VYN42_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1462433.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         4950 a         3310 c         3990 g         5212 t
ORIGIN      
        1 ttttcttggt agaaatattt tgataataat taagcaagac tattgacatt gattattaag
       61 agtgtcacaa ttgttgtaac taaaataatt acaacaagag aggtataaaa aatgaaacta
      121 gcagttattg cagcaaatgg acaagcgggg aaggcaattg ttgaagaagc agtcaaacga
      181 ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga gtctattatt
      241 aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc tgttatttca
      301 gcatttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat cgaactattt
      361 aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggagc agaaagtctt
      421 tatatagatg aaacaaaaac gacacgactt ttagatacgc ctgattttcc tgaagaattt
      481 aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa aaataatctc
      541 aactgggctt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa aacaggaaac
      601 tacattctcc tgctagaatg aaaaaggaat aagccagatt agttatgcag attatgctat
      661 tggattggta gatgaacttg aaaaaggtca tcatataaaa gaacgtatct ctttacttga
      721 aaaataataa ctatgagagt attaatgttt gacagaaaat ttaaatcttg gtaaaatagg
      781 gattgtcgta aagacaaata acttcttctt ggttacaggc atgccaacct gtcactcgga
      841 tgaagccaaa taaaaaggag aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc
      901 attgcacaat atgcacgtca cgaaggtgat acaggttcag tagaggttca agttgctgtc
      961 cttacttggg aaatcaacca ccttaacgaa cacatcaaac aacacaaaaa agaccacgct
     1021 acttaccgtg gattgatgaa aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt
     1081 aaaaacgacg ttaaccgtta ccgtgagttg atcaactctc taggacttcg tcgctaattc
     1141 aagatacaag tgcttaggcc gtgttcaatt gagcatatct tgataatgaa gctactctaa
     1201 attgggtagc ttttttgcgt tgtcacctta cctcgctata ctcaagtata atctttggtt
     1261 acggttccta gcactgtaag gtaaaataaa ccagcttttc tcccttcggg gagatttttt
     1321 ttgtttcact gaaagtttcg tacgatcttc gcctcgtcgc ctagtctata aacgatttat
     1381 ctagcaagaa tcatgatgct aagggcgtca aaaatccgta tgaaaatagg gaaatgacac
     1441 agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc cgggctcaaa
     1501 tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca attttggaga
     1561 ctacaaaaac ctcaaacggt atcagctaat tacaccataa aggtgcgcag ttactcggct
     1621 tttcaagccg agtagctgta tgcaagcccc ctagaagagc ccactcttta caaagtaaag
     1681 tatagtatgt tatactttac atggaagtag tcactgaatt ccagttagaa attactttgt
     1741 aactacgttt tgaggaggag taaaatgctt tcctacgttc gacattaccc actagcgata
     1801 gctaaattaa tgtgtctgtg ctctcctaaa atctgctgat ttattactga ctaatacagg
     1861 agtttttttt atgggacaga caatcatatc tgctattggt gtttatattt ccaccagtat
     1921 cgattattta attattttaa ttattttatt tgcacagcta tcacagaata aacagaaatg
     1981 gcatatttat gcggggcaat atctaggcac aggcttactt gtaggggcga gtttagttgc
     2041 tgcttatgtc gttaatttcg tgcctgaaga atggatggtt ggattgcttg gtttaatccc
     2101 tatctattta gggattcgct ttgcaattgt tggagaagat gcggaagaag aagaggaaga
     2161 aattattgaa agattagaac aaagcaaggc aaatcaactg ttttggacag ttacattgct
     2221 gacaattgcg tctggcggag ataatttagg tatctatata ccttattttg cttcgttaga
     2281 ttggtcacag accctcgtgg ccttgcttgt gtttgtaatc ggcataatta tcttttgcga
     2341 gattagtcgg gtgttatcct ctattccgtt aatattcgag acaattgaaa aatacgagcg
     2401 aatcattgtg cccttagtat tcattctact tggactatac atcatgtatg aaaatggcac
     2461 gatagagact tttctgatcg tgtagatttt tttgtttcac taggatttta gcccgagctc
     2521 aaatcagctc tctgattttc agagggcttt ttcattgagt ataaatggac aatcttaaag
     2581 ttactctatt gtagagtggc ttttgatttg attaggagat tcttataaat atagtaaaat
     2641 gaaacaaaaa caggacaaat cgatcaggac agtcaaatcg atttctaaaa atgttttaag
     2701 aagtagagat gtactattct agtttcaatt tgatatataa atgaaaacct tagctgtttg
     2761 gccaaggttc atttcttcta tgcaagttct tctcttttct tatctgggtt ccagatgaag
     2821 cttgcgataa agctaaagat gatggttagg atagcgagga taatagcaag gatgagggca
     2881 gggatgcgga taaaccacca gagtggattt ggttttttat cattgtgcca ttgtttcgtt
     2941 tcttcgtcca gacgttggaa ttctgtttga atacgattgg cgactgtttc aatgccttca
     3001 tcattcattt tcttgatatc tgagatatcg attggatttc caaagttcat atcgacacgt
     3061 tcacggctaa tcaagccctt caaagtcatg ggaccggtgt aggtaaccgg catgatacgg
     3121 accttggcca ttttggcaat cagtgctgcg ccccccttga catcgtttga gtggcggcta
     3181 ccacttggaa acatgatgag agagcggtca ctttttttga gaacgttgat aggatatttg
     3241 atggctgagg cgctgggatt ttcacggtcg atgggaaagg cgccacacat acgaatccac
     3301 caaccaaaga tacggttggt aaagagttct ttttttgcca taaagatgaa ctgttttggc
     3361 ttggtcgcaa aggccatata aacaggatcc caccaggtac ggtgaggcgc aactaaaata
     3421 taattttcat cttgattagg aattttatca gtattatgat agtgagcatt gccattgatg
     3481 gaccataaga gcaatacaac taatccacgc aaataagtat aaaacatgcg atctccttcg
     3541 attgttttct tgttattatt ataccttatc aaaggagggc tggcaaactt ttcccttgac
     3601 tagatgcata tttgggatga aattagaatt ctgttaaaaa aaatgatata atagaattta
     3661 tggataaaaa taagattatg ggattaaccc aaagagaagt caaggaaaga caggctgagg
     3721 gtttggtcaa tgactttacc gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa
     3781 atgtctttac cctttttaac gctttgaact ttgccattgc tttggccctt gcctttgtgc
     3841 aggcttggag caatctggtc ttctttgctg ttatctgctt taacgctttt tctgggattg
     3901 tgaccgagct acgagccaaa cacatggtgg acaagctcaa tctcatgacc aaggaaaagg
     3961 tcaaaaccat ccgtgatggt caggaagttg ctcttaatcc tgaagaatta gtgctaggag
     4021 atgtcattcg tttgtctgca ggagagcaga ttcctagtga tgccttggtt ttggaaggct
     4081 ttgcggaagt caatgaagcc atgttaacgg gagaaagtga tttggtgcaa aaggaagttg
     4141 acggcttact tttgtcagga agtttcctag ccagtgggtc agttttatct caagttcacc
     4201 atgtcggtgc agacaactat gctgccaaac tcatgcttga ggctaagacc gttaaaccca
     4261 tcaactcccg tatcatgaaa tcgctggaca agttggctgg ttttactggg aagattatca
     4321 ttccctttgg tctggctctc ttgctggaag ccttgctttt aaaaggcctg cctctcaagt
     4381 catccgttgt aaactcgtcg acagctcttt tgggaatgtt gcctaaggga attgcccttt
     4441 tgaccattac ttcgctcttg actgcagtga ttaagttggg cttgaaaaag gtcttggtgc
     4501 aggagatgta ctctgttgag accttggcgc gcgtggatat gctctgtctg gacaagacgg
     4561 gcaccatcac ccaaggaaag atgcaggtgg aggctgttct tccactgacg gaaacttacg
     4621 gtgaagaggc tattgccagc atcttgacta gctacatggc ccatagtgag gataagaatc
     4681 caactgccca agccattcgc cagcgttttg tgggagatgt tgcttatcct atgatttcca
     4741 atcttccctt ctccagcgac cgcaagtggg gggctatgga gttagaaggc ttggggacag
     4801 ttttcttagg ggcacctgag atgttgctgg attctgaagt cccagaagcc agggaggcct
     4861 tggagagagg atcacgtgtc ttggtcttag ctctcagtca ggagaaatta gaccatcaca
     4921 aaccacagaa accatctgat attcaggctc tagccttgct ggaaatcttg gaccccattc
     4981 gagagggagc agcagagacg ctggactatc tccgttctca ggaggtggga ctcaagatta
     5041 tctctggtga caatccagtt acggtgtcca gcattgccca gaaggctggt tttgcggact
     5101 atcacagcta tgtagattgc tcaaaaatca ccgatgagga attgatggcc atggcggagg
     5161 agacagctat tttcggacgt gtttcccctc atcaaaagaa actcatcatc caaacgttga
     5221 aaaaagcggg tcatacaacg gctatgacag gggacggggt taatgatatc ttggcccttc
     5281 gtgaggcgga ttgttctatc gtgatggcgg agggagatcc agcaacccgt cagattgcca
     5341 atctggttct cttgaactca gactttaatg atgttcctga gattctcttc gagggtcgtc
     5401 gcgtggtcaa taacattgcc cacatcgccc cgattttctt gataaagacc atctattcct
     5461 tcctgttagc agtcatctgt attgccagtg ctttactagg tcggtcagag tggattttga
     5521 ttttcccctt cattccgatc cagattacca tgattgacca gtttgtggaa ggtttcccac
     5581 cattcgtttt gacttttgag cgaaatatca aacctgtcga gccaaacttc ctcagaagat
     5641 ccatgcttcg tgccctacca agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa
     5701 tctttggaac gagtcaaggt tggtctgagt tagaaatctc aactctcctc tattatctct
     5761 tggggtcaat tggtttctta tccgtattta gagcctgcat gccattcact ctatggcgag
     5821 tcctcttgat tgtctggtca gtaggaggct tcctagccac agctctcttc ccaagaatcc
     5881 aaaaactgct tgaaatttca accttgacag aacaaacgtt gcctgtttat ggtgtcatga
     5941 tgttggtctt tacagtgatt ttcatcctga ctagtcgcta tcaagctaga aaataaagaa
     6001 agactgcaat ctgtggattg cagttttttt aggtacaaga ttgccagccg aaatgtggta
     6061 taataagagg taatagagtt ttggaaagtg agagaagatg atttcaaaga gattagaatt
     6121 ggtagcttcc tttgtgtcac agggggctat tttactagat gtgggaagtg accatgctta
     6181 tctgcctatc gagttggttg agagaggcca aatcaaaagc gctattgcag gtgaggtggt
     6241 ggaaggtccc tatcagtctg cggttaaaaa tgttgaggct cacggcctaa aggagaaaat
     6301 ccaagtccgt ttagccaatg gcttggcagc ttttgaagag actgaccaag tgtctgtcat
     6361 taccattgct ggcatgggtg gtcgtttgat tgctaggatt ttagaagaag gtttggggaa
     6421 gttagctaat gtagagcgtt tgatcctcca gcccaataat cgtgaagacg acttgcgtat
     6481 ctggctacag gatcatggat tccagattgt agcagaaaga atcttagaag aagctggaaa
     6541 gttttatgag attttggtgg tggaagcagg acaaatgaag ctatcagcca gtgatgttcg
     6601 ctttggtccc ttcttgtcca aagaagtcag tccagtattt gtccaaaaat ggcaaaaaga
     6661 agctgagaag ctagagttcg ccctcggaca aatcccagaa aaaaatctgg aagaacgtca
     6721 agttctagta gataagattc aagctatcaa ggaggtgctc catgttagca agtgaagtga
     6781 tccaagctta tgaagccttt tgccctcagg aattttctat ggagggagac agctgtggtc
     6841 tgcaaattgg cactttagac aagggtatcc aaagggtcat ggttgccctc gatattcgtg
     6901 aagagacggt ggctgaagcc attgaaaagg gtgtagactt gattatcgtc aagcacgcgc
     6961 ctatctttcg tcctatcaag gacttgcttg ccagccgtcc gcaaaatcag atttacatcg
     7021 acctgattaa gcatgacatc gcagtttatg tcagccatac caatattgat atcgttgaaa
     7081 atgggctcaa tgactggttt tgtcagatgc taggaatcga ggagacgact tatctgcagg
     7141 aaacaggtcc agaacgtgga attggacgta ttgggaatat tcagcctcag acattttggg
     7201 aattggccca acaggtcaag caagtctttg acctagatag ccttcgaatg gtgcattatc
     7261 aagagaatga tttgcagaag cctatttcaa gagtagcaat ttgtggtgga agcgggcagt
     7321 ctttctataa ggatgctttg gcaaaggggg cagatgtcta tatcactggt gatatctact
     7381 accatactgc tcaggatatg ctgtctgatg gcttgttagc attggatcca ggtcactata
     7441 tcgaagtgct ttttgtggaa aaaatcgcag cactccttac tcaatggaaa gagaaaaaag
     7501 gctgggaact agagatttta cctagtcaag catcgaccaa tcctttccgt catatctagt
     7561 tagaaagtga agacaatgaa aaaagttgcc attattggag caggaattgt gggagcaaca
     7621 gctgcctact acctctcgag agaaagtgac ctagaggtga ccgtttttga ccatgagcaa
     7681 ggtcaagcca ccaaggccgc agcaggaatt atcagtcctt ggttttccaa acgccgtaat
     7741 aaagcctggt acaagatggc gcgcttgggg gctgactttt atgtggattt attagctgat
     7801 ttagagaaat caggacaaaa aatcgacttt taccagcgtt cgggagtctt tctcttgaaa
     7861 aaggatgaat ccaagttgga agaactttat caactggccc tccagcgcag agaagaatct
     7921 cccttgatag ggcaattagc cattctggac caagcttcag ctaatgaatt attccctggt
     7981 ttgcagggat ttgaccgcct gctctatgct tctggtggag cgagagtaga tggccaactc
     8041 ttggtaactc gtctgctaga agccagtcat gtcaagctgg tcaaagaaaa agtgactctg
     8101 acactcttat catcaggcta ccagattggc gaagaggtgt ttgatcaggt tattttggca
     8161 acgggagctt ggttggggga catgttagag cctttaggtt atgaagtgga tgtccgtcct
     8221 caaaaaggac aactacgaga ttatcagctt gcccaagaca tggaagatta ccctgttgtc
     8281 atgccagaag gggagtggga tttgattccc tttgcaggtg ggaaattatc cttgggcgct
     8341 acccatgaaa atgacatggg atttgatttg acggtagatg aacccttgct ccaacaaatg
     8401 gaggaggcgg ccttgcctca ttacccagtt ttagctagag cgacttcaag ggctgagcgt
     8461 gtgggaatcc gtgcctatac cagtgatttc tctcccttct ttgggcaggt gccagaattg
     8521 gcaggtgtct atgtagccag tggactaggt tcatcaggcc tcacaactgg tcctatcatt
     8581 ggttaccatc tagcccaact gatccaagac aaggagttga ccttggaccc tctaaattac
     8641 ccaattgaaa actatgtcaa acgagtaaaa agcgaataat actcaatgaa aatcaaagaa
     8701 caaactagga aactagccgc gggttactca aagcactgct ttgaggttgt gtatagaact
     8761 gacgaagtca gctcaaaaca ctgttttgag gttgtgtata gaactgacga agtcagctca
     8821 aaacactgtt ttgaggttgt agatagaact gacgaagtca gtaaccatac ccatggcaag
     8881 gcgacgttga cgtggtttga attggatttt cgaagagtat aagcatttta ctgaaatttt
     8941 atcaggtagt ttaggatggc aaatgacatt ccctgtcaaa aatggtaaaa taagaaaaaa
     9001 taatctgaga atcgaggaaa aaagatgcaa gaaaagattt tggtaactgg tggtgccggt
     9061 tttattggaa cccacactgt tattgaattg atccaagcag gccatcaagt tgttgtggtg
     9121 gataatcttg tcaatagcaa tcgtaagagt ttagaagttg ttgaaagaat cacaggagtt
     9181 gagattcctt tctatgaggc agatattcgt gacacagtta ccctcagaga tattttcaag
     9241 caggaagaac cgactggtgt cattcacttt gctggtttga aggctgttgg cgaatcaaca
     9301 cgtatccctc ttgcctacta tgacaacaat atcgctggaa ctgtcagcct tttgaaagcc
     9361 atggaagaaa acaactgtaa aaacatcatc ttcagttctt ctgcgacagt ttacggggat
     9421 ccgcacacag tgcccatctt ggaagatttc ccactttcag tgaccaaccc atacggtcgt
     9481 accaagctca tgctagagga aattttgacc gatatttaca aagcagactc agaatggaat
     9541 gttgtcttgc ttcgttactt taacccaatc ggagcccatg agagtggtga tttgggagaa
     9601 aatccaaacg gtattccaaa caatctcttg ccatatgtga ctcaagtagc cgttggaaaa
     9661 ttagagcaag tgcaagtgtt tggagacgat tacgatacgg aagatggaac aggtgttcgt
     9721 gactatatcc acgttgtcga tttggctaag ggtcacgttg cagctttgaa aaaaatccaa
     9781 aaaggttcag gactaaacgt ttataacctt ggaactggta aaggttactc agttcttgaa
     9841 attatccaaa acatggaaaa agcggtggga cgtcctattc cttaccgcat cgtagaacgt
     9901 cgcccaggtg atatcgctgc ctgctactca gacccagcaa aagctaaagc agaactcggt
     9961 tgggaagcag aactcgacat cacccaaatg tgtgaagacg catggcgttg gcaaagcaag
    10021 catccaaatg gatttgaaga ctaagatgat gatttcaatc atcgtccctt gtttaaacga
    10081 agaggaagta cttcctcttt tttatcaggc tctggaagct ttacttccag atttggaaac
    10141 agaaatcgag tatgtctttg tcgatgatgg atcaagtgat gggaccttgg aactcttaaa
    10201 ggcctatcgg gagcaaaatc cggcagtcca ttatatttct ttctctcgaa attttggcaa
    10261 agaagcagcc ctttatgcag gcttgcaata tgcgacagga gatttggtgg tggtgatgga
    10321 tgcagacctc caagatcctc ctagtatgtt gtttgagatg aaaaatgtac tagacaaaaa
    10381 tgtagacttg gactgcgttg ggacacggag aactagtcgg gagggagaac ccttctttcg
    10441 cagtttctgt gctgttctct tttatcgcct catgcaaaaa atcagcccag tagctctgcc
    10501 gtcgggtgtc cgtgattttc gtatgatgag aaggtctgtg gtcgatgcca ttttaagctt
    10561 gactgagtcc aatcgttttt ctaagggact ctttgcctgg gtcggcttta aaacccacta
    10621 tctggactat ccaaatgtcg aaaggcaggc tggcaagacc agttggagtt ttaggcaact
    10681 ctttttttac tccattgaag ggattgttaa tttttcagat ttccctttga ctatagcctt
    10741 tgtagctggt ctcctatctt gttttctttc tctgctgatg accttttttg ttgtggttcg
    10801 gaccctcatt ttgggcaatc cgacatctgg ttggacctct ctgatggctg ttattctctt
    10861 tcttggaggc attcaactct tgaccattgg gattctcggt aagtatatca gtaagattta
    10921 tttagagact aaaaaaagac cactttatct tatcaaagaa aaaagtgacc ttcctgattt
    10981 tacagaaaaa ataaagtgaa aagactataa ttttacatgg aaatgtgcta aactagaggg
    11041 agtggattat cgccattgat ttaggcttcc tggtttccaa tcagggcgcg agttgggcaa
    11101 tttttaacag cctctaagac atcctgacta ggagaaattt ctttttccag ttggtcaggg
    11161 tcatcgtaaa aacgcacgat tccattatcg tggtaatcaa ataaatcaga ataagtttgg
    11221 caaagtccac aggcgataca tcgttcaggt ataagtgtga ttttcatgtt catatttata
    11281 ttgtaataag aaaagtaaaa aaaaacaagg agtaaggtat ggcaaaagaa ccgtggcaag
    11341 aagatattta tgatcaagaa gaatcaagag cagggcgtcg gcatcgaaac cacggagggg
    11401 ctgataggat ggctaatcgt attttgacga tcctagctag tattttcttt gtaattgtgg
    11461 tggtgatggt catcgttctc atctatctat catcgggggg gagtaatcgc acagcagcct
    11521 taaaagactt tcatgattct gatgcaagtg tagtacaaat ctcatcttca agcagttctc
    11581 agcctgagca gagttcagag ccagaatcta cttctagtag ttcagaagaa gctgctaatc
    11641 ctgaaggaac gattaaagtt ctcgcaggag aaggggaagc agctattgcc gctcgtgcag
    11701 gaatctccat tgctcagtta gaggccttga atcctgggca catggctaca ggatcttggt
    11761 ttgctaatcc aggtgatgtt ataaaaataa aataggagcc gatatgaaaa caattcaaat
    11821 tgctattgat ggtcctgctt ccagcggtaa gagtacggtc gcaaagatta ttgctaagga
    11881 ttttgggttc acctaccttg atacaggagc tatgtatcgt gcagcgacct atatggctct
    11941 taagaaccaa ttaggagttg aagaagtcga agcccttcta gccttgttgg accaacatcc
    12001 aatcagcttt ggacgttcag aaactggaga ccagcttgtt tttgtaggag atgtggatat
    12061 tacccatcct atccgtgaaa atgaagtgac caatcatgtt tctgctattg cagcaattcc
    12121 tgaagtgcgt gagaaactgg tttctctcca acaagaaatt gcccagcaag gcgggattgt
    12181 catggatggt cgcgatattg gaactgttgt attgccacaa gcagaattga aaattttcct
    12241 agtagcttct gttgatgaga gagcagagcg tcgttacaag gaaaatattg ccaagggaat
    12301 tgaaacagac cttgaaaccc taaaaaagga aattgctgcg cgtgactaca aggatagtca
    12361 tcgtgagact tctcctctca aacaagcaga ggatgctgtc taccttgata caactggttt
    12421 gaacattcaa gaagtagttg aaaaaatcaa agcagaagct gaaaaaagaa tgtaaatgta
    12481 gaaaagccga tagattgata tcggtttttt ctaaatttgt caaaatgctg attttagggt
    12541 ataatagttg ctgttcgaga aattttgatt ttcaaagaat agtgaatgat gataaggaga
    12601 aatcatgaac aatttaccaa attgtccaaa atgtaactca gagtatgtct acgaagacgg
    12661 tgccctactg gtttgcccag agtgtgctca tgagtggaat cctgctgaag ttgcagaagt
    12721 agaagaaggt cttgtcgcta tcgatgccaa cggaaataaa ttggctgatg gtgatacagt
    12781 aactctcatc aaggacttga aagtaaaagg tgcgccaaaa gatttgaaac aagggacgcg
    12841 cgtgaaaaat atccgcatcg tagaaggcga ccacaatatc gactgtaaga ttgatggttt
    12901 tggtgccatg aaacttaaat cagagtttgt gaggaagatt taagcatgtc aaaacactat
    12961 aaacttgtat tttatagccg tatcttcttg tttctagcgg cttttacggg agtttatctt
    13021 gaaattacta ggcatggtgg ttttgggatg cttctctatt acacggttct gtccaacctc
    13081 ttggtaacta tttttaccct ttatcttcta aaggttatga gccgtgtagg tgaaaattgg
    13141 caaaggccaa gtctcttgcg cttaaaaggt ggggtcacca tgagtatcat gattacctgt
    13201 gtgatttacc atttcctctt ggcgcccatt gcgactaatt tctataccct agaaaatttc
    13261 ctttgccact atatcgttcc catctggttt ttagcggata ccctcttttt tgacaaacag
    13321 ggtcaataca agatttggga tccagcagtg tggaccattt taccctttct gtatatgatg
    13381 tttgctcttt ttaatggctt ggttctaaaa ctcaatattc caaatgccaa ggataatcct
    13441 ttcccttact tctttttgaa tgtgaacaag ggttggaatg ttgtgtttaa gtggtgtctg
    13501 attatctttg ttgcctatat ggtagcagga tttattttct actttatcaa gcaaatcaag
    13561 agaaagtcat cctaatactc ttcgaaaatc tcttcaaacc acgtcagttt ccatctgcaa
    13621 cctcaaaaca ctgttttgaa caacctgcgg ctagcttcct agtttgctct ttgattttca
    13681 ttgagtataa gatacaaggg attcattttc gaatttaaga aggagtctac aaaccaatga
    13741 ggcttcttct tttcttgctt atttgataac tatcaaaaaa gtagaagatt aagagaaata
    13801 tagaaagaga tttcatgaaa caatttttag aacgggccag cattttggct ctctccctcg
    13861 ttttgattac ctccttttcc atttcgagtg ccctaccagc catgtttgac tattatcagg
    13921 gttattctaa ggaacaaatt gagctcttgg tgagcttgcc ttcctttgga atcatgatga
    13981 tgttactgct aaatggtttc ttagaaaaaa tatttcctga gcgcttacag attagtttgg
    14041 gcttgctgat tttatcattg agcggtacag ctcccttctg gtaccaagcc tatccctttg
    14101 tctttggaac acggcttctc tttggtttgg gtcttgggat gatcaatgcc aaggccattt
    14161 ctattatcag tgaacgctac caaggaaaaa ggcgaattca gatgttaggg ctacgcgctt
    14221 ctgcagaggt cgttggagct tctctcatta ccttggccgt cggtcagttg ttggcctttg
    14281 gttggacagc tatctttcta gcctatagtg ctggattttt ggtgctgccc ctttatctgc
    14341 tctttgtccc ttatggaaaa tcaaagaaag aagtcaagaa aagagcgaag gaagcaagtc
    14401 gtttaactcg agaaatgaaa ggcttgattt ttaccttagc tatcgaagcg gcagttgtag
    14461 tttgtaccaa tacagctatt accatccgta ttccaagttt gatggtggaa agaggattgg
    14521 gggatgccca gttatctagt tttgttctta gtatcatgca gttgatcggg attgtggctg
    14581 gggtgagttt ttctttcttg atttctatct ttaaagagaa actgctcctc tggtctggta
    14641 ttacctttgg cttggggcaa atcgtgattg ccttgtcttc atccttgtgg gtggtagtag
    14701 caggaagtgt tctggctgga tttgcctata gtgtagtctt gacgacggtc tttcaacttg
    14761 tctctgaacg aattccagct aaactcctca atcaagcaac ttcatttgct gtattaggct
    14821 gtagtttcgg agcctttacg accccatttg ttctaggtgc aattggctta ctaactcaca
    14881 atgggatgtt ggtctttagt atcttaggag gttggttgat tgtaatctct atctttgtca
    14941 tgtacctact tcagaagaga gcttaggatt gattcctaag tttttctttt gatactcaat
    15001 gaaaatcaaa gagcatagtt gattgagttt ggaatagtac gctgtagctg ctaaaatatt
    15061 tctagaaatt aatttgactt ttctaataga gttattcata tcttatttca atctactata
    15121 gaaagctagc cgcaggttgc tcaaaatagt gttttgaggt tgcagatgga aactgacgtg
    15181 gtttgaagag attttcgaag agtatgagat ttttataccc atacaatatt tgttttaggt
    15241 ccttgtttac agactaattt cttgataaaa tagaggttat gacgagatat aaagcaacta
    15301 tttcctatga tggttatgcc tttgctggct ttcagcgcca gtctcatgcg cgtagcgttc
    15361 aggaagaaat tgaaaaaacc ttgaccagat taaataaagg gcaaaccatt actgttcacg
    15421 gtgctggtag aacagatagt ggggttcatg ccctgggaca ggtcattcat tttgacctgc
    15481 cttatcagat ggatgaggag aaactccgtt ttgccttgga tacccagtct cctgaagata
    15541 ttgatgtgat ttcgattgag cttgtggcag atgattttca ttgccgttat gccaaacata
    15601 gcaagaccta tgagtttatt gtggatagag gacgtcccaa aaatcctatg cgccgtcact
    15661 atgccaccca ctttccctac ccactcgatg tggaacgaat gcagattgca atcaaaaagc
    15721 tagagggaac ccatgatttt accggtttta cagcctctgg gactagtgta gaggataagg
    15781 ttcgcaccat cacagaagct agtttaatag tcgatgagac aggacaattt ttgaccttta
    15841 ccttttcagg aaatggtttc ttgtataaac agattcgcaa tatggtgggg actcttctca
    15901 aaatcggtaa caaccgcatg ccagtagagc agattgctct catcttggag aagaaggaca
    15961 ggcaacttgc aggtcccact gcagcaccaa atggtttgta tttaaaggag attcgttatg
    16021 aagaataatc gtattttagc actttctgga aatgatattt ttagtggtgg tggactgtca
    16081 gctgatttgg ctacctatac cttgaacggc ttgcatgggt ttgtagcagt gacttgtttg
    16141 acagccttga cagaaaaagg atttgaagtc tttccaactg atgataccat ttttcaacat
    16201 gaattagata gcttgcgtga tgtggaattt gggggaatta agattggtct tctccctact
    16261 gtcagtgtgg ctgagaaggc cttggacttt atcaaacaac gcccaggagt acctgtggtg
    16321 ttggatcctg tcttggtctg caaggaaacg catgatgtag ctgtcagtga gctctgccaa
    16381 gagttgattc gctttttccc ttatgtcagt gtgattacgc ctaatctccc agaagcagaa
    16441 ttattatccg gtcaggaaat taaaaccttg gaagacatga aaactgcagc gcagaaattg
    16501 catgatttag gagcgccagc agtcattatc aagggaggca atcgtcttag tcaggacaag
    16561 gctgtggatg tcttttatga tggacagacc tttactatcc tagaaaatcc agttatccaa
    16621 ggccaaaatg ctggtgcagg ttgtaccttt gcctctagca ttgccagtca cttgattaaa
    16681 ggtgataaac ttttgccagc agtagaaagc tctaaggctt tcgtttatcg tgctattgca
    16741 caagcagatc agtatggagt aagacaatat gaagcaaaca aaaacaacta aaatcgccct
    16801 tgtatcccta ttaaccgccc tttctgtggt tctaggttat ttcttaaaaa tcccaacacc
    16861 tacaggaatt ctaactcttt tagatgctgg tgtcttcttt gcggcctttt actttggtag
    16921 tcgtgaagga gcggtagtcg gaggactagc aagtttcttg attgacctct tatcaggcta
    16981 ccctcagtgg atgttcttta gcttggtcaa ccatggcttg cagggatttt tcgcaggatt
    17041 taaaggaaaa agtcagtggt taggccttat tttagcaact attgccatgg taggaggcta
    17101 cgccttgggt tctactttga tgaatggctg ggcagcagcc ctcccagaaa ttctaccaaa
    17161 tttcatgcaa aatatggtag ggatgattgt aggatttatt cttagtcaaa gtatcaagaa
    17221 gattaagtaa tactcttcga aaatctcttc aaaccacgtc agcttccatc tgcaacctca
    17281 aaacactgtt ttgagcagcc tgaggctagc tttctagttt gcactttgat tttcattgag
    17341 tataaagagg ttgagtaaaa agtatttcaa ataagaaaaa cgcatagtat caggtgttga
    17401 atgaactgcc ccccaaaagt tagacagaaa aaatctaact tttggggtgt tttattatga
    17461 aa
//
LOCUS       DAVLUM010000044        17440 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLUM010000044 DAVLUM010000000
VERSION     DAVLUM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.044"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            302..1348
                     /gene="pheS"
                     /locus_tag="VYN42_001370"
     CDS             302..1348
                     /gene="pheS"
                     /locus_tag="VYN42_001370"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1462434.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1348..1857
                     /locus_tag="VYN42_001371"
     CDS             1348..1857
                     /locus_tag="VYN42_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462435.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1934..4339
                     /locus_tag="VYN42_001372"
     CDS             1934..4339
                     /locus_tag="VYN42_001372"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1462436.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4407..5408)
                     /locus_tag="VYN42_001373"
     CDS             complement(4407..5408)
                     /locus_tag="VYN42_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1462437.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5564..5979
                     /locus_tag="VYN42_001374"
                     /pseudo
     CDS             5564..5979
                     /locus_tag="VYN42_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6105..6371
                     /locus_tag="VYN42_001375"
     CDS             6105..6371
                     /locus_tag="VYN42_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462438.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6632..8881
                     /gene="metE"
                     /locus_tag="VYN42_001376"
     CDS             6632..8881
                     /gene="metE"
                     /locus_tag="VYN42_001376"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1462439.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8945..9811
                     /gene="metF"
                     /locus_tag="VYN42_001377"
     CDS             8945..9811
                     /gene="metF"
                     /locus_tag="VYN42_001377"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1462440.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10496..12709
                     /gene="pnp"
                     /locus_tag="VYN42_001378"
     CDS             10496..12709
                     /gene="pnp"
                     /locus_tag="VYN42_001378"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1462441.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12725..13342
                     /gene="cysE"
                     /locus_tag="VYN42_001379"
     CDS             12725..13342
                     /gene="cysE"
                     /locus_tag="VYN42_001379"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1462442.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13354..14238
                     /locus_tag="VYN42_001380"
     CDS             13354..14238
                     /locus_tag="VYN42_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462443.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGVRDSEV"
     gene            14325..15668
                     /locus_tag="VYN42_001381"
     CDS             14325..15668
                     /locus_tag="VYN42_001381"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1462444.1"
                     /translation="MIKIYDTMSRDLREFVPIENGKVKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15661..16047
                     /locus_tag="VYN42_001382"
     CDS             15661..16047
                     /locus_tag="VYN42_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1462445.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16051..16935
                     /locus_tag="VYN42_001383"
     CDS             16051..16935
                     /locus_tag="VYN42_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1462446.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(16982..>17440)
                     /locus_tag="VYN42_001384"
     CDS             complement(16982..>17440)
                     /locus_tag="VYN42_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1462447.1"
                     /translation="RYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLK
                     HHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPY
                     SNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5172 a         3381 c         3986 g         4901 t
ORIGIN      
        1 gataagaata agctaacaag cagaagtaag ataggtcttg caagaatggt aaaaatctga
       61 taaactaagt agtaattgaa taggaatctg aaagactagt agcccaaggg aagtatatca
      121 gggaggagag ccgtgactgc aagctctcta tatgaaagct gggtgaattc acttgcgcat
      181 ggatttagaa atgaaggtct gacttgtcag atgaaaacgg atggtaccgc gtgtcaacgc
      241 tccgagtgga gtttttggca tgtggttttc tttttatcta cgagagactg atggaggaaa
      301 tatgtcaact attgaagaac aattaaaagc gcttcgcgaa gaaacgctga ctagcttgaa
      361 gcagattact gctggaaatg aaaaagagat gcaagatttg cgtgtctctg tccttggtaa
      421 aaagggttcg ctcactgaaa tcctcaaagg gatgaaagat gtttctgctg agatgcgtcc
      481 aatcatcggg aaacacgtca atgaagctcg tgatgtcttg acagctgctt ttgaagaaac
      541 agctaagctc ttggaagaaa agaaagtcgc ggctcaactg gctagcgaga gtatcgatgt
      601 gacgcttcca ggtcgtccag ttgcgactgg tcaccgtcac gttttgacac aaaccagtga
      661 agaaatcgaa gatatcttca tcggtatggg ttatcaagtc gtggatggtt ttgaagtgga
      721 gcaagactac tataactttg aacgtatgaa ccttccaaaa gaccacccag ctcgtgatat
      781 gcaggatact ttctatatca ctgaagaaat cttgctccgt acccacacgt ctccagttca
      841 ggcgcgtgct atggatgccc atgatttttc taaaggtcct ttgaagatga tctcgccagg
      901 gcgtgtcttc cgtcgcgata cggacgatgc gacccacagt caccaattcc accaaatcga
      961 aggcttggta gttgggaaaa atatctctat ggctgatctt caaggaacgc ttcagttgat
     1021 tgtccaaaaa atgtttggtg aagagcgtca aattcgtttg cgtccatctt actttccatt
     1081 cacagagcca tctgttgagg tggatgtttc ttgcttcaaa tgtggtggag aaggctgtaa
     1141 cgtatgtaag aaaacaggtt ggatcgaaat tatgggggcc ggtatggttc acccacgtgt
     1201 ccttgaaatg agtggtatcg atgcgactgt atactctggc tttgcctttg gtcttggaca
     1261 agagcgtgta gctatgctcc gttatggaat caacgatatc cgtggattct accaaggaga
     1321 tgtccgcttc tcagaacagt ttaaataatg attagaaaag tagaaatggc agatgttgag
     1381 gtgttggcta aaattgccaa acaaaccttt cgtgaaacct ttgcgtatga taatacggaa
     1441 gagcagttac aggaatactt tgaagaggct tatagtctga aaactttgtc aactgagttg
     1501 ggaaatcctg actctgaaac ctatttcatt atgcatgagg aggagatagc tggttttctc
     1561 aaagtcaact ggggaagtgc tcaaactgag agagaattag aggacgcttt tgaaattcaa
     1621 cgcctctatg tgctacaaaa attccaagga tttggactag gtaagcaact gtttgaattt
     1681 gctcttgaac ttgctacaaa aaatagtttt tcttgggctt ggttaggtgt ttgggagcat
     1741 aatacaaaag ctcaagcgtt ttataaccga tatggttttg aaaaatttag ccaacatcat
     1801 tttatggttg gtcaaaaagt agatacggat tggttactga gaaagaaatt aaggtaagaa
     1861 gatgattctt ctattgaaat gataggaaag gaaaagaact agagtgacaa ctgtcattct
     1921 ggagaactaa attatgcttg tatcttataa atggttaaaa gaattggtgg acattgatgt
     1981 gccatcacag gagttggctg aaaaaatgtc aaccacaggg atcgaggtcg aaggtgtcga
     2041 atcaccagct gccggtcttt caaaaattgt cgtcggtgag gtcttgtctt gcgaagatgt
     2101 gccagagact cacctccatg tttgtcaggt taacgttggc gaagaagaag cccgtcagat
     2161 cgtttgtggt gccccaaatg tgcgtgctgg gatcaaggtc atggtggctc ttccaggagc
     2221 tcgtatcgct gataactaca aaatcaaaaa aggaaaaatc cgtggtttgg agtcacttgg
     2281 aatgatctgt tcacttggtg aattgggaat ttctgactca gttgtgccta aggaattcgc
     2341 agatggcatc caaatcttgc ctgaagatgc cgtgccaggt gaggaagtct tttcttacct
     2401 agacttggat gatgaaatca tcgaactttc catcacacca aaccgtgcag atgccctttc
     2461 tatgtgtgga gtggctcacg aagtggcagc catctatgac aaggcagtca actttaaaaa
     2521 atttactcta acagaaacta atgaagctgc ggcagatgcc ctttctgtca gcattgagac
     2581 agacaaggcg ccttactatg cagctcgtat cttggacaat gtgactatcg caccaagtcc
     2641 acaatggttg caaaaccttc tcatgaacga aggcatccgt cccatcaata acgttgtaga
     2701 cgtgacaaac tacatcctgc tctactttgg tcaacctatg catgcttttg acttggacac
     2761 atttgaaggg actgacatcc gtgtgcgtga agcgcgtgat ggtgaaaaat tagtgaccct
     2821 ggacggtgaa gaacgagact tggctgagac agacctcgtg attacagttg ctgacaaacc
     2881 agtagccctt gccggtgtta tgggtggtca ggctacagaa atttctgaaa aatctagtcg
     2941 tgttatcctt gaagctgctg tttttaatgg caaatctatc cgtaagacaa gtggtcgcct
     3001 gaaccttcgt tctgagtcat cttctcgctt tgaaaaagga attaatgtgg caacagttaa
     3061 tgaagccctt gatgcggcag ctagcatgat tgcagagctt gcaggcgcga cggtgcgtaa
     3121 gggtatcgtt tcagcgggtg agcttgatac ctctgatgtg gaagtttctt caacccttgc
     3181 tgatgttaac cgtgtcctcg gaactgagct gtcttatgct gatgtagaag acgtcttccg
     3241 tcgtcttggc tttggtcttt ctggaaatgc agacagcttt acagtcagcg taccacgtcg
     3301 tcgttgggat atcacaatcg aagctgatct ctttgaagaa atcgctcgta tctatggata
     3361 tgaccgcttg ccaaccagcc ttccaaaaga cgatggtaca gctggtgaat tgactgtgat
     3421 acaaaaactc cgccgtcaag ttcgtaccat tgctgaagga gcaggtttga cagaaatcat
     3481 cacctatgct ctgacaactc ctgaaaaagc agttgagttc acagctcaac caagtaacct
     3541 tactgaactc atgtggccaa tgactgtgga tcgttcagtc ctccgtcaaa atatgatttc
     3601 agggatcctt gataccgttg cctacaacgt ggctcgtaag aataaaaact tggcccttta
     3661 tgagattgga aaagtctttg aacaaacagg taatccaaaa gaagaacttc caaatgagat
     3721 caacagcttt gcctttgcct tgacaggctt ggttgctgaa aaagatttcc aaacagcagc
     3781 agttccagtt gatttcttct atgctaaggg aatccttgaa gccctattta ctcgtttggg
     3841 actccaagta acctatacag caacatctga aatcgttagc cttcatccag gtcgtacagc
     3901 cgtgatttca ctcggtgacc aagttcttgg tttccttggc caagtgcatc cagtcactgc
     3961 caaggcttac gatattccag aaacgtatgt agctgagctt aacctttcag ccatcgaagg
     4021 ggcgctccaa cctgctgttc catttgtgga aatcaccaaa ttcccagcag tcagccgtga
     4081 cgttgccctt ctcctcaagg cagaagtgac tcaccaagaa gttgtagatg ctatccaagc
     4141 tgccggcgtg aaacgtttga cagatatcaa actctttgac gtcttctcag gtgaaaaact
     4201 gggacttggt atgaagtcaa tggcttatag cttgaccttc caaaatccag aagacagctt
     4261 aacggacgaa gaagtcgcac gctatatgga aaaaatccaa gcgtctctcg aagaaaaagt
     4321 caatgcagaa gtgcgttaaa cgatagtagg atacaaattc cccctctagt ttatgaacat
     4381 tagaggggtg attttatata aaataattaa aatgtgattt ctgtaaaaat acatctatga
     4441 tcagagtttt gaaaacttac aatgtctaaa tctttaacat agtagtggtt tttaggcaat
     4501 aaaatatgat ctattgttgc attaaaaagt tttggacttt ggctattcca agttcctctt
     4561 tcaaaaggtg gcagtgcatt taatgcgtcc ctatgagagc ttatttttgc aagtgctcca
     4621 tgacgcatag ttgcattaaa atcacctgca ataatagcct ttggatattt tgaagccaat
     4681 tgattatgaa tgatgtttaa gtcttgcttc cagatttcca ttaaacctgg cagaggagga
     4741 gcagtatgca aggcaatgat atctggtata ttttgttttc tcgaatgtaa tacaattgtc
     4801 ccgaaccgtg ttgtatgaaa agttttagct tctgtataga aaccataact tttcttgaca
     4861 atcacagtca caggagctat tccactattg gtaggtggag aagtgaaaat atcatagttg
     4921 gccatagaaa gtccaacttg atgaaacaat agtttgattc tctggttttc ttgctcacct
     4981 ctgatattgg tagctagttc agggaatata gccatatcgg cgtcaaaatg gctaaaaatt
     5041 cgctcaatat gttgtgcttc tatttgatta gcgacgttcc aagttactaa ttttaaggtt
     5101 ttagtcttat ttgatgcaga agaaagggtt ttatctgttc cgaataatag taatatgagc
     5161 gatagtaaga gcaaaatgcc agagtaaaac cgtatttgtt tatttttctt gtaaaaagat
     5221 aggaaaaaaa ataagaaact taaaatagca gccatagttg cagtagctaa ggggaaggca
     5281 taaatctgtg ccaagatagg ttgggtagat agccaaatgt taagattaga agatgggaaa
     5341 aaagaataag ttatgatagg gatagaaaag agaatgaccg aaagggcaga gagaaatgtt
     5401 ttaatcattg tgtgagtacc tcaatttgca atggttgctc ggagctaatg tgactttgtg
     5461 actttacttg attgatattc tttttcttgt cttcctcata gattaagtac aacccaagta
     5521 aaaaaagtcc aatttaagat tgaaatgatt aaaaggcaca gaaatgcaag acaattatac
     5581 tacaaaaggc aaacatttga caatcgatag ccgtcgctta atcgaacgat ggaaaaaaga
     5641 aggaaaatca aatagagaaa ttgcctctct acttggaaaa gctcctcaaa ctatccacac
     5701 tgaaatcaag cgtgggacag tccgacaatg tcttggaaaa gggcgcttca aagagattta
     5761 ttctgccgac tacgctcaac agtcttaaga aactaaagga aaagattctc cactatacat
     5821 aaccaaaaac ataaccaaaa attttcgcct gaaatgatgg tgatggctaa aggggttaac
     5881 gtgggaattt caaccattta ctattggatt catcgtggaa aattggggtt aagcaagcag
     5941 gaactgcttt atcctagaaa aggaaaatcg cttaagaaat aggctagcac caactttaaa
     6001 cccactggtc aatctatcga atcataattc gctcattttt ttaaaaatac atagacgtaa
     6061 aaaaaagagg gttaagtgat gaagaatagt gctattggga gtaattggaa ggatgtccat
     6121 ctgagctctt tagcaaggag gaaatccttg aaagtgatat gcgagtggct atcatgagcg
     6181 agttgattga ggctaggtat gaacaaggaa tcagtcagaa aaagctggaa gaagtcagtg
     6241 gaataagcca gcctgtcata gctaggatgg agacaggaaa gactagtcct cagttggata
     6301 cagtcttaaa agtcctagcc agtttaggaa agacactagc aatcgtccca cttgaacagg
     6361 gaaaaagttg actagaatca gttatagtct tttctaataa caggtcatag tcacttataa
     6421 gaattactaa taacatgttt tagtattcta attggaatat agctgtaaag taagaattac
     6481 aaaggatttg agacgtttgc ttcaagtctt tttcttttgt ccgaaacaga tatatagttt
     6541 caaactatat caaaccctaa ttttttacaa ttatacagac gctttctttt ctgttaagat
     6601 agtttcaaca acaaattttg gaggacacat catgtcaact acaatcatcg gtttccctcg
     6661 tttgggcgaa ttccgtgaat taaaatttac aactgaaaaa tactttagaa aagaaatctc
     6721 agaagaagaa cttttagcag cagcaaaaga cttgcgtgct aaacactgga acattgtcaa
     6781 agaaaaaggc atcactgaaa ttccatcaaa tgacttttct cactatgata acttcctaga
     6841 tgcggctttc cttttcaacg tggtgcctgc atccgttcaa aacttggact tgtctgacct
     6901 tgagcgctac ttcgctttgg gacgtggtta ccagggagaa aaaggggacg ttcgcgccct
     6961 tccaatgaag aaatggttca acactaacta ccactacatc gttcctaaat ttgaaaaaga
     7021 cactcaagta aaattggctg gtcacaagat tttcgatgag ttccaagaag ccaaagaact
     7081 tggattgaac actcgtcctg ttcttgtagg tcccttcact ttccttcaat tgtcagactt
     7141 tgaagaaggc gtgaaagcag acgacttcgt agatagctta gtggctgctt accaagaagt
     7201 ttttgctaaa ttggctgaac ttggtgcgac tcgcatccaa ttggatgaag cggctcttgt
     7261 aaaagacttg acagctgaag aaaaagctct cttcttgaac ctttacaaca aactcttggc
     7321 tgacaaaaaa ggtcttgaag tcttgcttca aacttatttc ggtgatgttc gtgacgtata
     7381 cgctgacctt gtaaacttac cagtagatgc tatcggtctt gactttgttg aaggtaagaa
     7441 aactcttgaa ctcgttaaag gtggcttccc agctgacaag actctctatg taggtattgt
     7501 caatggtaaa aacatctggc gcaacaacta cgaaaagagc ttggctgttc ttgagcaaat
     7561 tccagctgaa aacatcgttt tgacaagctc ttgctcactt cttcatgtgc catttacaac
     7621 tgctaatgaa gaatttgaac cagcactctt gaaccacttt gcctttgcag ttgaaaaatt
     7681 ggatgaaatc cgtgacttgg atgctatccg aaatggtcaa ggttcagaag ctcttgcagc
     7741 caacaaagaa ctctttgcga ctgagcgtgt tggtgaaaat gctgaacttc gtgcgcgtat
     7801 cgctggcttg acagacgcag actacactcg tttgccagcc tttgcagaac gtgaagctat
     7861 ccaagaagaa gctttcaaac ttccagctct tccaacaaca acgattggtt cattccctca
     7921 aacaaaagaa gttcgtgcca aacgtttggc ttaccgtaaa ggtgaattgt ctcaaaaaga
     7981 gtacgacgct ttccttgctg aaacgattga cgaatggatc aagtggcaag aagatattga
     8041 ctttgatgtc cttgttcacg gtgaatttga gcgtaatgac atggttgagt acttcggtca
     8101 aaacttgtca ggatacctct tctctaaaaa tggatgggta caatcatacg gtatgcgtgg
     8161 ggtaaaacca ccaatcatct ggggtgatgt cactcgtctt aaccctatca ctgttaaatg
     8221 gtctagctat gcacaaagtc gtacaaacaa acctgttaaa ggtatgttga ctggacctgt
     8281 taccatcctt aactggtcat tcccacgtga agacatctct atcaaggatt caactctcca
     8341 aatcgccctt gctatcaagg atgaagtact tgaccttgaa gctgctggtg tgaaaatcat
     8401 ccaaatcgac gaggctgctc ttcgtgaaaa attgccactc cgccgtagcg actggtacga
     8461 agactacctt gactgggcta ttcctgcctt ccgcttggta cactcaacag tagcgccaga
     8521 cacacaaatc cacactcaca tgtgttactc agaatttaca gatatcatcc cagctatcga
     8581 taacatggat gcagacgtta tttcctttga agctaaccgt tcaaaccttg aaatcttgga
     8641 cgaactcaaa gcgaaaaact tccaaacaga agtgggacct ggggtttacg atatccactc
     8701 acctcgtgta ccaaatgaag gcgaaatcga caacacaatc gaagccatcc ttgctaaagt
     8761 gccaagcaag aaagtttgga tcaaccctga ctgtggtttg aaaacacgtg gtatcccaga
     8821 aacaaaagaa agcttgatcc gccttgttga agcagctaaa gctgcgcgtg agaaattgta
     8881 agattggatt tctctccata cagtggttgt tcaaaaagaa atcaactaga aaaggttatt
     8941 acatatgtca cgccaaacac cgtcactctc atttgaagtg ttccctccaa acccagccgt
     9001 gggtaatgat aacattattt cagccttgca ggatatgcag gagttggctc cccattttat
     9061 cagtgtaact gccagcaata ataaatttaa tatcaaggaa acgacggttc gtttggctga
     9121 ctttatccaa aatgatttgg cgattccgac cattgcccac ttgccagcta tttatctaac
     9181 taaggacaag gttgctgaaa ctattgctga cttggacaaa gttggggtgc agaaaatctt
     9241 ggctcttcgt ggggatatta ttccagacgt ggaaccacaa aaggatttcc gctatgcaac
     9301 cgacttgatt gagtttatca aggaacaaac ccctcacttt gatattattg gagcttgcta
     9361 tccagaaggg catccagatt cgccaaatca gatttcagat attcaaaatc ttaagaagaa
     9421 agtggatgca ggctgttcga gcctcgtaac tcagctcttc tttgacaatg agcgcttcta
     9481 tgattttcag gacaagtgta tcttggctgg gattgatgtt cccattcatg caggaattat
     9541 gccaattctg aatcgaaatc aggctctccg actcttgaag acttgtgaga atatccatct
     9601 tccacgcaaa tttaaagcca tcttagacaa gtatgagcat gaccctgagt cgctcagagc
     9661 agcaggactt gcctatgcag tggaccaaat cgtggacttg gtaactcagg atgttgccgg
     9721 tgtgcatctc tatacgatga ataatgctga tacagcaaaa tacatccatc aagcaaccca
     9781 tgccttgttt aatcaccagt ctctaggata ataaaagcaa accattcttc tcaggtgagg
     9841 ggaatggttc ctttttaatg gtaaagacct cactttttaa gaaaaatatg ataaaataaa
     9901 ttctgtacgt acttgataca aagatgaagg tattaaataa tacaatgcat ttaaactgta
     9961 agatttaacg acacgagtga gtcaaatcga tgttatttga cgagagagtt agtaaagcat
    10021 ttagctaatc gcccgatagc gattagcgtg aaagctttag atactttagt attaaacctt
    10081 tctaatgatg tatcttgaaa actgaacttg cctacaactc tgtggaaaaa gataaatctc
    10141 cctaggagta gtcgctccgt cgttcgattt cctatcttcc tttgagttgc ttgacggctt
    10201 ggtatcttga tgacttgaat tttggtctca tttcttagga aaaaagataa gcttcctagc
    10261 actcgtcgag tgcgacgtca ccttcctatt tttctacaga aatgttcggc aagccgaacc
    10321 gtccaaaata tcttgtgtaa ttgaacacgg ccgaaaagct gtgtaaaaaa gataaactgt
    10381 cttgtcttca tcgaagactt cgtcagtttc ctatttttac tttgcttttg acgtccttgg
    10441 tatcttgatc tttgtaggca aggcgtataa tttcatcaat ccaaagggga ttaaaatggc
    10501 aaaacaagtg tttcaaacga cttttgcggg tcgtgagtta attgtagaga ctggtcaggt
    10561 tgctaagcaa gcaaatggat ctgttgtcgt acgttacggt gagtcaactg tcttgactgc
    10621 tgccgttatg tctaagaaaa tggcaactgg ggatttcttc ccactccaag tcaactacga
    10681 agaaaaaatg tatgcggctg ggaagtttcc tggtggcttt atgaaacgtg aaggacgtcc
    10741 ttcaacagat gcgaccttga cagcgcgttt gattgaccgt ccgattcgtc ctatgtttgc
    10801 ggaaggtttc cgtaatgaag tccaagtcat caatacagtg ctttcttatg atgaaaatgc
    10861 atctgcacca atggctgcta tgtttggttc atctttggca ctgtctattt cagatattcc
    10921 atttgacgga ccaattgctg gggtacaagt gggatatgta gatggccaaa tcatcatcaa
    10981 cccaagtcaa gaacaagcag agcaatctct tcttgaattg acagtagctg gaaccaagca
    11041 cgctatcaac atggtagagt ctggtgccaa agaattgtca gaagaaatca tgttggaagc
    11101 gcttcttaaa gggcacgaag ctgtcaaaga attgattgcc ttccaagaag aaatcgttgc
    11161 tgctgtcggt aaagaaaaag cagaagtgga attgcttcac gtggatgctg aattgcaagc
    11221 tgaaatcatt gcagcctaca acagtgacct ccaaaaggca gttcaagtag aagagaaatt
    11281 ggcacgtgaa gctgcgactc aagtagtgaa agaccaagtg actgccgttt acgaagaaaa
    11341 atatgcggac cacgaagaat ttgaccgtat tatgcgtgat gtggctgaaa ttttggaaca
    11401 aatggaacac gcagaagtgc gacgtttaat tacagaagac aaggtgcgtc ctgatggtcg
    11461 taaggtcgat gaaatccgtc ctttggatgc ggttgttgac ttccttcctc gtgtacatgg
    11521 ttcaggtctc tttactcgtg ggcaaactca agctctttca gtcttgacct tggctccgat
    11581 gggagaaact caaatcattg atggtttgga tccagagtac aagaaacgct ttatgcacca
    11641 ctataacttc cctcaatatt ctgtagggga aacaggtcgt tacggtgcgc caggtcgtcg
    11701 tgaaatcggt cacggtgctc ttggtgagcg tgctcttgct caagtcttgc caagcttgga
    11761 agaattccca tacgctatcc gtctagtagc agaagttttg gaatcaaacg gttcttcatc
    11821 tcaagcttct atctgtgcgg gaactcttgc ccttatggct ggtggtgtgc caatcaaggc
    11881 gccagtagct ggtattgcta tgggacttat ctcagatgga aataactaca cagtattgac
    11941 agatatccaa ggtttggaag atcactttgg agatatggac ttcaaggttg caggtactcg
    12001 tgatgggatt acagcccttc aaatggatat caagattcaa gggattactg cagaaatctt
    12061 gacggaggct cttgctcaag ccaagaaagc gcgttttgaa atccttgatg tcattgaagc
    12121 aaccattcca gaagttcgtc cagaattggc tccaactgct ccgaaaattg atacgatcaa
    12181 gattgatgtg gacaagatta agattgtcat cggtaagggt ggagaaacca tcgacaagat
    12241 tatcgctgaa acaggtgtta agattgatat agacgaagaa ggaaatgtgt ctatctactc
    12301 tagtgaccaa gatgctatta accgtgccaa agaaattatt gctggtttgg ttcgtgaagc
    12361 caaagtggat gaagtttacc gtgctaaagt cgttcgtatc gagaaatttg gtgcctttgt
    12421 taacctcttt gataagacag atgcccttgt tcatatctct gagatggctt ggactcgtac
    12481 caatcgtgta gaggatttgg tagaaatcgg ggatgaagtt gatgttaagg ttatcaaaat
    12541 tgatgaaaaa ggccgtatcg atgcctctat gaaggctctt ctacctcgtc cgccaaaacc
    12601 tgagcatgat gaaaaaggtg aaaagtctga gcgccctcac cgcccacgtc atcacaagga
    12661 tcacaaacct aagaaagaat ttacagaaac accaaaagat tcagagtaag aaaaggagaa
    12721 atgtatgggg tggtggcgcg aaaccattga tatcgtaaaa gaaaatgatc cagcggcccg
    12781 caccactttg gaggttttgc tgacttatcc aggtgtcaag gccttggcgg cccaccgtct
    12841 ctcgcatttt ctctggaagc acggcttcaa actcttagct cgtatgcaca gtcagttttg
    12901 gcgcttttgg actcagattg agattcatcc aggagcccag attgattcag gtgtctttat
    12961 tgaccatggt tctggtctgg tgattggaga gacagcgatt gttgaaaaag gcgttcttct
    13021 ctatcacgga gtgactcttg ggggaacagg gaaagactgt ggcaaacgcc atccgactgt
    13081 acgaaaggga gccctcatat cagcccatgc ccaagttatc gggcctgtgg aaattggtga
    13141 aaatgccaag gtcggtgctg cagcagttgt cgtagcagat gtacctagtg atgtgacggt
    13201 tgtcggtatt ccggccaaga ttgtccgtct tcatggtaag aaagatgagc ctgtcattca
    13261 cgaagtcgaa gaaaaacgag agtattatgt caataaactc gagcaggcta aagatgccag
    13321 tcacagatcg tctggtttgt agaggatacc tatatgattc aagcaagaaa caagttaagc
    13381 caagaggagc tatctgaggc gaaaaaagta attaactgtt gccaaaacta tgacggtacc
    13441 tatcgcgatc cctatctctc taacatgctt aattttgacc caaacatgcc cgcctttttc
    13501 ctttattatg aaaaaggcga acttgttggt ttattaactg tctatgcaga tgaccaagat
    13561 gtagaagtaa cgatactggt tcatccaggt catcgccgtc aggggattgc gcgtgcattg
    13621 tttactagtt ttgagagaga aacagcttct ttccccattc ggtcagtcac ttttcagaca
    13681 gaacgtattt ttttagagaa tcatcctgac tttgccagta actggggact aatcgaggat
    13741 gaagagacag aaacttggtt aggtaaggat agaagacctt atccgttagc aaatgtttcc
    13801 catcttgaag ttttgttagc agatagttcg tatcaggatc aaattagtca attaaaattt
    13861 caggcatttt cagaggaaca tgaatcgaga gaagttgtgg atagatatgt cgctgaagct
    13921 ctgaaggatc cagaaagtcg cttatatatt ttgttaaaag acggtcaggt tattgggact
    13981 tgcacggtag atttatcgac taatacgaat tacttctacg gtttagcaat atcggaacct
    14041 gaacgtggga aaggctatgg aagctactta gcaaaatccc tcgtcaacca actaattgag
    14101 caaaatgaca aggaatttca gattgcagtg gaagatagca atgtaggtgc caaacgtttg
    14161 tatgaaaaaa ttggctttgt caaacagact caggtggttt atttgaatga gaaaggagta
    14221 agggattccg aagtgtagag acattcggac tgaaatttac ttgagctctt agtttagtga
    14281 tgcaactaac agttcttgga ttttagcttt cctgattatg atttatgatt aaaatctatg
    14341 acaccatgtc tcgtgatttg cgagaatttg tcccaattga gaacggtaag gttaagatgt
    14401 atgtctgtgg gccaaccgtg tacaactata ttcatgtagg gaatgctcgt tcgacggtag
    14461 cttttgatac gattcgtcgc tattttgagt accgtgggta taaggttgcc tatatttcca
    14521 attttacaga tgtggatgat aagattatca accgtgccag ggaagaaggt atcacgcctc
    14581 aggaggttgc ggataagtac atcgctgcct ttcgtgagga tgtgacggcc ttaggcgtga
    14641 aacctgcgac tcgccatccg cgtgtagtgg agtttatggc agacatcatc cgttttgtgg
    14701 aagacttgat cgagaaaggc tttgcctatg agagtcaagg ggatgtctat ttccgtgtag
    14761 aaaaatccca caactatgct aaattggcta ataaaacttt ggaagatttg gatctaggtg
    14821 cttcaggtcg taccgatgaa gaaacggctc gtaaggaaaa tcctgtagat tttgctctat
    14881 ggaaatcttc caaaccaggt gagatttctt gggatagtcc ttggggacct ggacgtccgg
    14941 gttggcatat tgagtgttca gtcatgtcga cagagatttt aggtgatacc attgatatcc
    15001 acggtggtgg agctgaccta gagtttccac accacaccaa tgaaattgcc cagtctgaag
    15061 ctaaaacagg caaggctttt gctaactact ggatgcacaa tggctttgtc aatatcgaca
    15121 atgtcaaaat gtctaagtcc ttgggtaact tcattacggt acacgatgcc cttaaaactc
    15181 ttgatgggca agtacttcgt ttcttctttg cgacccagca ctaccgtaag cctatcaact
    15241 tcacggaaaa ggcagttcgc gatgccgaga ccaatctcaa gtatctgaag aatacttacg
    15301 aacaaccatt tacaggaaat gtggatgccc aagagttaca aaactttaaa gataagtttg
    15361 tagcagctat ggatgaagat tttaatgctg ccaacggtat cacagttgtc tttgaaatgg
    15421 ccaaatggat caactcaggg aactatgatg caagtgtcaa gcaagctctt gcagatatgt
    15481 tagaaatttt tggaattgtc tttgttgagg aagttttgga tgcagagatt gaagacttga
    15541 ttcaaaaacg ccaagaggcg cgtgccaatc gtgactttgc gacagcagac caaatccgtg
    15601 accaattggt tactcaagga attaagctcc ttgataccaa ggatggagtg aggtggacac
    15661 gtgattgatg tcaatctcat taacgggatt gcgctagcct ttgaggggga tgcggtgtat
    15721 tctatgtata ttcgccgtca cctcatcctc aaaggtatga ccaaacccaa taaactccat
    15781 caagaagcaa ctaagtacgt gtcagccaag gctcaggctc gcctgattgc tctcatgttg
    15841 gaggagcagg tcctaacgga aaaagaagaa gaaatctaca aacgtggccg caataccaat
    15901 agccacacaa aggctaaaaa tgcagatgtc gtgacttatc gtatgtccac gggatttgaa
    15961 gcggttatgg gctatctcca tatgactgag aatctggaac gtcttgagag tttggtttca
    16021 tggtgcatcc aaaaagtgga gggctagaac atgagggcaa aagaactaca agactggttt
    16081 cctgaggctc ggatttcaga ccaaccagta gagaaagagg gctatctcac gctcccttta
    16141 gcttctcagc agtggatttt gctggaggaa gctgggctca gcgagcgtga aaagcagttg
    16201 gttgcccttt tgacccagca ggagcaggct cgttcgctaa acccttggta ttcctatctg
    16261 gttgagggca agggacaggc accgcaagtt tttaaaaaga ttcagttggt ttattgccat
    16321 ctttcttatt ttcagcagga aaatctggct tcttggctag atatgatgcg gactcttttt
    16381 ccgaattgtc agacagtgct acaggtcgga gctcaggatt atgttttcgt gcttcaacaa
    16441 gacaaataca cttctgtaag agatatttta agtgatacga ttgaagcggt tgagtatgac
    16501 tttggacttc gtctttctat catgttgggt caggtttggt ctcagacggg acatcaagcc
    16561 ctatcagact taatcaaagc tgagcgggat ttgttcaaga catggtggcg tcagggtcac
    16621 caaggtgttc atactttttc tcagctctat ctttggagta tgggagaaag actcgtggac
    16681 ttgaagccaa tcaaggaatg tctacaccag atgattttgg atcaagatca gattcaggaa
    16741 atcattctct ctctttggga aaatagtgct gttctcacta aaacagccca gcaactctat
    16801 ctgcaccgca attctctcca atacaagatt gataaatggg aagagttgac agggcttcag
    16861 ttgaaagagt tgaccgacct gaccttgtgt tatcaattga ttttaggttc tttgtcaact
    16921 atagttggtt tgtaaagaag ttaatatggc tctttgtcaa ctgtagtggg ttgaaaaaaa
    16981 gctaagctcg agaaaggaca aattttgtcc tttctttttt gatattcaga gcgataaaaa
    17041 tccgtttttt gaagttttca aagtttcgaa aaccaaaggc attgcgtttg ataagtttga
    17101 tgagattatt ggtcgcttcc aatttggcgt ttgaataggg tagttgaagg gcgttgacga
    17161 ttttctcttt gttctttaga aaggttttaa agacagtctg aaaaatagga tgaacctgct
    17221 tcagattgtc ctcaatgagt ccgaaaaatt tctcagggtc tttgttctga aagtgaaaaa
    17281 gtaagagttg atagatctga tagtggtgtt tcaagtcttc tgaatagctt aaaatcttgt
    17341 caagaatttc tttatttgtt aagtgcatgc gaaaagtagg gcgataaaaa cgtttatcgc
    17401 tgagtttacg actatcctgt tggatgagtt tccagtaacg
//
LOCUS       DAVLUM010000045        16830 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLUM010000045 DAVLUM010000000
VERSION     DAVLUM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.045"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            756..1079
                     /locus_tag="VYN42_001385"
     CDS             756..1079
                     /locus_tag="VYN42_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1462448.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            1137..3080
                     /gene="thrS"
                     /locus_tag="VYN42_001386"
     CDS             1137..3080
                     /gene="thrS"
                     /locus_tag="VYN42_001386"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1462449.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(3129..4103)
                     /locus_tag="VYN42_001387"
     CDS             complement(3129..4103)
                     /locus_tag="VYN42_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1462450.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(4096..4773)
                     /locus_tag="VYN42_001388"
     CDS             complement(4096..4773)
                     /locus_tag="VYN42_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462451.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            4929..6002
                     /locus_tag="VYN42_001389"
     CDS             4929..6002
                     /locus_tag="VYN42_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1462452.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(6093..6395)
                     /locus_tag="VYN42_001390"
     CDS             complement(6093..6395)
                     /locus_tag="VYN42_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462453.1"
                     /translation="MYLVIGIVLAFIVSFWKYNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(6464..6901)
                     /locus_tag="VYN42_001391"
     CDS             complement(6464..6901)
                     /locus_tag="VYN42_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1462454.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(6977..7819)
                     /locus_tag="VYN42_001392"
     CDS             complement(6977..7819)
                     /locus_tag="VYN42_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1462455.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            7931..8581
                     /locus_tag="VYN42_001393"
     CDS             7931..8581
                     /locus_tag="VYN42_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1462456.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            8760..9437
                     /locus_tag="VYN42_001394"
     CDS             8760..9437
                     /locus_tag="VYN42_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV1462457.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIITFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSTKEY"
     gene            9539..9940
                     /locus_tag="VYN42_001395"
     CDS             9539..9940
                     /locus_tag="VYN42_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462458.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISL"
     gene            9971..10385
                     /locus_tag="VYN42_001396"
                     /pseudo
     CDS             9971..10385
                     /locus_tag="VYN42_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10424..10867)
                     /locus_tag="VYN42_001397"
     CDS             complement(10424..10867)
                     /locus_tag="VYN42_001397"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1462459.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(10897..13119)
                     /locus_tag="VYN42_001398"
     CDS             complement(10897..13119)
                     /locus_tag="VYN42_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1462460.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            14078..14707
                     /locus_tag="VYN42_001399"
     CDS             14078..14707
                     /locus_tag="VYN42_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1462461.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKYLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFHFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGSATTIAHEKAFNPFF"
     gene            complement(14830..16722)
                     /gene="pepO"
                     /locus_tag="VYN42_001400"
     CDS             complement(14830..16722)
                     /gene="pepO"
                     /locus_tag="VYN42_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1462462.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEESWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         4877 a         3880 c         3160 g         4913 t
ORIGIN      
        1 caagaaaact aaccatgatt ctagtgaaaa gaaaaatctt ctttgtcaac aaatttactt
       61 tcttgtttta aacatgctat aataatcata gcaagagatc taagttgtct gtttttttaa
      121 aacgaggtga ttatcatgcg tagattctat tcccatctcc cctactatct ggtcatatta
      181 ttcttttatt ggccacttta tgagttgttc ttgctagttg tttctgaccc ccttacacta
      241 tataaacaat cttctcttct ttacacctct ggtaatcttg attgtatcgt tactctatag
      301 ctaccgtttc cgtttctcac tttgatggtt agttggtaac ggactgctct tttactttac
      361 tatcataacc tttggtgagt ttatactaat ttacttgcta atctatgaaa cagttgctct
      421 ggtgggcatg gattctggta ttagcatcaa gcatattcta caaaatatga aaaacaaaaa
      481 actttcacaa aatccttgaa aaatctcaca atcatgctat aataatccat agagacaagt
      541 cacttagtcc ctttctacta gagagtgcgt ggttgctgga aacgcatagg aagtctaaac
      601 tgatactact cttgagtttt ttatgaaaac ataaaacggt ggccacgtta gagccaatca
      661 gaggtgtccc tctcttttga ggtacataaa tgaaggtgga accacgttgc gacgtccttt
      721 cgaggatgtc gcattttttt attaggatac taattatgga gttgcaagaa ttagtggagc
      781 gcagttgggc aatccgacaa gcttatcacg aactggaagt taagcatcat gatttcaagt
      841 ggacggtaga agaagacctc ttggctttat ctaatgatat tggaaatttc caacgactgg
      901 tgatgacaaa gcaaggacgc tactatgatg aaacacccta cacactggaa caaaaacttt
      961 cagaaaatat ctggtggcta ttagaacttt ctcaacgttt ggatatagac attctgacgg
     1021 aaatggaaaa cttcctctct gataaagaaa agcaattgaa cgttaggact tggaagtagt
     1081 ctgctgataa aaaatcaatg cttagaaact atgaaataat aaaaaaggag aacatcatga
     1141 ttaacattac tttcccagat ggcgctgttc gtgaattcga atctggcgta acaacttttg
     1201 aaattgccca atctatcagc aattccctag ctaaaaaagc cttggctggt aaattcaacg
     1261 gcaaactcat cgacactact cgcgctatca ctgaagatgg aagcatcgaa attgtgacac
     1321 ctgatcacga agatgccctt ccaatcttgc gtcactcagc agctcacttg ttcgcccaag
     1381 cagctcgtcg tcttttccca gacattcact tgggagttgg tccagccatc gaagatggtt
     1441 tctactacga tactgacaac acagctggtc aaatctctaa cgaagacctt cctcgtatcg
     1501 aagaagaaat gcaaaaaatc gtcaaagaaa acttcccatc tattcgtgaa gaagtgacta
     1561 aagacgaggc acgtgaaatc ttcaaaaatg acccttacaa gttggaattg attgaagaac
     1621 actcagaaga cgaaggcggt ttgactatct atcgtcaggg tgaatatgta gacctctgcc
     1681 gtggacctca cgttccatca acaggtcgta tccaaatctt ccaccttctc catgtagctg
     1741 gtgcgtactg gcgtggaaac agcgacaacg ctatgatgca acgtatctac ggtacagctt
     1801 ggtttgacaa gaaagacttg aaaaactacc ttcaaatgcg tgaagaagct aaggaacgtg
     1861 accaccgtaa acttggtaaa gagcttgacc tctttatgat ttcacaagaa gtgggacaag
     1921 gtttgccatt ctggttgcca aatggtgcga ctatccgtcg tgaattggaa cgctacatcg
     1981 taaacaaaga gttggcttct ggctaccaac acgtctacac tccaccactt gcttctgttg
     2041 agctttacaa gacttctggt cactgggatc attaccaaga agacatgttc ccaaccatgg
     2101 acatgggtga cggggaagaa tttgtccttc gtccaatgaa ctgtccgcac cacatccaag
     2161 ttttcaaaca ccatgttcac tcttaccgtg aattgccaat ccgtatcgct gaaatcggta
     2221 tgatgcaccg ttacgaaaaa tctggtgccc tcactggcct tcaacgtgta cgtgaaatgt
     2281 cactcaacga cggtcaccta ttcgttactc cagaacaaat ccaagaagaa ttccaacgtg
     2341 cccttcagtt gattatcgat gtttatgaag acttcaactt gactgactac cgcttccgcc
     2401 tctctcttcg tgaccctcaa gatactcata agtactttga taacgatgag atgtgggaaa
     2461 atgcccaaac catgcttcgt gcagctcttg atgaaatggg cgtggactac tttgaagccg
     2521 aaggtgaagc agccttctac ggaccaaaat tggatatcca gattaaaact gcccttggaa
     2581 aagaagaaac cctttctact atccaacttg atttcttgtt gccagaacgc ttcgacctca
     2641 aatacatcgg agctgatggc gaagatcacc gtccagtcat gatccaccgt ggggttatct
     2701 caactatgga acgcttcaca gctatcttga ttgagaacta caagggggcc ttcccaacat
     2761 ggctggcacc acaccaagta accctcatcc cagtatctaa cgaaaaacac gtggactacg
     2821 cttgggaagt ggccaagaaa ctccgtgacc gcggtgtccg tgcagacgta gatgagcgca
     2881 atgaaaaaat gcagttcaag atccgtgctt cacaaaccag caagattcct taccaattaa
     2941 ttgttggaga caaagaaatg gaagacgaaa cagtcaacgt tcgtcgctac ggccaaaaag
     3001 aaacacaaac tgtctcagtt gataattttg ttcaagctat cctagctgat atcgccaaca
     3061 aatcacgcgt tgagaaataa gagtctagca taaaagcctc caatctggag gctttttctc
     3121 atctattttt actcaaggac taagttcact tgagcaaact gaatccgcac tgtcgttcct
     3181 tttccgacct cagactcgat acgaatctgg tgccccagtt cttcagaaat tttcttagat
     3241 agataaaggc caagtccaga ggactgctgg gtcaaacggc cattgtatcc tgaaaagcca
     3301 cgttcaaata ctcggaggac atcactgttt tttatcccga ttcccgtatc tttgatacaa
     3361 agctcttggt catccatata aatctccaga ccaccttcct tggtgtactt gagactgttt
     3421 gagatgattt gctcaataac cactagcagc cactttttat ccgtcacgat ttctttatca
     3481 aggtcatgta gattgacatt taagcctttt tgaataaaga aaagagcata tttacgaatt
     3541 atttccttga ccaagtcctc aatttgaacc tgctttaaga gcaaatcatc atggaaactt
     3601 tctaaacgca ggtactgtaa aactaggttg gtataggagt cgattttgaa aatttcctgt
     3661 tctagctgct gcttcagttg gcggtcgacc acttctgcaa ctaagagttg actggctgca
     3721 atgggggtct ttatctgatg gacccacaag gtatagtaat ccagcaaatc cgtcagtttt
     3781 ctttctgctt ttgacctctg ctgatagagt tccatctcac gcgcttctaa tttttctgct
     3841 aaagctattt ccaaaggaga cttggcttcc ctctctccat agagaagttc ctggcgatag
     3901 acctgcgttt ccaccaatat gtcccaagtg aaaaataata tggttacaaa gcaacacaag
     3961 aagaaaaagt agaggaagta aattcctaga ctggcaaata aaaactgaaa gagtaagaca
     4021 agaaatgcca aagaaagcag atagataaaa agacgactac gggagcgcag ataggctaga
     4081 aaaaattgtt tccaatcaag catgcttcaa tccgtaccct attcctttct tggtctcgat
     4141 aaatcctacc aatccctgct cctccaactt tttacgcaaa cgagccacat tgacagagag
     4201 ggtattatca tcaatgaaaa agtcactgtt ccaaagttcc cgcatcaggt cgtcacgtgc
     4261 tacgatgttg cctgcatgct caaataacac gcgtaaaatc tggaattcat tcttggtcaa
     4321 attcaagact tgcccttgat aatgtaaatc catggatttg gtattgagga taacaccagc
     4381 atattccagc aaactctcat cacgcccaaa ctcataggaa cgacgcaaca agccctgaac
     4441 cttagctaaa agaacctgct ggtcaaaagg cttggtcaca aagtcatccg cccccatatt
     4501 gattgccatg acaatatcca tagcctggtc tctcgaagaa agaaacatga taggtacctt
     4561 ggaaatcttg cggatttcct gacaccagtg ataaccatta aacaagggca aaccaatatc
     4621 catgaggacc agatgaggtt ccgactgaac aaatagactc aaaacttcca taaagtcttc
     4681 taccaggacc acttcaaatc cccattcaga gagcattttc ccaatctgtt gacgaatgac
     4741 ctgatcatct tctattaata aaatcttgtg catgcgcttc tccttttcca ttattataac
     4801 agatttttcc atgctagatg gtctgaaact gaatttgaaa tagcctgttt ttagccagta
     4861 caaacaggct atgctactag ctaatttgag ggaaatttgc taagataaat aaaaagaaag
     4921 gagctcttat ggccaatatt tttgactatc tgaaagatgt cgcatatgat tcttattacg
     4981 accttccctt gaatgagtta gacattctaa ccttaataga aatcacctac ctctcctttg
     5041 ataatctggt ctccacactt cctcaacgtc ttttagatct agcacctcag gttccaagag
     5101 agcccaccat gcttactagc aaaaatcgcc ttcaattatt agatgaattg gctcaacaca
     5161 agcgcttcaa aaattgcaaa ctctcccatt ttatcaacga catcgaccct gaactgcaaa
     5221 agcaatttgc ggctatgact tatcgtgtca gcctcgatac ctatctgatt gtatttcgtg
     5281 ggacagatga cagtatcatt ggctggaagg aagatttcca cctgacctat atgaaggaaa
     5341 ttcctgctca aaagcacgcc cttcgctatt taaagaactt ttttgcccat catcctaagc
     5401 aaaaggttat tctggctggg cattccaagg gaggaaatct cgctatctat gctgctagcc
     5461 aaattgagca aagtttgcaa aatcagatca cagcagttta tacatttgat gcacctggtc
     5521 tccatcaaga attgacacag actgcgggtt atcaaaggat aatggataga agcaagatat
     5581 tcattccaca aggttccatt atcggtatga tgctggaaat tcctgctcac caaatcatcg
     5641 ttcagagtac tgccctgggt ggcatcgccc agcacgatac ctttagttgg cagattgagg
     5701 acaagcactt cgttcaactg gataagacca acagtgatag ccggcaagta gacacaacct
     5761 ttaaagaatg ggtggccaca gtccctgacg aagaacttca gctctacttc gacctcttct
     5821 ttggcactat tcttgatgct ggtattagct ctatcaatga cttggcttcc ttaaaggcgc
     5881 ttgaatacat tcatcatctc tttgtccaag ctcaatccct cactccagaa gaaagagaaa
     5941 ccttgggtcg ccttacccag ttattgattg atactcgtta ccaggcatgg aaaaatagat
     6001 aatactcttg aaaattaaat gtatacaaaa caaaagacct agaatacata ctttcatgtg
     6061 cattataagt ctttttaaat agaatctaat agtcaataaa aatcaaagag cattgagaga
     6121 taatggggct tggaacgtcc ctctcgcttc aacaaaatga ccccattata gattaaaaag
     6181 atgccactta gaaaaagcaa aaaaggaagt aatacaaagg caaatacata aaaagctaac
     6241 tgaacattct cgtatccatt tttataaaaa aggtaggata gataaaaata acttgaaatg
     6301 agggataata aaaataatac tggattccac aaacttctat tatacttcca aaatgacact
     6361 ataaaggcta atacaattcc tataacgaga tacatttctt actcctttaa tagctacatt
     6421 ttatcataat tatccaaaga aaaaaagagg gcatttatcc ctcttaatcc ttcatctgac
     6481 tctctgcatc ggccacgact ttttctagac tggtctgacc aagttctgcc tccatagtca
     6541 actgaattct ctccaatttt tgatccaaaa catcatgaat atgagctcct acagggcaat
     6601 ttggattcgg attgtcatgg aaactgaaga gttgacctgt cttaccaaga cattcgaccg
     6661 cctgataaac atctaaaaga ctaatatcct taaggtcctt gacaatctct gttccgcccg
     6721 ttccacgcgc tactgaaatc agctctgcct tcttcaactg ggacaagatc tttctgataa
     6781 tgacaggatt gaccccgaca ctagcagcca gaaaatcact ggtcaccttg ctttccttcc
     6841 cctcgagggc aatgattatc agcatatgag ttgcaatggt aaatctactt ggaatttgca
     6901 tcctcttctc ctttttacga ggctaccctg cctctactct tctttttcta ttattatacc
     6961 ctttttagtt gtaatgtcaa tcgttaccac ttttcaacca gtcgtctaac tcccgatcgc
     7021 aaccctcttt ctgagccaat tctctcaaaa attcctgatg atgagtatgg tggatcccat
     7081 tgaccagact ttcatagtaa acctcaaaat agggaagtct caggtcttta gccagctgca
     7141 attcagctgc cacatcgtaa tctacccgtc ggaagtccat atctaccagg cctttgtcat
     7201 caaactccaa aatcatatac tgggcccgca agtccttccg tagctgagcg tccaaaaaga
     7261 aaggttggcc aatcgaaccc ggattgacaa tcaattgccc accagtcccg taacgaagca
     7321 actgctggtg aatatgtcca taaacagcaa tatcacaggg aggatgagtc accaagcggt
     7381 caaactcctc ttgtttgcca gtatgaatca actctcgccc ccagttctta tcaggcagat
     7441 gatggctaat tcccaccgtc aaatccccaa actgacgatg aatttgaaga ggttgattgt
     7501 ggagcacttc aatttcttct agggaaattt cctctaaaac atactggcac tggcgcaaga
     7561 gatagcgttg actagggcga gtactatcca attccttacg gacaccatgc caaagactgt
     7621 cttcccagtt tcccaaaact ctagccgtaa tcggtagttg atccaacaag tccaaaatcc
     7681 ttctacgtcc tgtccctggc atgagaatat ctcccaaaag ccagtattca tccactccta
     7741 gctgctgagc atctgccaaa acagcctcca aggcggtggt atttccatga atatctgaaa
     7801 gaagagctat tttcgtcata tccatctcct cgttttttct cttgcaataa gtataacata
     7861 aaaagtcaca gctagagaaa tctagctttt tttgatatac tagataaaga tattagacaa
     7921 gaggaaacga atgaccccaa acaaagaaga ctatctaaaa tgtatttatg aaattggcat
     7981 agacctgcat aagattacca acaaggaaat tgcggctcgc atgcaagtct ctccccctgc
     8041 cgtaactgaa atgatcaaac gaatgaaaag tgaaaatctc atcctaaagg acaaggaatg
     8101 tggctatcta ctgactgacc tcggtctcaa actggtctct gagctctatc gtaagcaccg
     8161 cttgattgaa gtttttctag ttcatcattt agactataca agtgaccaga ttcacgagga
     8221 agctgaggtc ttggaacata ctgtctctga cctgttcgtg gaaagactag ataaactgct
     8281 aggtttccct aaaacctgcc cccacggagg aactattcct gccaagggag aactcctcgt
     8341 tgaaatcaat aacctcccac tagctgatat caaggaagct ggcgcctacc gcttgactcg
     8401 ggtgcacgat agttttgaca ttctccatta tctggacaag cactcacttc acatcggtga
     8461 ccagctccaa gtcaagcagt ttgatggctt cagcaatacc ttcactatcc tcagtaacga
     8521 cgaggattta caagtgaata tggacattgc aaaacaactc tatgtcgaga aaatcaacta
     8581 atttctcaag tcccctacca accctgaaag ttttattttc agggttttat ttctatcatt
     8641 tgattttact ttcatttggt ggtagagtat ttgaaaaaaa aagaaaggta gtttaaccta
     8701 tgaaaaaatc actaaaaatt tttgctacat ctaaatagtt tgacctcttc ggggttgctt
     8761 tggtcgttgg gattgcgatt gcatctggtt acctcaactc acgcctcgat aaatttgtag
     8821 actggggatc atggacagct cttgtaccct ttggattgat ttccgtaacc aacgttggga
     8881 tttccatgtt gtccactcgt ttcacgggga aattaagcaa atggggaaat tactttggta
     8941 ttgttaatac cattttgtcc ggtgctattg attatatcct tggaaataag gcggccatca
     9001 ttacctatcc cgtcaccttc ctcatttata cctttgctat aaagaagtgg gaagcttcgc
     9061 aagaaggcag acccaaccaa atgagccaaa aacaggtaaa attggcggcc atcatcattt
     9121 ccatcatcac cttcctcttt gcctttgtga ccaactatat cggatatgag ggcaagatga
     9181 atctccttgc ctacgtaaca actattgcct ttgcactgtc cctcattgcc aatgctttga
     9241 atgcattgaa actaacaact cagtggggct tttggttgat ttacaatttc gttcagctga
     9301 caaaagctgg tattcaagga aacttcgcca atatcggtaa atacatcttt tatatcctca
     9361 atgcaatcgg agctttattt gtctggaatg atgaagaagt tagatacata gaaggaaact
     9421 caactaaaga atactagcca acttaagaga atctcccttc tgttattttt atcattttag
     9481 ttgtaactcc cattcttttg gagtagaatg aagttagata aaagaggaag gtcttgtcat
     9541 gaaaaaactc tatagaatcc attttatagc aattgcagtt attgatttgc tactatttgc
     9601 attttttatc attagactcg agacatcttt tgagtggctc ttgctctctg gtttaatttt
     9661 cttccttgct caaggactcc tgctatttct cttgatcgtc cgactcaaac atcaattcgc
     9721 tgagatttat cctcaaatca ataaaaagat tcgcttctac tatttagggg ttctcaccat
     9781 tgattttcta ttttttgttc tcttagcctt cattagttct cagcgttttt catctcttat
     9841 gtcaattatc actgcttgcc attctacttt ttactatatg acagctgact acctaagaga
     9901 aaactatcca gacttttacg acaaacacat ctctttatga gagtgtctct aaggaaaagg
     9961 aggttttagc atgaaaaaaa tcatcttcat caaaaccatt caactccttg tcattgatgg
    10021 aatcatgctg gcatttttga catttaaaag gggggcttac ttgggactgg attttgattt
    10081 atagtggttg gctcattttc tttcatcctg tgctattgac ctatctttca aaccaacttt
    10141 gtgaccactt tagtcaactc tattcccaga ttagaccgag attctggcgt tttgctttac
    10201 aaattctcct atgggatagc ctgatgattc tctccttggt gtctttaagt gatattccac
    10261 ttttccttca gggaactctc ctcatcctag gacatctcat cccttcctat cgcatctgcc
    10321 aaagcctgaa aagagacttc ccccaagcat atcaagaacc gatttctttt tggagtattt
    10381 tatgatcgat gagaaagacc aagccgactg ggcttggtct ttcttatctc tttttagtat
    10441 ctaggataat ggtaacaggt ccgttattaa ccagctcaac ctgcatatct gctccaaaga
    10501 tacctgtctg aacgggcact tcttgcgcta atttttgatt gaaagcatca tagaagtctg
    10561 atgccatatc aggtttagct gcccctgtaa aggctggacg attgcctttc ttagtatccg
    10621 caaagagggt aaactgagaa atagagagga tttctccttc aatatctttg acagacaggt
    10681 tcatcttgcc ttctgcgtct gaaaaaatcc gcatattgac cagttttctc acagcatagt
    10741 ccaaatcttc ctcttggtcc tctggtccaa caccaaccag caataaaagt ccctgattga
    10801 tttttccctg aatctggcct tctatactca cttgggcttt tttaacccgt tggataatga
    10861 ttttcataat agcctttcta gttagagcta ggacaactag ccgttggtcc gtttgacaga
    10921 gtaaacttct ggcacactct taattttatc gacaaccgtg gtcagtgtag agaggttggc
    10981 aataccgaag gacacatgga tattagcaaa cttcatatcc ttggttggtt gggcattgac
    11041 cgttgaaata ttcttggttg tatttgaaag aacttgcagt acatcgttca acagtcctgt
    11101 acggttgaga ccgtagatat cgatatgggc catatactcc ttatttgagc tagagtactg
    11161 gtcttcccat tccacatcaa ggagacgttg ctcgtagttt tcttgggcac gcaggttcat
    11221 acagtccaca cggtgaatag ccacaccacg acccttggta atgtagccaa caatatcgtc
    11281 accaggcacg gggttacaac acttagcaat ccgcactagg agaccagaag caccttcaat
    11341 aaccactccc ccctcatgct tgaccttgag agtttcttta ttttcaacct tgacctcgcc
    11401 acctttgaca agctcctctg cctcagcctt ggccttggca cgctcttcct cacggcgttc
    11461 cttttcagtc agacggttaa agacggtaat cgcaccgatt tccccaaaac caatggccgc
    11521 aaagagggag tcttctgtct tgtaactggt cttttgcaga acttgatcca tgtggcgctt
    11581 gtccataaat ttatttgcca catagccatt ttcttggaac tgagccatca gcatctcacg
    11641 acccttgttg acagacaatt ccttatcttg gtttttaaag aactggcgaa tcttattgcg
    11701 cgccttgcta gtcttgacca tattgagcca gtcacggcta ggtccaaagg agttcgggtt
    11761 ggcgataatt tcaacctgat cccctgtctt taacttggtt gtcagtggaa ccatgcggcc
    11821 attgaccttg gcaccagttg ctttttcacc gaccttggta tggatttcgt aggcaaaatc
    11881 aatcggtcct gaatctttgg gaagggaacg gacagctcca tctggggtaa aaacgtaaat
    11941 ctcctcagcc aaatagtttt ccttaacaga gtccacaaat tccttagcat catcagcctg
    12001 gtcttggagc tccatcatct ccttgatcca gttcattcca atagctgatt ccttgctgtt
    12061 aacttgcccc tttatacctt tcttataagc ccagtgagcc gcaaccccgt actcagccac
    12121 ctcgtgcatt tccttggttc gaatctggaa ttcaatcggc ccttttggtc cataaacagt
    12181 cgtatggata gactgataac cattggcctt gcggttggca atatagtctt tgaagcgacc
    12241 tggcatcggc ttccaaaatt catgcacgta accaagcatg gcataaacat cactttgggt
    12301 atctaaaata caacgaatag caatcagatc atagatttcc tcaaaccgtt ttctcttgtc
    12361 ctgcattttg cggaaaattg agtaaatatg cttgggacga ccataaatct tccctttcaa
    12421 gtgacgttct gtcgtatact cctctaattt tgtgactacc tcatccacca aggcctcacg
    12481 ctccctacgc ttttccttca tcatatgggt aatcttgtaa aactccgttg gattgagata
    12541 acggaaagac aagtcttcta attcccattt gacactggaa atccccaaac gatgggcaag
    12601 cggggcatag atttccatgg tttctttgga aatacgctcc tgcttgtctt ttcgaagatg
    12661 tttcagggtc cgcatattgt gcaagcggtc agacagtttg accaaaataa cgcggatgtc
    12721 ctcagacatg gccatgagca tcttgcgatg attttccgct aattgctcct cgatcgattt
    12781 gtactcgacc ttgccaagct tggtaactcc gtcaacaatc atccgcacat caggaccaaa
    12841 ctctctttcc aaatcgtcca aagtcgcatc tgtatcttcc accacatcat gcaagaatcc
    12901 acaagctact gttacagcat ccagctttag cttagctaaa atacctgcca cttggatagg
    12961 gtgaatgata taaggctcgc ctgatttgcg atattgacca ctgtggcatt caacagcata
    13021 gaccaaggcc ttatggacaa aatgaacatc ctcttccgtt aaatattctt tggttaaagc
    13081 gacaacttct tcgcctgtta aattcacttc tttcggcatc tctactctcc aattcttcct
    13141 accattttat cactttttta agaatatgaa aactagattg gaacagaata agaaaaaaat
    13201 aattcaaaat tgcttgataa ttctgaatta ttggcccata atatactacg aagttagatt
    13261 ttaaacttag gtgatagaag gagagataga agaacggaaa ccatattgta acccaaagac
    13321 tttctgactt cctcaattcc attgaagata cgaaagataa acggtggaac tcgtatcaca
    13381 tacactggta ccttgactgg attttggaat taatactaaa tgaaaatcaa agagcaaact
    13441 aggaaactag ccgcaggtta ctcaaagcac cgctttgagg ttgcagataa agttgacgcg
    13501 gtttgaagag atttttgaag agtataaaaa tcctcaagat actttcttct atcctttagt
    13561 ttataaggag aatacctatg aaaaaaactg ctatttctat ctttgctctc ctaatgttag
    13621 gagtttgctg cctgttccta ttcagccagc aaagctataa aaaacagtcg ttcaatacta
    13681 tgctaacgac cagaacctgc ccagtaggat aacttatagt gaatatagcg acaaatgaga
    13741 agccaactac ggtagcactc taaacatcac gtctatcaaa caagctaatg acggagttta
    13801 tgcaacctat gaagggcaat tgacaccttt ccaatattga taaattgata accagcctgt
    13861 cttcatctag tcatgctggt ttttaagttc attttaaatc cttacctatt ctccctaact
    13921 gtgctatact taatttatac tcaatgaaaa tcaaagagca aactagaaag ctagccgcag
    13981 gctgttcaaa gcactgcttt gaggttgcag ataaagttga cgcagtttga agagattttc
    14041 gaagagtatt agtacattct ttgagattgg agctagtatg aaaatccata aaaccgtgaa
    14101 tcctgttgcc tatgaaaata cctattatct agaaggcgaa aagtacctca tcgtcgtcga
    14161 tcctggtagt cattgggaag ccattcgtca gacaatcgag aagatcaaca aaccgatctg
    14221 tgctattctc ttgacccacg cccattatga ccatatcatg agtctggact tggttcgcga
    14281 gacgtttggc aatcctcctg tctatatcgc agagagcgaa gccagctggc tctacactcc
    14341 tgtcgataat ctctccggtc tccctcgcca cgatgatatg gcagatgtgg tcacaaaacc
    14401 tgcagaacac acctttgtct ttcacgaaga ataccaacta gaggaatttc attttaaggt
    14461 tctgccgacc ccagggcact ctatcggtgg tgtttcccta gtctttcctg atgctcacct
    14521 agtcttgacg ggagatgctc tattccgcga aactatcgga cggaccgacc ttccgactgg
    14581 tagcatggag caactccttc atagtatcca gacccaactc ttcaccctac caaactacga
    14641 tgtctatcca ggacatggtt cagctactac tatcgctcac gaaaaggcct tcaatccctt
    14701 tttttagcaa gatgatgaca atcgaaattt aagtaaacta tccagcaaat ctttctatta
    14761 taaaaggcat cctatcaagg ttttcacacg tgattggatg ccttttttct gatgactaga
    14821 ttttttgtat taccaaataa tcacgcgctc ctctggtgaa cgccacattc cgtctccttc
    14881 tttgacatca taggttgtaa agaaatcgtc gaagtttggt acttgcacat tgacacggag
    14941 tttggctggt gcgtgcacat cgacgctagc caaaagtttc ataaattctg gacgaccttt
    15001 catgcgccag atgcgaccga agttgtagaa gaactcttct gctgagaagt ctgcttctct
    15061 cttagctgct tcaagcgctg ctgcgattcc tcccaagtca gccacgtttt ctgatacagt
    15121 caatttaccg ttaatggttg ctccataaga atcctgtcca tcaaattggt caatgacttt
    15181 ttgtgttttc tccttgaagg cagcatagtc gctctctgtc caccaatcct tgaggctacc
    15241 attttcgtca aaggaagccc cgttagtatc aaaggcatgg gaaatttcat gggcaatcac
    15301 tgccccaata ccaccgtagt tagcagaaga tgactgatgc aagtcataga aaggcgcctg
    15361 taaaatggcc gctggaaaga caatcaggtt cttctgagga ttgtagtagg cattgaccat
    15421 atgagcaggc atgccccatt ccttatagtc tacaggctgg ttccacttac tccaactgtg
    15481 cttgatttcc acacgcgcaa aggctagagc attctcaaaa agactggcag tttcattcac
    15541 taccttatcc ttgtaacgtg caggcaattc ttctggatag ccaatataag gtttgatcac
    15601 attgagcttc acgatagcct gtttacaggt ttctggagtg agccagtcat tcttaagcag
    15661 acgctcctta tagacatcaa tcatggttgc cacttttttc tccacatccg ccttggcttc
    15721 tggagagaac ttctcacggg cgtaccaaag ccccagggct tgcttgaaag gttcttgtgc
    15781 tagatgataa gctgctttga ccttatcttt tgcctctgga actccagaaa gggcacggct
    15841 gtaggcacca gacaaaacac ggatatcctc tgttaaatag ctggttgaaa gattgacaac
    15901 actcaaaatc aaggttgctt taaggagaga ccaggattcc tcactgtaga attgctctgc
    15961 tgcttgccag aaacgttcct cgtctacaat aaccttgtct ggtaattgcc caataactgc
    16021 tttgaagaag tcatccaaag gtagggcagg cgcgaatttc ttgaaatctt cgtaagaata
    16081 tggatgatag agtttagcat attctgaact ttcttcatta gagagtacca ctgccgcaac
    16141 tcggcggtcc aattcaagtc ttttttctag caagtcttca atttcttcat cagagaaatc
    16201 ataagccttg aggagatttg cgctgctttc tttccaaaga gtcaagagct cttcgcgctg
    16261 aggatgttct tctgcatagt aggtcgtatc tggcaagatt gtgcttggag cgctagccca
    16321 tagaacattg attctagcat ccataaagtc tggcgataca ccaaaaggaa ggaagtttgg
    16381 ttttcctgca agctcaaact ctgctagttt agctgtaaaa tccgcaaaag tttccaattc
    16441 ttggaattct ttaaggagtg gtaagacagg tgtgataccg tcagcttctc tcttgtcaaa
    16501 atcacgaact aggcggtggt atttgacaaa gttttccaag atagcatcct caggcacttc
    16561 ttcacctgct aaccacttgt ctgttgtcgc caacatcagg tcttcaattt cctggtctaa
    16621 atcaacaaaa cctcctgttt gagacttatc tgctgggatt tcagctgtct gttgccattc
    16681 tccattgata gcatcataaa aatcatcttg ataacgtgtc atcttgttct cgctttcatt
    16741 tgtatttgca tttatcttaa caaaaatcac tagggaatgc aattaataac catttaacta
    16801 ttatttttta gctattataa aaaatctttc
//
LOCUS       DAVLUM010000046        16088 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLUM010000046 DAVLUM010000000
VERSION     DAVLUM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.046"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            114..2279
                     /locus_tag="VYN42_001401"
     CDS             114..2279
                     /locus_tag="VYN42_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1462463.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKVKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIS"
     gene            2279..3019
                     /locus_tag="VYN42_001402"
     CDS             2279..3019
                     /locus_tag="VYN42_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1462464.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            3168..4655
                     /locus_tag="VYN42_001403"
     CDS             3168..4655
                     /locus_tag="VYN42_001403"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1462465.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHINIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(4701..5978)
                     /gene="ftsY"
                     /locus_tag="VYN42_001404"
     CDS             complement(4701..5978)
                     /gene="ftsY"
                     /locus_tag="VYN42_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1462466.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLESVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGIQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(5982..6800)
                     /locus_tag="VYN42_001405"
     CDS             complement(5982..6800)
                     /locus_tag="VYN42_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1462467.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(6800..7594)
                     /locus_tag="VYN42_001406"
     CDS             complement(6800..7594)
                     /locus_tag="VYN42_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1462468.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            complement(7591..11130)
                     /gene="smc"
                     /locus_tag="VYN42_001407"
     CDS             complement(7591..11130)
                     /gene="smc"
                     /locus_tag="VYN42_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1462469.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLREIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLEEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAASAGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARKVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEVALKTLQDQMARLTESLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLSLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(11121..11819)
                     /locus_tag="VYN42_001408"
     CDS             complement(11121..11819)
                     /locus_tag="VYN42_001408"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1462470.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(12002..12073)
                     /locus_tag="VYN42_001409"
     tRNA            complement(12002..12073)
                     /locus_tag="VYN42_001409"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12038..12040),aa:Arg,seq:ccg)
     gene            complement(12137..13123)
                     /locus_tag="VYN42_001410"
     CDS             complement(12137..13123)
                     /locus_tag="VYN42_001410"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1462471.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(13298..14601)
                     /locus_tag="VYN42_001411"
                     /pseudo
     CDS             complement(13298..14601)
                     /locus_tag="VYN42_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
     gene            complement(14588..>16088)
                     /locus_tag="VYN42_001412"
     CDS             complement(14588..>16088)
                     /locus_tag="VYN42_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1462472.1"
                     /translation="KRSTNEFIGRSAMVTKLLCIYSEGDPFFGVNINSQKEFWNHFVS
                     QTNQGGPYLQNHKIIELVSKTYPELEPSKLGTMLFEYSKLFMENKEDNSTMDSSNNFR
                     HQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTDGNEDQIGFVQFHPSYDYTDFVE
                     GLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGGQDNFDEAWDSYLEYINVAEEKE
                     YITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYELYKDKNYNKQEYYKSGGKTVLE
                     TLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVS
                     TQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLD
                     KELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKP
                     LLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVADDNESDENDDADY"
BASE COUNT         4651 a         3570 c         2874 g         4993 t
ORIGIN      
        1 aagaaagaaa aggaaaaatc aatgttatat tttctgacac taaaaatata acaatttgcc
       61 tttttttact ttttctgata taatgagaga atattcggaa aaggagacta aaaatgaaga
      121 aaaaatttct agcatttttg ctaattttat tcccaatttt ctcattaggt attgccaaag
      181 cagaaacgat taagattgtt tctgataccg cctatgcacc ttttgagttt aaagattcag
      241 atcaaactta taaaggaatt gatgttgaca ttattaacaa agtcgctgag attaaaggct
      301 ggaacattca gatgtcctat cctggatttg acgcagcagt caatgcggtt caagctgggc
      361 aagccgacgc tatcatggca gggatgacaa agactaaaga acgtgaaaaa gtcttcacca
      421 tgtctgatac ttactatgat acaaaagttg tcattgctac tacaaagtca cacaaaatta
      481 gcaagtacga ccaattaact ggcaaaaccg ttggtgttaa aaacggaact gccgctcaac
      541 gtttccttga aacaatcaaa gataaatacg gctttactat taaaacattt gacactggtg
      601 atttaatgaa caacagcttg agtgctggtg ccatcgatgc catgatggat gacaaacctg
      661 ttatcgaata tgccattaac caaggtcaag acctccatat tgaaatggat ggtgaagctg
      721 taggaagttt tgctttcggt gtgaaaaaag gaagtaaata cgagcacctg gttactgaat
      781 ttaaccaagc cttgtctgaa atgaaaaaag atggtagtct tgataaaatt atcaagaaat
      841 ggactgcttc atcatcttca gcagtgccaa ctacaactac tctcgcagga ttaaaagcta
      901 ttcctgttaa ggttaaatat atcattgcca gcgattcttc ttttgcacct tttgttttcc
      961 aaaattcaag caaccaatac actggtattg atatggaatt gattaaggca atcgctaaag
     1021 accaaggttt tgaaattgaa atcaccaacc ctggttttga tgctgctatc agtgctgtcc
     1081 aagctggtca agccgatggt atcattgctg gtatgtctgt cacagatgct cgtaaggcaa
     1141 cttttgactt ctcagaatca tactacactg ctaataccat tcttggtgtc aaagaatcaa
     1201 gcaatattgc ttcttatgaa gatctaaaag gaaagacagt cggtgttaaa aacggtactg
     1261 cttctcaaac cttcctaaca gaaaatcaaa gcaaatacgg ttacaaaatc aaaacctttg
     1321 ctgatggttc ttcaatgtat gacagtttaa acactggtgc cattgatgcc gttatggatg
     1381 atgaacctgt tctcaaatat tctatcagcc aaggtcaaaa attgaaaact ccaatctctg
     1441 gaactccaat cggtgaaaca gcctttgccg ttaaaaaagg agcaaatcca gaactgattg
     1501 aaatgttcaa caacggactt gcaaacctta aagcaaacgg tgaattccaa aagattcttg
     1561 acaaatacct agctagcgaa tcttcaactg cttcaacaag tactgttgac gaaacaacgc
     1621 tctggggctt gcttcaaaac aactacaaac aactccttag cggtcttggt atcactcttg
     1681 ctctagctct tatctcattt gctattgcca ttgtcatcgg aattatcttc ggtatgttta
     1741 gcgttagccc atacaaatct cttcgcgtca tctctgagat tttcgttgac gttattcgtg
     1801 gtattccatt gatgattctt gcagccttca tcttctgggg aattccaaac ttcatcgagt
     1861 ctatcacagg ccaacaaagc ccaattaacg actttgtagc tggaaccatt gccctctcac
     1921 tcaatgcggc tgcttatatc gctgaaatcg ttcgtggtgg tattcaggcc gttccagttg
     1981 gccaaatgga agccagccga agcttgggta tctcttatgg aaaaaccatg cgtaagatta
     2041 tcttgccaca agcaactaaa ttgatgttgc caaactttgt caaccaattc gttatcgctc
     2101 ttaaagatac aactatcgta tctgctatcg gtcttgttga actcttccaa actggtaaga
     2161 ttatcattgc tcgtaactac caaagtttca agatgtatgc aatccttgct atcttctatc
     2221 ttgtaattat cacacttttg actagactag cgaaacgctt agaaaagagg attagttaat
     2281 ggcaaaatta aaaattgatg taaatgattt acacaagcac tatggaaaaa atgaagtcct
     2341 aaaaggaatt acgactaagt tctatgaagg agatgttgtt tgtatcatcg gtccttcagg
     2401 ttctggtaag tcaactttcc tccgtagcct caatctttta gaagaagtca ctagcggtca
     2461 catcactgtg aacggctatg atttaactga aaaaacaacc aatgttgacc acgtccgtga
     2521 aaatatcggc atggtattcc aacacttcaa cctcttccct catatgtctg tattggacaa
     2581 catcaccttt gctcctattg agcacaagtt gatgactaag gaagaagctg agaaattggg
     2641 aatggagttg cttgaaaagg ttggactagc agataaagct aatgccaatc cagatagcct
     2701 atcaggtggt caaaaacaac gtgtggccat agctcgtggc ctagcaatga atccagacat
     2761 catgctcttc gatgaaccaa cttctgccct tgaccctgag atggttggag acgtacttaa
     2821 cgttatgaag gaattggctg agcaaggcat gaccatgatt atcgtaaccc atgagatggg
     2881 atttgctcgt caggttgcca accgcgttat ctttactgca gatggcgagt tccttgaaga
     2941 cggaacacct gaccaaatct ttgataaccc acaacaccct cgtctgaaag agttcttaga
     3001 taaggtctta aacgtctaaa ctcaaactgt aaggatttcc ttgcagtttt tctacctcgt
     3061 attggaattt ttgatttttc ggaaaattat gttagaatta agtttatgaa atgaggtttc
     3121 ctcataccta gcaagactag gaataaaaat agaaattagg tagctagatg tcatctaagg
     3181 ttattgttac aattttcggt gcgagtggag acctggctaa acgcaagctc tacccttccc
     3241 tttttagact atataaatcc ggcaatcttt ccaagcactt tgccgttatt ggaactgccc
     3301 gtagaccttg gagtaaggaa tattttgaat ctgtagttgt cgagtccatc cttgatttgg
     3361 cagatagtac cgagcaagcc caagaatttg ctagccactt ctactatcaa agccatgatg
     3421 tcaatgattc ggaacattat attgctttgc gtcaattaca agctgagctt aatgaaaaat
     3481 accaagctga acacaataag ctcttcttct tgtctatggc acctcagttc tttggaacca
     3541 ttgccaaaca cctcaaatct gaaaacattg tcgatggcaa aggttttgag cgcttgatcg
     3601 ttgaaaaacc atttggtaca gattacgcaa ctgcaaacaa gttgaatgac gaactcctag
     3661 caacatttga cgaagaacaa attttccgta tcgaccatta tcttggtaag gaaatgatcc
     3721 aaagcatctt tgcagttcgc tttgcaaact tgatttttga aaacgtttgg aacaaggatt
     3781 ttatcgacaa tgttcaaatt acctttgcgg agcgcttggg tgtagaagaa cgtggtggct
     3841 actatgacca atccggtgcc ctccgtgaca tggtccaaaa ccacactcta caacttcttt
     3901 cgctcctcgc catggacaaa ccagcaagct tcacaaaaga cgagattcgt gctgaaaaga
     3961 ttaaggtctt taaaaacctc tatcatccaa ctgatgaaga actcaaagaa cactttatcc
     4021 gtgggcaata ccgctctggt aagattgatg gcatgaaata catctcttat cgtagcgagc
     4081 caaatgtgaa tccagaatca acaactgaaa cctttacatc tggtgccttc tttgtagaca
     4141 gcgatcgatt ccgtggtgtt cctttctttt tccgtacagg taaacgactg actgaaaaag
     4201 gaactcatat caacatcgtc tttaaacaaa tggattctat ctttggagaa ccacttgctc
     4261 caaatatttt gaccatctat attcaaccaa cagaaggctt ctctcttagc ctaaatggga
     4321 agcaagtagg agaagaattt aacttggctc ctaactcact tgattaccgt acagatgcga
     4381 ctgcaactgg tgcttctcca gaaccatacg aaaaattgat ttatgatgtc ctaaataaca
     4441 actcaactaa ctttagccac tgggatgaag tttgtgcgtc atggaagttg attgaccgta
     4501 ttgaaaagct ctgggctgaa aatggtgccc cacttcatga ctataaagct ggaagcatgg
     4561 gacctcaagc cagctttgac ctacttgaaa aattcggtgc caaatggact tggcaaccag
     4621 atatcaccta tcgtcaagat ggtcgcttag aataaaaaaa tttcctgcaa gtttatgcct
     4681 tgcaggattt ttgcttctga ttagattaaa ccttccaaga gacctttcat aaagttttct
     4741 gagttaaact ctccaatatc atcgattttt tcaccaaaac caatcaattt tacaggaata
     4801 ttgagttctt cacgaatggc tagaaccaca cctcctcgag cagttccatc aatcttagtc
     4861 aaaacaattc ccgttaaagg tgtgattttc gaaaattctt tggcctgtac tagggcattt
     4921 tgacctgttg atgcatcaag tgccaagaag gtttcatgtg gtgcttctgg cacaacacgt
     4981 ttgataatac gaccaatctt ttccaactca gccataaggt tatccttatt ttgcagacga
     5041 ccagcagtat caatcatgag aatatcgata ccttcagcca cggcacgttc cataccatca
     5101 aagaccacgc tggctggatc agctttttca ggtccagtta ctactggaac atctactcgt
     5161 cggccccatt cagctagctg agctactgca cccgcacgga aggtatctgc tgcaaccagc
     5221 atgaccttct taccagcttg tttgtagcgg tgggctagtt ttccgataga agttgttttc
     5281 ccaacaccat tcacaccaac aaagagcata actgtcaagt tatcttggaa gtggatgctt
     5341 tcatcgtagc taccatcctt ttcataaagc tcaaccaatt tctcaatgat gacacgacga
     5401 agtgcatcag gtttcttggc attttcaagc ttggcttcgt aacgtagttc ctccgttaag
     5461 ttagaagcga cttggatacc aacatcactc ataatcagca gttcttccag ttcctcgaaa
     5521 aattcttcgt caacagagcg gaagttagca aagaaggcat tcaagcgggc accgaaacct
     5581 gtacgagttt tcttaagact gcggtcatat ttttcctgaa cggtttcttc tgcttgaggc
     5641 ctttctggtt caagaacttc agaattattt tcttctatag tctctagaaa ctcagtattc
     5701 ccttcttctg agtgtggaaa ttcttcgact tctttttgag aaacttctac aactgactct
     5761 aaatccagac tttcttcaac tgtgtcttgg atttcctctt cttggaacac agcttgttca
     5821 acaatttcaa cctctgcttc ttcctgagaa acttcctcaa cttctgtgaa ggtaggatca
     5881 acatcttcag acaaatcaag attttccaga gcttctttta caacttcttc gattttaggt
     5941 tcttcttttt ttccgaatag acggtcaaac aatcccatat cttagttctc ctttagcaca
     6001 tattcttcga tagcccaggc gacagcttcc tcatcgttgg tcatcggcgt cactacattt
     6061 gcggctgcct ttacttcagg aacagcgttt tgcatagcaa caccaagacc tgcccattca
     6121 atcatagaga gatcattggc ctcgtcacca caagccatca cttgactttg gtcgattcca
     6181 agatggctga ttagttttgc caaacctgtt gctttatgaa cattctttgg tgaccattct
     6241 agcaacattt cacgtgattt aaagatttca tattggtcaa acaattctgg agaaatcttc
     6301 tgaatggctg catccaaggg ttcttgagca aaggcagtca cgcatttgtt gtaggtcatt
     6361 tgactagata agtcttcaaa gtccactgga acaaaggtca aagctggatt gaatttggca
     6421 taaagacttt cttggtccga ttggatttga taaactgttc cttctgagat ggcatcaaga
     6481 ggcagtgata atttctctgt ttcttcatac aaacgtgcca catcatcata tgaaaagact
     6541 gttttatcaa ggatttctcc tgtatttttc tgaactaatc caccattaaa agtaatggta
     6601 tactcatctt cctgaccgtc agtccctaac tcatggagaa agaaatccat ggcttttaag
     6661 ggacgaccag ttgtcaatac gaccttgata ccacgatcac gcgcagcttt caaggtttcc
     6721 ttggtacgat ccgtcagcct tttatcagta gtcagcaagg tcccgtccaa gtccaatgca
     6781 atcaatttta tatctgccat tataagccct ccatataagc tataaccgac cgttccttat
     6841 ggtgaccaat cacagtcttt gctaattcta aaatttcagg tcgtgcattt tcaggagcta
     6901 caggatgtcc cacaacctgc atcatatgta agtcattaag attgtctcca aaagccatga
     6961 cctgatccat tgtgatacca agttttttag ctaattcaac aatagctaca cccttatcga
     7021 catagtccag aacaatatca atagattcaa agccagttgt catggcctta acaccaggga
     7081 catgttcatt aacccaagct tcaccagctt ctagcgtttc ttctgtgaag ttggttgtaa
     7141 atttgaaaat gtcatctgtg atatcttcca aactcgctac tttttggata ttttcattat
     7201 aatgctgact cactttcaaa taggtctcat caaccgtatc tagaacatat gaacccttct
     7261 tacccgtcaa gagcagttta ttgatatcta cataaggtga cgtcttcagc ttttcaaaag
     7321 ttgccagata aaagtcacga gacatagtcg cttcatacaa gtcctgacct tgatactcta
     7381 ccaaactgcc attttccgcg atgaaaataa tgtcatcacg aacatcagca aataattttt
     7441 ccagagacag aaatccccga cccgaagcca ccgcaaagta aatccctttt tccttgtagg
     7501 aagccaagag agacttgaga cgatccatat caaagcgtcc attcccatct aggaaggttc
     7561 cgtccatatc cgttgctact agtttaattg tcatccttca atactttcta aatcttttaa
     7621 cttaactgaa acaatttttg agacacctga ttcttgcatg gtcactccat agatagaatc
     7681 agccgctgcc atggttccct tacggtgggt tacgacgata aactggctgt ccttgtcaaa
     7741 tcgattgagg taatccccaa aacgtttaac attggcttcg tccagcgcag cctctacctc
     7801 atccaagatg acaaatggga tagtcttaac tcgaatgata gaaaaaagca aagcaagagc
     7861 cgatagagct ttttcaccac cactcatgag gctaagagac tggattttct tacctggagg
     7921 ttgaacagaa atctccacac cagctgttaa aaggtcgccc tcagtcaata tcaagtctgc
     7981 ctgacctccg ccaaacatct gcttgaaggt cactttaaag gactcacgaa tagcttcaaa
     8041 ggttgattta aagcgttcct tgacctcatc attcatctct gtaatggttt caaggagcag
     8101 atttttcgct gacaaaatat catctcgctg actatttaga aagtccagac ggttgtgaac
     8161 ttcttcgtac tggtcaatag cttctatatt gacaggaccc agtgagcgaa tagccttctc
     8221 taaatcctta acttcttgct ctgccagatt gaggttttcc aattcatgcg ctttttctag
     8281 agcttcagta tagctaatct ggtactggtc tgttaattga ctttgtagat ggcgcaagcg
     8341 ctcgctgacc ttttctttct tggcttcagc acgtgtttgc ttgcgaatcc actcctcatt
     8401 ctgctggcga gcctgatcca aatgactagc aatatcatcc agctgacctt ctatatcatc
     8461 caactcaaac tgtttgcgaa tcaaaccttg ttggaagttc gttttctgag ttttggattc
     8521 ttccgcctgt tgactgagca attctgtatc aaccttctca agattgtcaa ccttttcttg
     8581 aagaaggcgc tggatttcct cttgttcaaa atcaagattg tccaattcct tgcctaagcg
     8641 ttcaatatca gccacttcat aacgtttttg cccttgcagt tctgtcttaa gcaaacgagc
     8701 ttgcgctagc tcttcctgca agttttgata gcgttcttgg atggcatttt tgttagactt
     8761 aatctcttca atctcagctt ccagattttg cttgtcactg gcgattgcag caagacgctc
     8821 ttggcagttt tccttgtctg cttgccaatc tccatcagaa agacgatcta tttcctcttc
     8881 ttggagtttc caaagagttt ccagttcttc aacttgctga ctagtttgct gataagcgag
     8941 ggacaagcct tgctcctgaa tacgtgcctg ctctccttga gatttaatag cttctaatga
     9001 ctcggtcaat ctggccatct ggtcttgcaa ggtcttcaaa gccacttctt ctgaacccaa
     9061 gcttgcttct tcttcagcaa tttctttttg taattgctcc agttctggct tgatgaaaat
     9121 actgttattc tgacgattgg ctccacctgc gtaagaacca cctgtgcgca actctgtacc
     9181 gtccaaagtc accatacgaa cctgataacg aactttgcgc gctgctgcac gcgcatgctc
     9241 aacggtatca aaaatcgctg tcgtagctag caagttcttg aaaatagctt ccagtctcgt
     9301 atcgaatgtc accaactcat ctgccatgcc tagaaatccc gcacttgcag cgataacatc
     9361 ttggttctga ctagaaatcg tacgcgcctt gatagtcgtc aacggaagga aggttgcacg
     9421 accagctcta tttcgtttga ggaaatcaat cgccttggtt gccgactctt catcttctac
     9481 gatgatatgc tgactgctgg ctccaagtgc aatctctaag gcagtttgat aatgcacatc
     9541 aaaggtcaaa tgctcactaa cagcaccaat aatcccacca aggcggtctt tttcttggag
     9601 aacactcttt acacctgcat aaaagttact gtgatttcta aggatgtttt ccaaactttg
     9661 agctctagcc tgcttgtttt taagactatc cagacggtca aagagttgac tttgttgagc
     9721 ttgataggaa gttttttgct cctcttgctc cttggcaata gcttgatagt cagccaataa
     9781 tttctgaacc tgctccttgg cagtttcaag ctcttccttt tgctgactag ccttctcttt
     9841 agctatagct aattgctctt ccagcttttc tagttgatct gcttgttttt gagaaagctg
     9901 acgactattt tccaactcat tctcaatacg ggtcaactgg tttgagacat ccgcttcttc
     9961 ttgtaaaaga gctacaaagc gttcacgtaa gagctcaatc atctgatcag gatcgtctga
    10021 gaaagccagc aattcagctt ctaaacgatt gagtttttga ttattttgga ctagatttcc
    10081 ctctaacaga gctaaagagc tttctttatc agacttttct ttgctgagtg aatttctctt
    10141 atcctccaaa gcagccaaac gggcttgtgc ctcctgttga ttcaaggcca cttgctcgga
    10201 ctccagtttc gatagggcta attttctttc taaatcacta atcagactag tcaagtccat
    10261 caaactgcct tggtctttgg ccatttcagc ctgtaaatct tggcgttgct ttttaagagt
    10321 ttgattttct tcttctaatt tttcacgctt ttggtaataa ctcatcaaga gttcttgaac
    10381 ctgagtcaac tcttcttctg tcgactctag ttcagcctta ttttccttga tttgagcaac
    10441 cagaacatct aaataaatag ccttacgttg tccttccaag tctaaaaact tacgggcatt
    10501 ctcagcttgc ttctcaagag gcttgatttg attatccaac tcgtagataa tgtcctctaa
    10561 gcggtccaga ttatcctgag tttgctgcag tttactctcg gtttcttttc tgcgagtctt
    10621 gtattttaaa actccagcag cttcttcaaa aatagctcgt cgttcctcag gcttggaatt
    10681 aaaaatctcc tcaaccttcc cttgggaaat aatagagaag gaatctcgtc ccaatccagt
    10741 atccaagaag aggtcatgaa tctcacgcag acggactttc ttgccgtcaa tcttgtattc
    10801 gctatctcca ctacgataga tatggcgttc caccctgatt tcttgacctg catccttgat
    10861 aaatccgtca tgattatcca gagtcacaac tacagaagca taattgagcg gtttgcgact
    10921 ttcggttcca gcaaagatga catccggcat cttgccccca cggagactct tgacactaga
    10981 ctcccccaaa gcccaacgca gactttctgt aatattggac tttccagatc cattgggtcc
    11041 aacaactgcc gtcacacctt ggtcaaaaac gaccttggtc ttatcagcaa aagacttgaa
    11101 cccctgaatt tcgatttcct ttaaatacat gaatccagcc ctttctcaac ggcatttttg
    11161 gcagcttcct gctctgctaa tttcttagaa cgaccttggc cttgaccgat gctcttacct
    11221 tcaacaagaa cttctacatc aaagacctta tcgtgagcag gccctgtttc agaaatcacc
    11281 tgataacgaa tagccacatc accattgacc tgaagcaact cttggagatg ggttttatag
    11341 tctgtaatca tctcaaattc gcctgcttct accttaggaa tcataacttg gtagataaat
    11401 tccttgacct ttgccacatc cttatccaaa agaagggcac caagaaaggc ttcaaaggca
    11461 tcaccaagaa tggtgtcacg attgcgacca ccagattttt cttccccttt acccaacttg
    11521 ataaactggt caaactggca atcacgcgca aaaccagcta aactctcctc acggacaatc
    11581 atagcacgga gttttgatag gtcaccttca ggctttttag gatatttttt atatagatat
    11641 tctgaaatca ataactgtag aacagcgtct cctaaaaatt ccaagcgttc attgtgtgaa
    11701 atttttaaga ggcggtgctc attggcataa ctcgtatgag taaaggcagt ttccagtaac
    11761 tttttgtctg caaattcgat ttcaaaatga ttctttagta cagtttgtaa ttctttcata
    11821 ccaacttctt tctaactgat aatagtcctt tttattatat caaaaaaagc cccctgagtc
    11881 actctaaaac gggactggaa agcatttggg aattctttag acagagattc tcagttttag
    11941 cggcaaattt gggtcaggat aaagaaaaaa gccctattaa aggcttttta ggatgtttac
    12001 atccaccctg agggaatcga acccccatct caagaaccgg aatcttacgt gatatccatt
    12061 acactaaggg tggaaacttg ttttattata acagaaattt gctctaataa caagtttttt
    12121 ggtcaaagac cccgtcttag tgggaagcat ccccattcca gatggagttt ttcacgatca
    12181 cataatcaac gtgtttaagg tcagcaacct gacgtccacc tgcataagaa atagcacttt
    12241 gaaggtcttg ttccatctca gttaaagtgt cttgcagatg acctttagca ggaagcaaga
    12301 tacgtttgcc ttccacattt ttgtaagcac ctttctgata ttgtgaggct gaaccataat
    12361 attctttgaa ctgttcacca tcgacttcaa tcgttttccc tggactttca atgtgtcctg
    12421 caaagaggga accaatcatg atcatgctag caccgaagcg gatagacttg gcaatatcac
    12481 cgtgagtacg aattcctcca tcagcgataa tcggtttacg cgcagccttg gcacaccagc
    12541 gtagagcagc caactgccaa ccacctgtac caaaaccagt cttaaccttg gtgatacaaa
    12601 ccttaccagg accgattccg accttagtag catctgcacc agcattttcc aattcacgca
    12661 cagcttctgg tgttcccaca tttccagcaa tgacaaaggt atctggcaat tctttcttga
    12721 tgtgttgaat catagaaatc acgctatccg catgaccatg agcaatatca atagtgatat
    12781 actcaggagc atcagccttg agctggctaa caaaatcata ctcataatcc ttaacaccga
    12841 cagatatgga agcaatgagc ccttgatcgt gcattcgttt aataaaagga atgcgtcctg
    12901 cctcatcaaa acggtgcata atgtagaagt aaccaccttt agccagttgc tctgctacat
    12961 tttcatccaa aatcgtctgc atattcgctg gcacaacagg tagtttaaag gtgtgatttc
    13021 ctaaagtgac acttgtatcc gcttctgcac ggcttttaat gacacattta tttggaatca
    13081 attgaatatc ttcgtaatca aaaattggaa attcatttaa catatcgatg tctcgtttct
    13141 tttgtaatga cctacctatg ctctcgcatc actacgcctt ttccgacgtt tccttaattt
    13201 attataaacc aaagtacagt ttttgtcaaa ttattttatg aattaaaata tattgttcgg
    13261 attttgcttg tgttaaaaat aaaagaaaga ggggaaatta ttttctcccc acttcttcat
    13321 caataatcgc tttaaaattt tcttctgaat tttccatcat tttacaaaat gcactataag
    13381 atgaagactt ctgaggaatt tggatagacc atttcttcaa caaagctcca taacctgcta
    13441 ggtttcctat ctcattatca atgaccttgt ccttgctcgg aaaaacaagt ccagccttct
    13501 cagcttttaa aatataagaa taggaaatca gctggaataa gtcctcacgg ttgattcctt
    13561 tttcagtcaa ttccagtttt ttatattttg catctagaac aatctttcgt tctctgtcat
    13621 aaaaatctgg atatactttt cgtttcccaa cagaaaatac tgaaattcca tccgtcttat
    13681 ccttatttct gggatgtaca aaaccttttg gcaacaaggt gtaaacatac tcttcccaaa
    13741 gccaggcaac atcaaagaga ataccataga ttttttgatc ttgataccct aaaccgtgct
    13801 tttcttggtt taggatcatc agacaaagtt cttgtaaatt tctgtactcg tgaaagtatg
    13861 catgacgtat aggtttagat tgatttcccc gaataatctt agcacgatca gctagtttat
    13921 aagagggcgt tacacgcacg atttcagata cgttttcacg actagttgag agattatcta
    13981 gtaccccttg accaatgctt ttctgattct taatgtattc aatagtgtga cggaccaact
    14041 gcatgagggg attatcatag gtgaactctc tcgttgtgta ggcaatattt cccgtgaaag
    14101 gaagattttt cttgagatgg tttcttacat caatcactcc cttaacatga ctgtcgttat
    14161 gagaaaatcg atgatattcc ttataaagac cttttcgaat agcagcttgt agatacttgg
    14221 ggaagagata catcaaaagt tgataaagcc tctcttcacg agacaaagca acatctaaac
    14281 tagtgagatt gatatgaaga accttgttta agagataatg caaaaaatgg tcattactct
    14341 catcagaaaa tcgtgaggaa atcgttaatc tttcctgacc atatccaaga aaaccaatca
    14401 catttcctga ttgatcgttt ccaaaatctt ttgtttctta tccaaatctg gagtatgagt
    14461 caaatcattt ggaaaaatga aaatacgttc atcttgggat agactttcca aggttctgtc
    14521 taaaagaaga ttgcttagtt taggatattc ttcaacaaat ttttctttaa taatcttgtg
    14581 ttgattatca gtaatccgca tcatcgtttt catcgctttc attgtcatca gctactgcct
    14641 gatctttttg ctcattattt gtcagttcaa atgctttttt caaagtttcc aaagtttcaa
    14701 cctcatcata agaacctcgc aagtagtctt ctaggagagg cttaatataa tcagaccaga
    14761 gtaattcata gtcaaaatct acatccttca acttaagaaa ataacttggt ccaatatgat
    14821 aatgactgtt taattcctga acattttcga tagcagcgtt caagtttctg agacgaattt
    14881 ttgcttcttc tgcatggata ttcagctctt tatccaacat gccaacttga ccctcggcag
    14941 taacttcaac aaaacgaaaa cgacgacgca tagcaaaatc aaaggtatcc actgaacgat
    15001 caatatcatt catagttccg atgatgtaaa cattttcggg gatatagaac ttttcatcag
    15061 tttcgtgtag atttgcatat tgggtagaaa cacttccttt ttcaccacga tagccagggt
    15121 cgatagagaa aaagagttcg ccaaaaatct tagaaatctc cccacgattg atttcatcga
    15181 tgatgaagac gaatttctta tcagtatcaa tttctgttgg ggaaacatag tctttcaaac
    15241 caaatctctt tctcaatgtt tctaggacag tttttccacc acttttgtag tattcttgct
    15301 tattataatt tttatcttta tacaactcgt aaacatattt gctaggtagt gaccatcctg
    15361 gaacaccact atcataattt actgacaaat tttgtctact attaacagat aagtaagatg
    15421 tttttgttat atattctttt tcttcagcaa catttatata ttctaagtaa gaatcccaag
    15481 cctcatcaaa attatcttgt cctccaatca attgggtttc ttttgctttc tgacaaaaat
    15541 ctttaaaaat accgtcctgt agcctaaact caatagctcc atccccattt gatactggtc
    15601 ttaaaccttc tacaaaatcc gtataatcat atgatgggtg aaattgtaca aatccgattt
    15661 gatcttcgtt gccatccgtt aattctttgg caatttcttt agcaagataa gtctttcctg
    15721 tgccaggagc accacgaagg ataaggtttg gagactttaa tagagattga gttaattgat
    15781 gacgaaaatt gtttgatgaa tccattgtac tattgtcttc cttattttcc ataaaaagct
    15841 tagaatactc aaaaagcata gttcctaatt tcgatggctc caactcagga taagttttgg
    15901 acaccagttc aattatttta tgattttgca gataaggtcc accttgattt gtctgagaaa
    15961 caaagtggtt ccaaaattct ttctgactat taatatttac accaaagaaa ggatctccct
    16021 cagaatagat acaaagtaat tttgtcacca tagcagaacg accaataaat tcatttgttg
    16081 atcttttc
//
LOCUS       DAVLUM010000047        16084 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLUM010000047 DAVLUM010000000
VERSION     DAVLUM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.047"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            5..958
                     /locus_tag="VYN42_001413"
     CDS             5..958
                     /locus_tag="VYN42_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462473.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            1035..3023
                     /gene="uvrB"
                     /locus_tag="VYN42_001414"
     CDS             1035..3023
                     /gene="uvrB"
                     /locus_tag="VYN42_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1462474.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDVNSLNKQE
                     RKDLVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            3033..3596
                     /locus_tag="VYN42_001415"
     CDS             3033..3596
                     /locus_tag="VYN42_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462475.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            3562..4050
                     /locus_tag="VYN42_001416"
     CDS             3562..4050
                     /locus_tag="VYN42_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462476.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            4124..4591
                     /locus_tag="VYN42_001417"
     CDS             4124..4591
                     /locus_tag="VYN42_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1462477.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(4588..5103)
                     /locus_tag="VYN42_001418"
     CDS             complement(4588..5103)
                     /locus_tag="VYN42_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1462478.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQRLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5115..5642)
                     /locus_tag="VYN42_001419"
     CDS             complement(5115..5642)
                     /locus_tag="VYN42_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1462479.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(5924..6487)
                     /locus_tag="VYN42_001420"
     CDS             complement(5924..6487)
                     /locus_tag="VYN42_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1462480.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(6471..7022)
                     /gene="coaC"
                     /locus_tag="VYN42_001421"
     CDS             complement(6471..7022)
                     /gene="coaC"
                     /locus_tag="VYN42_001421"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1462481.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(7034..7723)
                     /gene="coaB"
                     /locus_tag="VYN42_001422"
     CDS             complement(7034..7723)
                     /gene="coaB"
                     /locus_tag="VYN42_001422"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1462482.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGYEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7953..9623
                     /locus_tag="VYN42_001423"
     CDS             7953..9623
                     /locus_tag="VYN42_001423"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1462483.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDTIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            9951..11126
                     /gene="mutY"
                     /locus_tag="VYN42_001424"
     CDS             9951..11126
                     /gene="mutY"
                     /locus_tag="VYN42_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1462484.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            11181..11885
                     /locus_tag="VYN42_001425"
     CDS             11181..11885
                     /locus_tag="VYN42_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462485.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            11878..13227
                     /gene="vicK"
                     /locus_tag="VYN42_001426"
     CDS             11878..13227
                     /gene="vicK"
                     /locus_tag="VYN42_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1462486.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            13229..14038
                     /locus_tag="VYN42_001427"
     CDS             13229..14038
                     /locus_tag="VYN42_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1462487.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            14129..14371
                     /locus_tag="VYN42_001428"
     CDS             14129..14371
                     /locus_tag="VYN42_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1462488.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            14373..14627
                     /locus_tag="VYN42_001429"
     CDS             14373..14627
                     /locus_tag="VYN42_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1462489.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            14702..>16084
                     /locus_tag="VYN42_001430"
     CDS             14702..>16084
                     /locus_tag="VYN42_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEV1462490.1"
                     /translation="MTIDISEESLAKESADLLKILLKDRTTKKSIVWATHSYELLGKG
                     FAPSDRINPSKVTGNFANLIQPRSEKSKYEQKDRTKIRAEVFTPTWLVAKQNGYVESK
                     LGSLSLEEYVDLRWLEVTCGEAPYMVTRYDTVTGEEIPLSERVGFVDRKLQRISREVS
                     DEVTFYKLVKDAYHASYGYEYQGDSLLLARENLLATFEDYYLAKTGNQPTLEKKKEIA
                     TIISYNVFQMDGLKKSSPYSAKQKQSQQLSLFADELEVQEVEESKTHIKDWKKNRMIG
                     FERLSSEESEMKFDVVIGNPPYQETGEARDEPIYHYFIDEAYKIADKSILITPARFLF
                     KAGQTPKNWMEKMLEDKHLKVQFYELKSGKVFTGTDIKGGVAITYRDVDKDLGPIGVF
                     TIFETLNGIVKKIEKHPEFETFSDLVYPQGIYRFSNKLFSDYPNAEKLQGKGTKNKIV
                     SKSLTQLDFVF"
BASE COUNT         4943 a         2786 c         3586 g         4769 t
ORIGIN      
        1 ggatatgaag aacaaaagaa tatttaaaga cttccaagct tcaaaaatga gtttaaacat
       61 ttacacaagc cccttgttag cctttgtttt tgtcttcata ggagagtttg tggcttatac
      121 tttatatggt attagtttgt tagctctcat cggacttgct agaaattttg gagaggctgg
      181 tcaaaatctt gcaagctact tgcagacctt gcatcagagc ttgacggata aaacaagtga
      241 ctttcgttta attttaggat tactggcctt tggttttatt cttaacactg tgttcagatg
      301 gacaagaaaa gttgagaaaa gacctattcg aaccttggga ttttatagag agaatttcct
      361 cagcaatctt ctgaaaggat ttagtctagg cctggcactt tttcttctga ccttgttagg
      421 tttagtagtc ttaggtcaat atcgtttgga atccattcac ttgaatcctt attctcttgc
      481 ctttgtcgtc tttactatcc cattttggat tttacagggg acagcagaag aagtggtggc
      541 ccgtgcttgg ctacttcctc aattggcctc aagaaccaat ctaaaactag ctattcttat
      601 atctagcctg ttctttaccc tgcttcatat gggcaattct ggtctcaccc ctctatctct
      661 agtaaatctc tttttattcg gagttgccat ggctctttac cttctcaaaa ctgatacagt
      721 ttggggtgtt gcaggtattc atggtgcttg gaattttgct cagggtaatc tctttgggat
      781 tttagttagt ggtcaaccgt caggaacgtc tctgatgacc tttttaccac aaggcaatca
      841 agattggcta tcaggtggtt cttttggcat agaaggttcc attatgacaa gtctggtatt
      901 actactgctg attgtctatc ttgctaataa attaaagaaa gaaaatgaaa ggatgtgact
      961 tcggtccatc cttttcttcg tgaaaatact ataagtatgc taaaatagga atagcacatg
     1021 gagagaggat tcttatgatc aatcacatta cagataatca atttaaacta gtatcaaaat
     1081 atcaaccatc aggagatcaa ccccaagcta tcgagcagtt ggtggataac attgaggggg
     1141 gagaaaaagc acagattctg atgggggcga ctggaacagg gaagacctat actatgagtc
     1201 aggtcatttc taaagtcaat aaaccaactc tggttattgc ccacaataaa actctggctg
     1261 gtcagctcta tggggagttt aaggaatttt tccctgaaaa tgcagttgag tatttcgtat
     1321 cctactatga ttattaccag ccagaggcct atgtcccttc tagcgatacc tatattgaga
     1381 aggatagttc tgtcaatgac gagattgaca agcttcgcca ctcagctacc tcagcccttt
     1441 tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg tatctatggt ttgggttcgc
     1501 ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg tctagagatt tctcgtgata
     1561 aactcttgaa tgacttggtc gatattcagt ttgaacgcaa tgatattgat ttccaacgcg
     1621 gaagatttcg cgttcgtggg gatgtggtag agattttccc agcttcccga gatgaacatg
     1681 cctttcgagt agaatttttt ggagacgaaa ttgaccgtat tcgtgaagtt gaggctctga
     1741 caggtcaggt gttgggagaa gtggatcatt tagcgatttt cccagcgaca cactttgtga
     1801 ccaatgacga ccacatggaa gttgccattg caaagattca ggccgagttg gaagaacaat
     1861 tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca gcgtttgaaa cagcggacag
     1921 agtatgatat cgaaatgttg cgtgagatgg gctataccaa cggggttgag aactattcac
     1981 gacacatgga tggacggagc gaaggagagc ctccttatac gctcttagat ttcttcccag
     2041 atgatttttt aattatgatt gacgagagtc acatgaccat ggggcaaatc aagggcatgt
     2101 acaatggaga ccgttcgcgt aaggaaatgc tagtaaatta tggtttccgt ttaccgtctg
     2161 ccttggacaa tcgtcctctc cgtcgtgagg agtttgaaag ccatgtgcat cagattgttt
     2221 acgtatcagc gacacctggt gactatgaaa atgaacagac tgagacggtg attgagcaaa
     2281 tcattcgacc gacagggctt ttggatcctg aggtggaagt ccgtccgact atgggacaga
     2341 ttgatgatct cttaggtgaa atcaatgccc gtgttgaaaa gaatgaacga acctttatca
     2401 ccaccttgac caagaaaatg gcagaggact tgaccgacta cttcaaggaa atgggtatca
     2461 aggttaagta catgcactcg gatatcaaga ccttggaacg gacggagatt atccgtgacc
     2521 tgcgcttggg tgtctttgat gtcttggtcg gaattaacct gctccgtgaa ggaattgacg
     2581 ttcctgaagt gagcctcgta gctattctcg atgctgacaa ggaaggtttc cttcgcaacg
     2641 aacgtggact catccagact attggacgtg ctgctcgtaa cagtgaaggc catgtcatca
     2701 tgtatgcaga cacggttacc cagtctatgc aacgtgctat cgatgaaact gcccgccgtc
     2761 ggaaaattca gatggcctat aatgaagaac atggtatcgt tccacaaacc attaagaaag
     2821 aaatccgtga cctgattgcc gtaactaagg cagttgctaa ggaagaagac aaggaagttg
     2881 atgttaatag cctcaacaaa caagaacgta aagatcttgt taagaaactc gaaaaacaaa
     2941 tgcaagaagc cgtcgaagtg cttgactttg aactagcagc acagattcgt gatatgatgt
     3001 tggaagtcaa ggcgttggat taggggaata gtatgattta tttaagaaag ttaaagagag
     3061 aagatttgat gtctttatgg gaaatggctt attcacaact taatccagtt tggaaacagt
     3121 atgatgctcc ctattatgat gattatcagt atttttcaaa ttttaaagaa ttcgaactac
     3181 aaaaatcaga atccatttta agcaactcaa atcgccttgg tatttttgtt gatgataaac
     3241 tagttgggac tgtttcgcgt tattgggtat gtaaacaaac aagatggatg gaattgggaa
     3301 ttggtattta tgataaaaaa ttctggaaca ctggtattgg gaaagttgct atgttgcagt
     3361 ggatagatag gacgtttcag gattacttgg agttggagca tctgggtttg acaacttggt
     3421 cagggaatct tggtatgatg aaacttgctg aaaaattaag aatgaaaaaa gaagctcata
     3481 ttccaaaagt tcgttattat caaggtaaat attttgatag tattaaatat ggtattttga
     3541 gagaagactg ggagaaaata aatgacggtt attatcaaat caatggaaac tcctgaagag
     3601 atagaaggta aatccctcgt tcactggcaa acgtggagag aggcttatga tgaccttttg
     3661 cctgcggaat ttcaggatac aatgacatta gaaagatgtc gattctttag tcaaaagtat
     3721 ccagaaaata cattgattgc gatggatggc gtgaaggtgg ttggttttat cagttatggc
     3781 aattttcgtg atgagactat tcaagctggt gaaattattg ctttatatgt tttaaaagac
     3841 tattatggaa aaggtatcgc acaaaagtta atgaaagcag ctttgactgc tcttaatcat
     3901 ttttctgaaa ttttcttatg ggtattgaaa gataacaagc gcgccattgc tttctatcaa
     3961 aaaatgggtt ttacttttga tggacaagaa aaaatacttg aacttggaaa gcctataaag
     4021 gaaaaacgaa tggtgttcta ttctaaataa ttttaaaaaa gtaaaagata atatctctgg
     4081 tagtaagtct gaaaatttaa taaattagaa agcgagtaaa tttatgtccc gttcccaatt
     4141 aacaatttta acaaatatct gtctgattga agacctcgaa actcagcgcg tggtgatgca
     4201 gtatcgcgcc cctgaaaaca atcgctggtc tggttatgcc tttcctggag gtcatgtaga
     4261 aaatgatgag gcttttgcgg agtctgtcat tcgtgaaatc tacgaagaaa cagggttgac
     4321 tatccaaaat cctcaacttg tcggcattaa aaattggcca ctagatacag gtgggcgcta
     4381 tattgtcatt tgttataagg cgactgagtt ctctggtacc cttcaatctt cagaagaggg
     4441 agaagtttct tgggtgcaaa aagaccagat tccaaactta aatctggcct atgatatgct
     4501 accattgatg gaaatgatgg aagctcccga caagtcagag tttttctacc ctcgccgtac
     4561 agaagacgat tgggaaaaga aaatcttcta gtcttttact aaataaccta gctgatccaa
     4621 ggcctcctcg atatagtgga ggtcttgttg tgtttcggct tcgactaggt ggtaatggat
     4681 gccatctgtc aattcagata gaggtctaaa gtcagaatgc tcgacttgtt ctagaaaatg
     4741 ttgcacatct ctgcgacaag acagtttaag caaggtttca atttctccat aaacgggatg
     4801 gtcaatcaag gtattctgga catgcccacc attatcgaca atagcaagga gttcctgacc
     4861 gatttcttca acttcatgtt tcactttgaa aagtttgtga acataaggat tggtatcaat
     4921 ttgcttatag atataaccac gattggtaga tagaattgga gctccatcag ctcttaaaat
     4981 tgcaatatct tgaacaataa cttgtcgagt gacatgaaag tgctcagcta atctttggcc
     5041 attgagggct ttaggagctt ctttcaagag ttggagcagg gcttgtttgc gatcttttgt
     5101 catagttctt ccttttaacg gcgttttcga agcactttat agacagctag tgctaatgta
     5161 tagtctacca tactatggat aattgtgcca aatccaacta gtacaaatag aacatagaac
     5221 atattttcta cattggtacc cgaagttgcg taaaaaagga cacaggctaa tacttcagca
     5281 agggcatgaa caacagccaa aacaaaattg aaaacccagg aagattttgg tttatctagg
     5341 gtatcgggga atttttgtag gtaaagagct cctaaagcac caaaagatat atgggaaaaa
     5401 gcccgaaaaa cgataaccat gggatagcca gccatcaaaa atccaaaact agaggctagg
     5461 atgacaaaaa ctgccatcaa gggcgacaag aacatggcta taaaaatagc gatgtggctc
     5521 cccaaagtat aggaagcagg tggaatgaca atcttgaaag gcataacaat tggaatcaaa
     5581 atcgcaatag ccgttaaaag ggctgtcatt gtcataaatt gtgtcttttt ccgtgtattc
     5641 acaagaatct cctttttaac tgcatataca ctagtatggt acaataaacc agacaataaa
     5701 gcaagaattt acttgggttt atagatcatt ttttagttaa aagttatagt agatggaaac
     5761 tagaatagtc cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgatcg
     5821 atttgtcctg ttcttatttc gttttactat agtaaagatt tcattaaaaa gaaactgtat
     5881 agagcaaaat ctccaccttc aggtttgaaa gcggagattg tttttatttt ttcaaggttt
     5941 gtagtcgtgg aacaatggct agggttagaa ttgcagaaat gaccaattca gcaattgaat
     6001 ttgttgagat aacggttgcc agaagaagtt ggatatttcc attataaaca tttccaaata
     6061 ggaagaagat tcctccaagg acaaagatag tatttgtcaa ggaaccaagg gctccagcta
     6121 aaatcagacc agtcttgttt ttcatcagtt tatagactaa gtaaggagtt aaaccaatca
     6181 aaatacgtgg gacgatggca atgatagctg agtagatgtt tccgtttggt acgaagggag
     6241 agaagaggta gcttgtcggt agaatcgtaa tcgtgttaac cgtcaagcta agtaatccca
     6301 tcaaaaatcc aagtgtaacc ccaactcgtg gaccataaat aatgctggca ataatgacag
     6361 gaatatgaac aatggtcggt ttgattggaa atggaaaaag gttaaagata agtgagctca
     6421 gaaagtgtat cacgagcatg gtagcaaaaa agatagcaat gggtgcaata ttagagcgtt
     6481 ttttcatcga tagtttcctt tattctttct aaaataattg tgaggtcagc taaagctcct
     6541 cgtccgtggt ctccacaagc tagtagggat tccttaggag caatcagctg atagccgtag
     6601 gtttctaatg ttttcagatt attctgagtt actggatggt catacatttt tgtattcata
     6661 gcaggagcta ttagtttggg aatatgactt ggtagggcta gagctgtact ggttaccatg
     6721 ttgtccgcaa atccgtgagc tagttttgca atagtgttag cagttgcagg taccacgata
     6781 aataaatctg ctttttttcc aagttcgata tgattgacct gatcaggata gggttccttc
     6841 atgacatcca agtggacagg attctgtgag agtacctgta gtgtcaaagg ttggataaac
     6901 tctgtagcag cctgagtcat taagacagtg acttgatggc cttgtttttt tagagaactg
     6961 actaaatctg ccgacttata agaggcgatt gaacccgtta cagccaagag aatgtttgcc
     7021 atagttttcc tttctaagaa tgataggctt gaattttttc aaggaggagt tctgcaattt
     7081 cttctttagt ctggactgtt tgaagctgat ttttctcaac aaatatagct cggtgctgat
     7141 ctgttgaaat ttgagtcagg tcattcgcga tgattaaatc tgcttgattc ttgataagac
     7201 tttttcgtgc aatgtcaacc agatgatctt cggtaacatc aaccagcagt ttgaaaccaa
     7261 tcagatgaat agtaggattc cattccttga ctagggatat gattttgggt gtctttttaa
     7321 ggaacaaaac ctgaacctca tcagttgaag aaatcttggc ctgatgattt tgcttgctta
     7381 aaaattcttt tagattggag ctagcctgaa cttcctcaag ccctgtcata taaacaggag
     7441 tgtagtcaga aacagccatt gagtggatca agacctgata atcctgaaca cgttcttgca
     7501 tttctattag aaggtccttg gtattggtaa tttctcgaat acttaggtta ggatgaggct
     7561 ctggcttcag agctcgtttt gtcgtaatta aacaaacttc ataccctgca gaaagcaaag
     7621 tctctgtgat aattttcccc aagtgacctg tagaatggtt agtgatagag cggacgctat
     7681 cgatagcttc actggtaccg cccgatgtaa ctaaaatttt catagcacta ttgtacacaa
     7741 aaataagcgg taagtaaaat gaaagtgata aatttttggt aaaaacgaag atttattata
     7801 gtttcaaact ataaagccat ataaaattta agaaaggact ctaaaagtct taaaaacaga
     7861 gatatttacg aacgtttaga gagttttagg atgttaaaaa tcttgttttg tgatataatg
     7921 aattatcata taagaggtta gaggaatttt gaatgaaaac agatattgaa atcgcacaga
     7981 gtattgagtt gaagccaatt gttgatgttg tagagaaact tggtatttct tatgacgatt
     8041 tggagttgta cggaaagtac aaggctaaac tcagctttga taaaattcgt gcagttgaga
     8101 gcaatccagt cggtaaattg atcttggtta ctgccatcaa cccaacacct gcaggtgaag
     8161 gaaagtcgac gcttaccatt ggtcttgcgg atgccttgaa caagattggc aagaaaacca
     8221 tgattgctat ccgcgaaccg tctcttggtc cagtcatggg gatcaagggt ggtgctgctg
     8281 gtggtgggta tgcacaagtt ctgccaatgg aagacatcaa cctccacttt actggagata
     8341 tgcatgctat tacaactgcc aacaatgccc tttctgcctt gattgacaac cacttgcacc
     8401 aagggaatga gctggaaatt gatcaacgtc gtatcctctg gaaacgcgtt gtggacttga
     8461 acgaccgtgc gctccgccat gtgactgttg gtcttggtgg tcctctaaac ggtattccac
     8521 gtgaggatgg ttttgatatt acagttgctt cagaaatcat ggcaattctt tgcttggcaa
     8581 cggacatcga ggacttgaaa cgtcgtttgg cgaatatcgt tattggttat cgctatgacc
     8641 gtacgcctgt ttctgtaggt gatttgcagg ttgagggtgc cttggctttg attttgaagg
     8701 atactattaa gccaaacttg gttcagacaa tttacggtac acctgccttt gtacacggtg
     8761 gtccatttgc caatatcgct catggctgta actctgtttt ggcgacgaca acagcccttc
     8821 acttggctga ttacactgtt actgaagctg gttttggtgc ggaccttggt gctgagaaat
     8881 tccttgatat caagacacca aacttgccaa catctccaga tgcagttgtt attgtcgcaa
     8941 cccttcgtgc ccttaagatg aatggtggtg tggctaaaga cgctctgact gaagaaaatg
     9001 tagaggcagt tcgtgcaggt tttgctaact tgaaacgtca cgttgaaaat atccgtaagt
     9061 tcggtattcc agcagttgta gctattaacg aatttgtatc tgatacagaa gctgaaattg
     9121 cagccttaaa agaactctgt gcctcaatcg atgtaccagt tgaattggct agtgtctggg
     9181 ctgatggagc agaaggtgga gtagcacttg ccgaaacagt tgttaagaca attgctgaaa
     9241 atccagctaa ctataaacgt ttgtacgata atgacctttc tgtccaagaa aagattgaaa
     9301 aaattgtcac tgaaatctat cgtggtagca aagtgaactt tgagaagaaa gctcaaacac
     9361 aaattgctca aatcgttcaa aacggttggg acaaattgcc aatttgtatg gctaaaactc
     9421 aatacagttt ctcagacaat ccaaatgcgc ttggagcacc agaaaacttt gaaattacca
     9481 ttcgtgaatt ggtaccaaaa ttaggtgcag gcttcatcgt tgccttaact ggtgatgtta
     9541 tgaccatgcc aggtcttcca aaacgtccag cagctctcaa catggatgtt gaaagcgatg
     9601 gaactgtact aggcttgttc tagtggattg aaattgactt taagtgagtt tggaaataat
     9661 atccaagctc attttttctc agactgcaag cagttcatca ataagattta tactcttcga
     9721 aaatcttttc aaactacgtc agcttcacct tgccgtaggt atatgatact gactctgtca
     9781 gttctatcca caacctcaaa acagtgtttt gagcaacctg cggctagctt cctagtttgc
     9841 tctttgattt tcattgagta taagtagata gaaaagttat atactatcta ttgaaaatat
     9901 tataaatcag atacaaagac aggtgaaacc ttctgtgtta tactagagat atgttagatt
     9961 tgaaagaata cggtatcgtc atgtggccgg aggagaaagt catttctttc cgtgagaaac
    10021 ttctcgcttg gtatgatgaa aacaaaagag atttgccttg gaggagaagt aaaaatcctt
    10081 atcacatctg ggtatctgaa atcatgcttc agcagaccag ggtggataca gttatccctt
    10141 actacgaaag atttttggac tggtttccaa ctgtcgaaag tctggcaact gcgcctgagg
    10201 agagtttact gaaagcttgg gagggcttgg gctattattc tcgagttcgc aatatgcagg
    10261 ctgcagccca gcagattatg actgactttg gtggccaatt tccaaatacc tatgaaggaa
    10321 tttccagctt gaaagggatt ggaccttaca cagcaggagc catttccagt attgctttta
    10381 acttgcctga gccagctgta gatggtaatg tcatgcgggt cttggcgcgt ctgtttgaag
    10441 tcaaccacga tattgggatt ccaagtaatc gaaaaatttt tcaggcaatg atggagatct
    10501 tgattaatcc agatcgtccg ggtgatttta atcaagcctt gatggactta gggtctgata
    10561 ttgagtctcc tgtaaatccc agacctgaag aaagcccagt caaggacttt agtgcggcat
    10621 atcagaatgg aaccatggac cgttatccaa ttaaatctcc taagaaaaag ccggttccta
    10681 tttatcttaa agccttagtt gtgaaaaatt ctcaaggaca atttttactt gaaaaaaatg
    10741 aaagcgaaaa gctcttggca ggtttttggc atttcccctt tatagaagtt gataactttt
    10801 cgcaagaaga gcagtttgac ctctttcatc aggttgcgga agaaagtgtg aactctggcc
    10861 ccagtccaga agagagtttc cagcaggact atgacctaga tgttgattgg cttgatgttt
    10921 gttttgatac agtccagcat gtttttagtc atcgaaaatg gcatgtacag attgtagcag
    10981 gtcaggtgag tgacttccat gatttttcag atagggaagt tcgttggctt tcaccagaag
    11041 aattcaagaa ttacccactt gccaaacccc aacaaaaaat ctggcaggct tatgcacaag
    11101 ccaacttaga cagtagccaa gactagctat tgtgtcttct gactattttt tggtataata
    11161 gtagagaaaa aggtgaacat atgaaaaaaa tactaattgt agatgatgag aaaccaatct
    11221 cggatattat caagtttaat atgaccaagg aaggttacga agttgtaact gcttttaatg
    11281 gtcgtgaagc gctagagcaa tttgaagcag agcaaccaga tattattatt ctggatttga
    11341 tgcttccaga aattgatggt ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc
    11401 ccattcttat gctttcagcc aaagatagtg aatttgataa ggttatcggt ttggaacttg
    11461 gggcagatga ctatgtaacg aaacccttct ccaatcgtga gttgcaggca cgtgttaaag
    11521 ctcttctgcg tcgttctcaa cctatgccag tagatgggca ggaagcagat agtaaacctc
    11581 aacctatcca aattggggat ttagaaattg ttccagacgc ctacgtggct aaaaaatatg
    11641 gcgaagaact agacttaacc catcgtgaat ttgagctttt gtatcattta gcatcgcata
    11701 caggtcaagt catcacgcgc gaacacttgc ttgagactgt ctggggttat gactattttg
    11761 gtgatgtccg tacagttgat gtgactgtac gacgtctgcg tgagaagatt gaagatacgc
    11821 ccagccgacc agagtatatc ttgacgcgcc gtggtgtagg gtattacatg agaaataatg
    11881 cttgatttac tgaaacaaac catttttacc agagatttta tctttatcct gattttgtta
    11941 ggtttcatcc ttgttgtgac cctcttatta ctggaaaata gacgtgataa tattcagttg
    12001 aagcaaatca atcaaaaggt taaagatttg attgcaggag attattccaa ggttcttgat
    12061 atgcaaggtg ggtctgaaat cactaatatt accaataatt tgaatgactt gtcggaggtt
    12121 attcgtctca ctcaggaaaa tctagaacaa gagagtaaga ggctaaatag tattctgttt
    12181 tatatgacag atggggttct tgcgaccaac cgtcggggtc agattatcat gattaacgat
    12241 acagccaaga agcaactggg gttggttaag gaagatgttc tgaatagaag cattttggaa
    12301 ttgctcaaga tagaagaaaa ctatgaattg cgtgatttga ttacccaaag tccagaattg
    12361 ttgctagatt cccaagatat caatggcgaa tatttgaacc ttcgagttcg ctttgccttg
    12421 atacgtcgag agtctggctt tatttcaggt ttggtggctg ttttgcatga tacgacggag
    12481 caggagaagg aagaacgcga acgaagactc tttgtttcca atgttagcca tgagttacgg
    12541 actcctctga ctagcgtaaa atcctatctt gaagccttgg atgagggggc tttgtgtgaa
    12601 actgtagcac cagactttat caaggtttct cttgatgaaa ccaaccgtat gatgcgcatg
    12661 gtgacggatc tcctccatct ttcacgtatt gataatgcta ccagtcacct agatgtggaa
    12721 ctgattaact tcactgcttt tattaccttt atcctcaatc gttttgacaa gatgaaagga
    12781 caggaaaagg agaaaaaata tgagttggtg agagattatc ccatcaattc tatctggatg
    12841 gaaattgata cagataagat gacgcaggtt gtcgacaata ttttaaataa tgctattaag
    12901 tattcgccag atgggggtaa aatcactgtc agaatgaaga caactgaaga ccagatgatt
    12961 ttatccattt ctgaccacgg tttggggatt cctaagcagg atttaccacg tatctttgac
    13021 cgtttctatc gtgtggatcg tgctagaagt cgtgcacaag gtggtacagg tctaggactg
    13081 tctatcgcta aagaaattat caaacaacat aagggcttta tttgggccaa gagtgaatac
    13141 ggcaagggtt caacctttac cattgtgctc ccttatgata aggatgcagt gaaagaagaa
    13201 gtatgggagg atgaagtaga agactagaat gagtgaaata ggctttaaat acagtatttt
    13261 agcgtcgggt tccagtggaa attcttttta tctggaaacc tcaaaaaaga agcttttagt
    13321 agatgcaggc ttgtctggca agaaaattac cagtctgcta gctgaaatta accgtaagcc
    13381 agaagacctg gatgccatct tgattaccca tgagcattca gatcatatcc atggagtagg
    13441 cgttttggct cgcaagtatg gtatggatct ttatgccaat gaaaagacct ggcaagctat
    13501 ggaaaatagt aaatatcttg gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg
    13561 taaaaccaaa acctttggag atatcgacat cgagagtttt ggtgtaagcc atgatgcagt
    13621 cgcaccgcag ttctatcgct ttatgaagga tgataagagt tttgtcctct tgacagatac
    13681 aggttatgtc agtgaccgta tggcgggcat tgtcgaaaat gcggatggtt atcttatcga
    13741 ggccaaccat gatgtagaga ttttgcgatc aggttcttac gcttggcgcc tcaaacaacg
    13801 aatcctatct gaccttggtc acctttctaa cgaggacggt gctgaagcta tgattcggac
    13861 gctaggaaat cgtactaaga agatttacct tgggcattta tctaaggaaa ataatatcaa
    13921 ggaactggct catatgacca tggtcaatca gctggctcaa gctgatctgg gagtcggagt
    13981 agactttaag gtttatgata cctcaccaga taccgcaaca ccattgacag agatatagaa
    14041 agaacgctga gaaggtgttc tttttatatt gactggacac ctaaaaagta atacaatggt
    14101 gttaccatta aaaaagggag cacaaaagat gactactatt acattaaaag tttctgaagc
    14161 tgataaaaca tttatgaaag caatggctaa gtttgaagga gtttcccttt cggaacttat
    14221 tcgcaccaaa actcttgaag ccctagaaga tgaatacgat gctcgtgtgg cagatttagc
    14281 ctatcaagag tatttagaag acttggaaaa aggagttgaa cccattactt gggaagaaat
    14341 gatgcatgat ttaggcttga aggatgaata atttgtataa attagttcca acaagacgtt
    14401 ttatcaagca attgaaaaaa ttggaccgtt atacgcagaa gctaattaca aactatttac
    14461 aaaccaatgt tttggaagat ccaagacgac acggaaaggc tttggttggt aatcgcgttg
    14521 gtcaatggcg ctatagaatt ggtaattatc gagttatcgt acaaattgta gatgatgaat
    14581 tagttgttgc tactctagaa gttggtcatc ggagagatat ttattgaatt acttttttca
    14641 agtaaatttt cattctttaa aatatgatat aatagggctt acaatataag agaggttgct
    14701 gatgacaata gatattagtg aagaaagttt ggctaaagaa tcggctgact tattaaaaat
    14761 tcttttaaaa gatcgaacga caaagaaatc aattgtttgg gctacgcatt cttatgaatt
    14821 gttaggaaag ggatttgctc caagtgatcg catcaatcca agtaaggtta ctggaaactt
    14881 tgccaacttg attcagccca gatctgaaaa atccaaatat gaacaaaaag atcggacaaa
    14941 aataagggca gaagtgttta caccaacgtg gttggtcgca aagcaaaatg gatatgtaga
    15001 atcgaaatta ggctcgttaa gtcttgagga gtatgtggac ttacgatggt tagaggtaac
    15061 ttgtggtgaa gcaccttata tggtaacgag atatgatacc gtaactggtg aggaaattcc
    15121 attatctgag cgagttggtt ttgttgatag aaaactgcaa cggattagtc gtgaggtttc
    15181 agatgaagtc acattttata aacttgtaaa agatgcttat catgcttcgt atggttatga
    15241 gtatcaagga gattctctcc ttttggcgcg tgagaatctt ttggcaactt ttgaggacta
    15301 ttatctagct aagactggaa atcaaccaac attagagaaa aagaaagaaa ttgcgactat
    15361 tatctcttac aatgtctttc agatggatgg attgaaaaaa agtagtcctt attcagctaa
    15421 acaaaagcaa tctcaacaat tgagtttgtt tgcggatgag ctagaagtcc aagaagtaga
    15481 agaatctaaa acccatatca aagactggaa aaagaataga atgataggtt ttgagcgcct
    15541 atctagcgag gaaagtgaaa tgaaatttga tgtcgtgata ggaaatccgc cgtatcagga
    15601 aacaggagaa gccagagatg agccgatata tcactatttt attgatgaag cttataaaat
    15661 cgcagataaa tctatactaa tcaccccagc aaggttttta tttaaagctg gtcaaactcc
    15721 taaaaattgg atggaaaaga tgcttgaaga caagcattta aaagttcaat tctatgaact
    15781 taaaagcggt aaagtattta caggaacgga tattaagggt ggagtagcaa taacttatcg
    15841 tgatgttgat aaagatttgg gaccaatcgg agtatttact atttttgaaa ctttgaatgg
    15901 tattgtaaaa aaaatcgaaa aacatccaga atttgaaact ttttctgatt tagtttatcc
    15961 tcaaggtatt tatagatttt caaataaact tttttctgat tatccaaatg ctgaaaagct
    16021 gcaaggaaaa gggacaaaaa ataaaattgt ttcgaaatca ctaactcagt tagattttgt
    16081 tttc
//
LOCUS       DAVLUM010000048        15738 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLUM010000048 DAVLUM010000000
VERSION     DAVLUM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.048"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            169..1956
                     /locus_tag="VYN42_001431"
     CDS             169..1956
                     /locus_tag="VYN42_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1462491.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            1953..2429
                     /locus_tag="VYN42_001432"
     CDS             1953..2429
                     /locus_tag="VYN42_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1462492.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            2457..3362
                     /locus_tag="VYN42_001433"
     CDS             2457..3362
                     /locus_tag="VYN42_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1462493.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAQKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            3349..4164
                     /locus_tag="VYN42_001434"
     CDS             3349..4164
                     /locus_tag="VYN42_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1462494.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            4171..4575
                     /locus_tag="VYN42_001435"
     CDS             4171..4575
                     /locus_tag="VYN42_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1462495.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            4874..6040
                     /locus_tag="VYN42_001436"
     CDS             4874..6040
                     /locus_tag="VYN42_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1462496.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            6156..7193
                     /locus_tag="VYN42_001437"
     CDS             6156..7193
                     /locus_tag="VYN42_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1462497.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            7400..8254
                     /locus_tag="VYN42_001438"
     CDS             7400..8254
                     /locus_tag="VYN42_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1462498.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEAFAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            8404..8661
                     /locus_tag="VYN42_001439"
     CDS             8404..8661
                     /locus_tag="VYN42_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV1462499.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(8991..9083)
                     /locus_tag="VYN42_001440"
                     /pseudo
     CDS             complement(8991..9083)
                     /locus_tag="VYN42_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9119..9415)
                     /locus_tag="VYN42_001441"
                     /pseudo
     CDS             complement(9119..9415)
                     /locus_tag="VYN42_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(9405..9566)
                     /locus_tag="VYN42_001442"
     CDS             complement(9405..9566)
                     /locus_tag="VYN42_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1462500.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            9636..10400
                     /locus_tag="VYN42_001443"
     CDS             9636..10400
                     /locus_tag="VYN42_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1462501.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLK
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            10965..12344
                     /locus_tag="VYN42_001444"
     CDS             10965..12344
                     /locus_tag="VYN42_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1462502.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            12358..13023
                     /locus_tag="VYN42_001445"
     CDS             12358..13023
                     /locus_tag="VYN42_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1462503.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            13158..13232
                     /locus_tag="VYN42_001446"
                     /pseudo
     CDS             13158..13232
                     /locus_tag="VYN42_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            13378..13917
                     /locus_tag="VYN42_001447"
     CDS             13378..13917
                     /locus_tag="VYN42_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1462504.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQEDKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            13984..14394
                     /locus_tag="VYN42_001448"
     CDS             13984..14394
                     /locus_tag="VYN42_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1462505.1"
                     /translation="MYYLPVDFYRYLIGREGQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            14510..>15738
                     /gene="pavB"
                     /locus_tag="VYN42_001449"
     CDS             14510..>15738
                     /gene="pavB"
                     /locus_tag="VYN42_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1462506.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGEAKNPALSPLGENVKTKGQYFYQVALD
                     GNVAGKEKQALIDQFRA"
BASE COUNT         4406 a         2990 c         3601 g         4741 t
ORIGIN      
        1 gagcgtttga aatgggtcta aaaatgtttg aaactaattg aatgtgtgta taatagtaaa
       61 aatgcagtaa atatcccgac aatttctatt gacaattcaa acagattggt ttattattaa
      121 tataacaaca aatgaaagcg caaactttcg cggtcggaag gtagttttat gacacgattt
      181 gagatacgag atgatttcta tctcgatgga aaatcattta agattttatc tggtgccatt
      241 cattatttta gggttcctcc agaggattgg tatcattcgc tctataactt gaaggctctt
      301 ggttttaata cggtagagac ttatgttgct tggaatttac acgagcctcg tgaaggtgag
      361 tttcattttg aaggtgatct ggatttagag aaatttctcc aaatagcgca ggatttgggt
      421 ctctacgcaa ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt cggtggctta
      481 ccagcttggc tcttgaccaa gaacatgcga attcgctcat ccgacccagc atatatcgag
      541 gcagttggtc gctactatga tcagttattg ccaagactgg tgcctcgttt gttgaacaat
      601 ggtggcaata ttctcatgat gcaggttgaa aatgagtatg gttcttacgg agaagataag
      661 gcttacctga gagcgattcg acagctaatg gaagagtgtg gcgtaacctg tcccctcttt
      721 acatcagatg gtccatggcg agctactctg aaagctggaa ccttaattga agaggacctc
      781 tttgtaacag gaaactttgg ttctaaggca ccttacaact tttcgcagat gcaggaattc
      841 tttgatgaac atggtaagaa atggccactc atgtgtatgg agttctggga tggttggttc
      901 aatcgctgga aagaaccgat tatcacacgg gatcctaagg aattggcaga tgcagttcga
      961 gaggttttgg aacaaggctc tatcaatctt tacatgttcc acggtggtac aaactttggt
     1021 ttcatgaatg gttgctcagc tcgaggaact ttggacctgc cacaagttac atcttatgat
     1081 tacgatgccc ttctggatga agaaggaaat ccaactgcta aatatcttgc agtcaagaag
     1141 atgatggcaa cacatttttc agagtatccg cagttggaac cactctacaa agagagtatg
     1201 gagttggatg ctattccact agttgaaaaa gtttctttgt ttgaaacctt agatagcttg
     1261 tcaagtcctg tagaaagtct ctatcctcaa aagatggagg agctgggaca aagttatggc
     1321 tacctacttt atcgaacaga aacaaactgg gatgcagaag aagaaagact tcgtatcatt
     1381 gatggtcgag atagggccca gctgtatgtc gatggtcagt gggttaaaac tcaatatcag
     1441 acagagattg gggaagatat tttttatcaa ggtaaaaaga aagggctatc taggttagat
     1501 atcttgatag aaaatatggg gcgtgtcaac tatgggcata agttcttagc ggatacgcaa
     1561 cgtaagggaa ttcggacagg ggtctgtaag gatctgcatt tcttactaaa ctggaaacac
     1621 tatccactcc cactagacaa tcctgagaaa attgattttt caaaaggatg gactcaagga
     1681 caaccagcct tttacgctta tgactttaca gtcgaagagc caaaagatac ttacctagac
     1741 ttgtctgagt ttggtaaggg agttgccttt gtcaatgggc agaatctagg acgtttttgg
     1801 aacgttggcc caactctctc actttatatc cctcatagct atctcaagga aggtgccaac
     1861 cgtatcatta tctttgaaac agaaggtcaa tataaagaag agattcattt aactcgtaaa
     1921 cctacactaa aacatataaa gggggaaaac ttatgacaat tgtaggatgc cgtattgatg
     1981 gacgtttgat ccacggacaa gtagccaatc tttgggctgg aaaactaaat gtttcacgca
     2041 ttatggttgt agacgacgaa gttgtcaaca acgatattga aaagagtggt ttgaaacttg
     2101 cgacaccacc aggtgtgaaa ttgagtattt tgccagttga gaaagctgca gccaatattc
     2161 ttgctggtaa atacgatagc caacgtctct ttatcgtggc tcgtaaacca gaccgcttcc
     2221 ttggtttggt agaagcaggt gtaccacttg aaacccttaa tgttgggaat atgtctcaaa
     2281 caccagaaac tcgttctatt acacgttcta tcaacgtagt agacaaggat gtggaagact
     2341 tccacaaact ggcagaaaaa ggtgttaaac ttactgctca gatggttcca aatgatccaa
     2401 tttcagactt tttgagctta ttaaaatagg aaaaaaattt ttaggaggtc attgttatga
     2461 tacaatggtg gcaaatttta cttctcactt tgtactcagc ttatcaaatc tgtgatgagt
     2521 tgacgatcgt ttcatctgca ggttcccctg tatttgctgg tttcattact ggtttaatca
     2581 tgggagatgt gactactggt ttacttatcg gtggtaactt gcaactgttc gttcttgggg
     2641 ttggtacctt cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt cttgcgacag
     2701 ccttctctgt ttcacaagga attgatgcac cgcttgccat tactacaatc gctgtaccag
     2761 tagcagctct cttgacttac ttcgacgttc ttggtcgtat gactactacc ttcttcgctc
     2821 accgtgtgga tgctgcaatc gaacgctttg actataaagg tattgaacgc aactacttgc
     2881 ttggtgcgat tccgtgggct ctatctcgtg cccttccagt cttctttgcc cttgcttttg
     2941 gtggtgcctt tgtacaatca gtagtagact tcgttgaagc ctacaaatgg gttgcagatg
     3001 gcttgacact cgcaggacgt atgcttccag gtcttggatt tgcaatcttg cttcgttacc
     3061 ttccagttaa acgtaacctt cactaccttg ctatgggatt tggtttgaca gctatgttga
     3121 ctgttcttta ctcatatgta acaggtcttg gtggcgctgt tgctggtatc gtaggtactc
     3181 ttcctgctga agttgctcaa aaaattggtt tcgtgaacaa cttcaaaggt ttgtctatga
     3241 ttggtatttc tatcgtaggt attttccttg cagtgcttca cttcaaaaat agccaaaaag
     3301 tagctgtagc agcaccttct acaccatcag aaagtgggga aatcgaagat gacgaattct
     3361 aattacaaac ttacaaaaga agattttaat caaatcaaca aacgtagctt gtttactttc
     3421 caattaggtt ggaactacga acgtatgcaa gcttctggtt acctttacat gatcttacct
     3481 cagttgcgta aaatgtatgg tgatggaact cctgaattga aagaaatgat gaaagttcat
     3541 actcaattct tcaatacttc gccattcttc cataccatta tcgctggttt tgaccttgcc
     3601 atggaagaaa aagatggtgt aggttcaaaa gacgctgtta acggtatcaa gacaggtttg
     3661 atgggaccat tcgctcctct tggggataca atctttggtt cacttgtacc tgctatcatg
     3721 gggtcagtcg cagcaactat ggctatcgct ggccaacctt gggggatctt cctttggatt
     3781 gcagttgcag tagcgtatga catcttccgt tggaaacagt tggaatttgc ttacaaagaa
     3841 ggggttaacc ttatcaacaa catgcaaagt accttgacag ctttgattga cgctgcatct
     3901 gtacttggtg tcttcatgat gggtgctctt gtagcaacag tgattaactt tgaaatttct
     3961 tacaagttgc caatcggtga aaagatgatt gatttccaag acatcttgaa ccaaatcttc
     4021 ccacgtttgc ttccagcaat ctttactgcc tttatcttct ggttgcttgg taaaaaaggt
     4081 atgaactcta ctaaagctat cggtattatt atcgtacttg ctttggctct ttctgccctt
     4141 ggtcactttg cacttggaat gtaattcctt atgactaaat cattaatttt ggtgagccat
     4201 ggtcgcttct gtgaggagct tagaggtagc acagaaatga ttatgggccc acaagacaac
     4261 atttacacag tagctcttct tccagaagat ggcccagaag aatttactgc taaatttgaa
     4321 gctgttattg aagggttgga tgatttccta gtctttgcgg atcttctcgg tgggacacct
     4381 tgtaatgtgg tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta cgcagggatg
     4441 aatcttccaa tggtgattga atttatcaat gcgagcctta caggcgcaga tgcggactac
     4501 aagagccgtg ctgcagaaag tattgtgaaa gttaatgacc tgttagcggg cttcgatgat
     4561 gacgaagatg aataatactc ttcgaaaatc tcttcaaact acgtcaacgt cgccttgccg
     4621 taggtatatg ttactgactt cgtcagtctt atccggcaac ctcaaaacgg tgttttgagc
     4681 tgacttcgtc agtcttatcc ggcaacctca aagcagtgct ttgagcagcc tgcggctagt
     4741 ttcctacaga ttttagttgg aactcgattc aattcatgtg acaacgtgaa aatcgttaga
     4801 gcattttata taaaatatac atgggaatgg agcttactcc cattcccata tttaatagaa
     4861 aaagaggaac tcaatgctac attatacaaa agaagacttg ctcgaattgg gtgcagaaat
     4921 cactacgcgt gaaatctacc aacagcctga tgtatggaga gaagcttttg aattttatca
     4981 agcaaaacgt gaagaaattg cagccttcct acaagaaatc gctgataaac atgactatat
     5041 taaggttatc ttgacaggtg ctgggacttc tgcttatgtg ggagatacct tgctacctta
     5101 ctttaaggaa gtctatgacg aacgcaaatg gaatttcaat gctattgcga caacagatat
     5161 cgttgccaat ccagcaacct atttgaaaaa agatgtggca actgtccttg tgtcttttgc
     5221 tcgtagtggg aactcgcctg aaagtgtggc gactgttgat ttggccaaat ccttggtgga
     5281 tgagctttat caagtgacga ttacttgtgc aacagatggt aaattggctc ttcaagctca
     5341 cggtgatgac cgtaatctct tgctcttgca accagctgtc tctaatgatg ctggatttgc
     5401 catgacttct agctttacgt ctatgatgtt gacagctctc ttggtctttg atcctacaga
     5461 atttgctgtt aagtctgaac gttttgaagt tgtatctagt cttgcccgta aagttttaga
     5521 caaggcagaa gatgtcaaag agctcgttga tttagacttt aaccgtgtca tctatctagg
     5581 cgctggtcct ttctttggac ttgctcatga agctcagctc aagattttgg aattaactgc
     5641 tggtcaagtt gcgaccatgt atgaaagccc agttggcttc cgtcacggtc caaaatctct
     5701 tatcaacgac aatacagttg ttttggtctt tggtacaacg acagactaca ctcgtaagta
     5761 cgacttggac ttggttcgtg aagttgctgg tgaccagatt gctcgtcgtg ttgtgctttt
     5821 gagtgatcaa gcttttggtc ttgaaaatgt caaagaagtg gcccttggtt gtggcggtgt
     5881 cttgaatgat atttaccgtg tcttccctta catcgtttat gcccaactct ttgccctatt
     5941 gacttcactt aaggtagaaa ataaaccaga tacaccgtct cctacaggta cagtaaaccg
     6001 tgtagtacaa ggtgtcataa ttcacgaata tcaaaagtaa gacagtgttt atgaattctt
     6061 gacaagagga tttgtaaatt atcagataaa ccatagattg tcagtacgct ttctatggtt
     6121 tgtttgcttg agagaaatag taaaaggaga acagaatgaa agcatacaca gagcgtgtat
     6181 ttggaaatgt tgagggcgag gatgtcttgg cctatcgatt tgagacagac ggtggctacc
     6241 aacttgaggt tatgacttat ggtgcgacca tcttgcgcta tgtcgcacct gacaaggctg
     6301 gaaattttgc caatgttatc ttgggatttg atgactttga tagttatgta ggcaatagtc
     6361 ccaagcatgg agcaagtgta ggtcctgtag cgggtcgtat tgcaggtgcg acctttgagc
     6421 tcaatggtaa gacctatgac cttgaggtta ataatgctag caactgtaat cacagtggtt
     6481 caactggttg ggattccagc ttgtttgaag ttgaagaagt aagcgatcat ggcttgactc
     6541 tctacacaga gcgtacagat gggacaggag ggttccctgg aaatctcaag atttggatca
     6601 gttatcactt ggaagaaact ggtgcctatg aaatcagcta caaggtgacg accgatcagg
     6661 atacgctggt caatccaacc aaccacagct atttcaactt gtctggtgat ttcacgcaga
     6721 cgattgaccg tcatgtcttc caactaaaca cagagggcat ttactcaatc gctcctgacg
     6781 gtgttcctgc caaaactcca gaagccaacc gtgatgtggt caaacacgtc tacaatggta
     6841 ccttgttgaa ggatatcttt gcagaagaag atgagcaaat ccagctggca tcaggtttgg
     6901 atcatccatt tgcccttcct gcaggccatg acaatgctgg attcctttat gaccaaaatt
     6961 caggtcgctt cctgcttttc aagacagaag ctccttgctt tgtggtctac acagcaaact
     7021 ttgtggatga aagtgtcatc ataggaggtc agccaatgct acagcacaat gggattgctc
     7081 ttgaagcgca agctttacca gatgccattc acagtgacct taaaggccaa gtcattctta
     7141 aagctggtca aaccttcacc agtaagacac gttatgaact tgttgtgaaa taaaaaagct
     7201 ggtcaaaaag tctttaaaat taaaataacg catattgtca ggtgatgaaa agtttgataa
     7261 tatgcgtttt attatgaaat gatttacttt atattatcct gaaatggtgt tatttttgag
     7321 ttatctggct tgactttctt gatggaaatt atataatagt tgtaataata ataattacaa
     7381 cgagaaaaga ggaccattta tgacctatga atacaagagt cacatttatt tggcagagac
     7441 agctttaaat gtaaaggatt tggccagtca aacagccttt tatcagcaag ttattggttt
     7501 agaaatctta tctcaaactg agacagagtc cattctaggc cttggtggaa aagtcttggt
     7561 acagctgatt caagcacaag agagcggaga agtgagggaa cattatggtc tttaccattt
     7621 ggccattctc ttgcccacac gcaaggcttt ggctgatgtc ttgaaacacc tgacagattt
     7681 acagattcct cttgtcggcg gtgcagacca tggttacagt gaagctattt acttggaaga
     7741 tttggaggga aatggcattg aactctatcg agataagcca gtttccacat gggatattcg
     7801 agaagatgga cgcattatcg gagtgacgga ggcttttgcg gcgcaggaca tttatgagtt
     7861 gggggaaaga gtagagccct ttatcctggc agaaggtacg agaatggggc atattcatct
     7921 ttccgtcaag gatagtcgaa agtccagcca gttttatcaa aaggtgttag ggctagagga
     7981 taaattcagt gtgcctagcg ctagttggat tgcggctgga gattaccatc atcatttagc
     8041 agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag caaggcttac caggtttagc
     8101 ctactatgtc atcgaagtcg cacataaaga agaactgtta acgattgtcc aacgagcaca
     8161 agaagttgac gcaccaatca aatggatgac atcgagccaa ttggaaatca cagactcaga
     8221 tggcatcgtg acccgtattc gtttagcaag gtaaaattag gaatttctaa taagttataa
     8281 gtattgctag tttgcttttt gaacggtctt tggtaacaga actgcgtgag ctggatgggt
     8341 gagaattttg acaaagaagc tgattagaga tataatgaag aaaaatcgag caaggaaaaa
     8401 gaaatgacaa attcaaagta tattacttgt ttgaaacgtt cagagggcca gttgtgtggg
     8461 attcaaaaga tgattgaagg agatcgtgac tgtgctgata ttgtgacgca actgacagca
     8521 gtgagatcta gtgtagagcg cgtgattgag atgataatta ccgaaaatct tactgaatgt
     8581 atcaatcagc cactagatga ttctgaagct caaaaggaac gcctagaaaa ggctatccga
     8641 tacttgatta aacggaaata aatgaatgtt ttgagacgat atgtgcaaag gtctattaac
     8701 tattagaata gtttaatgtg agtcaaaaga agttgtaaaa aatctttaaa attaaaaaaa
     8761 cgcatagtat caggtgttga atgtactgac ccccaaaagt tagatttttt ctgtctaact
     8821 tttgggggtc agttcataag aaccttggta atatgcgttt tattatgtag agacttatac
     8881 tcttcgaaaa tctcttcaaa ccacatcagc ttcaccttgc cgtagatatg gttactgact
     8941 tcgtcagttc tatccacaac ctcaaaacag tgttttgagc tgacttcgtc agttccatcc
     9001 acaaccttaa aacagtgttt tgagcagcct gcggctaact tcctagtttg cactttaatt
     9061 ttcattgagt attacttcat cttctcatga aattgagttt ttgcccagct cctcttgatt
     9121 attctacttg accgggccaa gtattcatac caccttctac gttggtaacg gtgaggcctt
     9181 gggagctgag aaattggcag gtagatgcag agcggactcc tccttgacaa ataacatagt
     9241 attcatggtc aggtttgagt tctttgtagc cttgctctaa ggtacttaat ggaagatttt
     9301 tggcacctgg tgcatgtcct gcttggaatt catgtgcttc acggacatcg ataagttcta
     9361 gattttcatt ttagtatttt ccataaaagt cagccatgct gatactagtt tccatattct
     9421 actccttctg ggttagccat tttgtatagt gaataagcgc cgtcaaggtt ttggacggta
     9481 aatcctgctt gcttgaggat aggctctgcg atatagctgc gcaaaccact gtggcagctg
     9541 acgatgtagg cttgtttttt gtccagttca tcagcttcct ccttgacact ttgtcagttt
     9601 ttgatacaat agtacaaaat tagaggaggc aggctatgat tcagaaacat gcgattccta
     9661 ttttagagtt tgatgacaat cctcaggcgg ttatcatgcc caatcacgag gggctggact
     9721 tgcagttgcc aaagaagtgt gtttatgcat ttttaggtga ggagattgac cgctatgcaa
     9781 gggaagtagg ggcggattgt gtcggcgaat tcgtttctgc taccaagacc tatccagtct
     9841 atgtcatcaa ctacaagggt gaggaagtct gtctggctca ggctcctgtt ggctccgctc
     9901 cagcagccca gtttatggat tggttgattg gctatggtgt ggagcagatt atctctactg
     9961 ggacctgtgg tgtcctagct gatatagagg aaaatgcctt tctagtccct gttcgcgctt
    10021 tgcgagatga gggagccagt taccactatg tggcaccttg tcgttatatg gaaatgcagc
    10081 cagaggctat tgctgctatt gaggaagttt tgaaagacag agggattcct tatgaagaag
    10141 tcatgacctg gacgacagac ggtttttacc gagaaacggc tgaaaaggtg gcttatcgta
    10201 aggaagaagg ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca gtagctcaat
    10261 tgcgtggggt tctctggggt gaattgttgt tcacagcaga ttctctagcg gacttggacc
    10321 agtacgacag tcgtgactgg ggctcggaag cttttaataa ggcgctagaa ctgagtttag
    10381 caagtgttca ccacctttag ttgtacaggc aaaggatttg ttttatcata aaatgtctag
    10441 ctcatacttt tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct aggcatgttg
    10501 aggttgggaa aaatctttaa aatcagaaaa acgtatcata tcaggtgatg aaaattttga
    10561 tactatgcgt tttatgttgg taagatttag agtgagatga aatgatactc ttcgaaaatc
    10621 tcttcaaacc aggtcagctt caccttgccg tatagatgtt actgacttcg tcagttctat
    10681 ctgcaacctc aaaacagtgt tttgagcaac ctgtgactag ctttctaagc gatgccttgg
    10741 ttctcattgc ctataatcaa aaagagaaat tttctcctga aaagcatata gagtagctgg
    10801 cgttaaaagc tcctgtcttg cttttttgac ctatagtcac atctatcaag tattgttctt
    10861 gcctaagcta tcaataaaaa ggtggcattt tttaggcttg gtgttagtga attttgcctt
    10921 atcctatcta agtcatttcg agctttttat ggtacaatgg aaacatgtta ttcaaattat
    10981 ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc agcccgtcgt atttttttga
    11041 gttttgcctt ggtcatttta ctaggctctc ttcttttgag cttgcccttt gtccaagttg
    11101 aaagctcacg agcgacttat tttgatcatc ttttcactgc tgtctctgca gtctgtgtga
    11161 caggtctctc aacccttcca gtagctcaca cctataatat ctggggccaa ataatctgtt
    11221 tgctcttgat tcagatcggt ggtctagggc tcatgacttt tattggggtt ttctatatcc
    11281 agagcaagca aaagcttagt cttcgtagcc gtgcaactat tcaggatagt tttagttatg
    11341 gagaaactcg atctttgaga aagtttgtct attctatttt tctcacgacc tttttggttg
    11401 agagcttggg agctattttg cttagttttc gccttattcc tcaacttggc tggggacgtg
    11461 gtctttttag ttccattttt ctagcgatct cagccttctg taatgccggt tttgataatt
    11521 tagggagcac cagtttattt gcttttcaga ccgatttact ggtcaatctg gtgattgcag
    11581 gcttgattat tacaggcggc cttggtttta tggtctggtt tgatttggct ggtcatgtag
    11641 gaagaaagaa aaaaggacgt ctgcactttc atacgaagct tgtactatta ttgactatag
    11701 gtttgttgtt atttggaaca gcaactactc tctttcttga gtggaacaat gctggaacga
    11761 ttggcaatct ccctgttgcc gataaggttt tagttagctt ttttcaaaca gtgacgatgc
    11821 gaacagctgg cttttctacg atagattata ctcaggctca tcctgtgact cttttgattt
    11881 atatcttaca gatgtttcta ggtggggcac ctggaggaac agctggggga ctcaagatta
    11941 cgacattttt tgtcctcttg gtctttgcac gaagtgagct tctaggcttg cctcatgcca
    12001 atgttgcgag acgaacgatc gcgccgcgaa cggttcaaaa atcctttagt gtctttatta
    12061 tctttttgat gagcttcttg ataggattga ttctgctagg gataacagcc aaaggcaatc
    12121 ctccctttat ccacctcgta tttgaaacca tttcagctct tagtacagtt ggtgtaacgg
    12181 caaatctgac tcctgacctt gggaaattgg ctctcagtgt tatcatgcca cttatgttta
    12241 tgggacgaat tggtcccttg accttgtttg ttagcttggc agattaccat ccagaaaaga
    12301 aagatatgat tcactatatg aaagcagata ttagtattgg ttaagaaagg aaagagcatg
    12361 tcagatcgta cgattggaat tttgggcttg ggaatttttg ggagcagtgt cctagctgcc
    12421 ctagccaagc aggatatgaa tattatcgct attgatgacc acgcagagcg catcaatcag
    12481 tttgagccag ttttggcgcg tggagtgatt ggtgacatca cagatgaaga attattgaga
    12541 tcagcaggga ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa tctggagtcg
    12601 agtgtgcttg cggttatgca ctgtaagagt ttgggggtac cgactgttat tgctaaggtc
    12661 aaaagtcaga ccgctaagaa agtgctagaa aagattggag ctgactcggt tatctcgcca
    12721 gagtatgaaa tggggcagtc tctagcacag accattcttt tccataatag tgttgatgtc
    12781 tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc ttgggcaggt
    12841 caaagtctga gtaaattaga cctccgtggc aaatacaatc tgaatatttt gggtttccga
    12901 gagcaggaaa attccccatt ggatgttgaa tttggaccag atgacctctt gaaagcagat
    12961 acctatattt tggcagtcat caacaaccag tatttggata ccctagtagc attgaattcg
    13021 taaagaggga tgacccctct tttttgatgc ccaagatggc aaatagagac agaagcccct
    13081 tgtcttctag taaaagttct tcaaaggctg gactttatgg taaaatagaa agaagtgaca
    13141 agagagagta atactcaatg aaaatcaaag atcaaactag gaaactagct acgggctgct
    13201 caaaacagtg ttttgaagtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg
    13261 aggttgcaga tagaactgac gaagtcagta acatctatac ggcaaggcga cgttgacgcg
    13321 gtttgaagag attttcgaag agtataagaa aaaatcagtc ccctaaagga gcagattatg
    13381 aagttattgt ctatcgcaat ttctagctat aatgcagcag cctatcttca ttactgtgtg
    13441 gagtcgctag tgattggtgg tgagcaagtt gggattttga ttatcaatga cgggtctcag
    13501 gatcagactc aggaaatcgc tgagtgttta gctagcaagt atcctaatat cgttagagcc
    13561 atctatcagg aagataaagg ccatggcggt gcggtcaatc gtggcttggc agaggcttct
    13621 gggcgctatt ttaaagtagt tgacagtgat gactgggtgg atcctcgtgc ctacttgaaa
    13681 attcttgaaa ccttgcagga atttgagagc aagggtcaag aggtggatgt ctttgtgacc
    13741 aattttgtct atgaaaagga aggtcagtct tgtaagaaga gtatgagtta cgattcagtc
    13801 ttgcctgttc ggcagatttt tggctgggac caggtcggaa atttctccaa aggccagtat
    13861 atcatgatgc actcgctgat ttatcggaca gatttgttgc gtgctagcca gttctaattg
    13921 cctgaacata ctttttatgt cgataatctc tttgtcttta cgccccttca gcaggtcaag
    13981 accatgtact atctgcctgt cgatttctat cgttatttga ttgggcgtga gggccagtct
    14041 gtcaatgagc aagtgatgat taagtgcatt gaccagcaac tcaaggtcaa tcgactcttg
    14101 gtagaccagc ttgatttgtc ccaagtgagt catcctaaaa tgcgagaata tctgctgaat
    14161 catattgaaa tcacgacggt gatttccagt accctgctca accgatctga aacagcggag
    14221 catctggcaa aaaaacgcca attgtggacc tatattcagc aggaaaatcc aaaagtcttt
    14281 caggctattc gtaagaccat gttgagccgt ttgaccaaac attctgtctt gccagatcgc
    14341 aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt atggatttaa ttaatataag
    14401 tgttttataa gagggattta agaaaaattt taactttttc ttagtccttt ttaatttcag
    14461 gagattatac tagagtcatc aaataaagaa agactctaag gagaatccta tgaaattcaa
    14521 tccaaatcaa agatatactc gttggtctat tcgccgtctc agtgtcggtg ttgcctcagt
    14581 tgttgtggct agtggcttct ttgtcctagt tggtcagcca agttctgtac gtgccgatgt
    14641 ggtcaatccg accccaggtc aagtcttacc tgaagagaca tcgggaacga aagagggtga
    14701 cttatcagaa aaaccaggag acaccgttct cactcaagcg aaacctgagg gcgttactgg
    14761 aaatacgaat tcacttccga cacctacaga aagaactgaa gtgagcgagg aaacaaactc
    14821 ttctagtctg gatacacttt ttgaaaaaga tgaagaagct caagaaaatc cagagctaac
    14881 agatgcctta aaagaaactg tagatacagc tgatgtggat gggacacaag caagtccagc
    14941 agaaactact cctgaacaag taaaaggtgg agtgaaagaa aatacaaaag acagcatcga
    15001 tgttcctgct gcctatcttg aaaaagctga agggaaaggt cctttcactg ccggtgtaaa
    15061 ccaagtaatt ccttatgaac tattcgctgg tgatggtatg ttaactcgtc tattactaaa
    15121 agcttcggat aatgctcctt ggtctgacaa tggtactgct aaaaatcctg ctttacctcc
    15181 tcttgaagga ttaacaaaag ggaaatactt ctatgaagta gacttaaatg gcaatactgt
    15241 tggtaaacaa ggtcaagctt taattgatca acttcgcgct aatggtactc aaacttataa
    15301 agctactgtt aaagtttacg gaaataaaga cggtaaagct gacttgacta atctagttgc
    15361 tactaaaaat gtagacatca acatcaatgg attagttgct aaagaaactg tcgaaaaagc
    15421 tgttaaagat aacgttaaag acagtatcga tgttccagca gcctacctag aaaaggccaa
    15481 gggtgaaggt ccattcacag caggtgtcaa ccatgtgatt ccatacgaac tcttcgcagg
    15541 tgatggcatg ttgactcgtc tcttgctcaa ggcatctgac aaggcaccat ggtcagataa
    15601 cggtgaggct aaaaacccag ccctatctcc actaggcgaa aacgtgaaga ccaaaggtca
    15661 atacttctat caagtagcct tggacggaaa tgtagctggc aaagaaaaac aagcgctcat
    15721 tgaccagttc cgagcaaa
//
LOCUS       DAVLUM010000049        14662 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLUM010000049 DAVLUM010000000
VERSION     DAVLUM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.049"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            53..1114
                     /gene="dinB"
                     /locus_tag="VYN42_001450"
     CDS             53..1114
                     /gene="dinB"
                     /locus_tag="VYN42_001450"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1462507.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(1261..2106)
                     /locus_tag="VYN42_001451"
     CDS             complement(1261..2106)
                     /locus_tag="VYN42_001451"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1462508.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLVV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(2137..2274)
                     /locus_tag="VYN42_001452"
     CDS             complement(2137..2274)
                     /locus_tag="VYN42_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462509.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            2361..3379
                     /locus_tag="VYN42_001453"
                     /pseudo
     CDS             2361..3379
                     /locus_tag="VYN42_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(3680..5569)
                     /locus_tag="VYN42_001454"
     CDS             complement(3680..5569)
                     /locus_tag="VYN42_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1462510.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLLAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            5707..7272
                     /locus_tag="VYN42_001455"
     CDS             5707..7272
                     /locus_tag="VYN42_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1462511.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAIKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYISEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAAHALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            7272..8012
                     /locus_tag="VYN42_001456"
     CDS             7272..8012
                     /locus_tag="VYN42_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1462512.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(8121..8336)
                     /locus_tag="VYN42_001457"
     CDS             complement(8121..8336)
                     /locus_tag="VYN42_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462513.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(9207..10457)
                     /gene="ilvA"
                     /locus_tag="VYN42_001458"
     CDS             complement(9207..10457)
                     /gene="ilvA"
                     /locus_tag="VYN42_001458"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1462514.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(10507..10647)
                     /locus_tag="VYN42_001459"
                     /pseudo
     CDS             complement(10507..10647)
                     /locus_tag="VYN42_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
     gene            complement(10832..11068)
                     /locus_tag="VYN42_001460"
     CDS             complement(10832..11068)
                     /locus_tag="VYN42_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462515.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(11175..12197)
                     /gene="ilvC"
                     /locus_tag="VYN42_001461"
     CDS             complement(11175..12197)
                     /gene="ilvC"
                     /locus_tag="VYN42_001461"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1462516.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(12263..12739)
                     /gene="ilvN"
                     /locus_tag="VYN42_001462"
     CDS             complement(12263..12739)
                     /gene="ilvN"
                     /locus_tag="VYN42_001462"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1462517.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(12732..14432)
                     /locus_tag="VYN42_001463"
     CDS             complement(12732..14432)
                     /locus_tag="VYN42_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1462518.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGADTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
BASE COUNT         4517 a         3258 c         2603 g         4284 t
ORIGIN      
        1 agagctgacg tggtttgaag agattttcga agagtataaa aaggtgctag gcatgttgat
       61 ttttcctttg ttaaatgatt tgtcaagaaa aatcatccat attgacatgg atgccttttt
      121 tgctgcagtg gaaatcaggg ataatcctaa actcagagga aaacctgtca ttattggaag
      181 cgaccctcgg caaacaggtg gacggggagt cgtttctacc tgtagttatg aggcaagagc
      241 ttttggtgtc cattctgcca tgagttccaa ggaagcttat gaacgttgtc cccaggctgt
      301 ctttatctca gggaattatg agaaatacaa gtctgtggga ctccagattc gagctatttt
      361 taagcgctat acagatttga ttgaacccat gagcattgac gaagcctatt tggatgtgac
      421 agaaaataaa ctcggtatca agtcagcggt caaaattgct cgcctcattc aaaaagatat
      481 ctggcaagaa ctccatctaa ctgcttccgc aggcgtttct tacaacaaat tcttagctaa
      541 aatggcgagt gattatcaaa aaccacatgg tttgacagtg attctacctg aacaggctga
      601 ggattttctc aaacaaatgg atatttccaa atttcatgga gtaggaaaaa agacagtaga
      661 acgtcttcat caaatgggcg tttttactgg tgctgattta cttgaagttc ctgaggtaac
      721 cctaatagac cgttttggta gactaggcta tgatctgtat cgaaaggctc gtggcattca
      781 caactctcca gtcaaatcca atcgcatccg taaatcaatc ggcaaggaga aaacctacgg
      841 gaagattctc cttgctgagg aagatatcaa aaaagagctg actcttctat cagaaaaagt
      901 cgctctcaat ctacatcaac aagaaaaagc tggaaaaatt gtcattttga aaatccgcta
      961 cgaggacttt tcaactctta ccaaacgaaa aagtcttgct caaaaaacac aagatgctag
     1021 tcagataagc caaatagccc tgcaactcta tgaagaatta agcaagaaag aaagaggtgt
     1081 ccgcctattg gggattacca tgactggatt ttaaagctca atgaaaatca aagagcaaac
     1141 taggaggcta gccgcaggct gctcaaaaca ctgttttgag gttgcagata aagctgacgc
     1201 ggtttgaaga gattttcgaa gagtataaaa ccttgaagag ttgccccttc aaggtttttc
     1261 ttatacaaat aaacggacaa aactgtaaag tagcaaaaca ctaccaagca cgatacggta
     1321 tttaccaaaa agggtgaagt cgtgtttttt cacatagctg gtcaagaagc gaatagccac
     1381 catgctgacc gcaaaagcta ctcccatcgc gaccaagagc aaaaacaatt gcccaaagct
     1441 caagagttct ccggctttca caaatttgaa aatctttaag gcactagctc caaacataac
     1501 aggaatccca agatagaagg taaattctgt cacaactgaa cgactggttc catttaacaa
     1561 accaccgaca atcgttgcac ctgaacggct agtccctggt aaaagagcaa gaacttggaa
     1621 gagtccgata tagaaagcgg tcgtataagg aagcttgtcc aactctgtta cacttggctc
     1681 gatagcacgc gctttattgc gcttttccaa atagatgaag gcaaccccgt agataatcaa
     1741 catgagagca actgaaacca tgttatggaa gtgggtatca aaccaatcat caaatttaaa
     1801 gacaacaagt aaaggtaaag tagcaatcaa gaccttcaac catagtctcc aagtcttacg
     1861 aacttcctgt ttgtccttgg tcggtttaaa aggattgagc ttgttaaaat aaatcaccat
     1921 aactgctaaa atagcaccaa gctgaatcac gacattaaac atggacataa aggcttcatt
     1981 ttgattttgg tattggatga attcctctgc taaaatcaag tgacctgtac tggaaatcgg
     2041 caaccattcc gtaattcctt caacaattcc gaagaagata gattttaaaa tttcaataag
     2101 atacatagat tactccctat attatattta gcgcagttag ctactgccaa agcccaagtg
     2161 gtatacttgg aataagccac tatggattag ttcatttcct ccaatcgctt gacgatttcc
     2221 gaaaggctct aaccacagct tttgtttcaa ttggtaatga gtttgataac gcatagacgt
     2281 ttgatctcgt ctaaggtaac aaggcaaaaa attcgtggat aaccaagtag acttgaaata
     2341 ctatatctgg aggtactccc atgctttatg taggcattga tatcgctaaa aataaacacg
     2401 atgttacagc cttgaatgtt ccaggaaaaa ctgttcttaa accactcact ttttcaaata
     2461 ataaagctgg ttttgaactc ttagatctgt ctattcgaca gatcaaccaa gactgtctca
     2521 tcgctcttga agatactgga cattatgcct ttaatctact gaacttcctg catgaacaag
     2581 gatataaagt ttacacctac aatcctttgc tcatcaagga atttgccaaa tcattatcac
     2641 ttcgcaagac taaaacggat aagaaagacg ctcatggcat cgctcttaaa cttctttctg
     2701 accccaatcg tgaacaattt caacacgata atcggcaagt agacctaaaa atactggcta
     2761 gacatattca tcgtctcaag aaaaacagtc tgattggaaa gtacaataca ctcgttgtct
     2821 tgatatcatc tttcctgagt tggataaaat cgttggaaag cattcagaat atacctacca
     2881 actcttgaca cgctacccta atcctcagaa aaggattgag gcaggatttg ataagctgat
     2941 agaaattaag cgattgaccg cttctaaaat tcaggatatc ctctcagtcg cacctcgttc
     3001 tatcggaaca acatctcctg ctcgtgaatt cgaaatcatc aaacattaca agaggctcat
     3061 tgacaaggcg gaaacatgtg tcaatgactt gatggctgag ttcaactcgg tcatcacgac
     3121 ggtcactggg attgggaatc gtttaggggc ggtcatttta gccgagattc gaaatattca
     3181 tgcctttgat aatcctgctc aattacaagc tttcgctgga ctggattctt ctatttatca
     3241 gtcaggtcag attgatttag ctggaagaat gatcaaacgg ggttcccctc atctgcggtg
     3301 ggcactcata caagctgcca aagcatgcgc tcgcttttca cctgctttta aggcctatct
     3361 taagactaag ttagaataag gaaaacatta caatgtagcc atcatccacc ttgcaaaaaa
     3421 acttatccga accctgtttt atatcctaaa aaagagctgc catttgacga acaaaaagtg
     3481 atgtaatttc tgaaattaac acaggattac ctttgaaaaa atggactttt tcaagggctt
     3541 tttgccgtgc tctaaaatca tcgccaaatc atcaaattga aataagaaat agtttagata
     3601 aaactattga cttttcttat agtttgtctt tcttctatct tccattatat catacttttt
     3661 cagtctatgg tagctctctt taaaaggctc cgatactgcc gccacctccg cctccagaga
     3721 agccaccgcc agaacttcca cttccagaag atacggagta ggtacttgct gtatttgcga
     3781 cactagcata atggctcatt tgcgcgcttg aatgataaaa catactgtgc cagccataag
     3841 ctacatagag attgatatct ggattttcaa cttgaatctg atgaaccttc atcaaatgac
     3901 taaccttgtc cgcatagcca aataaggttg catagaccaa gagacgattc caaacaacaa
     3961 tactttccaa ttcagcctta tccagtcgtg caatctcacg taacatattt tcaaaactgg
     4021 tccagagata gtagacctca gctcccgctt catttagaac accatcacga ttatctagtc
     4081 gaagcttcca ataatagaaa acagacaaaa ctaaccctag aaaaccaagt attggcaaag
     4141 ggaggtaaag atagccatga acgtctaaac tgtacaagaa caaaccaaat ccgataaata
     4201 ggggcaagat agtcaagaca cccataccca cttgcaaagc cttttccaaa ccagttaaag
     4261 gacgatagta atctgggagc ccccagaagg aaactcgttt tctcactcct tcttgcatct
     4321 ggttcaatac ctcttcaaaa gaagatttga gttgaagccc tcttgcttga atccgttttt
     4381 catcagaaac tttggctcta cgataaagac tatcagatac cttgtaatcc gcaaacaaat
     4441 tggaaagagt ttcttctttt ttacctgaaa aagctagatt taggcagtct ttctcaaagc
     4501 ttgacaaacc atcttctttt actagcctca aaccaactgc atctccttct gaaatgatag
     4561 agacattccc acggtctatc acatctagca aggtagcttg aataagttga tcaaaggtga
     4621 attttccagc tcccttgacc aagggactca cttcctccaa ggaggtcgag tagactgctt
     4681 ctgataaaac cataggctct aattccattg ggggttcata gagacgatga tttttagcat
     4741 atttgattga aggagcggtc tttcttctat agataaaata gaaacagatg ctcaataaca
     4801 aggagatgga aaggatcgaa gggaagatcc aagtaagtag ttgtttactt tgctcttttt
     4861 ctttaacgat cgaatcctct atcttattaa actcttctaa acgattccct ttcaagccct
     4921 gatccctagc gctagcaaaa tcagttcgcg gccagtaggc atgcaattca actccacgct
     4981 tagccagaag attgtctaaa cgaatagtat aatcaaggtt actcttttca accgttctct
     5041 ctctaaaaag tttccctgta tggaaaaaga gtttctcagc ccccttgtct ccccttacat
     5101 gaaattcaaa cttttcaata gactctgaac tatctgtcag aggttgccaa tttaattcag
     5161 cgatatcatc ataaaggaaa agtaaatttt ttaagttcca aacgaggtca acttcaacta
     5221 tgtcgccctc ctgacctgga ttatagactc tcacagtata accatccgct tcttctgtta
     5281 cttcgctagt cacatctgct agttctgcac cgtttttcgc ggcctgaatc tttggatgag
     5341 ggtcaatgtc aaacccgcta ggcatcttac cagcacgtcc aagtcccacg atttggccct
     5401 taaagtcctc ctcaaactgg taaactatct tctgtctaaa ctctgccgta ttgtctgcat
     5461 gaatatacaa atccccttga taagagttta tcttgaaatc aatggcaaaa acagagagtg
     5521 gaagaaggca aaacaagcct aacaccagta agaaaaaagt ttttttcatc aactaagccc
     5581 cctttttatc tttcttatca ttatagcatt ttttcgtaag taaagactta cttatgttga
     5641 aaaattacgc atttttcgat aaaataggag acagttattt tttaatagat cagaatagga
     5701 gaaatcatga gaaaaatata cttatctatt ttcacaagtc tcttgctgat gctaggactt
     5761 gtcaatgttg ctcaagccga tgaatattta cgcatcggga tggaagcagc atatgctccc
     5821 tttaactgga cccaggatga tgatagcaac ggagctatca aaatcgatgg gaccaatcag
     5881 tatgccaacg gatacgatgt tcaaatcgcc aagaaaatcg ctaaggactt aggtaaagaa
     5941 cctttggttg ttaaaaccaa gtgggaaggt ctagtccctg cccttacttc tggtaagatt
     6001 gacatgatta tcgcaggtat gagtccaact gcagaacgca aacaagaaat tgccttttcg
     6061 agcagttact acattagcga accagttcta ctggtcaaaa aagattctgc ctatgcaagt
     6121 gctaaatctt tggatgactt taatggtgcg aaaatcactt ctcaacaagg ggtctacctt
     6181 tatgacttga ttgcacaaat cacaggtgct aaaaaagaaa cagccatggg agacttcgct
     6241 caaatgcgcc aagctcttga ggctggtgtc atcgacgcct atgtttctga acgcccagaa
     6301 gctctgactg ccgaagccgc taactctaag ttcaagatgg tccaagtaga accaggtttc
     6361 aaaactgggg aagaagatac agctatcgcc attggacttc gtaaagatga cactcgtatt
     6421 agccaaatca atgccagcat tgaaaccatt tcaaaggacg accaagttgc cctgatggat
     6481 cgtatgatca aggaacaacc tgccgaagct acaacaactg aagagactag cagtagtttc
     6541 tttagccaag ttgctaaaat tctttctgaa aactggcaac aactcttgcg tggtgctggt
     6601 atcactcttt taatctctat cgtcggaacc atcacaggtc tcattattgg acttgccatt
     6661 ggtgttttcc gtactgctcc tctctctgaa aacaaagtca tttacagcct acaaaaacta
     6721 gtcggctgga tcctcaacgt ctacattgaa attttccgtg gtacgccaat gattgttcaa
     6781 tcgatggtta tctactatgg aactgcccaa gctttcggta tcaaccttga ccgtacactg
     6841 gctgctatct tcatcgtttc aatcaatacc ggtgcctaca tgactgaaat cgtccgtggt
     6901 ggtatcctag cagttgacaa gggacaattt gaagctgcgc atgctcttgg tatgacccat
     6961 aaccagacca tgcgtaagat tgtcctacct caggtagtcc gtaacatcct acctgcaact
     7021 ggtaatgaat ttgtcatcaa tatcaaagat acatctgtat tgaacgttat ctctgttgtc
     7081 gaactttatt tctcaggaaa taccgtggca acacaaacct atcaatactt ccagacattt
     7141 acaatcatcg ccgtgattta ctttgtcctc accttcaccg taacacgtat cctacgattt
     7201 atcgagcgcc gaatggacat ggatacctat actacaggtg ctaaccaaat gcaaacggag
     7261 gatttgaaat aatgacacaa gcaatccttg aaattaaaca cctcaaaaaa tcctatggac
     7321 aaaacgaagt gctaaaagac atttcactca ctgtccacaa gggagaggtc atctctatca
     7381 tcggaagctc tggaagcgga aaatcgacct tcctacgctc cattaaccta cttgaaacac
     7441 caactgatgg acaaatcctt tatcatggac aaaacgtcct cgaaaaaggc tatgacctca
     7501 cgcaataccg tgaaaagttg gggatggttt tccaatcctt taacctcttt gaaaatctca
     7561 atgttcttga aaacacaatc gtcgctcaga caactgtcct aaaacgcgaa cgcacagaag
     7621 ctgaaaagat tgccaaagaa aacctggaaa aggtcggcat gggagaacgc tactggcaag
     7681 ccaaaccaaa acaactctca ggtggtcaaa aacaacgtgt ggccatcgct cgtgccctct
     7741 ccatgaatcc ggacgctatt ctctttgatg aaccaacatc agctctcgat ccagaaatgg
     7801 ttggagaagt cctcaaaatc atgcaggacc tagctcagga aggcttgacc atgattgtcg
     7861 taacccatga aatggaattt gcccgtgatg tctctcaccg tgttatcttt atggataagg
     7921 gcgtgatcgc tgaagaaggt aaaccagaag acctcttcac caatcctaaa gaagaccgaa
     7981 caaaagagtt ccttcaacgc tatctcaaat aaaaagaaaa ggctgcatca accgtgcagt
     8041 ctttttgctg tcctcaaaat aaaaaggcag attctctatc tctactactt gaaggtcaag
     8101 aatccgccgt tatccaaaga ttaatcttca aatttttcat aatttttttc atagaaatca
     8161 attaggccta gggctgtttc aaatgaaata ttttttactt ttgcacgacc ctgcgccaga
     8221 gcaatgatag acatttcacg cgcattcgtt tctttagaga tacggtagcc tgtgattttc
     8281 ttatcacgaa cccagccaac aactgattct actttttcaa agtttgactt agccatgttt
     8341 ttctcctatt ttcttcttta taatatttaa ttgtatacgt ttttactact tttgtcaata
     8401 aaaaaaacat atattcaacg aaaataatta gttcagaatt ttcttacttc ctttttaaat
     8461 ccaataatat ataggttttg ctagcctcta caccataaat atttgctaat aaaaatactg
     8521 tattattacc ctcttaaggt gcgaaattat tcaagttctt aaaaaatgct tctctatttc
     8581 cgtaagatag cttatttctt cgatttaaga actgaagatg atagttctaa cctttagaaa
     8641 tccaagcctt cactagctca aaaactccta tctttcttcc tcaataaatc atctgagaga
     8701 taggtattcc ttatatcttt caaattcatc actcctttgg atattgaggt gctagcctag
     8761 aagcagacac ccgattatct aaaccatcct taatagagat gacaagacag ataagctcag
     8821 ttaattactt atatatcttt ttaatatggt atatttgtca acaaaaagaa atcaaatcat
     8881 accttatact caatgaaaat caaagagcaa actaggaagc tagccgcaag ttgctcaaaa
     8941 cactgttttg aggttgcaga tagagctaac gtggtttgaa gagattttcg aagagtatta
     9001 aagacagtgt gactatgctt gtcaatagat aggaaatcaa aatgaaggat ggaaatctga
     9061 gccaaacatc ataagtgcta taatgaacag aagtaagaat tgcacgataa gttttctaaa
     9121 accataggaa tcgtcccctt tcttcatctt cattatagca catatacatc agttgtacaa
     9181 ataatatgat atttttttat tagtcctcag acaagcatat tataaagcgt ttcattacca
     9241 tttaagttaa tataagctgg atcaaaacct tccattctac ggatcaaacc tgcataatca
     9301 tgcttatctg ctaaagcgat cccaatcaat actgggcctg ttcccttgct agctcgtttg
     9361 atatactcaa aacgtgtgat atcatcattt ggccccagga tatcatttac aaactcacgc
     9421 aaagctcctg gacgttgtgg gaaattgacc acaaagtaat gtttgatacc atcataaatc
     9481 aaggcacgct cttccatttc tggcatacgg ttgatatcat tatttcctcc agaaatgata
     9541 caacaaatgg ttttcccctt aatatattca gctaaaacct ctaaagaggc gatactagcc
     9601 gctccagcag gctctgcgac tatcccttgc ttagagtaaa ggtcaatcaa ggtttcagaa
     9661 atcaatccct catcgacacc taccaaagtt tgaatatgtt gacgagttgc ttcataggtc
     9721 aactgaccta ccttttgcac agcaatccca tccgcaaatt tatcaatttc cttgagtttg
     9781 actggacctc cagcctcaaa ggcagctttc atggaacgcg ctccattcgc ctctactccg
     9841 ataacctcaa tctctggact tgtttccttg atataggtag aaaccccggc aatgagaccg
     9901 ccaccaccaa caggaaccaa gacagcatca aaatcaatcg attcttttcg agcttcttct
     9961 aaaatctcat aagcaactgt tccttgacct gcttgaacat gagcatcatc aaaaggatca
    10021 ataaaggtac gattttcaga gactgtaaat tcttgagctg ctttggctga ggcatcaaag
    10081 gtatctccaa ctagtttaat agttacaaaa tccccaccaa aaaagcgaac ctgaccaatc
    10141 ttttgttgtg gcgtagtaat gggcataaag atagtagcag gaattttcat ttcattacaa
    10201 gtataggcta ctccctgcgc atgatttccc gcagaagcgc agactacccc acgttcacgt
    10261 tcttccttgc tgagctggga aatggcataa taggcaccac gaattttaaa ggagcgaaca
    10321 cgctgggcat tttctttttt caaataaatc ttagcaccat acttctccga taaataatga
    10381 tcgtaatcca gtggagtatt cacaaccaca ccgttcaaga ccttgtgagc cttgattata
    10441 tcttttgaac ttaacatata aaacctcttt ttctataaaa aacagtcact aatgactgtt
    10501 ttttagttat tcatctccga aaacttcagt aacactttca tggtatttat gagccatacg
    10561 aatcgaaaac tctttaggaa gttcataacg atttgtggaa atccaatcat ataaccattc
    10621 taccaaactt tcttcactat cattacgaaa gttttcgcag tccagtcatt taaacccgat
    10681 tctttcaatc cagatgcaat aatttgctct atttgatata aaccgccatc tatcgtctca
    10741 tttattctgc gaagaggacc ttcaatatag gataaagctt ctccgaatct aacagctgat
    10801 ttaggtccta atgatttacc aactatattt gttaatgttt tttatttctc aaaatccatt
    10861 tcgctatata acgagcagat ttagtcgcac cagctctctc aaacggagaa tgaatttcaa
    10921 gaccttcttc tctagctatt tgtgccaatt tgaagaattg ttcaaaggtc atatgcaacc
    10981 taccatcttc aaaattagca tcatcataaa tgttaattac agcattttca tcatacgacc
    11041 aatctgcttt attttggtct gctagcacta ttaccgacgg tgtaattaca ttatacaact
    11101 agaaccaata ataacgatgc aatttttctc ataatctttt tcataaaatc atctccagcg
    11161 ctatatattt ctaattagtt atagattttg aatgcatcat cgtcgttttt accaacgaat
    11221 ggcattgctt tacgcaattc tgcaccaact ttttcaattt caaggttagc tgcttgttca
    11281 cggtaagcag tcaattttgg acgtccagct ttatagtcat ttacaaagtc atttgcaaat
    11341 ttaccatttt ggatgtctgc caagacagcc ttcatatttt ctttaacttg ttcagtgatt
    11401 acacgtggac ctgatacata gtcaccgtat tcagcagtgt ttgaaataga ttgacgcatt
    11461 ttcttgaatc caccttcgta gatcaagtca acgatcaatt tcatttcgtg aagaacttca
    11521 aagtaagcca attctggagc gtaacctgct tctgtcaaga cttcgaaacc tgcttcgata
    11581 agggcagtca aaccaccaca aagtacagct tgttcaccaa acaaatcttc ttcagtttct
    11641 tctttgtaag ttgtttcaag aagacctaca cgagccgctc caacaccttt acaccagtcc
    11701 atagcaatgt ttttagcatt tcctgttgca tcttggtata ctgcataaag agctggaaca
    11761 ccaaatcctt cttcgtaagt acgacgtacc aagtgtcctg gtcctttagg agcacacatg
    11821 aagacatcta catccgcagg aactttgata aattcaaagt ggatgttgaa accatgggca
    11881 aatccaactg cgtttccagc ttccaagttt ggagcgattt ctgcttcgta caattcttgt
    11941 tgaatttcgt ctggcgccaa gatcatgata acatcagcca acttagtagc ttctgctact
    12001 gtgtaagtat caaatccatc ttcttttgct ttatcaaaag atttacctgg acgtacacct
    12061 ataataacgt cacgacctga atcacgcaag ttttgagcat gcgcatgccc ttgtgaacca
    12121 taaccgataa cggcgatttt tttaccgtca agtgctgcta ctttaacatc tttttcatat
    12181 tccatttgaa ctgtcatagc ttttctctct tttctattat ttattgcctt ttaggctggt
    12241 ttaataaatt taagttggat ttttaatcgc gggtaaatcc agttgcaccc gttcgagcaa
    12301 tattgcgaat accgtatggg cgaatgactc tcaatagggc ttcgctcttt tctgcatttc
    12361 ccgtcatctg aatggtaatc gagcttggcg ctacgtctac cactgttgca cggaaaggtt
    12421 gaataatcgc taaaatctca gctctcttct cagctggcgc tgacatctta accaaaatca
    12481 cctcgcgctc caaatgaggc ttgtctgtaa tatctcgaat gcgaatcaca tcaatctgac
    12541 gattgagctg tttgatgatt tgctccactt catcatgaga agcaacatca ataataatag
    12601 tgatacgcga tacattcgga tcttctgttg ctccaacaga gatgctttca atattaacct
    12661 gacgacgaga taggacacct gtaaagcgat tgaggactcc tgaacgattt tgtagttttg
    12721 ctgttaacat tctacgcatg gaactgcacc cccaacatct catgattact cttaccagct
    12781 ggtaccattg gtaacacctg ttccttacga gaaatatcta cctcaattag cataggaaca
    12841 tcctcagtga tgacttcaag gtcttgagcc aaggtctcag gattgtcaaa cttatagttt
    12901 ttaataccat aagcctgcgc catcaattgg aaatcaggaa gggtatcaaa gaccgactct
    12961 gatgttctgc cttcatagaa ggattcctgc cactggcgaa ccattccaag tgaatgattg
    13021 ttcagcataa ccaccttgat tggcaccttg taaatattca aaatagccaa ctcctggttg
    13081 gtcatttgga aaccaccatc cccaacaaac aagactactt ccttatctgg gttagcaatt
    13141 ttagcaccga ttgctgctgg aattccaaag cccattgttc ccaaaccacc tgaagtcact
    13201 aactgacgtt cattttggta gggataatac tgagctgtcc acatttggtg ttgaccaacg
    13261 tctgttacca caatggcatc tccattcgtc aattcaccaa ttcgttcaat aactgcttgc
    13321 ggttgaacca cacgctcttt cttgtcataa gaacgaacac gattcttgtc tttagtgact
    13381 ttctcaatcc acttttcagt attgttgtga actgttggtt ctgctagcaa catttgcaag
    13441 gccttcttag catctccaac tacaggaatg tctgcactga taatcttgcc aatctcagct
    13501 gggtcaatat caatgtgggc aaccttagca ttcttagcga aagtcttagg attccccgtc
    13561 aaacggtcat cgaaacgaga accaatacta atcataaagt ccgcttccgt catggcaata
    13621 tttgctgcga atgacccgtg catgcctccc attccaagaa agagtgggtg actcgttgca
    13681 atcgttcctt gtcccaaaag actggttacc actggaattt gatagcgttc tgcaaattca
    13741 tttagttccg tagcagcctc agcataacta attccaccac cagctaacaa gactggcttt
    13801 ttagccttgg acaattgctt caagattttc ttgatttgca tatcattcgg ctcaagagtc
    13861 ggctgataac ttggtaaatt cacttctggt gaataaatga aatctgtttc taaagcagat
    13921 atgtcttttg gtaggtcaat tacaactggc cctggacggc ctgtagttgc gatatggaca
    13981 gcttccgtaa tgatacgcgg aatatcagct gtctcacgaa cttggtaatt gtacttagtg
    14041 attggcatgg taattcctac gatgtctgcc tcctgaaagg catccttccc aatccctgct
    14101 cgcgccacct gacctgtaaa gaccaaaagg ggaacgctat cgctcatagc atccgcaatc
    14161 cctgtaatgg catttgttgc tcctggtcca ctagtgacga cggcaacacc caactttcca
    14221 gttgatttgg cataaccttc agcttcatgc aaacaacctt gctcatggcg ccctagaatg
    14281 tggcgaatgc ctttaaaatt atatatcgca tcataaaaag gcaaaaccgc accaccagga
    14341 taaccaaaga tggtatcagc tcctaaatca cgaagtgttt ccaaaactag gtccgacccc
    14401 gtcttaggag attctaaact gattttctcc attgttcccc tttctttcct cttaaaaata
    14461 acttgttact atcataccat tttttcaaaa tttttcaaga taaaagaaga aattttctga
    14521 attttctatt ttaacgttta tttatgaatg ttatttttgt ttttattaaa aagataccga
    14581 tttcatttac taaaaaagaa aaaagaactg atttctcagt ccttcattaa tcggctctat
    14641 aatatttgta gtgggtaaat cc
//
LOCUS       DAVLUM010000050        14288 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLUM010000050 DAVLUM010000000
VERSION     DAVLUM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.050"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            8..1009
                     /locus_tag="VYN42_001464"
     CDS             8..1009
                     /locus_tag="VYN42_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1462519.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1221..1450
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1617..1691
                     /locus_tag="VYN42_001465"
                     /pseudo
     CDS             1617..1691
                     /locus_tag="VYN42_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2150..3511
                     /gene="trpE"
                     /locus_tag="VYN42_001466"
     CDS             2150..3511
                     /gene="trpE"
                     /locus_tag="VYN42_001466"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1462520.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLHVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3508..4074
                     /locus_tag="VYN42_001467"
     CDS             3508..4074
                     /locus_tag="VYN42_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1462521.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4085..5089
                     /gene="trpD"
                     /locus_tag="VYN42_001468"
     CDS             4085..5089
                     /gene="trpD"
                     /locus_tag="VYN42_001468"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1462522.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5086..5853
                     /gene="trpC"
                     /locus_tag="VYN42_001469"
     CDS             5086..5853
                     /gene="trpC"
                     /locus_tag="VYN42_001469"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1462523.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            5840..6439
                     /locus_tag="VYN42_001470"
     CDS             5840..6439
                     /locus_tag="VYN42_001470"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1462524.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVDLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            6417..7640
                     /gene="trpB"
                     /locus_tag="VYN42_001471"
     CDS             6417..7640
                     /gene="trpB"
                     /locus_tag="VYN42_001471"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1462525.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7633..8409
                     /locus_tag="VYN42_001472"
     CDS             7633..8409
                     /locus_tag="VYN42_001472"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1462526.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8381..8482)
                     /locus_tag="VYN42_001473"
                     /pseudo
     CDS             complement(8381..8482)
                     /locus_tag="VYN42_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            8711..9442
                     /locus_tag="VYN42_001474"
     CDS             8711..9442
                     /locus_tag="VYN42_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462527.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQIWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTFYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            9457..10608
                     /locus_tag="VYN42_001475"
     CDS             9457..10608
                     /locus_tag="VYN42_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1462528.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(10660..11319)
                     /locus_tag="VYN42_001476"
     CDS             complement(10660..11319)
                     /locus_tag="VYN42_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1462529.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLSQVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            11389..11835
                     /locus_tag="VYN42_001477"
     CDS             11389..11835
                     /locus_tag="VYN42_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462530.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            11875..12147
                     /locus_tag="VYN42_001478"
                     /pseudo
     CDS             11875..12147
                     /locus_tag="VYN42_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12257..12460)
                     /locus_tag="VYN42_001479"
     CDS             complement(12257..12460)
                     /locus_tag="VYN42_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1462531.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(12491..13099)
                     /locus_tag="VYN42_001480"
     CDS             complement(12491..13099)
                     /locus_tag="VYN42_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1462532.1"
                     /translation="MSNEKNINTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(13138..13308)
                     /locus_tag="VYN42_001481"
     CDS             complement(13138..13308)
                     /locus_tag="VYN42_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1462533.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(13320..13886)
                     /gene="amaP"
                     /locus_tag="VYN42_001482"
     CDS             complement(13320..13886)
                     /gene="amaP"
                     /locus_tag="VYN42_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1462534.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(13970..14134)
                     /locus_tag="VYN42_001483"
     CDS             complement(13970..14134)
                     /locus_tag="VYN42_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1462535.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
BASE COUNT         4507 a         2553 c         3089 g         4139 t
ORIGIN      
        1 gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg cacgtttatc
       61 aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg ttaaagaaga
      121 aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa atgcgtatgc
      181 aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa aaatcgactc
      241 ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt gtaaagaatt
      301 tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta attcaattat
      361 atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg tagatgatat
      421 cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg aatctcaaac
      481 gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata tgatgaaagc
      541 tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg gggggagaat cccatgtgaa
      601 taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact ttatggattt
      661 aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa tgcagcactt
      721 gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg ttcagggctt
      781 gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta ttattggatt
      841 tgataatatt cctatttctc agtattatac tccagctttg tctacaattg ctcccaatta
      901 tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag gggaaagtgt
      961 cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt attgtttaat
     1021 tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt tagcctccat
     1081 tcagtttcta ttgagttgga tccaatttct aacaagtggg acatgttcat gttcgatcta
     1141 aggaagacat ggtcacattc gaatgatatt ttcaaaaaaa tcgtaaaaaa gtcttgacaa
     1201 agaaaaaaca aagtattaaa ataagttcaa caaatcagaa aagtaactat ttttgatctt
     1261 cagggagcct gtggtggttg tgaataggtg gttggaagta gtgaaagtgg gctgattttg
     1321 aaaatgaatt tgaaacaatg aaaattcggt gcgcacacct tacagtgcag cttgttgtta
     1381 aacaaggcag agatgtaaag ggatagtccc tttataattg aggtggcacc gcgttaccaa
     1441 cgccctcaca cggaagtata ttctgtgtgt gggctttttt ctatccgtcg tttggtttat
     1501 cttttattag ggccttaagt cgctttgatg aacttgagtt ctatctacag ctccttgcct
     1561 actactaaaa gcaaacaaaa aggctggact aatacgaaaa aagctagtaa tactcaatga
     1621 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaaacactgt tttgaggttg
     1681 cagatagaac tgacgaagtc agtaaccata cctacgataa ggcgacgttg acgcggtttg
     1741 aagagatttt cgaagagtat aaaggtgtac cgagatgaac atctcttcat caatgtctct
     1801 ggtcgtggag gcaaggacct agctgcgatt gcagactact agaagctaaa aaataataga
     1861 tggaaaaatt acagttcttt ctctcacaga gagcttgtgg ttgctgaaaa caagcagaga
     1921 aagctgtaaa gttgggttca tctgaaacga gagaagaaaa catcattctc aagggagtgc
     1981 cctttatcgc acagcctgtt acaggagata tctgagacag gaatgagaga taggagaaat
     2041 cctataattg aggtggcacc gcgaatttcg tcctcacgca agttattttg cgtggggatt
     2101 tttcatacag tcaccacgga ctagaagtag aactgaaagg gaaattacaa tggaacgaat
     2161 cattcatgga gatgtcttat caccaatctt ggcttatatg cgcttaaagg ggcaacataa
     2221 ggttatttta gagagtattc cgagagacaa ggaaacagct cgtttttcta tcctagccta
     2281 taatccagtt tttgagatta agtttgaaaa tggggttctc tatcaaaatg gtcaagtgat
     2341 tgatcgggat cccttggatt tcctttatga agtgattcat aagagtcagc accactcaga
     2401 gctacctttt ggtggtggag ccattggttt tgtgggttac gatatgattt cgctttatga
     2461 agaaattggt caaatccctg aggatacaat tgggacgcca gacatgcatt tctttgtcta
     2521 tgagagctat atggtctttg accacaagaa ggagaagata catgtcatag aggatgcact
     2581 ttatagtgag cgcagtcaag aggccttgga aaaatccttg aaccaagtgc ttgaggaatt
     2641 acgcattcct gctccaaatg aatttgaaga tttggatcta tctccgttag acttcaaacc
     2701 gcatatcgct ccacataagt ttgagggaat ggtagaaaca gctcgtgact tgattcgtaa
     2761 cggagatatg ttccaatgtg tactcagcca gcgtttctca gcagaagtta ctggaaatcc
     2821 atttgacttc tacagaaatc tccacgtaac taatccttct aattaccttt atttctatga
     2881 ttttggggat tatcaaatca tcggagctag tccagaaagt ttggtttctg tcaaaaatgg
     2941 catcgtgaca accaatccga ttgcagggac gcgaccaaga ggggctacgg atgaagaaga
     3001 caaggccttg gcgactgacc tcctctctga tgagaaggaa acagcagaac atcgaatgtt
     3061 ggtagacttg gggcgtaacg atattggccg catctctgaa acgaccagtg tccaagtcac
     3121 taagtatatg gaagtggagc tcttccgtta tgttatgcat ctgaccagcg tggtcaaggg
     3181 gcgtttgctt ccagaactca ctgccatgga tgccttgaaa gctacacttc ctgctggaac
     3241 cgtttctgga gcgccaaaga ttcgagcgat gagacgcatc tatgaactgg aaacggaaaa
     3301 acggggcgta tatgcaggag caatcggcta cttgtctgcg acgggtgata tggatttggc
     3361 cattgccatc cgaaccatga ttctcaaaaa tcaaagagcc tatgtgcagg ctggggcagg
     3421 gattgtctac gactctatcg cccaaaacga ataccaagaa accattaaca aagcaaaatc
     3481 tatgactaga attggagaac taagaccatg attttattga ttgacaacta tgattctttt
     3541 acctataact tggcccaata cattgggaat tttgcagaag ttcaggttct gagaaatgat
     3601 gattccaagc tgtatgaaga agctgagaaa gcagatggtc tggtcttttc tcctggtcct
     3661 ggttggccag ttgatgctgg aaagatggaa gacatgattc gtgattttgc aggcaagaag
     3721 ccgattcttg ggatttgttt gggccaccaa gccattgcag aagtctttgg tggtaagcta
     3781 ggtttggctc caaaagtcat gcatgggaaa cagagcaata tcaactttga agcgccatct
     3841 gttttgtatc aaggtattga ggaaggacgt gcggtcatgc gttatcacag tattttgatt
     3901 gaggaaatgc cagaagactt tgaagtgaca gctcgttcga ctgatgacca agccatcatg
     3961 gggattcaac ataaaaacct accgatttat ggcttccagt accatccaga gagcattgga
     4021 acgccagacg gcttgtcttc tattcggaat tttatcgaga aggttgtaaa gtgaggaaac
     4081 taggatgaaa gagattattg aaaaactagc aaaatttgaa aatttatcag gtgtggaaat
     4141 gacggatgtc attgagcgta tcgtaactgg gcgtgtaact gaagcgcaga ttgcttctct
     4201 cctcttagct cttaagatga agggggaaac acctgaagaa cgcacagcca ttgcccaagt
     4261 catgagagga catgcccagc atattccaac tgagattcat gatgccatgg acaactgtgg
     4321 tacaggtggg gacaagtctt tcagttttaa tatttccaca actgcagcct ttgtcttggc
     4381 tggtggcggt attcacatgg ccaagcatgg taaccgctcg atttcttcta aatctggttc
     4441 cgcagatgtc ctcgaagcct tgggaatcaa tcttgacctc aaaccagctg aactaggtaa
     4501 ggtctttgat aaaactggaa tcgtctttct cttcgctaaa aatatgcacc cagctatgaa
     4561 atacatcatg ccagctcgtt tggaattggg aattccaacg attatgaact tgactggtcc
     4621 actgattcat ccaatggctt tagaaacaca gcttcttgga attagtcgtc cagaactcct
     4681 agaaagtaca gctcaggttt tgaaaaatat gggtcgcaaa cgtgccatcg tggttgctgg
     4741 accagaaggg ttggatgaag ctggcttgaa cggaacaacc aagattgcac ttcttgaaaa
     4801 tggcgaaatc agcttgtcaa gctttactcc agaggatttg ggaatggaag gctatgctat
     4861 ggaagatatt cgtggtggga atgctcagga aaatgcagaa attttgctta gcgttctgaa
     4921 aaacgaagca agtccattct tggaaacgac agtcttgaat gctggtcttg gtttctatgc
     4981 taatggtaag attgatagca tcaaggaagg agttgccttg gcccgtcaag tgattgctag
     5041 aggcaaggcc cttgaaaaac tcagactgtt acaggagtac caaaaatgag tcaggaattt
     5101 ttagcacgaa tcttagagca gaaggtgcgt gaggtggagc agatgaagct ggagcaaatc
     5161 cagcctctgc gccagaccta tcgcttggca gaatttttga agaatcatca ggaccgcttg
     5221 caggtaatcg ctgaggtcaa gaaagctagc cctagtttgg gagatatcaa tctcgatgtg
     5281 gatattgtgc aacaggccca gacttatgaa gaaaacggag cagtgatgat ttcggtgttg
     5341 acagatgagg ttttctttaa agggcatttg gattatctac gggaaatttc cagtcaggta
     5401 gagattccga cgctcaacaa agactttatc atcgatgaaa agcaaatcat ccgcgctcgc
     5461 aatgcaggtg cgacagttat cttgctcatt gtggcagcct tgtccgaaga acgcctcaag
     5521 gaactgtatg actacgcgac agagcttggt ctggaagtct tagtggagac tcacaatcta
     5581 gctgaactag aggtagccca cagacttggt gctgagatta tcggggtcaa caaccgcaac
     5641 ttgactacct ttgaggtcga cttgcagacc agtgtagatt tagcccctta ctttgaggaa
     5701 ggtcgctatt acatttctga atctgccatt ttcacagggc aggatgcgga acgactagcc
     5761 ccatacttta acggaatttt ggtagggaca gctcttatgc aggcagaaaa tgtggcccag
     5821 agaatcaagg agttgcagat tgacaaaggt taaaatttgt ggactatcga ccaaagaagc
     5881 ggtggaaaca gccgtttcag caggagccga ctatatcggt tttgtctttg cacctagtaa
     5941 aagacaggtg actttagaag aggtagctga gttggcaaag cttattcctg cagatgtgaa
     6001 aaaggttgga gtatttgttt caccaagtcg ggtagaactg ctggaagcga ttgacaaagt
     6061 tgacttggac ttggttcaag ttcacggtca ggtggcagat gatttatttg agaatttgcc
     6121 ttgtgccagt attcaggctg tgcaggtaga tggaaatggg catgtcccca attctcaggc
     6181 agattatcta ctctttgatg cccctgtggc aggaagtggc cagtcctttg attggggtca
     6241 actggatacg actggattac ctcagtcttt ctttatcgca ggtgggctta atgaagacaa
     6301 tgtagtaaaa gcaattcaac actttactcc ctatgcagta gatgtatcaa gcggagtgga
     6361 gacagatgga caaaaagatc atgaaaagat tagaagattt atagagaggg taaagaatgg
     6421 catatcaaga accaaataaa gatggatttt acggaaaatt cggcggacgt tttgtcccag
     6481 aaacattgat gacagcagtt ttggagttgg agaaggccta ccgtgaaagt caggcagacc
     6541 caagtttcca agaggaatta aaccaacttt tgcgccagta tgtgggacgt gaaactcccc
     6601 tttactacgc aaaaaatttg acccagcata tcggcggagc caagatttat ctcaaacggg
     6661 aagaccttaa ccatacagga gcccacaaga ttaacaatgc cttaggacaa gtttggcttg
     6721 ccaaacgcat gggtaaaaag aaaattatcg cagaaacggg tgctggtcag cacggtgtgg
     6781 caactgcaac tgctgcagcc ctctttaata tggaatgtac catctacatg ggtgaggaag
     6841 atgtcaaacg ccaagctctc aatgtcttcc gtatggagct tttgggagct aaggtcgagg
     6901 ccgtgacaga tggttcgcgc gtgctcaagg atgcggtcaa tgcagccctt cgttcatggg
     6961 tagctaatat cgatgatacc cactatatcc ttggttctgc cttggggcct catccatttc
     7021 cagaaatcgt tcgtgacttc caaagtgtca tcggtcgaga ggctaaacaa cagtaccgtg
     7081 acttgacagg tcgagatctg ccagatgccc tagtagcctg tgttggtggt gggtcgaatg
     7141 ctatcgggct cttccatccc tttgtagaag atgagtcagt agctatgtat ggaactgaag
     7201 cagcagggct tggtgtggat acagagcacc acgctgctac cttgaccaag ggtcgtccgg
     7261 gagttcttca cggttctctc atggatgtgc tccaagatgc ccatggtcaa attcttgaag
     7321 ccttctctat ctcagcaggt ttggactatc ctggtattgg tccagaacat tctcactacc
     7381 acgatatcaa acgtgccagc tatgtccctg tgacagacga agaagccttg gaaggattcc
     7441 aactcttgtc tcgtgtggaa gggattatcc cagccttgga atctagccat gctatcgctt
     7501 ttgcggtgaa attggccaaa gaacttggac cagaaaagtc tatgattgtc tgcctatcag
     7561 gtcgtgggga caaggatgtg gttcaagtca aagaccgctt ggaagcagat gcagcaaaga
     7621 agggagaagc tcatgcctaa gacactaaca gaaaaattaa atgctataaa agcagctgga
     7681 aaaggaattt ttgttcccta tatcatggct ggagaccacg agaaaggttt ggatggacta
     7741 ggagaaacaa tccactttct agaagatttg ggtgtctctg caattgaagt gggtattccc
     7801 ttttcagacc ctgttgcaga tggacctgtt atcgaagaag ctggcttgcg cagtttagcc
     7861 cacgggacct ctacccaggc tttagttgaa accttgaaaa ccattgaaac agagattcca
     7921 ctggtcatca tgacctactt caaccccctc tttcagtacg gtgtggagaa ctttgtcaaa
     7981 gatctggctg atacagctgt gaagggcttg attatcccag acttgcctca tgaacatgcc
     8041 aactttgtag aaccattttt ggcagataca gatatcgcct tgattccttt agtaagcttg
     8101 accacaggaa ttgagcgcca gaaagagttg attgaagggg cggagggatt catctatgcc
     8161 gttgccatca atggagtgac agggaaatca ggcaattacc gtgcagattt ggacaagcac
     8221 ttggcgcaac ttcatcaagt ggccgacatc ccagtcttga caggttttgg tgtatctagt
     8281 caagccgatc tggaacgctt caatgcggtg tcagatggtg ttatcgtcgg ttcgaaaata
     8341 gtaaaagctc tccaccaagg agagccgatt caggacttta tcaaacaagc agtagcttac
     8401 caaaaataat caaacaagta gcaagtaaga ggaaaggcac gaaaggaagt ctttcctttt
     8461 tcttttgcag gagaaaggct agttttatag tgaattgaat ctggaatatt acactacggt
     8521 tcctaaaata ttttcagaaa gcgatttgaa tttcccaata aatttgttca gtttttaatt
     8581 gattttacta tagaagatat aattttctaa attactctga cacagaactt taagaaaaag
     8641 ctaattattg tagtaatttc tttaagaaaa tgatataatt cattaaaaag tatttggagg
     8701 aggaagaatt atgttgaatc aggatctctt tgattcgctt gaggcacaaa aaattgtaga
     8761 tactttgatg aaagggcaaa aagattatgt agatgaacgt ctagaaaaaa gagagacaat
     8821 gatagtgtcg aatggttatg catggacgcg acctaatcat attgatactg catttgcatc
     8881 agcagatttg tttgagtata aattacaatt agcaggacag atttggggat atttagaatt
     8941 tgaaacaaat acagaaaaat atgggaaagt attgttaatt ataaagggta agaagcgact
     9001 tacgaaccaa tttcctttgg tacaaaaaaa taagagtggc tacttatttg aatatgctca
     9061 gatgaataca ttttatctta atcaacattc ttcctacaaa aatgatgaag atagtcattc
     9121 ctttccaatt cagatggagt tagtttctga tgaaatgatt caagaaattg aacaagctac
     9181 taaaaattcg aatatcgaaa aatttatgat tttaacttat gaggcggact cagaaaacaa
     9241 tattatatct gtagatgttg ttatgcctga tgcacgaact ggtcagttac acttgattca
     9301 agatttgtct gagtatattc aatcaagttc gtaccatttc gaagaagcta aatatcaaga
     9361 tattcctaat ttttcagaat tatcggaaac agaagatttt gaaattattc caagaataga
     9421 aaaacaagaa ggtcaaaagt agtaaggagt atgtaaatgt ttaatggtcg ggtattgaaa
     9481 gaattacggc tgttaaatgg tttaagtaga gcagaattag ctcagagaat taatttaacg
     9541 gaacaagcca tttggcagtt tgagtccaac gaaacgaaac ctaaattatc aaccaaaatg
     9601 catttggcca accaatttca tgttgattta acttattttg aacaggaaga agagagcatt
     9661 cgatttgatt cttctgtaat tgcctttaga aatgcagacc tagcaacacg gaaaacaata
     9721 gatattcaaa ctatgtattt acataaggta gatagtttga ttgattattt tgaaagtttt
     9781 gtaattatac ctaatattac aattcatgac ctaagtaatg tagtgagtga atcttatcat
     9841 aagggagaat ccattgagga attggctctt tatgccaggg aaaaattagg tatttcaaaa
     9901 gataatcatg atttgcttta taaattagaa cgttcaggca tctatatcgt ggaacgatta
     9961 attaatggcc aagctgatgc ttatagcgca tggtcaaaat tgggaagacc ttatattgtg
    10021 ttgggaacga ataaatcatc tgtacgtcga aattttgact tagctcatga gctaggacat
    10081 attcttttac acaaatataa agatatgaat gaagatggca atcgtttgga gcaagaagca
    10141 aattattttg catcatgttt tttattgcca aaagaagagt ttttagtcaa atttgaagag
    10201 agggttggca agcgtgtcag caatcctgat agttatattt tattgaagtc ggatttgaat
    10261 gtttcgatac aggctttaga gtatcgagct tttaagttag gattattgac tccaaagcaa
    10321 cattcttact tttatcgtca aattgcgcaa aaaggttaca aaatgattga acctttggat
    10381 gatcaaattt ttgttaaaaa accaagcaaa gtaaagagta ttctggacgt cgttttgagt
    10441 aatcatctag tcagtctagc gactataatg tctaaacaaa gtattcgttt acagtttata
    10501 agcgaaatat tttcagtcga aatgaaattt tttgatcagt atcaagaaga tagaagaaca
    10561 gatcgatttg ataacatcat ccctttgtac aaaagaaata atttataatt taactgtgaa
    10621 ataatttcat gaaggacata tggcagaaat tggattttat cagacaagca gtagcttacc
    10681 aaaaataatc acacaagcag caagtaagag gaaaggcacg aaaggaagtc tttccttttt
    10741 cttttgcagg agaaaggcca ggatacccgt cgcagaagcg aactgaatca agatcagtaa
    10801 ctccgttacg ctaaagacga gagcgcaaga agctaaaaaa aggaaatccc ctgcacccat
    10861 gcggatatcg ataaaatgag ccaaaattcc aagtatgagg aaggagacca tgaccagatt
    10921 ccagccagag gaagctatta ggattaggtg gaaagtcatc cagaccagta agggatattc
    10981 ctgatggcga aagtcgtaga tgcccaaggt caaaccagca gtgattagga tgacttgact
    11041 caaggaaagt aattcccaag agtaaagcag aaagaggagt cctaagccta gttcaaagag
    11101 ggcataccag acaggatagc ggaccttgca gtagcgacag caaaagcgat tgaagacctg
    11161 tgagagaatc ggaatcaaat ctaagggacg caagcgagtc tgacaggaat cgcagtgact
    11221 ggctgaactg ataatggatt gctctggaaa acggtcaatg accaaaccaa gaaaggaagc
    11281 gagaatgctc ccgacgagaa aaaaataaaa atcaatcata cttatctatt cgtaaaaaat
    11341 gggagaaata gtataatgga gaaacataga taaggtggtg aggaaaagat gacaattcgt
    11401 tttgaagaaa aggtgagcac agaaaacgct caatttgtat gccagtggtc caactcccta
    11461 ggcaaatcct ttcaagaaca atggatggga ccaaggattc cttttctact gacccttcaa
    11521 gccttggaag gagtcttttc aatctttgat gaacaagagt ttgtgggatt tatccagaaa
    11581 atcaggctag aagacagcaa tcttcatatc gggagatttt ttatcaaccc ccagaaacag
    11641 gagcaaggct taggtagcca ggctttaagg aaatttgtta gtttggcctt tgaaaatgaa
    11701 gatatagata gtatttctct aaatgtcttc gaggcaaatc aaagagctca gaatctttac
    11761 caaaaagaag gatttgaaat cgttcaaatg gttgaagcac ctgtacgaaa atatatcatg
    11821 aaaaagggga gatagaaagc aaacagcctt gaaatcaatg ttaactgcga ttatgaacct
    11881 gaatcagccc ctcaaaagag actgtatatg aatgaacgtt accagtgttt aaaaactaaa
    11941 gaatatcagg cacttttatc ttccaagggt agacaaattt tcgctaaacg taagattgat
    12001 atgaaatctg tctttgggca gataaaggtt tgtttgggtt ataagagatg tcatctgaga
    12061 ggtaagcgtc aagtgagaat tgacatggga ttcatactca tggccaacaa cctgctgaaa
    12121 tataataaga gaaagaggca aaattaaaaa gctagagttc cgcaattggg aatctctagc
    12181 tttttgtttt ctgagaatca tcttgactca gactcttttg actaatgtta ccaaaaagat
    12241 aaagtaactt ttaaccttat ttatcgtcgc cactcaacat gtttttaaca ccttctacag
    12301 caccttctac agcgtcttta gcgtcttcgg caacttcttt tactttagaa acaacttttt
    12361 cagctgctcc ttctttttcc attttttcat caccgatggc tttcccaaca ccttctttaa
    12421 tagaaccttt agcttgattt aatttttctt ctactgacat gataatttct cctgttatat
    12481 ttattttatc ttagtttaca cgagtgtttt cgtgagatac tacaccattt gctgcacctt
    12541 taacagcttc tacaccttcg ctaacttttt cttgaacagt tgagaaacca gatccaagac
    12601 cagatttagc tttttcgaat tgttctgaag tgaattctcc tgttgattca gcaacgtcag
    12661 atacgcgatc ttgaaggctt actgagtctg cttcatgctg ttctttagtt ttgatgtcga
    12721 caacgtttac gttgatttca acaatttcca agtcagtcat tttagcaact tctgaagata
    12781 cgatttctct gatttctgaa tataaagctg gaacattttt ttggtactca acaataacgt
    12841 ttaagtcaac tgcaacttgt gttttaccaa cttctacgtt aacaccactt gttacgtcat
    12901 cgctgttaac gattttttct ttaagatttg agaagaaacc accatcgatt cccaaaagac
    12961 ctgaaacgtt ttctagtgaa agaccaatga ttttttggat aactttatct tcgtaagtaa
    13021 gctccccttt gatttcgtga gctacaacag tagcatcttt cttttctacg ttagtgttta
    13081 tgtttttttc gtttgacata tgaaactcct ttaattaaat tagtaatttt tattttttta
    13141 tttatctata tagttttttt cgatatataa tccagctgca actcccagtg ctcctaaaat
    13201 caatacaaat attgttttga agaagccaaa ggagacaatc aaacaagcca gaaatacgcc
    13261 tatgagacca gcgataattg gatatcgata ttgtttaagc cattccattt tttacttcct
    13321 tacttcacac gactaacagt ctttttgttt tgaggttttg gttggtaatt ttttactgca
    13381 acttcaagtt ttacttgacg ctcaatacca aaaaactgct tcaatccatt agttatttca
    13441 ttttgaatta tttggcatct gtcagcgatg ttgtctgaag gaagaatttt accttctaca
    13501 tgaacgaaac atttattttt tcgtaaattt acatgaacag ttgggttctt gatcaatcta
    13561 tgatcactca ccaaacttct aacaaaacct tcgattgccg aattctttaa ttttaatgta
    13621 tcgtttttag tttcaagttg gatttccaag taacgcttag gataaaacat cacaactaaa
    13681 atggataata aaactaaagt tgatagaacc actgtccccc aaaagacata tctagcaaga
    13741 tagaattcaa ctacggagtt ctgtctccag ctaagtagat gaatacctag atcactaact
    13801 tgatgataat ctatcaaaac aggaaggaaa attgtcaaga ttaaaataca gaaaataatg
    13861 aaacatattt tctttgcttt tgacatatac aatcctttcg atttaacatt taaactattt
    13921 ttcccgtcat tgatttaaaa atagtttgct aactttactg gcgaaaagtt tactttctac
    13981 ctgtaaagaa tgacactaca gtaatcacaa tcgctgcacc tacaatagat gggagcaaag
    14041 ccattccagc gattgatgga ccccaactac ctaaaagaga ttgtcctgca tatgccccga
    14101 ctaaaccagc gaatacattt gcgatgattc ccatagaact acttttttag tgattttacc
    14161 tgccaagaga ccaataagac ctccagcaat aattgatcac aacactgcct accctccttt
    14221 tttattttaa tatcaaaaaa tcaatttctt tgattattac tattatataa ctttaatata
    14281 gaaaagtc
//
LOCUS       DAVLUM010000051        14049 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLUM010000051 DAVLUM010000000
VERSION     DAVLUM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.051"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            83..880
                     /locus_tag="VYN42_001484"
     CDS             83..880
                     /locus_tag="VYN42_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1462536.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVGMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLLGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VYN42_001485"
     CDS             1028..1150
                     /locus_tag="VYN42_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEV1462537.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            1172..2212
                     /locus_tag="VYN42_001486"
     CDS             1172..2212
                     /locus_tag="VYN42_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV1462538.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGVIVNSGRFDWAASGKFPQFVEEDPSYHNLSYTRDVGAAAFIIAVRVQLLCDTGA
                     ALSPFNAFLLLQGLETLSLRVERHVQNAEKIVDFLVKHPKVEKVNYPKLADSLYHALA
                     EKYLPKGVGSIFTFHVKGGEAEARKVIDHLEIFSDLANVADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2383..3657
                     /locus_tag="VYN42_001487"
     CDS             2383..3657
                     /locus_tag="VYN42_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1462539.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VYN42_001488"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VYN42_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1462540.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHHLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4787..5089
                     /locus_tag="VYN42_001489"
     CDS             4787..5089
                     /locus_tag="VYN42_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1462541.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVINFGLWIAKAPSQERGRLAFLQILAQTLQGFR"
     gene            5197..5835
                     /gene="udk"
                     /locus_tag="VYN42_001490"
     CDS             5197..5835
                     /gene="udk"
                     /locus_tag="VYN42_001490"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1462542.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5963..7303
                     /locus_tag="VYN42_001491"
     CDS             5963..7303
                     /locus_tag="VYN42_001491"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1462543.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7281..7493
                     /locus_tag="VYN42_001492"
     CDS             7281..7493
                     /locus_tag="VYN42_001492"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1462544.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7490..8365
                     /locus_tag="VYN42_001493"
     CDS             7490..8365
                     /locus_tag="VYN42_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1462545.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            8358..9173
                     /locus_tag="VYN42_001494"
     CDS             8358..9173
                     /locus_tag="VYN42_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1462546.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9166..9597
                     /locus_tag="VYN42_001495"
     CDS             9166..9597
                     /locus_tag="VYN42_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1462547.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9604..11271
                     /gene="recN"
                     /locus_tag="VYN42_001496"
     CDS             9604..11271
                     /gene="recN"
                     /locus_tag="VYN42_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1462548.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11273..12001
                     /locus_tag="VYN42_001497"
     CDS             11273..12001
                     /locus_tag="VYN42_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1462549.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDYPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12080..13903
                     /gene="lepA"
                     /locus_tag="VYN42_001498"
     CDS             12080..13903
                     /gene="lepA"
                     /locus_tag="VYN42_001498"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1462550.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         4152 a         2558 c         3357 g         3982 t
ORIGIN      
        1 acttttatga aatatagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gggatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgctgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg acttgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatctt ttatttttga
     1141 tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaataca aagcttgtct tgattgaaac cttgggtaac cccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattggt ggagtgattg tcaatagtgg
     1681 tcgttttgac tgggcggctt caggtaaatt ccctcaattt gttgaggaag atccgagcta
     1741 ccacaacttg agctatactc gtgatgtggg tgctgcagcc tttattatcg ctgttcgtgt
     1801 ccaattgctt tgtgatacag gtgcggcctt gtccccattt aatgcattct tgttattaca
     1861 aggacttgag accctctctc ttcgtgtgga acgccatgtg caaaatgctg agaaaattgt
     1921 tgatttcctt gtcaagcatc ctaaggtaga aaaagtaaat tatccaaaac ttgcagatag
     1981 tctttatcat gccttggctg agaaatactt gccaaaaggt gtgggttcaa tctttacctt
     2041 ccatgtcaaa ggtggggagg cagaagcacg aaaggtaatt gatcatttag aaatcttttc
     2101 tgaccttgca aatgtggcag atgctaaatc gcttgtggtc catccagcaa caaccactca
     2161 tggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatt aaatccactt
     2221 gtctatcgga cttgaaaatg tagatgattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaaga aaaagaagat aaacagtggt tttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggctctcttg gctaaggaca aggaagtaca ggctttggag
     2701 aaccaattgg ccactttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgtaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat taacttaaaa aaggaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgacgact
     3901 gaggatgcta gtggggaagt ggtcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctctta ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcatttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcctgat aaaaccccat actaaatagt agaatggttt
     4621 tgggaattat aatattccaa ttgttgcgag ttgtaggtac tcaaataatc tatatagaaa
     4681 tttagaggtg tgaaatgaag caatttaaaa ttctttcaga taaatattta gagtccatta
     4741 caggttctgg tgggaactta ggcccaggat ttggtgtgat aattctatga tgcgaaatga
     4801 gtttcgagaa agggtggagc aacttcttca acaaaaagaa ataaatgaaa atagtgagtt
     4861 gagtcacctg tttcgtcttg ctatacaaaa tttagacaga aatgaaaaat accaaacggt
     4921 catggccaat ttgagtcaag ggttgtcact ttacctcatg acgcatcatt accaggcacc
     4981 taagtctgtc attaattttg gtttatggat tgccaaagct cctagccagg aaagagggag
     5041 actggctttc ttgcagatac ttgctcaaac cctacagggc tttcgttaaa actgtcgaac
     5101 atcagaggga agactctggt gttttttgct gatgagacta taaattttgt aaaaaatgtg
     5161 atagaataga cgacggataa aataacggag gatagcatgc aaaatagacc aatcattatt
     5221 ggagtgacag gtggttctgg tggtggtaaa accagtgttt caagagccat tttatcgcat
     5281 tttcctgatg aaaagatttc catgattgag catgattcat actacaagga tcagtctcat
     5341 ttgacctttg aagagcgtgt caaaaccaac tatgaccatc cttttgcctt tgatacagac
     5401 ttgatgatcg agcagattaa ggaattgttg gcagggcgtc cggtggacat cccgacctac
     5461 gactatacag agcatacacg gagtagcaag acctatcgtc aggagcctca agatgtcttt
     5521 atcgttgagg gcattttggt cttggaggac aagcgtctgc gcgatttgat ggatatcaag
     5581 atttttgtgg atacggatga cgatgtgcgc attattcgtc gtatcaagcg tgatatggag
     5641 gagcgtggcc gtagccttga tagcgttatt aaccagtact taggtgtggt caaaccaatg
     5701 taccaccagt ttatcgagtc aactaagcgt tatgctgata tcgtcattcc tgaaggggtt
     5761 agcaataccg tggctatcga cctgttgacg accaagattg caaagatttt ggaagaagct
     5821 cgaaacagca aataatcaca tgtggaggcc ttgcctcctt tttctatttt tccctcataa
     5881 tggtacataa atggagattt ttaggcatat ttttggtata ataataccca tgaaagagca
     5941 agtaaatgaa tagtaggtgg agatggaaaa gtatttatcg gtaacaactt tgaccaagta
     6001 tctgaaaatg aaattcgata aagacccata cttggaacgg gtctatttaa ctggtcaagt
     6061 ttccaacttt cgtaaacgac ctactcacca atatttctcc ctaaaggatg accatgcagt
     6121 tattcaagcg accatctggt ctgggattta tcagaaatta gggtttgacc tagaagaagg
     6181 aatgaagatc aatgtgattg ggcgtgtaca ggtctatgaa ccaagtggta gctactccat
     6241 catcattgaa aaagctgagc ctgatggggt tggggcgctt gcgattcagt ttgaacaact
     6301 taagaaaaaa ttgacagaag aaggcctgtt tcaagaacgc ttcaagcaag ctctacccca
     6361 attttctaag agaattgggg tagtaaccag ccgtagtgga gccgttattc gagatattat
     6421 cacgaccgtc agcaggcgat tcccaggtgt tgacatcctt ctttatccga ccaaggttca
     6481 aggtgaaggg gctgcggagg aaattgcaag aaatattgcg cgtgctaatc aacgggacga
     6541 tttggatttg ctcattattg gtcgtggagg tggttctatt gaggatctct gggcctttaa
     6601 cgaagaaatt gtggtacgag ctatttttga atctcgtttg ccagttatct ctagtgtggg
     6661 gcatgagacg gatgtgacct tggcagattt tgtggcagat cgacgcgctg caacgccaac
     6721 agcggcggct gaactggcaa cacctgtgac caagttggat gtattaactc atttgcaaaa
     6781 tcaggaaaaa cggatggcaa cggcagtccg aaatgttcta tctaagaaac aagaggcttt
     6841 gaaaaaatgc agtcagtctg ttatctttag acaacctgag cgcttgtatg acggttattt
     6901 gcaacgcttg gaccaactgc aactgcgttt gaaacaaagt ttgcgaactc ggatttctga
     6961 taacaaacaa ttagttcaag caagaactca tcaattagta caattatcac ctgttaccaa
     7021 aatccaacgc tatcaagacc gtttaggaca gttggacaag ctcttaggta gccaaatggc
     7081 gttagtttat gacgccaagg ttgctgaggc caagcgactt tcggaagctt tgctcatgtt
     7141 ggatactagc cgaatcgtgg cgcgtggtta tgctattgtc aaaaaagaag agtccgttgt
     7201 agattcggtt gagagtttga agaaaaaaga ccaagtaacg cttttgatgc gagatggtca
     7261 agtagaatta gaggttaaag atgtcaaaac aaaagaaatt tgaggaaaat ctagcagaac
     7321 tggaaaccat tgtccaaagt ttggaaaatg gtgaaattgc tctggaagat gcgattactg
     7381 cctttcaaaa gggcatggtc ttgtcaaaag agctccaagc tacgctggac aaggctgaaa
     7441 agaccttggt caaggtcatg caagaagacg gaacagaaag tgattttgaa tgaaaaagca
     7501 agaaaaatta gctcttgtcg agtcggcttt ggaagatttt tatggagacc agcagtttgc
     7561 ctctagttta cgggagtctg ttctctattc tattcatgct ggtggcaagc gtattcggcc
     7621 ttttctattg ttagaagttc tggaagcctt gcaggttacc atcaaacctg ctcacgcgca
     7681 ggtagctact gccttggaga tgattcatac agggagcttg attcacgatg accttcctgc
     7741 tatggatgat gacgattatc gaagagggcg gttaaccaat cacaagaaat tcggtgaagc
     7801 tatggccatt ttggctggag atgccttatt cttagaccca tatgccttga ttgcgcaggc
     7861 agatttgcca agtcagatca aggtggactt gattgccaac ttatcccttg cttcaggtag
     7921 tctgggtatg gtggcagggc aagttttgga tatggagggc gaacaccagc acttgtcttt
     7981 ggaagaactt cagactattc atgccaataa gactgggaag ttactagcct atcccttcca
     8041 agcggcagct attatagctg aattgtcacc tgaaatgcag gtgaagctga aaactgtggg
     8101 tgaattgatt ggacttgctt ttcaagtcag agatgatgta ctggatgtga cagctagttt
     8161 tgaggaaatc ggcaagacac ctcaaaagga tctgcaggca gaaaaatcaa cctatcctgc
     8221 cctgttgggc ttggaagagt ccattgcctt ttgtaaccaa accctggatc aagctaatga
     8281 aaaattagaa gaaattgccc agcagattcc ctttgaaaca gaatcgattg taagtgtagt
     8341 agaaagtttg agaatcaatg gctaaggaaa gagtggatgt actagcttat aaacaggggt
     8401 tgtttgaaac gagagagcag gccaagcgag gtgtgatggc tggcctagtc gtagcagtcc
     8461 ttaatggaga acggtttgac aagccaggag agaaaattcc agatgacacc gaattaaaac
     8521 tcaaggggga gaaactcaag tatgtcagcc gtggtggttt gaaactggaa aaggccttgc
     8581 aggtctttga tttgtcggtg gatggcgcga ctacgattga tatcggggcc tctactggag
     8641 gttttaccga tgtcatgcta cagaatagtg ccaagttggt ctttgcagtc gatgttggta
     8701 ccaatcagtt ggcttggaaa ttacgccaag acccacgagt tgtcagtatg gagcagttca
     8761 atttccgcta tgctgaaaag actgatttcg agcaggagcc gagctttgcc agtattgatg
     8821 tgagtttcat ttcccttagt ctgattttgc cagccttgca ccgtgtcttg gctgatcaag
     8881 gtcaggtggt agcacttgtc aaacctcagt ttgaggcagg acgtgagcag attgggaaaa
     8941 atggaattat tcgagatgct aaggttcatc agaatgtcct tgaatctgta acagctatgg
     9001 cagtagaggt aggtttttca gtccttggct tggacttttc tcccatccaa ggtggacatg
     9061 gaaatattga atttttagcg tatttgaaaa aagaaaagtc agcaagcaat cagattcttg
     9121 ctgagattaa agaagcagta gagagggcgc atagtcaatt taaaaatgaa taaaaaagag
     9181 agacttgaaa aaattagaag attggtgaca gattatcaaa tcggcacgca agaagaaatt
     9241 gtagaacatt tgaaagaagc aggtatcact gccactcagg cgacggtatc ccgagatatc
     9301 aaagagttag gtattgtcaa aattcctttg agagacaaca cctatgtcta cgaattgcca
     9361 aaatcaatcg taaaaagtct gcaactggct gaagacaata tcgaatcggc tgaattgatg
     9421 gataagatga tcaatctcca agttattcca ggaaatacgg cttttgtaaa agctcagtta
     9481 atcgatactt ttgcagacaa gatttttagt tgtttgactg atgatagctc gattttagtc
     9541 attgccagaa gtggaagtct agcagaggaa atctttgaac aagtaaaaaa ttggtaggtc
     9601 tatatgttac ttgaaatttc gataaaaaac tttgccatta ttgaggctat ttccctcaat
     9661 tttgaaaagg ggatgactgt cctgactggt gaaacgggtg cagggaagtc gattatcatt
     9721 gatgccatga atatgatgtt gggagctcgt gcgacgacag atgttattcg tcatggtgca
     9781 ccaaaggcag agattgaggg gcttttctca gttgagaata gtcgtctttt acaggaaatt
     9841 tttgatgagc aaggtttaga gttaggtgat gaaattatca tccgtcggga aatcttgcaa
     9901 aatggtcgta gtatcagccg tgtaaatggt cagatggtta atctgtctgt tttgcgagct
     9961 attgggcaac atcttgtaga tattcatggt cagcatgacc atgaggagtt aatgcgtccc
    10021 caactgcata tccagatgtt ggatgaattt ggtgatgccg ctttttggga cttgaaagaa
    10081 acctatcaaa cgagttttga tgcctatcgg aaaatgcgca agcaggttct ggaagtcaag
    10141 aaaaaccaac aggaacacaa ggcacgtatc gaaatgttgg aatttcaaat ggcagagatt
    10201 gaggcagcaa acttgcaggc tggagaagac ttggatctca atcaagagcg agataaactc
    10261 ctcaaccaca aaaatattgc ggatacactg accaatgcct acagtatgtt ggacaatgaa
    10321 gatttttcaa gtctggccaa tgttcgttca gccatgaatg acatggaaag tgtcgaagag
    10381 tatgaccctg aataccgtga aatttcaagc tctctgtctg agacctacta tgttttagaa
    10441 gacattagca aacgtttgga agctatcatt gaggaccttg attttgatgg caatcgcctc
    10501 atgcaggttg agaatcgttt ggacctcctt catactatta ctcgtaagta tggtgggact
    10561 gttgatgatg ttttgcttta ttttgccaag attacggaag aatacaatct cttgacaggc
    10621 aataatcttt cgtctgagga catggaagca gagcttaaga agttggaagt caatcttgtc
    10681 aatttggcag gtcaacttgc ttctgctcgt cataatttgg ctcagcaact cgaagctgag
    10741 attaaacaag aactgcaaga tctttatatg gaaaaagccc agtttcaggt tcgttttagt
    10801 aagggaaaat tcagtcgtga gggaaatgaa atggttgagt tttatatttc aaccaaccct
    10861 ggagaagact ttaaaccctt ggttaaggtt gcttctggag gggaattatc tcgtctcatg
    10921 ttagccatta agtctgcctt ttcacgtaaa gaaggcaaga ctagcattgt ctttgatgag
    10981 gtggatacgg gagtttcagg tcgtgttgct caagctattg ctcagaaaat tcataaaatt
    11041 ggtcagtatg gtcaggtttt ggctatctcc catttgccac aagtaattgc gattgcagat
    11101 tatcaattct ttattgagaa gattagtaat gaccattcaa cggtttcgac tgttcgtctc
    11161 ttgacagtcg aagagcgagt ggaggaagtt gccaagatgt tggcaggtga tgatgtgaca
    11221 gaagcagccc tgacgcaagc cagagaattg ttgagaaaca gggagaaata agatgacaga
    11281 ttattatgta attggagatg ttcacggaaa agctgggatg ctggaagacc ttcttaaaac
    11341 ctgggatggt cagacccagt tgctctttct aggtgatttg attgacagag gtgaggatag
    11401 tcaccgtgtt cttgaaatgg tcaaggactt ggtggacaat caaggggcta tctgtttgtc
    11461 tggaaaccac gagtatatgt ttttgacttg gctagattac ccagaagaaa gttatgacca
    11521 ttatcgtcgc aatggtggag atacaaccat taactctatc ctaggtcgtc ccttggatgc
    11581 accagttgat ggagtagaag atgccaagcg ggttgccgct gaagcggcag acttggtcga
    11641 attcattcgt caaatgccat ttgtagtaga gacagacaag tatatctttg ttcacgcagg
    11701 tattgatttg accttggacg actggcatga aacaacagat tataaaaaag tatggcttag
    11761 aaaaccattc cacggagctg aaaatcatac tggaaaaacc attgtcttcg gtcatacacc
    11821 ggtctatggt ttgttacagc aagaacgcgg tacatctgag ctttggacta cagaagatgg
    11881 caagattgga atggatggag gagctgttta tggtggtgtc cttcacggga ttgtctttac
    11941 agaccaagga atgacagaac accactttat cgaaaatgac ggctttgtcg ctgaagatta
    12001 gtactcctag cagggtatgg tcttgtcaaa atatcaaaaa caatttataa taaatagata
    12061 ccctgaaagg aagagaatca tgaacttaga agaattgaaa aaacgacagg agaagatccg
    12121 taacttctct attatcgccc atattgacca cggaaaatca actctagcag accgcatttt
    12181 ggaaaaaaca gagacggttt caagtcgtga aatgcaggcc cagcttttgg atagcatgga
    12241 tctagagcgg gaacgtggaa ttactattaa gttgaatgcc atcgagttga attacactgc
    12301 aaaagatggg gaaacttata ttttccactt gattgacaca ccagggcacg ttgactttac
    12361 ctatgaagtt tcacgttcgc tagctgcctg tgagggtgct attttggtgg tcgatgcggc
    12421 tcaaggaatt gaggctcaaa ctcttgccaa cgtttatcta gctttggata atgatttgga
    12481 aatcatgcct atcattaata aaattgacct gccggctgca gatccggagc gcgtgcgtac
    12541 agagattgaa gatgtgattg gtttggatgc cagtgaagca gttttggctt ctgccaaggc
    12601 tggtattggg attgaagaaa tcctcgagca aattgtagaa aaagtaccag caccaacggg
    12661 tgatgtgacg gcgccactta aggccttgat tttcgactct gtttacgatg cttaccgtgg
    12721 ggttatccta caagtgcgtg tcatggacgg agtggtcaaa cctggtgata agattcagct
    12781 catgagcaat agtaagacct ttgatgtggc cgaagtcggt atttttacac caaaagcggt
    12841 tggtcgtgat ttccttgcga ctggtgatgt tggttacatt gcggcgtcta tcaagacggt
    12901 tcaggatact cgtgtgggtg ataccgttac cttggcaacc aatcctgcgg cagaaccatt
    12961 acatggttat aagcagatga atcctatggt ctttgcgggt ctctacccaa tcgaatcaaa
    13021 caagtacaat gacctgcgtg aagcgcttga aaaattgcaa ctgaatgatg ctagtcttca
    13081 gtttgaacca gaaacatctc aggcacttgg atttggtttc cgttgtggat ttcttggact
    13141 tctccatatg gatgttatcc aggaacgttt agagcgtgag ttcaatattg acctcatcat
    13201 gacagctccg tctgttattt acaaagttaa tttgaccgac ggtgagtcta tggatgtgtc
    13261 taacccatct gagtttccag acccaactaa gattgcgacc attgaagagc cttatgtcaa
    13321 ggcgcaaatc atggtaccac aggagttcgt cggagcagta atggagctag ctcagcgtaa
    13381 gcgtggggac tttgtgacta tggactatat tgatgataac cgtgtcaatg ttatctatca
    13441 aattcctctt gctgaaattg tctttgactt ctttgataaa cttaagtctt caacacgtgg
    13501 ttatgcaagc tttgactacg aattgtcaga atatcgccca tctaagctgg tgaaaatgga
    13561 tatccttctc aatggagata aggtggatgc tctcagcttt atcgttcaca aggactttgc
    13621 ctacgaacgt gggaaactca tcgttgataa actcaagaaa atcatccctc gccaacaatt
    13681 tgaagttcca atccaagcgg ctattggaca caagattgtc gctcgtactg atatcaaggc
    13741 ccttcgtaag aacgtacttg ctaaatgtta tggtggtgac gtttctcgta agcgtaaact
    13801 ccttgaaaaa caaaaagctg gtaagaaacg catgaaatcc atcggatcag ttgaagttcc
    13861 gcaagaagcc ttcctcagcg tcttgagtat ggatgaagaa taagttatca gaaatgcctt
    13921 tccttgttca caggaaattt atataagaat caatagtaaa gcaggcttag atggtctgct
    13981 tttttagttt ttatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta
    14041 tgtatggtt
//
LOCUS       DAVLUM010000052        13791 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLUM010000052 DAVLUM010000000
VERSION     DAVLUM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.052"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(60..257)
                     /locus_tag="VYN42_001499"
     CDS             complement(60..257)
                     /locus_tag="VYN42_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1462551.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(332..1108)
                     /locus_tag="VYN42_001500"
     CDS             complement(332..1108)
                     /locus_tag="VYN42_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1462552.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            1230..1976
                     /locus_tag="VYN42_001501"
     CDS             1230..1976
                     /locus_tag="VYN42_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1462553.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1989..2969
                     /locus_tag="VYN42_001502"
     CDS             1989..2969
                     /locus_tag="VYN42_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1462554.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3164..3484
                     /locus_tag="VYN42_001503"
     CDS             3164..3484
                     /locus_tag="VYN42_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1462555.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3530..3838
                     /locus_tag="VYN42_001504"
     CDS             3530..3838
                     /locus_tag="VYN42_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1462556.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3855..5153
                     /locus_tag="VYN42_001505"
     CDS             3855..5153
                     /locus_tag="VYN42_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1462557.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLMISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            5304..7742
                     /locus_tag="VYN42_001506"
     CDS             5304..7742
                     /locus_tag="VYN42_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1462558.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERAHKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPNRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7761..8429
                     /locus_tag="VYN42_001507"
     CDS             7761..8429
                     /locus_tag="VYN42_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1462559.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            8447..9535
                     /locus_tag="VYN42_001508"
     CDS             8447..9535
                     /locus_tag="VYN42_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1462560.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDASVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDSYVNSK"
     gene            9990..12491
                     /locus_tag="VYN42_001509"
     CDS             9990..12491
                     /locus_tag="VYN42_001509"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1462561.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNATNKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            12685..13380
                     /locus_tag="VYN42_001510"
     CDS             12685..13380
                     /locus_tag="VYN42_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462562.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGGYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13392..>13791
                     /locus_tag="VYN42_001511"
     CDS             13392..>13791
                     /locus_tag="VYN42_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462563.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSVLMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTW"
BASE COUNT         4424 a         2143 c         2909 g         4315 t
ORIGIN      
        1 tcacatctta tttcaattca ctatattaga gtaaaattct ctacaaaaag aagaacagcc
       61 tatttgacta ttcttccgag tgatttcaat ttctttgggg aaatatggag atacttttta
      121 aatactttgg caaaatattt atagtctgaa aatccaactt ggtcagagat agcgcttaaa
      181 ggggagttgg gagattcagc catcttatct atagcttgtt tcaggcgata ttgtaagata
      241 tattcattta gagtcatggg gaagtcttct ttgataacct tatatagatg cttgttatct
      301 gcaaatagct agagcatttc aaggaaatga actagaaata acaattaata tggtggttca
      361 gaaatacctt ttgataatca ataagatctt caggatgaag tgcgttgact ccatccattt
      421 catatttccg atttaataaa cgatatttgt tttcaccaaa ttgatgaaaa gggagtagtt
      481 gaacttggtc gatatttaat gagttaaata gagtagcgaa tttttctgca tcctctaaac
      541 tattgttaaa attaggaata actgggattc ttaaaacgat agttttattt tgagaaaaag
      601 cataatgaat gtttttaata atcatttgat taaaaacccc agtcactttt ttatgtttta
      661 tagaattata atgttttagg tctgtgtaga taaaatccac atattgaatt aaatcgataa
      721 atttttcatg atcaacaaag gcagtagttt caatggcagt gtgtatgtga tgttctttag
      781 ctgattttaa gatggcttta gcaaattcaa actgagcaaa tatttcacct cctgataaag
      841 ttaaacctcc accggattct tcgtaaaatt ctttgtcttt taatacctct gtaataattt
      901 cttctacagt cttttcttca ccgactaagg tgaatttctc tcgttgagca tctttcattt
      961 tttcaggttt cattctttga gattcaggat tagaacacca tggacagcgc agaggacatc
     1021 cttttaaaaa aacagttgta cgaatacccg ggccgtcatg aattgaaaag tgttgaatat
     1081 taaaaataat tcctttagat atttccataa gagttcctcc tcttcataag tctatcctat
     1141 cacaaaaacg aaagaaaaac aattacgaac gaaagtttaa tttgttgttt tttgtttttt
     1201 attttggtag aataaaacgg aggtgtaaaa tgaaaagatt ggaacaaatt attaaattag
     1261 tatcagaata tgaaaagatc gacgttaata cattatcgga aaaattaaat gtatcgaaag
     1321 taacgattag aaaagattta gataaattag agtcaaaagg tttattacac agagagcatg
     1381 gatatgctgt attaaatagt ggagatgact taaatgtacg tttgtcaatt aattatgaaa
     1441 ttaagagaaa aattgttcag gaagcagtaa aattggtgtc agataatgaa acaataatga
     1501 tagaatctgg atcgacctgt gctttacttg ctgaggaaat ttgcaagcaa aaaagaaatg
     1561 ttacgattgt aacaaattca ttttttatag caaattttgt gagagcttat gattcatgtc
     1621 gtattattgt tcttggtgga gagtttcaga aggattcaca ggttactgtg ggacctttat
     1681 taaaagaaat gatacagact tttcatgtgc atcaagcttt tgttgggaca gatggttacg
     1741 ataaagagat gggctttaca ggaaaagatt taatgcgcag tgaggtagtt caatatattt
     1801 cagcagcgtc ggataaagtc attgtactaa ctgactcaag taaatttgat aaaaggggta
     1861 cagtaagaag atttgcttta agtcaagtct atgaagtaat aacagacgaa aaactttcta
     1921 aacaaaatat agctacatta gaaaatgctg ggataatggt taaggtagtt tcgtaagagg
     1981 ttaagtgtat gaatcaagat aggaataaac tgctctctaa aattgcttat ctgtattata
     2041 ttgaaaactt aaatcagtca caaatagcag caaaattagg aatttataga acctctatta
     2101 gtagaatgtt aacagaagca aggaatgcag gaattgttaa aattgaaata gagaattttg
     2161 atacaaatat gtttaagttg gaaaattatg taaaagaaaa atatggtctg gaaagtttag
     2221 aaattattcc aaatgaattt gatgataatc caacaatttt atctgaaaga atttctcaag
     2281 ttgcagcagg tgtccttagg aatttaattg atgataatat gaaaattggc ttttcttggg
     2341 ggaaaagttt aagtaattta gtagatttaa ttcacagtaa aagtgtccga aatgttcact
     2401 tctatcctct agcaggtggt cctagtcaca tacacgctaa ataccatgtg aatacactga
     2461 tttatgaaat gtctagaaaa tttcatggag agtgtacatt tatgaatgca acgattgtgc
     2521 aagaaaataa attgttagca gatggtattt tgcaatcaag atattttgaa aatttgaaaa
     2581 atagttggaa agatttagat atagctgtag tcggaattgg tgattttagc aataaaggaa
     2641 aacatcaatg gttagacatg cttacagagg atgactttaa agaattgacc aaagttaaaa
     2701 ctgtaggaga aatttgttgt cgattttttg attcaaaagg taaagaagtc tatgaaaact
     2761 tacaggaaag aacgatagca atctctttgg aagatttaaa aaatattcct caaagtttag
     2821 ctgttgctta cggtgatacg aaagtatctt cgattctttc tgtcttgcgt gctaatttag
     2881 taaatcattt gattacagat aaaaatacaa ttttaaaagt tttggaagaa gatggggatt
     2941 tgacttttag agagattcta ggtgagtgaa aatgatagac tgatcagttt atcgtttttt
     3001 ctttttagtc gattgcacat ttgtgctcat ataaacaaaa atagtttatc tgttgttttt
     3061 ggattgacaa ctttattatg tagttgtatt ctatagttac aaaagaaaat tttaaaattt
     3121 caaatgaaaa aagcttttta catagtgaaa tgaggaggaa tttatggaaa ttattgttcc
     3181 agatcaaatt atcatgggtt taattttata tgctggtgat gcgaaacaac atatttataa
     3241 agcgttagat tacataaaaa atggtacatg tgaacggtgt gaagaagaaa tccagttagc
     3301 tgatgccgcc ttattagaag cccataatct acaaacaaaa ttcttggcac aagaagcgtc
     3361 tggtacaaag acagaaatta cagctctctt tgttcattca caagatcatc tcatgactag
     3421 tatgacggag attaatttaa tcaaagaaat tattagtttg agaaaagaac ttcataaaaa
     3481 ataatactag agtattatca ttgttattaa catagaggag gaaaacataa tggtgaagat
     3541 tggtttgttt tgtgcagcag gtttttctac tggtatgctt gtaaataata tgaaaattgc
     3601 agcgcaagct agtggagttg aggcagaaat agaggcgttt tctcagtcta aattagcgga
     3661 ttatgcgcca aatatagatg ttgcactatt gggtccacaa gttgcttata cattagataa
     3721 atcaaaagaa atttgtgata agtgtgatgt tccgatagct gttattccga tgatggacta
     3781 tggtatgtta gatgggaaaa aagtattaga tttggcccta tctttgatta gtgggtaaga
     3841 aaaggagatt tattatggca aagatggatg ttcagaaaat cattgcaccg atgatgaagt
     3901 ttgtgaatat gcgtggcatt atagctctaa aagatgggat gttagcaatt ttgccattga
     3961 cagtagttgg tagtttattc ttgattatgg gacaattgcc gttcgaagga ttaaataaga
     4021 gcattgctag tgtttttgga gctaattgga cagagccgtt tatgcaagta tattcaggaa
     4081 cttttgctat tatgggtcta atttcttgtt tttcaattgc ctattcttat gctaagaata
     4141 gcggagtaga ggctttacca gctggagttc tatctgtatc tgcattcttt attttgctaa
     4201 gatcatctta tatccctaaa caaggtgagg cgattgggga cgctattagt aaagtttggt
     4261 ttggaggcca aggaattatc ggtgctatca ttataggttt ggtagtagga agtatttata
     4321 ccttctttat aaagagaaaa attgttatta agatgccaga acaagttcca caagctattg
     4381 ccaaacagtt tgaagcaatg attccagcat ttgtaatttt cttactttct atgattgtat
     4441 atattttagc gaagtcattg actaatggcg gaacattcat agaaatgatt tattctgcta
     4501 ttcaagttcc attgcaaggt ttaactggat cttggtatgg tgcaattgga attgcattct
     4561 ttatatcatt tttgtggtgg tttggtgttc atgggcaatc ggtagtaaat ggagtagtga
     4621 cagctctgct tttatctaat cttgatgcta ataaagctat gttagcctct ggtaatctat
     4681 cattagaaaa tggtgcacat attgttactc aacaattttt agattcattt ttaattctat
     4741 caggttcagg gattacgttt ggtcttgtag ttgccatgct ttttgcagca aaatcaaaac
     4801 aataccaagc cttaggaaaa gttgcagctt ttccagcaat atttaacgta aatgagccag
     4861 ttgtatttgg atttccgatt gtcatgaatc cagttatgtt tgtacctttc attcttgttc
     4921 ctgtacttgc agctgtgata gtatatggag ctattgcaac aggtttcatg cagccattct
     4981 caggggtaac attgccttgg agtacaccag ctattctatc aggatttttg gtgggtggat
     5041 ggcaaggtgt tgtgactcag ttattagtat tgatgatatc tacagtggtt tactttccat
     5101 tctttaagat acaagatcgt ttagcttacc aaaatgaaat caaacaatct tagaggtatt
     5161 tgtgtgttac tgttaaactc acacatttgt gctaaaaatt agagagttaa aatttttcta
     5221 gttaaaagct tgaaaatttc tataaaaatc ggtattatat tttcgaaaga aataaaaata
     5281 ttttcgaaag aaaggtggtt gcgatggtaa atacagaagt agcaagaaca acaatcaaga
     5341 cagaatattt tggcagcctt actgaaagga tgaacaaata tcgagaagat gttttaaata
     5401 aaaaacctta tattgatgct gagagagcag ttctagcaac acgcgcctat gaacgataca
     5461 aggaacaacc taatgtccta aaacgtgcat atatgctgaa agaaattttg gaaaatatgt
     5521 ctatctatat tgaagaagaa tctatgattg cgggaaatca agcttcttcc aataaagatg
     5581 ctcctatttt tccggaatat acgctagaat ttgttctcaa tgagttggat ctttttgaaa
     5641 agcgtgatgg agatgttttc tatattacag aagaaacaaa agaacaactt agaagtattg
     5701 ctccgttttg ggaaaataat aatttacgtg ctagagctgg tgccttatta cctgaagaag
     5761 tgtctgttta tatggaaaca ggattcttcg gtatggaagg taagatgaat tctggagatg
     5821 ctcacttagc agttaactat cagaaacttt tgcaatttgg tttaagaggt tttgaagagc
     5881 gggctcataa agcaaaagta gctctagatt taacagatcc agcaagtatt gataaatatc
     5941 atttttacga ctctatattt atcgtaatcg atgctattaa agtatatgca aagcgctttg
     6001 ttgctcttgc taaaagttta gccgaaaatg caaatcctaa ccgtaagaaa gaattacttg
     6061 agattgcaga tatttgctct agagtcccat atgaaccggc aactactttt gcagaagcta
     6121 ttcaatcagt ttggtttatt caatgtattt tacaaattga atctaatggc cactctcttt
     6181 catatggccg ttttgatcaa tatatgtatc catatatgaa ggctgattta gaaagtggta
     6241 aagaaacaga agatagcatt gttgaacgtc tgacaaatct ttggattaag acaattacaa
     6301 ttaataaggt tcgcagtcaa tcacatacat tttcttcagc aggaagtcct ttatatcaaa
     6361 atgttacaat tggtggacag actcgagata agaaggatgc tgttaaccca ttatcttatt
     6421 tggtattaaa atcagttgca caaacccatc taccgcaacc taatctaact gtacgttacc
     6481 atgcaggttt agatgctcgt ttcatgaatg agtgtattga agtgatgaaa cttggttttg
     6541 gtatgcctgc atttaataat gatgagatta ttattccttc ttttattgca aaaggagtat
     6601 tggaagatga tgcttatgat tacagtgcca ttggatgtgt tgaaacggca gttccaggga
     6661 aatggggcta tcgttgcaca ggtatgagtt atatgaactt ccctaaggtt ctacttatca
     6721 cgatgaatga tggaattgat ccggcttcgg gtaaacggtt tgcaccaagc tttggtcatt
     6781 ttaaggatat gaagaacttt tctgaattag aaaatgcttg ggataaaaca ctaagatatt
     6841 tgacacgaat gagtgttatt gttgaaaatt ctattgattt atcattggaa cgagaagttc
     6901 ctgatattct atgttcagca ttgactgatg attgtattgg tcgtggaaaa caccttaaag
     6961 aaggtggagc agtatatgat tatatatcag gattgcaagt tggaattgca aatttgtcgg
     7021 attcattagc tgcaattaaa aaattggtgt ttgaggaaga acgtataagc ccaagtcagc
     7081 tttggcatgc actggaaaca gattatgccg gagaagaagg taaggtcatt caagaaatgt
     7141 tgattcatga tgcacctaag tatggtaatg atgatgatta tgctgacaaa ttggttactg
     7201 ctgcttatga catttatgtt gatgaaattg ctaaatatcc taatacacgt tatggaagag
     7261 gtccaattgg aggaattcgt tattcaggaa catcttctat ctcagccaac gtagggcagg
     7321 gacgtggaac attagcaact ccagatggac gcaacgcggg tacaccgtta gcagagggtt
     7381 gttcaccatc acataatatg gatcaacacg gccctacatc tgttttaaaa tctgtttcaa
     7441 aattaccaac agatgaaatc gtaggtgggg ttctcttaaa tcagaaagta aatcctcaaa
     7501 cgttagccaa agaagaagat aaattaaaac taattgcttt gttacgaaca ttctttaatc
     7561 gtttacatgg gtaccatatt caatacaatg ttgtttccag agagacgctg attgacgctc
     7621 agaaacatcc tgaaaaacac agagacttaa ttgttcgtgt tgcaggatac tctgcattct
     7681 tcaatgttct ttctaaggca acccaagatg acattatagg acgtactgag catactttgt
     7741 aaaataaaga ggttcttttt atggaattta tgcttgacac attaaattta gatgagatta
     7801 aaaagtggtc tgaaattttg ccgctagctg gggtaacttc aaatcccact attgcaaaaa
     7861 gagagggttc tattaatttt tttgaacgaa tcaaagatgt aagagaattg attggctcta
     7921 caccctctat tcatgttcag gtgatttctc aagattttga aggcatctta aaggatgctc
     7981 ataaaattcg aagacaagca ggagatgata tatttatcaa agtacctgtt actccagctg
     8041 gattacgtgc aataaaggcg ctaaaaaaag agggctacca tatcactgca acagctattt
     8101 atacagttat tcagggatta ttagctatcg aagcaggagc ggattaccta gctccatatt
     8161 ataatagaat ggaaaatctg aacattgatt caaattctgt cattcgtcaa ttagctcttg
     8221 ctattgatag acagaactct cctagtaaga ttttagctgc atcctttaaa aatgtagcac
     8281 aagtaaataa tgctttagct gcaggtgcgc atgctgttac agcaggagcg gatgtttttg
     8341 aatcagcttt cgccatgcca tctatccaaa aggcggttga tgatttttct gacgattggt
     8401 ttgttattca aaatagtcgt tccatttaga tagagaggaa atacatatga gaatttttgc
     8461 tagtccttct agatatattc agggggaaaa tgccttgttt gaaaatgcca aatcaatttt
     8521 ggatttggga aattgcccta ttctattatg cgatcagttg gtttatgata ttgttggaaa
     8581 acgatttgaa gattacctac ataggtatgg tttccatatt gttctggcgc tatttaatgg
     8641 tgaagcttct gacaatgaaa tcaatcgagt tgttgccttg gctgagaaag aaaattgtga
     8701 tagtattatc ggtcttggtg ggggaaagac gattgatagc gcaaaagcta ttgcagattt
     8761 gattgaaaag cctgttatta ttgctccaac aattgcatcg accgacgcat ctgtatctgc
     8821 tttatctgtt atttatacag atgaaggtgc atttgatcat tatctatttt attctaaaaa
     8881 tccagattta gttttggttg atacaaaagt tatttcacaa gcccctaagc gtttattagc
     8941 gtctggtatt gcagatggtt tagcaacttg ggttgaggcg cgtgcggtta tgcaggcaaa
     9001 tggaaaaact atgttgggac aacagcaaac attggctgga gttgcaattg cgaagaaatg
     9061 tgaagaaacg ctgtttgcag atggtttaca ggctatggca gcttgtgaag ctaaagtggt
     9121 gacaccagca ttagaaaata ttgttgaagc taatacttta ttgagtggtc taggttttga
     9181 aagtggagga ttagctgcgg cgcatgcaat tcataatggt tttactgcat tgacaggtga
     9241 cattcatcat ttaacacatg gtgaaaaagt agcttatgga actttagtac aactattatt
     9301 ggaaaataga cctaaagaag aacttgataa gtatattgag ttttacaaaa aaattggtat
     9361 gccaacaact ctaaaagaaa tgcatttgga tcaagttgga tatgatgatt taataaaagt
     9421 tggtaaacaa gcaactatgg agggtgagac aattcatcag atgccgttta agatttcgcc
     9481 ttcagatgtt gctcaagcta ttatcgctgt agattcctat gtaaattcaa aataaacaat
     9541 aaggactact gttttccaaa tggtagtctt ttattgatcc tcgtattgaa ttctatagca
     9601 gattgaaata agatgagaac aaatcgattg ggaaagtaaa attaatttct aacaatgttt
     9661 tagcaattgt ttcgtactat ttcagattca gtccactata cgttcttcat aaatcaaaaa
     9721 gcgacatagg ttgtcggcta tttattgtga atacattaat tagcattcca gttttatctt
     9781 cggtctaaaa taagtatttt gtgctatacg agataagctt cttgacttac tccttgattt
     9841 actgcataac aatgggataa aaagtgggag atagagcaat tcatagtcat caaaattaat
     9901 gagatacagt atacagtttt tcctttaaac acatttcaaa ttccctcaaa aatggtataa
     9961 tagtaacatc acaaaattgg agagagacca tgagttttta caatcataaa gaaattgagc
    10021 ctaagtggca gggctactgg gcagaacatc atacatttaa gacaggaaca gatgcatcaa
    10081 aacctaagtt ttatgcgctt gatatgttcc cttatccgtc tggagctggt ctgcacgtag
    10141 gacacccaga aggttatact gcaaccgata tcctcagtcg ttacaaacgt gcgcaaggct
    10201 acaatgtcct tcacccaatg ggttgggatg cttttggttt gcctgcagag caatacgcta
    10261 tggatactgg taatgaccca gcagaattta cagcggaaaa cattgccaac ttcaaacgtc
    10321 aaattaatgc gcttggattt tcttatgact gggatcgtga agtcaacaca acagatccaa
    10381 actactacaa gtggactcaa tggattttca ccaagcttta cgaaaaaggc ttggcctatg
    10441 aagctgaagt gccagtaaac tgggttgagg aattgggaac tgccattgcc aatgaagaag
    10501 tgcttcctga cggaacttct gagcgtggag gctatccagt tgtccgcaaa ccaatgcgcc
    10561 aatggatgct caaaatcacg gcttacgcag agcgcttgct caatgactta gatgaactag
    10621 attggtcaga gtctatcaag gatatgcaac gcaactggat tggtaaatca actggtgcca
    10681 atgtaacttt caaagtaaaa ggaacagaca aggaatttac agtctttact actcgtccgg
    10741 acacactttt cggtgcgact ttcactgtct tggctcctga acatgaatta gtagacgcta
    10801 tcacaagttc agagcaagca gaagctgtag cagactataa acaccaagcc agccttaagt
    10861 ctgacttggc tcgtacagac cttgctaaag aaaaaacagg ggtttggact ggtgcttatg
    10921 ccatcaaccc tgtcaatggt aaggaaatgc caatctggat tgcagactat gtccttgcta
    10981 gttatggaac aggtgcggtt atggctgtgc ctgcccacga ccaacgtgac tgggaatttg
    11041 ccaaacaatt tgaccttcca atcgtcgaag tacttgaagg tggaaatgtc gaagaagctg
    11101 cctacacaga ggatggcctg catgtcaatt cagacttcct agatggactc aacaaagaag
    11161 acgctattgc caagattgtg gcttggttgg aagaaaaagg ctgtggtcag gagaaggtta
    11221 cctaccgtct ccgcgactgg ctctttagcc gtcaacgtta ctggggtgag ccaattccaa
    11281 tcattcattg ggaagatgga acttcaacag ctgttcctga aactgaattg ccgcttgtct
    11341 tgcctgtaac caaggatatc cgtccttcag gtactggtga aagtccacta gctaacttga
    11401 cagattggct tgaagtgact cgtgaagatg gtgtcaaagg tcgtcgtgaa accaacacta
    11461 tgccacaatg ggctggttca agctggtact acctccgcta tattgacccg cacaatactg
    11521 agaaattggc tgatgaggac ctcctcaaac aatggttgcc agtagatatc tacgtgggtg
    11581 gtgcggaaca tgctgtactt cacttgcttt atgctcgttt ctggcataaa ttcctctatg
    11641 acctcggtgt tgttccgact aaggaaccat tccaaaaact ctttaaccaa gggatgattt
    11701 tgggaacaag ctaccgtgac caccgtggtg ctcttgtggc aaccgacaag gttgaaaaac
    11761 gtgatggttc cttcttccat gtagaaacag gggaagagtt ggagcaagcg ccagccaaga
    11821 tgtctaaatc gctcaagaac gttgttaacc cagacgatgt ggtggaacaa tacggtgccg
    11881 atacccttcg tgtttatgaa atgtttatgg gaccactcga tgcttcgatt gcttggtcag
    11941 aagaaggttt ggaaggaagc cgtaagttcc ttgaccgagt ttaccgtttg attacaagta
    12001 aagaaatcct tgcggaaaac aatggtgctc ttgacaaggt ttacaacgaa acagtcaaag
    12061 ctgttactga gcaaattgag tctctcaaat tcaacacagc tattgcccaa cttatggtct
    12121 ttgtcaatgc tactaacaag gaagataagc tttatgttga ctatgccaaa ggctttattc
    12181 aattgattgc accatttgca cctcacttgg cagaagaact ctggcaaaca gtcgcagaaa
    12241 caggtgagtc aatctcttat gtagcttggc caacttggga cgaaagtaaa ctggttgaag
    12301 acgaaatcga aatcgttgtc caaatcaaag gtaaagtccg tgccaaactc atggtcgcta
    12361 aagacctatc acgtgaagaa ttgcaagaaa ttgctctagc ggatgaaaaa gtcaaagcag
    12421 aaattgacgg taaggaaatc gtgaaagtga ttagtgtacc aaataaattg gttaatattg
    12481 ttgtaaaata accaatttat ttgctgattt ccaacctcaa acagtttccc aaactgtttg
    12541 agccaactaa actcgttaat atcgttgtga aataaggtag gaatccttca gagtagaatc
    12601 tggaggattt tttgaatctt cttatgaaag tatggtatac tatgggcaac tataaagttt
    12661 gaaaagtgaa aaaaggagaa agctatgcca gtaaatgaat atggtcaaat gattggggag
    12721 tcaatggaag gttatacacc aggtgaactg ccttctattg atttcttaga agggggttat
    12781 gctaggatag aggctctttc agtggaaaag catgcggagg atttgctagc tgtttatggg
    12841 cctgatacgc ctcaggagat gtggacctac ctttttcagg agccagtagc agatatgggg
    12901 gagctggtta gccttttaca tcagatgttg gctcgtaagg accgttttta ctatgcaatc
    12961 atagacaagg cgactggtaa ggctttggga tctttttctc tcatgcgcat tgaccagaat
    13021 aaccgagtaa tagaagtggg agctgtcact ttttctccag agctaagggg tacacggata
    13081 ggaactgaag ctcagtatct cctagctcgc tatgtttttg aggagctaaa ctatcgtcgc
    13141 tacgagtgga aatgcgatgc cttaaatctg ccatccagac gagctgcgga gcgtttgagc
    13201 tttatttatg aaggaacctt ccgtcaggca gtggtttata agggacgtac gagagatacg
    13261 gattggttgt ctatgattga taaggactgg cctcaagtca aagatcgttt ggaaacatgg
    13321 ttgcgtcctg aaaattttga taaaaatgga cagcagtaca agagcttgag agaactttaa
    13381 gaggtgttga gatgattact attaaaaagc aagaaattgt caagctagag gatgttttac
    13441 atctctatca ggctgtcggt tggacaaatt atacccatca accagagatg ctggagcagg
    13501 ccttatctca ttcattagta atttatctgg cacttgatgg tgatgctgtg gtgggcttga
    13561 ttcgtttggt tggagatgga ttctcatcag tattggttca ggatttaatc gttttaccaa
    13621 tctatcagcg tcaaggaatt ggtagtgtct tgatgaaaga ggctttagag gattacaaag
    13681 atgcctatca agtccagctg gtgacagaag agacagaaag aaccttgggc ttctatcgtt
    13741 ctatgggctt tgaaatctta tccacctata attgtatagg gatgacttgg a
//
LOCUS       DAVLUM010000053        13549 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLUM010000053 DAVLUM010000000
VERSION     DAVLUM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.053"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            83..547
                     /locus_tag="VYN42_001512"
     CDS             83..547
                     /locus_tag="VYN42_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1462564.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            704..1129
                     /gene="lacA"
                     /locus_tag="VYN42_001513"
     CDS             704..1129
                     /gene="lacA"
                     /locus_tag="VYN42_001513"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1462565.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1160..1675
                     /gene="lacB"
                     /locus_tag="VYN42_001514"
     CDS             1160..1675
                     /gene="lacB"
                     /locus_tag="VYN42_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1462566.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1686..2615
                     /locus_tag="VYN42_001515"
     CDS             1686..2615
                     /locus_tag="VYN42_001515"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1462567.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2617..3597
                     /gene="lacD"
                     /locus_tag="VYN42_001516"
     CDS             2617..3597
                     /gene="lacD"
                     /locus_tag="VYN42_001516"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1462568.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            3831..4667
                     /locus_tag="VYN42_001517"
     CDS             3831..4667
                     /locus_tag="VYN42_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1462569.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4703..5020
                     /locus_tag="VYN42_001518"
     CDS             4703..5020
                     /locus_tag="VYN42_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1462570.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5020..6711
                     /locus_tag="VYN42_001519"
     CDS             5020..6711
                     /locus_tag="VYN42_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1462571.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6926..8332
                     /gene="lacG"
                     /locus_tag="VYN42_001520"
     CDS             6926..8332
                     /gene="lacG"
                     /locus_tag="VYN42_001520"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1462572.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8375..8560
                     /locus_tag="VYN42_001521"
     CDS             8375..8560
                     /locus_tag="VYN42_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1462573.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWDTISFDSDFMPFQQS"
     gene            complement(8839..9600)
                     /locus_tag="VYN42_001522"
     CDS             complement(8839..9600)
                     /locus_tag="VYN42_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1462574.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9888..10850)
                     /gene="nrdF"
                     /locus_tag="VYN42_001523"
     CDS             complement(9888..10850)
                     /gene="nrdF"
                     /locus_tag="VYN42_001523"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1462575.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11038..13197)
                     /gene="nrdE"
                     /locus_tag="VYN42_001524"
     CDS             complement(11038..13197)
                     /gene="nrdE"
                     /locus_tag="VYN42_001524"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1462576.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13278..13496)
                     /gene="nrdH"
                     /locus_tag="VYN42_001525"
     CDS             complement(13278..13496)
                     /gene="nrdH"
                     /locus_tag="VYN42_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1462577.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
BASE COUNT         4162 a         2447 c         2788 g         4152 t
ORIGIN      
        1 tgctggcatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ataaagaaac
       61 tagcaaggtc aggccttact ttattggtgg acatccagga tttaattgtc ctctacttga
      121 tgatgaagtc tatgaagatt attatctaga gtttgagaaa gaagagactt gctctgttcc
      181 acgtcctttc ccagaaacag gtatgttgga tttccaagat agaagtccat ggctagaggg
      241 acaaaaagaa atagatctta gttatgatct tttcagcaaa gatgcagtga ctttggatga
      301 attgcaatct cgaacaattg cccttcgttc tcttaaacat gataggggat tgaaagtgca
      361 ttttgcagaa tttccaaacc tcatcatctg gtcaactttg aacaagggac ctttcattac
      421 ctttgaacca tggtctggct tgtcaacatt ccttgaagaa ggagatcatt tagaagataa
      481 gaagaatgtt tgtctcttag aagccaatca ggttgaagaa ttagggtttg agatagaagt
      541 tttataaaaa agtaaaaaat aaataacaaa aacaaacaca aactgttgac ttcttcaaac
      601 aatagtagta tattatgttt gtgaggacta attgactgtt ttttaaagac agccaataca
      661 ctgctggaat ccagcataga aaaaataaaa aggagtatac aatatgtcta ttgttatcgg
      721 tgcagatgct gcaggtttga gattgaaaga agttgtgaaa gacttcttag aaaaagaaaa
      781 cttccacctt gtggatgtta cagctgaagg tcaagacttt gttgatgtga ctctcgctgt
      841 tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc gtgattgatg cttatggagc
      901 tggtccattt atggttgcaa ctaagatcaa aggaatggtt gctgcagaag tttctgatga
      961 acgttcagct tatatgactc gtggccacaa caactcacgt atgatcacta tgggtgcaca
     1021 acttgttggt gatgaattgg ctaaaaacat cgctaaagga tttgttaatg gtaaatacga
     1081 cggtggtcgt caccaaatcc gggttgacat gttgaacaaa atgggctaat tagattatag
     1141 taagaaaggt aagttaaaaa tgagaattgc aattggatgt gaccacatcg taacagatga
     1201 aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat gaagtcattg actttggtac
     1261 atatgaccat acacgtactc actacccaat ctttggtaaa aaagtagggg aagctgtaac
     1321 tagcggtcaa gctgatcttg gagtatgtat ctgtggtact ggtgttggta tcaacaacgc
     1381 tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt gatatgacaa cagcccttta
     1441 tgctaaagaa caattgaacg ctaacgttat tggttttggt ggtaaaatta ctggtgaatt
     1501 gcttatgtgt gatatcatcg aagctttcat ccatgctgaa tacaaaccaa ctgaagaaaa
     1561 caaaaaattg attgcgaaaa ttgaacatgt tgaaagtcac aatgctcaac aaacagacgc
     1621 aaacttcttt acagaattcc ttgagaaatg ggatcgtgga gaataccacg actaagaggt
     1681 gacctatgat tttaacagtc acaatgaacc catccatcga tatttcctat cccttggatg
     1741 agttgaagat tgatactgtc aatcgtgtgg tggatgtaac caaaacggct ggtggtaagg
     1801 gactcaatgt tacccgagta ctttcagaat ttggcgattc tgttcttgct actggtttag
     1861 tgggtggcaa acttggtgag tttttggttg aacatatcga taatcaagta aagaaagatt
     1921 tcttctcaat taagggagaa actcgtaact gtatcgctat tctccacgga gacaaccaaa
     1981 cagaagttct tgaaaaaggt cctgaagtat tggaacagga aggtcaagag tttttggaac
     2041 atttcaaaaa actcttggag tcagttgaag tagtagccat ctcaggtagt ctgccagctg
     2101 gccttccagt tgattactat gcgagcttgg tagaacttgc taatcaagct ggcaagcctg
     2161 tagtcttgga ctgctcaggt gcagcacttc aggctgttct tgaatcaccc cataaaccaa
     2221 cagtcatcaa accaaataat gaagaattgt ctcagcttct tggaagagaa gtttctgagg
     2281 atttggatga attaaaagaa gtacttcaag aacctttgtt tgcagggatt gaatggatta
     2341 tcgtttcact tggtgccaac ggtacttttg ccaaacatgg tgacactttc tacaaggtag
     2401 atattcctag aattcaggtg gtaaatcctg ttggatctgg agactctact gtggcaggaa
     2461 tttcttcagg acttcttcac aaagaatcgg atgcagaatt actcatcaag gcaaatgtcc
     2521 ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt caacatggcc aactatcaag
     2581 ctctatatga tcaattaata gtaaaagagg tataaaatgg ctttaacaga acaaaaacgt
     2641 gtacgcttag aaaaactttc tgatgaaaat ggtatcatct cagctcttgc atttgaccaa
     2701 cgtggtgctt tgaaacgcct catggctcaa caccaaacag aagaaccaac tgtggcccaa
     2761 atggaagaac ttaaagtctt ggtagcagat gaattgacta aatatgcttc atctatgctt
     2821 cttgaccctg agtatggact tccagcaact aaagctcttg atgaaaaagc tggtcttctc
     2881 cttgcttatg aaaaaacagg ttatgacaca acaagcacaa aacgcttgcc agactgcttg
     2941 gatgtttggt ctgcaaaacg tattaaagaa gaaggtgcag atgcagttaa attcttgctt
     3001 tactatgatg tagatagctc agacgaactc aatcaagaaa aacaagccta catcgaacgc
     3061 atcggttctg agtgtgtggc tgaagatatc ccattcttcc ttgaaatcct tgcttacgat
     3121 gaaaaaattg cggatgcagg ttctgtagaa tacgctaaag taaaaccaca caaagttatc
     3181 ggcgctatga aagtcttttc agacccacgc tttaacattg atgttttgaa agttgaagtt
     3241 cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg aagtagttta tacacgtgaa
     3301 gaagcagcag ccttcttcaa agcgcaagat gaagcaacga acttgccata catctacttg
     3361 agtgctggtg tatcagctaa actcttccaa gatactcttg tatttgctca tgaatcaggt
     3421 gcaaacttta acggagttct ttgtggccgt gctacatggg caggatcagt tgaagcttac
     3481 atcaaagatg gtgaagcagc agctcgcgaa tggcttcgca caactggatt tgaaaacatt
     3541 gacgaactca acaaagttct tcaaagaaca gcaacttcat ggaaagaacg cgtgtaagaa
     3601 agtcctccta gtttaggaac atgaatctaa aaaaatttaa aaaaagttgt atgtaaaggt
     3661 ttacaaaata acttacttgt gctatactta aatcacaagt taatacaagg tgagtgttac
     3721 taagtaatat taggcatgat cacaggtgaa ttagaaatca gctgattttc tagttcattt
     3781 gtggtcattt tttgtactca tataccttta aaatataaaa ggaggttgac atgtatcgaa
     3841 ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa tgataaggga gaagaggtga
     3901 ttgtaattgg taaggggatt gcattcggaa agaagaaggg ggatttgatt gctgaaaatc
     3961 aggttgagaa aatctttcgg atgaagaccg aagagtccag agaaaacttt atggctcttc
     4021 tcaaagatgt tccgcttgat tttatcacag tgacctatga aatcattgat aagctatcaa
     4081 agaaatatca ttatccgatt caagagtatc tctatgtaac cttgacagat catatttact
     4141 gttcttatca agctctaact caaggaaggt acaaggatag taatctgcca gatatttccg
     4201 ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt tgaaatttac cgtcagaagc
     4261 tagcagatca ttttcctgag gacgaaatta ttcggattgc ttatcatttc attaatgctg
     4321 aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa gaggaaagaa attctcagga
     4381 atgttgaaga agttttaacg gactatgcaa ttcaacgaac taaaaagaat aaccatttct
     4441 atgatcgctt tatgatccat ttgaattatt tcttggatta tttagacaga tctagagatg
     4501 ataaccaatc acttctggat atggaagatc atattaaaca atcctatcca aaagccttcg
     4561 agattggttc caagatctat gatgtgatta cgcaacatac gggtcttgat ttgtataaaa
     4621 gtgaacgagt ttatctagtt ctacatatcc aacgtttatt gtcataaaaa tttatttaaa
     4681 actatataag gagaattcta tcatgaatag agaagaagta acattgttag gttttgaaat
     4741 cgtagcctat gctggcgatg ctcgttcaaa actattggaa gccttgaagg ctgctgaagc
     4801 tggtgatttt gaaaaagcgg acgctctggt agaggaagct ggtagctgta ttgcagaggc
     4861 tcaccacgcg caaacaagtc tattgactaa ggaagcttct ggtgaggact tagcgtatag
     4921 tgtgaccatg atgcatggtc aagatcactt gatgacaact atcttgttaa aggatttgat
     4981 gcaccatttg atcgaactct acaagagagg agttaaataa tgaacaaact aattgcattt
     5041 atcgagaaag gaaagccttt ctttgagaaa ctatctcgta atatctatct tcgtgctatt
     5101 cgtgatggtt tcattgcagg tatgcctgtt attctcttct caagtatctt tatcttgatt
     5161 gcctttgtac caaactcatg gggctttaaa tggtctgatg aagttgtagc ctttctgatg
     5221 aaaccttata gctattctat gggtattctg gctctcttgg tagctggtac aacagctaag
     5281 tcattgaccg actcagtaaa ccgtagcatg gagaaaacca atcaaatcaa ctatatgtca
     5341 acgctgttag cagcgattgt tggtttgttg atgttggcag ctgatcctat cgaaaatggt
     5401 ctagctactg gattcttggg gacaaaaggt ttgctttcag ccttccttgc tgcctttgtt
     5461 actgtagcca tctataaggt ttgtgttaag aacaacgtca ctattcgtat gcctgacgaa
     5521 gttccaccaa atatctcaca agtctttaaa gatgtgattc cattcactct atctgttgtt
     5581 tctctttatg ctcttgactt attagcacgt cattttgttg gttctagtgt ggcagaatca
     5641 atcggtaaat tcttcgcacc actcttctca gcagcagacg gataccttgg tattaccatt
     5701 atctttggtg cctttgcctt cttctggttt gttgggattc atggtccatc tatcgttgaa
     5761 ccagctatcg cagctattac ctatgccaat gccgaagtca acttgaacct tctccaacaa
     5821 ggtatgcacg ctgacaagat tcttacttct ggtacacaaa tgtttatcgt taccatgggt
     5881 ggtactggtg cgacactggt tgttccattc atgttcatgt ggttaacaaa atcaaaacgt
     5941 aaccgtgcaa tcggacgtgc ttcagtagtt cctaccttct tcggtgtaaa tgaaccaatc
     6001 ttgtttggtg cacctcttgt tttgaatcca atcttcttca ttccatttat ctttgctcca
     6061 attgcaaacg tatggatttt caaattcttt attgaaacac ttggaatgaa ttcatttact
     6121 gctaatctac catggacaac cccagctcca ctaggtctag ttcttggtac gaacttccaa
     6181 gttctatcat tcattcttgc tgctcttcta atcgtggttg acgttgtcat ttactatcca
     6241 ttccttaaag tttatgacga acaaattctt gaagaagaac gttcaggtaa gtctaatgat
     6301 gaattgaaag aaaaagttgc tgcaaacttc aacactgcaa aagcggatgc tattcttgaa
     6361 aaagcgggtg tcgatgcagc acaaaatacc atcactgaag aaacaaatgt cctcgttctc
     6421 tgtgctggtg gaggtacaag tggactcctt gcaaatgctt tgaataaggc agcagcagaa
     6481 tacaatgtcc ctgtgaaagc agcagcaggc ggctatggtg ctcaccgtga aatgttacca
     6541 gagtttaatc tagttatcct tgcccctcaa gttgcttcaa actttgaaga tatgaaggca
     6601 gaaacagata agctcggtat taaacttgct aagacagaag gcgctcaata catcaaatta
     6661 actcgtgatg gaaaaggtgc cctagcattc gtacaagagc aattcgatta aggctaggaa
     6721 ctgtgaaaca gtctcccatc gttacggaaa tcgctatggc gaatttccta atcgccttat
     6781 taattcgtcg gtaaaaagat atcgttttta cctcctcatg tcacaattca gtgacttggt
     6841 acaagaagtg agatggagaa gcatggctca ctgactcctc tcctctcact tttactttat
     6901 ttaaatcaag aaataggtga aaaaaatgac aaaaacactt ccaaaagact ttatttttgg
     6961 tggcgcaaca gctgcttatc aagcagaagg tgctacacat actgatggaa aaggaccagt
     7021 tgcttgggat aaatatcttg aggataacta ctggtacact gccgaaccag ctagtgattt
     7081 ttacaatcga tatccagttg acctcaagct agcagaagag tatggtgtca atggcattcg
     7141 aatttctatt gcctggtcac gtattttccc gactggttac ggccaagtaa atgctaaagg
     7201 tgttgagttt tatcataatt tatttgcaga gtgtcacaaa cgtcatgttg agccttttgt
     7261 aactcttcat cactttgaca cgccagaagc tctccactca aatggagact tcttaaaccg
     7321 tgaaaatatc gaacattttg tagactacgc tgccttctgt tttgaagaat ttccagaagt
     7381 aaactattgg acaaccttta atgaaattgg accaatcggt gatggtcaat atttggttgg
     7441 gaaattccct ccaggtatcc agtacgacct tgccaaagtc tttcaatcac accacaatat
     7501 gatggtgtct catgcatgcg cggtaaaatt gtacaaagag aaaggctata aaggggaaat
     7561 tggtgttgtt cacgccctgc ctactaaata tcctctagat cctgaaaatc cagcagatgt
     7621 tcgtgcagca gagttggaag atatcatcca caataaattc atcttagacg caacttatct
     7681 aggtcgctat tcagctgaaa ccatggaagg tgtcaaccat atcttatcag tcaatggtgg
     7741 tagtttggat cttcgtgaag aagattttac agcattagaa gctgcaaaag acttgaatga
     7801 tttcctagga atcaactact atatgagtga ctggatggaa gcctttgatg gagaaactga
     7861 aattatccat aatggtaaag gtgaaaaagg aagctctaag tatcaaatca aaggtattgg
     7921 tcgtcgtgta gctcctgact atgtatcacg cacggattgg gattggatta tctaccctca
     7981 aggtttgtat gaccaaatca tgcgtgtgaa gaaagattat cctaactaca agaaaattta
     8041 tatcactgaa aatggtctcg gctataaaga tgagttcgtt gataacactg tttacgatga
     8101 tggtcgtatt gattacgtga aacaacactt ggagatcttg tctgatgcga ttgcagatgg
     8161 agctaatgta aaaggttact tcatttggtc attaatggat gtcttctcat ggtcaaacgg
     8221 ttatgagaaa cgttatggtc tcttctacgt agattttgaa actcaagaac gttatcctaa
     8281 gaaatcagct cactggtaca agaaagtagc ggaaactcag attatagact agtagaatta
     8341 gtcattagat atagaatttt agtgagtcaa aaagatgttc aaagatttta tccaatctat
     8401 ttatgaaaaa gtttatatta taaatttcga aaaatgctct caaataccgt gtttgacgag
     8461 tgaagaattg aaaagtcttg gaaaatggta tgtctcgact ggtaaagaat gggatactat
     8521 ctcctttgat tcagatttta tgccgtttca acaatcgtaa ccaatttctc aaaaaagtta
     8581 aatcttatat ttagtactct gtaaaactct tatctaatca cgttgcttat actcaatgaa
     8641 aatcaaagag caactttaaa ctaggaagcg agtcgcagat ttctcaatgc atagctttga
     8701 ggaattgggc aaaaagtctt tgatatagaa aaacgcatag tatcaggtgt tgaaacacct
     8761 gatactatgc gttttattgt gggaagattt actttttttc ttctgaaatt gagttgttac
     8821 ccaggctctt tcagtttatt aaggcttgat gactttaatg tgtttagata gcttaaaaag
     8881 gattgaatca cttagtttag aatctgaaac aatagtatca agatttgata cattataaaa
     8941 agtataaaaa tcaaacttat tgaacttgct atgatctgcg agtaaatatt ttttattaga
     9001 attatttaaa gcgatgcgtt gagcctctcc ctcttcctcg ctaaaagtag ctagagctcc
     9061 gttttgaata ccattacagc taacgaaagc tttagaaaat tggagattag agagattttg
     9121 tagggtcaat gtaccaacaa aagcacctgt aatatcgcga taatttccac ctattaaaat
     9181 caaatctgtt aattttcgtt cgcttaaaat cagaaaaaca ggtagactgt tggttacgac
     9241 gcggatattg tcaataggca actcacgcgc aaaaaactct aatgttgttc ctggtccaat
     9301 gaaaatagtt tctctttctt ctactagact gcctgcaaaa tgggctattt cttgtttttc
     9361 tgccgtttgg agggcttgtt tttcaatatt tgatcgctca ttagtcaaaa gggagttggt
     9421 tcgaagtttt tcagctccac catgcacacg aatcagcaaa tctttatcag ctaattcctg
     9481 taaatagcgc cttgcagtca tatctgaaac ggctatttcg tccataatct gtttaactgt
     9541 tatggttcct ttactattta ctatctctaa aattttggct aatttttctt gtttgagcat
     9601 attatcacct cgtttcctac tactatctta ccataaacaa actcatcatt caaatacaaa
     9661 aacaacaaaa taaaacaaaa acaaaaatat cgaggtttat tttcaaaact ttcgatattt
     9721 ttattaagtt attattttgt tgtttctagt ttactttttg atggttaaga gtggtggaga
     9781 attatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gtacttgagt
     9841 acggcaaggc gaagctgacg tggtttgaat ttgattttcg aagagtatta gtccaaaccg
     9901 tagttgtagt catcatcttg catggcttca acttcgccaa gaaggtaacc atttccgact
     9961 tgagagaaga agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg
    10021 acatcttcag ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg
    10081 gcattgtagc gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc
    10141 tctgtgtagc cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg
    10201 agtttttctt gctcttcttc aggtaattca ttgaaaccaa gttggaattt gtaaccaatg
    10261 taggttccgt gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggca
    10321 agtttgttgt taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt
    10381 tcgaggaaga cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg
    10441 acaatctcag ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca
    10501 atctcagcct tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat
    10561 tccataaatt ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga
    10621 agggcttgaa ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact
    10681 tttccgacca agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat
    10741 aagggaatac gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg
    10801 atgacatctt cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc
    10861 tttctgtgtt tagtattgcg aactcacaat tatttctact ttaccataat tctataggag
    10921 tatcgcacaa aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat
    10981 agtagatttg attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta
    11041 aatcacacag ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg
    11101 gacgtagtag atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc
    11161 acgtgtcgtt tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg
    11221 catgaagagg gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc
    11281 gatgacttta cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga
    11341 caagccagca gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg
    11401 ttgcgtaatc gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg
    11461 cgctacagca aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc
    11521 agcccaatca gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga
    11581 tgttggaaca aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga
    11641 tttttcaaag ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa
    11701 ggtccagtag ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc
    11761 atattcaatg agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt
    11821 gtgggcttgg ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt
    11881 aacgaaagta agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat
    11941 catgttaacc acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa
    12001 ttcttgagca tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt
    12061 actcatgata atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac
    12121 ataaggatag ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt
    12181 gatttttgtc ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc
    12241 gatgtaattg aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat
    12301 ttcttcattt ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag
    12361 agtcttgaca cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat
    12421 atctgggtga aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt
    12481 ggagtaagag aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc
    12541 ttcatagcct ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc
    12601 accaccaata cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc
    12661 atccgtcact tggattagga aacaagatac caactcccca cgacgagcac gtccagcatt
    12721 caagaaggaa ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat
    12781 tgcaacagct tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat
    12841 attttcaaga tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata
    12901 agctgccatg aatgacttga attggaagtt ttggtctttg ataaattgag ccaattcttc
    12961 caagaactct ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag
    13021 gtaattgatt ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt
    13081 aaagaaagca tccaaggctt ccttatcttt atgaagcatg atttgtccat taacaggacg
    13141 gttaatttcg ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa
    13201 atttccctta tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc
    13261 tggatgatgt actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag
    13321 acttcagttg gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg
    13381 acgtactcag gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag
    13441 aaacgcttgg tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg
    13501 taactcctct tcaaaattta atactatctt agtatatcag aaaataaaa
//
LOCUS       DAVLUM010000054        13153 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLUM010000054 DAVLUM010000000
VERSION     DAVLUM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.054"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..1072
                     /gene="dnaN"
                     /locus_tag="VYN42_001526"
     CDS             <1..1072
                     /gene="dnaN"
                     /locus_tag="VYN42_001526"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1462578.1"
                     /translation="SSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAG
                     LLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYP
                     RIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDS
                     HRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIEAVEIFFANNQILFRSENISF
                     YTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGV
                     VSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRP
                     FTLVPADTDEDFMQLITPVRTN"
     gene            1137..1331
                     /locus_tag="VYN42_001527"
     CDS             1137..1331
                     /locus_tag="VYN42_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1462579.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1415..2530
                     /gene="ychF"
                     /locus_tag="VYN42_001528"
     CDS             1415..2530
                     /gene="ychF"
                     /locus_tag="VYN42_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1462580.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2601..3170
                     /locus_tag="VYN42_001529"
     CDS             2601..3170
                     /locus_tag="VYN42_001529"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1462581.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            3171..6680
                     /gene="mfd"
                     /locus_tag="VYN42_001530"
     CDS             3171..6680
                     /gene="mfd"
                     /locus_tag="VYN42_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1462582.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6738..7004
                     /locus_tag="VYN42_001531"
     CDS             6738..7004
                     /locus_tag="VYN42_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1462583.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            6997..7365
                     /locus_tag="VYN42_001532"
     CDS             6997..7365
                     /locus_tag="VYN42_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1462584.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7485..8753
                     /locus_tag="VYN42_001533"
     CDS             7485..8753
                     /locus_tag="VYN42_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1462585.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLLQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8750..10027
                     /gene="tilS"
                     /locus_tag="VYN42_001534"
     CDS             8750..10027
                     /gene="tilS"
                     /locus_tag="VYN42_001534"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1462586.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10031..10573
                     /gene="hpt"
                     /locus_tag="VYN42_001535"
     CDS             10031..10573
                     /gene="hpt"
                     /locus_tag="VYN42_001535"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1462587.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10589..12547
                     /gene="ftsH"
                     /locus_tag="VYN42_001536"
     CDS             10589..12547
                     /gene="ftsH"
                     /locus_tag="VYN42_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1462588.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            12669..13148
                     /locus_tag="VYN42_001537"
     CDS             12669..13148
                     /locus_tag="VYN42_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1462589.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT         4530 a         1969 c         2709 g         3945 t
ORIGIN      
        1 tagttctaaa aatgccattc ctattttatc aacagtaaaa attgacgtga ccaatgaagg
       61 tattacttta attggttcaa atggtcaaat ttcaattgaa aattttattt ctcaaaaaaa
      121 tgaagatgct ggtttgttaa ttacttcttt aggttcgatc cttcttgaag cttctttctt
      181 tatcaatgta gtatctagtt tacctgatgt aactcttgat tttaaagaaa ttgaacaaaa
      241 tcaaattgtt ttaaccagtg gcaaatcaga aattacccta aaaggaaaag atagcgaaca
      301 atatccacga atccaagaaa tttcagcaag cactccttta atacttgaaa caaaattact
      361 caagaaaatt attaatgaaa cagcctttgc tgcaagtaca caagagagtc gtccgatttt
      421 aacaggtgtc cacttcgtat tgagtcaaca caaagagtta aaaacagttg caacagactc
      481 tcatcgccta agccagaaaa aattgactct tgaaaaaaat agtgatgatt ttgatgtcgt
      541 aattcctagc cgttctctac gcgaattttc agcggtattt acagatgata tcgaagctgt
      601 agagattttc tttgccaata accaaatcct ctttagaagc gaaaatatta gcttctatac
      661 tcgtctccta gaaggaaact atcctgatac agatcgcttg attccaacag actttaacac
      721 tactattact tttaatgtgg taaacttacg ccagtcaatg gagcgtgccc gtcttttatc
      781 aagtgcgact caaaatggta ctgtgaaact tgaaattaag gatggggttg ttagcgccca
      841 tgttcactct ccagaagttg gtaaagtaaa cgaagaaatc gatactgatc aggttactgg
      901 tgaagatttg accattagtt tcaacccaac ttacttgatt gattctctta aagctttaaa
      961 tagcgaaaag gtgaccatta gctttatctc agctgttcgt ccatttactc ttgtgccagc
     1021 agatactgac gaagacttca tgcagctcat tacaccagtt cgtacaaatt aagtgaaaga
     1081 ggttgagcct ggctcgcctc ttttatgata taatcgaaaa agaaaaggag agtagtatgt
     1141 atcaagttgg aaattttgtt gagatgaaaa aatcacacgc ttgtacaatc aagtcgactg
     1201 gtaaaaaggc taatcgttgg gaaattacac gtgtaggagc agatatcaaa ataaaatgca
     1261 gtaattgtga gcatgttgtc atgatggggc gatatgattt tgagcgaaaa atgaataaaa
     1321 ttattgactg agaaccctta gttagagggt tagcacttta tccctttttg tgttataata
     1381 ttagggattg aaatgaaaac ggagaatgag aaatatggct ttgacagcag gtatcgttgg
     1441 tttgccaaac gttggtaaat caacactatt taatgcaatt acaaaagcag gagcagaggc
     1501 agcaaactac ccatttgcga ctattgatcc aaatgttgga atggtggaag ttccagatga
     1561 acgcctacaa aaactaactg aaatgataac tcctaaaaag acagttccca caacatttga
     1621 atttacggat attgcaggga ttgtaaaagg agcttcaaaa ggagaagggc tagggaataa
     1681 attcttggcc aatattcgtg aagtagatgc gattgttcac gtagttcgtg cttttgatga
     1741 tgaaaatgtg atgcgcgagc aaggacgtga agacgccttt gtagatccac ttgcagatat
     1801 tgatacaatt aatctggaat taattcttgc tgacttagaa tcagtgaaca aacgatatgc
     1861 gcgtgtagaa aagatggcac gtacgcaaaa agataaagaa tcagtagcag aattcaatgt
     1921 tcttcaaaag attaaaccag tcctagaaga cgggaaatca gctcgtacca ttgaatttac
     1981 agatgaggaa caaaaggttg tcaaaggtct tttccttttg acgactaaac cagttcttta
     2041 tgtagctaat gtggacgagg atgtggtttc agaacctgac tctatcgact atgtcaaaca
     2101 aattcgtgaa tttgcagcga cagaaaatgc tgaagtagtc gttatttctg cgcgtgctga
     2161 ggaagaaatt tctgaattgg atgatgaaga taaaaaagag tttcttgaag caattggttt
     2221 gacagaatca ggtgtagata agttgacgcg tgcagcttac cacttgcttg gattgggaac
     2281 ttacttcaca gctggtgaaa aagaagttcg cgcttggact ttcaaacgtg gtatgaaggc
     2341 tcctcaagca gctggtatta tccactcaga ctttgaaaaa ggctttattc gtgcagtaac
     2401 catgtcatat gaagatctag tgaaatacgg atctgaaaag gccgtaaaag aagctggacg
     2461 cttgcgtgaa gaaggaaaag aatatatcgt tcaagatggc gatatcatgg aattccgctt
     2521 taatgtctaa aaattaataa atggtgtcaa ttaggttgga aaaaaattcc aacccttttg
     2581 gcttttgaaa ggaaaaataa atgaccaaat tacttgtagg cttgggaaat ccaggggata
     2641 aatattttga aacaaaacac aatgttggtt ttatgttgat tgatcaacta gcgaagaaac
     2701 agaatgtcac ttttacacac gataagatat ttcaagctga cctagcatcc tttttcctaa
     2761 atggagaaaa aatttatctg gttaaaccaa cgacctttat gaatgaaagt ggaaaagcag
     2821 ttcatgcttt attaacttac tatggtttgg atattgacga tttacttatc atttacgatg
     2881 atcttgacat ggaagttggg aaaattcgtt taagagcaaa aggctcagca ggtggtcata
     2941 atggtatcaa gtctattatt caacatatag gaactcaggt ctttaaccgt gttaagattg
     3001 gaattggaag acctaaaaat ggtatgtcag ttgttcatca tgttttgagt aagtttgaca
     3061 gggatgatta tatcggtatt ttacagtctg ttgacaaagt tgacgattct gtaaaatact
     3121 atttacaaga gaaaaatttt gagaaaacaa tgcagaggta taacggataa atggtgacct
     3181 tattagattt attctcagaa aatgatcaga ttaaaaaatg gcatcaaaat ttaacagata
     3241 agaaaagaca actaatactt ggtttatcaa catctactaa ggctcttgca attgcaagca
     3301 gtttagaaaa agaagatagg attgtgttat tgacgtcaac ttatggagaa gcagaaggac
     3361 ttgttagtga tcttatttct atcttgggtg aggaactcgt ctatccattt ttggtagatg
     3421 atgctcctat ggtggagttt ttgatgtctt cacaggaaaa aattatttca cgggttgaag
     3481 ccttgcgttt tttgactgat tcatctaaga aagggatttt agtttgtaat atcgcagcaa
     3541 gtcgattgat tttaccgtct cccaatgcat tcaaagatag tattgtaaaa atctcagttg
     3601 gtgaagaata tgatcaacac gcgtttatcc atcagttaaa ggaaaatggc tatcgaaaag
     3661 ttactcaagt acaaactcag ggcgaattta gtcttcgagg agatatttta gatatttttg
     3721 aaatatccca gttagaacct tgtcgaattg agttttttgg tgatgaaatt gatggtatca
     3781 ggtcatttga agtagaaaca caattatcga aagaaaataa gacagaactc actatctttc
     3841 cagctagtga tatgcttttg agagaaaagg attatcaacg aggacagtca gctttagaaa
     3901 aacaaatttc aaaaacttta tcacctattt tgaaatcata cctagaagaa attctttcaa
     3961 gttttcacca aaaacaaagt catgcagact ctcggaagtt tttatctttg tgctatgata
     4021 agacatggac tgtctttgat tatattgaaa aagatactcc aatattcttt gatgattatc
     4081 aaaaattgat gaatcagtat gaagtctttg aaagagactt agcgcagtac tttacagaag
     4141 aattacagaa tagtaaagca ttttctgata tgcagtattt ttctgatatt gaacaaatct
     4201 ataaaaaaca aagtccagtg acctttttct ctaatcttca aaagggttta ggaaatctca
     4261 aatttgacaa aatttatcaa ttcaatcaat atcctatgca ggaatttttc aatcagtttt
     4321 cttttctaaa agaagaaatt gaacgatata aaaaaatgga ttacaccatt attctgcagt
     4381 ctagcaattc aatgggaagt aaaacattgg aggatatgtt agaggaatat cagattaaat
     4441 tggattctag agataagaca agtatctgta aagaatctgt aaacttaata gagggtaatc
     4501 tcagacatgg ttttcatttt gtagatgaaa agattttatt gataactgaa catgagattt
     4561 ttcaaaagaa attaaagcgt cgttttcgaa gacaacatgt ttcaaatgca gagagattaa
     4621 aagattacaa tgaacttgaa aaaggggact atgttgtcca tcatatccat gggattggtc
     4681 aatatctagg aattgaaacc attgaaatca agggaattca tcgcgattat gtcagtgtcc
     4741 aataccaaaa tggtgatcaa atttctatcc ccgtggaaca gattcatcta ctgtccaaat
     4801 atatttcaag tgatggtaaa gctccaaaac tcaataaatt aaatgacggt cattttaaaa
     4861 aggccaagca aaaggttaag aaccaggtag aggatatagc tgatgattta atcaaactct
     4921 actctgaacg tagtcagttg aagggttttg ctttctcagc tgatgatgat gatcaagatg
     4981 cctttgatga tgctttccct tatgttgaaa cggatgatca acttcgtagt attgaggaaa
     5041 tcaagaggga tatgcaggct tctcagccaa tggatcgact tttagttggg gatgttggtt
     5101 ttggaaagac tgaagttgct atgcgtgcag cctttaaagc agtcaatgat cacaaacagg
     5161 ttgtcattct agttccgacg acggttttag cgcaacagca ctatacgaat tttaaggaac
     5221 gattccaaaa ttttgcagtt aatgttgatg tgttgagtcg ctttagaagt aaaaaagagc
     5281 agactgcaac acttgaaaaa ttgaaaaacg gtcaagtcga tattttgatt ggaacacatc
     5341 gtgttttgtc aaaagatgtt gtgtttgctg atttgggctt gatgattatt gatgaggaac
     5401 agcgatttgg tgtcaagcat aaggaaactt tgaaagaact gaagaaacaa gtggatgtcc
     5461 taaccttgac cgctacgcca atccctcgta ccctccatat gtctatgctg ggaatcagag
     5521 atttgtctgt tattgaaact ccgccgacta atcgctatcc tgttcagacc tatgttttgg
     5581 aaaagaatga tagtgtcatt cgtgatgctg tcttgcgtga aatggagcgt ggaggtcaag
     5641 tttactatct ttacaacaaa gttgacacaa ttgttcagaa ggtttcagaa ttacaggagt
     5701 tgattccgga ggcttcgatt ggatatgttc atggtcgaat gagtgaagtc cagttggaaa
     5761 atactctatt agactttatt gagggacaat acgatatctt ggtgacgact actattattg
     5821 agacaggggt ggacattcca aatgctaata ctttatttat tgaaaatgcg gaccatatgg
     5881 gcttgtcaac cttatatcag ttaagaggaa gagtcggtcg tagtaatcgt attgcttatg
     5941 cttatctcat gtatcgtcca gaaaaatcaa tcagtgaagt ctctgaaaag agattagaag
     6001 cgattaaagg atttacagaa ttgggctctg gctttaagat tgcaatgcga gatctttcga
     6061 ttcgtggagc aggaaatctt ttaggaaaat cccagtctgg tttcattgat tctgttggtt
     6121 ttgaattgta ttcgcagtta ttagaggaag ctattgctaa acgaaacggt aatgctaacg
     6181 ctaacacaag aaccaaaggg aatgctgagt tgattttgca aattgatgcc tatcttcctg
     6241 atacttatat ttctgatcaa cgacataaga ttgaaattta caagaaaatt cgtcaaattg
     6301 acaaccgtgt caattatgaa gagttacaag aggagttgat agaccgtttt ggagaatacc
     6361 cagatgtagt agcctatctt ttagagattg gtttggttaa atcatacttg gacaaggtct
     6421 ttgttcaacg tgtggaaaga aaagataata aaattacaat tcaatttgaa aaagtcactc
     6481 aacgactgtt tttagctcaa gattatttta aagctttatc cgtaacgaac ttaaaagcag
     6541 gcatcgctga gaataaggga ttaatggagc ttgtatttga tgtccaaaat aagaaagatt
     6601 atgaaatttt agaaggtttg ctgatttttg gagaaagttt attagagata aaagagtcta
     6661 aggaagaaaa ttccatttga tatttttctt ctataaaata gataaaaatg gtacaataat
     6721 aaattgaggt aataaggatg agattagata aatatttaaa agtatcgcga attatcaagc
     6781 gtcgtacagt cgcaaaggaa gtagcagata aaggtagaat caaggttaat ggaatcttgg
     6841 ccaaaagttc aacggacttg aaagttaatg accaagttga aattcgcttt ggcaataagt
     6901 tgctgcttgt aaaagtacta gagatgaaag atagtacaaa aaaagaagat gcagcaggaa
     6961 tgtatgaaat tatcagtgaa acacgggtag aagaaaatgt ctaaaaatat tgtacaattg
     7021 aataattctt ttattcaaaa tgaataccaa cgtcgtcgct acctgatgaa agaacgacaa
     7081 aaacggaatc gttttatggg aggggtattg attttgatta tgctattatt tatcttgcca
     7141 acttttaatt tagcgcagag ttatcagcaa ttactccaaa gacgtcagca attagcagac
     7201 ttgcaaactc agtatcaaac tttgagtgat gaaaaggata aggagacagc atttgctacc
     7261 aagttgaaag atgaagatta tgctgctaaa tatacacgag cgaagtacta ttattctaag
     7321 tcgagggaaa aagtttatac gattcctgac ttgcttcaaa ggtgataaaa tggaaaattt
     7381 attagacgta atagagcaat ttttgagttt gtcagatgaa aagctggaag aattggctga
     7441 taaaaatcaa ttattgcgtt tacaagaaga aaaggaaagg aagaatgcgt aaattcttaa
     7501 ttattttgtt gctaccaagt tttttgacca tttcaaaagt cgttagcaca gaaaaagaag
     7561 tcgtctatac ttcgaaagaa atttattacc ttttacaatc tgactttggt atttatttta
     7621 gagaaaaatt aagttctccc atggtttatg gagaggttcc tgtttatgcg aatgaagatt
     7681 tagtagtgga atctgggaaa ttgactccca aaacaagttt tcaaataacc gagtggcgct
     7741 taaataaaca aggaattcca gtatttaagc tatcaaatca tcaatttata gctgcggaca
     7801 aacgattttt atatgatcaa tcagaggtaa ctccaacaat aaaaaaagta tggttagaat
     7861 ctgactttaa actgtacaat agtccttatg atttaaaaga agtgaaatca tccttatcag
     7921 cttattcgca agtatcaatc gacaagacca tgtttgtaga aggaagagaa tttctacata
     7981 ttgatcaggc tggatgggta gctaaagaat caacttctga agaagataat cggatgagta
     8041 aagttcaaga aatgttatct gaaaaatatc agaaagattc tttctctatt tatgttaagc
     8101 aactgactac tggaaaagaa gctggtatca atcaagatga aaagatgtat gcagccagcg
     8161 ttttgaaact ctcttatctc tattatacgc aagaaaaaat aaatgagggt ctttatcagt
     8221 tagatacgac tgtaaaatac gtatctgcag tcaatgattt tccaggttct tataaaccag
     8281 agggaagtgg tagtcttcct aaaaaagaag ataataaaga atattcttta aaggatttaa
     8341 ttacgaaagt atcaaaagaa tctgataatg tagctcataa tctattggga tattacattt
     8401 caaaccaatc tgatgccaca ttcaaatcca agatgtctgc cattatggga gatgattggg
     8461 atccaaaaga aaaattgatt tcttctaaga tggccgggaa gtttatggaa gctatttata
     8521 atcaaaatgg atttgtgcta gagtctttga ctaaaacaga ttttgatagt cagcgaattg
     8581 ccaaaggtgt ttctgttaaa gtagctcata aaattggaga tgcggatgaa tttaagcatg
     8641 atacgggtgt tgtctatgca gattctccat ttattctttc tattttcact aagaattctg
     8701 attatgatac gatttctaag atagccaagg atgtttatga ggttctaaaa tgagggaacc
     8761 agatttttta aatcattttc tcaagaaggg atatttcaaa aagcatgcta aggcggttct
     8821 agctctttct ggtggattag attccatgtt tctatttaag gtattgtcta cttatcaaaa
     8881 agagttagag attgaattga ttctagctca tgtgaatcat aagcagagaa ttgaatcaga
     8941 ttgggaagaa aaggaattaa ggaagttggc tgctgaagca gagcttccta tttatatcag
     9001 caatttttca ggagaatttt cagaagcgcg tgcacgaaat tttcgttatg atttttttca
     9061 agaggtcatg aaaaagacag gtgcgacagc tttagtcact gcccaccatg ctgatgatca
     9121 ggtggaaacg attttgatgc gcttgattcg aggaactcgc ttgcgctatc tatcaggaat
     9181 taaggagaag caagtagtcg gagagataga aatcattcgt cccttcttgc attttcagaa
     9241 aaaagacttt ccatcaattt ttcactttga agatacatca aatcaggaga atcattattt
     9301 tcgaaatcgt attcgaaatt cttacttacc agaattggaa aaagaaaatc ctcgatttag
     9361 ggatgcaatc ttaggcattg gcaatgaaat tttagattat gatttggcaa tagctgaatt
     9421 atctaacaat attaatgtgg aagatttaca gcagttattt tcttactctg agtctacaca
     9481 aagagtttta cttcaaactt atctgaatcg ttttccagat ttgaatctta caaaagctca
     9541 gtttgctgaa gttcagcaga ttttaaaatc taaaagccag tatcgtcatc cgattaaaaa
     9601 tggctatgaa ttgataaaag agtaccaaca gtttcagatt tgtaaaatca gtccgcaggc
     9661 tgatgaaaag gaagatgaac ttgtgttaca ctatcaaaat caggtagctt atcaaggata
     9721 tttattttct tttggacttc cattagaagg tgaattaatt caacaaatac ctgtttcacg
     9781 tgaaacatcc atacacattc gtcatcgaaa aacaggagat gttttgatta aaaatgggca
     9841 tagaaaaaaa ctcagacgtt tatttattga tttgaaaatc cctatggaaa agagaaactc
     9901 tgctcttatt attgagcaat ttggtgaaat tgtctcaatt ttgggaattg cgaccaataa
     9961 tttgagtaaa aaaacgaaaa atgatataat gaacactgta ctttatatag aaaaaataga
    10021 taggtaaaaa atgttagaaa acgatattaa aaaagtcctc gtttcacacg atgaaattac
    10081 agaagcagct aaaaaactag gtgctcaatt aactaaagac tatgcaggaa aaaatccaat
    10141 cttagttggg attttaaaag gatctattcc ttttatggct gaattggtca aacatattga
    10201 tacacatatt gaaatggact tcatgatggt ttctagctac catggtggaa cagcaagtag
    10261 tggtgttatc aatattaaac aagatgtgac tcaagatatc aaaggaagac atgttctatt
    10321 tgtagaagat atcattgata caggtcaaac tttgaagaat ttgcgagata tgtttaaaga
    10381 aagagaagca gcttctgtta aaattgcaac cttgttggat aaaccagaag gacgtgttgt
    10441 agaaattgag gcagactata cctgctttac tatcccaaat gagtttgtag taggttatgg
    10501 tttagactac aaagaaaatt atcgtaatct tccttatatt ggagtattga aagaggaagt
    10561 gtattcaaat tagaaagaat aatctttaat gaaaaaacaa aataatggtt taattaaaaa
    10621 tccttttcta tggttattat ttatcttttt ccttgtgaca ggattccagt atttctattc
    10681 tgggaataac tcaggaggaa gtcagcaaat caactatact gagttggtac aagaaattac
    10741 cgatggtaat gtaaaagaat taacttacca accaaatggt agtgttatcg aagtttctgg
    10801 tgtctataaa aatcctaaaa caagtaaaga aggaacaggt attcagtttt tcacgccatc
    10861 tgttactaag gtagagaaat ttaccagcac tattcttcct gcagatacta ccgtatcaga
    10921 attgcaaaaa cttgctactg accataaagc agaagtaact gttaagcatg aaagttcaag
    10981 tggtatatgg attaatctac tcgtatccat tgtgccattt ggaattctat tcttcttcct
    11041 attctctatg atgggaaata tgggaggagg caatggccgt aatccaatga gttttggacg
    11101 tagtaaggct aaagcagcaa ataaagaaga tattaaagta agattttcag atgttgctgg
    11161 agctgaggaa gaaaaacaag aactagttga agttgttgag ttcttaaaag atccaaaacg
    11221 attcacaaaa cttggagccc gtattccagc aggtgttctt ttggagggac ctccggggac
    11281 aggtaagact ttgcttgcta aggcagtcgc tggagaagca ggtgttccat tctttagtat
    11341 ctcaggttct gactttgtag aaatgtttgt cggagttgga gctagtcgtg ttcgctctct
    11401 ttttgaggat gccaaaaaag cagcaccagc tatcatcttt atcgatgaaa ttgatgctgt
    11461 tggacgtcaa cgtggagttg gtctcggcgg aggtaatgac gaacgtgaac aaaccttgaa
    11521 ccaacttttg attgagatgg atggttttga gggaaatgaa gggattatcg tcatcgctgc
    11581 gacaaaccgt tcagatgtac ttgatcctgc ccttttgcgt ccaggacgtt ttgatagaaa
    11641 agtattggtt ggccgtcctg atgttaaagg tcgtgaagca atcttgaaag ttcacgctaa
    11701 gaacaagcct ttagcagaag atgttgattt gaaattagtg gctcaacaaa ctccaggctt
    11761 tgttggtgct gatttagaga atgtcttgaa tgaagcagct ttagttgctg ctcgtcgcaa
    11821 taaatcgata attgatgctt cagatattga tgaagcagaa gatagagtta ttgctggacc
    11881 ttctaagaaa gataagacag tttcacaaaa agaacgagaa ttggttgctt accatgaggc
    11941 aggacatacc attgttggtc tagtcttgtc gaatgctcgc gttgtccata aggttacaat
    12001 tgtaccacgc ggccgtgcag gcggatacat gattgcactt cctaaagagg atcaaatgct
    12061 tctatctaaa gaagatatga aagagcaatt ggctggctta atgggtggac gtgtagctga
    12121 agaaattatc tttaatgtcc aaactacagg agcttcaaac gactttgaac aagcgacaca
    12181 aatggcacgt gcaatggtta cagagtacgg tatgagtgaa aaacttggcc cagtacaata
    12241 tgaaggaaac catgctatgt ttggtgcaca gaatcctcaa aaatcaattt cagaacaaac
    12301 agcttatgaa attgatgaag aggttcgttc attattaaat gaggcacgaa ataaagctgc
    12361 tgaaattatt cagtcaaatc gtgaaactca caagttaatt gcagaagcat tattgaaata
    12421 cgaaacattg gatagtacac aaattaaagc tctttacgaa acaggaaaga tgcctgaagc
    12481 agtagaagag gaatctcatg cactatccta tgatgaagta aagtcaaaaa tgaatgacga
    12541 aaaataaccc tgagagaggc tggagcctct cttttttgtg cagtttagga gctaaaggga
    12601 acagaatgga gaaaatggaa caaatgtgtt ttctaatctg ttagactgta tctagaaagg
    12661 ggaaaattat gattaaagaa ttgtatgaag aagtccaagg gactgtgtat aagtgtagaa
    12721 atgaatatta ccttcattta tgggaattat cggattggga ccaagaaggc atgctctgct
    12781 tacatgaatt gattagtaga gaagaaggac tggtagacga tattccacgt ttaaggaaat
    12841 atttcaaaac caagtttcga aatcgaattt tagactatat ccgtaagcag gaaagtcaga
    12901 agcgtaaata cgataaagaa ccctatgaag aagtgggtga gctcagtcat cgtataagtg
    12961 agggggggct ctggctagat gattattatc tctttcatga aacactaaga gattatagaa
    13021 acaaacaaag taaagagaaa caagaagaac tagaacgtgt cttaagcaat gaacgatttc
    13081 gagggcgtca aagagtatta agagacttac gcattgtgtt taaggagttt actatccgta
    13141 cccactagga agt
//
LOCUS       DAVLUM010000055        13151 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLUM010000055 DAVLUM010000000
VERSION     DAVLUM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.055"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            223..570
                     /locus_tag="VYN42_001538"
     CDS             223..570
                     /locus_tag="VYN42_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1462590.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(849..1685)
                     /locus_tag="VYN42_001539"
     CDS             complement(849..1685)
                     /locus_tag="VYN42_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1462591.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(1698..2327)
                     /locus_tag="VYN42_001540"
     CDS             complement(1698..2327)
                     /locus_tag="VYN42_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1462592.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(2337..2978)
                     /locus_tag="VYN42_001541"
     CDS             complement(2337..2978)
                     /locus_tag="VYN42_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1462593.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(3124..4353)
                     /locus_tag="VYN42_001542"
     CDS             complement(3124..4353)
                     /locus_tag="VYN42_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1462594.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(4343..5509)
                     /locus_tag="VYN42_001543"
     CDS             complement(4343..5509)
                     /locus_tag="VYN42_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1462595.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            5653..6666
                     /locus_tag="VYN42_001544"
     CDS             5653..6666
                     /locus_tag="VYN42_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1462596.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQLISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(6711..7130)
                     /locus_tag="VYN42_001545"
     CDS             complement(6711..7130)
                     /locus_tag="VYN42_001545"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1462597.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(7141..8547)
                     /gene="atpD"
                     /locus_tag="VYN42_001546"
     CDS             complement(7141..8547)
                     /gene="atpD"
                     /locus_tag="VYN42_001546"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1462598.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(8633..9511)
                     /locus_tag="VYN42_001547"
     CDS             complement(8633..9511)
                     /locus_tag="VYN42_001547"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1462599.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(9527..11032)
                     /locus_tag="VYN42_001548"
     CDS             complement(9527..11032)
                     /locus_tag="VYN42_001548"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1462600.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(11047..11583)
                     /locus_tag="VYN42_001549"
     CDS             complement(11047..11583)
                     /locus_tag="VYN42_001549"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1462601.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(11583..12077)
                     /gene="atpF"
                     /locus_tag="VYN42_001550"
     CDS             complement(11583..12077)
                     /gene="atpF"
                     /locus_tag="VYN42_001550"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1462602.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(12091..12807)
                     /gene="atpB"
                     /locus_tag="VYN42_001551"
     CDS             complement(12091..12807)
                     /gene="atpB"
                     /locus_tag="VYN42_001551"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1462603.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12842..13042)
                     /locus_tag="VYN42_001552"
     CDS             complement(12842..13042)
                     /locus_tag="VYN42_001552"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1462604.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         4054 a         2914 c         2330 g         3853 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 aataaaatag gctccataat atctataggg gatttaccca ctacaaatat tatagagcct
      121 aaaagatgag accaaccaac ctcatctttt ttcgtatcaa atctaagcaa ttttagaaac
      181 tttatggcat actagactta tcaatgaaag cgaggtaatc tcatggaaca atttttagat
      241 aacatcaaag accttgaagt cactacagtt gtgcgtgcgc aagaagctct tgataaaaaa
      301 gaaactgcaa ccttctttat cggtcgcaaa acttgccctt actgccgtaa atttgcaggt
      361 acattgtcag gtgtcgtagc tgaaaccaaa gctcacattt acttcatcaa tagtgaagaa
      421 ccaagccaac tcaatgattt gcaagcattc cgctcacgct atggaatccc aactgtacca
      481 ggttttattc atattacaga tggacaaatc aacgtccgtt gcgactcttc aatgtcagca
      541 caagaaatca aagatttcgc aggattgtaa aaaatcagct aacaagtctt aaaatcacaa
      601 aaacgcataa tgtaaggtgc aaaaaccttg atattatgcg ttttattgtt cctaaaacag
      661 ttacatcagc atttcattac agaacatttt aattttggaa gtcaaatcaa tttttaacaa
      721 tattttagaa atcacagtgg gctattccat attcaattat ccagattcaa tcgctattat
      781 cgttttccta gattacaaaa aaaactacgt tttgctaatc aaaacgtagt ctcagccact
      841 attttatctt actgtccttc ttttacttct ttggttgcta catcttctcc aaaccatttt
      901 tggctgattt cttggaactt gccgtccttg taaagactag aaaaagcttc atttatcttc
      961 ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa aagcttctgt ttctagtcca
     1021 actgtaaaga cattataatc gtttaaaaca ccttctgctt ctaaataata gtttgcatag
     1081 acacggtcaa tcaatagacc atcaattcga tcgtttttca aatcaatcaa ggcttcatta
     1141 aaggtttggt attgattcgc ttccttatta gcgacaatat tcttcaaaag ttctggattt
     1201 gcttcaaagt ccgcataacc agatgaacca gcttgagctc ctaatgtctt tccagtcata
     1261 tcctttgcag tcgtgatacc agatgatttc ttcgtaacca atacctgctc attcttcata
     1321 tatgagttac tgaaagccac cttttcacgg cgttcgtctg tagcggaata gccattccaa
     1381 atcagatcaa tcgttccttt tgtcaattca gcttctttca aatcccaatc aatcggttgc
     1441 caatttaccg tgattccgta tttttcaaaa acagctgtag ctaaatcaat atcaaatcct
     1501 gcataagaac catctttctg agcaaatccc attggaacaa aagtactatc aaatccaata
     1561 gtaatagact tgttagactg gtactttgac caattatctc cactagtttc gctagaattt
     1621 ttcccacaag ctactaagaa caaagcagtc atcagactga ctaatacaag catccatttt
     1681 ttcatccatt tttcctccta tttaggttct actttcaata atacatctgc gatattttca
     1741 gcaaactgca aatcatgggt aaccacaatc tgggtcatcc caagttccct attttgcaag
     1801 attagcttct ccacttccaa acgtaattct ggatccaggg cagaagttgg ttcatcgtag
     1861 ccaatgattt ctgggtcaat catcatagca cgcgccaaag ccactcgctg cttttgccca
     1921 ccagatagtg agaaaggata ggcctctgcg tgtcctccta gtcctaactg ttccaagagt
     1981 ccactcgcct tcttctcagc ctcttcctgc ttcattccca tggtcttcac aggcgataaa
     2041 gtcaaatttt ccagaactga tagatgagga aatagttgaa aatcttggaa gacaaatccc
     2101 agtaggttgc gcttctgcaa ttcatccagc tctaaaggtt gtccattata aaagatttgc
     2161 cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa gagttgtctt acctccacca
     2221 gaaggtccaa cgatagccag gatttgcttt tcaggaatac ttagactgaa attagacagg
     2281 atttgtttgt ctccaaagac tttattgata tttcgtaatt ctaacatggc agcctcctat
     2341 ctataataac tatacttctt ctcaactttt ttggaaataa ttgtcacaat cccaatcaaa
     2401 atcaaataaa tggctcctgc caagaacata ggaactagac tagcatcgcg gttagcagct
     2461 gttcgactag ccaagataag gtctgaaatt ccgagagcat agaccaaaga agtatccttg
     2521 accaaactca taacttcatt aaagacacta ggaagaacaa tcttggtcac ttggggcaag
     2581 ataatatagc gcactctgtc aaaagggcta aactttaaga ccttggcagc ctcatactgt
     2641 cctcttggaa tagtgtcaat tcccccacgg aaaatttctg caaagtaagc tgcatagttg
     2701 agaacaaagg caataatagc tgcaggaagg cggtctaaac gaatcccaat acttgggagc
     2761 acataataga taaaaatcag ttgcaagagt aagggggttc ctcgcataac ccagatgtaa
     2821 atgttaatca gataatggag gggcttccaa tggacttgca aggcaaaggc aatcaaaacg
     2881 cccaagggaa tcgaaaatag caagaccagt gcaaagacct gtacagtcgt gctcgcacca
     2941 ttcagtaaac tcggtaatat ctcaaataaa taagacatac tgcacctcct aaaagtaatt
     3001 gttcctatta tagcatgaat aaacaagatt accaagtatt tttgtaaaaa gattctacca
     3061 tatacaaata aaaaccgtag ctatcaaaag agataaacta cagttctata tgtttaaaca
     3121 ttcttacaat ctctcaaaca gttcttgcat ttgcacatca tctggaacca gttttaagta
     3181 agtgtgagca tggacttttg cttcttcaaa atgtcccaat tcacgcaaga gatagatata
     3241 gtgttccaga aattctggat tgtccttcaa atctcctgtc aactcttgat aatgctcata
     3301 agcagtatcc aaatcgtcca tttcttgata agaacgagca atcatccact tggtcaaaag
     3361 attttctggc tcctcactct gcaagtctag aatatcctca taacgctcct gctccagata
     3421 aatagtggct aaacgaagca agatttcttc tgtatcctca gcgtcttctt ttgcagtaag
     3481 gagataattt tctgcaccac tagcatcatg caattcataa gaaaattgtg aagcagctag
     3541 caagaggcga gtttcaaagg gatttttctc taatccttgc ttagcgatac gcagggcttc
     3601 ttgaacttga tgttccttat gtaaagcctg actgtaccca tactcatagc cttcaaagtc
     3661 aggagaaatg gtatcaagct gcttaaagta gagggtggct ttttgatatt cttcttgatc
     3721 aaaataaaga ctggccaact caaaagctgt taagtcatcg tattctaact ccagggcttt
     3781 ttctaaaaac tcagtagccg tttcaaattt ccctaactga gcataggcaa agccaattcg
     3841 ttgataggtg gaaatgcccg tttgctcata aatcgagcga ttatctaact gggcataggc
     3901 ttgaatagcc gcttggtaat tttccaactc actatccaac tctgccaaac ccaatatcaa
     3961 gagagaatcc tctgagtagg tcaaggcctc caataatttc tcacgtgcca catctgtcaa
     4021 accttccagc tggtaaaggt ctgccttcaa aaccaaagac gagacatacc agtcactgtc
     4081 agcttggatt tcctcaagat aggtaaaggc ttcttctatt tgaccatcct cgctagcaat
     4141 tgcagctaga ttaagatgaa cctctggaaa atcctctaca attttcaggt aaatttcctt
     4201 ggcctgagga tagaaaccaa tcccttcaag ataagttgcc aactcataca gaagattact
     4261 tgaatcattt tctaaagctt tggcgaaata atgctcagcc ttagttaaat cttgctcctc
     4321 caaagcctgt aacatctgtt gactattgtt cactcttgac ttcctcaccc tctaattcat
     4381 atagaccact gactacctta taccattcga aaatggctga aatgacaacc ttagcagagg
     4441 cataaaccgg aataccaagt aaaactcccc agataccaaa catagatcct gaagttaaca
     4501 aaacaaagag aacattaata ggatggatgt ttaattgact tcccaaaatc aatggagaga
     4561 caaaacggcc ttcaatagtt tgttctacga taaagacaat cactactttc aaaagcatga
     4621 ctggaccagc aatcaaaccc aatactagag caggaagcat ggctagaaag ctaccaagat
     4681 aagggaccag atttaaaata ccagcagtaa cccccagcgt aaccgcatag cgtagaccaa
     4741 taatcttgaa gaagatgata aacattactg ctacaataat agccactgtc acttgccctc
     4801 gaacatagtt ggacaactgt tgattcacat ctgataaaac ttgtccaaca ggttccttca
     4861 attttcttgg aatgaattgg gtcaaatagt tacgcaagcc tttcccatca cgcaagagat
     4921 aaaagagcat gaaaggaacg ataatcaagg caacaatcac ttgagaagcc ccgctaataa
     4981 aggcactcac ccagttgact gcctgagatg aaaccttact tgccaaaact gtagcctggc
     5041 tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa atcatctggc aggtgctggg
     5101 ctaccaatcc attaacaatc ctatctatat cttctaagta aacaggaacg tttcttgcaa
     5161 aggtcaaaac ctgacgttgc agatttggaa tggcgactgc caagccccaa atgataaaga
     5221 gagcgatgat aacaaagaca atagtgatag ctataacacg attaacctta tgcttctcca
     5281 tccaatcaac aataggattc aacaaataat ataacaaacc agacaaaatg actggcaaca
     5341 tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa actaatctta cttaaaataa
     5401 aaagattcag tcccaataat aaggttacta aaaataccgt aattgccttg ttatctaaaa
     5461 accacttgaa aaaccaagat aggctaaaat gtttctcttt ttgctccata aatacttcct
     5521 ttctattgtt ctctcattat accatttttg aaacaaaata actctttttt aaagtgctta
     5581 catctaattg gatgtcttta atttgcttat ttttgtgata taatagtctt atctttacac
     5641 agaggtatag taatgaaaga aactgtttat tttggaactt atacacgtcg tacttctcaa
     5701 gggatttaca aggcagactt tgatacagaa actggtcagc tttcaaatct agaacttttt
     5761 gcagctgagc caagtccaac ctaccttgcc tttgaccagc accaacattt atacactgtt
     5821 ggtagccaag acgataaggg gggaattgca gcctatcaaa ctgacgggac tgtgttaaat
     5881 catgttgttg aagaaggagc tccccactgt tatgttgctg tcgatgaaaa gcgtgatttg
     5941 gtttacgcag ccaactatca caagggacaa gtccttgttt ataaacgcca ggaagatggt
     6001 agtcttctac ttagtgatat ggatcaacac agtggccaag gtccacatga aaatcaagct
     6061 tccccccatg ttcactatac agatttaaca cctgaccact atctagtgac ctgcgacttg
     6121 ggaactgacc aagtcatcac ctatgacctc gatcaagaag gaaaattatc taagctctat
     6181 acctatcaca gcaagccagg agcaggctca cgccatatca ttttccataa ccactataaa
     6241 atcgcttatc tcatttgtga actcaatagt actatcgaag ttttaatcta cgatggcgtt
     6301 ggcgaatttg tacgtatgca gcttatttca actttaccag aagcttacga aggctttaat
     6361 ggaaccgctg ctattcatct ctctaaagac ggtaaatacc tctacgcttc taaccgtggc
     6421 catgattcta tcgcagtata taccatcctt gcggacggta gcttagagtt attagaaatc
     6481 gttccaacgc atggtcagac tccacgtgat tttgatttga cccccgacca aaaatttctc
     6541 attgttgtcc atcaagactc tgacaatgca actgtcttta aacgtaattg tgacaatggt
     6601 cgtctagcag aactctccaa cgacttccat gttcccgaag cagtctgcat ccgttttgct
     6661 ccttaaaaca ccataaaaaa tgaacttggt attttcaagt tcattttttc ttatagtcta
     6721 tttccgacat taatacggtt aatagcacgt tgcaaagcaa tcttagcacg acgttcttgg
     6781 tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt ctgcacgaag tttggcacgt
     6841 tctgcacgac tgatatcgat atcacgagca cgttctgcag agtcagcgac gattgtgatc
     6901 atatcattgg caatttcaat aacgccaccg tttactgcaa tccagttcac gtgatcttta
     6961 tcatcgatac gttttacctt tacttcatca actgctaaaa ccgcaatcat attttcatgt
     7021 cgtggcaaga tccccatctc accatccaga gttcgaaccg atacatagct ggcatggtga
     7081 tcatagacga gaccatctgg tgtcacgatc tggacagtta actgagccat agatcacctc
     7141 ttaaaatccc attttttcag cttttgcaat cacatcttcg atagaaccta caccacggaa
     7201 ggcatcttct ggcaagtggt cgtatttacc atcaaggatt tccttaaagc cacgtacagt
     7261 ttcagcaact ggaacataag aacctggctg accagtaaat tgttccgcaa cgttgaagtt
     7321 ttgtgacaag aagaactgga tacgacgggc gcgagcaacc aaggtctttt cttcatcaga
     7381 aagctcatcc ataccaagga tagcaatgat atcttgcaat tcatggtaac gttgaaggac
     7441 acgttttact tcagcagcaa ctgcatagtg ctcttctcca acgatttcag gtgccaaggc
     7501 acgtgagctt gaagcaagtg ggtcaacggc tgggtagata cccaattgta ccaacttacg
     7561 ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt gctggcgctg ggtcagtata
     7621 gtcatccgct ggcacataga tagcctggat agaggttaca gaacccttct tggttgatgt
     7681 gatacgttct tgcaattgac ccatttccgt agcaagtgtt ggttggtaac caacggctga
     7741 tggcatacga cccaaaaggg cagatacttc tgaaccagcc tgagtgaaac ggaagatatt
     7801 atcgataaag agaagcacgt cttggccttc cacatcacgg aagtattcag cgattgtcaa
     7861 accagtaagg gcaacacgca tacgtgctcc tggtggctca ttcatctgac caaagaccat
     7921 ggctgttttc tcgataacgc ctgattcttt catttcccag taaaggtcat tcccctcacg
     7981 agtacgttcc ccaacaccag taaatactga aataccaccg tgctcttggg caatgttgtg
     8041 aatcaattct tggattaaga cggttttacc aactccggca ccaccgaaaa gtccaacttt
     8101 accaccttta aggtaagggg caagaaggtc aataaccttg atccctgttt caaggatttc
     8161 agaagaggta gacaactcat caaaagttgg agctttttta tgaattggct gacgctctgc
     8221 gtcttctgta aaaggagctt ccaaatcaat ggtatctccc aaaacgttga agacacgtcc
     8281 caaagtttct ttacctactg gtacagagat tggacgacct gtgtccaata cttccattcc
     8341 acgagtcaac ccatctgttg attccatggc gatagtacga accataccat ctcctaactc
     8401 caaggctact tcaaggacga tttttgtttt tctttcgtca tttttgtaga cgacaagtgc
     8461 attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa acgtctacaa cgggaccgat
     8521 aacctgagca attttacctg aactcatctc cttctcctat tctatataag atactgtcgg
     8581 ttcctagctc aactaggtcc taagttcatt ttcatacgag ctggactaga gcctattcta
     8641 aggcactagc acctgctacg atttctgtaa tttcttgtgt aatcgccgcc tgtctggcac
     8701 ggttatactg aattgtcaaa tcattgatga ctttcttagc attatctgtc gctgtttgca
     8761 tggctgtcat acccgcagca ttctcagctg tcttggcatc gataatggca ccgtaaatca
     8821 tactttctgc aaactgaggc aacaactgct ccagaatttc ttctcggctg gtttccaatt
     8881 caaaagtcaa gctgtactct tcatccgctt catttggatc caagtcaaca atcggaagca
     8941 tttgttccac acgcatttga ctggttagcg tattgacatg gtggttgtag caaacataaa
     9001 gctcatcaaa gagttcattt tggtacattt caacagtttt tgaaataatc ttacgaactt
     9061 gatcaaagct aggttggtct gccaagccac gtaattcata aagtggttga ataccgcgag
     9121 ccttaaagaa atcagctccc atcccaccga tacagatcat ttcaaaacct ttaccgtctg
     9181 ggtggtattc ttctttcaac tccataacag ctttcaaaat agaggaatta taacctccaa
     9241 ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt cttcacagaa cggctaatca
     9301 acatcggatt agttgaagca ccagctccat taccatgaag gatatctgtc aaaagtttac
     9361 gcactttctg agcgtaaact tggaagttgc gagcagcttc ttcagagcga cctaacttag
     9421 cagccgatac catttgcata gcattagtga tttgactcgt attttttgtt gaggcgattt
     9481 ttgttttaat atcatttaga gacactgcca tctgacacct ctattcttat tggaagctag
     9541 attgattgag aaactctgta atcgcagcat ccaagactgc ttcttctggc aagtcttttg
     9601 tatcacgaat ggtttccaaa atctctggat gttgagcatc aaagaaggca tggaactctt
     9661 cctcgaaacg aacaatatca tctactggaa cagtatccaa gaaaccatgt gtcaaagcat
     9721 aaagaatggt tacttgtttc tcaacaggta atggtttgtg aacaggttgt ttcaagacct
     9781 caacggtacg acgtccacgg ttcaacttag cctgtgttgc tgcgtccaag tcagaaccaa
     9841 acttagtaaa ggcttccaac tcacggtatg aagcaaggtc gatacgaagt gtaccagcaa
     9901 ccttcttcat ggctttgatt tgtgcagaac cacctacacg agatacagat gaacccgcat
     9961 cgatggctgg acgaatacct gcattgaaga ggccatcgcc aaggaagatt tgtccatcag
    10021 tgatagaaat cacgttggtt gcgatatagg ctgagatatc tcctgcttgt gtctcgataa
    10081 atggtagggc tgtaattgat ccaccaccaa gttcatcaga aactttagct gagcgctcaa
    10141 gcaaacggct gtggagatag aaaacatccc ctgggaaggc ttcacgacct ggaggacgac
    10201 gaagcaagag cgatagttca cgataagcta ccgcttgttt tgatagatca tcgtatacaa
    10261 tcaaaacatg cttaccttga tacataaatt cttccgccat agcaacccca gtataaggag
    10321 ctaggaagag caatggagat ggttgtgaag cagaggctgt cacaacgatt gtgtagtcca
    10381 aggcaccgta ctgacgaagt gtttctactt gcgtacgaac tgttgattct ttttgtccaa
    10441 tcgcgacgta gatacagatc atatcttgat ctttttggtt caagattgta tcaatcgcaa
    10501 tggttgtttt ccctgtctga cggtcaccga taatcaactc acgttgacca cgaccaatcg
    10561 gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg ttctgaaaca gacttacgtt
    10621 gcataacacc aggagctggt gcttctactg gacgagtttt atcagtgtgg atttctccaa
    10681 gaccgtcaac tggacgacca agcggatcca caacacgacc aatcagactt tcacctacag
    10741 ggacttccat gattttccct gtacggcgga ttgtatcgcc ttcacggata tctgtaaagt
    10801 cacctaggat gataatacca acgtctgttg actccaagtt ttgagccata ccataagagc
    10861 cgttttcaaa attcaacaac tctccactca tgacattttc aaggccatga gcacgcgcga
    10921 taccgtcccc gatataggtt acaacacctg tttcagtcac atcaaaattg ggtttgaaat
    10981 tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc gttaattgcc aaaagaacac
    11041 cactttctat ttcaaatttt ctttaacaac tttaagttgt tgtttaatac tcacatcaat
    11101 tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga ctttcatcga tttgttcttt
    11161 tacactcctt actttcagag acattttttt ctcaatcaaa gggagcaaac gagtcttctg
    11221 ttcatcagtt agaggatgag cagacgtaat cgtcacttca aatcgatttg tttctttttc
    11281 aagtcggttc aagcaatcta caagcacatc ataaaaaaga tttgctctgt gattgtaggc
    11341 cagaacctgg ataaagtttt gtaataaagg cgacacagaa tcttggaaaa aagcaattgt
    11401 tttttcctta tccgactcgt ctactgccac ttgttttaaa aaagaaggca gacctgtttt
    11461 ttcaacaact tgcttgattt gagtcaagtc tgaaaagata cggtcttctt ctcctttttc
    11521 aagtaccaat tggacaaaag gcatgctgta tttttcaatt acctttactg ttttcttgtc
    11581 cattaagctt ctcctagctg atcgatatac tgatcaatga gtgctttatg ggcatgactg
    11641 tcaaggtttt gtgagatgat tttaccagct aagctgatgg tcaaatctgc gacctcaccc
    11701 ttaacactct gtaaagcttc tactttattt tgagcaattt cttgattggc tttttctttt
    11761 aagtgtcctg cttctagttt agcatctgct aagatattag ccttactttg ctcagctgtt
    11821 tcctttgcat tttcaatgat tgtcttagct tctttacggc taccagccaa ttcatcttcg
    11881 cgtttttgag ccaatacttc tgctttttga cgggcttctt cagctctgtc aatatctgaa
    11941 gcaatttttt cagctctttc ttcgaaaatg cctgtaatat tagaccatgc aaatttttta
    12001 atcaagacta gcaaaagaat aaaagagcca gtgattaaaa caaaattacc aattaattca
    12061 cctactgtta cgtgcatcag ttactccttt ctattcctct tcaatattaa tcttattccc
    12121 taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg atgcaggaaa taaagacaga
    12181 aaatgcagtc caagccaaat tagctccaaa ggctactgga taccaataaa tagcttggtg
    12241 ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca aagatattcc caaaaatccg
    12301 caaagccaaa gataagaagt ttgtaaattc ttccaagata ttcatcggta tgacaaaaac
    12361 aggactcata aaagatttta tacttttttt aaatccacga cgacgaacgc tttctatatg
    12421 tgtcaacaaa atgacaagaa aagataaggt taagtcatac tgtaaattag cggttggcga
    12481 actccaccag ttagtcccat cgatcgtttg aatctttgtc attaagccaa ggttattggc
    12541 aatcaccatg aaaaggaata aacaaaggaa aaagagtgag taatctttca tgtagcgcga
    12601 accaatgtta ggttctgtaa atccaataac aaagtcatag acatactcaa gtacattttg
    12661 ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa taaataaaga caaaaataac
    12721 tcccacaatc aacaaagtca tggctaacat agtcagattg aagataacag gaccaataga
    12781 gatgattgga ttaatacttt cttccatcta aaatcctccc ttttcttctc gttccatgta
    12841 tttatttgat aataaatgag aagacaagag ttacaaagaa agttccttca ataaaggcaa
    12901 cacctaaaaa catcaaacta cgaaactcag aaagcatatc tggttggcgt gctactgatt
    12961 taaacagtcc attcatcaat aaaccttcac cgacagatac gcccatacag gcaatacata
    13021 agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa ataaaattta cttacttagt
    13081 gtagtcctaa aatttaaatt tgtcaacttt taaccgctat tggaagcgtt taataaaaat
    13141 tatttccatt t
//
LOCUS       DAVLUM010000056        12576 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLUM010000056 DAVLUM010000000
VERSION     DAVLUM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.056"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(123..326)
                     /gene="blpN"
                     /locus_tag="VYN42_001553"
     CDS             complement(123..326)
                     /gene="blpN"
                     /locus_tag="VYN42_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV1462605.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(342..596)
                     /gene="blpM"
                     /locus_tag="VYN42_001554"
     CDS             complement(342..596)
                     /gene="blpM"
                     /locus_tag="VYN42_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV1462606.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            878..3031
                     /gene="blpA"
                     /locus_tag="VYN42_001555"
     CDS             878..3031
                     /gene="blpA"
                     /locus_tag="VYN42_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEV1462607.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3042..4403
                     /locus_tag="VYN42_001556"
     CDS             3042..4403
                     /locus_tag="VYN42_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1462608.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4460..4615
                     /gene="blpC"
                     /locus_tag="VYN42_001557"
     CDS             4460..4615
                     /gene="blpC"
                     /locus_tag="VYN42_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1462609.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(4659..5999)
                     /locus_tag="VYN42_001558"
     CDS             complement(4659..5999)
                     /locus_tag="VYN42_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1462610.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6013..6750)
                     /locus_tag="VYN42_001559"
     CDS             complement(6013..6750)
                     /locus_tag="VYN42_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462611.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6755..7093)
                     /locus_tag="VYN42_001560"
     CDS             complement(6755..7093)
                     /locus_tag="VYN42_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462612.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7369..7698
                     /locus_tag="VYN42_001561"
     CDS             7369..7698
                     /locus_tag="VYN42_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1462613.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDLRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7866..8915)
                     /locus_tag="VYN42_001562"
     CDS             complement(7866..8915)
                     /locus_tag="VYN42_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1462614.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(8912..9643)
                     /locus_tag="VYN42_001563"
     CDS             complement(8912..9643)
                     /locus_tag="VYN42_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462615.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVADPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9711..10121
                     /locus_tag="VYN42_001564"
     CDS             9711..10121
                     /locus_tag="VYN42_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1462616.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATNASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10131..10418
                     /locus_tag="VYN42_001565"
     CDS             10131..10418
                     /locus_tag="VYN42_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462617.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10580..10774
                     /locus_tag="VYN42_001566"
     CDS             10580..10774
                     /locus_tag="VYN42_001566"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462618.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSNHTHD
                     KPTLTWFEEIFEEYHSPFHN"
     gene            complement(11108..12244)
                     /gene="dnaJ"
                     /locus_tag="VYN42_001567"
     CDS             complement(11108..12244)
                     /gene="dnaJ"
                     /locus_tag="VYN42_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1462619.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
BASE COUNT         4060 a         2750 c         2197 g         3569 t
ORIGIN      
        1 gatgttaatt caatagtctt ttgtttttta tcagagatac ttatggatag ataaataaga
       61 taggtttgaa aagcgaagag aataataaag aatatagcct tcataaaatt tagctttcat
      121 ttttatgatg tagcggtata ggctaaatat ccacaaacca ctgctcctcc aattcctcct
      181 attgcagcgc cccatggtcc tagaattttc ccatatttca ctccacccgc tgcacaacct
      241 aaagcagcaa ctacagctgc tcctccggaa ttacctccgt aaacctcact cagcattgtt
      301 tcatttatat tacaataagt attcatacaa gtctcctttt gttaaaatcc acccgttgcc
      361 cctgttactc ctgcccaaag agccacacca aatttagctc ctatgtatcc acatgctccc
      421 ataaatggcg ctccaacacc actcgcagca caaatagctg tccctaaccc ccagccacca
      481 aaagcagcac taccaccttc gaaaacatta gtttgccaat tattcttgcc tccttcaata
      541 ctagataaca tagctatatc catttcatga aattgttcca tcatttttgt attcataaca
      601 aatactcctt ttttattttt aatttttgtc ttgttgcaac tttgacaagt ttagtatagc
      661 actatttgtt aaagtttttc atccaaatct tgaattgtca tcgaaacgtc ttaaattagc
      721 ttttttattt aaaactacct ctaaattttt tttaaaagat aatttctaat cactttttta
      781 ccattcagga aatttcaatg actattcaag attttataaa gcacgaaatt gtttttatgt
      841 cataatagag ctatccacta tatgaaagga attgccaatg acttcttata aacgtacatt
      901 tgttcctcaa atagatgcga gagactgcgg tgttgctgcc ttagcctcga ttgctaaatt
      961 ctatggttca gatttttctc tagctcactt gagagaactt gcaaagacca ataaagaagg
     1021 gacgactgct cttggcattg taaaagccgc tgatgaaatg ggctttgaaa caaggcctgt
     1081 tcaagcagat aaaactctct ttgacatgag tgatgtcccc tatccattta tcgttcacgt
     1141 taacaaagaa ggaaaactcc aacattacta tgttgtctat caaacaaaga aagactatct
     1201 gattattggt gatcctgacc cttctgtaaa aatcactaaa atgtcaaaag aacgcttttt
     1261 ctctgaatgg actggagtag ctatttttct agctcccaaa cccagctatc aaccccataa
     1321 agataaaaag aatggtctac taagcttcct tcctctgatt ttcaaacaaa aatctctcat
     1381 tgcttacatt gttctctcaa gcttattggt cactattatc aatatcggtg gttcttatta
     1441 tctccaagga atcttggatg aatacatccc aaatcagatg aaatcaactt taggaatcat
     1501 ctcagttggt ctggttatca cctatatcct ccaacaagtc atgagctttt ccagagatta
     1561 tctcctaacc gttctaagcc agagattaag cattgatgtg attttatcct atattcgcca
     1621 tatttttgaa cttcccatgt ctttctttgc gacacgtcgt acaggagaaa tcatttcacg
     1681 gttcacagat gctaactcta ttatagatgc cttggcttct accattcttt ctctttttct
     1741 ggatgtttct attctgattc ttgtaggggg cgtcttactg gcacaaaacc ctaatctctt
     1801 cctcctttct cttctttcca ttcctatata catgttcatc atcttttctt ttatgaaacc
     1861 tttcgaaaaa atgaaccatg atgtcatgca aagtaattct atggttagct ctgccattat
     1921 cgaagatatc aacgggattg aaactataaa gtcgctcacg agtgaagaaa atcgctatca
     1981 aaatatagac agcgaatttg tagattattt ggaaaaatcc tttaagctca gtaaatattc
     2041 tattttacaa acgagtttaa agcagggaac aaaattagtt ctgaatatcc ttatcctatg
     2101 gtttggcgct caattagtca tgtcgagtaa aatttctatc ggtcagctga ttacctttaa
     2161 cacacttttt tcttacttta caactcctat ggaaaatatt atcaacctcc aaaccaaact
     2221 ccaatctgcg aaggtcgcta ataaccgttt gaacgaagtc tatctagtcg aatctgaatt
     2281 tcaagttcaa gaaaaccctg ttcattcaca ttttttgatg ggcgatattg aatttgatga
     2341 cctttcttat aagtatggtt ttggacgaga taccttaaca gatattaatc tcacgattaa
     2401 acaaggagat aaggttagcc tagttggagt tagtggttct ggtaaaacaa ctttagccaa
     2461 aatgattgtc aatttctttg aaccctacaa agggcatatt tccatcaatt atcaggatat
     2521 taaaaacatt gataaaaaag tcttgcgccg tcatattaat tacctacccc aacaagccta
     2581 tatctttaat ggctctatct tggaaaattt aaccttgggc ggtaatcata tgattagcca
     2641 agaagatatt ctaagagctt gtgaattagc tgaaatccgt caagacattg aaagaatgcc
     2701 tatgggctat caaactcagc tctctgatgg agctggtcta tcaggaggac aaaagcaacg
     2761 aatcgctctc gctcgtgctc ttttaactaa agctcctgtt ttaatactag atgaagctac
     2821 tagcggtctt gatgtcttga ctgagaaaaa ggttatagat aatcttatat ccctaactga
     2881 taaaaccatt ctctttgtag cccatcgtct cagtatagcc gaacgaacta accgtgtcat
     2941 tgttcttgac caggggaaaa tcattgaagt tggtagtcac caagagttaa tgcaggcgca
     3001 aggcttctac catcatctat tcaataaata aggagaatgt catgaatcct aatcttttta
     3061 gaagtgtcga gttttatcag agacgttacc ataactatgc gacagtgttc attatacctc
     3121 tttcattact atttactttc atcttgattt tctcccttgt tgccacaaaa gaaattactg
     3181 ttacttccca aggagaaatc acccctacaa gtgtcattgc atctattcag tcgaccagtg
     3241 ataatcctat ccttgctaat catttagtgg caaatcaagt agttgagaaa ggtgacttac
     3301 tcatcaaata ctctgaaaca atggaagaaa gtcagaaaac tgccttagca actcaattac
     3361 aaagacttga gaagcaaaaa gaaggacttg gaatcttgaa acaaagctta gaaaaagcga
     3421 ctgatctttt ttctagcgag gatgagtttg gctaccataa tacctttatg aattttacta
     3481 aacaatccca tgatattgaa ctgggtatct caaagactaa cactgaagtt tcaaatcaag
     3541 ctaatcttac caatagcagt tcatcagcca tcgaacaaga aattacaaaa gttcaacaac
     3601 aaattggaga atatcaagag ttgagagatg ctatcataaa taacagagca cgcttaccaa
     3661 ctggcaatcc gcaccagtca attttaaatc gttatcttat agcctctcaa ggacaaacac
     3721 aaggaacggc agaggagcca tttttatctc aaattaatca aagtattgca agtcttgaat
     3781 catctatcgc aagcctcaaa attcagcaag ctggtatcgg aagtgtagca acttatgata
     3841 atagtttagc aaccaaaatt gaagtactcc gcactcagtt tttacaaaca gcctcacagc
     3901 aacaactaac cgtggagaat caattaacag aattaaaagt acaactagat caagcgacac
     3961 agcgcttaga aaataatacc ttaaccgctc caagtaaagg tatcgttcat ctgaacagcg
     4021 aatttgaagg taaaaataga attccaactg gtacagaaat tgctcaaata ttccctgtca
     4081 tcacagatac aagagaagta ctaatcactt actacgtatc atctgactat ctccccttac
     4141 tagataaagg acaaactgta agattaaaac tggagaagat tggaaatcac ggcaccacca
     4201 tcatcggcca acttcagagt attgatcaaa ctcctaccag aacagagcaa ggcaatctct
     4261 ttaaattaac cgctcttgca aaactatcta acgaggatag taaactcatc caatatggct
     4321 tacaaggtcg cgtcactagt gtaactacaa agaaaacata ttttgattat ttcaaagata
     4381 aaattttaac ccattctgat taattttcag ataacactct ataactattt attatcttat
     4441 caaaaaggag aatcataaca tggataagaa acaaaaccta acttcatttc aagaactaac
     4501 aactaccgaa ctcaaccaaa ttataggtgg aggatggtgg gaagatttct tatatagatt
     4561 taatataatt gaacaaaaaa atacaaaagg attttatcag ccaatacaac tataaaaaaa
     4621 caagaccaag agaacgcact ctcggtctta ttttttcttc attctatatg tattacagta
     4681 agtacctgac gaaaaacgtg atcttggcag gtggtattga gactggtatt gggatgactt
     4741 tccacaattt tcataacggt atagagacca actcctctct cctccccttt agaacttgct
     4801 ccaaaggaga agatttcaga aatatcgatt ccctcttctt tgatggaatt ttcaatgata
     4861 aaggtctcct gtgctccatt tttaaaaaag gcaattgaaa catgaggttg acaggcttct
     4921 acactagctt caatagcgtt gtcacaaagg atagacacaa cggttagaaa atcaagtaga
     4981 ctcaccccct ctacctgaat ctcctctgga acttcgacat taaagacaat gttcttatct
     5041 ctagctttta taaattttcc agctaggaga cttttgaggg cacgatcccg aacattcacc
     5101 aatcggccaa ggtcatattt attgtcctgc aatttttcac tagaatcctt taagaccgag
     5161 tcgtagatct cttttatctg ctccatatcc tcctcttcaa tgcccagacg taagctagtc
     5221 aagaggttgg tgtagtcatg gcgaaaactc cgtacttcct tataaagctc ctctatatgc
     5281 cgactatagc gttccatatc tctatagcgc agggcctgct cttgttccaa tctctcatgg
     5341 agtttgtcct tcaaataggt atccaatttc ttgataatcc ccataaaaaa gagcaggtaa
     5401 aagactagga tgagatggcg aacagtcgtt gattgaatcc cctgttcata ttcaaagtaa
     5461 gacagatttt gtatcaccaa atagtaagcc cccattatcc agttaatctg agtcagggac
     5521 ttttgaaaat ctttatcgag aatccccttt ctcaagctag tgaaatcata gtccaaccat
     5581 ttcaaaaaag ctagagaaat gaagaaattg aaaattatta tacataacca aataaatgag
     5641 tagtcatcat atacttgccc ttgtcccaaa aatggaagca caaaatagga aacacctcta
     5701 taaaagagat tcactaatat cattggaaag agaccataaa agagaaggag ttttttagga
     5761 agttctctta acaataagaa agataagcct atgccgtaca agggttccat aaaataagat
     5821 aggtaaacat ttcctaccat atagccaagc attccaaaaa caacggccaa cagtatctta
     5881 aaaagaaagg ccttaaaaat cctctcaaaa gtgagactaa ttccatctac cttaaagaat
     5941 atgacaattt ttaatccgtg agtaacaagt gtatacaaca atatccaagc aacattcata
     6001 aactctccta gctcagtgta agttattaat agcctcagac acttccctga ccttataacg
     6061 cgcgattaga caacttccac cattgggaaa gaaaagcagt ttttctttct tatctaaatg
     6121 caccacattg gcaggattga tgagaaaaga gcgatggcac tgcaagagac gaggctcctg
     6181 cttgagaacc tcctctagac tcgctgtaaa ttccagcctg tctgtcttgg tatagagaat
     6241 aacacgatgg ggtcttgtgg acgtttcgag atagtaaacc tctttaaaag gatactggaa
     6301 ttgagcaaat tttgatttaa agtaaaagca atcttccgct agacttttac tgtcttgacc
     6361 attggcatag aggagggctg tctcgatacg agattcaaac tcctctgccg aaagggcctt
     6421 atcaatataa tccagagcag acacttggta gcgaaaggac aggggcataa actccgagtg
     6481 agtcgtcaca aagacaatca gggcatacgg atcccgatcc cgaatctttc tagccacttc
     6541 cagacccttc atctcctcat ttcgaatctc aatatccaaa aagaatagct gatgggcccc
     6601 cttctcatgc acctctgcca gcaattgatc tggcttacca aaaacttcaa aagaactcag
     6661 agtgatatga tgttccttca agagtttctc aatcgtcgtt tcaattctag tctgttggga
     6721 aaaatcatcc tctaaaacaa atattctcat cttcttactc tccctctttc aaccattttt
     6781 gacgaatttc tctatagcga cgtctggcat acttgacagc gtattgacct tcttctccga
     6841 gaaaaaggat tctttcttga aaatcaatcg attttaattt atcaagatta accaaacaat
     6901 ttcgatgaca tctcatcaag gtttccccac attggttctc aagattactt aaattttgaa
     6961 gcatattaaa actagcttct tctgtaacaa tctgtacggt atgggcttta gttggatgtg
     7021 tttggatata gtagatatcg tcgatgttta ctttatagac tgttttctgc gtctgaataa
     7081 tcatatgttt cattggattc tcctcctaag aaaagaataa cagaaaaggt ctagcccaag
     7141 cacacccaat cctaaacagt ctttgaaaac tcctaaaagg attattttct acaacatcat
     7201 gatgagctta caactatttt atcataaaat tcactcagcg caattcaaga catttcaatg
     7261 acaattaaag atttgaataa aaaaaaagaa ttaaaagtga taaactaaca gtatcaaaac
     7321 acagttgcca gaagtaagac tggcacccag attaaaggag gcattcccat gacagataca
     7381 gaccccatca aaagagctca tactttgatt actgacttaa acaaagccta ccaagcatgc
     7441 aaacaggcaa gcgctgacga cctccgcttt caggagcaat taaactctat tcttggtttt
     7501 ctagccaagg ctgaaacagt ggataatcga ttcttgattg aattggaaaa attttaccag
     7561 acttccagtc ttctcatggg actcagcgct cttgatccag atgctccaac tcgcgccgct
     7621 tggcgggcct atgaccgctt ccactttgac caagtcaaga ccaagttaat actcaatgaa
     7681 aatcaaagag caaactagga agctagccgc aagctgtact tgagtacggt aagacgacgc
     7741 tgacgtggtt tgaagagatt ttcgaagagt ataagtctct acggaccaac cattatcctg
     7801 tagtaacaaa aaagaagctg agacagactg aactcaactt cttttttagt gtcgtatcag
     7861 caatgttagt cctgcatctg acgttttacc tgataaggca aatacaagac ttgtaaaacc
     7921 aaaccagctc ccagtaaggc tagaagggct agtttttctt gaaaggtaat caacccaaca
     7981 actaattcca caagtaaaac aaaactggtc aatcctcgaa ctacctcctg taagcctttt
     8041 tccttttgcc ccttgtccag cggaaagagt tgggtcaaat actggtagtc aaaggcatga
     8101 tagagggcca gcaactggaa gagcaagagg tagttaaaga gaactaccac tgctgtcgca
     8161 atccaagctt gctcgataaa aacctgcgcc agtacggaaa gtaagagaag acgaagactg
     8221 agagcaaaga ggtcgccatt tcgcagataa gaacgcagat agagattttg ccaaatcttc
     8281 ccaggcacct tctgaacagc ctttaagata aagtccagat aggcacgacg cttaacgctg
     8341 tttgaaattc ccttgacctg cgtaaagagg gcaaagaaac gaagcaagac ttgcttacgc
     8401 ttgctttctt gagaaataac atagtcccaa tccagtccag tttcagtgaa aaatttgctg
     8461 gccttttgac gaaagtggaa atattttcct acccccaata aaagcacata gagcagaaaa
     8521 actggcaagc cataacccat tgctaaaaat aaaggcgcaa ataacagcaa gaaaagggtc
     8581 tgtacaaaga gccaaaagac tagggaaatg ccagtttgac gcttgagatg gagcttgatt
     8641 tcctcttctc caactaagag aaagagcttg tctggagcct ccatataggt ggcaattcct
     8701 ccccaaagta aaagtaaaac agacgtaatt cctacaaaca aaaggatagg ccaatgattt
     8761 tcaggaaaat gttgtaagag ttgactgtac tggtaggcta gaaagcccaa caggacaagc
     8821 aggaacaaga caaagtggtc attgagcaca tagcgcagat aaccaagaca ctccttacga
     8881 aaggcctgct ttctctttaa aaacaagtct ttcataggtc ctcctctttt gtcagagcca
     8941 agtaaatatc attcaaacta gcctcaggca tatcaaaggc ttcgcgtagt tgcaggagat
     9001 tgcctttggc acgcacctct cccttgtgaa gaatgacaaa ggcatcacac atcttctccg
     9061 ccgaatccag cacgtgggta ctcatgagaa tagacttgcc cttttgcttc tccacttcca
     9121 aaagctgaat caaatcagaa atagccagcg gatcaagacc aaggaaaggc tcatccacga
     9181 tgaaaagact tggatccgcc acaaaagcac agataatcat gaccttctgc ttcatccctt
     9241 ttgaaaaatg aacagggaac cagtctaatt tctgttccaa acggaacatt tttaacaagg
     9301 gctctactcg ttcgaaagcc actttttgct caataccgta agccatagca accgtttcga
     9361 tatgctctct gagggtcaat tcctcataca gactaggcgt ctcaggaatg tagccaatct
     9421 gcttgcggta gctagtcgca tctccttgca gagtcaggcc attgatattg atggagccac
     9481 tataaggtgc caacagaccg ataatctcat tgatcgtcgt tgatttccca gcaccattga
     9541 gaccaatcaa accgaccaac tgcccacttt caacagtaaa ggacacatct ttcaaaacag
     9601 gaacatgaac atagccacct gtcaggtttt taatttctaa catattttct ccaaatctgg
     9661 tataatgtag ctatattata tcaaaattca gtacagtaga ggtagatttt atgtcagatt
     9721 gcattttttg taaaatcatc gcaggggaaa ttcctgcttc aaaagtatat gaagatgagc
     9781 aggtccttgc ctttcttgat atctctcaag taacactagg acacaccttg gtcgtgccaa
     9841 aagaacacta tcgcaatctt ttggagatgg atgctacgaa cgccagccaa ctctttgccc
     9901 aagtaccaaa agtagctcaa aaagtcatga aagtcactaa ggctgctggt atgaatatca
     9961 tttccaactg tgaagaagtc gctggtcaaa cagtttttca tactcacgtt caccttgtac
    10021 ctcgctacag tgctgacgat gacctcaaga ttgattttat cgcccacgaa ccagactttg
    10081 acaaacttgc tcaagtcgct gaaaccatca aaaacgctta aggagttgct atgaaattat
    10141 ccaacctact gctatttgca ggagctgcag ccggaagtta tctggtcaca aaaaatcgcc
    10201 aaaccatcac agatgaagtc ttgaatacca ctgaccgcgt tcaagctatc aaggacgatg
    10261 tggatattat ccaaaacagc ctgcaaatca ttgaccagca aaaagaactt atcaaggaat
    10321 accaagaaga cttgacttac aagtttaagg tcttggaaaa ggatatccag actagactag
    10381 ctgtgataaa agaaatgcag ggaactgaag ataagtaaaa agagcccgac ggctcttttt
    10441 taaaacgtaa acaagttata gtgaattgaa tttagaatag cacatcatag tttctaaagc
    10501 attgttagag attactttaa aatcctctta tcaatttgtt catattctat ttcaatctac
    10561 tatatatatc ccatcaacta tgcatcataa tttaggtaac tcatactcaa taaaaatcaa
    10621 aaagcaaact agaaagctag gcacagactg ctcaaaacac cgttttaagg ttgtggatag
    10681 aactgacgaa gtcagtaacc atacccatga caagccgacg ctgacgtggt ttgaagaaat
    10741 ttttgaagag tatcattcac catttcacaa ctaaatcgaa gactttctgc cgtaatgaaa
    10801 acacctgaaa cagcttggtt tcggctatcc ggaaacttta agacttaggt tcaaagttta
    10861 ggtatggaac ttcgaaggag gtcgctaccg tccgtcatta cttaggaaag tcttaaaaaa
    10921 tctataaagt aaaaagagcc cgacagctct ttttgtttat actcaatgaa aatcaaaaag
    10981 caaactagga aactagccac gggctgctca aaacactgtt ttgaggttgt agatacgact
    11041 gacgaagtca gtcacatata tacggcaagg caacgctgac gtggtttgaa gagattttca
    11101 aagagtatta ttctccatca aaggcatctt taatatggtc aaagaagcct tttttctttg
    11161 gatttacttt caagtcacca gcagccgcga attctttcaa ggctactttt tggcggtcgt
    11221 tcaagcctgt cggtgttacg acattaacag taacgtattg gtcaccaact gcaccgccac
    11281 gaaggctcgg tgccccctta ctacgtaggc ggaatttctt accagtctga gttccctctg
    11341 gaataaccaa ttcaacatca ccgtgaacag ttggaatatc tactgtatca ccaagagccg
    11401 cttggacaaa gttgaggttg agattgtaga agatagtcgt tccttcacgt tcaaacttgt
    11461 cgctagcttc cacagaaact actacataca agtcaccata aggtccaccg ttaaagcctg
    11521 cttcaccttg accagcgagg cgaatttgtt gacctgtttc cacaccagca gggattttca
    11581 catgtacgct atgagcttgt ttctcatgac ctgttccatg acaggttgta catggatatt
    11641 tgatttcttt tccttggccg tgacagacat cacaggttac ttggcgacgc atcataccaa
    11701 gaggagtctg cgtatcgacg ttaatgacac cagcgccatg acagcgtcca caagtgactg
    11761 gacttgtccc tggcttagca ccagagccat tacatgtacg acagccagct tcacgatgat
    11821 acttaacttc cttctcagtt ccgaagatag cttcttcaaa ggtcaaattg acacgatact
    11881 ggagatcatc tccttggcga ggagcgtttg gattgcgcga agaaccgcct ccgccgaaga
    11941 aacttgagaa aatatcctca aaaccaccga agccacctgc cccattgaaa ccgccgaaac
    12001 caccatctcc accaaaacca ccattggcgc ctgcagcacc atactggtca taggcagcac
    12061 gtttttggtc gtcactcaaa gtctcatagg cttcttgaac ttccttgtac ttgtcctcag
    12121 caccaggctc cttgttgata tctgggtgat attttttgga aagcttacga taagcctttt
    12181 tgatttcgtc tgccgaagcg tttttggata cccccagacg atcataaaat tcagtattgt
    12241 tcataattca agatacaaag ggcgtcaaac ggacacagcc atctaggagt tttgacgacg
    12301 gacgcttatg tcctagaaaa aactatcttt ttggcacagt ccgtagcccg tgttcagtta
    12361 cgaacaccct tattcctttc tattgatgtt ctgaatcgaa ccaccattta ggtcggattc
    12421 aattcctttc ttttatattt agtaagaaat tctgaaaccc gtgttcagtt acgaacactc
    12481 tttgttcctt tctattgatg agacaaaacc caaacaaata agattccgtc cctttttatc
    12541 gaaaaacaga ggctgggttg caacctctgc aaataa
//
LOCUS       DAVLUM010000057        12440 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLUM010000057 DAVLUM010000000
VERSION     DAVLUM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.057"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            225..2516
                     /gene="pcrA"
                     /locus_tag="VYN42_001568"
     CDS             225..2516
                     /gene="pcrA"
                     /locus_tag="VYN42_001568"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1462620.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWNFANMMLDLREQLDHLSITELVESVLEKTGYVDILNTQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2559..3239
                     /gene="radC"
                     /locus_tag="VYN42_001569"
     CDS             2559..3239
                     /gene="radC"
                     /locus_tag="VYN42_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1462621.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3236..3925)
                     /locus_tag="VYN42_001570"
     CDS             complement(3236..3925)
                     /locus_tag="VYN42_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1462622.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKIIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3943..4584)
                     /locus_tag="VYN42_001571"
     CDS             complement(3943..4584)
                     /locus_tag="VYN42_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1462623.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDNHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4667..4882)
                     /locus_tag="VYN42_001572"
     CDS             complement(4667..4882)
                     /locus_tag="VYN42_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1462624.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4890..5237)
                     /locus_tag="VYN42_001573"
     CDS             complement(4890..5237)
                     /locus_tag="VYN42_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1462625.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5242..6357)
                     /locus_tag="VYN42_001574"
     CDS             complement(5242..6357)
                     /locus_tag="VYN42_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1462626.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIP
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6367..7326)
                     /locus_tag="VYN42_001575"
     CDS             complement(6367..7326)
                     /locus_tag="VYN42_001575"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1462627.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7439..8008)
                     /locus_tag="VYN42_001576"
     CDS             complement(7439..8008)
                     /locus_tag="VYN42_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1462628.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8136..8807
                     /locus_tag="VYN42_001577"
     CDS             8136..8807
                     /locus_tag="VYN42_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1462629.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8791..9609
                     /locus_tag="VYN42_001578"
     CDS             8791..9609
                     /locus_tag="VYN42_001578"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1462630.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9606..10502
                     /locus_tag="VYN42_001579"
     CDS             9606..10502
                     /locus_tag="VYN42_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1462631.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     DIRLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLDDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10546..11520
                     /gene="pta"
                     /locus_tag="VYN42_001580"
     CDS             10546..11520
                     /gene="pta"
                     /locus_tag="VYN42_001580"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1462632.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11861..12160)
                     /locus_tag="VYN42_001581"
     CDS             complement(11861..12160)
                     /locus_tag="VYN42_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1462633.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVIDPEDLETLSDTTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3597 a         2376 c         2666 g         3801 t
ORIGIN      
        1 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta ttgaggtatt
       61 gagctagttt atgaaaaaat tgggtgaaaa gtcgagtgtt ttagaaaccc acagtgtagt
      121 attctagttt caatccacta tattttgcta ctccccgtaa agtttctatt ttccctgatt
      181 tctgatataa tagaaatatt gacttcaaga gtaaggaaga gaagatgaac gcattattaa
      241 atggaatgaa tgaccgtcag gctgaggcgg tgcaaacgac agaaggtccc ttgctaatca
      301 tggcaggggc tggttctgga aagactcgtg ttttaaccca ccgtatcgct tatttgattg
      361 atgaaaagct ggtcaatcct tggaatatct tggccattac ctttaccaac aaggctgcgc
      421 gtgagatgaa agagcgtgct tatagcctca atccagctac tcaggactgt ctgattgcga
      481 ccttccactc catgtgtgtg cgtattttgc gtcgcgatgc ggaccatatt ggctacaatc
      541 gtaattttac aattgtggat cctggtgaac agcgaacgct catgaaacgt attctcaaac
      601 agttgaactt ggatcctaaa aaatggaatg aacgaactat tttggggacc atttccaatg
      661 ctaagaatga tttgattgat gatgttgctt atgctgccca agctggcgat atgtatacgc
      721 aaattgtggc ccagtgttat acagcctatc aaaaagaact tcgtcagtct gaatccgttg
      781 actttgatga tttgattatg ctgaccttgc gtctctttga tcaaaatcct gatgttttga
      841 cctactacca gcaaaaattc caatacatcc acgttgatga gtaccaagat accaaccacg
      901 ctcagtacca attggtcaaa ctcttggctt cccgttttaa aaatatctgt gtggttgggg
      961 atgcggacca gtctatctac ggttggcgtg gtgctgatat gcagaatatc ttggactttg
     1021 aaaaggatta ccccaaagcc aaggttgttt tgctggagga aaattaccgc tcaaccaaaa
     1081 ccattctcca agcggccaac gaggttatta aaaataataa aaatcgccgt cctaaaaatc
     1141 tctggactca aaacgctgat ggggagcaaa tcgtttacta tcgtgccgat gatgagctgg
     1201 atgaggctgt atttgtagcc agaaccatcg atgaacttag tcgcagtcaa aacttccttc
     1261 ataaggattt tgcagttctc tatcggacta atgcccagtc ccgtacaatt gaggaagccc
     1321 tgctcaagtc taacattcct tataccatgg ttggcggaac caaattctac agccgtaagg
     1381 aaattcgcga tattattgct tatctcaacc ttattgctaa tttgagtgac aatattagtt
     1441 ttgagcgtat tatcaacgag cctaaacgtg gaattggtct aggtacagtt gagaaaatcc
     1501 gtgattttgc aaatttgcaa aatatgtcta tgctggatgc ttctgctaat attatgttgt
     1561 ctggtatcaa gggtaaggca gcccaatcta tctggaattt tgccaatatg atgcttgatt
     1621 tgcgggagca gctagaccac ttaagcatta cagagttggt tgagtccgtc ctagaaaaaa
     1681 caggttatgt cgatattctt aacacccaag cgactctaga aagcaaggca agggttgaaa
     1741 atatcgaaga gtttctttct gttacgaaga actttgatga caccactgat gtgacagaag
     1801 aggaaactgg tctggacaaa ctgagtcgtt tcttaaatga cttggctttg attgccgaca
     1861 cagattcagg tagtcaggag acatcagaag tgaccttgat gaccctgcat gctgccaaag
     1921 gtctcgaatt tccagttgtc tttttgattg ggatggaaga aaatgtcttt ccacttagtc
     1981 gtgcgactga agatccagat gaattagaag aagagcgccg tctagcctat gtaggtatca
     2041 cgcgtgcaga gaaaattctc tatctgacca atgccaactc acgcttgctt tttggtcgta
     2101 ccaattataa ccgtccgact cgttttatta acgaaatcag ttcagactta cttgagtatc
     2161 aaggtctggc tcgtcctgca aatacaagct ttaaggcatc atatagcagt ggtagtattt
     2221 cctttggtca aggtatgagt ttggctcagg ctcttcaaga ccgtaaacgc ggtgctgccc
     2281 caaaatcaat ccagtcaagc ggtcttccat ttggtcaatt tacagctggc gcaaaatcag
     2341 catctagcga ggcaaattgg tccattggtg acattgctct ccacaagaaa tggggagagg
     2401 gaaccgttct ggaagtttca ggtagcggtg ctaggcagga attgaaaatc aatttcccag
     2461 aagtaggttt gaaaaaactt ttagccagtg tggctccaat tgagaaaaaa atctaatttt
     2521 ccatccttct cacgaataat aaagtgagga ggatttttat gtacagtatt tcattccaag
     2581 aagattcact attaccaaga gaaaggctgg ccaaggaagg agttgaagcg cttagtaacc
     2641 aagagttgct agctatttta ctcaggacag gaacacgtca agctagcgtt tttgaaattg
     2701 cccaaaaagt cttgaacaat ctttcaagcc taacggattt gaaaaaaatg accctgcagg
     2761 aattgcagag tttgtctggt attgggcgtg ttaaggccat agaattacaa gctatgattg
     2821 aactggggca tcgtattcac aaacacgaga ctcttgaaat ggaaagtatt ctcagcagtc
     2881 aaaagttggc caagaagatg cagcaggaat taggggataa aaaacaagag cacctggtgg
     2941 cactctatct caatactcaa aatcaaatca tccatcagca gaccattttt atcggttctg
     3001 taactcgtag tatcgctgaa ccgcgagaga ttctgcacta tgcaatcaag catatggcga
     3061 cttctcttat cttggtccac aatcatcctt caggagcggt agcgcctagc caaaatgatg
     3121 atcatgtcac taaacttgtt aaagaagcct gcgaactgat ggggattgtt ctcttggacc
     3181 atttgattgt ctctcattct aattacttta gttatcgtga aaagacagat ttaatctaaa
     3241 gttcattaac gacatagtca aagagtttct tatctttggg acgattttca aaaagaagtt
     3301 ctggatgcca ttggacaccg agaaaggcga catcatccgt actcatgaca gcctcaatga
     3361 taccatcttt aggatcatga gccacaactt ttaaatttgg tgctaagtcc ttgatgctct
     3421 ggtggtggaa ggagttgata tgagagattt ctccatagat ttcttggaga acggtatctg
     3481 gttctgtcac caagcgttga gttgtgtact caacagaaga atcctgccaa tggtcttcga
     3541 tatcttggta caaagttcca cccatggcaa cgttaaagag ttgggtacca cggcagacag
     3601 agaaaatggg ctttttctgt ttaatagctt ccttgatgag ggccagttcg aagatatctc
     3661 tttgaaggtg atagtcatcg ctatcaatga ttttgggttc gccataaaat tttggatcga
     3721 cattttgccc acctgtcaag atgagcttgt caatcaaact gatatagtgg caggccattt
     3781 cttgatcacc aatcggtagg atgatgggaa tccctccagc atctttaacg ccttcaacaa
     3841 agccttttgc tgcgtagctc atcatgatgt catcatctgg atgagttttt tcgtttcctg
     3901 taatcccaat aactggtttt ttcataaaat gattttcgct ttctaatcct cttttcgcat
     3961 gaagtagagg agggtttgga gttcacttgt caaatcgaca tactgaacga ccacgtcttt
     4021 tggtaaatgc agatggactg gtgaaaaact gagaattcct ttcacaccag catcaaccaa
     4081 gagattagca acctcttgtg acttgacact gggaacagtt aggatagcag tcttcacatc
     4141 agcatccttg attttatcct tgatctgaga aattccgtaa atgggaatcc cgtcaggagt
     4201 ttgggtaccg acttcaggat ggttatctag gtcaaaggcc atgataatct tcatcttgtt
     4261 acgttcgtgg aagcggtagt ggagaagggc atggcccata tttccaatac caaccagcat
     4321 gacattggtg atggagttat cattgagcaa atcggcaaaa aatgtcatta gttttttgac
     4381 atcatagcca aaaccacgac gaccaagttc accaaaatag gaaaaatcac gacgtacggt
     4441 cgctgaatca atcccaatgg cctctgcaat ttgcttagaa ttggcacgtt caatcttttc
     4501 tgcatgaaat ctcttaaaaa ttcgatagta gagagagagt ctttttgctg tagcttttgg
     4561 aatagcaaac tgtttatctt tcacaaaatc acaacctttc tattcttcta ttttatagaa
     4621 acattgtgaa aaaatcaaca aaaataagaa aaaactaaga aaaatcttag ttttgatgta
     4681 aaaaatctgc atgagataga aaacggtaga ggtctccgac cagaccctga taaacttttt
     4741 ggcccctaaa agtcagagaa gtcacataaa gtgtatctgg taaggttaca catcctgaca
     4801 aagtcaacat gagagcctca tgatcctcat acttgagagt acgctctaca tgatagcagt
     4861 ccttataggt cagttcaaac attttggctc tatctttccg attttgtaaa gacaccacgt
     4921 tctaccaagc tatccatgag gaagtagaat ttttcctgat gaatatggtg gtcttctgat
     4981 ttgaaaatat caactagacg aaggccaaac ttgtcagtga tattgatttt agcccctgta
     5041 agttccttgt taatgatgat tttgagttgg aagccttcac cgctgtttgg cactttttcc
     5101 aaaaggcgag tcagttcata gttaccaacc ttagtttcaa aaaaggtgtt atctttgagg
     5161 gtgaattttt taacagaagg gctaagagtg taatcgtaac gacaattttt taactgaatg
     5221 attttttcaa atgccatatg gctaacctcc gataatttct tttaaggttt ttgcgagggt
     5281 ttgtaggtct tcaacggtat tttgtggcga caaactgatg cgaagggatt ccttcaagcg
     5341 ttctgaattt gcgccataca tggcttcaag aacatggctg gattggacaa cgcctgcagt
     5401 acaggctgag ccagtagaga ttgaaattcc agctaaatct agccgaagga gtaagaggtc
     5461 atttttctga ccaggaaatc caatattgag aacataaggg agatgatgtt ttcctctatt
     5521 caggtaatac ggaatgccct ccagctctgc cagaaaggca gtttctagat tttgtacatg
     5581 ttgaaaatgt tcttcttgtt tttctaggtc ttcttttagg gctgcaacca tgcctacgat
     5641 ggcaggcaga ttttcagttc ctgcacgttt tttctgttcc tggtctccgc catgtagata
     5701 ggaatcaaag tccatgctag atgcgtagag aaaaccgatt cccttaggac catggaattt
     5761 gtgggcagaa gcagtgagaa aatcaatgcc caattcttct gaatgaattg ggattttacc
     5821 aatagcctga actgcatcaa catgataggc agcagggtgt tgcttgagta tttggccaat
     5881 ttcagcgatg ggcagtaggt ttcctgtctc attattggca aacatggtag aaaccaaaat
     5941 cgtatcgtca cgtaaagcct tttgaatttg ctgggctgtg atttcttgat tttctggctg
     6001 gataatggtt gcttcaaacc caaagtgttg aaccaagtaa tcaattgttt caaggacagc
     6061 atggtgctcg atggcagttg tgatgatatg ttttccttgt tcttggtgac gaagacagta
     6121 gccaatgatg gtagtattat tgccttcagt cccaccagaa gtgaaaaaga tatgttgagg
     6181 ttttgtcctt agtaactggg ctagttcctg acgggcttct cgcaagagtt tgccagcttg
     6241 acgaccatga ccatgaatac tagaaggatt tccgtgggtt tcttgcataa ccttggtcat
     6301 agctgaaata gcaactgctg acataggagt cgttgcagca ttgtccaaat aaatcaaaga
     6361 atcaccttat ttctttttat tgtaggcaaa gagtgggctg actggttttc tttcgtgaat
     6421 acggacgata gcatcgccaa ttaactcact agcagtgatg tagcatacat ttttaggagt
     6481 tttttctttt gttgctactg aatcagtcac aagaatttct ttaatattag tattgtcaag
     6541 aagctcagca gctccctcga cgaagagacc gtggctagaa acagcataaa tttctgtagc
     6601 tccttcacgt tcaacgattt tagaagcttc agagaaggta cgtcctgtat ttaaaatatc
     6661 atcaatcaag atagctttct taccttcaac atcaccaata atataacctt cgttacgagt
     6721 tgcatcgtct tgagggtagt cgataatggc gataggagca tcaagatatt cagccaggct
     6781 acgcgcacgt ttgacacctg aatttttagg gctaacgaca acaacatctg aaccaagcaa
     6841 tcctttatcg cagtaatgtt ttgcgaatag gggaacagtg aaaagattat ccactggaat
     6901 atcaaagaaa ccttgaacct gaacggcatg caaatcaaga gtcaggatac gatcaactcc
     6961 agccttaacc agcatattgg caactagttt tgctgtaagt ggctcacgag gacaagcaat
     7021 gcggtcttga cgtgcatagc caaaatatgg aaggacaacg ttgatactgt gggcacttgc
     7081 acgcacacaa gcatcgacca tgattaacaa ttccattagg tggttgttga cagggaaact
     7141 tgttgattgg atgatgtaaa catcataacc acggacactt tcttcgatat ttacttggat
     7201 ttctccgtct gaaaattgac gtgatgatag ttttccaagt gggacaccaa cagcttgggc
     7261 aattttctgt gcaatctctt ggttagagtt gagtgcgaaa agtttcatgt tttttctatc
     7321 tgacattata gaccgtcctc tgtaaacttt ataaatccta gttatattta ccttacatat
     7381 atgaactagg gtttgtgtat ttttatcttt tctattttac caaaaaatgg agattatttc
     7441 agctattttt catacttttg acaaatcgaa ccaattttga aggagctttt tgataggaaa
     7501 tctgattttt ctctaaaaat tgtcggaaat cctgtttgcc ttgctcatga ttttccactt
     7561 caagctccaa ttcgtaatct gttatatcaa agtatcggct ctgatccagt gccatgagac
     7621 caatagctgt tttcatttca tagcgaagcg ttgttagaca accaagaacc tgccagttct
     7681 tactttggat accatgtttc gccaattcat ccagtactag cccttgagga agttcttcct
     7741 tactcagata gttctcagca tcttttagtt gcaatttttg gttgtattcc atgtttccaa
     7801 cactctgcgg gactttgagt gtcaactcag cccagtcttc aaaggttcga atgcgcatag
     7861 cgactttctt ttctcgcagt tcaaaatcag gcgtgtcgat gtagtaattt gtttgaagaa
     7921 caggagtgac acctgtgaac tggtctttta gacgattgta ttcatctttt ttcaatagtg
     7981 ttttcaattc aatttctaaa tgtttcattt ttcttacctt tttttatcgt tgaaagcgga
     8041 tttatggtat aataagcatt gtatttattg tatatgaatc tggagaaaaa atcaaagata
     8101 tttttgacgg ataatatgag aacaagggag aatatatgac cttagaatgg gaagaatttc
     8161 tagatcctta cattcaagct gttggtgagt taaagattaa acttcgtggt attcgtaagc
     8221 aatatcgtaa gcaaaataag cattctccaa ttgagtttgt gaccggtcga gtcaagccaa
     8281 ttgagagcat caaagaaaaa atggctcgtc gtggcattac ttatgcgacc ttggaacacg
     8341 atttgcagga tattgctggc ttacgtgtga tggttcagtt tgtagatgac gtcaaggaag
     8401 tagtggatat tttgcacaag cgtcaggata tgcgaatcat acaggagcga gattacatta
     8461 ctcatagaaa agcatcaggc tatcgttcct atcatgtggt agtagaatat acggttgata
     8521 ccatcaatgg agctaagact attttggcag aaattcaaat tcgtactttg gccatgaatt
     8581 tctgggcaac gatagaacat tctctcaact acaagtacca aggggatttc ccagatgaga
     8641 ttaagaagcg actggaaatt acagctagaa tcgcccatca gttggatgaa gaaatgggtg
     8701 aaattcgtga tgatatccaa gaagcccagg cactttttga tcctttgagt agaaaattaa
     8761 atgacggtgt aggaaacagt gacgatacag atgaagaata caggtaaacg aattgatctg
     8821 atagccaata gaaaaccgca gagtcaaagg gttttgtatg aattgcgaga tcgtttgaag
     8881 agaaatcagt ttatactcaa tgataccaat ccggatattg tcatttccat tggcggggat
     8941 ggtatgctct tgtcggcctt tcataagtac gaaaatcagc ttgacaaggt ccgctttatc
     9001 ggtcttcata ctggacattt gggcttctat acagattatc gtgattttga gttggacaag
     9061 ctagtgacta atttgcagct agatactggg gcaagggttt cttaccctgt tctgaatgtg
     9121 aaggtctttc ttgaaaatgg tgaagttaag attttcagag cactcaacga agccagcatc
     9181 cgcaggtctg atcgaaccat ggtggcagat attgtaataa atggtgttcc ctttgaacgt
     9241 tttcgtggag acgggctaac agtttcgaca ccgactggta gtactgccta taacaagtct
     9301 cttggcggtg ctgttttaca ccctaccatt gaagctttgc aattaacgga aattgccagc
     9361 cttaataatc gtgtttatcg aacactgggc tcttccatta ttgtgcctaa gaaggataag
     9421 attgaactta ttccaacaag aaacgattat catactattt cggttgacaa tagcgtttat
     9481 tctttccgta atattgagcg tattgagtat caaatcgacc atcataagat tcactttgtc
     9541 gcgactccta gccataccag tttctggaac cgtgttaagg atgcctttat cggtgaggtg
     9601 gatgaatgag gtttgaattt atcgcagatg aacatgtcaa ggttaagacc tttttaaaaa
     9661 agcacgaggt ttctaaggga ttgctggcca agattaagtt tcgaggtgga gctattctgg
     9721 tcaataatca accgcaaaat gcaacgtatc tattggacgt tggagactac gttaccattg
     9781 acattcccgc tgagaaaggc tttgaaacct tggaggctat tgagcttcca ttagatattc
     9841 tctatgagga tgaccacttt ctagtcttga ataaacccta tggagtggct tctattccta
     9901 gtgtcaatca ctctaatacc attgccaatt ttatcaaggg ttactatgtc aagcaaaatt
     9961 atgaaaatca gcaggttcac attgttacca gactagatag ggacacttct ggcttgatgc
    10021 tctttgccaa gcacggttat gcccatgcac gattagacaa gcagttgcag aagaaatcta
    10081 tcgagaaacg ctactttgct ttggttaagg gagatggaca tttggagcca gaaggggaaa
    10141 ttattgctcc gattgcgcgt gatgaagact ccattattac cagacgggtg gctaaaggtg
    10201 gaaaatatgc ccatacttcc tacaagattg tagcttctta tggaaatatc cacttggtcg
    10261 acattcggct gcacactggt cgaacccacc aaattcgagt ccacttttct catattggtt
    10321 ttcctttgtt gggcgatgat ttgtacggtg gtagtctgga cgacggcatc caacgtcagg
    10381 ccctgcattg ccattaccta tccttttatc atccattttt agagcaagat ttgcagttag
    10441 aaagtccctt gccggatgat ttcagcaacc ttattaccca gttatcaact aatactctat
    10501 aaaaactgtt tcagagtata attattatct taaaggagaa aactcatgga agtttttgaa
    10561 agtctcaaag ccaaccttgt tggtaaaaat gctcgtatcg ttctccctga aggggaagag
    10621 ccacgtattc ttcaagcgac taaacgtttg gtaaaagaaa cagaagtgat tcctgttttg
    10681 cttggaaatc ctgaaaaaat taaaatttat cttgaaattg aaggaatcat ggatggttat
    10741 gaggtcatcg accctcaaca ttatcctcaa tttgaagaaa tggtttctgc cttggtggag
    10801 cgtcgcaagg gcaaaatgac tgaagaagat gtacgcaagg ttttggttga agatgtcaac
    10861 tactttggtg tgatgttggt ttacttgggc ttggttgatg gaatggtgtc aggagcgatt
    10921 cactcaacag cttcaacagt tcgtccagct ctacaaatca tcaaaactcg tccaaatgta
    10981 actcgtactt caggagcctt cctcatggtt cgtggtacgg aacgttacct atttggagac
    11041 tgtgccatta acatcaatcc agatgcagaa gccttggctg aaattgccat caactcagca
    11101 atcacagcta agatgtttgg catcgaacct aaaattgcca tgttgagcta ttctactaaa
    11161 ggttcagggt ttggtgaaag cgttgataag gtcgttgaag caactaaaat tgctcacgac
    11221 ttgcgtcctg accttgaaat cgatggtgag ttgcaatttg atgcagcctt tgttcctgaa
    11281 actgcagctc tgaaagctcc tggaagtacg gtagctggtc aagcaaatgt cttcatcttc
    11341 ccaggtatcg aggcaggaaa tatcggttac aagatggctg aacgcctggg tggctttgcg
    11401 gctgtaggac ctgttttgca aggtttaaac aagccagtta atgatctttc tcgtggatgt
    11461 aatgcagatg atgtttacaa gttgaccctc atcacagcag ctcaagcagt tcatcaatag
    11521 tgaaaactat aaagcgatat actatgctat actgtagtta tgaaactatg tacgaaaagc
    11581 actgccatta attcctgaga actaaattac tgattggtgt caaaaaggaa aacttccaag
    11641 cgatgatatt ctgtctatac acgacctata gaaatctgta atatgtatgt ccgtaaaacg
    11701 ataatttccc tttttgattt taaatgagta tgaaaagaga atttttcatg agaaaacgca
    11761 taatattaag tgtcttgaca cctgctatta tgcgtttttt ataatttttg cacctttctt
    11821 agcctttgtt atcgacaagt attgttctag ctccttgttt ttagaatggc aatttcccag
    11881 cgaaagcacc cagttttttc ttagtagttt catcgatttg ttcaagagca gagttgatgg
    11941 cttgaacggt cgtatcagaa agagtttcaa ggtcctctgg gtcaatgaca gctggattga
    12001 aatcaatgct gacaactttc ttatctccag ttaaggtcgc ttggacaaga tcttgagcag
    12061 atttgccaac aaattgcata gcagcaagtt cagcttggct ttgttccatt tgtttttgaa
    12121 gtttttgtgc ttgacgcatc atgttttgca tgttcatcat aagatttcta aagttccttt
    12181 catctcaagg ggataatcct tgttgttaac aagtgcctga ttttctctcc taattgttat
    12241 tagtagcata gccatcaagc ccaagtattg attttattat accatttttt taagacatag
    12301 tcttttattg gtgagagtta tttatgtcaa ggagtgatta gaaataaatt aaaataatga
    12361 tttttgctaa gagggctcta ttctagtttc atggaaatga ttttactaaa ggttcgtatg
    12421 ctttgtttgc aaacatgtta
//
LOCUS       DAVLUM010000058        11728 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLUM010000058 DAVLUM010000000
VERSION     DAVLUM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11728
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.058"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            102..1547
                     /gene="cps4A"
                     /locus_tag="VYN42_001582"
     CDS             102..1547
                     /gene="cps4A"
                     /locus_tag="VYN42_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV1462634.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYEVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMIDLVNTQLESGGKYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1549..2280
                     /locus_tag="VYN42_001583"
     CDS             1549..2280
                     /locus_tag="VYN42_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV1462635.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLVESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNIPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRVQYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            2289..2981
                     /gene="cpsC"
                     /locus_tag="VYN42_001584"
     CDS             2289..2981
                     /gene="cpsC"
                     /locus_tag="VYN42_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV1462636.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            2991..3674
                     /locus_tag="VYN42_001585"
     CDS             2991..3674
                     /locus_tag="VYN42_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1462637.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARTGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILVTAIGEVNKRDVQKAKQQLEQTEKLFLGVVLNKLDISVDKYGVY
                     GSYGNYRKE"
     gene            3683..4324
                     /locus_tag="VYN42_001586"
     CDS             3683..4324
                     /locus_tag="VYN42_001586"
                     /inference="COORDINATES: protein motif:HMM:NF014453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1462638.1"
                     /translation="MIKMYFVFKNILDRFLAFFLFITLIIIPIIPITILVIWIEDPGD
                     VFFFQDRIGLNGKSFKVIKFRSMYKDADQRIKKSIISGEIDRLNFKEHSQSMTTKVGK
                     VIRKLSIDELPQLVNIIKGDMAIVGPRPLQQFEITHHILTHKEMETTLKMSKRLSVKP
                     GLLCYWQVTPNKNDIPFSDRMNLDLLYIDNVSFKTDFLLILKGFYTVLMGNNN"
     gene            4326..5117
                     /locus_tag="VYN42_001587"
     CDS             4326..5117
                     /locus_tag="VYN42_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4422 domain-containing protein"
                     /protein_id="HEV1462639.1"
                     /translation="MKNIKILVATHKKYKMPSDSNMYLPIHVGCEGKKNLGFQGDNSE
                     ENISNLNPYYCELTGLFWAWKNLDCDYLGLVHYRRYFTKMTKRYNESINIDDVILNRF
                     EVEKLLENSDIIVPKRRKYYIETLYSHYDHTFDGSHLDLARKMIEMKNPEYLSSFDKV
                     MEQRSGYMFNMFIMKKELADDYFSWLFPILDSMYESMDLSGLTDFEARLFGRVSELLF
                     NVWLVKSNLTPKEVPFMYMEKVNLFKKGISFLMAKFFGKKYGQSF"
     gene            5137..6354
                     /locus_tag="VYN42_001588"
     CDS             5137..6354
                     /locus_tag="VYN42_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HEV1462640.1"
                     /translation="MKVVIKRKSLPEILALSALTIFLVVSILDVTFYVQYLPKVVYKI
                     LIAISLILLVIKELYKRKFDYRTIISLFATVLMYLLIGRVSTLNSNIAIGIIFIYALR
                     DIPFKSVAKTSLAVSVLILLFVITSAKLGVIINYLEISGTRVRSYLGFRYALFPSILM
                     MNIVAIVFYLKQNKIQYWQWLLLSLSAYWLYDETDSRLTFYSSCILLICSLLIRWIPE
                     LFSKFGYIFKAFKLTFIINAVVSFWVSFTYLNLSHSYINNLFLKLDYILGGRIYLMNK
                     SLNLYGFGLFGRPVEWNGNGLTIEGVRNYQTYLYVDNLYVQILQKFGLLALGIMLLVL
                     TLTLFKVIKRREWVLSFILILMSFHSMIDDLNLYLHYNIFWILLGSLIYPDYQFSDES
                     DEELGENSFEEII"
     gene            6450..7250
                     /locus_tag="VYN42_001589"
     CDS             6450..7250
                     /locus_tag="VYN42_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV1462641.1"
                     /translation="MSDIKIIQDKILIILKEFISICEENNLTYYALGGTLLGAVRHKG
                     FIPWDDDIDIGMSREDYEKFKILAPDLLPSNLKIVNNPLNLDITQLVDKNVIVKIANS
                     ENNVFIDIFPLDGYPEKGFFAAKLHSFRLLFQRMLCKISVLDQLEDKDRGTVENLIVK
                     ISKMLRIQKVLPKDTLVENLHKVIQKYDFKTSRYVGNVLGRYREREIVPKEYFKEPVS
                     LIFEDTMINCPTKYKEYLSEIYGDYMKLPSVEDRVAHNIELISVGDAE"
     gene            7266..8372
                     /locus_tag="VYN42_001590"
     CDS             7266..8372
                     /locus_tag="VYN42_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1462642.1"
                     /translation="MGKKICIVKWILDDSGGGERVAVSLANELTKKYEVHLIGITTKQ
                     SDLFFKINSQVRYSNFFDHRVRLSKNILKISKMLRKYFIDNEIEVGFGIGISANVFLS
                     LAGIGTQTKVVLCDHTNSITDNREFSQKFQRYVGTKLADKIITLTQEDRENYIKKYGV
                     PEERICYIYNWKEAALSDVSYNKKSTKIVTVGRFDYQKGYDYLIQVAKKVLEKRADWT
                     WEIYGSGNQDEVEKIRDLINENDLQDRLVIKGLEKNQDLIYGDKGIYVMTSRYEGLPL
                     VLLEAQQYNLPIASFSCPTGPNEIVEDGVNGYLVECYDVEAMSNRLLELMNDKELRNR
                     FSSHAKDNIEKFNKDRIIHQWIDLIEEVSGGGNV"
     gene            8365..9381
                     /locus_tag="VYN42_001591"
     CDS             8365..9381
                     /locus_tag="VYN42_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1462643.1"
                     /translation="MSNKILTITVPTYNIENYIGKCIESFKAVNPTYYSDFEVLIIND
                     GSTDNSVQVVKDLMEGSTLDLRIITKENGGHGSTINRGIKEASGKYFKVIDGDDWINV
                     PEFESLLDKLREINTDLVISDYTEQHVYNNSTIFKEFSSYLIPNQETRGIPSKWTPMH
                     ALVYKTSILKDNAITISENTFYVDQEYTMLPLQFVENYIYFKLDIYQYFLGRADQSMN
                     IDIMRKRADHHERVTKRILDLYKESYTQKPEIEKVVSDSLQYLVNKQNILYVMNEELD
                     KVYELFSYSEKSGFKFKFETKTKTSNLLYVNYKTKYLFNLVIKNLVKRKANSLEKEFQ
                     EKGF"
     gene            9486..10901
                     /locus_tag="VYN42_001592"
     CDS             9486..10901
                     /locus_tag="VYN42_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003009066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HEV1462644.1"
                     /translation="MKVLKNYAYNLSYQLLIIILPIITTPYVTRIFSSDNLGTYGYFN
                     SIVTYFLLLATLGIGNYGTKEISGNRKAIHQNFWGIYSIQLGASLFSTFLYVIVCLIL
                     PAMQNTVAYILGLSLFSKGLDISWLFQGLEDFRKITVRNITVKVIGVTSIFLFVKSAS
                     DLYLYVFLLTIFELLGQLSMWVPAREFIGKPHFDWLYAKQHLKPVILLFLPQVAISLY
                     VTLDSTMLGSLASIRDVGIYDQSLKLVKILLTLVTSLGSVMLPRVSNLLSSGDHKAVN
                     KMHEISFLIYNLVIFPIMAGMLIVNDDFVTFFLGQDFQEARYAIAIMIFRMFFIGWTN
                     IMGIQILIPHNKNKEFMLSTIIPAIVSVGLNLLLLPKLGYIGAAIVSVLTEALVWAIQ
                     LYYTRTYLKDVLIIRTMIKIILASAIMYSVLLVSKTYIHFSPTINVLVFVVLGGIIYL
                     FSVLSLKVIDVIELKQVIRKN"
     gene            10903..>11728
                     /locus_tag="VYN42_001593"
     CDS             10903..>11728
                     /locus_tag="VYN42_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEV1462645.1"
                     /translation="MHKFKDINLDLLKVIACVGVVLLHTEMGGFKETGSWNFSTYLYY
                     LGTYSIPLFFIVNGYLLLGKKEITYSYILQKVKWILITVLSWTLIVWLFKRDFSVNPI
                     KKLIGSLVQKGYFFQFWFFGALILIYICLPVLKQFLNSKRSYLYFLSVLLVIGLIFEL
                     TNIVLQMPIQAYVIQTFRLWTWLFYYILGGFISQFDKNTIKNGFKRWMKVIAVLLLLV
                     SPFILFFIAKTTYYNFFAEYFYDILLVKVVSVGIFLTIFSLVLNENSNKWIIFLSNQ"
BASE COUNT         3927 a         1621 c         2252 g         3928 t
ORIGIN      
        1 acattcgaat tacacaagat gcagatagtg aaaataaagg tgtagacatt accgtaaaaa
       61 agtgatataa tcgtatgatg ttcaaggtat aggtgttaat catgagtaga cgttttaaaa
      121 aatcaggttc acagaaagtg aagcgaagtg ttaatatcgt tttgctgact atttatttat
      181 tattagtttg ttttttattg ttcttaatct ttaagtacaa tatccttgct tttagatatc
      241 ttaatctagt ggtaactgcg ttagtcctac tagttgcctt ggtagggcta ctcttgatta
      301 tctataaaaa agctgaaaaa tttactattt ttctgttgct gttctctatc cttgtcagct
      361 ctgtgtcgct ctttgcagta cagcagtttg ttggactgac caatcgttta aatgcgactt
      421 ctaattactc agaatattca atcagtgtcg ctgttttagc agatagtgat atcgaaaatg
      481 ttacgcaact gacgagtgtg acagcaccga ctgggactga taatgaaaat attcaaaaac
      541 tactagctga tatcaagtca agtcagaata ccgatttgac ggtcaaccag agttcgtctt
      601 acttggcagc ttacaagagt ttgattgcag gggagactaa ggccattgtc ctaaatagtg
      661 tctttgaaaa catcatcgag tcagagtatc cagactacgc atcgaagata aagaagattt
      721 ataccaaggg attcactaaa aaagtagaag ctcctaagac gtctaagaat cagtctttca
      781 atatctatgt tagtggaatt gacacctatg gccctattag ttcggtgtcg cgatcagatg
      841 tcaatatcct gatgactgtc aatcgagata ccaagaaaat cctcttgacc acaacgccac
      901 gtgatgccta tgtaccaatc gcagatggtg gaaataatca aaaagataaa ttaacccatg
      961 cgggcattta tggagttgat tcgtccattc acaccttaga aaatctctat gaagtggata
     1021 tcaattacta tgtgcgattg aacttcactt cgtttttgaa attgattgat ttgttgggtg
     1081 gaattgatgt ttataatgat caagaattta ctgcccatac gaatggaaag tattaccctg
     1141 caggcaatgt tcatcttgat tcagaacagg ctctcggttt tgttcgtgag cgctactcac
     1201 tagcagatgg cgatcgtgac cgtgggcgca atcaacaaaa ggtcattgtg gctatccttc
     1261 aaaaattaac gtcaaccgaa gcgctgaaaa attatagtac gatcattaat agcttgcaag
     1321 attctatcca aacaaatatg ccacttgaga ctatgataga tttagtgaat actcagttgg
     1381 aaagtggagg gaagtataaa gtaaattctc aagatttaaa aggtacaggt cggatggatc
     1441 ttccttctta tgcaatgcca gacagtaacc tctatgtgat ggaaatagat gatagtagtt
     1501 tagctgtagt taaagcagct atacaggatg tgatggaggg tagatgaaat gatagatatc
     1561 cattcgcaca tcgtctttga tgtagatgat ggtcccaagt caagggagga aagcaaggct
     1621 ctcttggtag aatcctacag acagggggtg cgaaccattg tctctacctc tcaccgtcgc
     1681 aagggcatgt ttgaaactcc ggaagagaag atagcagaaa actttcttca ggttcgggaa
     1741 atagctaagg aagtggcgag tgacttggtc attgcttacg gggctgaaat ttactacaca
     1801 ccagatgttc tggataagct ggaaaaaaag cggattccga ccctcaatga tagtcgttat
     1861 gccttgatag agtttagtat gaacattcct tatcgcgata ttcatagcgc tttgagcaag
     1921 atcttgatgt tgggaattac tccagtcatt gcccacatcg agcgctatga tgctcttgaa
     1981 aataatgaaa aacgcgttcg ggaactgatc gatatgggct gttacacgca agtaaatagt
     2041 tcacatgtcc tcaaacccaa actttttggc gaacgttata aattcatgaa aaaaagagtt
     2101 cagtattttt tggaacgtga tttagttcat gtagttgcaa gtgacatgca caatttagac
     2161 agtagacctc catatatgca acaggcatat gatatcattg ctaagaaata tggagcgaaa
     2221 aaagcgaaag aattttttgt agataatccc agaaaaatta taatggatca attaatttag
     2281 gagaaaatat gaaggaacaa aacactttgg aaatcgatgt attgcaacta ttcagggctt
     2341 tatggaaaag aaagttggtc attttattag tggcaattat aacttcttca gttgcttttg
     2401 cctacagtac ttttgttatc aaacctgagt ttactagtac gactcggatt tatgtagtta
     2461 accgtaatca ggaagagaag tctggtttaa ccaatcaaga cttgcaggca ggatcatact
     2521 tggttaaaga ctatcgtgaa attatcctat cgcaggatgt tttggaggaa gttatttctg
     2581 atttgaaact agatttgacg ccaaaaggtt tggctaataa aattaaagta acagtaccag
     2641 ttgatacccg tattgtctct gtctcagtta atgatcgagt tcctgaagag gcaagccgta
     2701 tcgctaactc tttgagagaa gtagctgctc aaaaaattat cagtattact cgtgtttctg
     2761 atgtgacaac actggaggag gcaagaccgg cgatatcacc atcttcgcca aatattaaac
     2821 gcaatacact aattggtttt ttggcagggg ggattggaac tagtgttata gttcttcttc
     2881 ttgaactttt ggacactcat gtgaaacgtc cggaagatat cgaagataca ctgcagatga
     2941 cacttttggg agttgtacca aacttgagta agttgaaata ggagagagga atgccgacat
     3001 tagaaatagc acaaaaaaaa ctggagttca ttaagaaggc agaagaatat tacaatgcct
     3061 tgtgtacaaa tatacagttg agcggagata aactaaaagt aatttccgtt acttctgtta
     3121 accctgggga aggaaaaaca actacttccg taaatatagc aaggtcgttt gcgcgtacag
     3181 gctataaaac tcttttgatt gatggcgata ctcgaaattc agttatatca ggagttttta
     3241 aatcgcgtga aaaaattaca gggctaacag aatttttatc tgggacagct gatttatctc
     3301 acggtttatg tgatacaaat attgaaaatt tatttgtaat tcaatcggga tctgtatcac
     3361 caaaccctac agccttgtta caaagtaaaa attttaatga tatgattgaa acattgcgta
     3421 aatattttga ttatatcatt gttgatacac cacctattgg aattgttatt gatgcggcaa
     3481 ttatcactca aaagtgtgat gcgtccatct tggtaacagc aataggtgag gtgaataaac
     3541 gtgatgtcca aaaagcgaaa caacaattag aacaaacaga gaaactgttc ctaggagttg
     3601 ttttaaataa attggatatc tcggttgata agtatggagt ttacggttcc tatggaaatt
     3661 ataggaagga ataacggagt aattgataaa aatgtatttt gtttttaaaa atattttaga
     3721 tagatttttg gcgtttttcc tatttatcac actgataatc ataccgatta ttccgataac
     3781 aattctggtt atttggatag aagatccagg agatgtgttt ttctttcaag atagaattgg
     3841 tttaaatggg aagagcttta aagtaataaa gtttcggagc atgtataaag atgctgatca
     3901 aaggataaag aaaagtatta ttagtggtga aattgatcgt ctaaatttta aagaacattc
     3961 tcaaagtatg actacaaaag tcggtaaagt gatacgaaaa ctttcaattg atgaattacc
     4021 tcaattagtg aatattataa aaggtgatat ggctatagtg ggacctcgtc cattacaaca
     4081 atttgaaata actcatcata ttcttaccca taaagaaatg gagactactt taaagatgtc
     4141 taaaagattg tctgtgaaac ctggtttgct ttgttattgg caagttacgc cgaataaaaa
     4201 tgacattcct tttagtgata gaatgaatct agatttatta tacattgata atgtatcttt
     4261 caagactgat ttcttgctta ttttgaaggg attttataca gttttaatgg gtaataacaa
     4321 ttaacatgaa aaatataaaa atattagtag caacacataa aaaatataaa atgcccagtg
     4381 attcaaatat gtatctacca attcatgtag gatgtgaagg aaagaaaaat ttaggatttc
     4441 aaggtgacaa ttcagaagaa aatatttcta atttaaatcc ttattattgt gaattaactg
     4501 gcttgttttg ggcttggaaa aacttagatt gtgattatct gggtttagta cattatcgtc
     4561 gttattttac taaaatgaca aaaaggtaca atgaatcaat aaatatcgat gatgtaattt
     4621 taaataggtt tgaagttgag aaattgttag agaactcaga tatcattgtt cctaaaagaa
     4681 gaaaatatta tattgaaact ctttattctc attacgacca tacttttgat ggttctcatt
     4741 tagatctagc tagaaaaatg attgaaatga agaatccaga atatctctct agttttgata
     4801 aggtaatgga acaaagaagc gggtacatgt ttaacatgtt cattatgaaa aaagaactgg
     4861 cagacgatta tttttcttgg ctgtttccta tcttggatag tatgtatgaa agtatggatt
     4921 tatcagggtt aactgatttt gaagctagat tatttggaag agtaagtgag ttgttattta
     4981 acgtatggtt ggtgaagagc aatttaactc caaaggaagt gccgtttatg tatatggaaa
     5041 aagttaactt atttaaaaaa gggatttcat ttttgatggc gaaatttttc ggaaagaaat
     5101 atggacagag tttttagtta ggaataaaaa atagtgatga aagtagtaat aaaaagaaag
     5161 tctttgccag agattttagc tcttagtgca ctaactatat ttttagttgt gtcaatttta
     5221 gatgtgactt tttatgttca gtatcttcca aaagttgttt ataagatact gatagctatt
     5281 tcgcttattc tgctagttat aaaagagttg tacaaaagaa agtttgatta tagaactatc
     5341 ataagtctat ttgctacagt tttgatgtat ctccttatag ggagggtgag tactcttaac
     5401 tctaatattg caataggaat tattttcatt tatgctttac gcgatattcc ttttaaaagc
     5461 gtggcaaaaa cttctttagc agtaagtgta ctcatattac tgtttgttat aactagcgca
     5521 aaattgggag ttattataaa ttatttagag atttctggga ctcgagtccg tagttattta
     5581 ggatttaggt acgcactatt cccatctatc ttgatgatga acatagtcgc tattgtattt
     5641 tatttaaagc aaaataaaat acaatattgg caatggttat tgttatcttt atctgcttat
     5701 tggctgtatg atgaaacgga ttctcgatta acattttata gttcctgtat attgttgata
     5761 tgcagtttat taataagatg gatcccagaa ctattctcta agttcggata tatatttaaa
     5821 gcttttaaac tcacctttat tataaatgca gttgttagtt tttgggtctc ctttacctat
     5881 ctcaatttga gtcattctta tatcaataat ctttttttaa aattagacta tatattaggt
     5941 ggtcgtatat acttgatgaa taaatcgttg aatttgtatg gttttggatt attcggacga
     6001 ccagttgaat ggaatggaaa tggtctgacc attgaaggag ttagaaacta tcagacctat
     6061 ctgtatgttg ataatttgta tgttcaaatt ttacaaaaat ttggtttact cgctctagga
     6121 ataatgctcc tagtcctaac tttaaccttg tttaaagtga ttaagagacg cgaatgggtt
     6181 ctgtctttta ttttgatatt gatgagtttt cattccatga ttgatgattt gaatttgtac
     6241 cttcattaca atattttttg gatattatta ggtagtttaa tctaccccga ttatcaattt
     6301 tctgatgaaa gtgatgaaga gttaggggaa aattcttttg aagaaattat atagtgaaat
     6361 gctaagaaat atttgagaag aactcacaag agtatagctg agaagacagt tgtatatcga
     6421 gttttgctgt ttttatatag gagggaagta tgtcggatat aaaaatcatt caagataaga
     6481 ttttaattat cttaaaagag tttattagta tttgtgaaga aaataacctg acctactatg
     6541 ctctaggtgg gaccttgttg ggcgcggtac gtcataaagg attcatacct tgggatgacg
     6601 atattgatat cggtatgtca agagaagatt atgaaaagtt taaaatacta gccccagacc
     6661 tgttaccaag taatttaaaa atagttaata atccacttaa tcttgatata actcagttag
     6721 tagataaaaa tgttattgtt aaaattgcga attcggaaaa caatgtgttt attgacattt
     6781 ttcctctaga tggttatcca gaaaaaggat tttttgcagc taaattgcat agttttaggc
     6841 tattgtttca aagaatgctt tgtaaaatat cagttttaga ccagcttgaa gataaagacc
     6901 gtggcactgt ggagaatctt atagttaaaa tatcgaaaat gctaagaatc caaaaagtac
     6961 ttcctaagga tacattggta gaaaatctgc ataaagttat tcaaaaatat gattttaaaa
     7021 cttctcgtta cgtcggtaat gttctaggta gatataggga gagagaaata gttccgaaag
     7081 agtattttaa agaacctgtt tctcttattt ttgaggatac gatgataaac tgtccgacaa
     7141 agtacaagga atatttaagc gaaatctacg gtgattacat gaaattacca tcagtagaag
     7201 atagagtagc acataatata gaacttatat cagtaggtga tgcagagtga agggtaggat
     7261 agaaattggg aaaaaaaata tgtattgtga aatggatttt ggatgattct ggtggcggtg
     7321 agcgagttgc tgtatctttg gcaaacgaac ttacaaaaaa gtatgaagtt catttaattg
     7381 gaattacaac aaagcaatcg gacctgttct ttaaaatcaa ttcccaagta agatactcca
     7441 atttttttga ccatagagta cgcttgtcta agaatattct aaaaatctca aaaatgttaa
     7501 gaaaatattt catagataat gaaatagagg ttggttttgg gatagggata tctgctaatg
     7561 tatttttatc tttggcagga ataggaactc aaactaaagt agttttgtgt gatcatacca
     7621 attcgattac ggataataga gaattttctc agaaattcca aagatatgtt gggacaaagt
     7681 tggcagacaa gattatcact ctcactcaag aagaccgtga aaattatata aaaaaatacg
     7741 gtgttcctga ggaaagaatt tgctacatct ataattggaa agaggctgct ctttcagatg
     7801 tatcttataa taaaaaatca actaaaattg tgactgttgg ccgttttgat tatcaaaaag
     7861 gctatgatta tctcattcaa gtcgcgaaaa aagtgttaga gaaaagggct gactggactt
     7921 gggaaatcta cggttccggc aatcaagatg aagtagagaa aatcagagat ttaatcaacg
     7981 aaaatgattt acaggatagg ttagtcataa aaggactcga aaaaaatcaa gatttgattt
     8041 atggagataa agggatttat gtcatgactt ctcgctatga aggtctacct ttagtcctgc
     8101 tggaagcaca acaatataat cttcctatag ctagctttag ttgtccgaca ggaccgaacg
     8161 aaattgttga agatggagtt aatggctatc tggttgagtg ttatgatgta gaagcgatgt
     8221 ctaatagatt attagaacta atgaatgata aggagctaag aaatcgtttt tcatctcatg
     8281 caaaagataa cattgaaaaa tttaataaag accgaattat acatcagtgg atagatttga
     8341 tagaagaagt atctgggggg ggaaatgtct aataaaatac tgacgattac tgtgccaacc
     8401 tataatattg aaaactatat tggtaaatgc atagaatcat ttaaagctgt aaatcctacc
     8461 tattacagtg attttgaagt gttaatcatt aatgacggaa gtactgataa ttctgtacaa
     8521 gttgttaagg atttaatgga aggtagcact ttagatttaa gaattatcac aaaagaaaat
     8581 gggggccatg gctcaactat taatcgcggg attaaagaag ctagtggaaa atattttaag
     8641 gtcattgatg gggatgattg gatcaatgtt ccagaatttg aaagcttatt ggataagtta
     8701 agagagatta acactgattt agtgatttct gactatacag agcagcatgt atataataat
     8761 agcactattt ttaaagaatt ctcttcttat ctaattccaa atcaagagac aagaggtatt
     8821 cctagcaagt ggacacctat gcatgccctg gtctataaaa caagtatctt gaaggataat
     8881 gctattacga ttagtgaaaa tacattttat gtcgaccaag agtatacaat gctccctctt
     8941 caatttgtag aaaattatat ttattttaag ttggatattt atcagtactt cttgggaaga
     9001 gctgatcaga gtatgaatat tgatataatg agaaagagag cagatcatca tgagagagta
     9061 acgaaacgaa tcttagactt atataaagag agttatacac aaaagccaga aatagaaaag
     9121 gttgtcagtg actctttgca gtatctggtt aataagcaaa atattttgta tgttatgaat
     9181 gaggaacttg ataaggtata tgaactgttt tcatattctg agaaaagtgg attcaaattt
     9241 aaatttgaaa caaaaacaaa gacttcaaat ttactttatg tcaattataa aacgaagtat
     9301 ctttttaacc ttgttattaa aaatctagtt aaaagaaaag caaacagtct agaaaaagaa
     9361 tttcaagaga agggattttg atgaaatatg tcaggaagta aaacaaatca tcaatttttt
     9421 ctgaaggaat tcataacaaa attaactaca ctgtataaga ctgtattcaa gtggagtgtg
     9481 cttgtatgaa agtacttaaa aactacgctt acaatctttc atatcagtta ctaatcataa
     9541 tcttaccgat tattaccact ccctacgtta ctaggatttt tagttcggat aatctaggga
     9601 cttatggtta ttttaactca attgtaacct attttctttt gctggctact ttaggaatag
     9661 gaaattatgg aacaaaagag atttcaggta ataggaaagc tatccatcag aatttttggg
     9721 gtatttatag tatacaactg ggagcatctc tattctccac tttcctttat gttattgtct
     9781 gtctaatttt accagctatg caaaatactg tagcctatat tttaggctta agtttgtttt
     9841 ctaaaggttt agatatttct tggttatttc aaggtttaga ggattttcgg aaaattacag
     9901 taagaaatat aactgtgaaa gtcattgggg taacctcgat tttcttattt gtaaaatcag
     9961 ctagcgacct ctacctttat gtttttcttt taacgatatt tgagttatta gggcaactta
    10021 gtatgtgggt accagctcgg gaatttattg ggaaaccgca ctttgactgg ttgtatgcta
    10081 aacaacattt gaagccagtt atcttattat ttttaccaca ggtcgctata tcgctttatg
    10141 tgactttaga tagtactatg cttggttctc tagcctcaat aagagatgtt ggaatttatg
    10201 atcaatctct gaaacttgtc aaaatattat taacattagt aacttcatta ggaagtgtca
    10261 tgttgcctag agtttcaaat cttttatcct caggggatca taaagcagtc aacaaaatgc
    10321 atgagatatc atttttaatt tataatttgg ttattttccc cattatggca ggaatgctaa
    10381 ttgtaaatga tgactttgta acctttttcc tcgggcaaga ttttcaagag gcacgttatg
    10441 cgatagcaat tatgattttt agaatgttct ttattggttg gaccaatatt atggggattc
    10501 aaattttgat acctcataat aaaaataaag aatttatgct gtcaacaata attcctgcta
    10561 ttgttagtgt aggcttaaat cttctcttgc ttccaaagct gggctatata ggagcagcaa
    10621 ttgtttctgt cttaacagag gcgctagtat gggctattca attgtactat actcgtacat
    10681 acttaaaaga tgttctgatt attagaacta tgataaaaat tattctagcc tcagctatca
    10741 tgtatagcgt tttgctagtt tctaagacat acatacattt ttccccaact ataaatgttt
    10801 tggtatttgt ggtgttaggt ggaatcattt atcttttttc agttttatct ctaaaagtga
    10861 tagatgtgat agaattaaaa caagtaatta ggaaaaatta gaatgcataa atttaaagat
    10921 attaacttgg atttactaaa agtaattgca tgtgttggag ttgttttact ccatacagag
    10981 atggggggat ttaaagagac aggttcatgg aatttttcga catatttata ctacttagga
    11041 acctattcta tccctctatt ttttatagtt aatggttatt tattgttagg gaagaaagag
    11101 attacctatt cctacatatt acagaaagta aaatggattc taataacagt gctgtcatgg
    11161 acccttatag tttggctatt taaacgggat ttttcagtta atccaataaa aaaacttata
    11221 ggatcattgg tgcaaaaagg ttatttcttt cagttttggt tttttggtgc gcttatactt
    11281 atttatatat gtctccccgt tttgaaacaa tttcttaatt caaaaagaag ttatttatac
    11341 tttttatctg tattgctagt tattggtttg atttttgagt taacaaatat tgtgcttcaa
    11401 atgccaatac aagcatatgt aatacaaact tttagattat ggacttggct tttctattat
    11461 attttagggg gctttatatc tcagtttgat aaaaatacca tcaaaaatgg gtttaagaga
    11521 tggatgaaag taattgcagt acttttatta ttagtttcgc catttatatt atttttcata
    11581 gcaaagacca cttactataa tttttttgct gaatattttt atgatatttt attagtaaaa
    11641 gttgtaagcg tagggatttt tctaactatt ttctcacttg tattgaatga aaatagcaac
    11701 aaatggatta tttttctttc taatcaaa
//
LOCUS       DAVLUM010000059        11398 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLUM010000059 DAVLUM010000000
VERSION     DAVLUM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.059"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            14..163
                     /gene="blpO"
                     /locus_tag="VYN42_001594"
     CDS             14..163
                     /gene="blpO"
                     /locus_tag="VYN42_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1462646.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            267..386
                     /locus_tag="VYN42_001595"
     CDS             267..386
                     /locus_tag="VYN42_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1462647.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            854..1225
                     /locus_tag="VYN42_001596"
     CDS             854..1225
                     /locus_tag="VYN42_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462648.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            1854..2237
                     /locus_tag="VYN42_001597"
     CDS             1854..2237
                     /locus_tag="VYN42_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1462649.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2289..2978
                     /locus_tag="VYN42_001598"
     CDS             2289..2978
                     /locus_tag="VYN42_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462650.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3020..3268
                     /locus_tag="VYN42_001599"
     CDS             3020..3268
                     /locus_tag="VYN42_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462651.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLDLKNDV"
     gene            3298..3909
                     /locus_tag="VYN42_001600"
     CDS             3298..3909
                     /locus_tag="VYN42_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462652.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4070..4864
                     /locus_tag="VYN42_001601"
     CDS             4070..4864
                     /locus_tag="VYN42_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1462653.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            4861..5496
                     /gene="trmB"
                     /locus_tag="VYN42_001602"
     CDS             4861..5496
                     /gene="trmB"
                     /locus_tag="VYN42_001602"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1462654.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            5622..6101
                     /gene="rimP"
                     /locus_tag="VYN42_001603"
     CDS             5622..6101
                     /gene="rimP"
                     /locus_tag="VYN42_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1462655.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6145..7281
                     /gene="nusA"
                     /locus_tag="VYN42_001604"
     CDS             6145..7281
                     /gene="nusA"
                     /locus_tag="VYN42_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1462656.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7303..7596
                     /locus_tag="VYN42_001605"
     CDS             7303..7596
                     /locus_tag="VYN42_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1462657.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7589..7888
                     /locus_tag="VYN42_001606"
     CDS             7589..7888
                     /locus_tag="VYN42_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1462658.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            7905..10697
                     /gene="infB"
                     /locus_tag="VYN42_001607"
     CDS             7905..10697
                     /gene="infB"
                     /locus_tag="VYN42_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1462659.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSETAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            10948..11298
                     /gene="rbfA"
                     /locus_tag="VYN42_001608"
     CDS             10948..11298
                     /gene="rbfA"
                     /locus_tag="VYN42_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1462660.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3467 a         2014 c         2561 g         3356 t
ORIGIN      
        1 agtgacatac tatatgaata caaaaatgat gtcacaattt tctgttatgg ataatgaaat
       61 gcttgcttgc gttgaaggtg gagatattga ttggggaaga aaaattagtt gtgcagcagg
      121 ggttgcatat ggcgcaattg atgggtgtgc aacaacggtt tgacatttct attgggacca
      181 tttgctatag gaataggtgt aactggtgct gcaggtggag ctatacttgg aggtatagcc
      241 tatgcagcaa catgttggtg gtaattatgg attttaaaag ttttattatt ggtttagtag
      301 ttggtatatt tggtccttat atggatgact taattagaaa aatattttca aaatcttcca
      361 aaaaggatac ggatagtact ctctaaaaaa taaatttctc ccctgtattt gctagcttaa
      421 tttacagggg agtttcttta atattgtttc gcctgtcaaa atgatatgtg atagcaggat
      481 gaaaagtcta caaacaagtt ggtatcaata caatataaag aggaaagtat gtttttcatg
      541 cttgcttttt taatttttac aattcaagag gttttgatga ccatttatga tttgagtgat
      601 ccaaggtcaa aataagtgct atactagcag tgtaaatgtt cttgctcaac taagataaat
      661 cgcacattta ggaggaaatc ttatgaagaa aaaaatactg attattttcg ttctgtatct
      721 gatcatgtcc atctttcttt atccgcttag ggagagtatt tggtataatc tattttatac
      781 catagcctat atgattgcgg ttatgatcta tttttcttta attaaaaaga aagaaaagaa
      841 atgaaagatt ttcttgatta aaaagaatca tattctttgt gagattgttc ctgggtcagt
      901 tgcctttgct tgtttctact tatctatttc tatttcgtca gttttccaat ttcttttagt
      961 ggttattaac ttagcttcta ttttggtcac tgtttacctc actagggaaa tgcggataaa
     1021 agagtttgaa gatgatgatt tggttagtcc tagaaccaat caacttatgt tcatcggctt
     1081 gacaggcttt atgtctatta tttgtttgta tagagggatc acagcaggag aatcctacca
     1141 acaaataatc gcttatattg gcgctattct ctgcttgacc atcatgcttc tgctcatttg
     1201 gggattgaag tattataaaa agtagaggct aatgcagttt ttgcaattta agatgtcttg
     1261 atgacaattc aagatttgga tgaaaaactt tgacaaatag tgctatactg aaattgtcaa
     1321 agttgcaacg ggtgctgcta cattatgtta aaaatcgctc ttgattgata agctggattt
     1381 gttaggaaag gagtaaataa ttatggataa gaaaaagata gtttcgacta taatatgtat
     1441 agtatttctt gtagtgtcag tagataattt ttttagagac ttaaccccgt tattgttcat
     1501 tttaaatatt attggcctaa cttgtttttt agtgttaaca tacactaaca taaaagagat
     1561 actcttaaat ataagtaaat gatgatttgg ttagtcctag aaccaatcaa cttatgttta
     1621 tcggcttggt agattttatg tttgtcattt gtttgtatag aggtatttca gaaacagaat
     1681 tctatcaaca actaatcgct tatataggtg tattctctgc ttgtttatca cgcttctgct
     1741 catgtggggc ttgaagcatt ataaaaagta gctttctatc cttttctgac aagatatttg
     1801 agtagaaggc tctattaaat tgttagtgaa ataaatgaat ggaggtattt aatatgaaat
     1861 acagattatt ttttgttatt ttcttgagta gtgtgttgga tattctttta gggacatttt
     1921 tacaaatctc tatcgtatct attgggtggc ttgttcttta cagtggtttg tttgaagcag
     1981 gagttttcct tcttgctaat aaaggggtgg cggtaaaaat caaggaagta gatattcgaa
     2041 atcgctttaa atttattttt ggaaaaacct tatggtttca aattcttttg ctcatctttt
     2101 tgataatcaa actttatctt ggtttggatg cgaggttgat tttattctat ggacatattt
     2161 tcattgtctt taatgcctta atgtatctat tatctagtag tcaggttagc cttaaaaaaa
     2221 acaaactgtc ttcttaatct tacagcagta gagcctgaca aggtgaggtc atagtaggga
     2281 ggatttctat gaaaaagtat caacttctat tcaaaataag tgcagtcttc tcttacttat
     2341 ttttcgtatt tggtctttct cagctgacgc ttatcgtcca aaattattgg caattttctt
     2401 cccagattgg taatttcgtc tggattcaaa atatcttgag tttacttttt attggagtca
     2461 tgattgtggt tcttgttaag acaggccatg gttatctctt ccgcattcca agaaaaaaat
     2521 ggctttggta ttcgattttg acagtattag tggtagtgtt ccagatctct tttaacgttc
     2581 agacagctaa acatgttcag tcaactgcgg aaggttgggc tgtattgatt ggttatagtg
     2641 ggactaactt tgcagagcta ggtatttata tagccctgtt ctttctggtt ccactgatgg
     2701 aagagttaat ctatagagga ttactgcaac atgctttctt taagcattcg cgatttggtc
     2761 ttgatttgct tcttccttct attttatttg ctctccctca tttttcaagc ctgcctagtc
     2821 tgttagatat cttcgtcttt gcaacagttg gaatcatctt tgctggtttg acccgctata
     2881 ccaagagcat ttatccatcc tatgcggtgc atgtgatcaa taatattgta gcgaccttcc
     2941 cgtttttgct cacttttcta catagggtct tggggtaaaa aaacaaaagg cttgcttttc
     3001 agccatagag gaggtcatca tgtataaaca cttatttttc ctagattcca aaactttaga
     3061 tcggttgaca ccctatattc tagtcttggc ttctgacacc attgctttta atgtttttgt
     3121 gctaaccttt gtatctgcgg tggtttttaa tttcctaaat tccatgctag ctttaatggc
     3181 tatattcata ggggctggct atgtggtcgg attttggttg ctaaaatggt ttgttttgga
     3241 aaggctagat ctaaagaatg acgtgtagga agtctgtttg ttgaggagga taattttatg
     3301 gagttttttg ataaatttca tgccttgtgt tttggatttt tagtactaat aattgtcatt
     3361 atagttcctt atacgattaa ccatggggat ttttttcaaa atgaatctgc attgattctt
     3421 gtaagtcttc ttgtaacctc gctgagtgtt gcttatgcta gaaagtttga aatgatttct
     3481 tttgggatgt taagcaagaa acaacttttg cttttcattg caatctttct tctaagtgta
     3541 cttgagacgc tggtttatat tcatttcttc gctgtttctt ctggctcagg ggtccaacac
     3601 ttggcggaag tcagcagagg aatttccctg tctttgattt tgactacctc agtttttggc
     3661 cccatccagg aggaactcat tttcagagga cttcttcaag gtgcggtttt tgacaattct
     3721 tggttagggc ttgtgctaac ttcctctctc ttttctttca tgcatggacc ttctaatgtc
     3781 ccttcgttta ttttttatct acttgggggc ttgttgctgg gctttgctta taaaaagagt
     3841 caaaacctat gggtttctac tctagtccat atgctttaca acagttggcc actcttatat
     3901 tatttataaa aattatgaaa aggtaagcag aagacggtgc ttaccttttt caagctataa
     3961 tgatacccaa gccaatccag aggcttttct ttgagaatcg ggttagagtg gttgacgaat
     4021 aggccaaaaa ctagtagaat agtaaggaaa ctttatacgg aggaaagaaa tggatttggg
     4081 tgataatgag ctaacactga ctcccatacc tgggaaaagt ggcaaggctt atatgggtag
     4141 ctatcctgat gggaagcgca tctttgtaaa aatgaacacc tctccaatcc tacctggtct
     4201 agctagagaa caaattgctc cacaattatt atggagtcgt cgtttggcag atgggcgtga
     4261 tatgtgtgct caagaatggt tgacaggcaa gatattgacc ccctatgata tgaatcgtaa
     4321 gcaaatcgtc aatattttaa cccgtcttca tcgctcacgt ccgttgatga cacaattgag
     4381 tcgtttgggc tatgccatgg aaacacctgt agatttacta cagtcttggc aggaaacggc
     4441 tccagatgct ttgcgtaaaa atcattttat cagtgaagtg atggctgatt tacgtcagac
     4501 tattccagga tttagagagg accatgcgac cattgtccat ggagatgtac gacatagtaa
     4561 ttggattgag acagatagtg gcttgattta tttagtagat tgggattcgg ttcgcttgac
     4621 cgatcgcatg tttgatgtgg cccatatgct ctgccattat atttcagaac atcagtggaa
     4681 ggaatggttg acctactacg gttacaagta caatcaaacg gtattaagta aattgtattg
     4741 gtatggtcaa ttgtcttatt tgagtcagat ttccaagtat tatatgaacc aagatttaga
     4801 aaatgtcaat cgggagattc atggtttgcg tcatttccga gacaagtatg gaaagagaag
     4861 atgagagtta gaaatcgtaa aggggcaaca gaattactag aggcaaatcc ccagtatgtg
     4921 gtcctcaatc ccttggaagc caaggcaaaa tggcgggact tgtttggcaa tgataatccc
     4981 attcatgtgg aagttggaag tggaaagggt gcctttgttt caggtatggc caagcaaaac
     5041 cctgacatca actatatcgg gattgatatt caaaagtctg ttttgagcta cgctttggac
     5101 aaggtgcttg aagctggagt gtctaacatc aagctcttgt gggtagatgg ttctgacttg
     5161 actgactact ttgaagacgg tgagattgat cgcttgtatc tgaacttttc agatccatgg
     5221 ccgaaaaaac gccatgaaaa gcgtcgtttg acctacaaga cctttttgga taccttcaaa
     5281 cgtatcttgc ctgaaaatgg agaaattcat ttcaagacgg ataaccgtgg cttgtttgag
     5341 tacagtttag tgagcttttc tcaatatggc atgaaactca atggtgtctg gctagatttg
     5401 catgccagtg attttgaagg caatgtcatg acagaatacg agcaaaaatt ctcaaacaag
     5461 gggcaagtta tctaccgagt tgaggcagaa ttttaagaga taacctaaaa ttaggctgta
     5521 caagtgcttt tgctttacat aagttggcaa acgtgctata ctgatagtaa gaatatgaaa
     5581 agtgaggcgg ggaaatatct tcgcctcttg cttatgagga ggtggacgca atcgcaacaa
     5641 tcgtagaatt agtcagagaa gttgtagaac ctgtcataga agctcctttt gaactcgtgg
     5701 atatcgagta tggaaagatt ggcagtgaca tgattctcag tatttttgta gataaacccg
     5761 aaggaattac cttgaacgac acggcagact tgacagaaat gatcagtcct gtcctagaca
     5821 ccatcaagcc agatcccttc ccagaacaat atttcctaga aattaccagt ccaggtttgg
     5881 aacgtccttt gaaaaccaag gatgccgtcg ctggagcggt tggaaaatac atccatgtcg
     5941 ggctctacca agccatcgat aagcaaaagg tctttgaagg aaccttgttg gccttcgaag
     6001 aggacgagtt gactatggaa tatatggaca agacgcgtaa gaaaaccgtc caaattccat
     6061 acagtttagt atcaaaagca cgtttagcag ttaaattata gaaaaagaaa ggatagcttt
     6121 tgaggattca aaagtgaaga aaacatgagt aaagaaatgc tagaggcctt ccgcattttg
     6181 gaagaagaca agggaatcaa aaaagaagat atcatcgacg cagtagtaga gtcgcttcgt
     6241 tccgcttatc gcagacgcta tggtcagtca gacagcgtag ctattgactt caacgaaaaa
     6301 acaggtgact ttacagttta tactgtccgt gaagttgttg atgaagtatt tgatagccgt
     6361 ttggaaatca gcttgaaaga tgctcttgcc attaattcag cttatgaact tggagacaaa
     6421 atcaagtttg aagaagcacc agctgagttt ggtcgtgtag cagcccaatc tgccaaacaa
     6481 accatcatgg aaaaaatgcg caagcaaaca cgtgccatca cttacaatac ttacaaagaa
     6541 catgagcaag aaatcatgtc tggtacagta gaacgctttg acaaccgctt tatctatgtc
     6601 aaccttggta gcatcgaagc ccaattgtca aaacaagacc aaattcctgg agaagttttt
     6661 gcttctcatg atcgtatcga agtttatgtt tacaaggttg aagacaaccc tcgtggtgtg
     6721 aacgtctttg ttagccgtag ccatccagaa atgatcaaac gtttgatgga gcaagaaatt
     6781 ccagaagttt atgatggaac tgttgaaatc atgagcgtgg ctcgtgaagc aggtgaccgt
     6841 acgaaggttg ctgttcgtag tcacaatcca aacgtggatg ctatcggtac aatcgttgga
     6901 cgtggtggtg ctaatatcaa gaagattact agcaaattcc acccagctcg ttacgatgct
     6961 aaaaatgacc gcatggtacc aatcgaagaa aatatcgatg ttatcgagtg ggtagcagat
     7021 ccagctgaat ttatctacaa tgccatcgct cctgctgagg ttgaccaagt tatctttgat
     7081 gaaaacgaca gcaaacgtgc cttggtggtt gttccagata acaagctttc tcttgccatt
     7141 ggtcgtcgtg gacaaaacgt gcgcttggcg gctcacttga ctggttaccg tatcgatatc
     7201 aagtctgcta gcgaatttga agccatggaa gacgctgctt cagtagagtt ggaagtagaa
     7261 aacgatactg tagaagaata aaagctgcta gaggagggaa agatgaaaac aagaaaaatc
     7321 cctttgcgca agtctgttgt gtctaacgaa gtgattgata agcgtgattt gctccgcatt
     7381 gtcaagaaca aggaaggaca agtctttatt gatcctacgg gcaaggccaa tggccgcggc
     7441 gcttatatca aactagacaa tgcagaagcc ctagaggcga aaaagaagaa ggtctttaac
     7501 cgcagcttta gcatggaagt ggaagaaagc ttttatgacg agttgatcgc ttatgtggat
     7561 cacaaagtga aaagaagaga gttgggactt gaataagcaa aagataagta atctcttggg
     7621 gcttgctcag cgagcagggc gcatcatatc gggtgaagaa ttggtggtca aggccattca
     7681 agacggcaag gccaagttgg tctttctagc tcatgatgct ggacccaatc tggccaagaa
     7741 gattcaagat aaaagtcatt attatcaagt agaaattgta accgtgtttt caacactgga
     7801 attaagcata gcagtcggga aatcgagaaa ggttttggct gtaacagatg ctggatttac
     7861 aaagaaaatg aggtctctta tggaatagaa gaggaggaca tgatttgtct aagaaaagat
     7921 tgtacgaaat cgcaaaagaa cttggaaaag aaagtaaaga agttgtagcg cgtgcaaaag
     7981 agttaggctt ggatgtgaaa agccactcat caagtgtgga agaagctgtc gctgcaaaaa
     8041 ttgctgccag ctttaagcct gcagctgctc cgaaagtaga agcaaaacct gcagcaccaa
     8101 aagtaagtgc agaaaagaaa gccgaaaaat ctgagacagc taaaccagct gtagctaagg
     8161 aagaggcaaa accggctgag ccagttgctc cgaaaacaga aaaagtagca gtgaaaccgc
     8221 aaagtcgtaa tttcaaggct gagcgtgaag cccgtgctaa agagcaggca gaacgacgca
     8281 agcaaaataa gggcaataac cgtgaccaac aacaaaacgg aaaccgtcag aaaaacgacg
     8341 gccgtaatgg tggaaaacaa ggtcaaagca accgcgacaa tcgtcgcttt aatgaccaag
     8401 ctaagaagca gcaaggtcag caaaaacgta gaaatgagcg ccgtcagcaa gaggacaaac
     8461 gttcaaatca agcggctcca cgtattgact ttaaagcccg tgcagcagcc ctaaaagcag
     8521 agcaaaatgc agagtacgct cgttcaagtg aggaacgctt caagcagtat caggctgcta
     8581 aagaagcctt ggctcaagct aacaaacgca aggaaccaga ggaaatcttt gaagaagcgg
     8641 ctaagttagc tgaacaagca cagcaagttc aagcagtggt tgaagtcgtc cctgagaaaa
     8701 aagaacctgc agtggataca cgtcgtaaaa aacaagctcg accagacaaa aatcgtgacg
     8761 attatgatca tgaagaagat ggtcctagaa aacaacaaaa gaatcgaagt agtcaaaatc
     8821 aagtgagaaa tcaaaagaat agtaactgga ataacaacaa aaagaacaaa aaaggcaata
     8881 acaagaacaa ccgtaatcag actccaaaac ctgttacgga gcgtaaattc catgaattgc
     8941 caacagaatt tgaatataca gatggtatga ccgttgcgga aatcgcaaaa cgtatcaaac
     9001 gtgaaccagc tgaaattgtt aagaaacttt tcatgatggg tgtcatggcc acacaaaacc
     9061 aatccttgga tggggaaaca attgaactcc tcatggtgga ttacggtatc gaagccaaac
     9121 aaaaggttga agtggataat gctgacatcg aacgtttctt tgtcgaagat ggttatctca
     9181 atgaagatga attggttgag cgtccaccag ttgttactat catgggacac gttgaccacg
     9241 gtaaaacaac ccttttggat actcttcgta actcacgtgt tgcgacaggt gaagcaggtg
     9301 gtattactca gcatatcggt gcctaccaaa tcgtggaaaa tggtaagaag attaccttcc
     9361 ttgatacacc aggacacgcg gcctttacat caatgcgtgc gcgtggtgct tctgttaccg
     9421 atattacgat cttggtcgta gcggcagatg acggggttat gcctcagact atcgaagcca
     9481 ttaaccactc aaaagcggcc aacgttccaa tcatcgtagc cattaacaag attgataaac
     9541 caggtgctaa cccagaacgc gttatcggtg aattggcaga gcatggagtt atgtcaaccg
     9601 cttggggtgg agattctgaa tttgttgaaa tctcagctaa attcaaccaa aatatcgaag
     9661 aattgttgga aacagtcctt cttgtagctg aaatccaaga actcaaggca gacccaacag
     9721 tgcgtgcaat cggtacggtt atcgaagcgc gcttggataa aggaaaaggt gcggtcgcaa
     9781 cccttcttgt acaacaaggt accttgaatg ttcaagaccc aatcgttgtc ggaaatacct
     9841 tcggtcgtgt ccgtgctatg accaacgacc ttggtcgtcg tgttaaagtt gctggaccat
     9901 caacaccagt ctctatcaca ggtttgaacg aagcaccgat ggcgggtgac cactttgccg
     9961 tttacgagga tgaaaaatct gcgcgtgcag caggtgaaga gcgtgccaaa cgtgccctaa
    10021 tgaaacaacg tcaagctacc caacgtgtta gccttgaaaa cctctttgat acccttaaag
    10081 ctggggaact caaatctgtt aatgttatca tcaaggccga tgtacaaggt tctgttgaag
    10141 ccctttctgc ctcacttcaa aagattgacg tggaaggtgt caaagtgact atcgtccact
    10201 cagcggtcgg tgctatcaac gaatcagatg tgacccttgc cgaagcttca aatgccttta
    10261 tcgttggttt caacgtacgc cctacaccac aagctcgtca acaagcagaa gctgacgatg
    10321 tggaaatccg tcttcacagc attatctaca aggttatcga agagatggaa gaagctatga
    10381 aagggatgct tgatccagaa tttgaagaaa aagttattgg tgaagcggtt atccgtgaaa
    10441 ccttcaaggt gtctaaagtg ggaactatcg gtggatttat ggttatcaac ggtaaggttg
    10501 cccgtgactc taaagtccgt gttatccgtg atggtgtcgt tatctatgat ggtgaactcg
    10561 caagcttgaa acactataaa gacgacgtta aggaagttac aaacggccgt gaaggtggat
    10621 tgatgatcga cggctacaat gatattaaga tggatgatgt gattgaggcg tatgtcatgg
    10681 aagaaatcaa gagataagat tttttgctcc tttcttaggt ggtgagggac gcaagcaaac
    10741 cgatggtttc attgcttatt tttgagtcta gggtctcaaa aatcccctgt gatgggactg
    10801 ataaatcagt tccatcactt tcaccacggc gaaagaagca gatgacttca aattgaactt
    10861 cgtttcaatt taaactgaaa atcaagaagt ttaaaatagc taggtctgct ggcctagctt
    10921 ttggttcaaa gtagagaaag gaatatcatg gcaaatcatt tccgtacaga tcgtgtgggc
    10981 atggaaatca agcgtgaagt caatgagatt ttgcaaaaga aagtccgtga tccacgtgtc
    11041 caaggtgtga ccatcacaga tgttcagatg ctgggtgact tgtctgttgc caaggtttat
    11101 tacaccattt tgagtaacct tgcttcggat aaccaaaaag cccaaatcgg gcttgaaaaa
    11161 gcaactggta ccatcaaacg tgaacttggt cgcaatttga aattgtacaa aatcccagat
    11221 ttgaccttcg tcaaagacga gtccatcgag tatggaaaca agattgacga gatgctacgc
    11281 aatctggata agaactaaag aagaggggtt gcccctcttt tttggtggag gaaaataggt
    11341 tgaatttgaa atggaaaaat attcttttaa aatatattga aactagaata gtacgcct
//
LOCUS       DAVLUM010000060        11162 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLUM010000060 DAVLUM010000000
VERSION     DAVLUM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.060"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(56..286)
                     /locus_tag="VYN42_001609"
     CDS             complement(56..286)
                     /locus_tag="VYN42_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1462661.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VYN42_001610"
     CDS             complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VYN42_001610"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1462662.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(1113..2036)
                     /locus_tag="VYN42_001611"
     CDS             complement(1113..2036)
                     /locus_tag="VYN42_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1462663.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(2033..2722)
                     /locus_tag="VYN42_001612"
     CDS             complement(2033..2722)
                     /locus_tag="VYN42_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1462664.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(2787..3479)
                     /locus_tag="VYN42_001613"
     CDS             complement(2787..3479)
                     /locus_tag="VYN42_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1462665.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAMKHLG
                     ITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMPTASS
                     GGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEKLESN
                     SKYQKELEKYIK"
     gene            complement(3535..4557)
                     /locus_tag="VYN42_001614"
     CDS             complement(3535..4557)
                     /locus_tag="VYN42_001614"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1462666.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(4687..7158)
                     /gene="parC"
                     /locus_tag="VYN42_001615"
     CDS             complement(4687..7158)
                     /gene="parC"
                     /locus_tag="VYN42_001615"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1462667.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(7578..9521)
                     /gene="parE"
                     /locus_tag="VYN42_001616"
     CDS             complement(7578..9521)
                     /gene="parE"
                     /locus_tag="VYN42_001616"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1462668.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            9657..10298
                     /gene="plsY"
                     /locus_tag="VYN42_001617"
     CDS             9657..10298
                     /gene="plsY"
                     /locus_tag="VYN42_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1462669.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(10343..>11162)
                     /locus_tag="VYN42_001618"
     CDS             complement(10343..>11162)
                     /locus_tag="VYN42_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1462670.1"
                     /translation="LVLLLKSIKLARWTYYYHLKQLDKTDKDQELKAEIQSIFIEHKG
                     NYAYRRVHLELRNRAYLVNHKRVQGLIKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQ
                     GQFEGSKTMEKCYTDVTEFAIPASTQKLYLPPVLDGFNSEIIAFNLSCSPNLEQVQTM
                     LEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFG
                     ILKSEMFYGYEKSFQSFKQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3189 a         2493 c         1986 g         3494 t
ORIGIN      
        1 ctctcctaca atcaacatgg actattatat catgaaaatt tcaaaaaaac aagacttatt
       61 ttgctaaatt ataattttca atcaaaattt ccacagcttt ttccaatttt ttataaaaac
      121 tatcgacatt cccattcttt ataatggcaa attgtccgtc taattcggca atttctccga
      181 taactttttt accgatagtc aatgtataac cttcaaaact gtctttacca acattaactt
      241 tggcatccgc tacttgaatt tcgatttttt tatctttctt gctcatttca tacctctctt
      301 cactttttct attttacaag aaaatcctaa aactagcaag aaaaaactct atatcaggct
      361 tctctgatat agagttttat gtaaacaacc tcaatcgatt tagcatagct aatagttagt
      421 aaacaagcat aattgactat cctttttagg ttatcagtga gtctcaccgc ctactaactg
      481 caaatcctta tctttgtagt ctacaatagc ttcaatagct acctctatgc ctcttacaat
      541 atcacataga ctcattcctg cagtattcgg cttatttact acttgttcca tcatatatgg
      601 aatatgcatg aaacctgctc tcatattagg gaatttttta tccactaaat aaagagcttg
      661 gtacatcaaa tgattgcaaa caaaggttcc tgcactattg gatacaactg ccggaagtcc
      721 ctgttttttg atagcttgta ccatcgcttt gataggtaaa ctactaaaat aggccgatgc
      781 tccatcaata cgaatcggtg tatcaattgg ttgattgcct tcgttatcag gtatgcgagc
      841 atcatcttga ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc ctgcttgtcc
      901 aatacaaagt acagcatctg gttgatatcg taatatttct gcctctaaaa cttctgacga
      961 cttataaaaa accgttggaa tttctaccca gcgaacttca gccccattaa tctcagatgg
     1021 taataatttt acagcctcca aagctggatt aatcttttca cctccaaaag gattaaaacc
     1081 tgtaaccaat attttcattt tattttcctt tactaaaatg cgagaaagta cattaagaat
     1141 atgtgaataa caatcattac tagagcaaca cctgcttgag cctttataac gccattctga
     1201 tctttcatat ccatcaatgc tgctggtaga gcgttaaaat tagcagccat tggggtcaat
     1261 aaggtcccac aataacctgc tgtcatggca agagcaccag ccacaattgg attagctccc
     1321 agagcaaata caaagggaac tccaacacct gctgtaataa cggtgaatgc tgcaaaagca
     1381 tttcccataa tcattgtgaa tagaaccatt ccaagaacat aggccaaaac tcctataaag
     1441 cgactatctg aaggaacaat accgctgatc agatgagaga taacatcacc aacacctgct
     1501 acagtaaaaa tagcccccaa agcccctaat aattgaggaa caatcccact tgttgaaact
     1561 tgctgagtca ttcgattatt ttctgataac agactcttag ggtgactatt ggtaatcaca
     1621 agaacagaaa ttgtagcaaa caaggcggca aggctaatcg aaatcttgct aaattctgga
     1681 atcatttgcg ctaagaccaa cgcaagtatt gccatcagca taactggaat aaaaatttta
     1741 tttttcaacc tgttagattc aatattggct ttcatttcat ctaaggatgg caaggttccg
     1801 atacggactt gcttaaacaa tgttaacagc gataatagga ttacaataat accaatactc
     1861 atatttggca tataggaacc acctataaac gtaatagaca atagagtcca aaatgcagat
     1921 gtcccaagtc gaactgggtt tgttttatct ttataactac aataggctgt atggagaaat
     1981 tgacaaccaa tcacaatata ggtcaactct aatagttgct ttgccaactc tgtcattttt
     2041 gttctcctcc cctagtcttt tttgatatca attttttatc aaataaataa ttgtaaatcc
     2101 ccactacaat aagtgttata acagcaacaa taatagatgt agaagcaatc cctgcataat
     2161 tgctttcata gcctaactga tctaatgttc cccctatcaa gaggactccc ccagcaccta
     2221 caaacgtatt ttgagcaaag aaatttccaa aattttcatt cgctgccgca cgcgctttta
     2281 ttgtctcatc ttcaacctct gttaactttc tacctaattg agactctgca gctgcttctc
     2341 ccataggttg aaccaaaggt ctgacaaact gagggtgtcc tcctagacga attgaaaaga
     2401 aaccagctaa ctctcgaata aagaaataaa ctgtatagaa gtttccaact gtcagacctt
     2461 taatctttcg aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct gacagcccca
     2521 caagaggcaa ggtaaccata aaaatcgtga gcactcgctg attgctaaat tcttttccca
     2581 aaatctccaa aaattcaacg agagaaacac ctgaaactaa agctgtaacc aaaccagcta
     2641 agactactgt tgcaattgta tcaaatttta aaataaaacc cacaacaatg attgctattc
     2701 ctattaatct aatccactcc atatcaaact cctttatatt caaaatgaca gtattttaaa
     2761 aattttatca agatcaatac cattccttat ttaatgtatt tttctagttc tttttggtat
     2821 ttgctattgg attccaattt ttctttttgc cattttttaa aaacctcgtt atattctttt
     2881 gttgtaacaa tatctttttg caatttcatt cctttaaaga tatatggttc ccccttaata
     2941 ccaacttgtg agtatggttt tgagaatggt actacgttac ttacaactgg agaaccacca
     3001 gatgaagctg ttggcatcaa taatgaacta tctgtcgacc aagcttgagc tttggcatat
     3061 ttttcatatc tcttctctag gtcagtggtc tcagaaacag catcttctaa caatttctta
     3121 tatttatcca aaccaggttt agctacaaca tccttatctt ttcctttcgt aatgccaagg
     3181 tgtttcatgg cagaaccaga ttttggatcc ataatattca agtaagacgc tggatcttga
     3241 tagcttggag cccatcctgt actgttcaaa tcatagtctt tttgagaagg agcaacattg
     3301 ccgtatttat cattttccat caaaccatca ataacgtctg tcctcgatgt tcgagtcgct
     3361 atactgtagc ccaatgatgc tggatctact gcatagacat aagaaaatgt tgtcggtgca
     3421 tctgcttctt tatcagtttt tccacaagcc actaaaatag ctgacgtgct caggaccact
     3481 cctgctgtta agagccactt tttctatttc ataaaaaatc tcctttggtt tattttaatc
     3541 tacttttaca atccaacctt ctggcgcttc aatatcgcca aactgaatac ccgtcaattc
     3601 attatataat ttacgcgtca caggacctac ttctgtttca ctatagaata catggaaatc
     3661 atcaccatgt tgaatacctc caattggaga aataaccgct gctgtaccac aggcacctgc
     3721 ctctacaaaa cggtcaagat tatcaattgg aacatcaccc tcaataggag ttaatcccaa
     3781 gcgatgttct gccaaataaa gcaaggaata cttggtaata gatggcaaga tagatggact
     3841 caatggtgtt acaaattcat tatcagctgt aattccaaag aaattagctg atccgacttc
     3901 ttcaatcttt gtatgagttg atgggtccag atagataaca tctgagaaat ggcgtgactt
     3961 ggccattttt cctggtaaga gacttgcagc atagtttcca ccaaccttag ccgcacctgt
     4021 accatttggt gctgcacggt cgtactcatc ctgaatcaag aagttggttg ggaccaaacc
     4081 acctttaaag taatttccaa ctggcatagc aaagatggtg aaaatgtact cttctgccgg
     4141 ttttaccccg ataatatctc cgacaccaat caaaagaggg cgaagatata aggttccacc
     4201 tattccgtat ggtggtacgt attcttcatt cgcacggaca actgctttac aagcttctac
     4261 aaacatgtct gtcggaactt gtggcatcaa gagacggtca catgtacgtt gcaggcgttt
     4321 agcattttca tcaggacgga acagttgaac actgccatcc ttagtacgat aagctttcaa
     4381 accttcaaat gcttgttgtc catagtgaag acttggagaa gactctgaaa tatgcaaagt
     4441 tgcatcctct gtaagctctc cttgatccca ttgtccattt ttgaaatgag caagatagcg
     4501 ataaggtaat ttcatatagg aaaaaccgag gttttcccaa tcaatcgtta ctgtcatatt
     4561 ccactcctta ttctaaaaac ctatttctta tattctacac tatttttcta aaatagcaag
     4621 tatattttgt aattttcaga aaattcctcc aataaaaacc atcttagaac tgattcttca
     4681 tttcacttat ttatcttcag taactacttc ctgaagataa gcgtcaaaaa cttcttcatc
     4741 tgaaatcgtg tcagaaatga agcttccatt gctagtgcgt tctgacaagt tcaagtcttg
     4801 caatcggctt tcatagattg ttcctttatt ggattggaca agcagagttt ggtcgttcac
     4861 atccacttcc gtactgaaga aatcgccaac aaatccttgc tctgcaactg ctcctgccaa
     4921 gaagacacga tgcggtttgt ttttcaactc acgcaagact tgtaatcctc gtttggcacg
     4981 gctggttgct agaatttcct caatggaaac acgtttcaag cttccacgct gggtcaagag
     5041 gtagaaggac gaagtattac agataaagcc agattggagg acatcatctt ctttcaaatt
     5101 catagccttg acacctgctg ccttagcacc gacaaccgga acctcttcga tattgaaacg
     5161 cagggcataa ccattttgac taaccaagac aacatcatct agtttaatcg gagccactgc
     5221 tacaatctga tctgtatcgt ctttgagctt agcatacttg acagacttag atctataggt
     5281 ccgccatgga gtgaattctt ttcgctctac ccgtttgatt tgaccaaggc gagtcgctgc
     5341 aaagtaggtt gtcgcatcgt caaactgatc cagtacttcc acataaagga tttcttcatt
     5401 cgtttcaaag tttgtgatgg tttggctcag atgctctccg atgtccttcc aacgaatatc
     5461 tgccaactca tggattggtc tgtagatgac atttccaaga cttgtgaaca tcaagaggtg
     5521 ctgggttgtc ttggcagatt gaacaaaaat caaacggtca tcatcacgct tgccaatttc
     5581 ttccaaggtg gaagccgcaa aggaacgtgg actggtacgc ttgatgtaac ctgccttggt
     5641 cacgctgacg taggtatctt cctcagcgat aagactagct gtatcaatct caattgcttt
     5701 cgcagtgtct tctaaagaac tcaaacgagg agttgcaaat ttcttcttga cctcacgaag
     5761 ttctttcttc atgagattgt acatagtcct ttcatcacca ataatagccg ccagcatagc
     5821 aatcttctca cgaagctctg cttcttcttc ctgcaagaca accacatcgg tattggtcaa
     5881 acggtacagt tgcaaagtta cgatagcctc agcctgttct tccgtaaaat catagctaac
     5941 tttgaggttt tccttggcgt ccgccttatt ctcagaagca cggataagag caatgacttc
     6001 atccaaaatc gaaatcacac gaatcaaacc ttcgacgata tggagacgtt tctcagcctt
     6061 ttctttgtca aagcgtgaac gcgccaaaat cacttctcga cggtgagcga tgtagctaga
     6121 caggattgga acaatcccaa cctgacgagg tgtgaaattg tcaatcgcca ccatattaaa
     6181 gttgtagttg atttgtaggt cggtgtactt aaataagtag ttgagaacaa gctcagtatt
     6241 agcgtctttc ttaagttcga tagcgatacg aagaccatca cggtcagact catcacgaac
     6301 ctcagcaatc ccagctacct tgttattaac acgaacatca tcgattttct tgactagatt
     6361 ggccttattg atttcataag gaatctcagt aataacgatt tgttccttac caccttttag
     6421 cttttcaatt tcagtcttgg aacgaacaac cacgcgccct ttcccagtct cataagcttt
     6481 cttgatttca tcacgaccct gaataatagc ccctgtaggg aagtctggtc caggcaagaa
     6541 ttccatgagt ttatcaatct ttgcagttgg gtggtcaatc atgtaaactg cagcatctat
     6601 gacctcagct aaattatggg gaggaatgtc tgtggcataa ccagccgaaa tcccagtcga
     6661 accattgacc aagaggtttg gaaaggctgc tggcaagacc gttggttctt tctccgtatc
     6721 gtcaaagttc catgcaaaag gaactgtctt tttctcgata tcctgaagaa ggtagcctgc
     6781 aatttcagac aaacgtgcct cagtataacg catagccgca ggaggatctc catccataga
     6841 accgttatta ccgtgcattt caactagaat ctcacgattt ttccagttct gtgacatacg
     6901 aaccatggca tcatagatag aagaatcccc gtgtgggtgg aaattcccca tgatgttccc
     6961 gactgacttg gccgacttac ggtagctctt gtcaaaagta ttgctatcct tattcataga
     7021 ataaagaata cggcgctgaa ccggcttcaa cccatcacga atatctggca aagcccggtc
     7081 ttgaataatg tacttggagt agcgaccaaa gcgctctccc atgatgtcct ccagggacat
     7141 gttttgaatg ttagacataa gatacaaagc ccataaaata ccaagtgaaa atagaaaatt
     7201 cttgaagtaa gcaaactcac aagagaattt atctttttca cacaatatct agggcgtgtt
     7261 caactccttt caaagaatgt agagtaggtt tttatgcagt aaaagatatt ttacgggaat
     7321 tcgtcccgtg ttcagttacg ataagtaacc aaactatcct gtttgtattt ttcaatatga
     7381 aaatctggtt ttccaaaatt agtcttagtt tgtgtcttaa ccgctccctt aagcgcctct
     7441 ttaagataag cactcatagc agattcttca ttaataatcc tgcaattttt tcaaaccaag
     7501 attttcaatc tgctttttca catagtcatt cacatccgac tctaatttcc agtttactaa
     7561 catattattt tctttcatta aaacactgtc gcttcttcta gcgtaaactt gacattatct
     7621 tcaatccatt tacggcgtgg ttctacctta tctcccatga gaacattgac gcggcgttcg
     7681 gcgcgcgcta aatcttcaat tgtgacacgg atgagggtac gtgtttctgg gttcatggtt
     7741 gtttcccaga gctggtccgc attcatctca ccaagtcctt tgtatcgttg gagggtagcg
     7801 cctttaccga actgtttacg gagttcttct agttctccgt ccgtccaagc gtaggccact
     7861 tcttctttct tgcctttacc tttggacatc ttgtaaagag gtgggagggc aatatagaca
     7921 tgacctgcct cgactagcgg acgcatgtaa cggtagaaaa atgtcaagag caaggtctgg
     7981 atatgggcac cgtcggtatc cgcatcggtc atgataatga tcttatcata gttggcatct
     8041 tcaatagaga agtctgctcc aacacccgca ccaatggtat aaatcatggt attgatctct
     8101 tcatttttga ggatatccgc catcttggcc ttggctgtat tgataacctt accacgaaga
     8161 ggtagaatag cctggaactt gcggtcacga ccttgtttgg cagaaccacc ggcagagtcc
     8221 ccctcaacta gatagagttc attcttagca ggattcttag attgggctgg ggtcaatttc
     8281 ccagacaaca agcccttatc tttcttgttt ttcttcccat ttcggctctc atcacgcgcc
     8341 ttacgtgctg cttcacgagc atcacgggcc ttgatagcct tgcggatgag gttagaagct
     8401 aattccccat tttccataag gaaaaaggtc aacttatcag ccactattcc atccacaact
     8461 gggcgagcta gggggcttcc tagtttatcc ttggtctgtc cttcaaactg caagtgttct
     8521 tcaggaacta agatagaaag aacggccgct agtccctcac gatagtctga accttcaagg
     8581 tttttatctt tttccttgag aagacctgtt ttacgtgcat agtcattcat gaccttggta
     8641 atggcagact tgagtcctgt ctcgtgcgtt ccaccgtcct tggtgcgaac gttattgaca
     8701 aaggatagaa tgttatctga gaatccgtca ttgtactgga gggctacttc cacttgaaaa
     8761 ccattgtctt ccccttcaaa gtaaagaact ggcgtcaaga tttccttatc ttcgttgaga
     8821 taagaaacaa aatcttgtac tccattctca tagtggaact caatcgcttc atctgttcgc
     8881 ttgtccgtta aagacaaggt cacatttttc aagagaaagg ctgattcatt aaggcgctct
     8941 gaaatggtat tgtacttgaa atctgtcgta gaaaagatag tcgcgtcagg cataaaagta
     9001 actttggtgc ctgttttaga cttgggtgct gtaccgattt tcttcaaagt cgtgacaggt
     9061 tttccaccat tttcgaaacg ttgcttgtaa actgcgccat cacgggtaat ttcaacttct
     9121 aaccagctag aaagggcgtt aacaacggaa gaacccactc cgtgaagtcc acctgatgtc
     9181 ttatagccac cttgaccgaa tttccctccg gcatgaagaa tggtaaagat aacctcaaca
     9241 gttggaattc ccatagcgtg catacctgtc ggcatcccac gtccatggtc ttgaaccgtt
     9301 agactaccgt ctttattgat agttacatcg atacgatcac caaacccaga caaggcttca
     9361 tcgactgcat tatcaacgat ttcccaaact aggtgatgaa gaccagcgcc atcggtcgat
     9421 ccaatataca tccccggacg ttttcggacc gcatccaacc cttctagcac ctgaatagca
     9481 tcatcattat aattgttaat attgatttcc ttttttgaca caaggaacct cctattcgtt
     9541 catctttact attctacagg ttttccaagg attttgcaaa atttttcttt ctccgatgtg
     9601 acaatttcag cagagattct ctgcttttct ttcccaattc atgatataat aggagtatga
     9661 ttacaatagt tttattaatc ctagcctatc tgctgggttc gattccatct ggtctctgga
     9721 ttggacaagt attctttcaa atcaatctac gcgagcatgg ttctggtaac actggaacga
     9781 ccaatacctt ccgcatttta ggtaagaaag ctggtatggc aacctttgtg attgactttt
     9841 tcaaaggaac cctagcaacg ctgcttccga ttatttttca tctacaaggc gtttctcctc
     9901 tcatctttgg acttttggct gttatcggcc ataccttccc tatctttgca ggatttaaag
     9961 gtggtaaggc tgtcgcaacc agtgctggag taattttcgg atttgcgcct atcttctgtc
    10021 tctaccttgc gattatcttc tttggagctc tctatcttgg cagtatgatt tcactgtcta
    10081 gtgtcacagc atcgatcgcg gctgttatcg gggttctgct ctttccactt tttggtttta
    10141 tcctgagtaa ctatgactct ctcttcatcg ctattatctt agcacttgct agtttgatta
    10201 tcattcgtca taaggacaat atagctcgta tcaaaaataa aactgaaaat ttggtccctt
    10261 ggggattgaa cctaacccat caagatccta aaaaataaaa tgccagttct gtgaactgca
    10321 ccccaaaagt tagacaatta atttatccga aggatttagt tctgtattgc acagggctaa
    10381 gtccttttag ttttacctta attcgtttat tgttgtagta atcaatatag tctataatag
    10441 cttgttccaa ttgcttaaac gactgaaacg acttctcata accgtaaaac atttccgatt
    10501 tcagaatccc aaagaaggac tccatcatac cattgtctgg gctgttaccc ttacgtgaca
    10561 tggatgcttg aattccctta ctctctagga accgatgata agaatcgtgt tgatattgcc
    10621 agccttggtc actatggaga atcgtattct cgtagtgctt ctctttgaat gcctgttcca
    10681 acattgtttg tacttgttct aaattaggcg aacaagaaag attaaaagca ataatttcac
    10741 tgttaaagcc atctaaaact ggtggtaagt aaagcttttg agtacttgct ggaatggcaa
    10801 attctgtcac atctgtgtag cacttttcca ttgttttaga gccttcaaat tggccttgaa
    10861 tgagattctc tgccttcttg ccaacgtctc ctttatgaga agaatatttt cgtttctgtc
    10921 gcattttagc ttgtaaattg agtactttta tcaagccttg aactctttta tgatttacca
    10981 gataagcacg atttcttagt tctaaatgaa cccggcgata agcataattt cctttgtgtt
    11041 cgataaagat ggattgaatt tcagctttaa gctcttggtc cttatctgtt ttgtctagct
    11101 gtttcaagtg atagtagtag gtccaacgag ctagtttaat ggattttaga agaagaacta
    11161 ac
//
LOCUS       DAVLUM010000061        11051 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLUM010000061 DAVLUM010000000
VERSION     DAVLUM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11051
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.061"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(41..205)
                     /locus_tag="VYN42_001619"
     CDS             complement(41..205)
                     /locus_tag="VYN42_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462671.1"
                     /translation="MDESKYLCYLEKYDALGSGRLLAKVNNTYYMFNKNQIELLRYSN
                     KNAKKERKYM"
     gene            complement(591..1451)
                     /locus_tag="VYN42_001620"
     CDS             complement(591..1451)
                     /locus_tag="VYN42_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1462672.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(1726..2712)
                     /locus_tag="VYN42_001621"
     CDS             complement(1726..2712)
                     /locus_tag="VYN42_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1462673.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(2984..4459)
                     /locus_tag="VYN42_001622"
     CDS             complement(2984..4459)
                     /locus_tag="VYN42_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1462674.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(4717..5640)
                     /locus_tag="VYN42_001623"
     CDS             complement(4717..5640)
                     /locus_tag="VYN42_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1462675.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(5654..6583)
                     /locus_tag="VYN42_001624"
     CDS             complement(5654..6583)
                     /locus_tag="VYN42_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1462676.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(6902..7123)
                     /locus_tag="VYN42_001625"
     CDS             complement(6902..7123)
                     /locus_tag="VYN42_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462677.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(7077..7337)
                     /locus_tag="VYN42_001626"
     CDS             complement(7077..7337)
                     /locus_tag="VYN42_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462678.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            7417..7554
                     /locus_tag="VYN42_001627"
                     /pseudo
     CDS             7417..7554
                     /locus_tag="VYN42_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(7658..7813)
                     /locus_tag="VYN42_001628"
                     /pseudo
     CDS             complement(7658..7813)
                     /locus_tag="VYN42_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(7999..8610)
                     /gene="rpsD"
                     /locus_tag="VYN42_001629"
     CDS             complement(7999..8610)
                     /gene="rpsD"
                     /locus_tag="VYN42_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1462679.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(8805..9857)
                     /locus_tag="VYN42_001630"
     CDS             complement(8805..9857)
                     /locus_tag="VYN42_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1462680.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(9854..10552)
                     /locus_tag="VYN42_001631"
     CDS             complement(9854..10552)
                     /locus_tag="VYN42_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462681.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(10719..>11051)
                     /locus_tag="VYN42_001632"
     CDS             complement(10719..>11051)
                     /locus_tag="VYN42_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1462682.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         3237 a         2277 c         2094 g         3443 t
ORIGIN      
        1 ataaattggt ctatggtatt actagtatag caggaaaact ttacatatat ttcctctctt
       61 ttttagcatt tttatttgag tatcgtaaga gttcaatctg atttttgtta aacatatagt
      121 aagtattatt aactttagct aataatcgtc ctgagcctaa agcatcatat ttttcaagat
      181 agcacaaata ttttgattca tccatcctaa attatctcca catcaaattc tgtgcattct
      241 cgtttgacat cagcggactc ctcctataaa attacgatta gattgcatat atctagtgat
      301 tgtcgagtta atgaaattat tgtatactat attcaaaata ttgtcaacaa aaaaatagaa
      361 aattttctga taatttgtga ttaaaaccaa taccatacct ctcccatcat tgaaaagcgc
      421 agtcattact taaaaagtca ctcgtttatg ttataatagg ctccataata tccatagggg
      481 atttacccac tacaaatatt atagagccga ttttcattga gtagcaatcc tgtcatcctt
      541 ggcaggattt ttctatttca aaaaagcaag tcgattgacc tgcttctgct ttacttttct
      601 tgtgctaatg ttttaaaatc tttgtctaat atgggttgca cttctatttg attggcgtct
      661 agttggtggt aaaaagatgg gggtaatacc tctaagaatt ttgcatagtc caagcgagct
      721 atggattcat agtcttctgg tttagagccg tctcctgtga tttgaaccaa gtcaatctcc
      781 cactggactt ccttatccac caattgctca atataggctg caggaacaaa cggttctctc
      841 ggtaaaactg tcttgactcc ttgagctaga tggtaaacgc catgcacttt tccttctcca
      901 tcctgataga aggaaactct cgcaaagtag gcatctgtct cttgaaccgc acgcacacgc
      961 gcttcaaact gagccaagcc atctgcctct aaaaagcttt tcaagttctc acgactaaag
     1021 aaaataggat taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc tgctagatag
     1081 gcttgaatac ttgcttggaa ataagcttca aaatcaaaac catctagccc ttcaatatca
     1141 gtccctgtat aagcaagcaa agcatctaaa aatgacttga taatctgcca gtctgtcttt
     1201 gttagtaggt caggaagatc gacacggtaa gccttttgac catcagcata actgacctta
     1261 aagagaaatt gtgattgccc cactatcgca cactcaatat actcgagacg attaagaggc
     1321 tgacggagat agactacatc atagctatgt gactccaaac cgtctagcaa ggccaagatc
     1381 gacttggcat tcaaaatctc ttgttctcct aaaatgctct gtttatttgg aataaaaaat
     1441 gttttcgcca taactggact cctttgaaat cgtttacata cagtatacct tatttttctg
     1501 aaagatacaa aaacaaactt tatattcttc gaaaatctct tcaaaccgcg tcagcttcgc
     1561 cttgccgtag atatatgtaa ctgacttcgt cagtcttatc tacaacctca aagcagtgct
     1621 ttgagcagcc tgcggctagc ttcctagttt gctctttgat tttcattgag tattagattt
     1681 ttgagtacaa agcatagaaa aacagcccct aaggactgtt tgatcttata cagtagctgc
     1741 ctgatccaag ctttcaccga tagcggctag gcgctcaatc acttcagctt gtgtcaattc
     1801 attttttgaa acatagcggt tacgtgggtg aacacggcac tcgtgtgagc atccacgaag
     1861 gtacttgtct tcattttctt ctgatgtcaa gatacgacgg ttacagaagg gatttccaca
     1921 gttgacataa cgttcacatg gtgttccatc aaaccagtct ttccctacga tggttgggtt
     1981 gacatggttg acatcaacgg caatacgctc gtcaaagacg tacattttcc catcccaaag
     2041 ctcaccttga acttctgggt ctttaccgta agttgcgatt cctccgtgca attggccaac
     2101 atctttgtaa ccttcacgaa ccatccagcc tgagaatttc tcacagcgaa caccacctgt
     2161 acagtaaacc acgacacgct tgtccatgaa tttttctttg ttgtcacgga cccattgtgg
     2221 taactcacgg aagttgcgaa tatctgggcg aatagcccca cggaaatgtc ctaggtcgta
     2281 ctcataatcg ttacgtgtgt caaggacaac ggtatcttta tcaagaagcg cttctttgaa
     2341 ctcttttgga gacaagtaag cacctgttgt ttcaagtggg ttgatgtcat tgtcaaagtc
     2401 gttgtcttcc aaaccaaggt ggacaatttc tttcttgtag cgaacaaaca tcttcttgaa
     2461 ggcttgttca ctttcttcgt caatcttgaa ccagagatct tccattcctg gaaggctgtg
     2521 aacgtagtcc atgtattttt gagttgtttc atagtcacct gaaactgttc cgttaattcc
     2581 ctcgtcagcg actaggatac ggcctttaag gccgattgat ttacagaaag ccaagtggtc
     2641 tgcagcaaat tgctctgcat tttcaattgg agtataaagg tagtaaagta agacacgaat
     2701 atcttttgcc ataagatttg ttctcttttc tattcttaaa ttttctaaat tttttattta
     2761 tccatactag tatacctgct tgagaaaacg aatgcaattt atttgactgg aaattgtaga
     2821 ggattctcga aatttcctga atggttaaaa taaggacaag agaaaacagg gatatctata
     2881 tccttgtgcc aaaaaaacca ctgccctccc cagaccaacc tgaggaaagc agtgattctt
     2941 attttaggag ttaggaatga atacacgaaa tcaatttagc tgattatttt ttgtttttca
     3001 agaattcatc gtattgtttt tgcatttcgt tcaatacttt ttcgtaggca ccttcagatt
     3061 tcaatttttc catcaattct ggaatagctt tatctgggtc tacagtacca gtgttgatag
     3121 ctgtatcaaa ttgttgcatt gtgttagcaa tagctgagat ttcagatttc acattgtcag
     3181 tattgaagat aaatccaagc gctggagatt ctttagcttc tgccaattct ttcttagaat
     3241 tttcgatttg ttggtctgta acgttttcgt tgatgtaaag gatccagttg ttaccagtgt
     3301 tccatccacc catgtgagtg tttcctttgt agccatcaag aacgcgaaca cggttttctt
     3361 taccttcaat tttttcccag ttcttgcctt ctggaccgta aacaagaccg ttcaagagtt
     3421 ctggattcgt attcaagagg ttcaagattt ccattgattt ttctttgttc ttagagttgt
     3481 ttgagatgac aaagttagca acttgtgttg tttggttttt cttgatgaag ttagtaattg
     3541 gtttgatttg gatatctttg ttggcaacac gtgaaagcaa gctgttaccg tagtcagctg
     3601 gtcctactgt ttcttcacga acgaaccaag tatcttgttg aaggtcaaag gaagtatcgc
     3661 ttgttgcgac gtcttttgga atgtagccag cttcatagaa tttgtgaaga gtcttcaagt
     3721 gttctttgaa acgaggcact tcgtaacggt ttacaacttt agtagtatcg ccttcaaggt
     3781 cgataacgaa tggaagaccg tttgctactg ggtagtcaaa gttatcagat gggatgaaaa
     3841 ctttaccaat agcaaatggt actacgtctg gagctttttc tttaatttgt ttcaagactg
     3901 gctcaagagt ttcgtaagaa gtaacacctg aaatatcgat accatattta gcaaggagag
     3961 ttccgttgaa ggcaaagttt tgagatgatg caacgttggc tgcaactgga acagcgtaaa
     4021 tcttaccatt tacagtatta cccttgatgt aagctgggtc aagtgccttg taaaggtctt
     4081 taccttcttt tttgtacaat tctgtcaagt cagcgtaagc acctttttga gcatttacaa
     4141 tatagttatc tgcaaaggca atatcatagt tttcaccaga tgatgtgata actgacattt
     4201 tcttaccata gtcaccccag ccaaggtatt ggatatccaa tttggcacca actttttctt
     4261 caatgatttt gttggcattt gctaacaatt catccaagtt gtctggtttg tcaccgattt
     4321 ggtacatttt gataacaggt ttgtcacctg aatcagcagc ttttttgctg ttacctgtca
     4381 aatttccaca agcagcaaga cctgcagcca aagcgactac actagcagat gcaaaagcat
     4441 attttttcca gtttttcatg ataaaaactc ctttttttat ttttaaactt ataaacaatg
     4501 taatgatctt atactcaatg aaaatcaaag agcaaactag aaaactagcc gcaggctgct
     4561 caaagcactg ctttgaggtt gtagataaga ctgacgaagt cagttacata tatctacggc
     4621 aaggcgacgt tgacgcggtt tgaatttgat tttcgaagag tattaacttc acacaaggga
     4681 agttgggaac tgagaaatgt tctttttcaa taagcactat tctttcacac caccgatagt
     4741 caaacctttt acaaagtagc gttggaagaa tggatataaa atcgcgattg gaagggttgc
     4801 aaccacaacc atggccatac gacctgtttc tttcggtaga gcaactccca gttgaccagt
     4861 caagccgacc gctttggcaa tgtagtccat attttgttgg atttgcatga gcaaatattg
     4921 caatggatac aagttatcac tcttgatgta aagaagggcg ttgaaccagt cattccagaa
     4981 accaagagct gtcaaaagcg tgatggttgc gatacctggt agtgacaatg gcaaacagat
     5041 ttggaagaaa atccgggcct cactggcacc atcgatacga gccgattcga gaatggcttc
     5101 tggaatggtc ttcttgaaga aggaacgcat caagatgata ttgaatggtg agagaagcat
     5161 tggaacaatc aaggcccaaa cagtgtcacc aagctgaagt acacgggtca ccatgatata
     5221 acctggtacc aaaccagcgt tgaacaacat actgagaagg acgaagatgg taaaaaatct
     5281 gcgatactta aaggttgtcc gtgaaatagc gtaggcatag gttgttgtga taaagacatt
     5341 tgtcaatgtc ccaactacgg ttacaaagac agagatgaag agggcttgta ggattttatc
     5401 cttaaactgt gccaaaaact caaaaccgtc taagccaaat tgggatggga agaagctata
     5461 gccgtattgg aggaggcttt tctcgtctgt cactgaaata atgataacga atacaaaagg
     5521 taggatacaa gagagggcaa tcaaacccga aatgatactg aagaagatat ctgctttctt
     5581 actgaaggag tgaatgccga cattatcaat tttttctttt ttaattttct tttttgccat
     5641 attctcctcc tttctagaac aaagctgagt ttggatcgac tcgtcttgca agcaagtttg
     5701 ataggataac cagaatcaaa ccaacaacgg attggtaaag accggctgct gcagccatac
     5761 cgatatctgc tgtctgagtc aaaccattaa aaacatatac gtccaaaacg ttggttacat
     5821 tgtaaagctg accagcattg tgtgggattt gatagaagag accgaagtct gcgcggaaga
     5881 tatttccgac tgcaaggatg gtcaatacag ttacaagcgg agtcaactga ggaatggtta
     5941 cgttgcgaat acgttgccac ttgctagctc cgtccactgt cgctgcttcg tagtaggttg
     6001 gatcaattcc catgatcgtc gcatagtaca tgacactgct atatccaaaa cctttccaaa
     6061 tacctaggaa aagtaggaga tagggccaga tgcccaggtc agcgtagaaa ttgacttctt
     6121 tgagaccaag actttccaat agatgattga acaccccttt atcaatattt aggaaggcat
     6181 ctgtaaagaa actgatgata acccaagaca agaagtaagg gaacaacata gaagtttgga
     6241 aaatcttcac cattctctta gaacggagct cgctgaggat aatggcaatc cctacagata
     6301 caactaaacc tagaaagata aagccaagat tgtagaggac agtatttcgt gtgataataa
     6361 aggcgtctct tgaactaaat aagaatctga aattatcgag tccgacccat ttactattta
     6421 tgatactatc tatgaaacca ttactggtca tgtggtagtc tttgaaggca accacgttcc
     6481 caaatactgg aatgtaaaag aatagaatca accagagtgc ccctggcaaa accatcaaga
     6541 gaaagatcca gttgtctctc aatgtttttg aaaacttttt cataatttcc tcccttttta
     6601 ttttgatatc catctaaaaa ttctttttta gacttttgat aacgattaca ttattagtat
     6661 actcctattt gcaggttaga ttaaactcct aattatagaa aaaactccac aaattatgta
     6721 gcagatttaa aactttatca ccactatcaa acaaatgtcc taaatcaatt gtttatttta
     6781 tctctattag cccagtgatg gcgtcactct gttataagca tccaacaacg gggtatactg
     6841 aaaaatctcc agactaggga actcagagat agttcctaat ctggagattt ttaatatgtt
     6901 attaggcgtt tgctttcaac ttagcaataa cctctttaag attatcaatc acctctgctt
     6961 cagtatgctc agagcctttt tcatctgcca agaacaaaac tgctttttga agttcttttt
     7021 gagagttttc aaggacatcc ttatctactg tttcaaggtt tgagtcttta agaagtttac
     7081 ttaattcctt ggctaatttc ttgagtttga tttgcagact catcttctcc tgctgtttct
     7141 ttgcccgctg tttgtcctcc atccttagtt gctgactggc tttccttaat ggactctagg
     7201 gaagcaatgg catctttgac tgtttgcaag atatcacgta aaccttgctc tgtcaaacta
     7261 tcatctgcaa aagctttctt agcctctgcc aaaaccagac gtgctgaatc tgtggtagga
     7321 ttcgatacac ctgtcaatga tctcaaaaga ttttctaagg tttgagtctg cttactaata
     7381 ctagactaaa atcaaaaagt attatataac agtgatatga aatcaactaa agaagaaatc
     7441 caaaccatca aaacactttt aaaagactct cgtacagcta aatatcataa acgccttcaa
     7501 atcgttctat tttgtctgat gggcaaatct tataaagaga ttatagaact tttatagtag
     7561 tttgaaataa gatgtgaaca tctctatcag gaaagtcaaa ttaatttata gaaatatttt
     7621 agcagccaag gtgtactgtt atagattcaa tacactatac ttggtggttt agctctcctg
     7681 ttttctcttt tagctttaac cagccataaa tggtattacg tgagatttgg aaaacgtgtg
     7741 atgcttctgt tatactacct gttcgctcac aataagagag aactttttta cgaaaatcta
     7801 ttgaatatgc cataaaagga ttataccaca ttgtgtacta tttttggttc attttactat
     7861 atcactttgg actatatcgg tctagttatg tctcaacgat tatagctgga tactaagaga
     7921 aatcaaaaaa gcactaaggg agaacgtccc aaagtgctta atatcaaggc ctcaaagcct
     7981 atcttattca ataaaatatt acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt
     8041 gatttctggg ttgatttcgt cgcgttctgg caagcgagtc aatgaacctt ccaacttttc
     8101 agcgtcgaat gatacgaatg ctggacgtcc aagagtagct tctactgctt caaggattgc
     8161 tggaactttc aatgattttt cacgaactga gatcacttga cctggagtta cgcggtatga
     8221 tgggatatca acgcgtttcc cgtcaacaag gatgtgaccg tggtttacga attgacgagc
     8281 ttgacgacga gtagtcgcga gaccaagacg gtaaacaacg ttatccaaac gacgttccaa
     8341 aagaagcata aagttgaaac ctaggattcc gcctttgatt tttgtagctt gtacgaacaa
     8401 gttacggaat tgtttttcac ctacaccgta agtgaaacga agtttttgtt tttcagccaa
     8461 ttgcaaaccg tattctgaca atttagaacg gttgtttggt ccgtgttgtc ctggtacgta
     8521 gttacgacgt gccaattctt tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg
     8581 tttccaagat ggtcctgtat aacgtgacat atgaatgtcc tcctgatata aataatattt
     8641 cggtggaaat agtcacttag aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc
     8701 aaggttactt gtcataagac acctgttgac gagcttcatg ctttcctgct gatatttcac
     8761 acaaaatcta ttctaccatg aatagctgga tttgtaaagg ggttttaggc tttattttca
     8821 ctaccagaga ggttgagaac gagggtaaag gtacttccta gaccgtactg gctgctgact
     8881 gtgatttccc cacccaattg atgggccaat tcacgcgcaa tcgcaagtcc taatccatga
     8941 ccacctgtct tcatgttacg cgaagtttcg acacgataaa gacgtttgaa aatattttcc
     9001 aaatcctctg gggcaatacc ctgcccttca tcggtcacac tgattgaaag ctggtccttc
     9061 tccagcttag ccaccacttc cagcttggtt cctggagcag aatatttaaa agcgttatcg
     9121 accagattca ccaagatacg agaaagctta gcataatctc cctcaatccg ggcagactct
     9181 gggattacct gcaagtggac atctcttctc tcctgctcaa tcaaaaactg aaattcactc
     9241 atgcactcaa ttaagagctt gtccagaaaa atactgtctt tactggtagt ttccacctga
     9301 tttctagctg tgtttagggt caaaaaattc aactcctcaa ccagtttatt gagcctctcc
     9361 gtctggcgtc caatggttgc tagataatga gcttgctccg actccttgat aatcccatcc
     9421 aaaatccctt ctaccgtcgc ttgaatcgaa gtgatagggg tcttaatatc atgcgacaac
     9481 tgggcaatca tcaagccctt ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc
     9541 aaatcatggg acatctcatt aaaagtttgc cctaattgct gaaattctac aggaccttga
     9601 acctccaaat ttgaaggaaa atccttggcc gctacccgct tggcatgctc cttgagtttg
     9661 cccaacgacg taaagactgg caataggaga aagagactaa tcccagcacc gacaaggctg
     9721 gcaacgatgg tcatcccaag caaaaagtaa atctcgcctt tcgcaatcag cattttttga
     9781 acagcccaaa aaacaaccaa aatggttaag agggttgaaa taatatatcc aaccaaaata
     9841 taacttttta gtttcatgtt tgtcctctcg gtttctctat cttatatccc aacccccaaa
     9901 ctgtcttaat agtgggcgtt tggtcactac tatattttgc cagctcctgt cgaagagcat
     9961 ggatatgcac attcaaggta ttggtgtcat ccacgtagtc ttctttccag atcttttcat
    10021 agaggtctgt cttggagaaa actcgctctg gattgctagc taaaatccac agcaattcaa
    10081 atgatttaac agttaaatcc agcatttctt ctcctatttg aacttcatga ctactatgat
    10141 tcatttttag attgccaagg gaaatcagct ctgtttcgcc cccacgatga aggcggcgca
    10201 aaatattgtg gacacgcaaa actagctcac gtgggctaaa aggcttagca ataaaatcat
    10261 ctgctcccaa gctcaggccg taaatcttgt cctgttcact ggtcttagca gtaataaata
    10321 ggaaaggctg ctctggtgat aagtattgaa cctcactgat taaatcataa ccatccatcc
    10381 gaggcatcat gacatctgtg ataatcaaat caatcggttt tttcttgaac agctctagcg
    10441 cttccagtcc atcatgggct accaagacct gataacctgc ctgaattaag tatctctgat
    10501 gaatatctgt gatttctacc tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct
    10561 cctttgataa aaacagtgct atactgcttt aagtataaca ctatttttat tgttttacga
    10621 tgattttaat ctgctattga aagaaagtcc tgattgctga ttgagttgtt aaactaatct
    10681 tagtcagccc actatccatc atttatttcc ttagctgatt agttttcttc ttttttgttt
    10741 ttcaaaccta gaccaccgag taaacctgca agcgcaagcc caaggaaacc aatacttgcc
    10801 attgatgttt gagtctcacc agtatttggt agcatagctt tatcctctga catcatcgta
    10861 tcagacatct tgttagcaga agcagccatg ttttcacctg ccatcgtgtt ggtagaactt
    10921 gtcatggtgt cagcaggcat gctatctgta gtacctgtag catgattgtg attcatcgga
    10981 gtcacgccag aaccagagtt agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct
    11041 ttaacattta t
//
LOCUS       DAVLUM010000062        10850 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLUM010000062 DAVLUM010000000
VERSION     DAVLUM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10850
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.062"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            11..733
                     /locus_tag="VYN42_001633"
     CDS             11..733
                     /locus_tag="VYN42_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1462683.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            730..1578
                     /locus_tag="VYN42_001634"
     CDS             730..1578
                     /locus_tag="VYN42_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1462684.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            1610..2539
                     /gene="psaA"
                     /locus_tag="VYN42_001635"
     CDS             1610..2539
                     /gene="psaA"
                     /locus_tag="VYN42_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1462685.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            2662..3153
                     /gene="tpx"
                     /locus_tag="VYN42_001636"
     CDS             2662..3153
                     /gene="tpx"
                     /locus_tag="VYN42_001636"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1462686.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(3249..5957)
                     /locus_tag="VYN42_001637"
     CDS             complement(3249..5957)
                     /locus_tag="VYN42_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1462687.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQDQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSSTNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLITGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVVAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(5959..6660)
                     /locus_tag="VYN42_001638"
     CDS             complement(5959..6660)
                     /locus_tag="VYN42_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462688.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(6910..9321)
                     /locus_tag="VYN42_001639"
     CDS             complement(6910..9321)
                     /locus_tag="VYN42_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1462689.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYGFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTQFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDIAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGFVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            complement(9374..10066)
                     /locus_tag="VYN42_001640"
     CDS             complement(9374..10066)
                     /locus_tag="VYN42_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1462690.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFIGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(10517..10841)
                     /locus_tag="VYN42_001641"
                     /pseudo
     CDS             complement(10517..10841)
                     /locus_tag="VYN42_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3171 a         2503 c         2032 g         3144 t
ORIGIN      
        1 atacaagttt atgatacgta tcgaaaacct cagtgtctcc tacaaagaaa cgttggcact
       61 taaggatatt tcactagtgc tccatggacc aacaattacc ggcatcattg gtccaaacgg
      121 cgctgggaaa tcaacactat taaaaggtat gctgggaatt atcccacatc aaggtcaggc
      181 atttctcgat gacaaggaag ttaaaaaatc cttacaccga attgcctatg tcgaacaaaa
      241 aatcaatatc gactacaact ttcccatcaa ggtcaaggaa tgcgtctcgt taggactatt
      301 tccctctatt cctctctttc gaagtttaaa ggctaaacat tggaagaaag tgcaagaggc
      361 ccttgaaatc gtcggcctag ctgactacgc tgaacgtcaa attagtcaac tgtctggagg
      421 tcaattccag cgggtcttga ttgccagatg tttggtgcag gaagccgact atatcctctt
      481 ggatgaaccc tttgctggga ttgactctgt cagtgaggaa atcatcatga atacgctgag
      541 agatttgaaa aaagctggga agacggttct catcgttcac cacgacctca gcaagattcc
      601 ccactacttc gatcaagtct tacttgtcaa tcgagaagtg attgcctttg gtccaacaaa
      661 agaaactttt accgaaacca atctaaaaga agcttacggt aatcaactct ttttcaatgg
      721 aggtgaccta tgattgcaga atttatcgat ggattgcaaa aattccattt cctacaaaat
      781 gccttgataa cagctattgt cgtcgggatt gtagctggag ccgtgggatg tttcattatt
      841 ctacgcggga tgtcactcat gggagatgcc atttcacatg ctgtcttacc aggtgtagcc
      901 ctctccttca tcttgggcct tgacttcttt atcggagcca ttgtctttgg attgctagct
      961 gccatcatca ttacctacat caaaggaaac tcgattatca aaagcgatac cgccatcggc
     1021 attacctttt cttctttctt agccctcggt atcatcttga ttggtgtcgc taaaagttca
     1081 actgaccttt tccatatcct ttttggtaat atcctggccg tccaagatac ggatatgttt
     1141 attactatgg gtgtgggggc agccatcctc ttgttaatct ggattttctt caagcaactc
     1201 ttgataactt cctttgatga actcttggct aaagccatgg gaatgcctgt caatttctat
     1261 cactaccttc tcatggtact cctgactctc gtgtctgtga cagccatgca aagtgtcgga
     1321 actatcctga ttgtagccat gctgattacc ccagctgcaa ctgcttatct gtatgctaat
     1381 agtctgaaaa gtatgatttt cctttcctca accttcggag ctactgcttc agttttggga
     1441 ctctttattg gctatagttt taatgttgcg gcaggttcta gtatcgtgct tacagctgct
     1501 agtttctttc tcattagctt ctttatcgct cccaaacaac gatatttgaa actgaaaaat
     1561 aaacatttgt taaaataagg ggcaaagccc taataaattg gaggatctaa tgaaaaaatt
     1621 aggtacatta ctcgttctct ttctttctgc aatcattctt gtagcatgtg ctagcggaaa
     1681 aaaagataca acttctggtc aaaaactaaa agttgttgct acaaactcaa tcatcgctga
     1741 tattactaaa aatattgctg gtgacaaaat tgaccttcat agtatcgttc cgattgggca
     1801 agacccacac gaatacgaac cacttcctga agacgttaag aaaacttctg aggctgattt
     1861 gattttctat aacggtatca accttgaaac aggtggcaat gcttggttta caaaattggt
     1921 agaaaatgcc aagaaaactg aaaacaaaga ctacttcgca gtcagcgacg gcgttgatgt
     1981 tatctacctt gaaggtcaaa atgaaaaagg aaaagaagac ccacacgctt ggcttaacct
     2041 tgaaaacggt attatttttg ctaaaaatat cgccaaacaa ttgagcgcca aagaccctaa
     2101 caataaagaa ttctatgaaa aaaatctcaa agaatatact gataagttag acaaacttga
     2161 taaagaaagt aaggataaat ttaataagat ccctgctgaa aagaaactca ttgtaaccag
     2221 cgaaggagca ttcaaatact tctctaaagc ctatggtgtt ccaagtgcct acatctggga
     2281 aatcaatact gaagaagaag gaactcctga acaaatcaag accttggttg aaaaacttcg
     2341 ccaaacaaaa gttccatcac tctttgtaga atcaagtgtg gatgaccgtc caatgaaaac
     2401 cgtttctcaa gacacaaaca tcccaatcta cgcacaaatc tttactgact ctatcgcaga
     2461 acaaggtaaa gaaggcgaca gctactacag catgatgaaa tacaaccttg acaagattgc
     2521 tgaaggattg gcaaaataag cctctgaaaa acgtcattct catatgagct ggcgtttttt
     2581 ctatgcccac atttccggtc aaatcattgg aaaattctga ctgtttcaga tacaatggaa
     2641 gaaaaaagat tggagtatcc tatggtaact tttctcggaa atcctgtgag ctttacaggt
     2701 aaacaactac aagtcggcga caaggcgctt gatttttctc ttactacaac agatctttct
     2761 aaaaaatctc tggctgattt tgatggcaag aaaaaagtct tgagtgtcgt tccttctatc
     2821 gatacaggca tctgctcaac tcaaacacgt cgttttaatg aagaattggc tggactggac
     2881 aacacggtcg tattgactgt ttcaatggac ctaccttttg ctcaaaaacg ttggtgcggt
     2941 gctgaaggcc ttgacaatgc cattatgctt tcagactact ttgaccattc tttcgggcac
     3001 gattatgccc tcttgatcaa cgaatggcac ctattagcac gcgcagtctt tgtcctcgat
     3061 actgacaata cgattcgcta cgttgaatac gtggataata tcaattctga gccaaacttc
     3121 gaagccgcaa ttgcagctgc taaagcccta tagaaaaaat cctctgtcac aaagagttcc
     3181 ctgctctttg aaacggagga tttttgaata ttagtaaata gaagttcaat cagctaaaaa
     3241 taactacctt actctacaga tttcagggct tctaacatat caacctttct cagataataa
     3301 ttgacgaaga aaccaagcaa ggtcaaaatg atgcttactg ctaccactgg gattacatag
     3361 acttcccagc ctacctgcgg ataaaagaga atagtcgcag gcgaaatcat ttgaatcaaa
     3421 aattggtgta aatagaaacc agttatcaga ccaagtacga ttcccacaag ggacagcaca
     3481 atcgtctcac ggtaaatgta gagtgtgact tcattattat gaaaaccaag aaccttgata
     3541 gtggagagtt cacggattct ctcagctacg ttgatattgg tcagattgta aaggatgaca
     3601 atagctaata gaaccgatac gatgaccaag atggtcatgg tctgattgag tgagctagcg
     3661 atagagtcga agagtcgaat ggctgaagca ttttggacaa cgctagacac cgcagattga
     3721 ttcataagca agcccgcctg actttcgata ctagttgcac tggtatccct taatgagacc
     3781 agataagtgt tggcttgggg tagctgtccg taaagttgct catagctagc ctgactcata
     3841 taaataaagt gaccaacgta gttctcagta atagcagcga cctttagttc cttaccttca
     3901 atttctaaag tctgcccaac cttgacacct gccagctggg cgagtttagc tgtaataaca
     3961 atgccatctt ttaatgtcag ctcctgctga tgatgttgaa gatggataaa gggagtcaaa
     4021 tcttccttct ctatcatcat aagagtaatg ttttgaagac cagccttgcc tttgaaatcc
     4081 ttgtctagcg ttttagaata gattttctgg taggctagta tctcctgccc tttcaacact
     4141 tctgctagct ctaccttgtc ctgattggtc gaactaggat tttcagagac aagcatctga
     4201 tactgttgga tttgttgaaa ctgtttagac ggaactcctg ctacagaaga ttggattccc
     4261 aaacctgcaa agagcagagc tacagaacct gccacaccaa agattgtcat caacattctc
     4321 tgcttataac gaaagatgtt gcgggctgtt accttatgag taaaactgag acgacgccag
     4381 ataaaaccga tacgctccaa taagatttta gctcctttga caggaggttt aggaagtaga
     4441 agctgggctg cttcgtcatg aagttccctc caagccacca gataggctgg taacacactc
     4501 gccaaccagc tcaagacaag agctagtaag ctataggtcc aatagaactg aatctgggtt
     4561 tctcccacca ccatgccttt tgtaatgaca cttgaaatta cactggctag caaataatga
     4621 ccaagtatac tacctagagc cgttccgaca gtcccagcta ctagtccata aaggagaaac
     4681 ttggcgataa tatccttact acggtaaccc aaggccttaa aaatccctgc atgagttcgc
     4741 tcttcgtcta caaagcgagt catggtcgta aaggtcacca tggctgctac ggcataaagt
     4801 accacaggaa agatattgcc cactgctcga atactggatg aagcattgct atacataaga
     4861 tagccctgac cacctggcat ggtctgacga ttatagacct gataccttgg ctccgccaaa
     4921 tcgtccaaga cttgctgatg tttttctaat ttttcctttt cttgggctag attttgttca
     4981 gcttgcttta gtttgtcctc ttccttgccc aattcctgct tggcttgggt aagttgagca
     5041 ctagcctgct ctctctgaac ttgaggaaac aaggctagtt gactttcttg agcctgtata
     5101 cgagcttgag cagctgctaa acgacgcttg ccttcctgca aattagtctg agccttgtca
     5161 agggtctctt gccccttgtc tagagactct tgtccttctt ttttcaaaag ttgcagacgt
     5221 accttgccat tatctgataa agtttgttca aggtcttcct gatgttgctt ggatttttct
     5281 tcataagctg atgaaaaggc atttaaacct gctaaatctt gatatttcaa acgagctata
     5341 ttgtagactt tctgatcaaa ttgactaggt aaaatcaccc cataggctgt cagagtccca
     5401 cttccacttc ctgcgtagcc catatctcgc tgggagagga tttcagccga atccacaaaa
     5461 ccagtaatgg tataagtatg gtcttttaaa gaggaatgac cctcttcttt ttctttaaaa
     5521 ctaatctcct gtcccacgct gtattggtct tgcaaatgag tggccaaagc gatttccttg
     5581 tctgactgag gaagtcgtcc ctttcttagc tgaaaggttg aaattcgctc tggtttggag
     5641 tacagccgaa tggcatcctg cccattatcc atagtcacat ctgtcaaata gccaaactcg
     5701 acctctgcgc cctccgtctg ttttagttct tcttggtctg cttgatccaa gccatagtta
     5761 gacatgactg ccaaatccaa ggtttgagca gttgttaaat aagcattagc tgtcgcctcc
     5821 atgttgggac tggttacttt gaggcctact aaggctagag atcccaacat catcaggatc
     5881 aagatggata aaaaacgccc cttggagcct gtgaaggact gaattaagtc cttccaataa
     5941 gtttttcgct tgatcatgct agtactccaa actgtcaata tcctgaggat gctggttgag
     6001 caccacatcc ttgacactgg catcgtgcat atgaatcacg cgatcagcaa tgggcgccaa
     6061 agctccatta tgagtcacga tgatcaccgt cgctcccttt tgacgagaca tatcttggag
     6121 aattttcaaa acctgcttgc ccgtctgata atccaaggct ccagtaggtt catcacaaag
     6181 aagaatttta ggatttttgg ctaccgcgcg tgcaatggag actcgctgtt gctcccctcc
     6241 agaaagctgg gctggaaagt tatttagacg atgagccaga cctacatctg tcaagacctg
     6301 atcaggattc aaggcatctg tcacaatttc agaagccagt tccacatttt ccttagctgt
     6361 cagattagaa actagattat aaaactgaaa aacaaacccc acatcatttc tacggtaatt
     6421 ggtgcgctgg tgggaactat aatccgcaat attaacacca tcaatccaga tttccccttc
     6481 atcattggta tccattcccc caagaaggtt gagaactgtt gacttgcctg cacctgaagc
     6541 accaaggata ataaccagct cccccttttc aatctcaaaa ttcacatcac gattagccac
     6601 aatctccgtg tccccaacct gataacgctt gtaacagtgt ttcatctcaa tataagccat
     6661 cagacccacc ctctatcaaa caaattatac tcctcgaaaa tctctcttca aaccacgtca
     6721 gcttccatct gcaacctcaa aacactgttt tgagcaacct gcggctagct tcctagtttg
     6781 tgctctttga ttttcattaa gtattacttc ctattatcat tataacgctt tttcaactag
     6841 ttggaaactg cctatattct taaatcctta ttaaaaggaa gtttcaaatt actgccttat
     6901 aacatcttct taaaaataaa attgaacaag atcaccttct gctgttgcca ccgaaataca
     6961 atctttcccc atgcatttcg cttttatttt ttcttgattc attttaatca cactcttctc
     7021 aatatctgga taagaaactc gcaaatctcc tccactcctt gataaaatgg tcaactgtaa
     7081 gagtttttta tcttcccagc tcatgctcac ttcaaaatgt ccacgtgcca ttaagcctga
     7141 aacaaaacct gttgaccaag catcaggtag ggcagctaga ggtaccagat aagctgcatg
     7201 agactggagt aacatttctg ccatgccact agtagcacca aaattaccat ctatctgaaa
     7261 aggaggatgg ctacaccaaa gatttggcaa ggtggatgtc tttaactgct ctgccaataa
     7321 tttatgggct cgattgccat ctcccaaacg cgcccagaga ttgatcttat tagccttgga
     7381 ccagcctgtg ccgccatctc cacgatcatt gaggctagca cgcgccgctt caatatactc
     7441 ttgtcccttg tagctaaaga gattgccagg atagagtccc actagatggg aagcgtgccg
     7501 gtgctgggcc tccactttct cattttgaaa atactgctct tcctcctcat accactccct
     7561 gattcgacca gattgagtga tttgcaaagg atttagtaaa tcagacttct ccttaacctc
     7621 agtcaacaag tcctcatcca gtcccaattc ctgagcagcc tgaataaaat catgaaataa
     7681 ctgccaaatc agagattggt cataagtatt gccaatcgaa atcggcccat gttctgggga
     7741 ataagacgga gaagacaccc aacgctgcgc ctgctgatcc ttatgtaaaa aggcattcca
     7801 aaaacgaacc gtttccctca acatgggata aattttctcc ctgagatagt cttggtccct
     7861 ataaaatgaa taggcttcat aaacggtttg catcatccac gcattggcag ctggtgacca
     7921 accccaatag taatcccaac caggtgccgt ccaaccaaag ggagtcgctt gagtatgaac
     7981 caaccaacca ttctcctcac ctttctgaga gacgattcct gcatacttta cagccgctag
     8041 acgaccatag acacgcaaat catctacata gttgatgact ggaaagaccg tctctagaag
     8101 attggtaaca taggctggcc aataattcat ctgcagattg acatttaagt gatagtccga
     8161 attccaagga ggattgtcga ccgcattcca gactccctgt aggttagctg gtagagcatc
     8221 tgggcagtct ctggacgaac taatcaataa ataccgtcca tactggaaga acagctcctc
     8281 caaagcctgc ccttcttgtg gcttataatt ttttaacaaa tcatctgtag tggatgcgtc
     8341 aacatcagct tccaaatcca attgaacacg ctggaataag gcttggtagt cctcgatatg
     8401 ccttgatttc aattgggtat agcccttttc tttagctatg tccaccaagt ctatcacctg
     8461 ttgctctaaa tctagtttct tgcgataatt gctagcagga ttttgggcaa aatccgtctt
     8521 agcggccaag aagagattgg cataactggc tcctgatatc tgaaccctat ctgaccaaac
     8581 tctaatatct ccatccgttt cccaagctag ataactagca aaccgcagat cattatcctt
     8641 aactcttccc ttcatcaaga tatgagaatc agtaatatcc aacttacact ccttgtaatc
     8701 agatttttcc tgctcatact ttccatcaga agccaaatca caggtcaagg atagttctat
     8761 agtaaaatct agagtttcca acccttcctt agtaaaacat tgaaccaaga gatcatctgg
     8821 aaaactcgca aaagcttcac gttcaaattg cgttccctta tagacataag aagtcgtcgc
     8881 aagtgcctta ctaatattca gctgtctctg atagtccgtc acctgagaca aagtcgtacc
     8941 ttgctggctg aactcaatgt gaatatcccc aaaagacaga taggtcccat attgactcgt
     9001 ttttggccca attaggtgct gctcagccag ttccttagcc agattgtaat ctctcttctc
     9061 caaagcctgc cgaatctcag ctaaaaaacc atactgatcc tgaagatttc caccctgata
     9121 atctgaacta tcaggaagtg gacctccaga ccagagactt ttttcattaa attgaatccg
     9181 ttcagcccct ataaggccaa atacttttgc tcctaaagaa ccattgccta tcggtaaagc
     9241 ttcttcttcc caacccatgt aagtggttga agctggttgc ttgtaggcca gtacataatc
     9301 ttgtttttta ttccttatca tacttccata ctaacataaa aagcctagaa atcaatccta
     9361 ggcttacaat tttttatttt ccaaggtaat attcagaaac gacgttcaat ttttcgtcga
     9421 attcgaatac caatggtggg aagttaggga tttccacgtc catgatctcg tcatctgaca
     9481 aacctttgat gtgttttaca agggcacgga ttgagttacc gtgagctcct atgaatacgt
     9541 ttttaccatc tttaagagct ggagcgattt tatcttccca gaatggaaga gcacgttcca
     9601 aagtcacttt caagttttca gcatctggga ttactgagtc gtcaagtgaa gcataacgac
     9661 ggtctgtgtg agctgagtgc tcatcatcac ggtccatatt tggaggcaat acatcgtatg
     9721 aacgacgcca gatgtgaact tgctcatcac caaattgttc agcagcttca gctttatttt
     9781 taccagtcaa accaccatag tgacgttcgt tcaagcgcca tgatttttca actggaaccc
     9841 acaattggtc agaagcttca agagccaagt tagttgtttt gatagcacgt ttcaatactg
     9901 aagtgtaagc ttggtcaaat ttgataccag cttctttgat caatttacca gcgtcaatcg
     9961 cttgttgtgt acctttttca gacaaatcaa catcagccca accagtgaaa aggttagctt
    10021 tgttccattc agactcaccg tggcgagcaa aaaccaattt taccattaga tggattctcc
    10081 tttaaatttt ccgaggtttc ccctcgttta tctattctat tttacacaat ttttcacaaa
    10141 aaagctagtc aaaaccaaaa aggaaaggac tgtttggcaa tcacattgtt tttggttgtt
    10201 tctattctat cttcattatt taaccttttt ttctgcgcat cgaataattt ttgagttgac
    10261 tcttttagtt tagtaaacga gtcattattt tccatagcta tgcctttgaa accttcctca
    10321 gctttagtaa aataatcatc aaaaatattt ttataaagat ctatataatc tgcataagtg
    10381 cgtattgatt caatcgcatc gtctgttaca accggtgtat cgaaagtgat tgtttctttt
    10441 gaactattgg atgttgctac tgtcttctca tcattacttg ttgaagtatt ctttgaactt
    10501 tatgttccac atgcaactag aatagagatc ctccgataat agcaagaatc cccccaaccc
    10561 atcctaagaa tggaatgaga ctaactccac cagaaacaat cattagtaca gacggagctg
    10621 cacctacacg cttatctcct ttatagtaaa caatagcaat gataccaaga acaagatttg
    10681 caatcttcaa ggcattcaag agtaaggcaa cacctgaaaa agcccctgca gtagctcctc
    10741 cattaagagt tgtagcagct gtgtttaccg ctgttcccaa caagacaaaa ggaccaagta
    10801 agaagtaaaa ttcctcccac aagaccgacg ataccactaa ttaaagcaag
//
LOCUS       DAVLUM010000063        10811 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLUM010000063 DAVLUM010000000
VERSION     DAVLUM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.063"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            101..598
                     /locus_tag="VYN42_001642"
     CDS             101..598
                     /locus_tag="VYN42_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1462691.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            598..2253
                     /gene="dnaX"
                     /locus_tag="VYN42_001643"
     CDS             598..2253
                     /gene="dnaX"
                     /locus_tag="VYN42_001643"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1462692.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLPALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2281..2475
                     /locus_tag="VYN42_001644"
     CDS             2281..2475
                     /locus_tag="VYN42_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1462693.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2625..3395
                     /gene="sufC"
                     /locus_tag="VYN42_001645"
     CDS             2625..3395
                     /gene="sufC"
                     /locus_tag="VYN42_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1462694.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3423..4685
                     /gene="sufD"
                     /locus_tag="VYN42_001646"
     CDS             3423..4685
                     /gene="sufD"
                     /locus_tag="VYN42_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1462695.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4696..5922
                     /locus_tag="VYN42_001647"
     CDS             4696..5922
                     /locus_tag="VYN42_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1462696.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5909..6340
                     /locus_tag="VYN42_001648"
     CDS             5909..6340
                     /locus_tag="VYN42_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000009523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1462697.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQ"
     gene            6403..7815
                     /gene="sufB"
                     /locus_tag="VYN42_001649"
     CDS             6403..7815
                     /gene="sufB"
                     /locus_tag="VYN42_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1462698.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8046..9287)
                     /locus_tag="VYN42_001650"
     CDS             complement(8046..9287)
                     /locus_tag="VYN42_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1462699.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIIQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9390..10499
                     /locus_tag="VYN42_001651"
     CDS             9390..10499
                     /locus_tag="VYN42_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1462700.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3204 a         1975 c         2341 g         3291 t
ORIGIN      
        1 gggatttacc cactacaaat attatagagc ccaaaatcct ttgtttacta aacaagggat
       61 ttttcttttg tctctgctcc ttttttgata taatagttct atgttaaaat cagaaaaaca
      121 atcacgttat caaatgttaa atgaagaatt gtccttccta ttggaaggcg aaaccaatgt
      181 tttggctaat ctttccaacg ccagtgctct cataaaatca cgttttccta ataccgtatt
      241 tgcaggcttt tatttgttcg atggaaagga attggtttta ggccccttcc aaggaggtgt
      301 ttcctgcatc cgtattgcac taggcaaggg tgtttgtggt gaggcagctc actttcagga
      361 aactgttatt gttggagatg tgacgaccta tctcaactat atttcttgtg atagtctagc
      421 taaaagtgaa attgtggtgc cgatgatgaa gaatggtcag ttacttggag ttctggatct
      481 ggattcttca gagattgagg attacgatgc tatggatcga gattatttgg aacaatttgt
      541 cgctattttg cttgaaaaga caacatggga ctttacgatg tttgaggaaa aatcttaatg
      601 tatcaagcac tttatcgaaa atatagaagt caaaacttct cccagttagt tggtcaagaa
      661 gttgtggcta agactcttaa acaagcggtg gagcaagaga aaataagtca cgcttatctt
      721 ttttctggtc ctcgtggaac gggaaaaacc agtgttgcta aaatctttgc caaggctatg
      781 aactgtccca atcaagtggg tggcgaacct tgcaataact gctatatttg tcaagcagtg
      841 acggacggta gtttagaaga tgtcattgaa atggatgcag cttctaataa tggggtagat
      901 gaaattcgcg aaattcgtga taaatctacc tatgcgccta gccttgctcg ttataaggtt
      961 tatatcatag atgaggttca catgctgtct acaggggctt ttaatgccct cttaaagacg
     1021 ctggaagaac caacacagaa tgtagtcttt attttggcca ctactgaatt gcacaagatt
     1081 cctgctacta ttctatcccg tgtgcaacgt tttgagttta aatcaattaa gacacaggat
     1141 attaaggaac atattcacta tatcttagaa aaagaaaata tcagttctga accagaggct
     1201 gtggaaatca ttgccagacg ggcggaaggt ggaatgcggg acgccttgtc tattttggat
     1261 caagccctga gtttgacaca gggaaatgag ctgacgactg ctatctctga agaaattact
     1321 ggcaccatta gcctaccagc cttggatgat tatgtggcgg ccttgtctca acaggatgtt
     1381 cccaaagctt tgtcttgctt gaatcttctt tttgacaatg gtaagagcat gactcgtttt
     1441 gtgaccgatc ttttgcacta tttaagagac ttgttaattg ttcaaacagg gggagaaaat
     1501 actcatcata gttcagtctt tgtagaaaat ttggcacttc ctcaaaaaaa tctgtttgaa
     1561 atgattcgct tagcaacagt gagtttagca gatattaagt ctagtttgca gcccaagatt
     1621 tatgctgaaa tgatgaccgt ccgtttggcg gaaatcaagt ccgaaccagc tctatcagga
     1681 gcggttgaaa atgaaattgc tacgctgaga caggaagttg cccgtctcaa acaagagctt
     1741 tctaatgtag gtgcggttcc taaacaagtt gcaccagctc ctagtcgacc agctacgggc
     1801 aaaacagtct atcgtgtcga tcgcaataaa gtgcaatcta tcttacaaga ggccgtcgaa
     1861 aatcctgatt tagcacgtca aaatttaatt cgtttgcaga atgcctgggg agaggtaatt
     1921 gaaagtctag gtgggccgga caaggctctg ctagctggtt ctcaaccggt tgctgccaat
     1981 gaacaccatg ctattcttgc ttttgagtct aacttcaatg ctggtcaaac tatgaaacga
     2041 gacaatctca ataccatgtt tggtaatatc ctcagtcagg cggcaggttt ttcacctgag
     2101 attttagcta tttccatgga ggaatggaaa gaagttcgcg cagccttttc agccaaagcc
     2161 aaatcttctc aaactgaaaa agaagtagaa gaaagcctga ttccagaagg atttgaattt
     2221 ttggctgata aagtgaaggt agaggaagac taaagaaaga tttcatgata caataagttt
     2281 atgaataaac aacaatttat tattatggcg ctatttacag ctgctgagac ctattttttc
     2341 aatgaagcct ggatgactgg ccgctatatt atggcagcct tttgggcaat tttactcttt
     2401 agaaatttcc gagtcagtta tgtgatgggt aaaatcgttg atgtcatcga tcagcatttt
     2461 aataggaaag actagccctc agcttccaga caaaatcaaa gccttttagg cttttttttg
     2521 ttatactaga aaagtatatt tatagaattt ttgctctatt tctggggaaa tcagacgttt
     2581 ttctagtaag tactgtaaaa gttttgaaaa agaaaggaac tatcatgtca gtattagaga
     2641 tcaaagatct tcacgttgag attgaaggaa aagaaatttt aaaaggggtt aacctgaccc
     2701 tgaaaacagg agaaattgcc gctatcatgg gaccaaatgg tacaggtaaa tcgactcttt
     2761 ctgccgctat catgggaaat ccaaactatg aagtaactaa aggtgaagtt ttgtttgatg
     2821 gcgtaaacat ccttgagttg gaagtggatg agcgtgcgcg tatgggactt ttccttgcta
     2881 tgcaataccc atcagaaatc cctggaatta ccaatgctga gtttcttcgt gccgctatga
     2941 atgcgggtaa agaagatgat gagaagattt cagttcgtga gtttattact aagctagatg
     3001 aaaaaatgga attgctcaac atgaaagaag aaatggcaga gcgttacctc aacgaaggct
     3061 tctctggtgg tgagaaaaaa cgcaatgaaa ttcttcaact tttgatgttg gagccaacat
     3121 ttgctctttt ggacgagatt gactcaggtc ttgatattga cgctcttaaa gttgtgtcta
     3181 aaggtgtcaa tgccatgcgt ggtgaaggtt ttggtgctat gatcatcact cactaccaac
     3241 gtcttttgaa ctatatcaca cctgatgtgg tacacgtgat gatggaaggt cgtgttgtcc
     3301 tttctggtgg tccagaattg gctgcgcgtt tggaacgtga aggatacgca aaattagctg
     3361 aagaacttgg ctacgactac aaggaagaat tgtaattccc tcgtatcttt taggagaagt
     3421 aaatgactag agaaaatatt aaactttttt cagaaatgca cgctgaacca agctggttgg
     3481 ctgatctccg tcaaaaagct tttgacaaga ttgagacttt ggaattacca gttattgagc
     3541 gtgtcaaatt ccaccgttgg aatctgggtg atggaacgat tacagaaaat gagccatcag
     3601 caaatgttcc agatttcaca gctttagatc atcacttgaa gttggtgcaa gtaggaactc
     3661 aaactgtttt cgaacaaact ccagttgagt tagctgaaca gggtgttgtc ttcacagact
     3721 ttcactcagc tttagaagaa attccagagc tgatcgaaga attcttcatg tcatctgtta
     3781 agtatgatga tgacaagttg gcggcttacc acacagctta ctttaacagt ggtgctgtac
     3841 tctatattcc agataacgta gaaatcacag agccaattga aggaattttc taccaagata
     3901 gcgatagcaa tgtgccgttt aacaagcata ttatgattat cgctggtaaa aattctaaga
     3961 ttagttatct ggagcgttta gagtcacgcg gtgaaggaag tgacaaagta actgccaata
     4021 tcacagtgga agtgattgca cgttctggtg cgcaagtcaa gtttgctgct atcgaccgtc
     4081 taggtgaaaa cgtcactgcc tacattagcc gtcgtggtaa attaggcaac gatgcaagta
     4141 ttgactgggc tatcggtgtc atgaacgaag gaaatgtcgt tgctgatttt gatagtgact
     4201 tgattggtaa tggtagccat gctgacctca aggttgtagc tctttcaagt ggtcgtcagg
     4261 tacaagggat tgatactcgt gtaactaact atggctgcaa ctctatcgga aatatcctac
     4321 aacatggggt tatccttgaa aaagcaactt tgactttcaa tggtatcggc cacatcatca
     4381 agggtgctaa gggagcagat gcgcaacaag agagccgtgt tctcatgctt tcagaccaag
     4441 cgcgttcaga tgctaaccca attcttttga ttgatgaaaa tgatgtcact gcaggacacg
     4501 cagcgtctat cggacaagtt gatccagaag acatgtatta cctcatgagt cgtggattgg
     4561 ataaggcaac tgcagagcgt ttggttgttc gtggtttcct tggatctgtt atcgtggaga
     4621 ttccagtcaa ggaagttcgt gatgaaatga ttgcaactat cgaagagaaa ttgtcaaaac
     4681 gctaagggga agcctatgtt agatgtagaa gcgattcgca aggattttcc aattttagat
     4741 cagattgtca atgatgaacc tctggtctat ctggacaatg ctgcgacgac acaaaaacca
     4801 ctagtagttc tgaaagctat taacagttac tatgagcagg acaatgccaa tgttcaccgt
     4861 ggtgtccata ccttagcgga acgagcgaca gcttcttatg aagctgctcg tgaaaccatt
     4921 cgtaagttta ttaatgcagg ctctacaaag gaagttctct ttaccagagg aacgacaacc
     4981 agccttaact gggtggcacg ctttgctgag gaaattctcg ctgagggaga ccaggtcttg
     5041 atttcagtaa tggaacacca ttctaatatc attccatggc aggaagcttg tcgaaagact
     5101 ggagcagagc ttgtctatgt ctatcttaaa gacggtgcct tggatatgga ggatttgcga
     5161 gctaaattga ctgataaggt taaatttgtt tccctagctc atgcctccaa tgttcttggt
     5221 gtgatcaatc cgatcaagga aatcactcaa ttagcccacc aagttggggc aatcatggta
     5281 gtggatggtg ctcaatctac acctcatatg aagattgatg tccaggactt ggatctggac
     5341 tttttcgcct tttcgggtca caagatggct ggtccgactg gtatcggtgt cctttacggc
     5401 aaagaaaagt atcttgagca aatgtctcca gtagaatttg gcggcgagat gattgatttt
     5461 gtctacgagc aatttgctag ttggaaggaa ttgccttgga aatttgaggc tggaacgcca
     5521 aatatggcag gagctattgg acttgcgact gcagttgatt atctggaaaa gattggtatg
     5581 gatgccgttg aagctcatga acaggaattg attgcgtacg tctatccaaa actgcaggca
     5641 attgagggat tgaccattta cggttctcag gatttggctc aacgttcggg tgttattgcc
     5701 tttaacctag gtgatctcca tcctcacgat cttgcgacgg ctctggatta tgaaggagtg
     5761 gctgttcgtg ctggtcatca ttgtgcgcaa cccttgcttc agtatttgga agtcccagca
     5821 acagctcgtg caagttttta tatctacaat accaaggcag attgcgacaa actagtcgat
     5881 gccctacaaa agacaaagga gtttttcaat ggcactttct aaactagata gcctttatat
     5941 ggcagtggta gcagaccatt cgaaaaatcc acatcaccaa gggaagttag aagacgctga
     6001 gcaaatcagt ctcaacaatc cgacttgtgg ggatgtcatc aacctctctg tcaagtttga
     6061 tgcagaggac cgtttggaag atattgcttt tctaaattca ggatgcacga tttcaactgc
     6121 ttctgctagt atgatgacag atgccgtttt aggaaaaacc aaacaagaaa ttttagaact
     6181 ggcgactatt ttttctgaaa tggttcaagg gcaaaaagat gagcgtcaag accaacttgg
     6241 agacgcggca ttcttgtcag gtgttgccaa attccctcaa agaatcaagt gtgcaaccct
     6301 agcttggaat gcccttaaga aaacaattga aaatcaataa aaacagtaag acaagtttct
     6361 tttgtcttat gaattattag aaatgaagaa agaaaggata ttatggctga agaaagagta
     6421 gaaccaaaac caattgacct tggtgaatat aaatttggtt tccatgacga tgtagagcct
     6481 gtcttatcga caggaaaagg actcaacgaa ggtgttattc gtgaattatc tgctgctaag
     6541 ggtgagcctg agtggatgtt ggagttccgt ttgaagtctt atgaaacctt caaaaaaatg
     6601 cccatgcaaa cttggggagc agacttgtca gagattgact ttgatgactt aatctactac
     6661 caaaaaccat ctgacaaacc agcccgttct tgggatgatg tacctgaaaa gattaaagaa
     6721 acctttgaac gtatcgggat tccagaagct gaacgtgctt atttagcagg ggcttctgcc
     6781 cagtacgagt cagaagtggt ttaccacaac atgaaggaag agttccaaaa attaggtatt
     6841 atctttacag atacagattc cgcactcaag gaatacccag acttatttaa acaatacttt
     6901 gcgaagttgg taccgccgac agataacaag ttggcagccc tcaactcagc agtatggtcg
     6961 ggtggaactt ttatctacgt gccaaaaggt gtcaaggtag atattccact tcaaacttat
     7021 ttccgtatca ataacgaaaa tataggtcag ttcgaacgta ccttgattat cgttgatgag
     7081 ggagcaagcg tccactacgt agaaggatgt acagcaccaa catattcaag caatagcttg
     7141 cacgctgcca ttgtagaaat ttttgctttg gacggagctt atatgcgtta tacaactatc
     7201 caaaactggt ctgataacgt ctataacttg gtaacaaagc gtgctaaggc tcaaaaggat
     7261 gccactgttg agtggattga tggaaacttg ggtgccaaaa cgactatgaa atatccatct
     7321 gtttaccttg atggagaagg agcgcgtggt accatgctct ctatcgcctt tgctaatgca
     7381 gggcaacacc aagacacggg tgctaagatg attcacaatg ctccacatac cagctcgtct
     7441 attgtgtcta aatccatcgc taaaggtgga ggaaaggttg actaccgtgg acaagtcacc
     7501 tttaacaaga actctaagaa atctgtttcc cacattgaat gtgataccat tatcatggat
     7561 gacttgtcag catcagatac tattccattt aatgaaattc acaactcgca agtggctttg
     7621 gaacacgaag ccaaagtatc taagatttca gaagagcaat tgtattatct catgagccgt
     7681 ggattgtcag aatctgaggc aactgaaatg attgtcatgg gatttgtaga accctttaca
     7741 aaagaacttc caatggaata cgcagttgag ctgaaccgct tgattagcta tgaaatggag
     7801 ggatcagttg gataaaattt gattttatac tcttcgaaaa tctcttcaaa ccacgtcagc
     7861 atcgccttac cgtatgtatg gttactgact tcgtcagttt catctacaac ctcaaaacag
     7921 tgttttgagc aacctgcggc tagcttccta gtttgttctt tgattttgag tattagattt
     7981 actcaaaatc aaggattttg aagatgaact tgtatcaaaa aatcgcggtt taaaatcgcg
     8041 attttttata atttctcgtt aacaaagcgg acaaactgat tccaccaaac ttttaagaag
     8101 aaggcttttt caattttctt gtctgctacc atttcgaaac tagggcgctc tgtggtgatg
     8161 taaccttgac caatcaagtc cttgtcttca taagtcaaat ggccaaccac tgttccagct
     8221 tcaagtggtg ctgggattgc tttggaatca ggtgtgaatt gaacagattg ggaagattga
     8281 ttcccaacac gttcgattag atagatatcc tctggagcca ctgcagttac tgtatcttct
     8341 tttccatctt gtacaggggc tttgctatct tgataggcat cgccttgttg aatgattttg
     8401 cgaagtgtaa atgtagaaga aatataatcc attagggaag atgtagctgt aaatcgagcg
     8461 taaggattat tgtcttgatg atctgcattt aaaacaactg tgatgactct catgcctttt
     8521 tcgacagtag taccaacaaa agactctcca gccttatctg ttgttcctgt ttttagccca
     8581 tcaaaaccac cacggtaagc aggcatacct tctaacatgt agttggttga agtgattgtc
     8641 atcccagcaa aagtagaaga aggttttttg gtgatttcta agacttgtgg gtattttttg
     8701 atgaggttgc gagcaacgat agcgacatca taagcactaa gcttattttc ctcatctttt
     8761 ttagaacctg ggtaaatgtt atcccctaga gtttcattgt taagacctgt cgtattgaca
     8821 acagtggcat cctgaattcc ccattccaag agttttgccc gcatcatatc gacgaaatct
     8881 ttttctgagc cagcaatttt ctcagctagg gcaatagcgg cgctgttggc actagatacc
     8941 agagttgctt caagcaactc ttcgacagta taattacggg cctccatagg aatattactg
     9001 gcttcagaat ttgtcgtcaa ttgataagga taatcagaaa tatctacagg agtggagagg
     9061 gtaatacttc cgttttccaa agcttcatag accagataaa cagtaatcaa ttttgttatg
     9121 gaagcaattt cgacaggttg cgttgcatcc ttctcataga gaattttacc agtatttgcc
     9181 tcaacagcaa tcgcatgttt agcggcaatg gtaaaatctt gagcaacagc agtagaagca
     9241 ccccctaaaa gagagacagt taacaaagtt aaaaatattt ttttcatagt agtcttattc
     9301 tatcataaag aaaaaaaata ttcttgcttt aataattcat ctgttaagct ttttgaaaat
     9361 atggtaaaat aaagtgaggg aggtaactca tgtttcgtag aaataaatta tttttttgga
     9421 ccacagaaat tttactctta accatcatct tttacctatg gagacagatg gggtctttga
     9481 ttaacccttt tgttagcgtg cttaatacaa ttatgattcc atttttatta gggggctttc
     9541 tttattattt gacaaaccct attgttactt tcttaaataa agtctgtaaa ctcaatcgtt
     9601 tgcttggtat tttaattacc ttgtgtactt tggtctgggg aatggtcata ggtgttgtct
     9661 atctcttacc tattttgatt aatcagttat ctagtttgat tatatctagt caaactattt
     9721 atagtcgagt acaagactta atcatagact tatctaatta tcctgcgctc cagaatttgg
     9781 atgtagaagc tacaattcag cagttaaact tatcctatgt tgatattctt caaaatatcc
     9841 taaatagcgt atcaaatagt gtggggagcg tcttgtcagc tcttatcagt actgttttga
     9901 ttttgattat gactccagtt tttttggttt atttcttatt agatggacat aaattcttgc
     9961 ccatgcttga aagaacgatt ctaaagaggg atcgcttgca tattgcaggc ttattaaaga
    10021 atttaaatgc gacgattgct cgctatatta gtggagtttc gattgacgca atcattatag
    10081 gttgtttggc ttatattggc tatagtatta ttggtttaaa atatgcttta gtttttgcca
    10141 ttttttctgg tgtagccaat ttaattcctt atgtggggcc aagtattggt ttgattccta
    10201 tgatcatcgc aaatatattc actgatcccc atagactgct gattgcagtg atttatatgc
    10261 ttgttgttca gcaggtagat ggcaatatct tatatcctcg aatcgtagga agtgttatga
    10321 aggttcatcc aatcacgatt ttagttttac ttttgttgtc aagcaatatc tatggtgtag
    10381 ttggaatgat tgtcgcagtg ccaacctatt ctatcttgaa agaaatttct aagttcttat
    10441 cccgtttgta tgaaaatcat aaaataatga aagaacgaga aagagaatta gctaagtaaa
    10501 agtcaggaga accctgattt ttctttactg gaagtggcct ttagattaga agactgaaaa
    10561 taagttaaag tcttaaacta attttcacag ctaagaatag tagaagttaa tctgataaaa
    10621 atcgaaaaaa ccagtggaat tccgtgtcag ggtaagttcc actggttttc atagtctatt
    10681 aaagttcgaa tgaaacctat ttatagtata ttgaaactag aatagtacac ctctaattct
    10741 aaaacattgt tagaaatcga tttgactgtc ctgatctatt cgtcctattc ttatttcatt
    10801 ttactatatt t
//
LOCUS       DAVLUM010000064        10758 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLUM010000064 DAVLUM010000000
VERSION     DAVLUM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.064"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(117..1541)
                     /locus_tag="VYN42_001652"
     CDS             complement(117..1541)
                     /locus_tag="VYN42_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1462701.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="VYN42_001653"
     CDS             complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="VYN42_001653"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1462702.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="VYN42_001654"
     CDS             complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="VYN42_001654"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1462703.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6528..7706)
                     /locus_tag="VYN42_001655"
     CDS             complement(6528..7706)
                     /locus_tag="VYN42_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1462704.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEEAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7786..8649)
                     /locus_tag="VYN42_001656"
     CDS             complement(7786..8649)
                     /locus_tag="VYN42_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1462705.1"
                     /translation="MEHLGKVFRKFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEYSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8652..10553)
                     /locus_tag="VYN42_001657"
     CDS             complement(8652..10553)
                     /locus_tag="VYN42_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1462706.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3241 a         2364 c         1906 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaattcct
      181 tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaaag gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa ttttttcctt atcacgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcagag ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc aaaatttttg
     1621 agattatttt cacaaacttg atttttcaaa gtatactcaa taaaaattaa aaaaatccac
     1681 tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
     1741 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagccaaacc aatttctcac
     1801 aatgtttcag aaacaagggt gtgctattcc aatttcagcc tactataact gtcatagatt
     1861 gctgaaacaa agtctaggta aaagtcttca taataaaaag acctcctatc aagtgttcaa
     1921 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
     1981 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt actaatactc
     2041 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
     2101 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttaccaa
     2161 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
     2221 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
     2281 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaagg caccagtttt
     2341 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
     2401 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
     2461 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
     2521 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
     2581 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
     2641 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     2701 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     2761 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     2821 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     2881 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     2941 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     3001 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     3061 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     3121 ggtaccatct ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     3181 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     3241 ataagcttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     3301 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     3361 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     3421 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     3481 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     3541 tttagtcaaa tcacgaatat gcatttcaca gataactgcc ttacatggat tttccaagcg
     3601 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     3661 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     3721 tgtttggtga tgagggaatt ggacttgata ctgataagtc ttacctacca aatcttcttc
     3781 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     3841 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     3901 aacttgcact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     3961 acggcaaccc aattctcctt ggtaacccca atgatgatca aaactagcac tgttaatggc
     4021 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     4081 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     4141 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     4201 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     4261 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     4321 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     4381 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     4441 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     4501 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     4561 taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac ccagactttc
     4621 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     4681 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     4741 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     4801 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     4861 agacagattt tcaattgaat ggaaatattg aagtaaaagc tgactagcct tgcttccgac
     4921 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     4981 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     5041 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     5101 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     5161 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     5221 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     5281 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     5341 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     5401 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     5461 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     5521 agcagggaac ttgtaggcta ctgcccactt tggagcctta acggtaaaac caagttcttc
     5581 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gtagattttc
     5641 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     5701 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     5761 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac gcttggcaac
     5821 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     5881 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     5941 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     6001 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     6061 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     6121 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     6181 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     6241 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     6301 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgaaaccga
     6361 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     6421 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     6481 gcggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     6541 tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac accacttcca
     6601 attatcagga aagaagagag atgtacactt tgcaagactg tcataaatcc ttttgcaata
     6661 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctctcccaag aaattcgctc
     6721 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     6781 caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     6841 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     6901 gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact tgcataggct
     6961 tcttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     7021 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     7081 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     7141 acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa aaaagtcagc
     7201 gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa ggaaagaaca
     7261 ggagagctaa cacctacaac ctgcaaaacc agctctaagc gagaattata gatcacaatc
     7321 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     7381 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     7441 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     7501 cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgagaat agatgtgacg
     7561 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaac
     7621 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     7681 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     7741 tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     7801 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     7861 atgcatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     7921 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     7981 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatact ctaaacaatg
     8041 ctggtaacaa ttgagggcca aaatcaaaac taatctctta tggcgactaa tctcttggta
     8101 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     8161 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagag
     8221 ataatctgct accttatcca aatcatcctg cttcatatca taagtcgcat ctctttgaca
     8281 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa agggaagtcg tcgaactctt
     8341 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     8401 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     8461 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     8521 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     8581 tgctgcttcc tttaaagaat aatttccact tgttcgaaat ttacgaaata cttttccaag
     8641 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     8701 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     8761 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     8821 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     8881 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     8941 ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag gtagagagtt
     9001 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     9061 tgactgacaa aaagcaaggt accatcaaag tcaatcaagg cattttctag cacttcctta
     9121 ctatcaatat ccaagtggtt ggtcggctca tccagaatca aaaagttatt gttttccata
     9181 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     9241 ttaacatcat ctcctgagaa aaggaaggcc ccaagacggt tgcggatttc aacttctggt
     9301 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     9361 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc acctttgata
     9421 aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc atttggacca
     9481 acgatagcga cagcattcat cttacgaaga tctaggttga taggttgtga caaaacttcc
     9541 ccgtcataac caatagcagt attttcaaca gtcaaaacaa cattgcccga cgttttttca
     9601 gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa acgctccatt
     9661 ttttctagtt gtttacggcg agattgagca cgtttggtcg ttgaagcacg aactagattg
     9721 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     9781 tcagtagcta gcttttgctc cttcaactca acaaaacgag agtaattccc cacatagcga
     9841 tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     9901 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggag
     9961 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
    10021 aggagcattt tagctagagc caaacgagta ttttgaccac cagaaagctc agcaattttc
    10081 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
    10141 taggtaaagc cacctgcttg gcgaaaattt tcagataagc ggtcataatc tgacatcagt
    10201 ttatccaaat cctcaccaga cttttcaccc atctccagct ccatctgacg cagttgttta
    10261 tctgtccgac gtaagtcatc aaagacatga agcatctcat catagatggt attttcagac
    10321 tcaaaacggc tatcttgagc taggtaagac agagaaatat cttttttctt attgatttct
    10381 ccactagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt acctgcacca
    10441 tttttcccaa caagggcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
    10501 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat catacaagta
    10561 gtatagcatg tttccctaag gcattcaaga taatcgtaag tcttttagta caacttttat
    10621 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
    10681 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagcctatta tttaattctt
    10741 ttcattattt acgtacgc
//
LOCUS       DAVLUM010000065        10685 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLUM010000065 DAVLUM010000000
VERSION     DAVLUM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10685
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.065"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            62..637
                     /locus_tag="VYN42_001658"
     CDS             62..637
                     /locus_tag="VYN42_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEV1462707.1"
                     /translation="MKTIVKICLVALSAFLLLFAGKNVFADSNSHDNLNSLEVSDRSF
                     RNGELLKSYLVKDKDRIYFDYDKAVQDKQAKDVIDMGLLVETISEDYSSNTFTPAKYF
                     KAGLPVHGNYCGPGYNGEGFTLPVVDVLDQGCQNHDRCYKWGAGIGANCECNRQLVDF
                     IKVNRRWIPESALWVADAIRVYFETIGAIGC"
     gene            631..870
                     /locus_tag="VYN42_001659"
     CDS             631..870
                     /locus_tag="VYN42_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462708.1"
                     /translation="MLNLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGKIDIFI
                     IQKILLVFGILSILMALLSKKVSLFVFGLICCLSL"
     gene            1064..3577
                     /gene="secA"
                     /locus_tag="VYN42_001660"
     CDS             1064..3577
                     /gene="secA"
                     /locus_tag="VYN42_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1462709.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKKRYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            3658..4689
                     /locus_tag="VYN42_001661"
     CDS             3658..4689
                     /locus_tag="VYN42_001661"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1462710.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYMEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            4691..5722
                     /locus_tag="VYN42_001662"
     CDS             4691..5722
                     /locus_tag="VYN42_001662"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1462711.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            5761..6129
                     /locus_tag="VYN42_001663"
     CDS             5761..6129
                     /locus_tag="VYN42_001663"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1462712.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            6119..7222
                     /locus_tag="VYN42_001664"
     CDS             6119..7222
                     /locus_tag="VYN42_001664"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1462713.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            7241..9256
                     /gene="recG"
                     /locus_tag="VYN42_001665"
     CDS             7241..9256
                     /gene="recG"
                     /locus_tag="VYN42_001665"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1462714.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLALLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            9572..10552
                     /locus_tag="VYN42_001666"
     CDS             9572..10552
                     /locus_tag="VYN42_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1462715.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT         3101 a         2056 c         2544 g         2984 t
ORIGIN      
        1 tttggtaaaa atattgtttg tgtatttagc ttataactta tgtttattag gaggagtagt
       61 catgaaaact atcgttaaaa tttgtttagt tgctttatct gcctttttac ttttatttgc
      121 tggaaaaaat gtttttgcag actctaattc acatgataac ttaaactctt tggaagttag
      181 cgatagaagt tttcgtaacg gagaattgtt gaagagttat cttgtaaaag ataaagatag
      241 gatttatttt gattatgata aagcggttca agataaacaa gcgaaagatg taattgacat
      301 gggtttattg gtagagacaa taagcgaaga ctatagttca aatacgttta cacctgctaa
      361 atattttaag gcaggattgc ctgttcacgg gaattactgt ggtcctggtt acaacgggga
      421 aggatttact ttacctgtgg tagacgtttt ggatcaaggt tgccaaaatc atgatagatg
      481 ttacaagtgg ggagctggta ttggagctaa ttgtgagtgt aatcgtcagt tagtcgattt
      541 tataaaagtt aacagacgtt ggataccaga aagtgcctta tgggttgcgg atgctatcag
      601 agtttatttt gaaacgattg gagctatagg atgttgaatc taaaatcatt tattacacgc
      661 tattctaagg tctatattgg tttagttctg ttgatctgga ttgctttctt ctttcttcct
      721 tggggcagtc cgattctggg ggggaagatt gacatcttca tcatacagaa aatcttgcta
      781 gtttttggaa ttctgtccat tttgatggcc ttgctgtcca agaaagtcag tctctttgtt
      841 tttggactga tttgctgtct ttctctttga attaacttat ttatcacatt tgccattttg
      901 ccaatttttg gcaattaaac agtcataaaa gtcggagagg ttagcttgaa aactaacctc
      961 tttttccttt tcaaaatggg gattcttcct tgaaaataat cagtaattgt gctaaaatta
     1021 aaggaacatt ctaaaatatt cggaatttaa agtaaggaaa aacatggcta atattttaaa
     1081 aacaattatc gaaaatgata aaggagaaat ccgtcgtctg gaaaagatgg ctgacaaggt
     1141 tttcaaatac gaagaccaaa tggctgcttt gactgacgac caactaaaag caaaaacagt
     1201 tgaatttaag aaacgttatc aaaatggaga atcactggat tcattgcttt acgaagcatt
     1261 tgcggttgtc cgtgaaggtg ccaaacgtgt cctaggtctc ttcccttata aggttcaggt
     1321 catggggggg attgttcttc accatggtga cgtgccagag atgcgtacag gggaagggaa
     1381 aaccttgact gcgaccatgc cggtatacct caatgccctt tcaggtaaag gggttcacgt
     1441 agttacggtt aatgaatacc tgtcagaacg tgacgcgact gagatgggtg aattgtactc
     1501 ttggcttggt ttgtcagtag ggattaactt ggctaccaaa tctccaatgg agaaaaaaga
     1561 agcctatgag tgtgatatta cttactcaac taactcagaa atcggatttg actaccttcg
     1621 tgacaacatg gtcgttcgcg ctgaaaacat ggtacaacgt ccgcttaact atgccttggt
     1681 cgatgaggtt gactctatct tgattgacga ggctcgtaca cctttgattg tatcaggtgc
     1741 caatgcggtt gaaaccagtc agttgtatca catggcagac cactatgtaa aatctttgaa
     1801 caaagatgac tacatcatcg atgtgcagtc taagactatt ggtttgtctg attcagggat
     1861 tgacagggct gaaagctact tcaaacttga aaacctctat gacatcgaaa acgtggcttt
     1921 gacccacttt atcgataacg cccttcgtgc caactacatc atgcttctcg atattgacta
     1981 tgtggtgagc gaagagcaag aaatcttgat tgtcgaccaa tttacaggtc gtaccatgga
     2041 aggtcgtcgt tattctgatg gattgcacca agctattgaa gccaaagaag gtgtgccaat
     2101 ccaggatgaa accaagacat ctgcctcaat cacgtaccaa aacctcttcc gtatgtacaa
     2161 gaaattgtct ggtatgacgg gtacaggtaa gactgaggaa gaagaattcc gtgaaatcta
     2221 caacattcgt gttattccaa tcccaacaaa ccgtcctgtt caacgtattg accactcaga
     2281 ccttctttat gcaagtatcg aatctaagtt taaagcggtt gtcgaagacg ttaaggctcg
     2341 ttaccaaaag ggtcaacctg tcttggttgg tacagtagcg gttgaaacta gtgactacat
     2401 ttctaagaaa ttggttgcag ctggtgttcc tcacgaagtc ttgaatgcca aaaaccacta
     2461 tagagaagcc caaatcatca tgaatgctgg tcaacgtggt gccgttacca tcgcaaccaa
     2521 catggcgggt cgtggtaccg acatcaagct tggtgaaggt gttcgtgaac ttggaggact
     2581 ttgtgttatt ggtacagaac gtcatgaaag tcgtcgtatc gataaccagc ttcgtggacg
     2641 ttcaggtcgt caaggagatc caggtgagtc acaattctac ctatctcttg aagatgattt
     2701 gatgaaacgt tttggttctg aacgcttgaa gggaatcttt gaacgtctca acatgtctga
     2761 agaggcgatt gagtctcgca tgttgacgcg tcaggttgaa gcagctcaga aacgtgtcga
     2821 aggaaataac tacgataccc gtaaacaagt ccttcaatac gatgatgtca tgcgtgaaca
     2881 acgtgagatt atctatgctc aacgttacga tgtcatcact gcagatcgtg acttggcacc
     2941 tgaaattcag tctatgatca aacgcacgat tgaacgtgtc gttgatggtc atgcgcgtgc
     3001 caaacaagat gaaaaactag aggcaatttt gaactttgct aagtacaact tgcttcctga
     3061 agattctatt acgatggaag acttgtcagg cttgtctgat aaggccatca aggaagagct
     3121 tttccaacgt gccttgaagg tttacgatag tcaggtttca aaactacgcg atgaagaagc
     3181 agttaaagaa ttccaaaaag ttttgattct acgagtggtg gataacaagt ggacagatca
     3241 tatcgatgcc cttgatcaat tgcgtaacgc ggttggactt cgtggctatg ctcagaacaa
     3301 ccctgttgtt gagtatcagg cagaaggttt ccgtatgttt aatgatatga ttggttcgat
     3361 tgagtttgat gtgacacgct tgatgatgaa agcacaaatt catgaacaag aaagaccaca
     3421 ggcagaacgt catatcagta caacagcgac tcgcaatatc gctgctcacc aagcaagtat
     3481 gccagaagat ttggatttga gccagattgg acgcaatgaa ctttgcccat gtggttctgg
     3541 taagaaattt aaaaactgtc acggtaaaag acaataaaat gagatagttt agaggcggat
     3601 atcttgtgaa aagtaaattt ttactgggta tccgtttgct ttataaggag atgagttatg
     3661 gtatttacag caaaaagctc taaaataaat atagaagaag ttcgtgcctt gtcaaaatta
     3721 gaaggtcagg ctttggagag gaaatcacag cgagatcaag agctagaagc cattatacgt
     3781 ggagaagacc agcgaattct cttggtaatc gggccatgct catctgacaa cgaagaagct
     3841 gtccttgaat acgctaagcg tttggcagtc ctacaagaag aagtggcaga tcgtatcttt
     3901 atggttatgc gtgtttatac tgccaaaccc cgtaccaacg gagatggcta taagggcttg
     3961 attcaccagc ctaacgcgac agaagcgcct agtcttatca atggaatcaa agccgttcgc
     4021 catcttcact atcgtgtcat cacagaaaca gggatgacaa ctgctgatga aatgctttat
     4081 cctgaaaacc ttccgcttgt agatgatttg atttcttaca tggcagttgg tgcccgttca
     4141 gttgaagacc agcaacaccg ctttgtggca agtggggcag gattttctac tggttttaaa
     4201 aatccaacct ctggaaatct caatgtcatg tttaatggga tttatgctgc tcaaaacaaa
     4261 caaagtttcc ttttcttagg aaaagaagta gaaacaactg ggaacccgct ttcacacgct
     4321 attcttcgtg gtgctcttaa tgagtatgga aaaaatattc ccaactacta ttatgacaat
     4381 ttaattgata ccattgccca gtatgagaaa atgggcttgg aaaatccttt tatcatcatt
     4441 gataccaatc atgacaattc tggtaagcag tatatggaac agatccgaat tgtccgccag
     4501 accttgatta accgtgcttg gaatgaaaaa attaagcagt tcgttcgtgg ttttatgatt
     4561 gagtcttatc tggaagatgg tcgacaaaat gagccagaag tatttggtaa gtctatcaca
     4621 gacccttgcc tgggttggga taacacagaa gctcttgtca gagaaattta caaaacgtta
     4681 ggagaataag atggcattta ttgaaaaagg tcaagaaatc gatatggaag tcatcaaggc
     4741 tgaaacccaa ttgtctgcag aagccttgag actcaaggaa agccgtgaca gggaattggc
     4801 agatattatt tcaggggaag atgaccgtat tctcttggtg attggtcctt gctcttctga
     4861 taatgaagag gcggtcttgg aatatgctcg ccgtttatcc gccttgcaaa agaaggtagc
     4921 ggacaagatt ttcatggtca tgcgcgtgta tactgctaag cctcgtacca atggagacgg
     4981 ctataaagga ttggttcacc agccagatac ttctaaggct ccaagcctga ttaacggctt
     5041 gcaggctgtg cgccagttgc actaccgcgt gattacagag actggtttga caacggcaga
     5101 tgagatgctt tatccgtcaa atctgatctt ggtggatgac ttggtcagct accatgccgt
     5161 tggagctcgt tctgtggaag accaagagca ccgctttgtg gcttctggga ttgatgcacc
     5221 agtagggatg aaaaatccaa cctcaggaaa tttgggtgtt atgtttaacg ccatctatgc
     5281 tgctcaaaac aagcaaacct tcctttatca tgggcaggaa gttgagacat caggtaatcc
     5341 tttggcccat gttatcctcc gtggagcagt caacgagtat ggcaattata tgccgaatta
     5401 ctactatgaa aacctactcc aagccattga acgctatgaa accatgggac ttgaaaatcc
     5461 ttttatcctc attgacacca accatgataa ctcaggcaag caatatatgg agcagattcg
     5521 aattgttcgc cagacattgc agaatcgtga ttggaatgag aaaattaaaa agacggttcg
     5581 aggatttatg attgaatctt acctagcaga tggtcgtcaa aaccaaccag agatctttgg
     5641 ttgctctatt actgaccctt gcctaggttg ggaaaataca gaggccttgg tagaagagat
     5701 ttatgttacc ttgacaaaat aagtgaaaag gatggagttg gggaatctca actccttttg
     5761 atgagaatga tagttggaca cggaattgac atcgaagaat tggcttcgat agaaagcgca
     5821 gttacacgac atgaaggatt tgctaagcgt gtactgaccg ctcaggaaat ggagcgcttc
     5881 accagtctca aaggacgcag gcaaatagaa tatttagctg gtcgctggtc ggctaaggag
     5941 gccttttcca aggctatggg aacgggcatt agcaagctcg gttttcagga tttggaagtc
     6001 ttgaacaatg aacgtggggc gccttatttt agtcaggcac cattttcagg aaagatttgg
     6061 ctgtctatca gccacaccga tcagtttgtg acagccagtg tcattttgga ggaaaatcat
     6121 gaaagctagt ccacatagac caaccaaggc tctgattcat ctgggagcta ttcgacaaaa
     6181 tattcagcaa atgggggctc atatccctca aggaacgctc aagttggctg tggtcaaggc
     6241 caatgcttat ggtcatggag ctgttgccgt tgccaaggca attcaagatg atgttgatgg
     6301 tttttgcgtt tccaatatcg atgaagccat tgaactcaga caagctggac tcagcaagcc
     6361 aatcctcatt ttaggagttt ctgaaatcga agctgttgct ctagctaaag aatatgactt
     6421 caccttgaca gtggctggac tggagtggat tcaagcactc ttagataagg aagtggacct
     6481 aactggattg acagtccacc tcaagattga ttcagggatg ggacggattg gttttagaga
     6541 ggccagtgag gttgagcagg ctcaagattt gctacaacaa cacggtgttc gtgttgaagg
     6601 aatctttacc cactttgcta ctgctgatga ggaatcagat gactatttta atgcccagtt
     6661 agaacggttt aaaactattt tagctagtat gaaggaagtt ccagagctgg ttcatgctag
     6721 caattctgca acgactcttt ggcatgtaga gactattttc aatgcggttc gtatgggaga
     6781 tgccatgtat ggcctcaatc caagtggagc ggtcttggat ttgccttatg atttgatacc
     6841 ggccttgacc ttggagtctg ctctggttca tgtcaagaca gttccagctg gagcttgcat
     6901 gggctatgga gcaacttatc aagcggatag cgagcaagtc atcgcgaccg tgccaatcgg
     6961 gtatgcagat ggatggacaa gagacatgca aaatttctct gtcttggtag atggccaagc
     7021 ttgcccaatt gtcggcaggg tttcgatgga ccaaatcact attcgattgc ctaagcttta
     7081 tccgctagga accaaggtaa ccttgattgg ctccaatggg gataaggaaa tcactgcaac
     7141 tcaggtagcg acctaccgcg tcaccattaa ctatgaggtg gtttgcctcc tcagcgaccg
     7201 tattccgaga gaatattatt agaaaagaaa ggagtggagc atgaatctac atcaaccctt
     7261 gcatgtcttg cctggtgtgg gaccaaagtc agcagaaaaa tacgccaaac taggaattga
     7321 aaacttgcaa gatctcttgc tctactttcc tttccgttat gaagacttca aaaccaagca
     7381 ggtgctggaa ctagaagacg gtgagaaggc agttctttct ggtcaggtag tgactcctgc
     7441 tagtgtccag tattatggtt tcaagcgcaa tcgcctgcgt tttagtctca agcagggaga
     7501 ggtcgttttt gcggtgaatt tctttaacca gccctatctg gctgataaaa tagagttggg
     7561 agcaactctt gctgtctttg gaaaatggga ccgcgctaag gctagtctga ctgggatgaa
     7621 ggttctggct caggtagaag atgacctcca gcctgtctat cgtctggctc agggaatcag
     7681 tcaggccagt ctggttaagg tcatcaagac ggcttttgat cagggactag ccctcttgat
     7741 agaagaaaat ctgccccagt ctttactaga caaatacaaa ctcatgtccc gttgtcaggc
     7801 agtccgagct atgcattttc caaaggattt ggcagaatac aagcaggctc ttcgccgtat
     7861 aaagtttgag gaactctttt atttccaaat gcagctgcag atgctcaagt ctgaaaatag
     7921 agttcaggga agtggtctgg ttctgaattg gtctcaggaa aaagtgacag cagttaaagt
     7981 aagtcttcct tttgccctga cccaagctca ggaaaagagt ttgcaggaaa ttttaactga
     8041 tatgaagtcc gaccaccaca tgaatcgtct cctacaaggg gatgtgggga gtggaaaaac
     8101 ggtagtcgct ggcttggcca tgtttgcggc agtgacagca ggttatcagg ctgccctaat
     8161 ggtaccaaca gaaatcctcg cagagcaaca ctttgagagt ttacagaacc tttttcccaa
     8221 tttgaaactg gctctcttga caggttcctt gaaagctgca gaaaagagag aggtcttgga
     8281 gaccattgcc aagggtgagg ctgatttgat tatcggaact cacgctctga tacaagatgg
     8341 ggtggagtat gctcgtcttg gtttgattat tatcgatgag cagcaccgtt ttggtgtagg
     8401 gcaaaggcgt attttacggg aaaaaggtga caatccagat gtcctcatga tgacggcgac
     8461 tcccattcca cggacgcttg ccatcacagc ctttggagat atggatgttt ccattatcga
     8521 ccagatgcca gcaggtcgga agcctattgt gacgcgctgg atcaaacatg agcaactacc
     8581 tcaggtcttg acttggttag agggggaaat tcaaaaaggt tcccaagcct atgtcatctc
     8641 tcctttgatt gaagaatcag aagctctaga tttgaaaaat gccattgcct tatcagagga
     8701 gttgacgact cattttgcag gcaaggcaga ggtggctctt ctacatggta ggatgaagag
     8761 tgacgaaaaa gaccagatca tgcaggattt caaggagaga aagacggata ttctggtttc
     8821 gacgacggtt attgaggttg gggtcaacgt tcccaatgcg actgtcatga ttatcatgga
     8881 tgccgatcgc ttcggtctca gtcaacttca ccagcttaga ggtcgtgtcg gtcgggggga
     8941 caagcagtcc tacgctgttc tcgttgccaa tcccaagacg gattctggga aagaccgcat
     9001 gcgcatcatg acagaaacga ccaatggatt tgtccttgcg gaggaagatt tgaaaatgcg
     9061 tggttctggt gagatttttg gaaccagaca gtcaggactt ccagagttcc aagtggctga
     9121 tattatcgaa gattttccga ttttagaaga agcaagaaag gttgctagct acattagttc
     9181 tatagaagct tggcaagaag atccagagtg gcgcatgatt gcccttcatc tggaaaagaa
     9241 agaacatctg gattaagctt tctctaagga aaacttaagc tagtttttag gtttggctct
     9301 tatactaaag tcatcaaaaa gaaacgagga ctctcatatg acagtaacga ttaaagtaaa
     9361 ttaccaaacc actttccaaa agaaggaagc aaaaaactag tataaacaga agagagagcg
     9421 aaatgctctt tttcgtttct aaaactactt tcagcccatc atcctaaaag taaagaatct
     9481 aaattcactt tctatttatc cttctttctt gcattgatta catagatatg ctacagttgt
     9541 ggtaacgatt acaaaataaa aggagcatgc tatgaaaaat ccagctttgc tagaagaaat
     9601 taagacctat agaggaaggg atgaggttcc ggaagacttt gatgctttct gggatgggga
     9661 agtgaaaaat gtttccacgc ttccatccta ccacttggag gaaagagatt tccacattcc
     9721 tcaagtcaag tgctatgagt taacatttga aggaagcaag gaaggaaagg tctatgcacg
     9781 cattgttctt ccaaagagtg aggagaaggt tccactaatc ttccattttc atggttatat
     9841 gggacgtggc tgggactggg ccgacatgct gggcttcacc gtagctggtt acggtgttgt
     9901 ttccatggat gtgcggggtc agtcaggtta ctcacaagac ggcttgcgtt ctcctttagg
     9961 aaataccgtg aaggggcata ttatccgtgg tgctgtggaa ggtcgggacc acctctttta
    10021 taaggatgtt tatctggata tttaccagtt ggtcgaaatt gttgctagtc tgtctcaggt
    10081 tgatgagaag cgtctttcta gctatggtgc ctcacaagga ggggctctag ctctagttgc
    10141 agcagcgctc aatcctcgaa ttcagaaaac agttgccatt tatcccttct tgtcagactt
    10201 cagacgggtg attgagattg gtaatactag cgaggcttac gacgaacttt tccgttattt
    10261 caagtttcac gaccccttcc atgaaacaga ggaggaaatc atggcgaccc ttgcctatat
    10321 cgatgtcaaa aatcttgccc atcgtatcca aggtgaggtt aagatgatta cgggcttgga
    10381 cgacgatgtt tgctatccca ttacccagtt tgcgatttat aatcgtctga cctgcgataa
    10441 aacctatcgc atcatgcctg agtatgctca cgaagccatg aatgtatttg tcaatgacca
    10501 agtctacaac tggctctgtg gaagtgagat tccttttaaa tatctaaaat aaggagtcga
    10561 ctctaagcac aaaatcttaa aaattacaaa cacgcatagt atcaggggat taaaaaaact
    10621 tgatactatg cgttttatca tggaaatata gtaaaatgaa acaagaatag gacaaaacga
    10681 tcagg
//
LOCUS       DAVLUM010000066        10651 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLUM010000066 DAVLUM010000000
VERSION     DAVLUM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.066"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(7..1221)
                     /locus_tag="VYN42_001667"
     CDS             complement(7..1221)
                     /locus_tag="VYN42_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1462716.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1659)
                     /locus_tag="VYN42_001668"
                     /pseudo
     CDS             complement(1377..1659)
                     /locus_tag="VYN42_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1730..2182
                     /locus_tag="VYN42_001669"
     CDS             1730..2182
                     /locus_tag="VYN42_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1462717.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2217..3605)
                     /locus_tag="VYN42_001670"
     CDS             complement(2217..3605)
                     /locus_tag="VYN42_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1462718.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3671..4633
                     /locus_tag="VYN42_001671"
     CDS             3671..4633
                     /locus_tag="VYN42_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1462719.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLIVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAKKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4929..5939)
                     /gene="ccpA"
                     /locus_tag="VYN42_001672"
     CDS             complement(4929..5939)
                     /gene="ccpA"
                     /locus_tag="VYN42_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1462720.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6364..6963)
                     /locus_tag="VYN42_001673"
     CDS             complement(6364..6963)
                     /locus_tag="VYN42_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1462721.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(6965..8062)
                     /locus_tag="VYN42_001674"
     CDS             complement(6965..8062)
                     /locus_tag="VYN42_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1462722.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(8062..8799)
                     /locus_tag="VYN42_001675"
     CDS             complement(8062..8799)
                     /locus_tag="VYN42_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1462723.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8801..9685)
                     /locus_tag="VYN42_001676"
     CDS             complement(8801..9685)
                     /locus_tag="VYN42_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462724.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9672..9866)
                     /locus_tag="VYN42_001677"
     CDS             complement(9672..9866)
                     /locus_tag="VYN42_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462725.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(9863..10069)
                     /locus_tag="VYN42_001678"
     CDS             complement(9863..10069)
                     /locus_tag="VYN42_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462726.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         3274 a         2414 c         1918 g         3045 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacgattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattcaacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggt attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaaagcaa gcctagaaag gagtcataaa gaagattaaa
     1441 catgaggaaa agcccccata tcatcaagta atcccaacgc ccacttcgtt ttacaactag
     1501 aaataagatt agatggtaga gtacatgaaa gactaaaaat ccaataaaac ttggataaag
     1561 aagcggtacc agactctcta attgccagat catgatcact tctaccaaga ctgaaactag
     1621 gataattcca taataaagga aatttgattt ttgaaaaata ctttttttgc tttacttcta
     1681 tagtgaaaag gtttacaatt atagtaagaa aatttcagga ggtttcatta tggcacaacg
     1741 ttaccaaaat atcatggtcg caatcgatgg ttctaaggaa gcggacttgg cttttgtcaa
     1801 gggagttcat tctgctctac gaaacgacgc taaactcacc atcgcacatg tcattgacac
     1861 acgcgctctc caaagcgtat ccacctttga tgctgaagtt tacgaagaac tccaagtcga
     1921 cgctgaaagt ctgatgaaag agtacgaaaa acgtgctaaa gatgctgggg tagcagatgt
     1981 tcatatcgtc attgaaatgg gaaatccaaa gaccctgcta gcacgtacta ttccagatgc
     2041 cgaggaagtg gacctcatcc tcgttggcgc aactggtctc aacgcctttg aacgcctctt
     2101 ggtcggctct tcatctgaat acatactccg ccatgctaag gtcgatttgc tggttgtgag
     2161 agaacaagaa aaaaccttat aatcacaaag aaaaggagcc cctagctcct ttttgtttac
     2221 gatttatttc tctctttatg gcgttcgtaa gccttgagct ggcgctgcag ttccttttta
     2281 atagcaggtt ctggagcata tttttcttcc caattatctg gttttaagat tttatgggtc
     2341 actggatcaa aatgagcctt gccatctgga aaaattttcc ccatattggc ctgatggaca
     2401 atatcaaaaa tacgttctgg gtccaccccc atcaagacaa aactgccgta ggtgaagtaa
     2461 agcgtgtcaa tcaaggcatc cacttgccct atcaaatctt gctgagcagg tgtcttcttg
     2521 gctactttac ctgctgcctt atcaagggcc tgatgaagtt gcgatacagc ttgaccaaaa
     2581 tcttcttcag aaggactggc tgctcgaaca aactccacca attcttctat tttaaaacca
     2641 gccctatggg ttgcaccctc taaatcccaa gctcgaggtt cttcttgggt tcgttcatcc
     2701 atcatgtggt ggaaggtctt gaccttattg aaatgatagt cacggctgac aaagactttt
     2761 tctgaagaca aaacaccaaa atgttccaag gccttgtgga tcccatcttg ttgattgcta
     2821 gtggtaatgt gcttggcagc ttccttgaca ctgctactac catttcccat agcgaccgac
     2881 ataccgacgc cagccagcat ttcaaggtca ttatctgagt caccaaaagc catgacttgg
     2941 ttgaggtcaa agccatattc tttcccaact cggcgaatac cttctaattt agaatttccc
     3001 tgattgatga catccgatgc aaaaggattg ctacgtgtca atttcaagtc ttcaaaatca
     3061 gctgccgcct tctcagattc ttctggtgtc atcagcatca aaacttggta gataggctga
     3121 ttcatcaggt gaagcaggtc ctcttccttt tggggaacaa ccttgctgac catgcgatta
     3181 aaagactgac tcaccgtccg agttaaaaca gagggaacga agcgactaat tcgttgggaa
     3241 aaagaaccca gaccaaagga catgatttta gaacccaaca tggcatcctt ggtccctaga
     3301 gcaatctccg tgccctcttt tttagcatag ctaattagat ggcgcaaatg taacttggaa
     3361 atagggctcg tgaacaagac tctgtcttta ctaaagatat actggccatt ataggttacc
     3421 gcaaaatcca gatccaaatc gtccatcaat tccttaacaa aaaaaggtcc tcgccctgtc
     3481 gctacgccaa ctagtacccc ttgttctttg acaatcttaa tcgcgtcctt agtggatttc
     3541 aaaacactct tgcgattgtt gaccaaggtt ccatcgatat caaaaaaaac agctttgact
     3601 tccatcctat tccaatctcc ccttttgtga tacaatgatt ataccacatt tcagaaagag
     3661 ttagtaaatc atgcctaaga aaatccttgt tttacatacg ggtggaacta tttccatgca
     3721 ggccgatgct tctggcgctg ttgtgacgag ttcagataat cccatgaacc atgtgtccaa
     3781 cccacttgaa ggaatccaag tccacgcctt ggactttttt aaccttccaa gtccccatat
     3841 caaacccaaa catatgctgg tcctctacca gaaaattaaa gaggaagcag ataactacga
     3901 tggagtggtg atcacacacg gaaccgatac tttagaggaa acagcctatt tccttgatac
     3961 catggaagtt ccccatatgc ctatcgttct aacaggagcc atgcgtagct ccaatgaact
     4021 cggtagtgat ggtgtttata attacctaag tgctttacga gtggccagcg atgacagggc
     4081 tgctgacaaa ggagttttga tcgttatgaa cgatgaaatc cacgctgcca agtatgtcac
     4141 caaaacacat acgactaatg tcagcacctt ccagactcca acacatggcc ccctcggtct
     4201 catcatgaaa caggaaatcc tctacttcaa aacagctgaa cctcgtgttc gctttgacct
     4261 tgatcacata caaggtttag tccctatcat ctcggcttat gctggtatga cagatgagct
     4321 gattgatatg ctggatttag aacacttgga cggtttgatt atccaagcct tcggagctgg
     4381 taatattccc aaagaaacgg ctaaaaaatt agaaagcctt ctgcaaaaag gaatcccagt
     4441 cgctctggta tcacgatgct ttaacggtat tgccgagcct gtttatgcct accagggtgg
     4501 gggcgtacag ttgcaaaaag caggcgtttt ctttgttaaa gaactcaacg cccaaaaagc
     4561 ccgcttgaaa ctcctcatcg ccctcaatgc cggactaaca ggacaggctt tgaaagacta
     4621 tatggaaggc taatactctt cgaaaatctc tgcaaaccac gtcacgtcgc cttaccgtat
     4681 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaacatgttt tgagctgact
     4741 tcgtcagttc tatctgcaac ctcaaagcag tgcttttagc tgacttcgtc agttctatct
     4801 acaacctcaa aacagtgtgt tgcgcagcct ttaaccagcc gcctagtccg ctctatggta
     4861 ttcattaagt caacatctct tgtttaagag cacaaaatca ggaaatcttc tcgattccct
     4921 gattttttct atttacgttt tcgtgttgag ctacgttctg tcaaaccatg aggtaagaga
     4981 acttcacgtt cttccaactc ttccttatgc ataatcttgg tcaacatacg catactaatg
     5041 gcaccaaggt cataaagagg ttgggcaatc gttgtcaagt ttggacgggt aaagcgtgag
     5101 atttgtgaat catcactagt aataatttca aaatcttctg gcacagaaac acccttatca
     5161 gccaaaccgt tcaagactcc tgctgccaac tcatcacctg tcacaactgc tgcagttgca
     5221 tttgatgaaa tcaaacgctc tgctaaggcg taaccatcat catagctata tttagattca
     5281 aataccaaac cctcactata agtgattcct gcttttttca aggtttcctt gtagccaact
     5341 aaacgaacct taccattgat gtcatccact agcggaccgc taacgaaagc aatacgctca
     5401 ttttctttag caaggtaact cactgcatca attgttgctt gcttatagtc aatattgaca
     5461 ctgggcaact ggtgctcaac atcgacagtt cctgcgagaa caatcggagt acgtgaacgc
     5521 gaaaattctg agcgaatttt atctgtcaag tgataaccca tatagataat gccatctacc
     5581 tgctttgaaa agagggtatt gacaacagaa acttctttct cgttatcttc atcgctatta
     5641 gctaggacaa tattgtactt gtacatttct gcaatatcat caatcccctt agccaaactc
     5701 gaaaaataac cattggtaat atttggaatc acgacaccga cagtggttgt ctttttactt
     5761 gcaagaccac gcgcaactgc atttggacga taatccaaac gatcaattac ctctagcact
     5821 tttttacggg tattctcttt tacattttta ttgccattga ccacacggct gaccgtcgcc
     5881 atggaaacac ctgcttcacg agcgacatca taaatggtta ctgtatcatc tgcattcatt
     5941 ccttttcctg tcctttctat ctcacacatt cttttacaag tagaggtact gattgaagct
     6001 ctatatctac ttacaaaagt gaagatgtga aaatttcgtt ttcatatttc tacttattcc
     6061 attctatcac taattgtaaa cactttcaag tgttttttga agattgattg aaaaaatttc
     6121 atagaaaacc taggtttagc tccttgctac caccttagac taaacaaaaa ggaggaaact
     6181 aagccctcct aaagttatag taaaatgaaa taagaacagg ataaatcgat caggacagtc
     6241 aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta
     6301 taggtattgt tccattcaat cccatcaatt ttagcacata atggttttcg agatatgata
     6361 gtattacaac caaccagatt cttttgcgat attagctgcc tctgttcgat tacctgcatc
     6421 tagtttcgaa agaatattag tgacatagtt tcgaatagtt ccgtttgaga ggtaaagctg
     6481 atctgcgatt tcttggttgg ataagccccg ggcaattccc tttaagacag caatctcttg
     6541 ttctgtcaac ggattgggac gggtcatcac cacttccatc aattcaggtg aatactcctt
     6601 gcgtccttcg aggacggtgt gcaaggtttg catgaggtct gcaatgcttc gttcctttaa
     6661 tacataagca tccactccag ccttgaccgc acgttcaaaa tacccagcac gcttgaaggt
     6721 cgtcaccaca accacctttg tttcaagcct ttctgatcgt atccactcca agacttcaag
     6781 acctgtctta acaggcattt ctacgtcaag gatggcgata tctacagact ccttttctaa
     6841 tagttggatt gcttcttgcc cattcttggc ttgaaggaca gactccacat ctggttgaag
     6901 cgtgagcaat tgacacatgg catctcgcaa catactttga tcttctgcga ctaatacttt
     6961 catcttagtt tctctcctta taaggtagtc gaacttgcac ttccgttgga tgtttctgac
     7021 tgattacact tacttctcct gaaaatggaa aaacacgatc tcggactgta tggagctcat
     7081 ctccttttag aaaagcaaag ccgcagccat catcacttac tgttaaaatg agttccttct
     7141 ctgtccgttc taattttaag taagctttag acgctttggc atgtttgatg atattggtca
     7201 ccaactcaag caaaatcata gaagccattg aatccaattc ttgagtaagg ctagcagtat
     7261 ctagttggtt atctgtttcc acctcaattc cagcaatttc taacatcttt ttcacagtct
     7321 ctagttcgga tgtcaaagtt ctagacttaa gattttccac aatggttcga acttcacaca
     7381 ttgattcttt gctaatttgc tgtatttctc ttaattcctt ttccacttgt ggataagcct
     7441 gcatttgaaa tagctgcaag gctagatctg tcttgacact aagcatagca aaggtatgtc
     7501 ccagactatc atgcaaatcc tgaccgatac gattgcgctc attttctgct agcaatagat
     7561 ttatctgggt attttgctcg acctgagctt ctttcaaatc ctcgacaagg cgaattcgaa
     7621 ccgagcccaa agtcatcaaa tcgacaaaag taagaattac aagcatatag actagaaact
     7681 caacttcgat tctctgaaaa atcaaaagtc gccccacaac aaggacttga gcaaggagaa
     7741 atgtccatac atgtaaagac tttaaactac gtacgccaaa atgataaatt aagagattgg
     7801 aaaggaaaaa gaaaaaccag atataattcc cagcaacaaa ggcggtattc ccagctacat
     7861 agaccagcat gatcccccag aaaagccaag ataggcgctg gttcttagtt attaaaacac
     7921 ccaaatacgt cactacaaat agaatatcaa ccaataaatg ccaagcagga agctccccaa
     7981 tcactacagg taggatggga aaaagcataa aaatcaaact ggcccaaaac atatagtgta
     8041 tgcttttcag tctttcaagc attaagcatt ctccttatga ccttgaaggt aaatagtcaa
     8101 accaaataaa actgctgaaa aaacaagtaa ataaactgtg gctgatagat tgatgccacc
     8161 ctcgtttaag aaggtcttga gcaactccat caattgatag gtcgggagac acttaccaac
     8221 tgcttgcatc cagtctggaa ataaagaaat gggcatccag agtccgccta aaacagccaa
     8281 tcctagataa agaagattgc ccacaacaga catcagctga ctagttggta agagagtcaa
     8341 ggtcaagcca agtgctacaa aagcaatact ccccacaatc agcaaaatcg cagctccaac
     8401 ccattttact agaggcatgt ctacacctct tacaaaatgt ccaactgaga aaaccaccaa
     8461 gattgaaacc aaataatcaa ccagcatact tgttatcttt gatagataat attctaccat
     8521 atttacaggg ctatgacgca atgttttctg ccagttattc atcttatcgg tatgtaaaac
     8581 agctggaaat gagaggatag ttgtcgacat catggaaaag gcagtcatgg agatgaggta
     8641 atcacgcata aaattcgcgg gttcacctgg tgtgtcctga tagataccag aaaaaaataa
     8701 atagaaagcc gtcggcatcc ctaccgacaa tagataatag attaattgtc gtttggtcaa
     8761 taaaaattct atcttactaa gtgctatcca tcgtttcatc ttagttatct cccttctgcg
     8821 tctcttcaaa gattgtattc aacaaactac gattattaac ttcgatttct tgcatcctac
     8881 atcctgcttg ggctaatagt tcccagaaag catctgcttc tcgagtgact acttgtaaag
     8941 aatcttgctt tagggtccag ttttcaacca aatttgactg ctctacgact tccttgtaag
     9001 ctataggaag gataaagtgc ttttctattt cctcgctacg catagctaga ggcgtcgtat
     9061 ctcgaatcaa ctctccctta tttaagagca aaatgcggtc tgcagtgtgt tccacttcct
     9121 caatataatg ggacgaatag agaatggtga ctccttgcgc ttttaactcc tggacaattt
     9181 cccaaaaacg ttgacgagtt gaggtatcca tggacgcagt aggctcatct aaaaaaacaa
     9241 tctttggtcg cccaattaag gtcaagacga aagaaaagag acgcttttga ccgcctgata
     9301 atttttctgc caactgttct ttttgttgct tgacaaactg caatagttga tcaatttcct
     9361 gattgctcaa aggatttgga tagatacgtt gaaagaaagc aatcaactct ttaactttta
     9421 atttctgaac gattacattt tcttgaggga ggtaagccct agtatagtct aacttagaac
     9481 tcgtcactgg taaaccttga atagatactt gaccgcttgt gaccagttta tctccaagca
     9541 aacaatctaa gagtgttgtc tttccggcac catttggacc aattaaggca acacattcac
     9601 catcgttgat ttcaaaggag atgttccgca aaatttcctt gtcttttatt ttcttactca
     9661 atttttcaac tttaaccaca gtcatgagac tctcctttca accactccat tcccataggg
     9721 aaaacgacga aaatcataaa tccaaacccc aaagcaccat gaatgaattg gcgaagcaag
     9781 gcttgatcaa accaatcagt aaacatttcc actaaccata ccaagagtga caggccgata
     9841 aagaaataga tgatccctct cttcattctt caaactcctt tttcacatct ctgactaatt
     9901 tcaaaccttc tctaacaagc caagacatga ttccaaagcc agcaaagacc ttccaaggaa
     9961 aatggtagaa atcctcatcc aatcccgaaa acatgagata ggtcataact cctgctacta
    10021 ctaaactcat tgcaataatc attttatttc tcatctcttc ttcccccatt tcatactaca
    10081 attatagtct tttaaaatca gaggaggtag aagcttctgt cactagaaaa tatgacaaat
    10141 gtcataaaaa attctgttca aaacaagcaa gatacactat acaataaaac acaatcagaa
    10201 aaatctaagg caacttcctc aaaagagata tcaaactcaa ttcacaccac aatgtaaact
    10261 aatacttatt taaaatcaaa aagagtagaa atttttatca gacaaataca tatatagtgt
    10321 attgaatcta taacagtagg ccttaaatac taaaatattt ctataaatta atttaacttt
    10381 cctgatagag ctgttcatat cttatttcaa ttctctatat tatacgttga acaaaaccct
    10441 tctattgctt tcttaaaaat ttataagagt tataaaatct gttaaatttc aatgtgtata
    10501 cctaaactac ggtatttatt gaaaagactg gagacaaaaa gtatacgctg ccaaaatgaa
    10561 ttactgaaaa tcaaaaaaga gagaaccaaa ctgattccct cttaatgtat ataatatcta
    10621 gttttaaaaa tacacactca catatctctg t
//
LOCUS       DAVLUM010000067        10506 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLUM010000067 DAVLUM010000000
VERSION     DAVLUM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.067"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..419
                     /locus_tag="VYN42_001679"
     CDS             <1..419
                     /locus_tag="VYN42_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1462727.1"
                     /translation="YREYGRSLKGQLIRGKVSGRRYQRISLVAGLTNGELIVPMTYEE
                     TMTSDFFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPE
                     YNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            319..765
                     /locus_tag="VYN42_001680"
     CDS             319..765
                     /locus_tag="VYN42_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1462728.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPALVSIDYINCLSETTD
                     KNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKKPIPKHLPPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAINVLDKVMKKIF"
     gene            complement(903..2207)
                     /gene="eno"
                     /locus_tag="VYN42_001681"
     CDS             complement(903..2207)
                     /gene="eno"
                     /locus_tag="VYN42_001681"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1462729.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2371..2817
                     /locus_tag="VYN42_001682"
     CDS             2371..2817
                     /locus_tag="VYN42_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1462730.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2814..3929)
                     /locus_tag="VYN42_001683"
     CDS             complement(2814..3929)
                     /locus_tag="VYN42_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1462731.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVANLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3938..4171)
                     /locus_tag="VYN42_001684"
     CDS             complement(3938..4171)
                     /locus_tag="VYN42_001684"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV1462732.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCAKEVLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            complement(4212..4583)
                     /locus_tag="VYN42_001685"
     CDS             complement(4212..4583)
                     /locus_tag="VYN42_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1462733.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQLA"
     gene            complement(4642..6075)
                     /gene="glgA"
                     /locus_tag="VYN42_001686"
     CDS             complement(4642..6075)
                     /gene="glgA"
                     /locus_tag="VYN42_001686"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1462734.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6072..7211)
                     /gene="glgD"
                     /locus_tag="VYN42_001687"
     CDS             complement(6072..7211)
                     /gene="glgD"
                     /locus_tag="VYN42_001687"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1462735.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEHGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7201..8343)
                     /locus_tag="VYN42_001688"
     CDS             complement(7201..8343)
                     /locus_tag="VYN42_001688"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1462736.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8333..10261)
                     /gene="glgB"
                     /locus_tag="VYN42_001689"
     CDS             complement(8333..10261)
                     /gene="glgB"
                     /locus_tag="VYN42_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1462737.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSHLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3194 a         2303 c         1864 g         3145 t
ORIGIN      
        1 tttatcgaga atatggtcgc tcattaaaag gtcagttaat aagaggtaaa gtatctggaa
       61 gaagatatca gaggatttct ttggttgcag gtctaacaaa tggtgagtta atcgttccaa
      121 tgacttacga agagacgatg acgagcgact tttttgaagc ttggtttcag aagtttctct
      181 taccaacatt aaccacacca tcggttatta ttatggataa tgcaagattc catagaatgg
      241 gtaagttaga acttttatgc gaggagtttg gtcataaact tttacctctt cctccctact
      301 cgcctgagta caatcctatt gagaaaacat gggctcatat caaaaagcac ctcaaaaagg
      361 tattaccaag ttgcaatacc ttttacgagg ctcttttgtc ctgctcttgt ttcaattgac
      421 tatataaatt gtctaagcga aacaaccgat aagaattggc acaaaagcga ccgtattttt
      481 gttaccaata taggaaaacc agttcatagt tctatcttga gcaagtctct ccagcgagca
      541 aacgaacgcc ttaaaaaacc aattcccaaa catctgcccc ctcacatctt cagacacacc
      601 actattagca tcttatcaga aaataaaatt cctttaaaaa caatcacgga cagggttggt
      661 cattccgact ctgaagtcac tacttccatc tacacccagg tcacaaagaa tatgaaagat
      721 gaagcaatca atgtactgga taaagttatg aaaaagattt tttaaaaagt tttgtccctt
      781 ttttgtcctc taaatacaaa aatagccctt cggataaaat ccgaggggct agaaacgttg
      841 ttaaatcaac ggccgaactt ttgaatttca tggttcggga taaaatagtt cactgaacta
      901 ttttattttt taaggttgta gaatgatttc aatccacgat attcagctac ttcaccaagt
      961 tggtcttcga tacgaagcaa ttggttgtat ttagcgatgc ggtctgtacg tgaaagtgaa
     1021 ccagtcttga tttgtcctgc gttagttgca actgcaatat cagcgattgt tgaatcttca
     1081 gtttcacctg aacggtgtga tacaacagca gtgtaaccag cttctttagc catttcgata
     1141 gcttcaaaag tttcagtaag agtaccgatt tggttaactt tgataaggat tgagttagca
     1201 gcaccttctt ggataccacg tgcaaggtag tcagtgtttg ttacgaagaa gtcgtcacca
     1261 acaagttgta ctttcttacc aagacgttca gtaagagctt tccaaccatc ccagtcgttt
     1321 tcatccatac catcttcaat agtgatgatt gggtatttgt taaccaattc ttcaaggtag
     1381 tcgatttgtt ctgcagatgt acgaacagca gcaccttcac cttcaaattt agtgtagtcg
     1441 taaactttac gttctttatc gtagaattct gatgaagcac agtcaaatcc gataaatacg
     1501 tctttacctg gtacatatcc agcagcttca atcgcagcaa ggatagtttc aacaccatct
     1561 tcagttcctt cgaaacgagg agcgaatcca ccttcgtcac ctacggcagt ttccaaacca
     1621 cgtgatttaa ggattttctt aagagcgtgg aagatttcag caccgtaacg aagggcttct
     1681 ttaaatgttg gcgcaccaac tggcaagatc atgaactctt ggaaagcgat tggagcgtca
     1741 gagtgagaac caccgttgat gatgttcatc attggagttg gaagaacttt agtgttgaat
     1801 ccaccaagat agctgtaaag tgggatttca aggtagtcag cagcagcacg agctacagcg
     1861 atagacacac cgaggattgc attcgcaccc aatttacctt tgttaggagt accgtcaagt
     1921 gcgatcatag cacggtcaat agcttgttga tcacgtacat cgtagccaat gatagcttca
     1981 gcaatgatgt tgtttacgtt gtcaacagct ttttgtgtac caagaccacc gtaacgagat
     2041 ttgtcaccgt cgcgaagttc aactgcttcg tgttcaccag tagaagctcc tgatggaacc
     2101 ataccacgtc cgaaagcacc tgattcagtg taaacttcta cttcaagtgt tgggttaccg
     2161 cgtgagtcta ggacttcgcg agcgtaaaca tcagtaataa ttgacatttt ttactctcct
     2221 tatgagttaa attttttaca cctctataat accttaaaac ccctcctttt tcaagaaaaa
     2281 acgttatctt tgtgcaactt ttccttaact ttataaagta atcgctttct tttgtctgtt
     2341 ttattccaac ttttatgata tactgttttc atgacagatt tatcaaaaca attacttgaa
     2401 aaagctcatg gtgggttaaa aataaatccg gatgagcaaa gacgctatct tggtactttt
     2461 gaggaaagag ttcttggata tgtagatatt gacacagcaa atagccctca gttagaaaaa
     2521 ggctttttat ttattttaga aaaccttcag gaaaaagcag agccactatt tgtgaagatt
     2581 tcaccaacta tcgaatttga taagcaagtt ttctacttaa aagaagcaaa agaaactgat
     2641 agtcaagcca ccatagtatc tgaagagcat attacttctc cttttggcct ggttattcat
     2701 agcaatgcac cagttcaagt agaagaaaaa gaccttcgac ttgcttttcc aaaactttgg
     2761 gaagttaaaa aggaagaacc agccaaaaca tccttatgga agaaatggtt tagctaaatc
     2821 ttgcacatat ttaataagtg cccaatattg gcagccgtgc gctccagata gagactggca
     2881 tttttcaaac tatcttctaa aggttcactt ttctctaaaa tagaaaagac agcttggata
     2941 ttttcaaatg gtaggggagg taaatcttca gcaagactac cgcaaatagc aataacagga
     3001 actccaacag gggttctttt tgcaacacct ataggcgctt tcccagcaaa gctttgacta
     3061 tcaagtcttc cttctccaac aacaaccaag tcagcatctg aaactttctt atcaaagttg
     3121 attaagtcca agcaggtatc aattccagac acgatacttg cctgagcaaa ggcacacaaa
     3181 ccaccagcaa ggcctccacc tgctcctgct cctttaattt ctaatgttgc aggtgagaat
     3241 ttttcataaa aatcttggat cgcctgatct acgactgcaa acatagtcgg atgtagacct
     3301 ttttgattgc caaaagtgta agtcgcacct tgatgaccac ataagggact cacgacatct
     3361 gctaaaatat gaatttgaac accttcagga attttatagc aattttctgt tgaaacagaa
     3421 gctaagttta ataaggattg accggaagca ggcaagacat ttccatccct atcataaaat
     3481 tgataaccta aaccagcagc aatccccagt cctccatcat tactggccgt gccaccaaca
     3541 ccgatataaa tatctttaat ccctttagaa atgagatgga gaatcaactc tccaatacca
     3601 caagtttgga tttgaagtgg atttcgtttc tctagcggaa tttttccaag accaaccaag
     3661 ttagctactt caaatagtgc cagttcccct ttttgaaaat agcgcatggc ttctttttgt
     3721 ccaaaagggt ctgtcacttg gatccatttt tcttttaggt caagagaatg tcggatagca
     3781 tctacagtac cttctccccc atcaccaaca gggcagagga gacattctac atctgctatc
     3841 gattgttgga agcctctttt tattgcttca gctacctgtt gagctgtcaa gctttcctta
     3901 aacgaatctg gtgcaattac aatcttcata ttttccctca ttctaaacag tcaatcaaag
     3961 gaagaacttc taaaaaatcc ctcttgtcaa catgatgtgg tatttctttt ttgagcactt
     4021 ctttggcaca aaaggcgatt cctaactccg ccgacttcaa cattaataga ttattgaccc
     4081 catcaccgat tgccaccgtt ctttctttag aaagttttag tttctttctc catttttcca
     4141 gagtctcttt tttgacctgg ggacttataa tttgtccaac taattttcct gttaaaagac
     4201 cttctttgac ttcaagctag ttggcagtga aataggcaat accaagggat tttgctaatc
     4261 tctccaacta ttggtgtaaa tccaccagac accagaccaa ctaggatgcc attcttttgg
     4321 agaatagaga tgaactctgg gacatttagc gatagatgaa ttgagttgaa gacgttatca
     4381 aagaccaaaa taggaagacc ttccaacaag gacactcttt ttcttaaact gctttcaaag
     4441 accaactctc ctcgcattgc tcgacttgta atctgcgaaa tttccgcctc atgacctgcc
     4501 tctctcccta aaagatcaat cacttcttct aggattaagg ttccatctac atccaaaaca
     4561 cacaagcctt ttacttgaga catcagttct cctctctaaa cagcctaaaa atcgtatgaa
     4621 gtcatcatac gattttatct attaattaac taaactatgg tacaagtcaa ggtatgactt
     4681 gcaggctgta tcccatgaga agtcactctc catagcttgt ttttgtaggt ttctccaaat
     4741 gtctggatgg tttctataca agtccaatgc tgtttggaaa gtccaattta accaataagg
     4801 agatagattg tcaaagctaa agccagtacc gcttccttcg attggattga aagcgcgaac
     4861 tgtatctcgc aagcctccaa cttcatggac caatggcaag gttccataac gcatagccat
     4921 catttgagac aagccacacg gttcaaaacg acttggcatg aggaagaggt cacaagcagc
     4981 gtagatttcc tgagcaagtt tgacatcaaa agtgatattt gttgatagct tgtctgggta
     5041 aatctgagca aaccatgaga aagctccttc aaaggctgga tcgccagttc ccaaaagaac
     5101 aatctgaaca tcttcttgca agatatggtg aagactttcg accaccacat caaaaccttt
     5161 ttgacgtgtc aaacgagaaa caattcccac cagtggaacg tctgctctaa caggcaagcc
     5221 aactctttct tgcaattttg ccttattttt ggctttccca gacaaatctt cctgattgaa
     5281 atgatagtct aaaagagcat ccgtctgagg attataaaga tcagcatcaa tcccattcac
     5341 gataccagat actttaccag actccatttt aagaatctga tccaaattac atccaaactg
     5401 actagtcata atttcatgag catagctagg tgaaacggtt gaaacacggt tcgcatagag
     5461 aatacctgcc ttcatccagt tcagacagtt gttccatcga agggtgccat cagcgtaacg
     5521 ttcaaagcca actccaaaca aatcacccaa cattccttct gaaaattgtc cttggaattc
     5581 taaattatga atggttaaaa ctgtttcaat gtcctcatag gcttgaatcc aacggtattt
     5641 ttccttcaac aagaaaggaa tcatagctgt atggtagtca tgaacatgga gaagatcagg
     5701 aataaagtca atcctttcca tagcctcaat ggcagccagt tggaaaaagg caaagcgttc
     5761 tccgtcatca aaatcaccgt aaacatgacc acggaagaaa taatattgat tgtcaataaa
     5821 gtagaaggtt acaccattta atactgtttt cttaattcca caatactgtc tgcgccaacc
     5881 aacgctcacc tcaaaatgaa gcacatcttc aatctgattt ccaaatttag cctctaccat
     5941 atcatagtag ggtaaaatca ctgcaacttc gtgcccagct tttaccagtg attttggaag
     6001 agcgccaatg acatctccca aaccacctgt ttttgaaaag ggtgcaccct ctgctgctac
     6061 aaataaaatt ttcatgaatg aatatcctct gttactttag cacctttctt aaccacaact
     6121 ggatgttctg cagttcctcg aatcacaaca ccatgctcaa cttcaacccc tttgtccaag
     6181 atagcatatt cgacctgagc cccttctcca ataacaacac gagggaagag aaggctatct
     6241 ttaaccaagc tatccttatg gacatgaata ttacgtgata gaacagaatt agctacttga
     6301 ccttcaataa tactaccaga ggcaaactga gaagtgctta ccttagatgt attagcatag
     6361 taagttggct cttcgttttt gacctttgta taaatctttt ggtttggtga gaaaagagaa
     6421 tagaattttt gtgattcaag catatcgata ttcgcttgat aataagattt aacagagtga
     6481 atattggcta gatagcccgt gtactcgtag gcgaaagctc cctcttttac agccaaatcc
     6541 cgtaaaacat agcgcaattt ctctggatgt tcttttttag cttcttcttc caagtgttca
     6601 atcaaccaag gtgtatcaac gacaaagata tctgtagaca tattgaacgt ttcagctgtt
     6661 gacttgctat caaagagttt atgagaaaga acatggtctg tttcatctac atccaagatt
     6721 gcatttactt ctgaaatatc tttcttagct agttttttat aaactacagt gataggctct
     6781 tttgttgtac tatgtaggtg gaaaacttgg ttcaaatcaa tgttaataag aacatcgcag
     6841 ttgagggcaa ccgtttggtt tgagccagaa cgtttcaaat aagtaagaag ctgttggtag
     6901 tattcttttc caactgtact actttctaca cgggtattgt aaattcctag atagtaatgg
     6961 ctaagaaggg ttgataagcc ccactcgcgt cctgaacgaa tatggtcaaa tactgagctg
     7021 atattatcct gctggaaaat accaaagaca ctacgaacac ctgcattagc aaggcttgaa
     7081 agtgggaagt caatcaaacg atatttccca ccaaatggca aacttgctac tggacggtgg
     7141 tccgtcaatg tcgacatatt gtgaaaacca actgtatttc ctaaaatggc agaatattta
     7201 tcaatcttca tctgttgcta cccccactac ttcattatat cctacaactt gtacttcatc
     7261 tgttccatca atttcgacac cgtcagaaat aatcgcacct tcaccaataa tggcacgttt
     7321 aatcttagct ccttgaccaa tgatagctcc actcatgata actgaatcaa ggacttccgc
     7381 tccttcgcga acttgcgcgc ctgttgaaag gatagaatgt ttaacagttc catcaacgaa
     7441 acatccgtct acaactaatg agtcttccac atgagcattt gccccgagga agtttggtgg
     7501 tgaaatcaag tttcttgagt aaatcttcca ttgacggtta cgactatcca aggcattttc
     7561 tggagaaata tactccatgt tcgcttccca aagtgactca atagtaccaa catctttcca
     7621 ataaccacta aattcgtaag cataaacact ttcacctgac tcaaggtaat ttggaatgac
     7681 atttttacca aagtctgaca tgccaacctt gctcttttca gcagcgacta acatattacg
     7741 aaggcgttgc caatcaaaaa tgtagattcc catagaagct tttgtagatt taggttgagc
     7801 tggtttttct tcaaattcaa caatacgatt gttagcatct gtgttcatga taccaaaacg
     7861 gcttgcttct ttaagaggga cgtctaaaac tgctactgtc aagctggcat tattatcctt
     7921 atgagactgg agcatatcat catagtccat tttgtagatg tggtccccag acaaaatcaa
     7981 gacatactca ggattgacac tgtcgatata gtcgatattt tggtaaatag cgtgactagt
     8041 tccctcaaac caacgatttc cttcacttgc agaataaggt tgaagaatag agacgcctga
     8101 attaataccg tctagtcccc agcttgaacc attcccaata tggttgttga gagcaagtgg
     8161 ttgatactgt gtaacgaccc caacattatg aatccctgag ttggcacagt ttgatagggc
     8221 aaagtcaatg atacggtagc gcccaccaaa ttgcacagct ggttttgcga tgctttgagt
     8281 gagtttaccg agacgagttc cttgcccacc agcaagaatc aaagctaaca ttttattttt
     8341 cattttctac tcctttttgg tttttatttg tgacggtttt agtagatttc aagcgacgtt
     8401 tgattttcca tacacttgct cccatagccg gtagagtaaa ggttaaggtc tgctcataat
     8461 ctttccatag gccttcttgc gtttgaacag tttgattatg ttctttccaa acgcctcccc
     8521 actcttccaa ctcagtattc catacttctt cgtaaattcc tgcaacgggt agtccgattg
     8581 taaaatcttt ccgctcaaca ggtaccatgt taaagataca gactaacatt tctccctttt
     8641 tacccttacg aataaaggaa agaacactct ggtctcgatt atccgcatca atgatttcaa
     8701 taccatcata gctggtatcg atttcccaca gacagcgatg atctttgtaa aactggttta
     8761 gatgagaagt gaaatacttc atcttagcat tcattgggtc ttctaggtta gaccattcca
     8821 actgttcttc agatttccat tctaggaatt gaccgtattc gctacccatg aagagcaatt
     8881 tcttaccagg gtgacaaatt tggtacgtat agagattgcg caagcctgcg aattgattgt
     8941 aacgatctcc ccacatctta tgcatcatac tcttcttgcc atgaaccact tcatcgtgcg
     9001 agaatggcaa gagataattc tccttgaaaa catacataaa gctgaaagtc accaggttaa
     9061 agtcatattt acgataaatc ggatcttctt cgtagaaacg gaggatatca ttcatccagc
     9121 ccatgttcca tttgtagtca aatcctagac caccaatctc tttcattccc gtaatcttgg
     9181 tcgcagacga actttcttct gcaatcatca tcacatctgg atattctaac ttaataactt
     9241 cattcaagcg ttgaagaaaa taataacctt catagttaag atttccgcca tctttattag
     9301 gtgtccatgg agcattatca tagtccaaat agagcatgtt gctaacagca tccacacgaa
     9361 taccatccaa atgatagaca tcaatccaat gcttaatgca agaaattaag aaggactgga
     9421 cttcattttt tccaaggtca aaattaaggg caccccaacc atggttatga gccttattat
     9481 ggtcttggta ttcaaaagtc ggtgtcccat cataataggc taaggcatca tcgttgatgg
     9541 taaagtgacc tggtacccag tccacaataa ccccaatatt atgggtatga cactcctcga
     9601 caaaatcttg aaactcctct ggtctgccat aagcatgctc taaagcgaag taacccataa
     9661 gctgataccc ccaactcaag cccaaaggat gggacatcaa gggcataaac tcaatatgag
     9721 tatagttcat ttcaacgaga taaggaatga gttcatcctt gagctgggca aaactataag
     9781 gactgccatc aggatttctc ttccaagagc cagcatgaac ctcgtaaata ttgacaggac
     9841 gttcaacaaa gccccaacgt tttcttcgtg ccagccaaag tccatccctc catttcttat
     9901 caggaagctc tgttacgatt gcccctgttc ctggacgagc ctcatacctg acagcaaaag
     9961 ggtcaatctt catcagttga tgaccatttt gacgtgtgac atgatatttg taaatatgcc
    10021 cttcttgagc catattggta aagacttccc agaccccaaa gtcatttctt accattggaa
    10081 tctgattttc aatccagttg gtaaaatcac caaccaagtg aacagcctga gcattaggtg
    10141 cccaaacacg gaaggtatag ccatgctctc catttagttc ttccctatgt gctcctagat
    10201 aatgttggag ataaaaattt tcacccgtca taaaggtttt taatgcttct ctattatcca
    10261 tatactcccc ttctcctgta agcgttttct atgtttttat tatactacct ttttagagaa
    10321 gattcaagta aattactata cttctttaat tattttgaaa atctacaaca agttcactta
    10381 ctcgttcaat tgtaaatcaa tattttttca aaaaattgcg aaaacgcctt tctttttcta
    10441 ctatagtgaa atgaaataaa acatgcgcaa atcgatcagg acagtcaaat cgatttctaa
    10501 caatgt
//
LOCUS       DAVLUM010000068        10468 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLUM010000068 DAVLUM010000000
VERSION     DAVLUM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.068"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(338..2596)
                     /gene="glgP"
                     /locus_tag="VYN42_001690"
     CDS             complement(338..2596)
                     /gene="glgP"
                     /locus_tag="VYN42_001690"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1462738.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(2622..4139)
                     /gene="malQ"
                     /locus_tag="VYN42_001691"
     CDS             complement(2622..4139)
                     /gene="malQ"
                     /locus_tag="VYN42_001691"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1462739.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            4689..5960
                     /locus_tag="VYN42_001692"
     CDS             4689..5960
                     /locus_tag="VYN42_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1462740.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6071..7363
                     /locus_tag="VYN42_001693"
     CDS             6071..7363
                     /locus_tag="VYN42_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1462741.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            7365..8207
                     /locus_tag="VYN42_001694"
     CDS             7365..8207
                     /locus_tag="VYN42_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1462742.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            8460..9260
                     /locus_tag="VYN42_001695"
     CDS             8460..9260
                     /locus_tag="VYN42_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1462743.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            9270..10256
                     /locus_tag="VYN42_001696"
     CDS             9270..10256
                     /locus_tag="VYN42_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1462744.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT         3049 a         2250 c         1980 g         3189 t
ORIGIN      
        1 aattatatta taatacttta tgtaagcgaa tataatagat gtgaggtaac caactacgaa
       61 aaaatataag gctgaagaca gtaaaaacca gcatttaaag ccttcactgt atctaggatt
      121 tccctatttt tagacaagat tgacccaaat ccacagcatt taaaaaagcg aatttcaatt
      181 gaaactcgct tttttacaag atgtattagt ataaatttgt atcttatact caatgaaaat
      241 caaagagcaa actaggaagc tagccgcagg ttgctcaaag caccgctttg aggttgcaga
      301 taaagctgac gtggtttgaa gagattttcg aagagtatta gttcaagtgc cagatgtctt
      361 cgttatactg agcgattgta cggtcagatg agaagaatcc tgctttagaa atgttaacga
      421 tgactttatc caaccatgcg tcacggtctt cgtagtcagc aagcatttgc tctttgactt
      481 tgatgtagtc ttccaaatca agaagagtca tgaaccagtc tttgttgatc aattcattgt
      541 aaagacgttc caagcgctct ttgtttccag ctgcaagaac tgcatcacta acgatgaagt
      601 caaccaatgg tttgatagct tcacgagcgt agaattcgct tgatttgtaa gctgcttttg
      661 cgtaaaggtc gataacagtt tctgaatttt caccgaagat gtagatgttt tcttctccaa
      721 ccaactcagc gatttccacg ttagcaccgt ccatagtacc aagtgtcaaa gctccgttca
      781 acatgaattt catgttacca gtacctgaag cttctttaga agcaagtgag atttgttctg
      841 agatatcaca tgctgggata aggaaacttg ctgcagtaac gttgtagttt tcaaccataa
      901 ctacttgcaa gtgtggagct actgctggat cgttagcaat aacttctgac atgcaaagga
      961 ttaaatggat aatgtcttga gcgattgtgt aggctggagc tgctttacca ccaaagaaga
     1021 ttgtgattgg acgagcaggg atgttaccag ctttgatgtc aaggtatttg tggatcacgt
     1081 acaaagcgtt catttgttgg cgtttgtact cgtgaagacg tttgatttgg atatcaaaga
     1141 tagaatttgg attgatttcc acaccttggt gttctttcaa gtgacgagcc aatttacgtt
     1201 tgttgtgagc cttgatgctt tccaattttt ctttgacagc tgctttgtct tcataagaca
     1261 acagtttttc aagctcatct gcttcatggt gccaaccatc tccaagaatc tcatccaagt
     1321 agtgagacaa tcttgggtta gcatgcataa gccaacgacg gaaagtgata ccgtttgttt
     1381 tgttgttgaa cttttctggg taaaggtcgt agaaggcttt caactcagaa tttttcaaga
     1441 tttcagtatg gagtgctgca accccgttaa cactgtatcc gtagtggata tccatgtgag
     1501 ccatgtgaac acgtccgctc tcatcgatga tttgaacagc tggatctttg tactctgcct
     1561 tcacacgacg gtccaattct tcgatgattg gtaccaagtg aggaaccact tcttgcaaga
     1621 attcaagagg ccatttttca agcgcttcag caaggattgt gtggttagtg taggcagtca
     1681 tgctacgaac aattgagatt gcttcgtcaa gatcgatacc acgtgcagtc aaaagacgaa
     1741 tcaattcagg aatcaccatt gatgggtgag tatcgttgat ttggacaact gcgtagtcag
     1801 caaggtcatg caagttgctt cctttttcga ttgcttcgtc gatgatcaat tgcgcaccgt
     1861 ttgaaaccat gaagtattgt tggaagatac ggagcaattc accttgacgg tcactatcat
     1921 ctgggtaaag gaagagagtt aagttgcgag cgatatctgt cttgtcaaag ttgataccat
     1981 ctttaataat agaagaatca actgaatcca agtcaaacaa acgcaagcgg tttttagtcg
     2041 ctgtttcata accagtaaca tcaatatcgt aaagagttga tgtcaaagta aagtctgcaa
     2101 atggtacttg gtagctacgg cttgagcgaa ccaaccagtt ttgctctgtc aaccatgcat
     2161 ttggaattgt ttcttgttgg ttgtttttaa gaacttgttg gaaaagacca aagtggtagt
     2221 taagaccaac accgtcacca ttcaaaccaa gagtagcaat tgagtcgata aagcaggcag
     2281 ccaaacgtcc caaaccacca ttaccaagag atggttccaa ttcaacttct tcaacttcga
     2341 tcaagtcttt acctgcagct gcaagttctt ttttaacatc gtcgtaaaga ccaaggttaa
     2401 tcaagttgtt tgacaagagt ttaccaatca agaactcagc tgagatgtag taaacttttt
     2461 tcttaccagt gttgactggt ttttggctgc ttgcaagctt gctgtagtta agaagagcaa
     2521 ggtaaagctc ttcattgcta cattctgcaa tggttttatt gtaacgattt tgtacaaatt
     2581 cttgtagtga taacatgttt agttgtctcc tgattattgt cttatttctt taaatctacc
     2641 aaattttcat taattcggcg ataaattgtt gtcaagtcaa gcaaaccttc ctcgacagct
     2701 ggtgtcaatt gatcttcagt catacgccaa gaccagtttc caccaagggt agatgggaag
     2761 ttcatacgag ctgcctcatc caattctagt aaatcttgca tagttgcaat tgccataaag
     2821 ctaactgatg aaaatactgt acgaagcata gcgtgtacca ctgtttcgta ttctttacgg
     2881 ttcgtgtaac gagccatgta ctcacgagtc gcatcatcaa tctcattacg gtaccaacca
     2941 agaaccgtat tgttatcgtg tgttcctgtg tacataactg agttagcagg tgccaagtgt
     3001 gggctatcaa tgctttcgtc ttctgggttg aaggcaaatt gaagaatctt cattcctggg
     3061 aagccagtac gttcacgcaa ttcgatcact tcatctgtca tgaagccaag gtcttctgcg
     3121 atgatgttta gctcaccaag ttcttcctta acggctgcaa aaagcttgta gcctggacct
     3181 ttcacccact caccaggtgc tgctgtatcg gaaccagcag ggatttccca gtaagattcg
     3241 aagccacgga agtggtcgat acgaacgata tcgtagattt tgaagctttc acgcaagcgt
     3301 tcaatccacc atttgtagcc gtctttgtcc attgcttccc agtcatagat tgggttaccc
     3361 caaagctgac cagttacaga aaactcatct ggtgggcatc ctgcgataca agtagcctta
     3421 ccattgacat ctgttttgaa gagatgtgga tttgcccaca tatcacttga atcttccgct
     3481 acgtagattg gcatgtcccc aacgatttcg atgtggttgt cgttagcgta agctttcaat
     3541 ttcaaccatt gttggaagaa gaagtattga gtcacacggt ggtaaaccaa cttgtctgcc
     3601 aattgctcac gatagctttc aagtgctgaa gctttacgag cacgagcatc tgcatctggc
     3661 cattcagtcc aagcaagatt gtcaaaatac tctttgatag ccatatactc agcaaagagc
     3721 tcaagccatg attggttgtc ttgagcaaat ttctcaaaat ctttaacatc tccgacttca
     3781 aagaaacgtt tcacagcttt ttctaaaaga ggacgacgtg catagtagat tttagcatag
     3841 tcaacttcag acgcatcgct accaaagtca actccttcaa ggtcacttgc ttccaacaaa
     3901 ccttgctcca ccaagatatc taaatcgata aaatgagtgt ttcctgcgaa ggctgagaaa
     3961 gattggtaag gagaatcccc gtaactagtt gctcctaatg gaaggatttg ccagtaacgt
     4021 tgttttgtac ggaccaagaa atcaacgaag tcgtaagcac tttgaccaaa tgatccgatt
     4081 ccgtaagctc ctggaagaga agagatgtgc atcaacacac cactttgacg ttttttcata
     4141 atagcacctc gtgtgttaaa ataatggaac gttgcgtatt ttgcagacgc aaacgtttgc
     4201 gttacttata agtatactcc ttttcaagca taattgcaag cgtttttaaa aaactttttt
     4261 gattattttt aaggagacta actcatttta gcaaagataa cttaaaacta tctaatccta
     4321 aggtttgact ctcacgagac agtctacaaa gtacaaaacc tccttaggga gcttgaattt
     4381 atatgtaaca aagcacaaac gtccatagaa aatagatagg gattagaacc agggaggtag
     4441 cccctcctgg tttccctctt tagacagatt ccatatattt ttattaaaaa tactgtattc
     4501 ttatctattt catacttttc ttctattaaa atgcaaaatt atgctatcaa atcaagctta
     4561 aaaatttttt aaaattttta caaaaaatac ttgcaaccgt tttctatttg tgctatacta
     4621 agctcataaa ggaaaacgtt tgcgtttcct tatcaataaa acttgctatt ctttgggagg
     4681 aatacactat gtcatctaaa tttatgaaga gcactgcggt gcttggaact gttacacttg
     4741 ctagcttgct tttggtagct tgcggaagca aaactgctga taagcctgct gattctggtt
     4801 catctgaagt caaagaactc actgtatatg tagacgaggg atataagagc tatattgaag
     4861 aggttgctaa agcttatgaa aaagaagctg gagtaaaagt cactcttaaa actggtgatg
     4921 ctctaggagg tcttgataaa ctttctcttg acaaccaatc tggtaatgtc cctgatgtta
     4981 tgatggctcc atacgaccgt gtaggtagcc ttggttctga cggacaactt tcagaagtga
     5041 aattgagcga tggtgctaaa acagacgaca caactaaatc tcttgtaaca gctgctaatg
     5101 gtaaagttta cggtgctcct gccgttatcg agtcacttgt tatgtactac aacaaagact
     5161 tggtgaaaga tgctccaaaa acatttgctg acttggaaaa ccttgctaaa gatagcaaat
     5221 acgcattcgc tggtgaagat ggtaaaacta ctgccttcct agctgactgg acaaacttct
     5281 actatacata tggacttctt gccggtaacg gtgcttacgt ctttggccaa aacggtaaag
     5341 acgctaaaga catcggtctt gcaaacgacg gttctatcgc aggtatcaac tacgctaaat
     5401 cttggtacga aaaatggcct aaaggtatgc aagatacaga aggtgctgga aacttaatcc
     5461 aaactcaatt ccaagaaggt aaaacagctg ctatcatcga cggaccttgg aaagctcaag
     5521 cctttaaaga tgctaaagta aactacggag ttgcaactat cccaactctt ccaaatggaa
     5581 aagaatatgc tgcattcggt ggtggtaaag cttgggtcat tcctcaagcc gttaagaacc
     5641 ttgaagcttc tcaaaaattt gtagacttcc ttgttgcaac tgaacaacaa aaagtattat
     5701 atgataagac taacgaaatc ccagctaata ctgaggctcg ttcatacgct gaaggtaaaa
     5761 acgatgagtt gacaacagct gttatcaaac agttcaagaa cactcaacca ctgccaaaca
     5821 tctctcaaat gtctgcagtt tgggatccag cgaaaaatat gctctttgat gctgtaagtg
     5881 gtcaaaaaga tgctaaaaca gctgctaacg atgctgtaac attgatcaaa gaaacaatca
     5941 aacaaaaatt tggtgaataa aaaatttgtt caaggggggt ggaaatcaaa tccccctttg
     6001 aatttatcaa tagagacaca aataatttag ctttcttata aaaaagtagt atcctatgaa
     6061 aggagttaat atggaaaagc aacaacctag taaagcagcc ctgctgtcta tcattcctgg
     6121 gttaggacag atttacaata aacaaaaagc caaaggtttt atcttccttg gtgtaaccat
     6181 cgtatttgtc ctttacttcc tagcacttgc aacccctgaa ttgagcaacc tcatcactct
     6241 tggtgacaaa ccaggtcgtg ataattccct ctttatgctg attcgtggtg ccttccatct
     6301 aatctttgta atcgtttatg tactctttta tttctcaaat atcaaagatg cacatacgat
     6361 tgcaaaacgc attaacaatg gaattccagt tccacgcaca ctcaaagaca tgatcaaagg
     6421 gatttatgaa aatggcttcc cttacctctt gatcattcca tcttatgttg ccatgacctt
     6481 cgcgattatc ttcccagtta tcgtaacctt gatgatcgcc tttaccaact acgacttcca
     6541 acacttgcca ccaaacaagt tgttggactg ggttggtttg accaacttta caaacatttg
     6601 gagcttgagt accttccgtt ctgcctttgg ttctgttctt tcttggacta tcatttgggc
     6661 tttggcagct tctactttac aaatcgtaat tggtatcttc acagctatca ttgccaacca
     6721 accatttatc aaaggaaaac gtatctttgg tgttattttc cttcttcctt gggctgtccc
     6781 agccttcatc actatcttga cattctcaaa tatgtttaac gatagtgtcg gtgctatcaa
     6841 cactcaagta ttgccaatct tggctaaatt ccttcctttc cttgatggag ctcttattcc
     6901 ttggaaaaca gacccaactt ggactaagat tgccttgatt atgatgcaag gttggctcgg
     6961 attcccatac atctacgttt tgactttggg tatcttgcaa tctattccta acgaccttta
     7021 cgaagcagct tatattgacg gtgccaacgc ttggcaaaaa ttccgcaaca tcactttccc
     7081 aatgattttg gctgttgcgg cacctacttt gattagccaa tacaccttca actttaacaa
     7141 cttctctatc atgtacctct tcaatggtgg aggacctggt agtgtcggag gtggagctgg
     7201 ttcaaccgat atcttgatct catggatcta ccgtttgaca acaggtacat ctcctcaata
     7261 ctcaatggcg gcagctgtta ccttgattat ctctatcatt gtcatctcaa tctctatgat
     7321 cgcattcaag aaactacacg catttgatat ggaggacgtc taagatgaat aactcaatta
     7381 aactcaaacg tagactgact caaagcctta cttaccttta cctgattggt ctatcaattg
     7441 taattatcta tccactgttg attaccatta tgtcagcctt taaagcaggt aacgtctcag
     7501 cctttaaact agatactaat atcgacctca attttgataa ctttaaaggc ctcttcactg
     7561 aaaccttgta cggtacttgg tacctcaaca ctttgattat cgccttaatt accatggctg
     7621 ttcaaacaag tatcatcgta cttgctggtt atgcttacag ccgttacaac ttcttggctc
     7681 gtaaacaaag tttggtcttc ttcttaatca tccaaatggt gccaactatg gccgctttga
     7741 cagccttctt cgttatggcg cttatgttga acgcccttaa ccacaactgg ttcctcatct
     7801 tcctctacgt tggtggtggt atcccgatga atgcttggct catgaaaggc tacttcgata
     7861 cagtgccaat gtctttagac gaatctgcaa aactagacgg tgcaggacac ttccgccgct
     7921 tctggcaaat tgttctacca cttgttcgcc caatggttgc cgtacaagct ctctgggcct
     7981 tcatgggacc tttcggggac tacatcctct ctagtttctt gcttcgtgag aaagaatact
     8041 ttactgttgc cgtaggtctc caaaccttcg ttaacaatgc gaaaaacttg aagattgcct
     8101 acttctcagc aggtgctatc ctcatcgccc ttccaatctg tattctcttc ttcttcctac
     8161 aaaagaactt tgtttcagga cttacaagtg gtggcgacaa gggataattt atccccgcca
     8221 ccctttttca ttttatactc ttcgaaaatc tcttcaaacc acgtcagctt tatctccaac
     8281 ctcaaagttg tgctttgagc aacctgtggc tagtttgcac tttgattttc attgattatt
     8341 agcaattgtc actgtaaata atatccttgt agcaagcaat ttttctccta gacttgaaat
     8401 aaagcgcatt tctctatata ataatactca tatagaaaac accttttaga aagataccta
     8461 tgcttccata tccattttcc tatttttcaa gtatttgggg gtttcgtaag cccctgtcca
     8521 aacgtttcga gctcaactgg tttcaacttc tctttaccag tatcttcctt atcagcttgt
     8581 ctatggtacc cattgctatc caaaacagct cccaggagac ctatccgcta gaaactttta
     8641 tcgataatgt ctatgaacct ctgacagata aggttgtcca ggatctctct gaacatgcta
     8701 caattgtcga tggcacatta acttatactg gaacagctag tcaagcccct tctgttgtga
     8761 ttggtccaag tcaaatcaag gaattaccta aggacttgca actgcatttc gatacaaatg
     8821 aactagtcat cagcaaggaa agcaaggaac tgacccgcat ctcttaccga gccattcaga
     8881 ctgagagttt caaaagcaaa gacagcttga cccaagcaat ttctaaagac tggtaccaac
     8941 aaaatcgtgt ctatatcagc ctcttcctag ttctcggtgc gagcttcctc tttggtttga
     9001 atttctttat cgtctctcta ggagctagtc ttctccttta tatcactaag aaatcacgcc
     9061 tcttttcatt tagaaccttt aaagagtgct atcactttat cttgaactgt ttaggattgc
     9121 cgactctgat tacacttatt ttgggattat ttggccaaaa tatgacaacc ctgattactg
     9181 tacaaaatat tctttttgtt ctgtatctgg tcactatctt ttataaaaca catttccgtg
     9241 atccaaatta ccataaatag gagattttta tgcccgttac gattaaagac gtggccaagg
     9301 ctgctggtgt ttcgccttca accgtaaccc gtgttattca aaataaatca accattagcg
     9361 acgaaacaaa aaaacgcgtt cgcaaagcta tgaaggaact caactaccac ccaaacctca
     9421 acgctcgtag cttggtaagc agctatactc aggttatcgg attagttctt cctgatgact
     9481 cagacgcctt ctaccagaat cctttctttc catcggttct acgtggcatc tctcaagtcg
     9541 catctgaaaa ccactatgcc attcagatag caacagggaa agatgagaag gagcgtctca
     9601 acgctatttc acaaatggtc tacggcaagc gtgtagatgg gctaatcttt ctctatgccc
     9661 aagaagaaga ccctctcgta aaactcgtcg cagaagaaca gttccccttc cttatcttag
     9721 gtaaatctct atctcctttc atcccacttg tcgacaacga caatgttcaa gctggttttg
     9781 atgcgactga atatttcatc aaaaaaggct gcaaacgcat tgcctttatc ggaggaagta
     9841 aaaagctctt cgtgaccaaa gaccgtttaa caggctatga acaggcgctt aaacattaca
     9901 aacttaccac tgacaacaat cgcatctact ttgccgacga gtttctggaa gaaaagggct
     9961 ataaatttag caagcgatta ttcaagcacg atccacaaat tgatgctatc atcacaaccg
    10021 atagcctcct agctgaaggt gtttgtaact atattgccaa acaccagctg gatgtccctg
    10081 ttctcagctt tgactcggtt aatcccaagc tcaacttggc agcctatgtc gatatcaata
    10141 gtttagagct tggtcgtgtt tcccttgaaa ctattctcca gattattaat gataataaaa
    10201 acaataaaca aatttgttac cgtcaattga tcgcccacaa aattatcgaa aaataagaga
    10261 ctgggcaaaa agtcgttaaa agcaaaaaac gcatactatc aggtattgaa aaaacttgat
    10321 actatgcgtt ttattgtggg aagatttact tccttttcta ctgaaattga gtcttttccc
    10381 aagatctttt tatactcaat gaaaatcaaa gtgcaaacta ggaagctagc cgcaggttgc
    10441 tcaaaacact gttttgaggt tgtggata
//
LOCUS       DAVLUM010000069         9785 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLUM010000069 DAVLUM010000000
VERSION     DAVLUM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.069"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            116..5056
                     /locus_tag="VYN42_001697"
     CDS             116..5056
                     /locus_tag="VYN42_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1462745.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGH
                     EVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNELTEAHKALNGQEKFTEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            5146..6342
                     /locus_tag="VYN42_001698"
     CDS             5146..6342
                     /locus_tag="VYN42_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1462746.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            6478..7005
                     /locus_tag="VYN42_001699"
     CDS             6478..7005
                     /locus_tag="VYN42_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1462747.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            7082..7438
                     /gene="glnR"
                     /locus_tag="VYN42_001700"
     CDS             7082..7438
                     /gene="glnR"
                     /locus_tag="VYN42_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1462748.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            7475..8821
                     /gene="glnA"
                     /locus_tag="VYN42_001701"
     CDS             7475..8821
                     /gene="glnA"
                     /locus_tag="VYN42_001701"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1462749.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(8917..9036)
                     /locus_tag="VYN42_001702"
     CDS             complement(8917..9036)
                     /locus_tag="VYN42_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1462750.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            9525..9785
                     /locus_tag="VYN42_001703"
                     /pseudo
     CDS             9525..9785
                     /locus_tag="VYN42_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3166 a         1774 c         2134 g         2711 t
ORIGIN      
        1 ttgtctaaaa atgttttagg ataaaaatgt gattatcatg attctagagt taaaaaacta
       61 cagaatataa agcgctttct tgaaaacaac aaaatcaatc ttttaggagg agaaaatgaa
      121 gaatccattt tttgaaagac gttgtcgtta cagtattcgt aagttatcag taggagcctg
      181 ctcgctgatg attggtgctg ttttatttgc tggtccagcc ttggctgaag aaactgcagt
      241 tcctgaaaat agcggagcta atacagagct tgtttcagga gagagtgagc attcgaccaa
      301 tgaagctgat aagcagaatg aaggggaaca tactagagaa aacaagctag aaaaggcaga
      361 aggagtagcg acagcatctg aaactgcaga agcagctagc gcagctaaac cagaggaaaa
      421 agcaagtgag gtggttgcag aaacaccatc tgcagaagca aaacctaagt ctgacaagga
      481 aacagaagca aagcccgaag caactaacca aggggatgag tctaagccag cagccgaagc
      541 taataagact gaaaaagaag tccagccaga tgtccctaaa aatacagaaa aaacattaaa
      601 accaaaggaa atcaaattta attcttggga agaattgtta aaatgggaac caggtgctcg
      661 tgaagatgat gctattaacc gcggatctgt tgtcctcgct tcacgtcgga caggtcattt
      721 agtcaatgaa aaagctagca aggaagcaaa agttcaagcc ttatcaaaca ccaattctaa
      781 agcaaaagac catgcttctg ttggtggaga agagttcaag gcctatgctt ttgactattg
      841 gcaatatcta gattcaatgg tcttctggga aggtctcgta ccaactcctg acgttattga
      901 tgcaggtcac cgtaacgggg ttcctgtata cggtacactc ttcttcaact ggtctaatag
      961 tattgcagat caagaaagat ttgctgaagc tttgaagcaa gacgcagatg gtagcttccc
     1021 aattgcccgt aaattggtag acatggccaa gtattatggc tatgatggct atttcatcaa
     1081 ccaagaaaca actggagatt tggttaaacc tcttggagaa aagatgcgcc agtttatgct
     1141 ctatagcaag gaatatgctg ctaaggtaaa ccatccaatc aagtattctt ggtacgatgc
     1201 catgacctat aactatggac gttatcatca agatggtttg ggagaataca actaccaatt
     1261 catgcaacca gaaggagata aggttccggc agataacttc tttgctaact ttaactggga
     1321 taaggctaaa aatgattaca ctattgcaac tgccaactgg attggtcgta atccttatga
     1381 tgtatttgca ggtttggaat tgcaacaggg tggttcctac aagacaaagg ttaagtggaa
     1441 tgacatttta gacgaaaatg ggaaattgcg cctttctctt ggtttatttg ccccagatac
     1501 cattacaagt ttaggaaaaa ctggtgaaga ttatcataaa aatgaagata tcttctttac
     1561 aggttatcaa ggagacccta ctggccaaaa accaggtgac aaagattggt atggtattgc
     1621 taacctagtt gcggaccgta cgccagcggt aggtaatact tttactactt cttttaatac
     1681 aggtcatggt aaaaaatggt tcgtagatgg taaggtttct aaggattctg agtggaatta
     1741 tcgttcagta tcaggtgttc ttccaacatg gcgctggtgg cagacttcaa caggggaaaa
     1801 acttcgtgca gaatatgatt ttacagatgc ctataatggc ggaaattccc ttaaattctc
     1861 tggtgatgta gccggtaaga cagatcagga tgtgagactt tattctacta agttagaagt
     1921 aactgagaag accaaacttc gtgttgccca caagggagga aaaggttcta aagtttatat
     1981 ggcattctct acaactccag actacaaatt cgatgatgca gatgcatgga aagagctaac
     2041 cctttctgac aactggacaa atgaagaatt tgctctcagc tcactagcag gtaaaaccat
     2101 ctatgcagtc aaactatttt ttgagcatga aggtgctgta aaagattatc agttcaacct
     2161 cggacaatta actatctcgg acaatcacca agagccacaa tcgccgacaa gcttttctgt
     2221 agtgaaacaa tctcttaaaa atgcccaaga agcggaagca gttgtgcaat ttaaaggcaa
     2281 caaggatgca gatttctatg aagtttatga aaaagatgga gacagctgga aattactaac
     2341 tggctcatct tctacaacta tttatctacc aaaagttagc cgctcagcaa gtgctcaggg
     2401 tacaactcaa gaactgaagg ttgtagcagt cggtaaaaat ggagttcgtt cagaagctgc
     2461 aaccacaacc tttgattggg gtatgactgt aaaagatacc agcctaccaa aaccactagc
     2521 tgaaaatatc gttccaggtg caacagttat tgatagtact ttccctaaga ctgaaggtgg
     2581 agaaggtatt gaaggtatgt tgaacggtac cattactagc ttgtcagata aatggtcttc
     2641 agctcagttg agtggtagtg tggatattcg tttgaccaag ccacgtactg ttgttagatg
     2701 ggtcatggat catgcaggag ctggtggtga gtctgttaac gatggcttga tgaacactaa
     2761 agactttgac ctttattata aagatgcaga tggtgagtgg aagctagcta aggaagtccg
     2821 tggtaacaaa gcacacgtga cagatatcac tcttgataaa ccaatcactg ctcaagactg
     2881 gcgcttgaat gttgtcactt ctgacaatgg aactccatgg aaggctattc gtatctataa
     2941 ctggaaaatg tatgaaaagc ttgatactga gagtgtcaat attccgatgg ccaaggctgc
     3001 agcccgttct ctaggcaata acaaggtaca agttggcttt gcagatgtac cggctggagc
     3061 aactattacc gtttatgata atccaaattc tcaaactccg ctcgcaacct tgaagagcga
     3121 agttggagga gacctagcaa gtgcaccatt ggatttgaca aatcaatctg gtcttcttta
     3181 ttatcgtacc cagttgccag gcaaggaaat tagtaatgtc ctagcagttt ccgttccaaa
     3241 agatgacaga agaatcaagt cagtcagcct agaaacagga cctaagaaaa caagctacgc
     3301 cgaaggggag gatttggacc ttagaggtgg tgttcttcga gttcagtatg aaggaggaac
     3361 tgaggacgaa ctcattcgcc taactcacgc aggtgtatca gtatcaggtt ttgatacgca
     3421 tcataaggga gaacagaatc ttactctcca atatttggga caaccggtaa atgctaattt
     3481 gtcagtgact gtcactggcc aagacgaagc aagtccgaaa actattttgg gaattgaagt
     3541 aagtcaggaa ccgaaaaaag attacctagt tggtgatagc ttagacttgt ctgaaggacg
     3601 ctttgcagtg gcttatagca atgacaccat ggaagaacat tcctttactg atgagggagt
     3661 tgaaatttct ggttacgatg ctcaaaagac tggtcgtcaa accttgacgc ttcattacca
     3721 aggccatgaa gttagctttg atgttttggt atctccaaaa gcagcattga acgatgagta
     3781 cctcaaacaa aaattagcag aagttgaagc tgctaagaac aaggtggtct ataactttgc
     3841 ttcatcagaa gtaaaagaag ccttcttgaa agcaattgaa gcggccgaac aagtgttgaa
     3901 agaccatgaa actagcaccc aagatcaagt caatgaccga cttaatgaat tgacagaagc
     3961 tcataaagct ctgaatggtc aagagaaatt tacggaagaa aagacagagc ttgatcgctt
     4021 aacaggtgag gttcaagaac tcttggctgc caaaccaaac catccttcag gttctgccct
     4081 agctccgctt cttgagaaaa acaaggcctt ggttgaaaaa gtagatttga gtccagaaga
     4141 gcttacaaca gcgaaacaga gtctaaaaga tctggttgct ttattgaaag aagacaagcc
     4201 agcagtcttt tctgatagta aaacaggtgt tgaagtacac ttctcaaata aagagaagac
     4261 tgtcatcaag ggtttgaaag tagagcgtgt tcaagcaagt gctgaagaga agaaatactt
     4321 tgctggagaa gatgctcatg tctttgaaat agaaggtttg gatgaaaaag gtcaagatgt
     4381 tgatctctct tatgcttcta ttgtgaaaat cccaattgaa aaagataaga aagttaagaa
     4441 agtatttttc ttacctgaag gcaaagaggc agtagaattg gcttttgaac aaacggatag
     4501 tcatgttatc tttacagcac ctcactttac tcattatgcc tttgtttatg aatctgctga
     4561 aaaaccacaa cctgctaaac cagcaccaca aaacaaagtc cttccaaaac ctacttatca
     4621 accggcttct gatcaacaaa aggctcctaa attggaagtt caagaggaaa aggttgcctt
     4681 tcatcgtcaa gagcatgaaa atgctgagat gctagttggg gaacaacgag tcattataca
     4741 gggacgagat ggactgttaa gacatgtctt tgaagttgat gaaaacggtc agcgtcgtct
     4801 tcgttcaaca gaagtcatcc aagaagcgat tccagaaatt gttgaaattg gaacaaaagt
     4861 aaaaacagta ccagcagtag tagctacaca ggaaaaacca gctcaaaata cagcagttaa
     4921 atcagaagaa gcaagcaaac aattgccaaa tacaggaaca gctgatgcta atgaagccct
     4981 aatagcaggc ttagccagcc tcggtcttgc tagtttagcc ttgaccttga gacggaaaag
     5041 agaagataaa gattaaatat cgaaaaatct tgtgaaatct ttccttatat ttccaaagtg
     5101 tgatataata gtttcgaata aaataaataa aggagttttt gtaacatggc aaaacttact
     5161 gttaaagacg ttgacttgaa aggtaaaaaa gtcctcgttc gtgttgactt caacgtacca
     5221 ttgaaagatg gcgtaatcac taacgataac cgtatcacag cagctcttcc aactattaag
     5281 tacatcatcg aacaaggtgg acgtgcaatt cttttctctc accttggacg tgtgaaagaa
     5341 gaagctgata aagctggtaa atcacttgct cctgtagcag cagacttggc agcaaaactt
     5401 ggtcaagatg ttgttttccc aggtgtcact cgtggtgctg aattggaagc ggcaatcaac
     5461 gctcttgaag atggacaagt tctcttggtt gaaaacactc gttacgaaga tgttgacggc
     5521 aagaaagaat ctaaaaacga tcctgaactt ggtaaatact gggcatcact tggagatggt
     5581 atcttcgtaa acgatgcatt cggtacagct caccgtgcac acgcatctaa cgttggtatc
     5641 tcagcaaacg ttgaaaaagc agttgctggt ttccttcttg aaaacgaaat tgcctacatc
     5701 caagaagcag ttgaaactcc agaacgtcca ttcgtggcta tccttggtgg ttcaaaagtt
     5761 tcagacaaga tcggtgttat cgaaaacttg cttgaaaaag ctgataaagt ccttatcggt
     5821 ggtgggatga cttacacatt ctacaaagca caaggtatcg aaatcggtaa ctcacttgta
     5881 gaagaagaca aattggatgt tgcgaaagct cttcttgaaa aagcaaatgg taaattgatc
     5941 ttgccagttg actcaaaaga agctaacgca tttgctggtt acactgaagt gcgtgacact
     6001 gaaggtgaag cagtttctga aggcttcctt ggtcttgaca tcggtccaaa atctatcgcc
     6061 aaatttgacg aagctttgac tggtgccaaa acagttgtat ggaacggacc tatgggtgta
     6121 tttgaaaacc cagatttcca agctggtaca atcggtgtga tggacgctat cgtgaaacaa
     6181 ccaggagtta aatcaatcat cggtggtggt gactcagctg ccgcagcgat taaccttggc
     6241 cgtgcagaca agttctcatg gattagtacg ggtggtggag catcaatgga acttcttgaa
     6301 ggtaaggttc ttccaggact tgcagccttg acagaaaaat aagattttat aaataaatca
     6361 aagaagagag ggatgaaagt tcctcttttc ttttgcttaa aataaaaacg cttcctctca
     6421 actattactc ataaaaatca ccgatttatg ataaaatgga aatagaaagt tgagattatg
     6481 agttatttta aaaaatataa attcgataaa tcccagttca aacttggtat gagaaccttt
     6541 aaaacaggta ttgctgtttt tctagttctc ttgatttttg gcttttttgg ctggaaaggt
     6601 cttcaaattg gtgctttgac agccgttttt agcctgaggg agagttttga tgagagtgtt
     6661 cattttggga cttcgcgtat tctaggaaat agtatcggtg gactctatgc cttggtcttc
     6721 ttcttattaa ataccttttt ccatgaagcc ttttgggtga ccttggtagt tgttccaatc
     6781 tgcaccatgt taaccattat gacaaatgta gccatgaata acaaagcagg ggttattggt
     6841 ggtgtagcag ctatgttaat cattacccta tcaattccaa gtggtgagac aatttcgtac
     6901 gtgtttgtgc gtgtatcaga aacgtttatg ggagtttttg tcgcaattat cgtaaattac
     6961 gatattgatc gtattcgtct ctttttagag aaaaaagaaa aataatgtta cattttataa
     7021 cattatcaat tgacgtttgt ctttttttag actataatag acagaaagaa ggaaattgta
     7081 aatgaaggaa aaagaatttc gccgaaatat ggctgttttt cctatcggca gtgttatgaa
     7141 gttgaccgat ttatcggcgc gtcagattcg ttattatgaa gatcaagagt tgatcaagcc
     7201 cgatcgaaac gaaggaaatc gtcgcatgta ttccttgaat gacatggatc gtctgcttga
     7261 aatcaaagat tatatctctg aaggttataa tatcgctgcc attaagaaaa aatatgctga
     7321 acgtgaagcg aaatccaaga aagcggttag tcagactgaa gtacgtcgtg cacttcacaa
     7381 tgaactcctc caacaggggc gttttgcttc agtacagtca ccttttggtc gcggttaggc
     7441 aaccgcaagt agtcatagat taaggagaaa acttatgcca atcacagctg cagatattcg
     7501 tcgtgaagtc aaggaaaaaa atgttacctt tattcgtctt atgttctcag atattttggg
     7561 aaccatgaaa aacgtcgaaa ttcctgctac agatgaacag ttagataagg tcttgtcgaa
     7621 caaggttatg tttgatggat cttctattga aggttttgta cgtatcaatg agtcggatat
     7681 gtacttgtac ccggacttgg atacatggac agtcttccct tggggagatg aaaatggaag
     7741 tgttgcaggt ctgatctgtg atgtttatac aacagaaggt gaaccatttg cgggtgatcc
     7801 tcgtggtaat ttgaaacgag ctcttcgtca catggaagaa gttggattca aatccttcaa
     7861 ccttggtcca gagccagaat tcttcctatt taagttggat gaaaatgggg acccaacact
     7921 tgaagtgaat gacaagggtg gctactttga tttggcacct actgaccttg cggacaacac
     7981 acgtcgtgag attgtgaatg tcttgaccaa aatgggattt gaagtagaag cgagtcacca
     8041 cgaggttgcg gttggacagc atgagattga ctttaagtac gatgaagttc tccgtgcttg
     8101 tgataagatt caaatcttta aacttgttgt taaaaccatt gctcgcaaac acggacttta
     8161 cgcaacattt atggcgaagc caaaatttgg tattgctgga tcaggtatgc actgtaatat
     8221 gtccttgttt gatgcagaag gaaataacgc cttctttgat ccaaatgatc caaaaggaat
     8281 gcagttgtca gaaacagctt accatttcct aggcggtttg atcaagcatg cttacaacta
     8341 tactgccatc atgaacccaa cagttaactc atacaaacgt ttggttccag gttatgaagc
     8401 gcctgtttac attgcttggg ctggtcgtaa ccgttcgcca cttgtgcgcg tacctgcttc
     8461 acgtggtatg ggaactcgtc ttgagttgcg ttcagtggat ccaatggcga acccttacat
     8521 tgctatggct gttcttttgg aagttggttt gtatggtatt gaaaataaaa tcgaagcacc
     8581 agctcctatc gaagaaaata tctacatcat gacagcagaa gagcgcaagg aagctggtat
     8641 tacagacctt ccatcaactc ttcacaacgc tttgaaagct ttgacagaag atgaagtggt
     8701 taaagctgct ctcggagatc acatctacac tagcttcctt gaagccaaac gaatcgaatg
     8761 ggcaagttat gcaaccttcg tttcacaatg ggaaattgat aattatttag acctttacta
     8821 atactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt ctaagccatc
     8881 aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg aaaaatcctc
     8941 ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatta aggagtcact
     9001 atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact tcaaatcgaa
     9061 atctacaagt ttactaactt ttgcaagctt caaaattaca catctgtaaa tattttttcg
     9121 aaagatatat ttgaaaccat agtaaattga gactagaata gtacactaca tctgctaaaa
     9181 atttctagaa actaatttaa ctttcctaat cgatttgttt acatcttatt tcaatctact
     9241 ataattatct caataaatga tgatggcgac tgttttgttt gtgcttgtcg atttttgaat
     9301 cctgatcgag cggaagaata tttctgccga ggttgccaag gggaaaatac tgaagatatt
     9361 gaattttatg atgaacaatt acaggcagaa aaggtggagg ttttgaatat tcgattggaa
     9421 gtaaaaaatt gaattatcta caatctcatc aacaataaac ctatttcaac cccattatct
     9481 ataggcgtat ttttacgcct ttttatatac ttgaagcaca taagaaacat tatgggaagt
     9541 ttgctgatgg aagtactcaa gaaattgatg ttccttatga tattcctgat acttgggagt
     9601 gggtgaggat aaaatcaatt tattggaatt ttgggcaaaa taagccagag aaatccttta
     9661 ggtatataga tacgtctagt attgatagaa aaaagaacat aatcaactac aaaaatctac
     9721 aatatctttc acctgaacaa gcgccttccc gtgctagaaa attagtttcg cagaatagtg
     9781 tctta
//
LOCUS       DAVLUM010000070         9721 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLUM010000070 DAVLUM010000000
VERSION     DAVLUM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.070"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            232..327
                     /locus_tag="VYN42_001704"
                     /pseudo
     CDS             232..327
                     /locus_tag="VYN42_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(580..1200)
                     /locus_tag="VYN42_001705"
     CDS             complement(580..1200)
                     /locus_tag="VYN42_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1462751.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1200..1682)
                     /locus_tag="VYN42_001706"
     CDS             complement(1200..1682)
                     /locus_tag="VYN42_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1462752.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1682..2524)
                     /locus_tag="VYN42_001707"
     CDS             complement(1682..2524)
                     /locus_tag="VYN42_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1462753.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2619..3419)
                     /locus_tag="VYN42_001708"
     CDS             complement(2619..3419)
                     /locus_tag="VYN42_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1462754.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3563..4942
                     /gene="glmU"
                     /locus_tag="VYN42_001709"
     CDS             3563..4942
                     /gene="glmU"
                     /locus_tag="VYN42_001709"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1462755.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGVVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4952..5497
                     /locus_tag="VYN42_001710"
     CDS             4952..5497
                     /locus_tag="VYN42_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1462756.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5509..5823
                     /locus_tag="VYN42_001711"
     CDS             5509..5823
                     /locus_tag="VYN42_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1462757.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5840..6532
                     /locus_tag="VYN42_001712"
     CDS             5840..6532
                     /locus_tag="VYN42_001712"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1462758.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6609..7100
                     /gene="rocS"
                     /locus_tag="VYN42_001713"
     CDS             6609..7100
                     /gene="rocS"
                     /locus_tag="VYN42_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1462759.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7198..7788
                     /locus_tag="VYN42_001714"
     CDS             7198..7788
                     /locus_tag="VYN42_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1462760.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7797..9560
                     /locus_tag="VYN42_001715"
     CDS             7797..9560
                     /locus_tag="VYN42_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1462761.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         2995 a         1688 c         2078 g         2960 t
ORIGIN      
        1 gcagttcatt taacacctga taatatgcgt tttttgattt taaagacttt ttgaccagtc
       61 tcattttttt aacttgatac tcagtgcaaa gcaaagatta aactaggaag ctagctgtag
      121 gctgctcaaa gaacagcttt gaggttgtag ataaaacttg tgaggtaacc aacatatata
      181 atgtgaagct gacgtggttt gaatagattt taggagggta tgagtctgga agttttaatg
      241 gataatgcaa gattccatag aatgggtaag ctagagttct tatgtgaaga gtttgggcat
      301 aaacttttac cttttcctcc ctactcatct tagtatagaa aagtgaatct gaaatagtac
      361 ataactgctt ctaaaacatt cttataaatt gatttaaatt ctcaaatcat attattcagt
      421 tcttatttca ttttgctcta caatcctgtt gagaagacac gtgttcatat caaaaaggta
      481 ttggcaagtt gcaatacctt tttacgaggc tcttttatct tatttttgtt tcaactgact
      541 atatctccta tggttctagt tcagaaggct aggctataat tatgattgat aagaagtatc
      601 attccaagta ttgagagtga atgtttcaaa atcatgggtt tctataatgg tcaggctggc
      661 atttgctaga ccgccatctt tacgaagaag tggttcttta tagcctagga gagtacgaag
      721 actggcagta agattggcgc cgtgtccgac aattagaata cgctcagctg gactatcttt
      781 taatgatttg ataaattgga tggtccgctg agttgtacta tagagagatt cggctccgaa
      841 cattcgagtg tcaaattgag caagatttga acgaaaagcc tggatttgtt gcgggtaaat
      901 agcttccaag gttgcaattt tcaaaccttc taacttccca agttgccatt cacggagatt
      961 aggaacgatt tctaaagaac agggggtatg gagttgactt tggataatct cagcagattt
     1021 gaccgctcga ggtaaatcac ttgaataaat ctgatcaaaa ggaatttcct tgagatactg
     1081 gccaagtcgt tttagggttt caatggattc aggaagaaga ggagaatcac cgctagcacc
     1141 ttgaaaacga ccttcttggt tccagagggt acgaccgtgg cggacaaagt agagtttcat
     1201 tacttgatgt cctccaaaat atctacaaag tctgccttta caaagctagc caagtcttgt
     1261 ggcgcgacga taatgctgtg tccgacttcg cctgcagaga caatcatttg atccaaatct
     1321 agagcaattt tatcgataaa aatgggataa ttgtgtttct gacgaattcc gacaggatta
     1381 ttggctccat gaatgtaacc agttgttttt tctaagtcct tttgtggaat catgctcact
     1441 tttttattgc cagaaatttt agctagtttc ttttcagaca agtgctgagt gatagggaca
     1501 attccgataa tcggtcctgt cttgtctccc aaaagcgcca aggttttgaa aatctgatct
     1561 cgttcataac cttgaggaag ctctccttct agggcattga tttgaatccc ctgatgaggg
     1621 atagctgctt tagataggat ttgttccacc aatgtttttt tgattttaac tttttttgcc
     1681 attatttata tttatcctcc aattgactca tccaaatacc aagccagatt cccagcgcaa
     1741 agaagaaggc gatgatgaca taaccgacaa gtgaaagtcc tgtgtattgg atactttcag
     1801 cgtttcctgc atttggaatt aagatcaaaa gggtacttga taggacgata ccgatgatga
     1861 aatgatagac gcgtgagtgg tagttgttta aggcataatc catcaatttt gaaaaaacga
     1921 tgagagttgc acctgcacca attccaatcg gaaagaaggt tcccaagaga tcaaaagttt
     1981 taaaaccagt caacatagga gcatagagtc ccaaaatcaa aagtaaattc gatgggctga
     2041 ggccaggaac caagacgcca agggccaata gtgcgcctgc taggacgaag ttaagaaagc
     2101 tggcgcttaa ggttccaacg acaaaattta aggcatagag tcctaatcca gaaatgataa
     2161 aggttgtcca taaccaagct aaatcaatct tgtctcggtc agattctcga gttgattctt
     2221 tgaggaggct aggaactgta ccgataatag ctcccgcaaa gctccataat acaaagacct
     2281 gataattttc aagcaggtat tcaatcgggt aggaaaataa gccgattccc agaagcatac
     2341 cgatggcaac tggaataaag tacaaaacat tttctttaag gtctttaaag ggatgggcca
     2401 gaaagccaat cattcgttca tagattccta agattgctgc tagaacccct ccggaaattc
     2461 ccggtaggat aaatccaaga gcaattacaa tccctttaat aacgcgtgct aaccatgaga
     2521 gcatatattt cctccaacta tttctatttc aaaaaatcct tactatattg tatcacaatc
     2581 agacacaaaa agaaaaagca aatgataaac aaatgctttt aaggttttaa aaaaagtttt
     2641 cgaaaggttt cttctttatt ttttaaggga gagataacgt tgatatctaa atcgtggtca
     2701 aagccggcaa tttttccttt agatgtgtat tggtgaatat cataatctaa atcagtttta
     2761 ggactgctct ccaaaaatcc tgagtctgag ccgtaggacg gaatccaaac agaggtaaac
     2821 ttgcctgtat caatactgtg ttcttccatg aagtagacac caacgtagat gccgatgttt
     2881 ttagcaccta gtgatgctag ttttgctcga aagttttcga caccttcgtt catattagac
     2941 atggttttgt cttccacgtc aagccaatag taactagggc tgtaaggaga ggcagcattg
     3001 tagaaaactt cggcagcctt ttccatttct tgggcacttt ttccagctac ataagcgtag
     3061 acagcaactg ggacattccg cttttgaagt tcagtgatat gactcttata ggccttgtct
     3121 attccattga taaatgaagc atcattttct tttgtcgttt gagcaccact gtgaacacga
     3181 acaatagcac ctgaaatatt ttgtgagagg gcatcgtagt tgatttcctc aggacgctgc
     3241 cagccagaga ggtcaataat cggtttgtct aagtgtttca aagcctgtgc ttcaatctgt
     3301 gctatattgg attttgtttt aaacgattgg ttgtcattaa gtgggcgatt gatgattaaa
     3361 atgaacatca taatccccaa aaaactaaat aaaataagtg gatgaatttg ttttctcata
     3421 tcttataatt ctaccctaaa aatcaaaaaa aatcaaaaaa atgggttaag gaagagactt
     3481 tagagcattt tttcattcaa gagtgcggaa tgatttgaaa tatggtataa taaaagggaa
     3541 tttctacaga aaagagaaga ttatgtcaaa ttttgccatt attttagcag cgggtaaagg
     3601 gactcgcatg aaatctgatt tgccaaaagt tttgcacaag gttgcgggta tttctatgtt
     3661 ggaacatgtt ttccgtagtg tgggagctat ccaacctgaa aagacagtaa cagttgtagg
     3721 acacaaggca gaattggttg aggaggtctt ggctgaacag acagaatttg tgactcaatc
     3781 tgaacagttg ggaactggtc atgcagtgat gatgacagag cctatcttag aaggtttgtc
     3841 aggacacacc ttggtcattg caggagatac tcctttaatc actggtgaaa gcttgaaaaa
     3901 cttgattgat ttccatatca atcataaaaa tgtggccact atcttgactg ctgaaacgga
     3961 taatcctttt ggctatggac gaattgttcg taatgacaat gctgaggttc ttcgtattgt
     4021 tgagcagaag gatgctacag attttgaaaa gcaaatcaag gaaatcaaca ctggaacata
     4081 cgtctttgac aacgagcgtt tgtttgaggc tttgaaaaat atcaatacca ataacgctca
     4141 aggcgaatac tatattacag acgtcattgg tattttccgt gaaactggtg aaaaagttgg
     4201 cgcttatact ttgaaagatt ttgatgaaag tcttggggta aatgaccgtg tggcgcttgc
     4261 gacagctgag tcagttatgc gtcgtcgcat caatcataaa cacatggtca acggtgttag
     4321 ctttgtcaat ccagaagcaa cttatatcga tattgatgtt gagattgctc cggaagttca
     4381 aatcgaagcc aatgttacct tgaaagggca aacgaaaatt ggtgctgaga ctgttttgac
     4441 aaacggtact tatgtagtgg atagcactat cggagcagga gtggtcatta ccaattctat
     4501 gattgaggaa agtagtgttg cagacggtgt gacagtcggt ccttatgctc acattcgtcc
     4561 aaattcaagt ctgggtgccc aagttcatat tggtaacttt gttgaggtga aaggatcttc
     4621 aatcggtgag aataccaagg ctggtcattt gacttatatc ggaaactgtg aagtgggaag
     4681 caacgttaat ttcggtgctg gaactattac agtcaactat gacggcaaaa acaaatacaa
     4741 gacagtcatt ggagacaatg tctttgttgg ttcaaattca accattattg caccagtaga
     4801 acttggtgac aattccctcg ttggtgctgg ttcaactatt actaaagacg tgccagcaga
     4861 tgctattgct attggtcgcg gtcgtcagat caataaagac gaatatgcaa cacgtcttcc
     4921 tcatcatcct aagaaccagt aggagcctat catggagttt gaagaaaaaa cgcttagccg
     4981 aaaagaaatc tatcaaggac caatatttaa actggtccaa gatcaggttg aattaccaga
     5041 aggcaaggga actgcccgac gggatttgat tttccacaat ggggctgtct gtgttttagc
     5101 agtaacggat gaacaaaaac ttatcttggt caagcagtac cgcaaagcta tcgaggctgt
     5161 ctcttacgaa attccagccg gaaaattgga agtaggagaa aacacagccc ctgtggcagc
     5221 tgcccttcgt gaattagagg aagaaacagc ctatacaggg aaattagaac tcttgtacga
     5281 tttttattca gctattggct tttgtaatga gaagttaaaa ctatatttag caagcgattt
     5341 gacaaaagtg gaaaatccgc gtccgcagga tgaggatgaa accttggaag tccttgaagt
     5401 gagcttagaa gaagcgaaag aattaatcca atcaggtcat atctgtgatg ccaagacaat
     5461 tatggctgtt cagtattggg agttgcagaa aaaatagagg aggttagtat gggtaaatct
     5521 ttattaacgg atgaaatgat tgaaagagct aatagaggcg aaaaaatttc aggtcctcct
     5581 ttgctagatg ataatgagga aactaagatt ttaccaacct cttcttcccg ttttggttat
     5641 gccaatccta aggatcatgg ttttagccag gaaaccttga agattcaggt cgaaccatct
     5701 attcataaaa gccgtcgtat tgaaaatacc aagagaaatg tcttcaattc taagttgaat
     5761 aaaatcttat ttgcggtcat ctttctcttg attttgcttg ttttagcaat gaaacttttg
     5821 taatagaaaa ggaattgaaa tgaaaatagg aattattgct gctatgccag aagaactggc
     5881 ttatctggtc cagcatttag ataataccca ggagcaagtt gttttgggga atacctatca
     5941 tacaggaacc attgcttctc atgaagtcgt tcttgtagaa agtggaattg gtaaggtcat
     6001 gtctgctatg agtgtggcga ttttggctga tcatttccag gtggatgccc ttattaatac
     6061 gggttcagct ggggcagtag cagaaggtat cgctgttggg gatgtcgtga ttgctgacaa
     6121 attagcctat catgacgtgg atgtcacagc ttttggctat gcttatggac aaatggcgca
     6181 acaaccgctt tatttcgaat cagacaaaac ctttgttgct caaatccaag agagtttatc
     6241 tcaattggac caaaactggc atcttggttt gattgctaca ggagatagtt ttgttgcagg
     6301 aaatgacaag atagaagcga ttaagtccca tttcccagaa gttttagccg tggagatgga
     6361 gggggcagct attgctcaag cagcgcatgc cctcaatctc ccagtcttag tcatcagagc
     6421 tatgagtgac aatgccaacc atgaagcaaa catctttttt gatgagttta ttatcgaagc
     6481 tggacgtcgc tctgcccaag tcttgttgac ctttttgaag gctttagatt aagcggaaat
     6541 ttgacagttt ttctagctta tgataagatt taagtaaaga aaagctagaa aacgtttcag
     6601 aggatattat gagtattgaa atgaccgtca gtgagattgc agaggtctta ggattatctc
     6661 gccaagcaat caataaccgt gtcaaagaat taccagaaga agacacagat aaaaatgaca
     6721 aaggggtaac agttgttacc agaagtggct tgattaagct agaagaaatc tataaaaaaa
     6781 cgatttttga agatgagcct gtcagtgaag atgtcaaaca acgtgaactg atggagattc
     6841 tagtggatga gaagaatgca gaaattcttc gtctttatga acaattaaaa gccaaggatc
     6901 gtcagttatc agaaaaagac gagcagatgc gtatcaaaga ccgtcagatt gctgaaaaag
     6961 acaaacaatt agatcagcaa caacaattga cccttcaagc catgaaggat caagaaaatc
     7021 ttaagctaga gctggaccaa gcaaaagaag aagtccaatc cactaaaaaa ggcttttttg
     7081 ctcgtttatt tggaggataa tcaaggagct gtttaggtta aatgctaacc tgatggcttc
     7141 ttttgtttgt gaatagtata gttgattaga acagagacag tagaggagag gtacagaatg
     7201 gaacgattag aagattacat tgcttttgac ttagaattta atcagcacga aggacaaaca
     7261 cacttgattc aagtatcggc agtgcgtttt agagatggtc gggaaatcga tgcctatgat
     7321 tcctatgttc ataccagcgt ccctctaaaa agctttatca atggtttgac cgggattaca
     7381 gctgagacct taaaagatgc tcctccagtt gagaaagtct tagaagaatt ccaagagttt
     7441 gtgggttctt tgctgatgat aggctacaat gctgctaaaa gtgatttacc tattttagca
     7501 gagcatggtt tagactatag ccaacagtac aaggtggatt tgtatgatga agcttttgaa
     7561 cgtcggagtt cagatttaca tggtattgcc aatctcaaat tgcaaactgt tgcctcattt
     7621 cttggatttc aaggtcagtc tcataatagt ttagaggatg ctcggatgac ggcgcgtgtt
     7681 tacgaatcct tcttagagtc ggatcaagct agggaattgt tagagacaga aagtagctta
     7741 tcaaacaatc cttttggtgg cttggacttg tctcaattat ttgactagga gtgcctatga
     7801 aacctgaaaa acctaaaaaa ttgggtctta aacagattta cctcaatctt gataaaatcc
     7861 tctttctatt tttcttgatt tttatgatag tggagtattt gtgggtacca ttcaattcat
     7921 ggttggctag cttcttatta gatcagacag gttatctttt tatttcctat aacaatgtct
     7981 tagccatcct tactcattct ccattgatta gtctagcttt tttagccttg attgtaatta
     8041 accttctggt tgcttatttt caaataggac tcctctttat tggtgctcgt catctcctct
     8101 ataatgaaaa gcgaaggcta attgagtata tccgcaaggt tttccatgaa agttttggat
     8161 ttatgaaaaa gctaacttgc gctaaagcct tgtttatctt tttctatata gctatgctgt
     8221 ttccttttat acggaaaatg ctgaagattt attatcttaa taaaatcgtc attccagagt
     8281 ttatccaagc ttatttagaa gatagatatt ggatgtggtg gctgagcatc ctacttctat
     8341 ctcttatctt tctctatgtc tctgtcagat tgatgtttgc ccttccgaag attgtatatg
     8401 atcagctgac tgttcgagaa gcagtgatgt ttagcttgga gaaaaccaag aagagagtta
     8461 ctttttatgc ttggaattta ttttacatct tgctcaaagc acatttatta ttttatcttc
     8521 ctttgatccc tttattattg gctcaaactt tggtagatga tatcactcag agagagtctc
     8581 tgattcttgg tattttgaat tttgtcgtga ttaaaaatct ctattatatg gctctgactt
     8641 attttttggt taaatttgtt tcatttttga caggaaagga gctggatatg cttcctagga
     8701 gagaaaaaga tcacatcgtg cgatggggtg tcatgacttg tgccagtctt ttctttgcct
     8761 tagaaggtta tatttatctg gaggctccca tggttcatct acctcaactt atttctcacc
     8821 gaggggtttc caatgcaaat gggattcaaa atacagtaga gtccttggaa actacagcac
     8881 aactcaaacc agacttggtg gagacggacg tgcaggaaac aaaagatggg cagtttgtca
     8941 tgatgcatga tgctaacttg aaaaatctag caggtatcaa taaaagtcct caagacttaa
     9001 acttggagga gcttaaaggg attgatattt ttgaaaatgg ctaccagact aaaatttcaa
     9061 gctttgaaga ttatctcagt cgagccaacg aacttggtca aaaattacta attgaaatta
     9121 aaaccagtaa aaaagatagt ccagacatga tgaaccgctt tttagcccgt tatgctgcaa
     9181 agctcaagat ttatggacat caaatccagt ctttagacta ccatgttgtc gaaaaagtaa
     9241 gacagtatga tgccgaactg ccagtttatt tcatcatgcc ctacaattct gtctttccta
     9301 aaacaagagc gacaggatat actatggagt actcaacctt ggatgaatat tttgtaagca
     9361 aactatggac aacggatcag aaactttatg tctggactgt caatgattca gaagctatca
     9421 gcaaatctct tcacttagga gtagatggag tgattacaga tgatttggaa aaagttcagc
     9481 gggaaataga agtagcccaa gaagatccag aatatacgga tttgctcttg aaaaaagcat
     9541 tggaattctt tgaattttag taataaaaaa gaggaacggt tgttcctccc atgataggta
     9601 agtattcttg tgaatgcttg cttttttgtg gttgcaatcc gtttacgaga attgtttgta
     9661 ttgttcttgt ttcaatttac tttatagtgc tttgaagttg gaatgctaca ctataactta
     9721 t
//
LOCUS       DAVLUM010000071         9597 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLUM010000071 DAVLUM010000000
VERSION     DAVLUM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.071"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            330..938
                     /locus_tag="VYN42_001716"
     CDS             330..938
                     /locus_tag="VYN42_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462762.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(1025..1228)
                     /locus_tag="VYN42_001717"
     CDS             complement(1025..1228)
                     /locus_tag="VYN42_001717"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462763.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(1338..2042)
                     /locus_tag="VYN42_001718"
     CDS             complement(1338..2042)
                     /locus_tag="VYN42_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1462764.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(2112..3938)
                     /gene="glpO"
                     /locus_tag="VYN42_001719"
     CDS             complement(2112..3938)
                     /gene="glpO"
                     /locus_tag="VYN42_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1462765.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQFGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(3980..5488)
                     /gene="glpK"
                     /locus_tag="VYN42_001720"
     CDS             complement(3980..5488)
                     /gene="glpK"
                     /locus_tag="VYN42_001720"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1462766.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(5647..7074)
                     /locus_tag="VYN42_001721"
     CDS             complement(5647..7074)
                     /locus_tag="VYN42_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1462767.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QPPVYYLKNDLDMEDLAGIRQLLFT"
     gene            7239..8111
                     /gene="hslO"
                     /locus_tag="VYN42_001722"
     CDS             7239..8111
                     /gene="hslO"
                     /locus_tag="VYN42_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1462768.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            8098..9078
                     /gene="dusB"
                     /locus_tag="VYN42_001723"
     CDS             8098..9078
                     /gene="dusB"
                     /locus_tag="VYN42_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1462769.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(9308..>9597)
                     /locus_tag="VYN42_001724"
     CDS             complement(9308..>9597)
                     /locus_tag="VYN42_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1462770.1"
                     /translation="QYNGSWYYLNSNGAMVTGWLQNNGSWYYLNANGSMATDWVKDGD
                     TWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
BASE COUNT         2745 a         2193 c         1902 g         2757 t
ORIGIN      
        1 ttatttttta ttgtttttta ttgtagagca gacccaagcg aatgaacata ggttgtaaaa
       61 agcaaatgaa aaaactgcga ggataatagc ttctgtgtct aaataaccca tttcgagacc
      121 tcttttcaac aacaacaagc ctgtagtttc gataacgatc aaacataaaa atatataaaa
      181 aattttcgca ttaagcatat tgttaccgct ttctttttat ttggttttat tgtataataa
      241 aagttaaaaa aaatcaaaaa tacaaaggag tttccgttat gtctaagatg tttaaatgca
      301 tgtgtttgct agttatgtct gttttctgta tgtctagcat ttccccgtcg cttgttgttt
      361 ttgctgatga tagcttatcg gcaaactcta aagttgtatc tggtgaggct cagtttgaga
      421 atggctcatc agtgcggttc ggagatacgc aagtaaatat tttaagcgat gaagttcttg
      481 aggttgtcaa tccagatgga agtgtagaca ctattgaacg acgtgctgac ggcgtctata
      541 tcaatggggc attttatatg gcttatcaaa agaatgaaat cgacctaaat atatctttta
      601 gatcatacga tcctaatgtt tggaattacg tcaacacaat acatgggaat aaacaagcta
      661 acacattcgc taacttcatg actggtgctg gaatcagtta tatgattggt aggataggtg
      721 ctttattggg gggtccatgg ggtgcaataa ttggtggagc atattttggt atacaagctt
      781 atcagtctta cttggattca caaagcccat atccatacta cataacaagt acttatatcc
      841 atgttgctca aagaaaatgg aagtttatca ctgaatacta tagaaactca aactatactg
      901 ggtatgtaaa aaccgtaaca acctacgtga atttctaaaa tataaaccct gcctagatat
      961 aaaggcaggg tttatatttt agttaattgc tcaagtaatt tgtaagcata atacttgcga
     1021 aactctattt gttcaagcgg ttcaaaagct cttgtttttt atcctcaagc tcagctctcc
     1081 tttgctcgat ttcttcacgt ttttgggcga tttctgcttg cgcctcggga gtttccaaag
     1141 tgccttgtga cttgtgaaat tctactagca tatcaacgat ttttgggtct aattcgttga
     1201 cataatcagg atttgaccat ttcggcacgt tgcttgcagg tgcttgatat gatgcgtttt
     1261 attatgagaa gatttacttc attttttgct gaaattgggc tcttgcccaa gctctatcaa
     1321 cataattgtt ttctagatta gaaaagtgag aatacaagca cggccaaggc tgctccgata
     1381 acagggccta caacaggaat ccaagcgtaa gaccagtctc cgtctccctt gtttggaatt
     1441 ggcaagatgc tgtgcatgat acgaggtcca aggtcacgag ctgggttcaa ggcataacct
     1501 gttgtcccac ctagtgatag accgataccg acaatcaaag ttcccactgc aaaggttccg
     1561 atacctgcct gaaaatcgta aagacccaaa gcaaagattg tcaacaccaa aacaaaggtt
     1621 ccaaggattt cgctaatcaa gtttgataca gtatccttga tggctggtcc agtactgaag
     1681 gttgccagga tattgcctgc attttcttct gcctcatagt gaggtttgaa ttgcaaccaa
     1741 accaaaatct gacccagcat ggcccctgcg aactgggcta agatataagg caaaacggaa
     1801 gcccaaggca aaccaccttt taaggccaca ccgatggtca cagctgggtt taaatgagct
     1861 ggactgagct tgccagatac aaagactgca accgcaactg caatccccca acccatagta
     1921 atcacaatcc aacctgagct attgctcttg gttttaggaa gaaccacacc tgcaacaaca
     1981 ccatttccta gaagaatcag gattaaagtc cctagaaatt ctccaaataa ttcattcatc
     2041 atctttctgt ctccattaaa aagaagggac gggcgacaag gaatgctgcc ctccacctct
     2101 tttatttttt cttaattttt taattctgct aaatcgttgt tagcgagagc tgcttcgaca
     2161 tcagcacggt aagttgcttt ttcttcttct gtccagtcat agaatcgtcc catttcatcc
     2221 aaaattggct caacgatact atccaagcta tcacgcataa agagcatgtg attggtacga
     2281 cgaagaagga agtcaactgg gctaagagtc aactcattgc gcattgcata gtgaagggac
     2341 aaggtgtctg ccaagctaag acctggcgct tgttccaagc tgtgagcaag tgcaaagacc
     2401 ttcggtgcat ttgaaccgta aagatttgct aggtaatgag cttccttgct atccaaacca
     2461 cgtgatactc caaattgcgc aaaggcttcg atttctgaat ccacatttgc tgggttcaat
     2521 tctccacctg aaacagggta agttttagaa ttgatcaatt taaagctacg gtcaaattct
     2581 gctttgagga tgtcaaccac gcgctccata gctccttcag ccatcttacg gtagtctgtg
     2641 attttaccgc cagcaagagt caaaagacca ttgtcatcac ggtccaagct agacccacga
     2701 gaaactgcag atggatccaa atatttctca gatgtgctac tttcaagctt gctgacagca
     2761 gactcaacat cttcacgtgt tttttctttg gagagataag attcaacagt cgcaatcaag
     2821 ttgtcaaagc tttcatcact gatggtaccg ttatttccac cattatagtc agaggcactg
     2881 ttccctgcaa tcaatggacg aagacctgcc cagctgcttt cgatatcatc aatggtgatg
     2941 ttggattctg gaaagcggtt gttgacaatg ccaagtagat aatctacatc ttcttgagtt
     3001 acttttggat gctccaaatc acctgtgtag tctgtatcag ttgtaccaaa gtaagtcttg
     3061 ttttcacgtg ggagaacaaa gaccatacga ccgtcaccca aacctgtgtc aaagtaaact
     3121 ggctgtgaaa ccttgatttt gcttgaatcc actaccaagt gaactccctt agttgggcgc
     3181 atttgtgaga attgcgttcc cttattagac aaattacgta ctttatcact ccaaggacct
     3241 gttgtattaa taaccagacg ggccttgatt tcaaatactt ggtctgtcaa gagatcacga
     3301 gctacaacac ctgtaatctt gccactttcg tcaaagagga agccttctgc cttcacgtgg
     3361 ttggcaatga gggcaccgtc ttggttggca cgtttgatgt tttcaatcac gagacgcgca
     3421 tcgttgttac ggaagtcaag atacactcca cctcctacca agccttcctt cttcaagttt
     3481 ggctggcgtt ccaagacttg atccttgctc aaaaccttgt tcgcagttgg tgtgttgctc
     3541 acacctgcta aaaggtcgta caagtccatg gctactttaa gacggaagag gctaaaggtt
     3601 gctccatctt catcgtaaac tggtaagagc attggatctg gttttggaat gtgtggagcg
     3661 atttgttgaa ccactgcacg ttcagaaacc gtatctgaga ccacctctac gtcaaattgt
     3721 ttgaggtaac gaagtcctcc gtgaaccaat tttgttgaac gactagatgt tccttctgca
     3781 aagtcttgca tttcaatcaa accagtctca agaccgctag ctgccgcctg caaggctaca
     3841 ccagctcctg tgattcctcc accgataatc aagaggtcca gggtgcgttc ctgcattttt
     3901 ttaattgaca attcacgtgt tttctttgaa aattccatat ttacacactt tctaaataaa
     3961 tcgctttatt ctgccagtat tagtcgtcta cttccgcaaa gacttgagtt gctttcacag
     4021 ccttcttcca gcccttgtag agttgttcct tgcgagattc attcatagat ggctcaaaga
     4081 gttctcctgt ctcgttcaag agtttcaact cgtccaagtc tttccagtac cctactgaca
     4141 aacctgctag gaaggccgct cctagagctg ttgtttccaa gtttttagca cgtgcaatgt
     4201 caatgcctaa aatatccgcc tggaattgca tgaggaagtt gttcatggct gcaccaccat
     4261 ccaccttcag tacttgaatg gcggtctgag tatccacttg catggtgtcg atgatgtcac
     4321 gcacttgata agcaatagat tgcaaagtcg ccttgataaa gtcttctttg cttgttccac
     4381 gagtcaaacc aaagacggaa ccacgagcat tttggttcca gtatggagcg cctagacctg
     4441 taaaggctgg aacgacataa acttcatcgt tgttgtgaga atcacgagcg tatttttcag
     4501 attctggtga attttcaacc atgcgaagac cgtcacgaag ccactgaata gcacttcctg
     4561 cgatgaagat agaaccttcc aaggcataat aaaccttacc gttgattccg taaccaatgg
     4621 ttgtcaagag gttgttttca gacaactgca tctcttcccc agtattcatg atgatgaaag
     4681 agcctgttcc ataagtattc ttaaccatac ctggctcaaa agccaactgt ccaaagaggg
     4741 ctgcttgttg gtccccagcc atacctgaga ttggcacctc tccaccgtag aaatggaatg
     4801 gagctgtctt gccgtagatt tcggagttag aacgaacttc tggaagtata gccttcggaa
     4861 tgttaaggat ttccaaaatt tcatcatccc atttgagttc tttaatgtta taaagcatgg
     4921 tacgagctgc atttgagtag tcagtcacgt gagccgcacc gtcagtcaat ttccaaacca
     4981 accaagtatc gatagtacca aagagcaatt cccctttttc tgctcgctct tgagcgcctt
     5041 ctacatgatc caaaatccaa cgaaccttgg tagcagagaa gtaagcatca ataatcaaac
     5101 cagtcttttc atggaatttt tccacataac cttggctttt tagttgctca gccaaaggtg
     5161 ctgtctggcg tgactgccaa acgatagcat tgtagatagg aagtcctgtt ttcttatccc
     5221 agacaaccgt tgtttcacgt tggttggtaa tcccgattgc ctcgatttga tttggcttga
     5281 caccactttc gatgaaagca cccgcaataa ctgactgaac agagttccaa atttcattgg
     5341 cattgtgctc aacccaacct gcctgaggga aaatctgggt aaactctttt tgactcgagc
     5401 taaccttttc cccttttttg ttgaaaatga tggcacgaga acttgtagtt ccctggtcaa
     5461 tggccatgat gtatttttct tgtgacatat actgtcctcc tgataaagat cttgaggtgt
     5521 ttcctcttta cacttactag tatacaaaat aaagcgcttt cttgtttatc aacttttttt
     5581 aatttttaaa aaaatgtgag gagattgtgt gaatttcaca aaaaagacct ggattaacca
     5641 agccttttaa gtgaataata actgacgaat ccctgccaaa tcttccatat ccaagtcatt
     5701 ttttaaataa taaactgggg gctgttcctt cttatgaatc gggttattgg taaccagcaa
     5761 atcataatgc cgactagggt cataagcttc aatggtaata aaacgattgt attccaaata
     5821 ccgtttcaaa atggctgcca tccttgaaaa gacaagaaaa ccagatgtca aatccagacc
     5881 aatccgcata tgctggccac cgttttcagc catatattcg attaactgga gccattccca
     5941 gagaatcttc ttatctaaat ctgtcccctg ttgaaaagta ggtagagcat gaaaaatctc
     6001 ctctgctgtc tctttaaaat catgttccat cagtaaatat ggatgacgat tctctaactg
     6061 gtacttgtag cgatcctgta aaatatagcc cttatagaga tagacttgag cacaaagctg
     6121 actgagttca taggtgacat ggtcctctgt ataatccccc aatagttcct ccttcttcat
     6181 ttcttgaatc aattgcgtca gtaaatctgc caactgccct ccaaaaccaa gaatatactc
     6241 catagtatga agaggaagaa tgcgatgaga taggagaaaa gagaagaata tcatcatctc
     6301 accatcctca actcctagtg gaatatgttg cccagcaaaa aaggacggaa cctttctcag
     6361 caaacgaagg tagaaaatat tgtcaaaata ccctcgcatt ttctcttcta tgacttgaaa
     6421 ctgacaagca ttgacccgaa gacgttgttg actgatgtga gcccagagaa ccaagtccaa
     6481 tttctgcccc acagacaaac ttgcaccgca gatttcctct aaattggcaa tctcctgttt
     6541 tctctctggt ttctgcatgt gaccttccca ttcctgactc gaccagacct ttcggaaaag
     6601 acagaaatag aaatagcgaa tctgatgctc tggacctcgc caacgtccat tttggatgga
     6661 taaatcaaat tctgacaaaa tctgatttaa accagccaag tgacgaccaa gcgtagcctc
     6721 gctaatcacc aattcttgag ccagctgatg ggctaaaaac tgttggtggt agagaagata
     6781 aaccaaaatc tggtatttaa cagcactctc caaaaacaag ctccgaatat ctctcccctt
     6841 ggtagctgca ccgatagaca gacgcagatt ttcatcttct gagtgaatag ccagctctaa
     6901 gccactatcc aaagccttgt cattgagcag ggtgacatat ttggttaggg ttgcttttga
     6961 aaatcctgtt tcttccatta cagccttgac ggtcgtctga gactcttgta atagaaagga
     7021 aaggattgaa aattgaccac actcggcttt ctccatcaaa tctcctaaat acatttgtta
     7081 cccctttcat tttctacctt aagcatagca taaatcttac aaatgctaaa ataatctgtt
     7141 tctcttttta ttttcatgct gatttcctgg tccattatcc tgaaaatcag taaacacacg
     7201 gctccccctt tgggcatttt tatgctaaaa tagtagctat ggataaaatt attaaaacta
     7261 tatcagaaag cggagccttt cgtgcttttg tccttgatag cacggaaacc gtccgcactg
     7321 ctcaagaaaa acatcaaacc caagctagct caactgtagc gcttggtcga actcttatcg
     7381 ccagccagat tctcgcagcc aatgaaaaag gaaataccaa acttacagtt aaggtgttgg
     7441 gctctagctc tctaggtgct attatcaccg tcgctgatac caaggggaac gtcaaaggct
     7501 atgttcaaaa tcctggtgtt gacatcaaaa agactgcgac tggtgaagtc ctagtcggac
     7561 cttttgttgg aaatggtcaa ttcctcgtta tcacagacta cggtgctgga aatccttaca
     7621 actctataac tcccctcatc tctggagaaa tcggtgaaga ccttgccttt taccttactg
     7681 aaagccaaca aacgccttca gcggtcggcc tcaatgtcct tttggacgag gaagacaagg
     7741 tcaaggttgc aggtggtttc ctagttcaag tcttgccagg agccaagaaa gaagagattg
     7801 ctcgctttga aaaacgcatc caagaaatgc cagctatctc tactcttctc gaaagcgacg
     7861 accatatcga agccctcctc aaggctatct acggggacga agcctacaag cgtctttctg
     7921 aagaagaaat ccgtttccaa tgtgactgta gccatgaacg ctttatgaac gctcttgcca
     7981 gccttccaag ctcagactta caggaaatga aagaggaaga ccacggggca gaaatcactt
     8041 gtcaattctg ccaaactact tacaactttg atgaaaagga cctggaggaa ctcattcgtg
     8101 acaaatctta atacaccttt tatgattggc aatgttgaga ttcccaatcg taccgtttta
     8161 gcgcctatgg ctggcgtgac caactcagcc tttcgtacca tcgcaaaaga gctcggagct
     8221 ggactcgttg taatggaaat ggtctctgac aagggaatcc aatacaacaa cgaaaaaacc
     8281 ctgcacatgc ttcatatcga tgagggcgaa aaccctgtct ctatccaact ttttggtagc
     8341 gatgaagaca gcctagcacg cgcagcagaa ttcatccaag aaaacaccaa gaccgatatc
     8401 gtcgatatca acatgggctg ccctgtcaac aaaatcgtga agaacgaagc tggtgctatg
     8461 tggctcaagg atcctgacaa gatctactct atcatcaaca aggtccagtc tgtccttgat
     8521 atcccactta ctgtcaaaat gcgtaccggc tgggcggacc catctctggc agtagaaaat
     8581 gccctcgctg ctgaagctgc aggtgtttct gccctcgcca tgcatggccg tacccgtgaa
     8641 caaatgtata ctggccacgc agaccttgag accctttaca aggttgccca agctctaacc
     8701 aagattccat tcatcgccaa cggtgatatc cgtactgtcc aagaagccaa gcaacgcatc
     8761 gaagaagttg gtgctgacgc agtcatgatt ggccgagctg ccatgggaaa tccttacctc
     8821 ttcaaccaaa tcaaccatta ctttgaaaca ggagaaatcc tacctgattt gacctttgaa
     8881 gacaagatga agatcgccta cgaacacttg aaacgattga ttaacctcaa aggagaaaac
     8941 gtcgcagttc gtgaattccg cggcctcgct cctcactacc tccgtggaac atctggcgct
     9001 gccaaactcc gtggagccat ttcgcaagct agcaccctag cagagattga agccctcttg
     9061 caattggaga aggcttaata gtttaaaacc cgtaactctc ttaaagagtc tcttgaatgc
     9121 cgccattctt tcctcatcaa aaaaactccg tagtctctag cgctataaat ccggctagag
     9181 attacagagt tattttttaa tctaaacttc ctacaagggt atattatcta ctgaaaggat
     9241 atggtatttg tagggaatac tttaaagagt tcttacagga agtcagtatt aactagttat
     9301 attaagttta gtttacccat tcaccattgg cattgactct atagctatct acagttgtgt
     9361 tgactgcaag ggcacctgag ccattgacat agtaccattt atctgatact ttgaaccatt
     9421 ggcttgcttt catagcacct gatgcttcaa gatagtacca ggtatctcca tctttcaccc
     9481 aatctgttgc cattgaaccg ttagcgttta ggtagtacca tgagccattg ttttggagcc
     9541 atcctgttac catagcacca ttgctgttga ggtagtacca tgaaccattg tattgga
//
LOCUS       DAVLUM010000072         9527 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLUM010000072 DAVLUM010000000
VERSION     DAVLUM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.072"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..319)
                     /locus_tag="VYN42_001725"
     CDS             complement(<1..319)
                     /locus_tag="VYN42_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1462771.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGMIWTVV
                     VFLM"
     gene            complement(330..2153)
                     /gene="dnaK"
                     /locus_tag="VYN42_001726"
     CDS             complement(330..2153)
                     /gene="dnaK"
                     /locus_tag="VYN42_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1462772.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(2633..3157)
                     /gene="grpE"
                     /locus_tag="VYN42_001727"
     CDS             complement(2633..3157)
                     /gene="grpE"
                     /locus_tag="VYN42_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1462773.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(3184..4218)
                     /gene="hrcA"
                     /locus_tag="VYN42_001728"
     CDS             complement(3184..4218)
                     /gene="hrcA"
                     /locus_tag="VYN42_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1462774.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKVLQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(4382..4891)
                     /locus_tag="VYN42_001729"
     CDS             complement(4382..4891)
                     /locus_tag="VYN42_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1462775.1"
                     /translation="MNSRVEFRIFTILDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQEFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREELSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            5498..7831
                     /locus_tag="VYN42_001730"
     CDS             5498..7831
                     /locus_tag="VYN42_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1462776.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            7844..9307
                     /locus_tag="VYN42_001731"
     CDS             7844..9307
                     /locus_tag="VYN42_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1462777.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            9307..>9527
                     /locus_tag="VYN42_001732"
     CDS             9307..>9527
                     /locus_tag="VYN42_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEV1462778.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADG"
BASE COUNT         2948 a         1785 c         1867 g         2927 t
ORIGIN      
        1 tcataagaaa tacaactact gtccaaatca taccaattat gaacggtatt acaaatttat
       61 atgtttgtat ttctaatgat atcatagctg ataccagcgc cgatacaaat gcagacaaca
      121 atactgaggt aacaaaattc cttaccgctt catcattttt gatacaacta tcatgttcag
      181 ctaatataat ttctctatat ctagctaaat attctattgg aatattatca ataaaatctt
      241 ttgatgttct atagttatca gcttgattac aaaaatcatt ataaactttt cgtgtatttt
      301 ttagatactc ttcatccaat acactcgtct tacttttccg taaactctcc gtctacgacg
      361 tcatcgcctg cgtttcctgt tgcttgtgcg ccttctgctc cttcttgagc ttgttgcgct
      421 gctgcggctt gttcgtagag tttaacagca agtccttgag ctttttcgtt caatgcttca
      481 agtttcgctt tcatgtcgtc caagttgttg tcttcttgag ctttcttaag gtcatcaagg
      541 gcagcttggg cagcgtcacg ttctgcgtcg aagcctttac cttcagtttc cttgattgtc
      601 ttttcagtcg caaagattgc ttggtctact tcattacgaa ggtctacttc ttctttacgt
      661 ttcttatcgg cttcagcgtt tgcttctgca tctttcatca tgcggtcgat ttcttcgtca
      721 gtcaaacctg agttcgattg gatgacaata gtttgttctt tttgagttcc aaggtctttg
      781 gccttaacag acacgatacc gttcttgtcg atgtcaaatg ttacttcgat ttgaggaatt
      841 ccacgaggtg cagctgggat atcagtcaat tggaagcgtc caagagtctt gttatctgct
      901 gccattgggc gttcaccttg aagaacgtgg atatcaacgg ctggttggtt gtctgctgct
      961 gttgagaaga cttgtgattt agatgttggg attgtagtgt tgcgatcgat aagttttgta
     1021 aatactccac ccattgtttc gataccaagt gacaatggcg ttacatcaag aaggacaacg
     1081 tccttgacat caccagtaat cacaccacct tggatagccg cacccatagc aactacttca
     1141 tcagggttta ctgatttgtt tggttcttta ccagtttcag ctttaacagc ttcaacaacg
     1201 gcagggatac gagttgaacc accaacaagg ataacttcgt cgatttctga caagctcaaa
     1261 cctgcatctg aaagggcttg acgaactgga acttttgtac gttcaacaag gtcacgagtc
     1321 aaatcatcaa atttcgcacg agtcaaagtc atttccaagt gaagaggtcc agcctcacct
     1381 gcagtgataa atggcaagct gatttgtgtt gaagttacac cagaaaggtc tttcttcgct
     1441 ttttcagccg catctttcaa acgttgcatt gccatcttgt cagtagacaa gtcgataccg
     1501 ttttctttct tgaattctgc taccaagtgg tcaatgattt tttggtcaaa gtcgtcacca
     1561 ccaagtttgt tgtcccctgc agttgacaat acgtcgaaga caccgtcacc caattcaagg
     1621 atagagacgt cgaatgtacc accaccaagg tcaaatacca agattttttc ttctttatca
     1681 gtcttgtcca aaccataagc aagagctgct gcagttggtt cgttaacaat acgttctact
     1741 tcaagaccag caattttacc agcgtctttt gttgcttgac gttgagcgtc gttgaagtaa
     1801 gccggaactg tgataacagc tttggttact ttctcaccaa ggtagtcttc agcgtagcct
     1861 ttcaagtatt gaaggatcat agctgagatt tcttgtggag tgtattcttt tccatttgca
     1921 gaaacttttt cagaagttcc catcttagat ttgatagaga taactgtatc tgggtttgtg
     1981 actgcttgac gttttgcagc atcaccaacg atgatttctc cgtttttgaa tgagactaca
     2041 gatggagttg tgcggtttcc ttctgggttt gcgatgattt tgctttcagt tccttcaaga
     2101 actgcaactg ctgagtttgt tgtacctaag tcaataccga taattttaga catgtgtttt
     2161 tctccttgtt agttaatttt ctatttttct ttttgatact cttcttaagt ggcgacgccg
     2221 tcagagcttg acttcgtcaa tctctttgac taaactttga gcctaaggtc tcaaaatttg
     2281 cgcaaatagc gccacggcga agagtatcgt gtttggttcg cttcgctcac tattacaaag
     2341 ccaaacatat tttatctttc ttcatagttt attgtcgttt cggacaagtt ttctattatg
     2401 taaattgcga cacgaagagt cgaaatcgat tttatttcga cgacgagtta gtaaggaagc
     2461 taggcaaacg ccatagcgat tgccgttttc tgacgagttg ctttagctac cgtcagaatt
     2521 gccgaatcga acacgcccta agctctgagt aaaaaagata gattttcttg tgttcatcga
     2581 acacttcgtt aatctcctat ttttactgcg agctttttac gggctttgta tcttagttat
     2641 acaccactac cattgctggg cgtaggatgc ggtcatggag tttgtagcct ttttgaaaga
     2701 cttgagcgat ggtatctact gggtgttcat cgtctgctgg gagagtttgg atggccatat
     2761 ggtagttatg gtcaaattcg ccatctgctg cgatttcttc aattccttct tctttcaaag
     2821 cgtgaatcaa gctttcttgc accatcccca agcccttctt cacatcatct gtcaaacctt
     2881 caactgcaag tgcacgctca aggttgtcaa gagatggtaa gattgctttt gccaagtcct
     2941 ggctacgata acgttgcaag ttttgacgtt cttcattggc acggcgttgg atattttgca
     3001 tttctgcatg agcgcgaaga tatttgtttt cgaactcatc tgcacgttca tttgccaagt
     3061 ccaactcaga cttttcagga gttgtttctt cagctgtttc cacaacttcc tcttcttgaa
     3121 cttcttctac ttcttcattt tttatatctt gggccatgtt cgcctccttt aatgatttca
     3181 atcttaatgt acttcgtaat gattactgct gaggtagcgg taaaaatctg tcaacttcat
     3241 ggtcaaaaca cggttgacca cattgatttg attgattagc tgttggtaat ccagattaac
     3301 tggaccgata atggctagaa ttccaactcc ccgataagga atgaggaact tactactaat
     3361 caccgctagg tcagctaaac aggactcttg accgtctgca atacgaacat tttgcatctg
     3421 atcctcacgc aacccctcac gaatctccaa ggccaccttt tgcggttggt caaagaactg
     3481 ataggctgct agattggcaa aattcaagag attgaccttg cccgccatca caatgttttc
     3541 gttgaacatt tccttaaaga tgtgttcaaa gagatcgatg acattatccg ttgttgtaaa
     3601 gtaacgctgg ataatctgcg gaatctccgt ccgaatcttg tagtgaatat ctaaaacggt
     3661 gtgaccgagg aaacgttcct gaatgatgct cttcagtttc agcaaatcct cctgcaagaa
     3721 gttccttgga atcagaaact gactagtaac cgttcgcgac tcgtctaggg taaataccgc
     3781 caaggctgta tgttgcccca aaacaacgat atcaaaggct gtcaaacgtt gcctgctcgg
     3841 ctcaacatcc agtgccacta ccgtacagcc actcaggtct gttagcaagt tagcagcctc
     3901 ttgcagaata tcctccaatt tgaagaattc ctgatcaaag gctttgacaa tctcatatac
     3961 ctcattttca gccagccggt gaaaatccag tgagtgtttc acatagtact gaaaaccagc
     4021 aacacttggc atccgaccgc ttgaagtatg agccttctca agcaaccctt gtttttctag
     4081 ttccgccatg tcattacgaa tggttgcact gctagagtta atagactctt gcaagacttt
     4141 tgatccgaca ggttcgtgcg ttttggtaaa gatgtcaata atcagattta aaatatcctg
     4201 ctgacgctct gtaaccatct catcactcct ctctgtctga tcaattagca ctcaatgcat
     4261 ccaagtgcta acttatgatt ctattataca cccttagaag agaatgtcaa gacaaaaact
     4321 caaaaaatta gcactctttt atcaagagtg ctaaaaatca atctgaagac ctagaacctt
     4381 gctattcatc tactcggtat ttccttttta gtctgaaata accatgaatt agataagaaa
     4441 tcagaaaagc atataaaaca aaaataagaa agaaagacat agaaagttcc tctctaaaca
     4501 aactcataca aacaacaaga ccacctaaga aagtagctgt acaggaacga agtctagatc
     4561 gcataacttc ccatttgagc cccttactca tatagacttg atcctctgga agtaaatcag
     4621 aagacgattt acgaagaatc gaacaagaac ctgctcctat caattcccaa cctctatctc
     4681 taaattcttg cagttcatgc ttatattttt taagaaatct agaatcatag atacggtaga
     4741 tgacatcgtc tggttgacat tggtcaaaat agaacaaacc aaaacgactc gttctatacc
     4801 tccaaccttt caaatgcatc tcatgtaaat attcttcttc cttgtccaaa tcaagaatgg
     4861 tgaaaatccg aaattctact ctgctattca ttgtcttacc ccaaaattag aaaacatgcc
     4921 tggcgttatt tattagataa ttctttccac ttttgactca atctccaaaa aatataagaa
     4981 atctgaatcg caaaaactat caataaaacc caatctatta tgaaaatcaa aaatactcct
     5041 caactgaaag aactacctcc agtgacaaac tttgagaaaa ccggtagtag agctaaaaag
     5101 agaagcaaaa taggaagcat ccgcattgtt aaaatccgtt tggcataaaa aatctttatt
     5161 taaacgaaaa tattatggca aaatttacgc cagtttttga acggctgatg tagatatttt
     5221 atactttcaa aatgtttaaa tgtgattatt tatttttgaa aaatagctca ccagcccgac
     5281 tgaaagtgct tatagaatga taataagtcg cctgccgaaa acagcgaaaa atagcggtgt
     5341 tatgcggaga taatctgacg cgatgcgaaa gtatattgca tacttatttt caacaattta
     5401 gcagagtatt tttataagtg tgatataata gaagtataat ttgttctgat agtttatttt
     5461 atggagaagt agatttttag aatgcggagg gttcaatatg gttgagttta taaagtctaa
     5521 gaaagaaatg agtgaggagg atattaaagc aaatttcatc actcctgcta ttgtatccaa
     5581 aggatggaaa aatggtgagc atatcgctta cgaagaatac ttcactgatg gtcgaattga
     5641 agttagagga gataaggctc gtcgtaaaga aggaaaaaaa tcagactatt cactgtatta
     5701 ccaatttgga actcgaattg caattgttga ggcaaaggat aataaacaca gcgttcgagc
     5761 aggattacaa caagctattg aatatggaga gattttagat gttccatttg tttattcttc
     5821 gaatggtgat ggctttattg aacacgaccg tatcacgaga gaagaacgtg agctggagtt
     5881 agacgaattc cctactcgtg aagaattatt ttctcgtatg acgaaggaaa aaggattgac
     5941 gtacgaaatt acagaagcta tctcaactcc atactataca gacgccttct caatgaaaac
     6001 gccacgctat tatcagcaaa tagctatcaa ccgtactatt gaaacagttg ccagaggaca
     6061 aaaacgagta atgtttgtga tggcaacagg aacggggaaa acgttcatgg cttttcaaat
     6121 tattcatcgc cttcgaaaag ctggtttggc taaacgagtt ttattcttag cagatagaaa
     6181 catcttagta gaccaaacga tggctgaaga ctttaggcca ttcgaaaagg taatgacgaa
     6241 aattacacca aaacttttga ctgctcctga aaaattaaat tcttttgaaa tttatctagg
     6301 gctttatcag caactaactg gtgaagatgg aactgaaaca cattatcaaa aatttgacaa
     6361 agacttcttt gatttaatcg taattgatga agcgcaccgt ggttcagcta aggaagacag
     6421 taactggcgt aaggtgattg attatttcag ttctgcgaca cagattggga tgaccgctac
     6481 tcctaaagaa accaagaatg cttccaatac ggaatacttt ggtgagccaa tctatactta
     6541 tagtttaaaa cagggaatcg aggatggttt tttggctcca tatcgtgtta tgagggttaa
     6601 tttagatgtg gatgtggatg gttatcgtcc agaaactgga aaagttgata ctaacggaca
     6661 attaatagaa gataggtact acggcaggaa agattttgat aaaaccattg tcattgatga
     6721 tagaacgcaa agagttgcca agtttgtttc tgattatatg aagcaaagca atgcacgatt
     6781 tgataaaaca attgtttttt gtgttgatat tgaccatgcc gagcgaatgc gtgctgcact
     6841 tgtaaaagag aatctagact tagtccaaga agactatcgt tatgtcatgc aagtaactgg
     6901 tgacaacgct gaaggaaaag ctcaactgga taactttatg gatgtcaatt ctaattttcc
     6961 cgctattgta acaacgtcta aattattaac gacaggagtt aatgctaaaa catgtcgttt
     7021 gattgtttta gactctaata tccaatccat gactgaattt aaacaaatta ttggtcgtgg
     7081 cacacgtctt tatcctcaaa aggggaaaga attttttacg attattgatt ttcgaaatgt
     7141 taccaatttg tttgctgacc ctgattttga tggtgagcca gtgaaggtgc tggaaacagg
     7201 tgcgaaaaca gtcagtggtt ctacgcccgg tttcgtagat gaggaaggtg acccagtaga
     7261 aaaatatatc gttacagaca agcaggttac cattcttaat tctactgttc aagtattgga
     7321 tgaaaacggg aaactgatta ccgaaagcct gaccgactac actcggaaga atatcttagg
     7381 tagctacgcc actttgaacg attttatcac agtttggcat acggcggata aaaagaagct
     7441 tatcttagac gaactttata aaaaaggagt ttatctagat gctattcgag agtcggaggg
     7501 aatatcagaa caagaaatcg atgattttga tttactccta aaacttgcct atggtcaaaa
     7561 agaattaacc aaaacggaac gtatcaataa actcaaacaa agcggatatt tatataaata
     7621 tagtgaggaa gcgcgtgctg ttttggaaat tttactgaac aaatacatgg ataaaggtat
     7681 tggagaactc gaaagcattg aaacattaaa acttccagaa tttcagatat atggtggaac
     7741 cttcaaaatc atcaatactt attttggaga taaaaaacga tatttacaag caattaaaga
     7801 attggagcaa gagctattta cagtagctta atgaaaggaa agtatgtcaa ttacatcatt
     7861 tgtaaaaaga attcaagata tcactcgaaa cgatgctggt gttaatggtg atgctcaacg
     7921 tattgagcaa atgtcttggt tattattctt aaaaatttat gatagccgtg aaatggtttg
     7981 ggaattagaa gaagacgagt atgagtcaat tatcccagag gaattaaaat ggcgaaattg
     8041 ggctcatgct caaaatgggg aacgggtatt gacaggcgat gaattacttg attttgtcaa
     8101 taacaagtta ttcaaagagt tgaaagagct tgaaataact tcaattatgc ctattcgaaa
     8161 aacgattgtt aaatcagctt ttgaagatgc gaacaactat atgaaaaatg gcgtcttgtt
     8221 acgccaagtc atcaatgtta ttgatgaagt tgatttcaat agccctgaag atcgtcattc
     8281 gtttaatgat atttacgaaa aaattcttaa agatattcaa aatgctggga actcaggaga
     8341 attttatacg ccacgtgcag cgactgattt tattgccgaa gttcttaacc caaaacttgg
     8401 agaatcaatg gcagaccttg cttgcggaac aggaggcttc ttgacttcga ctctgaaccg
     8461 tttaagtagt caacgtaaaa ctagtgaaga taccaaaaaa tataatacag ctgtttttgg
     8521 tattgaaaag aaagcatttc ctcatctttt agcagttaca aatctgtttc ttcacgaaat
     8581 tgatgaccct aaaattgttc atggaaatac tttggagaaa aatgttcgtg aatatacgga
     8641 tgatgaaaaa tttgacatta ttatgatgaa tccacctttt ggagggtcag aattagaaac
     8701 aataaaaaat aactttccag cagaattacg gagttctgaa acagctgatt tatttatggc
     8761 tgtcattatg tatcgtttga aagaaaatgg tcgtgttgga gttattttac ctgatggttt
     8821 tctatttggt gaaggtgtaa aaactcgctt gaaacaaaaa ctggtagatg agttcaactt
     8881 gcatacgatt attaggttgc ctcatagtgt ctttgcaccg tatacaggaa tccatacgaa
     8941 cattcttttc tttgataaaa caaagaaaac agaagaaact tggttttatc gtttagatat
     9001 gccagatggt tataaaaatt tctcgaaaac taagccgatg aagtcagaac acttcaatcc
     9061 tgttcgtgac tggtgggaaa atcgtgaaga gattctggaa ggtaagttct acaaatctaa
     9121 atcatttaca cctagtgaat tggctgagtt gaattataat ttagaccagt gtggttttcc
     9181 aaaagaggaa gaggaaatct taaatccctt tgagttgatt cagaattatc aagcggaaag
     9241 agcaacttta aatcataaga ttgataatgt attagctgat attttgcagt tgttggagga
     9301 caaataatga caccagaaca acttaaggca agtattctcc aaagagcgat ggaagggaaa
     9361 ttagtgccgc aaaatcccaa tgacgaacct gcaagtgaat tattaaagag aattaaagct
     9421 gaaaaagaaa aacttatcag tgaaggaaaa atcaaacgag ataaaaagga aactgagata
     9481 tttcgtggtg atgatgggaa acattatggg aagtttgctg atggaag
//
LOCUS       DAVLUM010000073         9299 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLUM010000073 DAVLUM010000000
VERSION     DAVLUM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.073"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            463..1506
                     /locus_tag="VYN42_001733"
     CDS             463..1506
                     /locus_tag="VYN42_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1462779.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1673..3760
                     /gene="topA"
                     /locus_tag="VYN42_001734"
     CDS             1673..3760
                     /gene="topA"
                     /locus_tag="VYN42_001734"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1462780.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GGIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3866..4225
                     /locus_tag="VYN42_001735"
     CDS             3866..4225
                     /locus_tag="VYN42_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1462781.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4318..4950
                     /locus_tag="VYN42_001736"
     CDS             4318..4950
                     /locus_tag="VYN42_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1462782.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4994..5650
                     /locus_tag="VYN42_001737"
     CDS             4994..5650
                     /locus_tag="VYN42_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1462783.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5669..6763
                     /locus_tag="VYN42_001738"
     CDS             5669..6763
                     /locus_tag="VYN42_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1462784.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6775..7812
                     /gene="leuB"
                     /locus_tag="VYN42_001739"
                     /pseudo
     CDS             6775..7812
                     /gene="leuB"
                     /locus_tag="VYN42_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7809..8078
                     /locus_tag="VYN42_001740"
     CDS             7809..8078
                     /locus_tag="VYN42_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1462785.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            8082..8441
                     /gene="leuD"
                     /locus_tag="VYN42_001741"
     CDS             8082..8441
                     /gene="leuD"
                     /locus_tag="VYN42_001741"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1462786.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8603..9225
                     /locus_tag="VYN42_001742"
                     /pseudo
     CDS             8603..9225
                     /locus_tag="VYN42_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         2868 a         1633 c         2069 g         2729 t
ORIGIN      
        1 acactataat ttagtgtaat tgagaaagga gaaatgattg tgattgatgt tggctaggtt
       61 atgttcaatg attcctaccg tctcaaatct tgtcagtaag gaaaaataaa ttcttcaaaa
      121 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
      181 tggttattat aagaaatggt ctaaaataga tgatgatact tttcgaaaat ctttttacgt
      241 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
      301 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catttgagtc aggatattat
      361 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
      421 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
      481 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
      541 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
      601 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
      661 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
      721 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
      781 gctagttcgg agattgttgc tagaacctct ccgactattt gggatgttct cattgctttt
      841 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
      901 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
      961 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
     1021 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
     1081 gataatgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     1141 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     1201 aagaaattta tatcagagca gtttcagggg tataatattt tgaaaaaaac ctattctaaa
     1261 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     1321 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     1381 ttgtctgatt cagaacaact tagtaaggaa gaactggtgg agtatttctt ccagtatatc
     1441 aaggataagg aagcaaaaga aaaggaaaaa gccaataaat ttgatacaga gtctgaggag
     1501 caataatttc ttgagaatag ctggtttctc tcgtgagtct tctatgtata tcaaaggaag
     1561 actgaggttt taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc
     1621 aaaaaatggt ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac
     1681 ggcaacaaaa aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc
     1741 taaggccaag acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg
     1801 gcatatccgt gatttgaaga aatccagtat gtccgtcgat attgaaaata attatgaacc
     1861 gcaatatatc aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa
     1921 aaaagctaat aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg
     1981 gcatttggcc catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga
     2041 aatcaccaag gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt
     2101 ggtcgatgcc caacaagctc gtcggatctt ggatcgcttg gtagggtatt cgatttcgcc
     2161 tattttgtgg aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct
     2221 taaactcatc attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac
     2281 agttgatgct gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga
     2341 tggtaaaaag atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac
     2401 tagtaaagac ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt
     2461 accctatacc acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg
     2521 aaaaaccatg atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca
     2581 aggtttgatt acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga
     2641 ggcggcaagc ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt
     2701 caaaaacgca tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa
     2761 tacaccagaa agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat
     2821 ctggaatcgt tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa
     2881 attgtctcaa aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta
     2941 tcttgccatt tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga
     3001 tgtggtcaaa caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta
     3061 ttctgaagca acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta
     3121 cgcgccaacc attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt
     3181 tgaaccgaca gagttgggag gaattgtcaa taagctcatc gttgaatatt tcccagatat
     3241 cgtaaacgtg accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa
     3301 agagcagtgg cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa
     3361 ggctgaagaa gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga
     3421 agtgtgtggt agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag
     3481 caatttccca gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc
     3541 aagctgtcat cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tattctatgg
     3601 ttgcaatcgc tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg
     3661 tccaaaatgt ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt
     3721 ttgtagcaaa ggcgactacg aggaagaaaa gattaaataa gaggaggggc ccgaaagtaa
     3781 atttcaggct ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag
     3841 aagattattt taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
     3901 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt
     3961 gttgtctatt gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac
     4021 caagctctat caaacatatg tagctgattt tcgcgagacc aagtctatta cgcgtgaacg
     4081 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
     4141 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttatcactt attatctctt
     4201 caaggtcatt ccagacaaag aatagttaaa acagtagtta tttgccttga taaaattgaa
     4261 agcatattca taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg
     4321 atttacgaat tttgtgctga aaatgtgact ttacttgaaa aggcgatgca ggctggagct
     4381 cgtcggattg aactctgtga taatctagca gttggtggga caacacccag ctatggagtg
     4441 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
     4501 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
     4561 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gagctttaac tgctgataaa
     4621 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
     4681 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
     4741 agtcaagccg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
     4801 aaacgttttg ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta
     4861 ccaggtgggg ggattgacct tgacaaccgt caaaccttta ttgaccaggt gggggtaaca
     4921 caattgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
     4981 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
     5041 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
     5101 tgactttgtc atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca
     5161 agagactggt gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg
     5221 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
     5281 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
     5341 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
     5401 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
     5461 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tgctttcaca
     5521 aaaggggatt tatccagcct tccatatgag caagcgctac tggattagtg tgtcccttga
     5581 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
     5641 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
     5701 gaagagattt ttagaaaata taggatttac cacactagag gaatatggtg ccatcttcaa
     5761 atatctgatt gagaatgtca agacggatcg tcagatcatc tattcgcctc actgtcatga
     5821 tgacctcgga atggcagtgg caaatagcct tgctgctgtc aagaatggtg caggacgtgt
     5881 tgaagggact atcaatggta ttagggagcg agctgaaaat gctgctttgg aagaaattgc
     5941 agtggctctc aatattcgcc aagattacta ccaagtagaa accagtattg tcctaaatga
     6001 gaccatcaat acgtcagaaa tggtttctcg cttctctggt attccagttc ctaaaaacaa
     6061 agccgtcgtt ggtggcaata ccttctccca cgaatctggt attcaccaag atggagtcct
     6121 taaaaatcct ctcacttatg agatcatcac acctgaattg gttggtgtta agattctgct
     6181 tggaaaatta tctggtcgcc atgcttttgt tgagaaactg agagaattgg ccctagattt
     6241 tacagaagag gatatcaaac cactctttgc taagttcaag gcactggtcg ataagaagca
     6301 agaaatcaca gatgcagata ttcgagcttt ggtagctgga accatggttg aaaatccaga
     6361 aggcttccac tttgatgatt tacaacttca aactcatgca gataatgaca ttgaagcgct
     6421 cgttagccta gccaatatgg atggtgagaa agtcgaattt aatgcgacag ggcaaggttc
     6481 cgttgaagca atctttaatg ctatcgataa gttctttaac caatctgttc gtttggtgtc
     6541 ctacactatc gatgcggtaa cagatggaat cgatacccag gatcgggttt tggtcactgt
     6601 tgaaaacaga gatacagaaa ccatctttaa tgcagcaggg cttgattttg atgtgttgaa
     6661 ggcttctgct attgtctata taaacgctaa tacctttgtt caaaaagaga atgcaggtga
     6721 gatgggacgc agtgtttctt accacgatat gcctagtgtg taaaggagaa ggctatggca
     6781 aagaaaatag tagctctagc aggagacgga attggcccag aaatcatgga ggttggttta
     6841 gaagttctgg aggctctagc tgaaaaaaca ggttttgact atgagattga cagacgaccg
     6901 ttcggaggtg cagatattga tgcagcatga cctcccttac ctgatgaaac ccttaaggca
     6961 agtagggaag cagatgctat cctactagta gctatcggta gtcctcagta tgatggagca
     7021 gtggttcgcc ctgaacaagg cctgatggct ctccgtaagg aactcaatct ttacgctaat
     7081 attcgtcctg taaaaatctt tgacagtctc aagcatttgt cactactcaa actggaacga
     7141 attgctggtg tagactttgt cgtggtgcgt gaattgacag gcgggattta ctttggagat
     7201 catattcttg aagagcgcaa tgcgcgtgat atcaacgact atagctatga ggaagtggag
     7261 cggattattc gcaaagcctt tgaaattgca agaaatcgca gaaaaatcgt tactagtatc
     7321 gataagcaaa atgttctagc gacctcaaaa ctctggcgga aagtagctga ggaagtcgca
     7381 caggatttcc cagatgtaac cttggaacat cagctggtag actcagctgc tatgcttatg
     7441 attaccaatc ctgctaagtt tgatgttatt gtaacggaga atctttttgg agatatttta
     7501 tctgatgaat caagcgtctt atctggtaca cttggggtta tgccatcagc cagtcattct
     7561 gaaaatggac caagtctcta tgaacctatt cacggttcag cacctgatat tgcaggtcaa
     7621 ggaattgcca atcctatttc catgatttta tcagtttcca tgatgttgag agatagtttc
     7681 ggacgttatg aggatgcaga gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga
     7741 attttaacga gagatatagg aggtcaggct tcaacaaagg aaatgacgga agctattatt
     7801 gcaaggttat gaagttagac gaaaaaatta ctctagtcct tttgatttgg aatgtcatca
     7861 ttttcttgat ttatggtatt gacaaatcta aggcaaggag aagagtttgg cgcatccctg
     7921 agaaaatctt acttatttta gcctttactt ttggtggttt tggtgcctgg ctagcaggaa
     7981 tcatctttca ccacaagact cgaaaatggt actttaaaat agtttggttt cttgggatgg
     8041 tgaccacact agtagcctta tattttattt ggaggtaatg gatggcaggg tcttcgaggg
     8101 aatacgctgc ttgggctcta gcggactatg gttttaaggt cgtgattgca ggatctttcg
     8161 gtgacattca ttacaataat gaactcaata atggcatgtt gccaatcgtt cagcctagag
     8221 aggttagaga gaaactagcc cagctaaaac caaccgacca ggtaactgtg gacttggaac
     8281 aacaaaaaat catctcacca gttgaagaat tcaccttcga gatagatagc gagtggaaac
     8341 ataaactcct aaatagtttg gatgatatcg gtattacctt gcagtatgaa gagttgattg
     8401 ctgcttatga aaaacaacga ccagcctact ggcaggatta gaaaaaatag aaaaggagat
     8461 atagtaaact gaaataagat gtaaacaaat gaattggagc ttaacatcca tttccagcaa
     8521 ttttttagaa actacagtgg actattctgg attcaacaca ttataaaatt atgacaaaac
     8581 acattcacaa gaaggctacg acattttaaa aggtgagggc ggatgtatcg tttgccctac
     8641 taaagttggt tacattatca tgaccagcaa caaggcagga cttgagcgta agttcgcagc
     8701 caaagaacgt aagcgtaaca aaccaggtgt tgttctctgc ggtagcatgg atgaactttg
     8761 cgctttagcg caactcaacc cagaaattga agcattctac taaaaacatt gggatgaaga
     8821 tattcttctt ggttgtatcc ttccttggaa accagaagcc tttgaaaaac tcaaagcata
     8881 cggggatggc cgtgaagaac ttatgactga tgtacgtggt actagctgtt ttgttatcaa
     8941 gtttggaaaa gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta
     9001 cgcctcatct gcttcaatga caaaacgact gaaactcgct atgagcaagg tgtaatggtg
     9061 tctatggtcg ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacttca
     9121 ccagcaccag ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca
     9181 gatactttta actcatggaa ctaccgtcag gttgagtatt attaagataa aaaaagaagt
     9241 ctagtgttat gagatattaa agctcctaac actggacttt ttgtttagaa tttcttttc
//
LOCUS       DAVLUM010000074         9210 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLUM010000074 DAVLUM010000000
VERSION     DAVLUM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.074"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(44..1723)
                     /locus_tag="VYN42_001743"
     CDS             complement(44..1723)
                     /locus_tag="VYN42_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1462787.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1725..1958)
                     /locus_tag="VYN42_001744"
     CDS             complement(1725..1958)
                     /locus_tag="VYN42_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1462788.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(2776..2928)
                     /gene="cibB"
                     /locus_tag="VYN42_001745"
     CDS             complement(2776..2928)
                     /gene="cibB"
                     /locus_tag="VYN42_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1462789.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2930..3115)
                     /gene="cibA"
                     /locus_tag="VYN42_001746"
     CDS             complement(2930..3115)
                     /gene="cibA"
                     /locus_tag="VYN42_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1462790.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3293..3976
                     /gene="tsaB"
                     /locus_tag="VYN42_001747"
     CDS             3293..3976
                     /gene="tsaB"
                     /locus_tag="VYN42_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1462791.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPR
                     QKEGLVVPIMDARRNNVYAGFYENAKPVLPEAHLSFAEVLEQVKDAEQVTFVGEVGAF
                     VEQIQEQLPQASYQETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3973..4410
                     /gene="rimI"
                     /locus_tag="VYN42_001748"
     CDS             3973..4410
                     /gene="rimI"
                     /locus_tag="VYN42_001748"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1462792.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            4400..5410
                     /gene="tsaD"
                     /locus_tag="VYN42_001749"
     CDS             4400..5410
                     /gene="tsaD"
                     /locus_tag="VYN42_001749"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1462793.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5450..6756)
                     /locus_tag="VYN42_001750"
                     /pseudo
     CDS             complement(5450..6756)
                     /locus_tag="VYN42_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7095..7383)
                     /locus_tag="VYN42_001751"
                     /pseudo
     CDS             complement(7095..7383)
                     /locus_tag="VYN42_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7514..7783)
                     /locus_tag="VYN42_001752"
                     /pseudo
     CDS             complement(7514..7783)
                     /locus_tag="VYN42_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            8026..9168
                     /locus_tag="VYN42_001753"
     CDS             8026..9168
                     /locus_tag="VYN42_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1462794.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCISNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCTCANFLLNDSEYLKYIGENSKSKIRKHESI"
BASE COUNT         2685 a         1695 c         2069 g         2761 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttgaaga gtattattct tcatctggtg
       61 tgaggatcat cgggatgatg atcggttcac gttcggtatt ttcatagagg aaggggcgaa
      121 tagcgttgac aatggcacca ttgacagatt gcacgctagc atccttattt ttcagtgcga
      181 tacgaatggc attgaagagg atacgctggc tttggcgaat caagtcgcca gactctctca
      241 tgtagacaaa gcctcggctg aggatgtctg gaccagatag aatcatctgc gatttgaagt
      301 caacagttgc gactgccaga acgacaccgt cttcagatag atcgcgacga tctttgagga
      361 cagctgcgcc aatttcaccg atacgatttc catcgacata gatatcttgg gcgttgaaat
      421 gacctgcgat acgagctgag tcagcagtaa gggcaagcac atcgccattg ctcatgataa
      481 agatattgtc cttctcaaca ccagtatcca ctgctagtcc agcgtggact ttttgcatgc
      541 ggtattcacc gtggacaggc atgaagtatt ttggcttaat caagcagagc atgagttttt
      601 gctcttgctg accaccgtgt ccagatgtat ggatattgtt cactttaccg tggataactt
      661 cgacaccagc ttcagaaatg atgttaatca gcttgttgac gctagtagtg tttccaggga
      721 tgggactaga agagaagata acggtatcac ctggttgtaa ttgtacttga cggtgggttc
      781 cgttggcgat acgagagagg gctgccatag gctcaccctg actacctgta cagaggataa
      841 gaacttctcc tgcaggataa tctttgattt catttggctc gataaaggtt cccttaggag
      901 ctttgatgta gccaagatcg attccgttga caatggcctt ttccatagaa cgaccaaaga
      961 ccgcaatctt gcgtccagtc ttaacagcag cttctgttgc ctgctggaga cggaagatat
     1021 ttgaggcaaa ggatgcaaag atgatacgtc cttcaatacc ttggataatc ttcataatgg
     1081 actgaccaac gactttttca gagttggtaa aggttggtac ttccgcattt gtcgagtcag
     1141 acaggagaca gagcacacct tcttcaccaa gcgcagccat acgatgcaag tccgcaggtt
     1201 ctccaactgg agtaaagtcg aacttaaagt cccccgtaca gacgattttc ccttgaggag
     1261 tatgaatgac aatccccaaa ggctctggaa tagagtgagt cgttctaaag aaagttgcct
     1321 tgagattttt aaaggtcaac tcggtgttgt ggttgatttc gtaaagtttg gcgttgcgca
     1381 agaggccgtg ttcttcgagt ttcccacgga tcaaagccaa ggcaagcggt ccagcgtaga
     1441 tagggacatt tgcttgcttg agtaggaacg gaatcccacc aatgtggtcc tcgtgtccgt
     1501 gtgtgattaa aacagccttg acgcggtcga tattgtccac gatgtaagag tagtcaggaa
     1561 tgacatagtc gataccaagc aagtcatctt ctgggaattt aatcccagca tcgacgatga
     1621 taatctcgtc ttggtattca attccgtaag tgtttttccc gatttctcct agaccaccga
     1681 tggcaaaaac gccgacttct tcaggtttaa gagtgtaggc catattagaa ctccgtaatt
     1741 tcgaaggcgc cagtttcttt ttcgtaatcg agcaatttgt cagacaagag ttcgatatat
     1801 tcgatattgt actctgggcg attttcttcg acaagttggc gagcagtgat acggccctca
     1861 agttctgagc tggcatcgat gtctaggtaa agcgcgcgtg ttgtttcacg gcgtgggcta
     1921 cgttcttttg tttcttgata aaaaactttg taaatcatat agttcctttc tatttacagg
     1981 tcagcttatt ccaaactttt agcagatatt tgcttgattt cattccattt tgtgtctaga
     2041 ttgaccttga ttcgttacaa ttatttcaat tataccacaa aatgaaaaat tagtaaaaga
     2101 cggaaacgag aaagttaggg ggcaatttct ttggtaagcg tttacaaaaa taaagaaaat
     2161 gtattatgtt gataacggaa gtgaaattta ttgcttgtca taattccata tagattttaa
     2221 gtcaaggagg ttgccctatg tataacttat ttgcttttgc tatcggagtt cgtttgttag
     2281 cttttatcgt ttttgttgct tgcgtttatg gaggaaatct tccatttgcc aaactggaac
     2341 gatgacaaac caagttcttg tggaaaatga cctttgtgac tctctactcg ctttttctcc
     2401 tcctcgtgcc ctatgtcgtt tggtttgtat tttactttgg attaaatgct tagatgccct
     2461 gcttatgctg gggttttttg tttggggatg tagagatagt agatttacga cacgaaaatt
     2521 ccaccccatc tatcaagatg aggtggtctt tgcatttttc taaaatgaca tgacaatgga
     2581 attttcaaag cttattattt ttatgggagt cattgttctg ctcaaaaata gagttgaagc
     2641 ataaaaataa aacaatacaa acagataaat cgaatggtaa agggatagta gtaatgttca
     2701 aatcattgag aatgctgagc aaactgtaag agatgaagac aataaaattt atccttctaa
     2761 aaatgtgttt cttatctagc atgacttacc aaacttttta cgaaggtctt ttccaatggt
     2821 ataacctgcc ataaataaag cgataccaac acctacacca aagccaccct tgatttcttg
     2881 caattcctta ttagaaattt cacgatagtt gttcaaattt ttcatcatat taatctcctc
     2941 ctaaaaaata accagctgcc aaaccagaac ctataagtgc tgttccacct gcaatagcct
     3001 tccaagatac tgctactcca aagataacca agggagcgag accgccatca atatctgata
     3061 attcattttc agataaggat aaaaattgat tgtcaagaat gtcaaaattt gtcattgaac
     3121 tttcctcctt ttttcttgtt cacttttata ttcggaaaag aaaaggaaaa gtgagcattt
     3181 ttttaaatta tttttagtta agtgagggca ctcttgtctg ggggcaaaga aaattcccat
     3241 gtgccagctt ttgtagtata atagtaagca gacaaaaaga taggaatgtg ttatgaaagt
     3301 attagctttt gatacgtcca gcaaggctct ttctctcgct attttagagg acaagcaggt
     3361 tcttgccgag acgacgatta atattaagaa aaatcacagt attactctta tgcctgccat
     3421 agattttttg atggcaagtt tggattggac acccaaggat ttggaccgaa tcgtggtagc
     3481 tgaagggccg ggtagctata caggcttgcg aattgcggta gcaactgcca agaccttggc
     3541 tcataccctg aacattgagt tagttgggat gtctagtcta ttggctctgg tgccacgcca
     3601 aaaagaaggc ttggtggttc ctatcatgga tgcgcgtcgc aacaatgtct atgcaggctt
     3661 ttatgaaaat gccaagccag tcttgccaga agcgcatctg tcttttgcgg aagtgctaga
     3721 gcaggtcaag gatgctgagc aggtgacctt tgtcggagaa gttggagcct ttgtggaaca
     3781 gatccaagaa caactaccac aagccagcta ccaagaaacc ttgccaaatg cagctaatct
     3841 agctctttgg gcttgggaca aagaagcaga ctccttgcac gactttgtgc caaattacct
     3901 caagcgtgtc gaggctgagg aaaactggct caagaaccat accgagtctg gcgagtctta
     3961 cattaaacgc ctatgataga aatcaaacga atccaacagc agcctgatct agctaaagcc
     4021 atctacgctg ttatgatagc tgtttaccca gtcagtcctt ggacgctgga acaaatccaa
     4081 gctgacctgt tccaagacca gacttggtat gctctggctt atgatggggc agaagtgatt
     4141 ggctttctag ctgttcagga gactctcttt gaagcagaag tcctgcaaat cgctgtcaaa
     4201 ggagcctatc agggtaaggg cattgcgtca gccttgtttg ctcaattgcc gacagataag
     4261 gagattttcc tcgaagtcag aaagtcaaat caacgagcgc aagcatttta caagaaagaa
     4321 aaaatggcgg tcatcgctga tcgaaaggcc tactaccatg acccagtcga ggacgccatt
     4381 atcatgaaga gagaaataga tgaaggatag atatatttta gcatttgaga catcctgtga
     4441 tgagaccagt gtcgccgtct tgaaaaacga cgatgagctc ttgtccaatg tcattgctag
     4501 tcaaattgag agtcacaaac gttttggtgg cgtagtgccc gaagtagcca gtcgtcacca
     4561 tgtcgaggtc attacagcct gtatcgagga ggcattggca gaagcaggga ttaccgaaga
     4621 ggacgtgaca gctgttgcgg ttacctacgg accaggcttg gtcggagcct tgctagttgg
     4681 tttgtcagct gccaaggcct ttgcttgggc tcacggactt ccactgattc ctgttaatca
     4741 catggctggg cacctcatgg cagctcagag tgtggagcct ttggagtttc ccttgctagc
     4801 ccttttagtc agtggtgggc acacagagtt ggtctatgtt tctgaggctg gcgattacaa
     4861 gattgttggg gagacacgag acgatgcagt tggggaggct tatgacaagg tcggtcgtgt
     4921 catgggcttg acctatcctg caggtcgtga gattgacgag ctggctcatc aggggcagga
     4981 tatttatgat ttcccccgtg ccatgattaa ggaagataat ctggagttct ccttctcagg
     5041 tttgaaatct gcctttatca atcttcatca caatgccgag caaaagggag aaagcctgtc
     5101 tacagaagat ttgtgtgctt ccttccaagc agcagttatg gacattctca tggcaaaaac
     5161 caagaaggct ttggagaaat atcctgttaa aaccctagtt gtggcaggtg gtgtggcagc
     5221 caataaaggt ctcagagaac gcctagcagc cgaaatcaca gatgtcaagg ttatcatccc
     5281 ccctctgcga ctctgcggag acaatgcagg tatgattgcc tatgccagcg tcagcgagtg
     5341 gaacaaagaa aacttcgcag gctgggacct caatgccaaa ccaagtcttg cctttgatac
     5401 catggaataa agagtggctc tttgtcaagt gtagtgggta ggcgaaaagc tacaatctgg
     5461 agagtacgaa attcgtactc tcttttttga tgttcaaagt catcaaaatc cgttttttaa
     5521 aattgttaaa gttccggaaa ccaaaggctt tgcgcttgat aaccttaata aaattattgg
     5581 tcgcttcaag tttagcgttg gaataaggca gcttaagtgc gttgataatc ttatctctat
     5641 cccttaaaaa agtccaaaag accgtttgaa aaagcggatg aaccgttggc agttcttgct
     5701 caatcaatcc aaagaaatgg tcggcattct tctcttgaaa atgaaagagc aggagttgat
     5761 agagttcgta gtgaacctgt aatccctcag agtaagaaag cagcttatct cgtacttccc
     5821 gatgggttaa gtgcattcga aacgtgggct gatagaatcg tttctgacag agcttgaagc
     5881 tatcctggtg tagtaaatca gtccagtgga ctgatttagc ccgagcctag aaacgaaaaa
     5941 gcgagggttc caaaagcgct tgagcgcccg atactccaag gattttcggt caaattggtt
     6001 catgatttgg attcgtactc ggttcatagc tcggctcaga tgttggacaa tgtggaagcg
     6061 gtcaagaaca atcttcgcct ttggaaagag ttgcttagcg agccgataat aagggctgta
     6121 catgtccatg gtgatgacct cgaccagctc ccgaacctct ctctgatagc gttggaaatg
     6181 gtttcgaatc accgcatgag ttcgcccgtc taaaattgcg aggatggatt tggactcaaa
     6241 atcttgggca atgaagctca ttttgctctt tttgaagcta tactcatccc aactcataac
     6301 ttttggcaac ttggtccaat cggtttcaaa cttaaattcc ctcagttttc ggatgacggt
     6361 ggaagttgag accgccaatc tgtgggcaat ctcagtcata gactgctttt caaggaggag
     6421 ctgagcgatt ttttgtctca ccatgttgga aatctggcaa tttttcttga caatggatgt
     6481 ttgagaaacg accaccttaa ggcaattctt gcactgaaag cggcgctttt tgagatgcag
     6541 taccgtgggt aaaccctgac agtcgagaag cggaatttta gaggctttct ggaagtcgta
     6601 tttgatcatc ttcccttgac aatgaggaca aggaggagtg ggggaatcca actttgcctg
     6661 aacgactaga tgggtttggt atttcagaac agacaagatt ttgatatttt tgtcttccaa
     6721 tccgagcaaa tctgtggtat tcttaagttg ttccatatga cccctttcta atgagttggt
     6781 tagacgcttt tcattatagg tcatatgggg ctttttttct acaagaaacg accctataat
     6841 tcctggggtg ggattaccca ctacagaaat tatagagcca aaacattcca aagtcttgtc
     6901 tgactctgga atgttttctg ttcacagttg ttttgtaact gcctaataag taaccgcgct
     6961 ataacgaggt atctaccgag attgtcaatt ctccagtata ctgttataaa aaacaaaact
     7021 ggaggatttt tttatgtccc cccatcgtcc catcgactgt tccgtagctg cccaataacg
     7081 gagtatagtc gtctgaaaca agaataggac aaaagtgcct caagaaaagc atcgtaattt
     7141 gacaatatta ttctgagatg tttttgatgt aagcccatat tttctcaatg ggattatact
     7201 cgggtgaata ggtaggaagt ggtaacagtc tatgccctgc tccttacaca tgttcattct
     7261 gtgaaacctt gcattgtcca taatgataag ggatggtgta tctaaagtag gtagtaagaa
     7321 tttttggaag caagcttcga aaaagtcact cgtcatcgta tctttatagg tcatcggagc
     7381 catagtatat tgaaacaaaa aagggtatta gtacttctat aacagtatcg caatctctgg
     7441 tgtgcgttgt ctcgatctta attcaaataa ttatatcttc ttccagagag actaactgcc
     7501 tgctcaagga tcaatcatat tcgagataaa aataggtctc aacccctgtc tcataaatat
     7561 aaataggagt caggtagctt aagtgattca attctttaag gaaccgattt actttttctt
     7621 ggtcttgttc gcagtaggta cggctctttt ttagactata tcccatagcc tttagagcgt
     7681 aatgaatagt tgttggagga cagttgaatt cagcagctat ttcagtcaaa taagcatcgg
     7741 gatgagtttc aatatagatc tttaatttat ctctatcaac tttttcaatt aatagtggaa
     7801 gttttcttga agttagtgta ttgaaacgtt tttatacagt gctaaaattt gaagtgtagt
     7861 gcagatgtat ttgtaatagt attatagcaa ttctttggag aaggtcgaga caagagaaaa
     7921 taggtatctt tgagatataa gcatgattta ctataaaatt attgagttat tcataaaaat
     7981 ttctctatca aatatcataa tgcgtcgttt aaggagatgg ttacaatgca atatagttgt
     8041 ggaaaaataa atattaatat ccctgatgga tatggagaca ttaaggatat agtgttttcg
     8101 gctcatatta tagttaggta taataatgga cattgtggag gtatagatcc gcatataatt
     8161 ggactttgta aaaagcagat cagaaggatg tctctatatc ctattttgat aatcgtatct
     8221 agagattcaa aggttattga tgattataaa aatttagata ttgcctatgt tgattgtact
     8281 caatgttcaa ataattttga aactgcctta cacgttaaaa atattttaaa attattaaaa
     8341 atccaactta tacactgtca tggctactca actaattatt ttttatatat gttaaaaaaa
     8401 cttgacaaga atggatttgg aaaggttaag acagtgataa catgccatgg atgggttgaa
     8461 tataacttaa aaaagaaatt cttgacttat tttgattttt ggacatattc tatgggagat
     8521 gcttttattt gtgtatctga aactatgaaa aaaagattgg agagtataat aaaaaataag
     8581 aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga tgtagtaggt
     8641 gttcaagact ttaaaaaaga attttgtatt tcaaataaca aaaaaatcat ttgttatgtt
     8701 ggaaggttgg atccagaaaa aaggccggat agattccttg aatttgcaga aaaattattt
     8761 ttagtcagag aagatgtgat ttttattatg gctggaaatg gtagtatgtg ggctgctttg
     8821 aaagaaaaaa tttgccattt gaaatgtaga gataatttca ggttacttgg tgaaatctat
     8881 ccagctacta tagtttacca aatatcggat ttattgtata ttccttctga tacagaagga
     8941 atacctatgt gtgttttaga gtcaatgtca caaggaactc cggttttagc tagtaatgtt
     9001 ggcgggttaa gtgaaattat tgaacatagg gttgatggat ttttatttga gaaggaagat
     9061 gttgagggag tgtgtacttg tgctaatttt ttactcaatg attctgagta tttgaaatat
     9121 ataggtgaga atagtaaatc aaaaataaga aaacatgaga gtatatgatg aattattaga
     9181 gaagagtagt catggatagg aatatagatc
//
LOCUS       DAVLUM010000075         9120 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLUM010000075 DAVLUM010000000
VERSION     DAVLUM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.075"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..820
                     /locus_tag="VYN42_001754"
     CDS             <1..820
                     /locus_tag="VYN42_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1462795.1"
                     /translation="LALLLKAIKLARWTYYYHLKQLDKPDKDQELKAEIQSIFIEHKG
                     NYGYRRIYLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSHKGDVGKKAENLIQ
                     GQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSISPNLEQVQTM
                     LEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMEFFFG
                     ILKSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKVKLKGLSLVQYRTKSFG"
     gene            complement(949..1152)
                     /locus_tag="VYN42_001755"
     CDS             complement(949..1152)
                     /locus_tag="VYN42_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462796.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1145..2227)
                     /locus_tag="VYN42_001756"
     CDS             complement(1145..2227)
                     /locus_tag="VYN42_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1462797.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2353..3135)
                     /locus_tag="VYN42_001757"
     CDS             complement(2353..3135)
                     /locus_tag="VYN42_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1462798.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3135..4478)
                     /locus_tag="VYN42_001758"
     CDS             complement(3135..4478)
                     /locus_tag="VYN42_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1462799.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRYGEIYTTYKMILDAIRKVPT
                     ATVLLNGDSPLFYKPAIPNPVEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4577..5893)
                     /locus_tag="VYN42_001759"
     CDS             complement(4577..5893)
                     /locus_tag="VYN42_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1462800.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6087..7313
                     /locus_tag="VYN42_001760"
     CDS             6087..7313
                     /locus_tag="VYN42_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1462801.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7512..9086
                     /locus_tag="VYN42_001761"
     CDS             7512..9086
                     /locus_tag="VYN42_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1462802.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2656 a         1770 c         2000 g         2694 t
ORIGIN      
        1 gttagctctt cttctaaaag ccattaaact agctcgttgg acctactact atcacttgaa
       61 acagctagat aaaccagata aggaccaaga gcttaaagct gaaattcaat ccatctttat
      121 cgaacacaag ggaaattatg gttatcgtcg aatttattta gaactaagaa atcgtggtta
      181 tctggtaaat cataaaagag ttcaaggctt gatgaaagta ctcaatttac aagctaaaat
      241 gcgacagaaa cgaaaatatt cttctcataa aggagacgtt ggtaagaaag cagagaatct
      301 cattcaaggc caatttgaag gctctaaaac aatggaaaag tgctacacag atgtgacaga
      361 atttgccatt ccagcaagta ctcaaaagct ttacttatca ccagttttag atggctttaa
      421 cagtgaaatt atcgcctata atctttcaat ttcacccaac ttagaacaag tacaaacaat
      481 gttggaacaa gccttcacag agaagcacta cgagaatacg attctccata gtgaccaagg
      541 ctggcaatat caacacgatt cttatcatca gtttcttgag ggtaagggaa ttcaagcatc
      601 catgtcacgc aagggaaaca gccaagacaa cggtatgatg gagttcttct ttgggattct
      661 gaaatcggaa atgttttatg gctatgagaa aacatttaaa tcacttaatc aattggaaca
      721 agctattgta gactatattg attactacaa caataaacga attaaggtaa aactaaaagg
      781 acttagcctt gtgcaataca gaactaaatc cttcggataa attaattgtc taacttttgg
      841 ggggcagtac atattcaaca cctgatacta tgcgttttat tgtgggaaga ttttcctcat
      901 tttctagtga aattgaactt tttctaacat cttttgatag atgacttctt aatcaattat
      961 catttccatt gttgtttctt ggggtttcat cccttgtctt tgataaaagc ggagagcacc
     1021 ctcgttatca ttccagacac ttagggttag attattgcag ccaatttctt tagcataata
     1081 gcagaaaaat gacaataaaa tagcccctag atattttgaa aggaaagcat aggggctata
     1141 tagtttaatc aaaataaagc aaatctttgc tggtgcttgt aaagaggtcg aagccatcct
     1201 tggtaacaac accgcagtct tcaatacgaa caccgacttt accagggata tagatacctg
     1261 gttcaacaga gaagcacatg ccttcttcga tgaccatgtc gtttccttcc atgatagatg
     1321 ggaattcatg gacatccata ccgataccat gcccgagacg gtggttgaag tactcaccat
     1381 aaccagcttt ttcgatgacc tcacgggcag cgcggtccac ttcatgagca gtcacacctg
     1441 gcttgataaa gtcaagagca gcttgttggg cttcaagagt caagttgtaa atatctttct
     1501 tgaattggtc tggtttgccg acagcgactg tacgagtcat atctgacgca tagccattga
     1561 ccagaacacc caggtcaaag aggagaagag catcattttc aaccttatta gctgctggaa
     1621 tgccgtgtgg attcgcagca ttatcaccag tcaagaccat ggtatcaaag ctcatttcgt
     1681 aaccttcacg tttcatggca aagtcaattt gtgcgatgat atctgtctca gtcttatcaa
     1741 gagaaatatt gtcaaaacca acatgaacag ccttgtcagc ataaagacct gcaaccatca
     1801 ttttttgcac ttcatcagct gatttgatga ggcgcatgcg ttggatacga ggagtgaggt
     1861 tgtcaaactc agcagtctca aaaactgttt tcaaaccatg gtatttggtc aagatgagat
     1921 tgtcaaactc aacagcgaca cgtttgaagt caagttgtgg aagagcatgt ttgatttttt
     1981 gccatggatt ttcagaatcg acataaccca ctactgggaa ggaaacggtg ctacttgcac
     2041 gttctacttc aagagctggg acaaagagga gaggttcctg atccgctagg acaaagagga
     2101 acatttggcg ttcatgggga tcactgtaaa aaccagtgag gtaattgatt gtgacggggt
     2161 cagatacgac agcgacgtct agtttttctg attcaagata tgttaggatt tgttgtaatt
     2221 tagacatatg ctaccttctt tctacccctc tattttggca aaaaatgaga gaaaatgcaa
     2281 gggagaaggg taaaagaaaa gacaaaaaac tccgacaaga taacggagtt ctttgatatc
     2341 attttccttt gtttaagaaa agtcagcctt gcttttgacg tcactgtact cttcagcgat
     2401 ttcttggctg aggatatcct cataggcagg gagttggata tcctgaccat atttcttctt
     2461 gagggcagta gtaactaggc gataagccag attggcatta cgagagagga taggcccgtg
     2521 gaagtaggaa ccaaagacat tcttataatg aaccccttca ccgacctttt cttcgttgtt
     2581 tccatttcca tagacaacct gtcccagcgg tttttggtca tcagagagga aggtacggcc
     2641 ttggtgattt tcaaatccat agtaggtttc atcgaaatct tcattgtgaa tcttgatgtc
     2701 accgataaaa cggttattgg tctggttgag cgtgtagtgt cccatgaccc ctagcccttc
     2761 gatacgtttt cctgaagctt caacataata ttgacccaat agttggaaac caccgcagat
     2821 agccagaact acaccgtcgt tttggatgta gttgtcaatg ctctcttttt tagcaggtag
     2881 gtcgtctgca atgatacttt gttcaaagtc ttgaccacca ccgaaaaagg cgatgtcgta
     2941 gtgattttca tcaaagtcat catggagaga aacgatgtca acggtcacat gggctcccag
     3001 tttttcagcc acatacttga gcatgaggat gtttccattg tccccgtagg tattcatgag
     3061 atttccgtag aggtgggcaa tgttgagctg ataggggtaa ttgccatctt ttgaggaaag
     3121 tgaagtataa accattagtt catctccttt ctaacaatct gacgactagc cagcagttca
     3181 cgaaattcca gcatggcagt ataagttgcc agaatatagg catgcttgca gtcttgattc
     3241 tcaatggtct tgagaacttg ctccagatta ctcgtttcag tgattttctc agctggatag
     3301 ccagtcactc ggaggcgacg agcgatttca gaatgacgaa caccgccagc gttgatttca
     3361 ggaatgtcca tgtcagtgat ttgttcaaag tctgcatccc agatccagct agtgtcaatt
     3421 ccatctgcat agttggcatt aaggaggaca gataggctaa atggataagg tgctagtttg
     3481 atcatttcga tagcttgggt tgcaccgact ggatttttaa tcaagacaag ggtacattcc
     3541 ttgtcaccaa tatgaaaggt ttcttggcgt ccaaagacag cacggctctt gtcaaatccc
     3601 tgtttgatga gttgggaatc tgcgccgagg aaacgggcga tggccacagc agctagggcg
     3661 ttatagatat tatagagccc gccgatttgg ataccgtatt cttggccgtc tatgacaaag
     3721 cgagagcgat tgttggtcaa ctcaaccagt tttgtcaaac gatagtcgag atcaggacgt
     3781 ttacatccac aaccttcaca gatataggca cccaagtttg cataggtatt atgctcatat
     3841 ttgaggatgc cttggcagtc aggacagagg attccttcgg tattatagtg agccagctgg
     3901 gctggacctt tctccaagtc aaaaccaaaa tactctacag gatttggaat agctggcttg
     3961 tagaaaagtg gactgtctcc attaaggaga acagtggcag taggcacctt acgaatggca
     4021 tccaaaatca tcttgtaagt tgtgtaaatc tcaccatagc ggtccatctg gtcacggaaa
     4081 atattagtaa taacaaataa gcttggctgg atatagtcac agatacgaga tagactggcc
     4141 tcgtcgattt ctaggacggc aatatttttc ccagttttag aagatttggc tgttaagaag
     4201 gttgtcgcaa ttcctgtaat catgttggca ccgcttgggt tggtcagaac ttgaccataa
     4261 acttctttta aaataccgac agtgagggca gttgtcaggg tttttccatt tgttccagtg
     4321 acaacgacaa tctcgtagtt cttagctagg ttttgtaaaa tatctttatc aaattgaagg
     4381 gcgactttac ctgggagcgt acttccacgt ccaagacggc ttaaaacgaa gtgggaagaa
     4441 cgcccagcaa gaaggcccaa agtagttttt aagttcatgt ttctattata tcacaaaaga
     4501 gggaaaagac agatttggtg tttcgtagaa gtaaaaacag cccaaagagg gctgtcagtt
     4561 aagatgagat ttcaacttaa atcgcaaaca agtcattcaa gttctcagcc aaggttgggt
     4621 gagtgaaaat ttgttttgtg aagtaagtgt aaggaatctt gttgtccata gcaacagtaa
     4681 tgatgttgat gatttcttga gaaccttctg agaagatgct tgctccaaga atttcttttg
     4741 tttcagtatt aacaacagct ttgaaagctc cgcgaaggtc tccatttacg tgaccacgag
     4801 gcatggctgc aacagggatt tctttcactg cgtatggaag tttcaaatca gctgcttggc
     4861 tttcagtcaa accaacttgt gaaagtgcag gtgtgatgaa catagtattt ggcacattga
     4921 gacggtcctc aagtgtgtag ctgccatctc cagcaaggta gctgtaaaca acacggaagt
     4981 catcaagtga aatgtaagta aattgaagac caccgttgac atctccaact gcaaagacac
     5041 caggaacgtt tgtttgacag tgtttatcta ctttaatagc gccacgttca gttagttcaa
     5101 tatctgtatt ttcaagttga agtggttcta catttggttt gcgtccagtt gcgtagagaa
     5161 gggcgtcgaa acggtaagtt tcgtcttcag ttacgacaag cacttggtca ccgtcgtttt
     5221 taatttcagt agtatggata ttttgaagca attcaatacc gtcttcttcc aggtattgtt
     5281 tagcaagagc tgcgatggaa ggttctgcac gaggtaggaa tgtatccaag gcatctagga
     5341 ctgtaacctt gcttcctagt ttattgtaaa ggccagcaaa ttcaagaccg atatttccgc
     5401 caccaaggac tccaagtttt tcaggcaatt tatccaagct ttggatacct gttgagtcaa
     5461 agacgttttt gcttgtagca agtccaggga ttggcaagac gtttgaaaca gcaccagtgt
     5521 tgatgacgat agtttcagca gtcaattctt gtttttcatc accagcttgg atttcgatga
     5581 ctttatttga aaggaagtga gcttcagcat caaagatatt gacgccagta ccagcaacag
     5641 tcgtgtagtt tttaccgttg aggcgaccag tgatcgtgtt tttggtagca atgacttctt
     5701 caaaagataa gtctttctca gcagcaacca gcaaagtttt agttgggata caaccgatgt
     5761 tgatacaagt tccaccgtac atagctttgc tacgttcaac gagggcaact tttttgccag
     5821 ctgaagccaa tttacctgct agtgttttac cagctttacc aaatccgata acgattaaat
     5881 cataagttaa catttagagt tcctcctatt cgcatttcat tctagcacaa gaaaaaaact
     5941 tttgcacaat tctgctacgg aaaagacaga aaaagataaa aacgctttcc agacaaaaaa
     6001 ctagtaattt tttgacaagc ttgataaact aaaatcctat ctatttttat ataagataga
     6061 ataaatgttc gaaaatagga ggttttatga aatcgaatcg ttatattatt gcctttgctg
     6121 gggtcatttt acacttaatg ctgggttcga cttatgcttg gagtgtttat cgtaacccta
     6181 ttattgaaaa aacgggatgg gatcaggctt ctgttgcctt tgcctttagt ctagcaatct
     6241 tttgtttggg cttatcggct gcatttatgg ggcgtttggt agaaaaattt ggtccgagag
     6301 tcatggggag tctatctgct tttctatacg caggtggaaa tatcttaaca ggatttgcaa
     6361 tagaccgtca ggagctgtgg ttgttgtatc tcgcttatgg cattttaggt gggcttggtt
     6421 tgggagcagg ctatattacc cctgtgtcga cgattataaa atggtttcct gataaacgtg
     6481 gtctcgcaac aggtttagcg attatggggt ttggttttgc ttctttattg actagtccca
     6541 tagcgcaaca cctcatcgca ggggtaggga ttgtagaaac tttttatatt ttaggagcaa
     6601 gttactttat tatcatgctc ctagcttcac aattcattaa gcgtccaaat gagcaagagc
     6661 ttgcaatttt atcttcttca gggaaagaaa aaacagcctc tttgacgcaa ggaatggctg
     6721 caaatcaggc tctaaaaagc aatcggtttt atatgctttg gattattttc tttatcaaca
     6781 tagcttgtgg tttaggctta atttcagcgg catcgccaat ggcacaggag atggctggct
     6841 tgtctacaag tcatgcagca gtaatggtgg gtgttttggg gattttcaat ggatttggtc
     6901 gcttgctctg ggcgagtttg tctgactata tcggtcgccc tctaaccttt agtatattac
     6961 tgcttgtcaa tcttttcttt tctctctcac tttggctctt tacagattcc gttttatttg
     7021 tagttgctat gtctattttg atgacttgct atggagctgg tttttctttg attccagctt
     7081 atctcagtga tatttttgga accaaggaat tggccgctct gcatggttat attttaacag
     7141 cttgggcaat ggctggttta gcgggaccta ttttattagc agagacttat aaaatggctc
     7201 attcgtacac acaaaccttg ttcgtttttc tcattttata cagtatcgcc ttggctttgt
     7261 cttattatct aggtcgttca atcaaaaaag aaagtcaaaa accgcttaca tgattttctg
     7321 tagaaatggg gctatctttt gctctggtct tgtgttatac tagataggtt gcaaagaaaa
     7381 cagtactttt cttttgtgga aaagaagcaa cacgatttta tatctagtta tatgaaaata
     7441 cgtcataaaa agaaaagtat aaactaagcc ctatagggtg gcttcgcacc acctttagaa
     7501 agaagaataa cgtgaaattt aatgaattaa acttgtctgc tgatttgctg gcagaaattg
     7561 aaaaagctgg ttttgtagaa gctagtccta tccaagaaca aactattcct ttggcccttg
     7621 aaggcaagga tgttatcggt caagctcaga ctggtacagg aaaaactgca gcctttggct
     7681 tgcctaccct tgaaaaaatc cgtacagaag aagcgactat ccaagctttg gtcatcgctc
     7741 caactcgtga actagctgtc caaagtcaag aagaactctt ccgctttggt cgtagtaagg
     7801 gagtcaaagt ccgttcagta tatggcggat caagcattga aaaacaaatt aaggctctta
     7861 aatctggtgc ccatatcgtg gtgggaactc caggtcgcct cttggacttg attaaacgca
     7921 aggccttgaa attacaagac attgaaaccc ttatccttga cgaagcggat gaaatgctta
     7981 acatgggctt ccttgaagac atcgaagcca ttatttcccg tgtacctgaa aaccgtcaaa
     8041 ctttgctttt ctcagcaact atgccagatg ccatcaaacg tatcggtgtt cagtttatga
     8101 aagcccctga gcatgtcaag attgcggcta aggaattgac aacagaattg gttgaccagt
     8161 actatatccg tgttaaggaa caagaaaaat ttgacaccat gactcgtctc atggatgtgg
     8221 cacaaccaga actcgctatt gtatttggtc gtaccaaacg ccgtgtggat gaattgactc
     8281 gtggtttgaa aattcgtggc ttccgtgcag aaggaattca tggcgaccta gaccaaaaca
     8341 aacgtcttcg tgtccttcgt gactttaaaa atggcaatct tgatgttttg gttgcgacag
     8401 acgttgcagc gcgtggtttg gatatttcag gtgtgaccca tgtctacaac tacgatattc
     8461 cacaagatcc tgagagttat gttcaccgta tcggtcgtac aggtcgtgct ggtaagtcag
     8521 gtcaatctat tacttttgtt gctccaaacg aaatgggtta ccttcaaatc attgaaaact
     8581 tgactaagaa acgcatgaaa ggtctcaaac ctgcaagtgt agaagaatcc ttccaatcaa
     8641 aaaaacaggt agctctcaag aaaatcgaac gtgattttgc agatgaaacc attcgtgcca
     8701 actttgagaa atttggtaag gatgctcgca aattggctgc tgagtttact ccagaagaat
     8761 tggcaatgta tatcttgagt ctgacagtcc aagacccaga tagccttcca gaagtggaga
     8821 ttgcacgtga aaaaccacta ccgtttaaac catcaggtaa tggtttcggt ggtaaagcta
     8881 agggaggtcg tggaggccgt cgtggggacg accgtcgaga gcgtgatcgt cgtggcaatg
     8941 gtcgccgtga tgagttcaaa aaaggaagtc gtggcaacga tcgttttgat aaggaaaaac
     9001 gttaccgtaa ggataataaa aaaccacgca atactttaag cgaaaagcaa acaggctttg
     9061 ttattcgtaa caaaggtgat aaataagaaa aagcggttca aaatgaatcg cttttttata
//
LOCUS       DAVLUM010000076         9059 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLUM010000076 DAVLUM010000000
VERSION     DAVLUM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.076"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            178..495
                     /locus_tag="VYN42_001762"
     CDS             178..495
                     /locus_tag="VYN42_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1462803.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(645..1457)
                     /gene="folK"
                     /locus_tag="VYN42_001763"
     CDS             complement(645..1457)
                     /gene="folK"
                     /locus_tag="VYN42_001763"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1462804.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(1500..2054)
                     /gene="folE"
                     /locus_tag="VYN42_001764"
     CDS             complement(1500..2054)
                     /gene="folE"
                     /locus_tag="VYN42_001764"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1462805.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(2035..3357)
                     /locus_tag="VYN42_001765"
     CDS             complement(2035..3357)
                     /locus_tag="VYN42_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1462806.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(3359..4333)
                     /gene="folP"
                     /locus_tag="VYN42_001766"
     CDS             complement(3359..4333)
                     /gene="folP"
                     /locus_tag="VYN42_001766"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1462807.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(4428..5135)
                     /locus_tag="VYN42_001767"
     CDS             complement(4428..5135)
                     /locus_tag="VYN42_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462808.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(5188..6606)
                     /locus_tag="VYN42_001768"
     CDS             complement(5188..6606)
                     /locus_tag="VYN42_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1462809.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            6796..7608
                     /locus_tag="VYN42_001769"
     CDS             6796..7608
                     /locus_tag="VYN42_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1462810.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7947..8966
                     /gene="adhP"
                     /locus_tag="VYN42_001770"
     CDS             7947..8966
                     /gene="adhP"
                     /locus_tag="VYN42_001770"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1462811.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2692 a         2081 c         1760 g         2526 t
ORIGIN      
        1 gtaactgaaa gttatataat caagttaatt tgggaattta cctattaact tcgatagatt
       61 tttgggaatt tttttccttc tttttccctg tagttaaaat ccttttcaaa aaatcacctt
      121 ttcttgattt ttaatcctat ttgctgtatg ataagggaaa agaaagggga cagagatatg
      181 gcttttacca atactcacat gcggtctgct agttttggca ttgttaccag cttgcctgat
      241 gacatcattg actctttttg gtatattatc gaccatttct taaaaaatgt ctttgaattg
      301 gaagaagaac tcgagtttca attgcttaat aaccaaggaa agattacctt ccacttttca
      361 agtcaacacc tccctacagc cattgatttt gactttaacc atcctttcga ccctcgttat
      421 cccccaagag tactggtttt agacatggac ggtagagaaa ctatcctcct cccagaagaa
      481 aatgacctat tttaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagc
      541 tgtacttgag tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtataa
      601 aaactctagc cttcagttgc aagtgactga aaactagagt ttttctattt tttcaaagca
      661 tcatacaagt tgcggatcgg ttgttttaat atcggatgga taaaatgagg cgcaatttcc
      721 tgtaaggact caaggacaaa aaggcgttcc gctatgtaag gatgaggcaa tatgaggtcg
      781 tctgtataaa ggatctggtc ctccacaaag agcaagtcca aatcaatcaa acgaggtccc
      841 caatgcactt ctctcacccg tcccagctct gactcaatgg ctaacaaggt ttctaacaag
      901 tcttgtgctg gtagccaggt ttccacctca accacttgat tggcaaagct atcctgctcc
      961 actccacccc aaggctccgt cgctaagaca ctggactctt tgagaatatg gatgccacga
     1021 gctcgcagtt tgtcaatggc ttgcttcaag tttgcttgct tatctcccat attgcttcct
     1081 agggcgataa aggctcgttg cttgcggcga tgaatggtta ccgagcaagt atctagtgac
     1141 aaatgcaccg gtgcccaagg ttttttcagt tccaacttca tttcttggac aagaggataa
     1201 gactcaaagg tacgttccac cagtttatag gctaccgttt caatcaaatc ttcactcgtt
     1261 tcctgaaacc aagtcgtcca ctgctgacac aattctccgt aatggacaga ggctgttaaa
     1321 tccaagtctg tagctgcctt ggtcatatca taggatagga tggctgaaac gacaaatttc
     1381 tgccccaatt ctttctcact aggaaaaaga ccatgatagg caaacatttc caaatcctta
     1441 atctgcagtt gatccataat gattcctttc tagaaaaatc cgcttgaaac ggattctttt
     1501 tatagcccca ttaaacgata agcttggtcg cggaggtcct tatctgtttc aaatagacca
     1561 cgagctactg tcgtcaaggt tgcagtgcct ggttttctaa caccacgcat actcatacac
     1621 atatgttccg cctcaatgat aacaaaggct cctttagcac ctagatagtc catcaaggca
     1681 tcggccactt cgatattcaa acgttcttga atttgtggtt ttttcgaata aacttcaacc
     1741 gtacgggcta acttagacaa gcctgccaca cgaccatctg gaatgtaggc aatgtgcgct
     1801 ctaccataaa atggcaagaa gtggtgttca cacatggtat ggaaaaagat atccttttct
     1861 accaccatat tatcgtcaat aatttcaaag gattttgaca aatgttcctc tgctgtttga
     1921 ccaagacctg aaaaaatctc ttgatacata cgggctacac gagcaggtgt ttcctgcaaa
     1981 ccctcgcgat tagcgtcctc tcctacagcc tcgataatca tttttacagc tgcttcaatc
     2041 ttttgtgtat ccattctcgt tcttcctctc catcagatag gccctcactt ggctcaagaa
     2101 atacaaggaa cctgtgacaa tcctaactgt ttgtttctct tcttttttat ctgtcaaatt
     2161 ctgctctaga aaatcatgcc aatcttggta gctgagattt ctagacttag ctgcctcttt
     2221 cagcacgctt tcatccgtcg cccgactatc cgcaaaatgt gttagagtaa gctcggtatc
     2281 tggcatggct cccagcaagt ccaacatatc ctccaaggcc ttggttttga tacaagtgaa
     2341 gaggatttcc ttatgataat ccgcaaaacg ttcttgcaag gttaccaaca aggccttgat
     2401 agcatgggga ttgtgggctc catccaaaat catcaaggga tctcttgaca cgatttccaa
     2461 acgccctggc caacttgttt cttccaaggc ttgaccaaga aagtcattgc ttgctagctc
     2521 tcgaccatct tcttgacaaa aagtatcaag taaagctatg gccatcccag cattctctat
     2581 ttggtacaaa ccaagcaggc tagtctggaa gcgaccttgt ctgacagcac ttgtatagtc
     2641 aaagacttcc cctgtcacca cactttcttg atgacgaacc tgataatctg tcccgtaggc
     2701 aagtctcggc gaatctttcc cttccgcaat gcggtcaatc acagtcaagg cttctggagc
     2761 aatacgccct gttaccaagg gcatcccttg tttgataata cctgccttct gctctgctat
     2821 ggcctccaag gtgtcaccaa gtagggccac atgatccaag ccaatagttg taattcctgt
     2881 caaaatgggc tgacagacat tggtactatc caaaagtcca cccatgccaa cttccatgat
     2941 ggccacatct acttgctctg aggcaaagta gtcataggcc agggctgtga taatctcaaa
     3001 ctcggttgtg ccctgtaaat tggcgaccgc ttctccctcc agcaaagact gatagtctgc
     3061 catgagagct tctagcctcg cttctgagat cgattcccca ttgatgctaa tctggtctgt
     3121 gtaatgaatg agatagggcg agctaaacac gccaactctc agccctagct tttctagcat
     3181 ctttttcaaa aaagcaatag tcgagccctt gccgttagtc cctccgatat ggaggacctt
     3241 gagtttgaga tggggattgc cacgcaaagc taacagttcc accattcgtt ccaagccaaa
     3301 atgcggttga tccgtccggt agttagcaat ccactgattg ttttcaattt ctttcatctt
     3361 atttatattg ctttaaatct aaattttccg cttcatcagc cagacgaatg gcagatgcaa
     3421 tttcaactgc catcctgtga ctagctacgt catgcacgcg caccacttct acaccctgtc
     3481 tcgcagcgat actagttaca tgagccgaag ccgtgtcccg atttcggaaa ccaagctctg
     3541 tctcaggatt gacttcaaac ccactttctt caaggatatt gatgacaaat cgcttgcgcg
     3601 acactccgag aaagattgga tagcccttct gatgtagttt atccagatcc cgtaaaagga
     3661 ggagattttc tttcttggtc agaccaaagc caattcctgg atccaacagg atattttctg
     3721 gtgcaatacc agcttctgcc gctctcgcta gtgctcgttc aaagaaagcc accatcaagt
     3781 cttcgattgg caatgtttca aagtcagcta actcttctac tgtaaaagtt tgattaaatc
     3841 caaaatgagg gaatatgagc gagctagggt gttgaggtcg cgccataact ggattaaaca
     3901 tgatgaccac ttgcgctctc gcttcagcta ccacatgagc cattttttca tcgcccatga
     3961 gaccagtgat atcattaact agattggcac cagcagccaa agcagcctct gctacttgac
     4021 tcttccaagt atcaatagag atgaggacat cactttcctt gcgaatcgct ttgatcactg
     4081 gaacaacacg ctggatttcc tcttctatct caacatagct actgcccggc cgagtcgatt
     4141 ctccgccgat atcgagcata ctggctcctt ctgctatcaa tttacgagcc tgctggagtg
     4201 cctgctcaag agcaaaaaat tgaccaccgt ccgaaaagga gtctggggtt acattgataa
     4261 ttccgcaaat aactgtcttt gcatgattgg ctttacttga catatcggtc actccctcaa
     4321 ggattttcat catattattt ttctatttta ccataaaaag aaaaagatgg acacgattgc
     4381 attcatcttt ccctagtgga aagaggtcgg ttcctacata aaaactttta aacagaaatt
     4441 cctaatgtcc gactcataat caccacaaga gccaacaaac agaaagcaat cccattaaca
     4501 atcatgtgaa gcaagatcga catttccaaa cgttgggtct tgtaggccgt ccaagataga
     4561 actgtcgaca tacctccata aatcaataaa gaaggtaaat tacttggttg atgcaataaa
     4621 gcaaacacaa tcgtaccgac tacaaatccc aagttctcct tgcctcggaa aatcttttta
     4681 ggaacaatcc cacggcacaa gatttcctca caaatcggag caagcaaggc tagcaagaag
     4741 aaactggaaa tcaacgaact attttgaacc atatcgttaa tctgagactg gttagctgtt
     4801 gtcgtctcat ttgacagttg caacaagata gaaccaagta tatttgaccc gacaataact
     4861 aaataactca agcccaaacg tgccaaatct ttagctctaa aaaaagaaaa attaaaacta
     4921 gctaacttgg ttttacgagc tcccataata aatagagcca gaaccacaat tgaaaggcca
     4981 gcaactatca gccctgactg tagcagggct acttctttta aagtcaaaat agaggtaacc
     5041 actaggggaa cctgatataa aaggacggca agtaaaaaga ccaaaatcca gcctgcacga
     5101 ttcaacaatt ctttccacat atttttctct ttcatcacct atctcctttg tattaaaaaa
     5161 ggggggaaat ccccctgggt cattctatta taaggccatg ctgatgtagt taaggataaa
     5221 caaggcatcc aaaatccaaa tcatggcatg aacatcttta acttgacctt tgacaagctt
     5281 agtcaaagtg taagtcaaga aaccaactgc aatcccttga gtgatagagt agctgaatcc
     5341 cataaagata gatgtgaaga aggcaggaac tgcttcagac atatcatccc aatggatatt
     5401 tttcaagcta ccaagcatca taatcccaac gataatcaag attggagctg tagccgctgt
     5461 tggtacgatc gctagaagtg ggctaaagaa gcttgaaatc gcaaaacaga tagctacaac
     5521 caaggctgtc aaaccagtac gtccacctgc accgatacca gcagcagact caacataagt
     5581 cgttacgttt gaagtacctg caatggcacc gactgtcgtt ccaatcaaat cagagtaaag
     5641 agccttatcc aatttggctg attggtgatt ttcaccattt gtcgctacaa taccaacttt
     5701 ttcacctgta ccgatcaagg taccaattgt gtcaaaaata tctgtcaatg agaaggcaag
     5761 aatggccatc agagtttcag gcaagcgagc tgtatctgaa accaaagctc ccaatccttc
     5821 tgaaccaaga gctgcaccaa agattgtctt caaatcttca aaagctgcac caacatggtt
     5881 attagcaaaa tcgatactag acaaatcaac caaaccaact gcaatagcaa gaacagttgt
     5941 tgtcaagata gagagaataa ttcccccttt aatccctttg atgacaaaga agatagtaat
     6001 ggcaagtcct gcaagagcca ctaaaacagc tggattatta aagctgacca atcctggaac
     6061 tgctgaagag tttgctgcaa tcgttgcttg agctttgtca gccccttctc ctacaacagt
     6121 atagttgcct ggatcaatcg tgaatttcaa aagtccagca ttcttaatcc ctacataggc
     6181 aaggaagaca ccgataccag ctgaaatagc tgagcgaaga gcattgggaa tcgattcaat
     6241 gatcatttta cgaacatttg tcaaggtaat aatcaatgaa ataatcccac agatgaagac
     6301 catagctagg gcttcttgcc aagaataacc aagcccgaat acaactgtaa aggtaaagaa
     6361 ggcattgagt cccatacctg gcgcttgggc ataaggtaag ttagcataaa aagccatcat
     6421 caaggtaccc gctactgcac caataatcgt cgctaggaag acgccctgag caggcattcc
     6481 tgtttgtgaa agtatttgtg ggtttacaaa gagaatatag ctcattgcaa agaaagttgt
     6541 taaaccagcg agaacctctg tacgaacgtc tgtaccgttc tcttttagtt taaataattt
     6601 gtccatcatc aatctccttt taatttttac gaacaataat agaattatat catttatcat
     6661 tcactttttc aatgtctttg tttgatttgt ttaagaaatt aatccaattt cattttttgt
     6721 ttggaatctg cttttctgcc tgctttctgt tataatagaa gacatcttat ctgaaaacac
     6781 actagaaagg tccatatgac gaaaaaaatt attgcagttg acctggatgg aaccctgctc
     6841 aactcagaca gtcaaatttc tgactttacc aaaagaacca tcaaaaaagt tgctgaaaaa
     6901 ggccatcagg ttattattac gacaggtcgc ccttaccgta tgtcaaaaga tttttaccgt
     6961 gaactgggct tagacactcc tatgattaac ttcaacggat cccttactca tttaccagac
     7021 caagtttggg attttgaaaa gtgtttgact gtagacaaaa aatatctgct agatatggtt
     7081 caacgttcag aggacattca agccgatttt atcgctggag aatatcgtaa aaaattctac
     7141 attacaaatc ccaatgaaga aattgccaat cccaaactat ttggtgtaga agctttccag
     7201 cctgaagatc aattccagcc tgaattggtg accaaggacc ctaactgtat cctcttgcag
     7261 accagagcca gtgacaaata tgccttggca aaagaaatga acgccttcta ccagcatcaa
     7321 ctttctatca atacctgggg aggtccgctc aatatccttg aatgtacccc aaaaggtgtc
     7381 aacaaggcct ttgctttgga ctacttgctc aagataatga atcgtgacaa aaaagatttg
     7441 attgcctttg gagatgaaca caatgatacc gaaatgctcg cttttgctgg gaagggttat
     7501 gccatgaaaa atgccaatcc agagctactc ccttatgcag atgagcaaat ttcccttacc
     7561 aacgaccaag atggggttgc caaaacccta caagacttat tcttataacc tatactgata
     7621 ctcaatgaga atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcactgctt
     7681 tgaggttgta gatgaagctg acgtggtttg aagagatttt cgaagagtat gaccagcttg
     7741 caagctggtc tttgtgctct tttcacagtc tcatcaacca gttaatcgat tgttctactt
     7801 tttgtctcca aaaccttgga aaaggctttc ttttgtgata tacttcacat ataaatacaa
     7861 gagagctcgt cacactcgac tctgttgaca aaaaatcaat ccagtcccgt tgtccctgtt
     7921 ctcggtcaat atcaaggagg atagctatga aagctgttgt tgtaaatcca gaaagcactg
     7981 gtgttgctat tgaagaaaaa gtactccgtc cacttgaaac tggggaagca cttgtagaag
     8041 ttgaatactg tggtgtttgc cacaccgacc tccacgttgc tcatggtgac tttggtcaag
     8101 tcccaggacg tgttcttggg cacgaaggta tcggtatcgt taaagagatt gctccagatg
     8161 tgaaaagcct taaagtcggt gaccgcgtca gcgttgcttg gttctttgaa ggatgtggca
     8221 cttgcgaata ctgtacaact ggtcgcgaaa ccctttgccg tacagtgaaa aatgctggct
     8281 actcagtaga cggtggtatg gctgaacaat gtatcgtaac tgctgactat gctgtcaaag
     8341 ttcctgacgg acttgatcca gcccaagctt cttctatcac atgtgctgga gtaacaacct
     8401 ataaagctat caaagaagca aaagttgaac caggccaatg ggttgttctt tacggtgctg
     8461 gtggacttgg taacctcgct gttcaatacg ctaaaaaagt attcaatgct catgttatcg
     8521 cagtcgatat caacaatgac aaacttgccc ttgcaaaaga agtaggcgct gacattgtga
     8581 ttaacggcct cgaagttgaa gatgtagctg gactcattaa agaaaaaact gatggaggag
     8641 ctcattcagc tgtcgtaact gctgtgtcta aagttgcctt caaccaggct gttgactcca
     8701 ttcgtgctgg tggtcgcgtc gtcgctgttg gtcttccttc tgaaacgatg gaactcagca
     8761 tcgttaaaac agtcctcgat ggaatccaag tcatcggttc tcttgtcgga actcgtaaag
     8821 acttagaaga agccttccaa tttggtgcag aaggtctggt agtcccagtt gttcaaaaac
     8881 gtccagtaga agatgctgtt gccattttcg acgaaatgga aaaaggccaa atccaaggac
     8941 gtatggtact cgacttcacc cactaatcta atagaaacct attttaaaag ttggaagctt
     9001 cttccaactt ttttatatta aattttaaat aagaattcaa gattactcct caaaaactc
//
LOCUS       DAVLUM010000077         9056 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLUM010000077 DAVLUM010000000
VERSION     DAVLUM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.077"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(390..1238)
                     /gene="dprA"
                     /locus_tag="VYN42_001771"
     CDS             complement(390..1238)
                     /gene="dprA"
                     /locus_tag="VYN42_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1462812.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1334..2023)
                     /locus_tag="VYN42_001772"
     CDS             complement(1334..2023)
                     /locus_tag="VYN42_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1462813.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(2035..2913)
                     /locus_tag="VYN42_001773"
     CDS             complement(2035..2913)
                     /locus_tag="VYN42_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1462814.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2903..3772)
                     /gene="licA"
                     /locus_tag="VYN42_001774"
     CDS             complement(2903..3772)
                     /gene="licA"
                     /locus_tag="VYN42_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1462815.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGTDEK"
     gene            complement(3789..4811)
                     /locus_tag="VYN42_001775"
     CDS             complement(3789..4811)
                     /locus_tag="VYN42_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1462816.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMKVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4816..5523)
                     /locus_tag="VYN42_001776"
     CDS             complement(4816..5523)
                     /locus_tag="VYN42_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1462817.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVLHAEDLVDKYLPLHKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIKLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5878..7365
                     /gene="tacF"
                     /locus_tag="VYN42_001777"
     CDS             5878..7365
                     /gene="tacF"
                     /locus_tag="VYN42_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1462818.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7375..8178
                     /locus_tag="VYN42_001778"
     CDS             7375..8178
                     /locus_tag="VYN42_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1462819.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8180..8989
                     /locus_tag="VYN42_001779"
     CDS             8180..8989
                     /locus_tag="VYN42_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1462820.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2840 a         1823 c         1520 g         2873 t
ORIGIN      
        1 cagtctatag tgtattgaat ctataacagt acaccttggc tgctaaaata tttctataaa
       61 ttaatttgac tttcctgata gagttgttca catcttattt caattcacta tactttccct
      121 tatactcaat gaaaatcaaa gcgcaaacca ggaagctagc cacaggttgc tcaaaatact
      181 gttttgaggt tgcagatgga agctgacgtg gtttgaagag attttcgaag agtattatat
      241 gagaaaaatc ctctactcta ctaatccact tagaaaaaac gcatattatc aagtgttaaa
      301 aacttgctaa tatgcgtttt attatggaaa tgttgggttc attttctctt aaaattgatt
      361 ttttcttaga attctagctt aggtcatttt taaaattcaa attccgcaag aacatcttgc
      421 ccactggtga ccaattttgc tccttcttga atcaaatgat ggcaaccgtc tgatagtcca
      481 tctaaaatgc taccaggaat agcaaagaca tcgcgtcctt cttccattgc tcgctcacac
      541 gtaatgagac tacctgaacg catcttagcc tctgctacaa tcacaccacg acaaagtcca
      601 gcaatgatgc gattacgggc aggaaaatga aatttcagag gttgttcgcc aggtccatat
      661 tcacttaaaa ccaaatggtc attgccgatg tagtcttgca agcgtttatt ggctttagga
      721 taaaacacat ccagtcctgt tccaatcact gcaatggttt ttccgccatt ctgaagagct
      781 gccatatgag ctgctgtgtc aatgcccttg gccagaccac tgacaataac cagttcattt
      841 tccaagcctt gaatgacttt ttcaactgat ttagctccct gtttgctaca agcacgactg
      901 cccacgaccg ctaccttcgg gaatttcagg aggtcaagat ttcccttgta aaataaaagt
      961 acaggcgcat catatatttc actcaaatcc caaggataac agtcatctaa aatagagaaa
     1021 gatggaaatt tttgaaactc tttcgacaaa tgcgcatcgt ctatctgaaa ataacgttcc
     1081 ataaaaacgg ctggattacg gcaacctgat atatctgcaa tatcacccaa caaaagctcc
     1141 tgatcaacat tttcaccgta ttctagcact ttcaaaatct gttgattggt caaacctgat
     1201 ttttttaact tatagatttc atagtttgtg attttcataa ataactccat ttctttttct
     1261 actcatctat ctattcgtaa aagttcgtaa aaaatcaaaa aacatccgac tattttgtca
     1321 gatgttggaa tctttaattt tcgtttttaa gaatttcttc taatttacga tagtcttgga
     1381 cactatcgat ctcataaatg ctattgcctt ctaattcttc aacatagaca tctagctctt
     1441 tgatattatc cttaaccata ttgtcccaat agagatcaac aaattcacca cttgcataag
     1501 ccttgtcgat aaagctgaca atcttttctg cagttggagc atcccagaag gatacaccac
     1561 taaggatgcg acctgccttg ctatcaacaa taatgtcttg aaccttgtag tcatctccat
     1621 agaccaagaa ccattcgttg gtacaatctt cacgataaac actaaaataa gtcgaacgtg
     1681 tcaaatcatt gcggaacata tttttaaaga gataattgtc agcatcaata acatagctgt
     1741 tggccaattc ttcttttaca agatagagag agtaaaagtt attgtagtca gcgtatttat
     1801 cattgaaaac gaggcgaaca ccgtattttt cttttaagta atcgaattgt tctttaagat
     1861 aaccaacaat gatgatgatg tcattgattc ctttttcttt gagaaactca atttggtatt
     1921 caatcaaagg tttttgatta acctgaacca aggctttagg ggtattttca gtcataggac
     1981 gcaagcgagt tcccaatccc gctgctaaga taatggcttt cacacgaatc tcctttattc
     2041 tttaataata atataaactc cagcaatgac gacaagtgac gtcataatgg tcagcatatc
     2101 tagcggtgca cccaaaaaaa caactgcaaa caagaccgtc catactacat agctcacgtt
     2161 caagcctgta gccttggctg gttgcaagcg attgatagcg atataataag ccaagtagga
     2221 aatcatatca aaggctgcaa aaacaatcat gagacctagc aattgtccat tggctactgc
     2281 agtaaatgac tgatgagaga agagcacaat cacaagatag gacaagaacg aagtcacttg
     2341 acggattaag agggcttcga tttcactcag ttcactttcc atagcaaagg agctaagaac
     2401 actctcactt ccccatgcaa tagcacaaac caaagcacag agaatcccaa tgtagaagga
     2461 attaacctgt tcaaccttat aggtctgggc aataatccct ccaataatca agacaatccc
     2521 aaatacagta tttttcgaaa tcttgtgctt caaaaagaag aaagccaata gaactgaaat
     2581 cgcagggtaa atagccgata cagatgaagc taaagaactt ccgatatact taactgcata
     2641 aagattggcc tgcataccga tagggcctgc tagcaaggct ccgatgataa cactgacatt
     2701 gcgaatattt aagaaaattg agaggcgaac tttcccttct tttaccaaga gaaaagctag
     2761 taagataaag atgctcaaaa aatcatgagc tgcagccacc acaaagggtg acaaatctgt
     2821 aaaaatcgaa aagatataag cactaaccgt tagacccaag ccccagaaaa tacctgagag
     2881 aaggccaaaa ggaactccgt ttttactttt catctgttcc tccataagaa gccaaacctt
     2941 taacagctct ttggtaacga ttcacaccat agtaaccaaa atctgcacct tgctcttcct
     3001 tatagacagt ccatagactc caaatagtat cttgtaaaat tttataaata gcaatctttt
     3061 catgagaaac cggtgtttgg tcactctcat agtgagataa gaaagtttct tcctcttggg
     3121 aagtgaattc agactctaaa aagagggcag ccaaatccca cattggatca ttcattgatg
     3181 aatattccca gtcaatcaaa taaagtcgtc cttgaggtga ttcgataaag ttttcaggca
     3241 ccaaatcgat atgacaagat tttctgtcaa cacctaagtc agccagtctt ttctctaagg
     3301 agaagactgc atttctaaca gattcatagt tggcataagg aatttgttct tcaatcaagg
     3361 attcgtattt tttgatttct tcaaaaggag caaattctcc tcttaattcc ttagcagatg
     3421 tatgaatagt ttgtaatatt ggagcaattt tgtcgaactt ggtcttgatt gacgttgaat
     3481 caagcgtaat cgcagattcg atatactcat ttactttgat gccagcttca atatcaaaaa
     3541 gataattttt tacatctaag cctaaatcct ttagtagttc aagattgtac ttttcatctt
     3601 gtcgattgat aagcttttct gtccctttac caaagaattt aacaatgtat tgcttatttg
     3661 ttgttttggc caaatagttt tgattggtca ttccacctag ttgttcaaca ctgaggactt
     3721 cttcttcttg actaagtaag gaagaaattt tttctttaat gattttctcc acaattaacc
     3781 tccaggactt atacttccca cttaaacact gttttaaagg ctgtatttaa atcggttgca
     3841 aagacacggt gaatatcttt aatttctctt acaggttctt ctagataaag gatattttta
     3901 agacgattgg caaatttctt gactttcatc atttggatag cattttcaaa atcaatgcga
     3961 ccagaacgag atgacccaac caagagcaag cccttttcta aggcatcgcg agtattgaga
     4021 ttgactttat attcgctaac tcccatcatg agaattgttc cctgaggacg aatgtagcga
     4081 atcaagtcat taatagctgg tccagtacca tcaccaccac aacattcaaa agcatggtca
     4141 aaggccaact cttcaggaat attatccgta atatagcatt ctttggcaaa tgagaagagt
     4201 tccaactttt cccaatgacg accaataacc acaatctctg cttctggcaa agtataattg
     4261 ataatattgg caaccacaaa agctaaactt ccatctccaa taacggcgat ccgctcccgc
     4321 ttgctatgag caagagtcaa tagacgattc atagcgtgca tgcccacact gacaaactct
     4381 gtaatagctg caaccgtatc ttcaatagca tcataagcca ccacacgatc tttagggaga
     4441 gaaacaaact ctctcataaa gccatcaaat ccactagaca agaaatgggt ccctgtcatg
     4501 tagttttcat agaattcttc atcactctgc ataggagact gattgggaat catgacaact
     4561 ttttgaccaa cctcgtaggt tcctgtcggg tcagaaatga cggttccaca tgactcgtga
     4621 atcattgcca ttggaagctt tttattcaaa atcttgggat cacgttttcc ctggtagtaa
     4681 cgctgatccg catgacagac agccatgtag ttgggacgga taaggatatg attctcttgg
     4741 tcaatagcct cttcctgata tttgacattg ataaacttag gtttagttag ttgataaatt
     4801 tgattaatca ttttactagt ctttctcaat catacttttt gcaatcttca aatctgttac
     4861 ggttgtaatc ttcagatttg agtattcgcc tttggccaag gctacatctt ttcctttgat
     4921 cacaaagatt ttacatgcat ctgtcaagat ttccttctct tcatcagaaa gagatccata
     4981 aaggtccatg aagtccttgc aacggaatgt ttgaggtgtt tgtccctgat agaggtgagc
     5041 acgatttgga atacctgtaa tgaattgacc attggtactt tcaacgatag tatccactgc
     5101 ttctactact gtatccactg cgtcatgatt ttgagcaagt ttgatactgt cttgaatcat
     5161 gcgaagcgta ataaatggac gaacagaatc gtgggtaaca acgatatcct ctggagtaag
     5221 cgggcgataa gcatcaatgg cttcaatgat gttctcaata cttgtattgc ggtcagcacc
     5281 accctttgta atgataatac gttccttatg aagaggaaga tatttatcta caagatcttc
     5341 tgcatgtaaa acccagtctc catgaacacc aactacaatt ttttcaatac ttggttccaa
     5401 gacaaatttt tcaattgtat gaatcaaaat aggtcgatca cctagctcta aaaattgttt
     5461 tggcaagtta ctgattccca tgcgtgtgcc agttccaccg gcaagaattc ctgcataaat
     5521 catctatttt ctcctttgtc ttactaaaaa acttattctc tctattatac cacaatctag
     5581 tcctatatac cacaatctag tcctatcatg aaagaaatac tggtcctccc cttctagaat
     5641 aggagaatta tgcagttcta ttattcaaag aaacaagcct atttctagta atgactagga
     5701 attctgtagc aattactaat aaatgactgc gaaattttag agtcctttag aataatatac
     5761 tttccttaaa gaaaacttaa aatttaagat ttgaaacttc aaagtgatta cttgacttac
     5821 tgcccttcat ttcttattag ctaactttat gatataatga aaaacgaggt aaattgaatg
     5881 aaaagtataa aattaaatgc tctatcttac atgggaattc gtgtcttgaa tattattttt
     5941 cccatcctaa ctggaaccta tgtcgcgcgt gtcttagacc gaactgacta tggttacttc
     6001 aactcagtcg acactatttt gtcatttttc ttgccctttg caacttatgg tgtctataac
     6061 tacggtttaa gggctatcag taatgtcaag gataacaaaa aagatcttaa cagaaccttt
     6121 tctagtcttt tttatttgtg catcgcttgt acgattttga ccactgctgt ctatatccta
     6181 gcctatcctc tcttctttac tgataatcca atcgtcaaaa aggtctacct tgttatgggg
     6241 attcaactca ttgcccagat tttttcaatc gaatgggtca atgaagctct ggaaaattac
     6301 agttttctct tttacaaaac tgccttcatc cgtatcctga tgctggtctc tattttctta
     6361 tttgttaaaa atgaacacga tattgttgtc tatacacttg tgatgagttt atcgacgctg
     6421 attaactacc tgattagtta tttttggatt aaaagagaca tcaaacttgt taaaattcac
     6481 ctaagtgatt ttaaaccact ctttctccct ctgacagcca tgttagtctt tgccaatgcc
     6541 aatatgctct tcactttttt agatcgcctc ttcctcgtta aaacagggat tgatgtcaac
     6601 gttagttact ataccatagc tcagcgaatt gtgaccgtta tagctggggt tgtaacaggt
     6661 gcaattggag tgagtgtgcc tcgtctcagt tactatctgg ggaaaggaga caaagaagcc
     6721 tatgtttctc tggttaatag aggtagtcga atctttaact tctttatcat tccactgagt
     6781 tttggactca tggttttagg accaaatgcc atcctacttt acggtagtga aaaatatatc
     6841 ggaggcggca tcttgacctc tctcttcgct tttcgtacga ttatcctggc cttagatacc
     6901 attcttggtt cccaaattct ctttaccaat ggctatgaaa aacgtatcac agtctataca
     6961 gtctttgctg ggctactcaa tttgggcttg aatagtctcc tctttttcaa ccatatcgtg
     7021 gctcctgaat actacttact gacaactatg ttatcagaga cttctctact tgttttctat
     7081 atcattttca tccatagaaa acaactcatc cacttgggac atatctttag ctatactgtt
     7141 cgatactctc tcttttcact ttcctttgta gcaatttatt tcctgattaa tttcgtgtat
     7201 cctgtggata tggtcattaa tttgccattt ttgattaata ctggtttgat tgtcttgcta
     7261 tcagctatct cttatattag tctacttgtc ttcacaaaag atagcatttt ctatgaattt
     7321 ttaaaccatg tcctagcctt aaaaaataaa tttaaaaaat cataggagtt taaaatgaaa
     7381 caactaaccg ttgaagatgc caaacaaatt gaattagaaa ttttggatta tattgatact
     7441 ctctgtaaaa agcacaatat caactatatt attaactacg gtactctgat tggggcggtt
     7501 cgacatgagg gctttatccc ttgggacgac gatattgatt tatccatgcc tagagaagac
     7561 taccaacgat ttattaacat ttttcaaaag gaaaaaagca agtataagct cctatcctta
     7621 gaaactgata agaactactt taacaacttt atcaagataa ccgacagtac gactaaaatt
     7681 attgatactc gaaatacaaa aacctatgag tctggtatct ttatcgatat tttccctata
     7741 gatcgctttg atgatcctaa ggtcattgat acttgttata aactggaaag cttcaaactg
     7801 ctgtctttca gtaaacataa aaatattgtc tataaggata gccttttaaa agattggata
     7861 cgaacagcct tttggttgct ccttcgacca gtttctcctc gttattttgc aaataaaatc
     7921 gagaaagaaa ttcaaaaata tagtcgtgaa aatgggcagt atatggcttt tatcccttca
     7981 aaatttaagg aaaaggaagt cttcccaagt ggtacctttg ataaaacaat cgatttaccc
     8041 tttgagaatt taagccttcc tgcacctgaa aaatttgata ctattttgac acaattttat
     8101 ggagattata tgaccctacc accagaagaa aaacgcttct acagtcatga atttcacgct
     8161 tataaattgg aggattagga tgcaatattt agaaaaaaaa gaaattaaag aaattcaact
     8221 agccctgctg gactatattg atgagacttg taagaaacat gatattcctt attttctcag
     8281 ttatggaacc atgcttggag ccatccgcca caaaggtatg attccttggg atgatgatat
     8341 tgatatttcc ctttatcgtg aggattatga gcgtttactg aagattattg aagaagaaaa
     8401 tcaccctcgc tacaaggttc tttcctacga tacatcttct tggtacttcc ataatttcgc
     8461 atcgattttg gacacttcta ctgttataga agaccatgtt aagtacaaac gtcatgatac
     8521 cagccttttc atcgatgtct tcccaattga tcgatttaca gacttgagca ttgtcgacaa
     8581 gagctataag tatgtggccc ttcgtcaact agcttatatc aaaaaatcac gagcagttca
     8641 cggtgatagc aaactaaaag attttcttag attatgtagc tggtacgctc tccgatttgt
     8701 caatcctcgc tacttttaca agaaaattga tcaactagtc aaaaatgctg taaccaacac
     8761 tcctcaatat gaaggaggag ttgggatcgg taaggaaggg atgaaagaaa tcttcccagt
     8821 tgataccttt aaagaactga ttttaactga gtttgagggc cgtatgttgc ctgttcccaa
     8881 aaaatatgac caatttttaa cccagatgta tggcgattat atgacaccac catcaaaaga
     8941 aatgcaagag tggtatagtc atagcattaa agcttatcgc aaaaactgat tgaggggtat
     9001 tatacaaact actaagatag aggttattca aaaacataat tttagtagaa aatgaa
//
LOCUS       DAVLUM010000078         8848 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLUM010000078 DAVLUM010000000
VERSION     DAVLUM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.078"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            241..1236
                     /locus_tag="VYN42_001780"
     CDS             241..1236
                     /locus_tag="VYN42_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1462821.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            1262..1906
                     /locus_tag="VYN42_001781"
     CDS             1262..1906
                     /locus_tag="VYN42_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1462822.1"
                     /translation="MLRAGVLDANNGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEATVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(1949..3937)
                     /locus_tag="VYN42_001782"
     CDS             complement(1949..3937)
                     /locus_tag="VYN42_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1462823.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(3939..4697)
                     /locus_tag="VYN42_001783"
     CDS             complement(3939..4697)
                     /locus_tag="VYN42_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462824.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            5125..5316
                     /locus_tag="VYN42_001784"
     CDS             5125..5316
                     /locus_tag="VYN42_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462825.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(5670..5942)
                     /locus_tag="VYN42_001785"
     CDS             complement(5670..5942)
                     /locus_tag="VYN42_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1462826.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6001..6450)
                     /locus_tag="VYN42_001786"
     CDS             complement(6001..6450)
                     /locus_tag="VYN42_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1462827.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(6437..8566)
                     /locus_tag="VYN42_001787"
     CDS             complement(6437..8566)
                     /locus_tag="VYN42_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1462828.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            complement(8668..>8848)
                     /locus_tag="VYN42_001788"
     CDS             complement(8668..>8848)
                     /locus_tag="VYN42_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV1462829.1"
                     /translation="KMDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLN
                     TFDIMAWLKKGGNAL"
BASE COUNT         2700 a         1830 c         1714 g         2604 t
ORIGIN      
        1 tagaatagta cacctctact tctaaaacat tgttagaatt cgattttact gtcctgatcg
       61 atttgttctg ttcttgtttc attttactat atgttcgtaa atgaaagttc tataatgaag
      121 ttagccaccc agccctccta aaaattagat ggttcaacta gctgatagct cttgtaggca
      181 taagaaaaca cctctgtgtt atacttgttg ttcaaccaca aacacaagaa aggcacagag
      241 atgcaagaca attatactac aaaagccaaa catttgacaa tcgatagccg tcgcttaatc
      301 gaaagatgga aaaaagaagg gaaatcaaat agagaaattg cctctctgct tggaaaagct
      361 cctcaaacta tccacactga aatcaagcgt gggacagtcc gacaatgtct tggaaaaggg
      421 cgcttcaaag aggtttattc tgccgactat gctcaacagt cttatgaaaa caatcgcaag
      481 cgctcggtca ggaaatcaag cgtgaccaag gaactaaagg aaaagattct ccactatcat
      541 aaccaaaaat tttcgcctga aatgatggtg atggctaaag gggttaacgt gggaatttca
      601 accatttact attggattca tcatggaaaa ttggggttaa gcaaacagga tctgctttac
      661 cctagaaaag gaaaagcgct taagaaacag gctagcacca actttaaacc tgctggtcaa
      721 tccatcgaac agcggtctga agctatcaat cttcgcttgg agaatgggca ttatgagatt
      781 gatacggttc tacttacgag agcgaaaaac tactgcttgc ttgtcttgac ggatcgaaag
      841 agtagacatc agatcatccg attgattcca aataaaagtg ctgatgtggt caatcaggct
      901 ctaaaactca tcttaaaaca acacaagatt ctttccatca cggcagataa tggaacggaa
      961 ttcaatcgct tgtttgatgt attttctgag gagcacatct attatgcgca cccctatgcc
     1021 tcttgggaaa ggggaactaa tgagaatcac aacaggctca ttcgtagatg gttacctaag
     1081 ggaaccaaga aaatgactcc caaagaagtc gcattcatcg aaaagtggat taacaactat
     1141 cctaaaaaat gcttggacta caagtcaccc agagaagact tctggatggc taacttgaac
     1201 ttgaaattta gcgtcagaaa caaatcacga aattgattca aattttgcag gtcgtttaaa
     1261 tatcctgcgt gcgggtgttc ttgatgctaa caatggaatt atttccattg ctggtgtggt
     1321 tatcggagtt gccagtgcca cgagcaatat ctggattatc tttttatcag gttttgcggc
     1381 tatcttagct ggtgcctttt caatggctgg tggagaatat gtatccgttt caactccaaa
     1441 agataccgag gaagctaccg tttcgcgaga aaaactcttg ctagaccaag atagggaact
     1501 agccaaaaaa tccctctatg cttcttatat ccaaaatgga gaattcaaaa cttctgccca
     1561 actcttgact aataagatct ttcttaaaaa tccactcaag gctctggtag aggaaaaata
     1621 tgggattgag tatgaagaat ttaccaatcc ttggcacgct gccatttcta gcttcgttgc
     1681 ctttttcctt agaagtttgc ctccaatgct gtcagtgacc atttttccaa gtgattaccg
     1741 catccctgct accgtcctta tcgtcggtgt agcccttctt ctcactggct acacaagtgc
     1801 tagacttgga aaagccccaa ccaaaacagc tatgattcgg aaccttgcta ttggtctctt
     1861 aactatggga gttaccttcc tgctcggaca acttttcagc atttagaaaa caagaaatac
     1921 ctcgattttg aagtcgaggt atcttttttt acatttggac aatcttacga taacttcttg
     1981 aagtaatcat gaaaatcagc acataggcga tgaggaagat agcgcagata gacaaggtca
     2041 caatcaacat catagtcgta tccagtacac caatcacttt taaaatcaga ctaagcatat
     2101 ggtaggcaaa ggctagatgt aggaaggcaa agagcaaagg aaggaagaat acagttaaaa
     2161 cctgtttgtt gatggtttgc ttgatttgct tttgatctaa accgactttc tgcaagataa
     2221 taaagcgctc acggtcttca tatccttcag aaatttgttt gtagtagatg accagaacgg
     2281 ttccgaccat aaagataatg gataagaaaa taccgataaa gaagacacca ccaaagaggg
     2341 cactcatctg agcactagca tctgctagag tgctaccata cacatagtta ccttcagtgt
     2401 ttaattgagc attaaacttt tgtaagtatt tttcatactc ctcagcgacc ttgagttgtt
     2461 ctgcttcact ggcatttaca ttcataccac cgtaaaactg attatagata gccgaatctg
     2521 ggaattgatc caaaaaggct tgtaaatcag gtacaacaag gtaattgtaa tcagcagtca
     2581 aaatattaaa ctgatttgga acatggttga caataaaatc tttagtaaat tcttctttta
     2641 cagaaaattg atgatcattt agagttagag ctttctgttc tttaactccc tcattctttg
     2701 caaagagtcc gacctcattt cctgatagag acagtttttg accagtcata ttttcataat
     2761 ctttttggtc aaataccatg aaaactgttt ttggttggac acggttttgt cctttttcaa
     2821 aaatagttaa cttggttcct tcttgattcg caacagcaaa gtaagtgtaa cgaaatactt
     2881 ctttttcttt aatcttataa cctttgtcac ttgcaaactg gctcaagagt ttgtccaagt
     2941 cttctttttc aacattttgc cctgaaaccc caaaatcatg aggatttaga acttttttaa
     3001 agctttctga ggaattgaaa atgcttgtcg ctgctgacat ggttaccaaa accattgttg
     3061 acaagatagc gatggtggct agtccaactg catttttctt catacggaaa atcaagttag
     3121 aaacagatat gaggttattt ggttggtaat agtatttctt atttttcttt aagatttgga
     3181 ggaaaacggt aatccctgca ttaaacaaga gataagtccc aaagataacc agtaaaacag
     3241 ctatgaagaa ggttgttaag gctgtaagag gatcttttac cgtaagggca agataatagc
     3301 caattcctaa acttatggaa ccaagaatgg tttggagagg aaggaagcga ccttttttct
     3361 ctccactagc tttctcacga gagagctgga gggcattcat acgggcgatt cgaagggcat
     3421 tcaggaacat gaggcctagg aaaatcaaac cgaagacaac aagcactgta atgacaactt
     3481 tcgtctggaa ggtagcaacc agctcaacct tcaatttcat tagtttgagc aggaaagcga
     3541 aaattaactt gtcaaacaag gctccaatac cgatacccgc tccaacagtt agaatcccaa
     3601 ataccactaa ctccttaaag gtcatactga taagatgacg cttctccaag cccaacatgc
     3661 cataaattcc tagttccttg gaacggttct tcatgacaaa actattggca tagagaacga
     3721 taatggctga cgcaagggtg acgacaaaca taccaaatcc aagtgtagcc tgaatggttg
     3781 ttcctccacg gatttccgca atcttaggat tgaaggttag agagtaaaag agataggtga
     3841 cagtgactgc caagagaaca gccagcgcaa aaggatagta gagtttgcgg tttttaatca
     3901 agttcgatac cgctaactta ttggttaatc gaaacatact aattcacctc gcttgccatg
     3961 acagtcaagg tatcagagat ttcttggaac atctgacgtt ctgtcttctc tccacggtag
     4021 atttgattgt aaagaatgcc gtctttgata aagagtacac gtttagctct gctagctgct
     4081 gctgttgagt gggttaccat gagaatggtt tggccgcgct cattgatttc atcaaagaca
     4141 tcaagtaagg ctgcagatga cttggagtca agagctcctg tcggttcgtc cgcaaggaga
     4201 atttcaggtt ctgtgatgat ggcgcgggct actgctacac gctgtttctg accaccagaa
     4261 atctcgtaag ggtacttctc ttgtaattgg tttattccca gattctcagc tgtcaccacc
     4321 aatttcttca tcatctctgt aataggtctt cttgacaaga caagcggaag caagatattg
     4381 tcctttacag atagagtatc tagcaagtta aagtcttgga agacaaagcc caacttttca
     4441 cgacggaagc tagaggcctg tgaattttta atggttgcgg tgtcagttcc attcaagtaa
     4501 acctgaccac gacttggttt atccagcata gctagaatat tgagaagagt tgatttacca
     4561 gaaccagact cacccatgat ggcaacgtag tcaccctttt cgacggtaaa gtgaatatcc
     4621 ttgagggctt ctacttggtt gccctgaaaa cgtgttttat aaattttttg aacgtgtttt
     4681 acatctaaaa gtgtcatgag aatctccttt cttaatatcc catcaaatga aatgtagctt
     4741 gcatcatagt gcatcccagc tgaacgcgct caatttcttt gtgacttggt tttctagttt
     4801 tcttatgtaa gatttgtttc atgatgttac tcctttgttc tttatgagtc tagtttacat
     4861 caaaaaaaga ccgcttgcca taacctaacc ttacaaaaga gactttaatc ttacattttt
     4921 gtaagattgg gtgaaatata agcaaaatta cttagaaaat gatttgattt cctattttta
     4981 aagttgtaaa atataagtgt gaaaaggctt actttgaaaa ggaggaagcg ggaactaaca
     5041 ttttagtaag gttacctaga taacatacca ttcaatttaa cacttgcaag tcgttcaacc
     5101 tataaggaaa gaaggtgcgc tttaatgaaa cacaaagaac atatactcat cggacttctc
     5161 tatctgctct ctccattcat cggtcagctc ttagttgaac acacacactt tatcggtaca
     5221 gaatttaccg gcactgctta tgttatttgc tggttatcag ttgttatcag catccaccat
     5281 ttttccaaaa atgtattgtc tcagcagcaa aaatagatta aaaaactgag tttaaattac
     5341 tgcttttata ataaaatgaa ataagaacag gacaaatcga tcaggatagt caaatcgatt
     5401 tctaacaatg ttttagaagt agaggtgtcc tattctagtt ccaatccact atagtttgtg
     5461 gatgaagctg gcgaaatatt attaatacta ttcaaaaatc aaagtgcaaa ctatgtcaac
     5521 ttcacattgc cgactaaatt acagcctgtg gctggcttcc tagtttgcac tttgattttt
     5581 attgagtata aaagtaaaaa agctttaaat caagcagttt agactattga tttaaagctt
     5641 tttgcttatt ccaaatcttc tgtagaacct caccaaaacc agccttcatt gtcgtcaatg
     5701 gcttgggctt ctttgcgttt acgtgggcct gttccgtaca tttctgcttc gatttcttcc
     5761 ttggtaggca tgatagaagc taggatgata tagataatca cgccaagtcc aaagtttgca
     5821 actgtaaaaa tagcaaacaa gaaacgaact agggtaacat caaaattcca cttgtctgac
     5881 agacctgcca gaactcctga aatcatgcga ttgcgtctca ttttataaaa tttactgttc
     5941 atgatatttc ctctttctgc taggttagac atagtatatc acggggaggc tcggctttca
     6001 tcagtcctca ggctgattta tcagaagcaa tttacctcga caaagtccac agcgatagcg
     6061 tttggtatca atcctacgct tgcgctgata cctttgctgg caggattgac aacgataaag
     6121 cttgagtggt ttagagttgc tattgggcaa ggatggtaca aaccgtaatc catccactgc
     6181 tttcaaaagt tccttaaaat cccgatcctt gtgttgatag cccttccctt ggaaataaag
     6241 gtgataatga cagagttcat gtcggacaat tttcctaaaa acctccatac ccagtttctg
     6301 ataaaccttg ggattaaaat ccagatgccc atctttgggg aaaaatcgcc cacctgtcga
     6361 acgtagacgc ctattccact ggacatgatg gataaaagct ctcccgaagt cttctagtga
     6421 aacctgcttg acataatcag tcagtttcat ttggagcgag gagcgacaga ttaacttttt
     6481 cacgttcagt atcaattttc ttgacccaaa cggtcaccaa atctccaact gacaccactt
     6541 gactagggtg tttgataaac ttgcgactca tatgagaaat atgaatcaag ccgtcctcgt
     6601 gaatcccgat atcaacgaag gcaccgaagt caacaacgtt acgcacaaca ccttctagct
     6661 tctgacctac cactaggtct ttgatatcta ggacatcttg gcgaagcaca ggtgcgtcaa
     6721 aggaatcacg gaaatctcga cctggtttga gaagatctgc aatgatatct ttaagggttt
     6781 ctggaccgag gtctagctct tgagccattt ccttgactga aagggacttg agtttgcttt
     6841 gggcttcttc gtttaggtct ttaatatcta aacgtttgaa gagttcctta actgcagtgt
     6901 aattctctgg gtgaactcct gtattatcaa ggatattgct actttcaggg atacgaagga
     6961 aaccagcagc ctgctcaaag gccttggctc ccagacgagg aactttcttg atttgggcgc
     7021 gtgaagtgat ttttccttct tcctcgcggt atttgacaat attttcagag atagttttgt
     7081 tgagtccagc tacgtgtgaa agaagagctg ggctagctgt attgacattg acaccaactt
     7141 ggttaaccac tgtatcgaca acaaagtcca gactctcaga tagtttcttc tgactgacat
     7201 cgtgttggta ttgaccgaca ccaattgact taggatcgat tttgaccaat tccgcaagag
     7261 gatcttgcaa acgacgggcg atagaaatgg cagagcgttt ttcaacggtc aagtctggaa
     7321 actcctgacg agcaagttcg ctggcagaat agacagaagc accactttca ttaacgataa
     7381 catagctgac ttcagggaaa tctttcagaa cttccgctac aaaagcttca ctttcacgac
     7441 tggccgttcc atttccaatg gcaataatct ctacaccgta ttgaccaatt aaatctgcta
     7501 aatctttctt ggcttcttcg atttgacgag ctgatgctgg tttaacagga taaataacct
     7561 gagttgtcag catttttcct gttgcatcca cgacagctaa cttggcacct gtacgaaagg
     7621 ctgggtcaaa tccaagaacc acgcgccctt tcagtggagc aaccaagagg agattgcgca
     7681 gattgtcaga aaaaagttgg atagctcctt cttcagcttt ctcagttaat tctgtccgaa
     7741 tacgacgctc gatagcaggc aagacctttt tcttaacgga ttgctgaaca acttcatcaa
     7801 tataagcatt tttcaccttg aaacgagtag caaagaaggc aagaatacgg tccgtcgcat
     7861 gttcaaaacc gatcttcaag acaccaagtt tctccccacg attgagagcc aaggtacgat
     7921 agccttgcat agttccaact gtctctgaaa aatcataata aatctgaaaa acctgctttt
     7981 catcaagact ttcatccttg gcttgagaag taagtttaga gtgtctcagc acttcctgat
     8041 aagtcataga acgcaaggtc acatcttccg ataaggcttc gaccaaaata tcaactgcac
     8101 cggtcaaggc ttccttgcca gtcgcaaatc cttcacagac gaacttttca gcttctttct
     8161 ctaagtcaac tatattctgc aaaatcaagc gagcaagagg aaagagtcca gcttcacggg
     8221 caatggttgc cttggtacga cgcttttcct tataaggaag atagagttct tcaacgtctg
     8281 ctaatttttc ggcaactaag atagcttctt ccaattcctt ggtcaactta ccttgttctt
     8341 gaatcttagc taagacagct tccttacggt cattgagatt tgtcagactt ttatccaaat
     8401 caataatagc cttaatcgcc acctcatcca gactaccagt catgtccttg cgataacgcg
     8461 cgataaaggg aatagtcgcc ccttcagctg tcaaacttag aacggtatca atttgcttta
     8521 acgtcactcc caaatcctga gagatttttt catatttttt atccataaat ctattatacc
     8581 acaagctaaa cgtttcaaat taactcgtag aacatttaaa aaatatgtag gaaatagatt
     8641 tatatgctac agcgcaataa cttgcactta aagagcattg ccaccttttt ttaaccaagc
     8701 catgatatca aaagtattta atggatcaga cataatagcc agttctggaa gatgttcctg
     8761 acctggaata acacattgac ttttcaaatt tttatatgga cgattgacta aaattaattt
     8821 attagaataa ggaagattat ccatctta
//
LOCUS       DAVLUM010000079         8703 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLUM010000079 DAVLUM010000000
VERSION     DAVLUM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8703
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.079"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(343..1539)
                     /gene="tuf"
                     /locus_tag="VYN42_001789"
     CDS             complement(343..1539)
                     /gene="tuf"
                     /locus_tag="VYN42_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1462830.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2450..3319)
                     /locus_tag="VYN42_001790"
     CDS             complement(2450..3319)
                     /locus_tag="VYN42_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1462831.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3542..4063)
                     /locus_tag="VYN42_001791"
                     /pseudo
     CDS             complement(3542..4063)
                     /locus_tag="VYN42_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4021..5127)
                     /locus_tag="VYN42_001792"
     CDS             complement(4021..5127)
                     /locus_tag="VYN42_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1462832.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSEGRTVTLVYRESEAPTTVTVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5238..5492)
                     /locus_tag="VYN42_001793"
     CDS             complement(5238..5492)
                     /locus_tag="VYN42_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462833.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5831..6277)
                     /locus_tag="VYN42_001794"
     CDS             complement(5831..6277)
                     /locus_tag="VYN42_001794"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1462834.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6350..6675)
                     /locus_tag="VYN42_001795"
                     /pseudo
     CDS             complement(6350..6675)
                     /locus_tag="VYN42_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            6909..8627
                     /locus_tag="VYN42_001796"
     CDS             6909..8627
                     /locus_tag="VYN42_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1462835.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
BASE COUNT         2488 a         1790 c         1637 g         2788 t
ORIGIN      
        1 tactcttcga aaatctcttc aaaccgcgtc agcttcgcct tgtcgtatag atgttactga
       61 cttcgtcagt tctatctaca acctaaaaac agtgttttga gcagtctgta gctaactttc
      121 tatagtaaaa tgaaataaga acaagacaaa tcgatcagga cagtcaaatc gatttctaac
      181 aatgttttag aagtagatgt gtactattct agtttcaata tattatagtt tgctctttga
      241 ttttcattga gtattagttc aatatctaaa aaaagaacct tgccaagcaa gattctttta
      301 gtgtctgact taaataattg ttcttctggg aactaaatcg aattaagctt cgatttctgt
      361 aaccatacct gaaccaacag tacgtccacc ctcacggata gagaatgtag taccttgttc
      421 tacggcgatt gggtgaatca actcaacgtc gattgtcacg ttatcaccag gcattaccat
      481 ttcagtacct gctggaagtt cgattgaacc tgtaacgtca gtagtacgga agtagaattg
      541 tggacggtag ttgttgaaga atggagtgtg acgtccacct tcttctttag taaggatgta
      601 gacttcacct ttgaatttag tgtgtgggtt gattgaacct ggtttagcga taacttgtcc
      661 acgttcgatt tcatcacgtt gaacaccacg aagaaggaca cctacgttat ctccagcaag
      721 accttcgtca agttgtttac ggaacatttc aacaccagta acaactgctt tttgagtttc
      781 ttctttgata ccaacgattt cgatttcgtc gttgacttta acgataccac ggtcgatacg
      841 tcctgaagca actgtaccac gtccagtgat tgagaatacg tcctcgactg gaagaagcaa
      901 tggtttgtca gtgtcacgtt ctggttctgg gatatactca tcaactgtgt tcatcaattc
      961 cataacgatg tcttcgtatt tagagtcacc ttcaagagct ttaagtgctg aaccttggat
     1021 aactggaaga tcgtcacctg ggaagtcgta ttctgacaat aggtcacgga tttccatttc
     1081 aaccaattca agcaattctt cgtcgtcaac caagtcaact ttgttcatga agacgataag
     1141 gtgtttaaca ccaacctgac gtgaaagaag gatgtgctca cgagtttgtg gcattggtcc
     1201 gtcagttgaa gctactacaa ggatagctcc gtccatttga gcagcaccag tgatcatgtt
     1261 tttaacgtag tccgcgtgtc ctggagcgtc gatgtgagcg tagtgacgtt tttcagtttc
     1321 gtactcaacg tgcgcagtgt tgatagtgat accgcgttcg cgttcttctg gagcagcatc
     1381 gatagacgca tagtctttag gttggttaac tgatgaaggc aagcgacgtg ccaaaacagt
     1441 tgtgatagct gcagttaggg tagttttacc gtggtcaacg tgtccgatag taccaatgtt
     1501 aacgtgtggt ttactacgat cgtatttttc ttttgccatt tgagtaaaag cctccaataa
     1561 aatatatttt atagatagac agtaggcaat acagtctaac tttccttact attttatcaa
     1621 atttcagcta aattgcaagt gttttacaac gtttttgtga attattcttg gtaaaaattt
     1681 aactaattaa tagaaagtac taaatagact tatccttcaa ggagttttca gcattatcca
     1741 tccactcact tgctgaaaat gtaaacagtc tctggtttat atagtaaaat gaaacaagaa
     1801 tagagcaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagatgtg
     1861 tactattcta gtttcaatct actatacaac ctcaaaactg tgttttgaac aacctgcggc
     1921 tagcttctta gtttgccctt tgattttcat tgagtataaa attgcagata aaacgataac
     1981 aatcatagga ctcagcagag tcaatgtagg tcgaagaata gcccccctaa tcgcttattt
     2041 tatagcaaaa tgaaatagaa actgaacatt ttgttgagga aggtaaatca attcctcaca
     2101 atgtttgaga aagaagggag gactattcca acttcaaccc actataaagc agacttacaa
     2161 gatagggaac ccatctccga taatatatag tagaatgaaa actgcacaat ttgattggag
     2221 aattcaaacc aatttctaac aatgttttag aaacaagggt ctattatttc aactgcaacc
     2281 tactatagcc cattgaagct ggaatagccc actgagactt ctaaaccact gctggagagg
     2341 agtttgttta gagtttcttt catttcccta aaaaatcaaa aagagagaac cagtctgatc
     2401 ctctcttact tatagatggt gctcactcaa atgttaaagg agctatttct tagagataaa
     2461 ggaatttgaa tacagctact gccgcaattg ctgctgcgat aggtgctact actggtaccc
     2521 aagaatacca ccattttgaa tcgcctttat gctcaccaag aactgatttt ggaaggaaag
     2581 catgaaggag acgtggtccc aagtcacggg ctgggttcaa ggcaggtcct gtaggtcctc
     2641 caagtgatgt taccaaagcc ataacgagga atccaagtgc caagtgagcc acagaaagtc
     2701 ctgaagcagt gtgtggagcc acctgtgctt taatagccaa gtcagaaaaa tcaactgttt
     2761 gtcctgcttc tattgccttt tgtttcatga attgaagcac ttcagcacca aagaagtttt
     2821 tagtcaaacc aagagctgca aagaacaaaa caaatgaacc aacaaactca ttaatcaaac
     2881 cattgacagt tgctgcatag cgactttctt ttgtaccatg gtcaatactt gaaatagttg
     2941 agaaagttcc caagatgtta tttggttttt cagttttcaa gtagaatgga cggtatgttg
     3001 ccacaactaa ggcttggcca aagatagccc ccaagacttg cgcgataatg taaggtacca
     3061 cttgtgccca agggaaaaga ccgctaactg caagccctag agtgaaagca gggttgatgt
     3121 gattcccaga tacgttacca aacatcaagg ctgggatcat aacccccata ccataaccaa
     3181 cagcgatgac gatccagcca ctttggtgac ctttcgtacc tttaagttca acgttggcaa
     3241 ctgcaccatt cccaagaatg atcaaaatgg cagttcccaa aaattcagtg gcatacttca
     3301 gtgcccatgt gaaatccatt tgctagattc tccttaaaat tttttagata ttccttattt
     3361 tatcaatttt taccctattt agcaactgat ttctggaaat atttttaaaa aaataggatt
     3421 catagtttcc cagttcaacg tacttgtaag cgtttttatt cttcacgaaa gacctcattc
     3481 tcaaaaccag gaaaaagccc acatctgtga tcttttcctt gttcctagat tctaaaatct
     3541 attatttttc atcttctttt ttcttgaaga atcctaatcc tagaccagct aacaaggtca
     3601 tgataccagc actagccaag gtagcattag cttctgtacc tgtgtttggc aattcctctc
     3661 tcttacctgt ctcataagtc ggaacttctg ggtctggatt cactggagtt tcagtttttg
     3721 gagtacctgg ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta
     3781 tttctttatc actagagtct gacgtaactt cttgtgatta aactgttgga atatctggag
     3841 ctttgtactt gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac
     3901 cgtaggttac aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt
     3961 gaacaacatc ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg
     4021 ttatagtctt cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct
     4081 cacggtagta atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac
     4141 caaggtgtat gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt
     4201 cccttcaata gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat
     4261 aacagactct gccaacttct cttggctacc ttctttatag taattggctg ttactgtaac
     4321 agtggttggc gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat
     4381 attcccagtt aaacttgcag aatttgtatc tacttcttta aaagtataat attttccgtc
     4441 agtagtagtc atgctactga gttttttatc tgtgacattg tagctggtac caatcagttg
     4501 ttttttattg gtaatgtagg ttccgtcact ttctttttct ccaattccag tatcattttt
     4561 caatgatagc aaacgccctt gttcatcaac atagcgaact ttcacatttt ctgagattag
     4621 ttctgccaat tctgaggttt ttttcttttt cttgatttct tcggttattt tccctttctc
     4681 ttcttcggga atatttagtt ttggaatgat tttttcaaca acggttcgtg atggttccac
     4741 agtatcttgg atgactgaaa agtcagctag aattgggaga ttatactgaa cacggtgact
     4801 ttgagtgttt actcctactc tttcattatt ctctgaaaat acttgtacgg tataagaaac
     4861 aacatctttt cctaatagaa catccccagt agagaaatag ccgccttttc ctagtttgct
     4921 atctccagag cccacttctt tcctaatctt atcagatagt tttttaccag tcagtacatt
     4981 cgttcgcaca atccctttgt ctacccctac aaagtgggag aactttttaa actcttcaga
     5041 accagatcta gcccaaccat tattaagggc atttgctttt gtatttgtat tctctctcaa
     5101 aagtttggcg attagaatta tattcatcgg cacttagagt tgctgctata tctgactctt
     5161 gaataccaac ttccttacta ccatttctag cggcagtata tgtgtattta tctgtttcta
     5221 cttctagctg attatcctta acatgatagg taattttctc ctggtataag agtcttcagt
     5281 agtttatatg ctctgtcatc atctttagct ttagaagcag ctgagtttag ccaagttggg
     5341 gtattaggag tatctttatc agcctgtttc aagacattat tcaagtcatt tgctagccta
     5401 ttggttgtcc tcactgtgaa agttttcttc cagtctgaac cacttttatt agacttagat
     5461 atgctcatga aatcctggtc aacattcaac acaatatcgc cttgtttttt agcatcttcc
     5521 gttgcttctg cttcaaattg atcatggagt ttttgttgct ctggtgtata gttttttatt
     5581 tacacgattt aatgtactat tttttatttt agtattaaga actccattaa tacgattttt
     5641 aaactctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat tcaaaccttt
     5701 tttatacaag tcttcattct gaacgatttc ggctacacgg tgaatggttt gattgtatac
     5761 cgtcttctct taaccagcag tatccttagt tttaatgact actcgatagg ttcctttaga
     5821 accgttatag tcatctagtt ttaaaaaagc attccaaaca ttcaaaaata gttggaactt
     5881 cccttaataa atccgtcact ttctttttca agatagccca agcttgctca ataggattca
     5941 aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg cagagttcat
     6001 ccaaaatgtt cttgggatga aaaccagcat tgcccatgac aataacatga ggtgtcttca
     6061 aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc atgcttttct
     6121 tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt gaagttcgct
     6181 caaaacgacg tccgctaatc ttttcataga ctttctcccc tctaggagcc cctgcataag
     6241 gacgatagag atagcggtcg attcctgttt catcaatata aacaggtgct aggtgcttta
     6301 aactattaaa attcttaaga aataaggcta cttttctggg tcttgttcct taaagctcgt
     6361 catctttttt taaagtgacc ttaatctgct ttaaagctgc ccatactgaa ggaacagcac
     6421 aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg atgagcctct acaaaggctt
     6481 tcaattcctc taaaggaatc tttcggtttt tgacgactcg ctttttcctc tctatgtgtt
     6541 cttgttcacg tctttctttt cccacgtgaa gagagttctg acgccaacac caaaaaactt
     6601 ggctgcctcg acatggctgt gcccctcttt gatgtaatct aatgctcgct gtttaaaatc
     6661 agtactatat gccatagctt tattataata tgcttgttta aaactaagta actatatcaa
     6721 tgttttgtta tgagaagact tacttttttt actgaaattg aatttttcct agcctcaaca
     6781 tcatataacc ccaaaattca atctgacctg gtttgcagag attttcgaag cagataaggt
     6841 tttactaaaa ctaaaaaaaa tgatataatc aaactgatta aatgttttaa aaataaagga
     6901 gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg gagcttcctg
     6961 actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat gccttctata
     7021 caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt acaaaccgta
     7081 tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt gagtcaaaag
     7141 gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac ttctcacctg
     7201 agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct tacgtatttg
     7261 aaagccttcg tccaactcca gaactatcat ttgcagttcg tcatctcaac tgtttcgcag
     7321 gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag gtttacggtg
     7381 aagacggtgg acaaatgcct ccacacgatg cggacgcttt gactacttat atccgtgcaa
     7441 tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct tctggcttga
     7501 ttgaagttat cggcgaagct gttgacatag aataccttaa agaggttaag gacataaaca
     7561 tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac acaccacttc
     7621 atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt gactctgttc
     7681 aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca tctccaaacc
     7741 cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt ggtgcagatg
     7801 ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt caaaaagatg
     7861 gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa tacatcttgg
     7921 aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa tctatcgttt
     7981 caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc aacgtcttga
     8041 caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac aaccacactt
     8101 acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta cgtgataaag
     8161 atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt tctcgtggtt
     8221 tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac gcagaaaaaa
     8281 caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg attatggcta
     8341 aattccgcaa caatgctcca acagaatgga acgcaacagc tatcactgtc gtagaagact
     8401 tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca actcctccaa
     8461 gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc ccttcaggta
     8521 cagaaccaaa aatcaagttc tacattgcag ttgtagggga aaccaacgaa gaatcacaag
     8581 ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga cctataaaag
     8641 atggcttttt gtcaactgta gtgggttgaa aaaaagctaa gctcgagaaa ggacaaattt
     8701 cgt
//
LOCUS       DAVLUM010000080         8435 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLUM010000080 DAVLUM010000000
VERSION     DAVLUM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8435
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.080"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..336
                     /locus_tag="VYN42_001797"
     CDS             <1..336
                     /locus_tag="VYN42_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1462836.1"
                     /translation="GEVLSTPLIGEPLIGHTDTFLSIGNFKTKFEADACIKFIKTKFA
                     RVLLGVLKVTQHNSRKTWYYVPLQDFTVNSDIDWTQSVTDIDRQLDQKYDLSPEEIAF
                     IENHVREMD"
     gene            501..3755
                     /locus_tag="VYN42_001798"
     CDS             501..3755
                     /locus_tag="VYN42_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1462837.1"
                     /translation="MPVEIKTTKEIHPKIYAYTTPTVTSNEGWIKIGYTERDVTQRIK
                     EQTHTAHIATDVLWTGDAAYTEEPDKGKTFKDHDFHHFLSFHDVERRPKTEWFYFNGT
                     PEKSKNLFDKFVQHDLSGYQPGKGQDYTLRQEQEEAVAKTLAYFQEHAGGKFLWNAKP
                     RFGKTLSTYDLARRMEAVNVLIVTNRPAIANSWYDDFETFIAGQTTYKFVSESDSLKS
                     RPILSRQEFLGILADDVRQLAFISLQDLKGSVYLGGEHDKLKWVTDLHWDLLVIDEAH
                     EGVDTFKTDQAFNKIRQNFTLHLSGTSFKALAKGDFTEEQIYNWSYADEQAAKYSWSL
                     EQEEENPYESLPQLNLFTYQMSQMIGEKLEKGAQIDGENIDYVFDLSEFFATDDKGKF
                     IHEHDVRNWLDTLSSNEKYPFSTKELRNELKHTFWLLERVASAKALKALLEEHPIYEN
                     YEIVLAAGDGRMSEEDDKVKLKSLDLVRKAIAENDKTITLSVGQLTTGVTIPEWTGVL
                     MLSNLKSPALYMQAAFRAQNPYSWSDNKGNHFRKERAYVFDFAPERTLILFDEFANNL
                     SLVTAAGRGTSATREENIRELLNFFPIIAEDRAGKMVEIDAKAVLTTPRQIKAREVLK
                     RGFMSNLLFDNISGIFQASQTVLDILNELPVEKEGKVQDSSDLLDFSDVTVDDEGNAV
                     VDHEIVVNQQMRLFGEKVYGLGESVAELVTKDEERTQKQLVNDLSKTVSSVIVEELKA
                     DYSLKTRETEQIKKQITATLENEIRKNDIERKISEAHIKQELQQQLKEANDKAQKDKI
                     QEDLEKRLEENKLIHKEKLEQTLKKEVEKMPEKFIEQVEIKRVEQLKQSAQDEIRDHL
                     RGFARTIPSFIMAYGDQTLTLDNFDAFVPEHVFYEVTGITIDQFRYLRDGGQDFAGHL
                     FDKATFDEAIQEFLRKKKELADYFKDQKEDIFDYIPPQKTNQIFTPKRVVKRMVDDLE
                     KENPGIFDDPSKTFIDLYMKSGLYIAELVKRLYNSNGLKEAFPNPEERLKHILEKQVY
                     GFAPSEIIYNISTNFIFGNLSKDISRKNFVLADTIPAAKEGSIQKLVDSYFENN"
     gene            complement(4053..5039)
                     /locus_tag="VYN42_001799"
     CDS             complement(4053..5039)
                     /locus_tag="VYN42_001799"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1462838.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            5233..7701
                     /gene="gyrA"
                     /locus_tag="VYN42_001800"
     CDS             5233..7701
                     /gene="gyrA"
                     /locus_tag="VYN42_001800"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1462839.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDVVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            7701..>8435
                     /gene="srtA"
                     /locus_tag="VYN42_001801"
     CDS             7701..>8435
                     /gene="srtA"
                     /locus_tag="VYN42_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1462840.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQ"
BASE COUNT         2709 a         1460 c         1816 g         2450 t
ORIGIN      
        1 ggtgaagtct tatcaacacc cctaatcggg gaacccctaa tcgggcatac agatactttt
       61 ttatctattg gtaattttaa aacaaaattt gaagccgatg cttgtattaa atttattaaa
      121 actaaattcg ctagagtatt attaggtgtt ttgaaagtta ctcagcataa ttcacgcaaa
      181 acttggtatt acgtccccct ccaagacttt acggtcaatt cggacattga ttggacacaa
      241 tcagtgactg atattgaccg ccagcttgat caaaaatatg acctttcccc tgaagaaatt
      301 gcctttattg agaatcatgt aagggagatg gattagaaaa gtatttttat ttgacaaata
      361 gtgctcaatg atctaaaatg actatatagg attaggtcag gaagcatacg atgccctgac
      421 cctttttgta cttatgagat gagaaagtca tttgttagat aaattgactt cgttagcaaa
      481 cgttcaaaaa aggaaaactt atgccagtag aaattaaaac cactaaagaa attcatccta
      541 aaatctatgc ctacaccaca ccgacagtaa ccagtaatga aggctggatt aagattgggt
      601 atacagaacg tgatgtcaca caacgtatca aggagcaaac gcatacagct catatagcta
      661 cagatgtctt atggactggt gatgcagctt atacagaaga gcctgataag gggaaaactt
      721 tcaaggacca tgatttccac catttccttt ctttccatga tgtagaacgt cgtcccaaga
      781 cggaatggtt ctattttaat ggaactcctg aaaaatcaaa aaatcttttt gataagtttg
      841 ttcagcatga tttgtctggt tatcagcctg gaaaaggaca ggactatact ctgcgacaag
      901 agcaagaaga agcagttgct aagacattag cttatttcca agaacatgct ggaggcaagt
      961 ttctctggaa tgccaagcca cgctttggta aaaccttgtc tacctatgac ctagctcgac
     1021 ggatggaagc tgtcaatgtc ctaattgtaa caaaccgccc tgccattgct aactcatggt
     1081 atgatgattt tgaaacattc atagcaggtc aaacgactta caagtttgtt tctgaatcag
     1141 atagccttaa gagtcgtcca atcttgtcac gacaagaatt tcttggtatt ttagctgacg
     1201 atgtaagaca acttgctttt atcagtctcc aagacttgaa aggatctgtt tatttaggtg
     1261 gagagcacga taaactcaaa tgggtaactg atctgcattg ggacttgttg gttattgacg
     1321 aggctcatga aggagttgat accttcaaga ctgaccaagc ctttaataag attcgacaaa
     1381 attttactct gcatttgtca ggtacatcat ttaaagcatt ggctaaagga gattttacag
     1441 aggaacaaat ctacaactgg tcttatgctg atgagcaggc tgctaagtat tcgtggtctc
     1501 ttgagcaaga agaggaaaat ccttatgaaa gcttgcctca gttgaatctc tttacctatc
     1561 aaatgtctca gatgattggc gaaaagttag aaaaaggcgc tcagatcgat ggtgaaaata
     1621 ttgactatgt ttttgactta agtgaatttt tcgctacaga tgataaaggg aaatttattc
     1681 atgagcatga tgtcagaaat tggttagata ctctatcaag caatgaaaaa tatccatttt
     1741 caaccaaaga actccgtaat gaactcaagc atactttttg gcttttagaa cgtgtcgctt
     1801 cggccaaagc attaaaagcc ctactagaag aacacccaat ctatgaaaac tatgagatcg
     1861 ttctagctgc tggtgacgga cgtatgtccg aagaagacga taaagtcaaa ctcaaatcct
     1921 tggacttggt tagaaaagcg atagcagaga atgacaaaac cattacccta tccgttggtc
     1981 agctgacgac aggtgtcact atccctgaat ggacaggtgt attgatgtta tcaaatttga
     2041 aatcaccagc tctttatatg caggccgcct tccgtgctca aaatccttac tcatggagcg
     2101 ataacaaagg aaatcacttt cgcaaagaaa gagcctatgt atttgacttt gcgccggaaa
     2161 gaaccttgat tctctttgat gagtttgcca acaacttatc gcttgtaact gcagctggta
     2221 gaggaacttc agctacacgc gaagaaaata ttagagaatt attaaacttc tttccaatta
     2281 ttgccgaaga ccgtgctggt aagatggttg aaattgatgc aaaggcagtt ctaaccactc
     2341 ctcgccagat aaaagctaga gaagttctta aacgaggttt tatgtccaat ctcttatttg
     2401 ataatattag tggtattttc caagcaagtc aaacagtttt agatatttta aatgagctgc
     2461 cagttgaaaa ggaagggaag gtacaagata gttctgattt attagatttt tcagatgtta
     2521 cagtcgatga tgagggaaat gcagtagtag accatgaaat tgtagttaat cagcaaatgc
     2581 gactttttgg tgaaaaagtt tatggacttg gtgaatctgt tgctgagtta gtcacaaaag
     2641 atgaggaacg aactcaaaaa cagctggtca atgacttgag taagaccgtt tcttcagtga
     2701 ttgtagagga attgaaagca gattattctc taaaaacaag ggaaactgag caaattaaga
     2761 aacaaattac agcaacactt gagaatgaaa ttcgaaaaaa tgatatcgaa agaaaaattt
     2821 ctgaagctca tatcaagcaa gagttgcaac agcagctcaa agaagcaaat gataaagcgc
     2881 aaaaagataa gattcaagaa gatttggaaa aacgtttaga agaaaataaa ctcattcata
     2941 aagaaaaact agaacaaaca ctcaaaaaag aagtggaaaa aatgcctgag aaatttatcg
     3001 aacaggttga gataaaacgt gtggaacagt tgaaacaatc agctcaagat gaaattcgtg
     3061 accatttacg agggtttgca agaacaattc caagttttat tatggcttac ggtgatcaaa
     3121 ctctaacact tgataatttt gatgcctttg ttcctgaaca tgttttttat gaagtaacag
     3181 ggattacgat tgatcagttt agatatttgc gagatggtgg gcaggatttt gcagggcatc
     3241 tctttgataa agcaacattt gacgaagcta ttcaagaatt tcttcgcaag aaaaaggagt
     3301 tggcggatta ttttaaagat caaaaagaag acatttttga ctatattcca ccgcagaaga
     3361 ccaaccaaat tttcactcct aaacgagtgg tgaaaaggat ggtagatgat ttggaaaagg
     3421 aaaatccagg gatttttgat gatccatcta agacttttat tgatttatat atgaagtcag
     3481 gcctctatat tgcagaactt gtgaagcggt tatataatag caatggcttg aaagaggcct
     3541 ttccaaatcc tgaagaacgc ttaaaacata ttttggaaaa gcaagtttat ggatttgctc
     3601 cgtctgagat tatctataac atttccacta attttatatt tggcaatctt tctaaagata
     3661 tcagtaggaa gaattttgtt ttagcagata ccattccagc ggctaaagaa gggagcattc
     3721 aaaagttggt tgattcctat tttgaaaata attaaaaaga aggccgagtc aaaattcttt
     3781 gaaatcagaa aaaacgcata atattgagtg cttttgtact gccccccaaa agttagacag
     3841 aaaaaatcta acttttgggg ggcagttcag acaatccttg gtattatgcg ttttattgtg
     3901 ggaagatgta taatggattg aaataagata tgaacaaatc gattaggaat ttaaagcatt
     3961 ttataacaac gttttagagt aacggggtac tatttcatat aatacaggaa aaaacaactc
     4021 cctgatgatt caaggagttg tctatagtta aattagtttt tagaagcttc ttggaattct
     4081 ggatttttcc atgcttcgtc aataatagct tgcaattctt tagcagatgc ttgcattttt
     4141 tgagtttctg catcgttcaa tggaatgttt actggacgaa cgataccatg tgcaccaaca
     4201 acagctggtt gaccgataaa gacattctca actccgtatt gaccttcttg gaatactgaa
     4261 agtggaagta ctgcgttttc atcgtcaagg attgctttag tgatacgagc aagggctact
     4321 gcgataccgt agtatgttgc accttttttg ttgatgattg tgtaggctgc atcacgaaca
     4381 ccttcgaaca attcaatcaa ttcagcttct tgaacatttt gagtgtcttt aaggaattct
     4441 tcaaggttta caccagcgat gttagcgtgt gaccaaacag cgaactcaga gtcaccgtgt
     4501 tcacccatga tgtaggcgtg cactgaacga gcatccacat ccaatttttc agcaagtgct
     4561 tgacggaaac gagctgagtc aagtgaagta cctgaaccga taacgcgttc tttagggaaa
     4621 ccagagaatt tccaagttga gtaagtcaaa acgtcaactg ggttagcagc aacaaggaag
     4681 atacctttga aaccagattc aacaacttga gttacgattg atttgttgat agcaaggttt
     4741 ttacctacaa ggtcaagacg agtttcacct ggtttttgag gtgcacctgc agtgatcaca
     4801 acaaggtcag cgtctgcaca gtcagagtat tgagctgcat agattttttt aggtgaagtg
     4861 aaggcaaggg cgtgactaag gtcaagcgca tcaccaacag ctttttcatg caattgtgga
     4921 atttcgataa ttccaagctc ttgtgcaatt ccttggttaa caagtgcaaa agcgtaagat
     4981 gaacctacag caccatcacc gacaaggata acttttttgt gttgtttagt tgaagtcatt
     5041 gttttaaaca tctccttaat tttattaggg gattttccct agacaacttc attctatcac
     5101 ttttaaaaaa ctttgtcacg aatatgcctt atagttctcg atgtaaacgt tttagtggtt
     5161 tagaggctga aatagatggg aatttatggt ataatgttgt tacttactaa ttgtgaaatg
     5221 aggcatttat taatgcagga taaaaattta gtgaatgtca atctgacaaa ggagatgaag
     5281 gcaagtttta tcgactacgc catgagtgtt atcgtagcgc gagctcttcc tgatgttcga
     5341 gatggcttaa aacctgttca ccgtcgcatt ctctacggaa tgaatgaatt gggtgtgacc
     5401 ccagacaaac cccataaaaa atctgctcgt attacagggg atgtcatggg taaatatcac
     5461 ccacacgggg attcctctat ttatgaagcc atggtccgta tggctcaatg gtggagctac
     5521 cgttacatgc ttgtagatgg tcatgggaat tttggttcta tggatggaga tagtgctgcc
     5581 gctcaacgtt ataccgaggc acgtatgagc aagattgctc tggaaatgct tcgtgatatc
     5641 aacaaaaata cagttgattt cgttgataac tatgatgcca atgaacggga acccttggtc
     5701 ttgccagcgc gttttccaaa ccttttggtt aatggagcaa ctggtatcgc ggttgggatg
     5761 gcaaccaata ttccacctca taatctgggt gaaaccattg atgtagtgaa gttggtcatg
     5821 gataatcctg aagtgactac caaggacttg atggaagtct tgcctggacc agattttcca
     5881 actggtgctc ttgtcatggg gaaatcaggt atccataagg cttatgaaac aggtaaaggt
     5941 tcgattgtcc tacgttctcg tacagagatt gaaacgacta agactggtcg tgagcgcatc
     6001 gttgtaacag aatttcctta catggtcaat aaaaccaagg tgcatgagca tattgttcgc
     6061 ttggttcagg aaaaacgcat tgagggtatc acagcagtac gtgatgagtc aaaccgtgaa
     6121 ggtgttcgat ttgttattga agtcaagcgc gacgcctcag ccaatgttat tctcaataac
     6181 ctcttcaaaa tgacccaaat gcaaaccaat tttggtttca atatgctcgc tatccaaaat
     6241 ggtataccga aaattttgtc tcttcgtcag attttggatg cttatatcga gcaccaaaaa
     6301 gaagtggttg ttcgtcgtac acgttttgat aaggaaaaag cggaagcgcg cgctcatatc
     6361 ttagaaggtc tcttgattgc gctagaccat atcgacgaag tgattcgtat catccgtgct
     6421 agtgaaacgg atgcggaagc tcaagctgag ttgatgagca agtttaagct ttctgaacgt
     6481 caaagtcaag ctatccttga tatgcgtctt cgtcgtttga caggtttgga acgcgataag
     6541 attcaatctg agtatgatga cctcttggct ctgattgcgg atttagcaga tattcttgct
     6601 aagcctgaac gtgtttctca aattatcaaa gacgaattgg atgaagttaa acgtaaattt
     6661 tctgataaac gccgtacaga gttgatggtt ggacagatct tgagtctcga ggatgaggac
     6721 ttgattgaag aatcggatgt cttgattacc ctttctaaca gaggctacat taagcgtttg
     6781 gatcaggacg agttcactgc tcaaaaacgt gggggtcgtg gtgtccaagg aacgggagtg
     6841 aaagatgatg actttgttcg tgagttagtg tcaactagca cccatgatca tctgctcttc
     6901 ttcacaaaca agggacgtgt ctatcgtctt aaaggttatg aaattcctga gtatggtcgg
     6961 actgccaaag ggctaccagt agtcaatctc ttgaaattgg atgaagacga aagtattcag
     7021 acggttatca atgttgagtc tgatcgcagt gatgatgctt atctcttctt tacaacccgt
     7081 cacggtattg tgaagagaac cagtgttaag gagtttgcca atattcgtca aaatggtctc
     7141 aaagcgctga atttaaagga tgaagatgag ttaatcaatg tcttgttggc agaaggagat
     7201 atggatatta tcattggtac caagtttggt tatgcagttc gctttaatca atcagccgtt
     7261 cgtggtatga gtcgtatcgc cactggtgtg aaaggtgtta accttcgtga aggagacaca
     7321 gttgttggtg ccagcttgat tactgatcaa gatgaggttc ttattatcac agaaaaagga
     7381 tatggtaagc gtacagtcgc tactgaatac ccaacaaaag gtcgtggtgg taagggaatg
     7441 cagacagcta aaattaccga aaaaaatggc ttgctggccg gtcttatgac tgttcaaggg
     7501 gatgaggatt tgatgattat cactgataca ggtgtcatga ttcgaaccaa tcttgccaat
     7561 atttcacaaa caggacgtgc aactatggga gttaaagtaa tgcgcctgga tcaagatgct
     7621 cagatagtga ctttcacaac ggttgcggtg gcagaaaaag aggaagttgg gacagaaaat
     7681 gaaacagaag gtgaagcata atgtctcaaa aaaataataa aaagaaaaac aagcgaaaaa
     7741 atctgctgac aaatatccta gcaggatttc tgatattact gtcactggct ttgattttta
     7801 atactcaaat tcgaaatatt ttcatagtct ggaataccaa taagtatcaa gttagccagg
     7861 tatcaaaaga gaaattagaa gaaaatcagg atacagaagg caattttgac tttgattctg
     7921 tcaaagctat ctcttcggaa gctgttctaa cttctcaatg ggatgctcaa aaattaccag
     7981 ttattggggg aattgcaatt cctgaattgg aaatgaattt gccgattttt aaaggacttg
     8041 ataatgttaa tctcttctac ggagctggta caatgaaacg cgagcaagta atgggagaag
     8101 gaaattatag tctagctagt caccatatct ttggtgttga taatgctaat aaaatgttat
     8161 tttctccttt agataatgct aaaaatggca tgaagattta tctaaccgat aaaaataaag
     8221 tttatactta tgaaatacgt gaagtcaaac gtgtgacacc ggatcgtgtt gatgaagttg
     8281 atgatagaga tggggtcaat gaaatcacat tagtaacctg tgaagacctt gctgctacag
     8341 aacgtattat tgtcaaaggt gatttgaaag aaacaaaaga ttattcacaa acatctgatg
     8401 aaatcctaac agctttcaat caaccatata aacaa
//
LOCUS       DAVLUM010000081         7654 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLUM010000081 DAVLUM010000000
VERSION     DAVLUM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.081"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            1..655
                     /locus_tag="VYN42_001802"
                     /pseudo
     CDS             1..655
                     /locus_tag="VYN42_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            716..1473
                     /locus_tag="VYN42_001803"
                     /pseudo
     CDS             716..1473
                     /locus_tag="VYN42_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            1650..2657
                     /gene="gap"
                     /locus_tag="VYN42_001804"
     CDS             1650..2657
                     /gene="gap"
                     /locus_tag="VYN42_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1462841.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2724..3560)
                     /locus_tag="VYN42_001805"
     CDS             complement(2724..3560)
                     /locus_tag="VYN42_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1462842.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3686..5881
                     /locus_tag="VYN42_001806"
     CDS             3686..5881
                     /locus_tag="VYN42_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1462843.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEASWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTSGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5934..6086
                     /gene="rpmG"
                     /locus_tag="VYN42_001807"
     CDS             5934..6086
                     /gene="rpmG"
                     /locus_tag="VYN42_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1462844.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6096..6272
                     /gene="secE"
                     /locus_tag="VYN42_001808"
     CDS             6096..6272
                     /gene="secE"
                     /locus_tag="VYN42_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1462845.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6327..6863
                     /gene="nusG"
                     /locus_tag="VYN42_001809"
     CDS             6327..6863
                     /gene="nusG"
                     /locus_tag="VYN42_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1462846.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6985..7464
                     /locus_tag="VYN42_001810"
     CDS             6985..7464
                     /locus_tag="VYN42_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1462847.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            7557..7628
                     /locus_tag="VYN42_001811"
     tRNA            7557..7628
                     /locus_tag="VYN42_001811"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7590..7592,aa:Glu,seq:ttc)
BASE COUNT         2413 a         1325 c         1662 g         2254 t
ORIGIN      
        1 tactgacaat ccagatgctt atttgactga aatagcttct gaatttggct gtcatccaac
       61 taccatccac tatgcgctca aagctatggg ctacactcga aaaaaaagaa ccacacctac
      121 tatgaacaag acccagaaaa agtagcctta tttcttaaga attttaatag tttaaagcac
      181 ctagcacctg tttagattga cgaaacagga ttcgatactt atttttatcg agaatatggt
      241 cgctcattaa aaggtcagtt aagaagaggc aaagtatctg gaagaagata tcagagaatt
      301 tctttggttg caggtctaac aaatggtgaa ttaatcgttc caatgactta cgaagagacg
      361 atgacgagcg acttttttga agtatggttt cagaagtttt tcttaccaac attaaacaca
      421 ccatcggtta tcaccatcgg ttattattat ggataatgca agattccata gaatggggaa
      481 gctagaactt ttatgcgaag agtttgggca taaactttta cctcttcctc cctactcgcc
      541 tgagtacaat cctattgaga aaacatgggc tcatatcaaa aagcacctca aaaaggtatt
      601 accaagttgc aatacctttt acgaggctct tttgtcttgt tcttgtttca attgactata
      661 gttcacggat acagttggga aagaagctat taattatttg gagagtcctt ttgggatgaa
      721 catgtcaaat attactatag atgggcaaga aatggatctg agtcaaacga tgccttctta
      781 tgctcaagta gtgagtcttt atgaggatac aagcatctct gttagtagta atgagacgga
      841 caaagtgttg gctggatccc tctatactga tacaaatgaa cagggattaa cgattccaag
      901 cagtttacta aaaaattgga atgaacagac aggaaaaaat ttgacagcta atgatcttat
      961 tggcaaatca gtctcagcca gcattataga aagtgctgcc gaaataagaa gtatactgtg
     1021 ctttctcaac agagagttct tgatattgtg attaccttta ttcgtgttat tcagggatta
     1081 ttgattgtgc tttcatcaca agctattgtg gtagcagcgg ttatgattgg tattattatt
     1141 tacatcaata tcatgcaacg ttccaaggaa ataggtgtca tgaaagcagt tggttatcag
     1201 aatcgtgatg tcaaaggaat ttttatttac gaggctatct ggattgtagg catcgccttg
     1261 ttgctggcat ttttggttgc acaaggggtg ggaagtttgg cgaatgcgat tgtaagtcac
     1321 ttttacccat ccatcactaa ggtttttgaa ttaaatcttt tatctgtttt aggaactcta
     1381 gttttcgctc tattacttgg ttatgtctca gcctacttcc cggcgcgtaa gattagtaaa
     1441 atggatcctg tagaaccgtt acgctatgaa tagtaaggga ttccttgatt tacagtctta
     1501 aaaagaaact aacatagaaa aacaatggcc atacttgcaa ttcaactcaa atagttgtat
     1561 aataggtttg ttgaaaggtg atttgtagtg attcaagtta ctcttttcac aataaaaatt
     1621 tcatgatttt cataaggagg aaatcactaa tggtagttaa agttggtatt aacggtttcg
     1681 gacgtatcgg tcgtcttgct ttccgtcgta tccaaaacgt agaaggtgtt gaagttacac
     1741 gcatcaacga ccttacagat ccagttatgc ttgcacactt gttgaaatac gacacaactc
     1801 aaggtcgttt cgacggtact gttgaagtta aagaaggtgg atttgaagtt aacggtaaat
     1861 tcatcaaagt ttctgctgaa cgtgatccag aacaaatcga ctgggctact gacggtgtag
     1921 aaatcgttct tgaagctact ggtttctttg ctaagaaaga agcagctgaa aaacacctta
     1981 aaggtggagc taaaaaagtt gttatcactg ctcctggtgg aaacgacgtt aaaacagttg
     2041 tattcaacac taaccacaac gttcttgacg gtactgaaac agttatctca ggtgcttcat
     2101 gtactacaaa ctgcttggct ccaatggcta aagctcttca agacaacttt ggtgttgttg
     2161 aaggattgat gactactatc cacgcttaca ctggtgacca aatgatcctt gacggaccac
     2221 accgtggtgg tgaccttcgc cgtgctcgcg ctggtgctgc aaacatcgtt cctaactcaa
     2281 ctggtgctgc aaaagctatc ggtcttgtaa ttccagaatt gaatggtaaa cttgacggat
     2341 ctgcacaacg cgttccaact ccaactggat cagttactga attggtagca gttcttgaaa
     2401 agaacgttac tgttgatgaa gtgaacgcag ctatgaaagc agcttcaaac gaatcatacg
     2461 gttacacaga agatccaatc gtatcttcag atatcgtagg tatgtcttac ggttcattgt
     2521 ttgacgcaac tcaaactaaa gttcttgacg ttgacggtaa acaattggtt aaagttgtat
     2581 catggtacga caacgaaatg tcatacactg cacaacttgt tcgtactctt gaatacttcg
     2641 caaaaattgc taaataattc ttgagttgat agaaagcaag gctttgtggt cttgcttttt
     2701 atatggaaaa atggatgaca cgatcatcca ttctttttta attctttttc aaatgtattt
     2761 gaaagggtag tgaaagttag cttctctaaa gtaagtgggt gggtaaagga aagtcggaag
     2821 gcatgaagca taagccgact tgtctttgat ttactattat agagagggtc gcccaggata
     2881 ggaagattat gatgcgaaag gtgcacacga atctgatggg ttcgccctgt ctttagcttg
     2941 caacgagcca aggaagtctt gtttgagaat tgctttaatc tgcttacata cgtttcagca
     3001 tattgcccat tttttgcatc aactattctt tttctacgat catggcgatc acgtccaatt
     3061 ttgtctctga aaacaagttc ttttctgttg atatttccat caactagagc ccaatattct
     3121 ctagaaatct cttttttctc caataagcga ttgagaatgg gcaggataaa aggatttttg
     3181 gcaaagagaa ctaagccact ggtttccatg tccagacgat gaacgacata gcaggtttgg
     3241 ccaacatagg tactgacatg gttaagaagg gcaatttcgt ttggttgatt accatgcgtt
     3301 ttcatcccct ctggtttgtt tacaataatc aagtgttgat cttgataaac ttcctgcact
     3361 aagtctgggt tgccccaagg gatcgtcttt tgggaataat cttcctcgtc aaaagtcaac
     3421 tggcaaacat ctccaggatt tacgatttcc ttccagtgga cttcttcttg atttatcaaa
     3481 atatgtttct tgattctcaa aaaatgacgg atttttctag ggatgaggag ttgttcctca
     3541 agtaattgct ttactgtcat ttgaggtaga gaggcgggta atgtaaatgt gaattgcata
     3601 cagatattgt aacaaaaaaa gccctatttg gataggaaat agctaaattc ttgtcttcct
     3661 atgatgaaga tgataaaata aacgcatgaa attagataaa ttatttgaga aatttctttc
     3721 tctttttaaa aaagaaacaa gtgaactaga ggactctgat tctactatct tacgtcgctc
     3781 tcgtagtgat cgaaaaaaat tagcccaagt aggtccgatt cgaaaattct ggcgtcgtta
     3841 tcatctaaca aagattatcc ttatactagg tttgagtgca ggcttgctag ttggaatcta
     3901 tttgtttgct gtagccaagt cgaccaatgt caatgatttg caaaatgcct tgaaaactcg
     3961 gactcttatt tttgaccgtg aagaaaaaga ggctggtgcc ttgtctggtc aaaagggaac
     4021 ctatgttgag ctgactgaca tcagtaaaaa cttgcagaat gctgttattg cgacagaaga
     4081 ccgttctttc tataaaaatg acgggattaa ctatggccgt tttttcttgg ctattgtcac
     4141 tgctggacgt tcaggtggtg gctctaccat tacccaacag ctggctaaaa acgcctattt
     4201 atcgcaggat caaactgttg agagaaaagc gaaagaattt ttccttgcct tagaattaag
     4261 caaaaaatat agtaaggagc aaattctaac catgtacctt aacaacgctt attttggaaa
     4321 tggtgtgtgg ggtgtagaag atgcgagtaa gaaatacttt ggagtttctg catcagaagt
     4381 gagtctggat caagctgcga ctctggcagg gatgctcaag gggccggaac tgtataatcc
     4441 cttgaattcc gtagaagatt ctactaatcg gcgcgatact gtcttgcaga atatggttgc
     4501 agcaggatat attgataaaa accaagaaac cgaagctgct gaagttgata tgacttcgca
     4561 attgcacgat aagtatgaag gaaaaatctc agattaccgt tacccctctt attttgatgc
     4621 ggtggttaat gaagctgttt ccaagtataa tctaacagag gaagagattg tcaataatgg
     4681 ctaccgcatt tacacagagc tggaccaaaa ctaccaagca aatatgcaga ttgtttatga
     4741 aaacacatcg ctatttccga gggcagagga tggaacgttt gctcaatcag gaagtgtagc
     4801 cctcgaaccg aaaacagggg gagttcgtgg agttgtcggt caagttgctg acaatgataa
     4861 aactggattc cggaatttca actatgcaac ccaatcaaag cgtagtcctg gttctacaat
     4921 taagccttta gttgtttata cgccagcagt tgaagcaagc tgggctttga ataagcagtt
     4981 ggataaccat accatgcagt atgacagcta taaggttgat aactatgcag ggatcaaaac
     5041 gagtcgagaa gttcctatgt atcaagcctt ggcagaatcg cttaatctac ctgctgttgc
     5101 cactgttaat gatttgggtg tcgacaaggc ttttgaggca ggcgaaaaat tcggactcaa
     5161 catggaaaag gtcgaccgtg ttcttggtgt cgccttggga agcggtgttg aaaccaaccc
     5221 tcttcaaatg gctcaagcat acgccgcctt tgcaaatgaa ggtttaatgc ctgaagctca
     5281 ttttattagt agaattgaaa atgctagtgg acaagttatt gcgagtcata aaaattcaca
     5341 aaaacgggtg attgataagt ctgtagctga caagatgacc agtatgatgt tggggacttt
     5401 caccaacggt accggtatta gttcatcgcc tgcagactat attatggcag ggaaaactgg
     5461 aacaactgaa gcagttttta atccggagta cacaagtgac cagtgggtaa ttggttatac
     5521 tccggatgta gtgattagcc actggcttgg ctttccgacc actgatgaaa accactatct
     5581 agctggctct acttcaaacg gtgcagctca tgtctttaga aacattgcca ataccatttt
     5641 accttatacg tcaggaagta cctttacggt tgaaaatgct tataagcaaa atggaattgc
     5701 accagccaat acaaaaagac aagtacaaac caatgataat agccagacag atgataattt
     5761 gtctgatatt cgagggcgtg cgcaaagtct agtagatgag gctagccggg ctatctcaga
     5821 tgcgaagatt aaggaaaagg ctcaaacaat atgggattcg atagtcaatc tatttcgcta
     5881 agatgcttgt caaagcctag ctttcttgtt ataattgata agatggaggc gttatggcac
     5941 taaaaaaagc aagcctagct tgtgcggttt gtggttcgag aaactattca atcaagatca
     6001 gcggaaaccc caagcctaca cgactagaag taaataaatt ttgtaagcat tgtggcaagt
     6061 acactacaca tagagaaacg agataggaga gagcgatgcg ttttattgga gatattttta
     6121 gacttcttaa agacacaacg tggccaactc gcaaggaaag ctggagagat tttcgttcta
     6181 tcatggaata cacagctttc tttgtagtaa ttatttacat ttttgaccag ttgattgttt
     6241 caggtttgat tcgatttatt aacatttttt agaagattag tggagttaat tacactagaa
     6301 atcttctatt tatgaaagga aatatcatgg atagttttga taaaggatgg tttgttttac
     6361 aaacttattc tggttatgaa aataaggtga aagaaaatct attacaacgt gcacaaacct
     6421 acaatatgtt ggataatatt ctacgcgttg aaattccaac acaaacagtg caagttgaaa
     6481 aaaatggaaa gagaaaagaa gtagaagaaa atcgctttcc aggttatgtt cttgtagaaa
     6541 tggtcatgac agatgaagct tggtttgttg ttcgaaacac accaaatgtt acaggatttg
     6601 tcggatcaca cgggaacaga tcaaaaccaa ctccattatt ggaacaagaa attcgtgaca
     6661 ttttggtatc tatgggacaa actgttcaag aatttgattt cgatgttgag attggtcaaa
     6721 ctgtacgtat tattgatggt gcttttgcag actacactgg taagattaca gaaattgata
     6781 ataacaaagt gaaaatgatt atctctatgt ttggtaatga cacagttgca gaagtaaacc
     6841 taaaccaaat cgcagaatta taaccctgag agaggctgga gcctctcttt tttgtgcagt
     6901 ttaggagcta aagggaacag aatggagaaa atggaacaaa tgtgttttct aatctgttag
     6961 actgtatcta gaaaggggaa aattatgatt aaagaattgt atgaagaagt ccaagggact
     7021 gtgtataagt gtagaaatga atattacctt catttatggg aattgtcgga ttgggaccaa
     7081 gaaggcatgc tctgcttaca tgaattgatt agtagagaag aaggactggt agacgatatt
     7141 ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc gaattttaga ctatatccgt
     7201 aagcaggaaa gtcagaagcg tagatacgat aaagaaccct atgaagaagt gggtgagatc
     7261 agtcatcgta taagtgaggg gggtctctgg ctagatgatt attatctctt tcatgaaaca
     7321 ctaagagatt atagaaacaa acaaagtaaa gagaaacaag aagaactaga acgcgtctta
     7381 agcaatgaac gatttcgagg gcgtcaaaga gtattaagag acttacgcat tgtgtttaag
     7441 gagtttacta tccgtaccca ttagtaagtc atgcaaaaaa atgaaaaaaa ttagaaaaag
     7501 tagttgacaa agtttgaaaa ggctgtataa tagtaagagt tgaaaatagc aactcaggtc
     7561 cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt cgaatcccgt
     7621 acggactatg gtatgttgcg tcaggaccac ttga
//
LOCUS       DAVLUM010000082         7613 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLUM010000082 DAVLUM010000000
VERSION     DAVLUM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.082"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            662..901
                     /locus_tag="VYN42_001812"
     CDS             662..901
                     /locus_tag="VYN42_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462848.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            886..1164
                     /locus_tag="VYN42_001813"
     CDS             886..1164
                     /locus_tag="VYN42_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462849.1"
                     /translation="MYNDVIERISLCEFIGDIFYSKITSCCIVAKDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            1451..3304
                     /gene="pspA"
                     /locus_tag="VYN42_001814"
     CDS             1451..3304
                     /gene="pspA"
                     /locus_tag="VYN42_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV1462850.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEDAPVANQSQAEK
                     DYDAAMKKSEAAKKEYEDAKKVLAEAEAAQKKYEDDQKKTEEKAEKAKAASEEIAKAT
                     EEVQKAVLDYITAIRNHNESGKKSAEEAEKKAKERETAARKKFDTIQTTIVVPEPDEL
                     AKTQKKAEEAAKNKPELTKKLEEAKVKLEEAEKKATEAKQKLDAEEVALQAKIAELEY
                     EVQRLEKELEEINESDSEDYAKEGFRAPLQSKLDAKKAKLLKLEELSGKIEELDAEIA
                     ELEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEPETPAPAPAPA
                     PAPAPAPTPEAPAPAPAPKPAPAPKPAPAPAPKPAPAPKPAPAPAPKPEKPAEKPAPA
                     PKPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWY
                     YLNANGAMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNASGAMATGWAKVNGS
                     WYYLNANGSMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDG
                     DTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            3705..4826
                     /gene="mnmA"
                     /locus_tag="VYN42_001815"
     CDS             3705..4826
                     /gene="mnmA"
                     /locus_tag="VYN42_001815"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1462851.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            4967..5422
                     /locus_tag="VYN42_001816"
     CDS             4967..5422
                     /locus_tag="VYN42_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1462852.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWKGQLRHIHLEK"
     gene            5432..7345
                     /gene="mnmG"
                     /locus_tag="VYN42_001817"
     CDS             5432..7345
                     /gene="mnmG"
                     /locus_tag="VYN42_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1462853.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         2408 a         1453 c         1750 g         2002 t
ORIGIN      
        1 tcgtcacatg aaacattttt ttgcaggaat tggtgagata aaacttgttg gctacttatt
       61 gtatatatgt gtaggactag cccctctttt tcatatatat gtcataggtt cggaactgag
      121 ttttgtgaaa atagtgttat ctattttggg agttatattt gtaagtatgt taactattgc
      181 tcgaatttat cggacttttc tataaagaat agtttggact tgaactgtat ctaaaaacag
      241 aggttggtcg attatcagcc tctttcttgt cgttgaaaag agtgagatat attgactttt
      301 gaaaaaaatg tcataattga gttgggataa acctaaaagt aatatagtag attgaatctg
      361 gaatagtccg ttatgactgt taaaatattt ctagaaatta atttgacttt cctaatcgat
      421 ttgttcacat cttgtttcaa tctactatac tttctcgtta aaccgttcgg caattcatgg
      481 tgacatggac acatagtagt aagcacacta tgtggcttgg cagagctaaa aactgttccc
      541 ttgcgataag cctaataagc acaacatagg gagttagaga agccgactct aatcaaccac
      601 tttgggcagt agtgagaact gccccgtgct tttttatttt gagaaaatat ggagtttgtc
      661 gttgaaatta cttgattgta ttttggacta tcaagaaaga ttcaatggaa aaacatgtca
      721 agtatcaacg aattataagt atttagagac tttcaaagtg aatttttgct tgactgattt
      781 acatcattta tttgacttat acaaaatcac acgagattat gctagtcaaa caaaacctgc
      841 tattcaagct ggtgttttta ttttagaaga ttttagaaat atcctatgta caatgatgta
      901 atcgaaagga tatctttatg tgagtttatc ggcgatattt tctattctaa aataacaagt
      961 tgttgcatcg tagctaagga tttatctaaa aatactatga aattggacgt catatttttt
     1021 gaggataaaa ataaaagatc cgcagtttta ggtttacgaa gagacaaaag cggagtattt
     1081 aaaccagtta ccctacattt tacaagcgct aagaaatatg ctaaagttcg taaaacagat
     1141 gtgaaggaaa tgaaatggct ataaagattg tccgcaggct taagcttgcg ttttttgttg
     1201 tttaacgaaa ttaaaaaaac aagctctctc atcggaaatg tttttatagg aatgaaggaa
     1261 gatgatgcta tgtttaaaaa gagaatcgaa aagggcaaaa gtagtgtctt tatctttttg
     1321 gagtagaagc ttatgatata gaaatttgta ataaaaatgt aatataaaac atttgacaaa
     1381 tatttacggg gggagtatac ttaatataag tatagtctaa aaatgactat cagaaaagag
     1441 gtaaatttag atgaataaga aaaaaatgat tttaacaagt ctagccagcg tcgctatctt
     1501 aggggctggt tttgttgcgt ctcagcctac ttttgtaaga gcagaagacg ctcccgtagc
     1561 taaccagtct caagctgaga aagactacga tgcagcaatg aaaaaatctg aagctgctaa
     1621 gaaagaatac gaagacgcta aaaaagtttt agctgaagca gaagctgctc agaaaaaata
     1681 tgaagacgat cagaagaaaa ctgaagagaa agcagagaaa gcaaaagcag cttctgaaga
     1741 gatagctaag gcaacagagg aagttcaaaa agcggtccta gattatataa ctgctatcag
     1801 aaatcacaac gaaagtggga aaaaatccgc agaagaagct gagaaaaaag ctaaggaacg
     1861 cgaaactgct gcgaggaaga aatttgatac tattcaaaca acaatagtag ttcctgaacc
     1921 agatgagtta gctaaaactc agaaaaaagc agaagaggct gcaaaaaata aaccagaact
     1981 tactaaaaaa ctagaagaag ctaaagtaaa attagaagaa gcggagaaaa aagctactga
     2041 agccaaacaa aaattggatg ctgaagaagt tgctcttcaa gctaaaatcg ctgagttgga
     2101 atatgaagtt cagagactag aaaaagagct cgaagagatt aatgagtctg attcagaaga
     2161 ttatgctaaa gaaggtttcc gtgctcctct tcaatctaaa ttggatgcca aaaaagctaa
     2221 actattgaaa cttgaagagt tgagtggtaa gattgaagag ttagacgctg aaattgcaga
     2281 acttgaagtt caacttaaag atgctgaagg aaacaataat gtagaagcct actttaaaga
     2341 aggtttagag aaaactactg ctgagaaaaa agctgaatta gaaaaagctg aagctgacct
     2401 taagaaagca gttgatgagc cagaaactcc agctccggct ccagccccag ctccagctcc
     2461 agctccagct ccaactccag aagccccagc tccagctccg gctcctaaac cagctccggc
     2521 tcctaaacca gccccagctc cagctcctaa accagctccg gctcctaaac cagctccagc
     2581 tccggctcct aaaccagaaa agccagcaga aaaaccagct ccagctccta aaccagaaac
     2641 tccaaaaaca ggctggaaac aagaaaatgg tatgtggtac ttctacaata ctgatggttc
     2701 aatggcgaca ggatggctcc aaaacaacgg atcatggtac tacctcaaca gcaatggtgc
     2761 tatggcaaca ggttggctcc aaaacaatgg atcatggtat tacctaaatg ctaacggtgc
     2821 tatggcaaca ggatggctcc aaaacaatgg ttcatggtac tacctcaaca gcaatggcgc
     2881 tatggcgaca ggatggctcc aatacaatgg ctcatggtac tatctaaacg ctagcggcgc
     2941 tatggcaaca ggttgggcta aagtcaacgg atcatggtac tacctcaacg ctaacggttc
     3001 aatggcaaca ggttggctcc aatacaacgg atcatggtac tacctcaacg ctaacggtgc
     3061 tatggcaaca ggttgggcta aagtcaacgg atcatggtac tacctcaacg ctaacggttc
     3121 aatggcaaca ggttgggtga aagatggaga tacctggtac tatcttgaag catcaggtgc
     3181 tatgaaagca agccaatggt tcaaagtatc agataaatgg tactatgtca atggcttagg
     3241 tgcccttgca gtcaacacaa ctgtagatgg ctatgaagtc aatgccaatg gtgaatgggt
     3301 ttaagccgat taaattaaat catgttaaga acatttgaca ttttaatttt gaaacaaaga
     3361 taaggttcga ttgaatagat ttatgttcgt attctttagg tacctatctt atgatttcag
     3421 gaaatgtcat taaaaaaacg actccttttc tctaacttga aaaatagatt agagaaaatg
     3481 ggttgtttta tttattatag ttatttgaat gaagataaga agaaggtata ctcacatcat
     3541 tcacataatc tgtatgttga ctataagttt taaaaaacaa tttttaagct cttccttgtc
     3601 ttctccaacc aagcgtgtta taatgagtac tgctcaagcg accttcaatc gtgaagcaca
     3661 cacgaccttc aatcgtgaat aaacgaatag atgggagact taccatgagt gataactcta
     3721 aaacacgtgt tgtcgtgggg atgagtggtg gtgttgattc gtcggtgacg gctcttttgc
     3781 ttaaggagca gggctacgat gtgatcggta tcttcatgaa gaactgggat gacacagatg
     3841 aaaacggcgt ctgtacggcg accgaagatt acaaggatgt ggttgcggtg gcagaccaga
     3901 ttggcattcc ctactactct gtcaattttg aaaaagagta ctgggaccgc gtttttgagt
     3961 atttcctagc ggaataccgt gcagggcgca cgccaaatcc ggacgttatg tgcaacaagg
     4021 aaatcaagtt caaggccttt ttggactatg ccatgacctt gggggcagac tatgtagcga
     4081 ctgggcacta tgctcgagtg gcgcgtgatg aagatggcac tgttcacatg cttcgtggcg
     4141 tggacaatgg caaggaccag acctatttcc tcagccaact ttcgcaagaa caactccaaa
     4201 aaaccatgtt ccctctggga catttggaaa agcctgaagt acgcagacta gcagaagaag
     4261 caggcctttc gactgctaag aagaaagact cgacagggat ttgctttatc ggagaaaaaa
     4321 actttaaaaa ctttctcagc aactacctgc cagctcagcc tggtcgtatg atgactgtgg
     4381 atggtcgcga tatgggcgag catgctggtc tgatgtacta tacaatcggt cagcgtggcg
     4441 gactcggtat cggtgggcaa cacggcggtg acaatgcccc ttggttcgtt gttggaaaag
     4501 atctaagcaa gaatattctc tatgtaggac aaggattcta ccatgattcg ctcatgtcaa
     4561 ctagcctaga agccagtcaa gtccacttta ctcgtgaaat gccagaagag tttacgctag
     4621 aatgtacggc taaattccgt taccgtcagc ctgactctaa ggtgaccgtc catgtcaaag
     4681 gagacaaggc agaagttatc tttgcggaac cacaacgcgc gattacacca ggacaggcag
     4741 ttgtctttta cgatggagaa gagtgtctag gtggcggttt gattgacaat gcttaccgcg
     4801 atggacaagt ttgtcagtac atttagattg acaaattttc tcaatttgct acaataataa
     4861 cagcaataga aatgatggtc aaagctcatg gatgttgcag gcttttttgt cctgcacttc
     4921 tttgtagttt tgactgtttt tgtgtcgttt aagggaaagg acaagaatga ctcaacaaga
     4981 ctttcggaca aaagtagaca atacggtttt tggtgttcgg gcgacagctc tgattcttca
     5041 aaatcgcaag cttctagtca ccaaagacaa gggcaagtat tacactatcg gcggtgcgat
     5101 tcaagtcaat gaaagcacgg aagacgcggt agtccgtgaa gtgaaggaag aactgggtgt
     5161 caaagctcaa gctgggcagc tagcttttgt ggttgaaaat cgttttgaac aggacggtgt
     5221 ttcctatcac aatatcgaat ttcattatct ggtagactta ctggaggatg ccccattgac
     5281 catgcaggaa gatgagaaaa ggcagccctg tgagtggatt gacttggata agcttgagga
     5341 tatccagcta gttccagctt ttttaaaaac ggccctacca gattggaaag gccaactaag
     5401 acacatccat cttgagaaat aggagagaaa tatgacatat cattttactg aagaatacga
     5461 tattattgta attggtgcgg gacacgctgg ggttgaggct tccttggccg ctagccgtat
     5521 gggctgtaag gtcctgcttg cgaccatcaa tattgaaatg ctggctttca tgccttgtaa
     5581 tccctctatc ggtggttctg ctaaggggat tgtcgtacgt gaagtcgatg ccctcggtgg
     5641 cgagatggcc aagaccattg acaagactta catccagatg aagatgctca acacagggaa
     5701 ggggccagcc gttcgtgccc ttcgtgcgca ggctgacaag gaactttact ctaaggaaat
     5761 gcgcaagaca gttgaaaacc aagaaaatct gacccttcgt caaaccatga ttgatgagat
     5821 tttggtggaa gatggcaagg ttgtcggtgt gcgtacagcc acccatcaag aatatgctgc
     5881 taaggctgtt attgtgacga cagggactgc tctccgtggg gaaattatca tcggagacct
     5941 caagtactca tcaggtccta accacagctt ggcttctatt aacctagctg ataatctcaa
     6001 ggaactgggc ctcgaaatcg gtcgtttcaa gacaggaacc cctccacgtg tcaaggcttc
     6061 ttctatcaac tacgacgtga cagaaatcca accaggagat gaagcgccta atcacttctc
     6121 atacacttca cgtgatgagg attatgtcaa ggaccaagtg ccatgctggt tgacctacac
     6181 caatggtacc agtcatgaga ttatccaaaa caacctccac cgtgcgccta tgtttacagg
     6241 tgtggtcaag ggagtggggc ctcgttactg tccgtcgatt gaagacaaga ttgtgcgctt
     6301 tgcggacaag gaacgtcacc aactcttcct tgaaccagaa gggcgcaata ctgaggaagt
     6361 ctatgtgcaa ggactttcaa ccagtctgcc tgaggatgtc cagcgtgact tggttcattc
     6421 catcaaaggt ttggaaaatg cagagatgat gcggacaggt tatgctattg agtatgatat
     6481 ggtcttgcct catcagttgc gtgcgactct ggaaaccaag aaaatctcag gtctcttcac
     6541 tgctggtcag acaaatggaa cgtcaggtta cgaagaggca gcaggccaag ggattatcgc
     6601 gggtatcaat gcggctctga aaatccaagg taagcctgag ttgattttga agcgaagtga
     6661 cggttatatc ggggtgatga tcgacgactt ggtgaccaag ggaaccattg aaccttaccg
     6721 tctcttgacc agtcgtgctg aatatcgtct cattcttcgc catgacaatg ctgatatgcg
     6781 cttgactgag atgggacgcg agattggcct tgtggatgat gaacgctggg ctcgttttga
     6841 aatcaagaaa aatcaatttg ataatgagat gaaacgccta gacagtatca aactcaagcc
     6901 agtcaaggaa accaatgcta aggttgagga aatgggcttc aagccgttga cagatgcggt
     6961 gacagccaag gaattccttc gccgtccaga agtttcttac caagatgtgg tggccttcat
     7021 cggaccagct gcagaagact tggatgacaa gattatcgaa ttgattgaaa cagaaatcaa
     7081 gtacgaaggc tatatttcaa aagccatgga tcaggttgcc aagatgaaac gtatggaaga
     7141 aaaacgcatt ccagccaata ttgactggga tgacatcgat tctattgcga cggaagctcg
     7201 tcagaagttc aaactcatca atccagaaac catcggccaa gccagccgta tttcgggggt
     7261 aaacccagca gatatttcta ttttgatggt gtatctggaa ggtaaaaatc gtagtatttc
     7321 taaaactctt caaaaatcaa aatgatacgt cgtcggcttc ttacgaatga gttcaaagct
     7381 tggctttgat tcatctccag cctcccatag tttcccgaac tatgggagct aactcaagtt
     7441 atgcattttc ctagccttct ggtctgattt tcattgagtt ttaatctcaa aagaaagcat
     7501 agagaaaaac agctccgaag acggggctgt tttgttgact tgtactcaat gaaaatcaaa
     7561 gagcaaacta ggaagctagc cgtaggttgc tcaaagcact gctttgaggt tgt
//
LOCUS       DAVLUM010000083         7593 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLUM010000083 DAVLUM010000000
VERSION     DAVLUM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.083"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            410..571
                     /locus_tag="VYN42_001818"
     CDS             410..571
                     /locus_tag="VYN42_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462854.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            663..2342
                     /locus_tag="VYN42_001819"
     CDS             663..2342
                     /locus_tag="VYN42_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1462855.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRSQKAMEGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCTKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            2610..3176
                     /locus_tag="VYN42_001820"
     CDS             2610..3176
                     /locus_tag="VYN42_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462856.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            3498..3686
                     /locus_tag="VYN42_001821"
     CDS             3498..3686
                     /locus_tag="VYN42_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1462857.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3748..4506
                     /locus_tag="VYN42_001822"
     CDS             3748..4506
                     /locus_tag="VYN42_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1462858.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYPGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVSDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            4564..5418
                     /locus_tag="VYN42_001823"
     CDS             4564..5418
                     /locus_tag="VYN42_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1462859.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            5530..6414
                     /locus_tag="VYN42_001824"
     CDS             5530..6414
                     /locus_tag="VYN42_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1462860.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            6577..7281
                     /locus_tag="VYN42_001825"
     CDS             6577..7281
                     /locus_tag="VYN42_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV1462861.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMNYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDSVAWVRQGIF"
BASE COUNT         2695 a         1045 c         1604 g         2249 t
ORIGIN      
        1 agaattttgt tacatcaaga taaatatttt ctgatggtca aattttaaaa agattaataa
       61 ctctcgataa attttgaacc ttaacaattg aatagaccaa gacaagacgt taattatttt
      121 tggagcgtaa taacctatcc gtcaagatct ttcggctgaa taattcggca aaaaaagttc
      181 tgctaagcaa aaagaaagtg agcgataagt aagagtttga atatagggag ggatacccta
      241 tccgctatga agaaaatgag gataatgata cttctaaggt tgaagccggc tcatccggaa
      301 tagaggcgga ggtgagattc ctatgttgct aatccaaagc acttgtcaat gtcaaaaaac
      361 ttaattaaac aaataattat tagatataaa actttagagg aggtatatat tggacaatga
      421 ctggaatgga ttggctgatt taatagcaaa tctgattgca aaatatgctg gtgctttaga
      481 tttagataat ctacccgatc caacgccagc aaaaaatcaa gagatgaaaa atagttttga
      541 catggcaaaa acacaaattg agacggacta ataaaagtgt tataatatac ttgaaatgat
      601 agtccaaact taaattaaaa aaattatata tgatatagaa aaattatatt gaggttaata
      661 ctatgtcaaa agaaaaaata aaagtatacc tctatacacg agtatctacg tcaatacaga
      721 tagaggggta ttcgttagag gcacaaaaat cacgaatgaa agcttttgct atttacaacg
      781 attatgaaat tgttggagag tatgaagatg ccgggaagtc tggcaagtct attgaaggta
      841 gaatacagtt caatcgaatg atggaagata taaaatctgg aaaagatgga gtatcttttg
      901 ttcttgtgtt taagttatca agatttgcaa gaaatgccgc tgatgttctt tctacacttc
      961 agataatgca ggattatgga gttaatctta tctgcgttga agatggcatt gattcatcta
     1021 aagatgctgg gaaactaatg atttctgttt tatcagctgt ggctgaaata gaaagagaaa
     1081 acatccgtat tcaaacaatg gaaggtcgca gtcaaaaagc aatggaagga aaatggaatg
     1141 gtggttttgc tccgtatgga tataaacttg aagacggcaa gctgtttata aatgaggaag
     1201 aggcagttgc aataagaacg attttcgacc agtatgtaaa tactacgata ggagccaatg
     1261 ggatatctaa atacttagag aatcatggaa ttagaaaaat cccaagacag aatggtaaga
     1321 atcctttgtt tgatgcaggt cttataagaa agatattaaa gaatcctgta tataatggga
     1381 aaatagcatt tggaagaaga actttagaaa aagttcatgg tacaagaaat gaatataagc
     1441 aggttgaaca agatgaatat ctaatatctg aagggataca tgaagctata gtttccgatg
     1501 aagtttggca agctgctcag gttaagctaa aatctcaagc aaagaaatat gagcatgtga
     1561 ataaaggaaa agatacacgc acacacttgc tttctggaat tgtaaaatgc ccgatatgtg
     1621 gagtgggaat gtttgggaac aagtgtacca agaaaaagaa agatggcaca aagtataaag
     1681 atttttatta ctatggttgt aaacataggc agatgataag aggtcataag tgtacattca
     1741 gtaagcaaat tagagaagaa ttgttagatg atgctgttgc agaggtgatt gtcaagatag
     1801 taagtaatcc gaaatttgct tctatgatgc aagaaaaaat caacatgaag gtggatacct
     1861 ctgaaataga aaaagaaata gataattacc aaaaggaatt gagaaagagt cattctacaa
     1921 agtttaagct aattgaggaa atagataatt tagatgttga agataagcac tataagagaa
     1981 ggaaacagga tttagatgat agactatatc gtatgtatga caaaatagat gaattagaat
     2041 catcactaat tgatgcgaaa gcaaagaaac agactattga agctgaaaaa cttacaggag
     2101 ataacatata taaggttctg atctattttg ataagctcta taaagtcatg aatgatgtag
     2161 agcgtaggca gttaatttca gctttgattt ctgaaattca agtttatgaa gaaaaacaat
     2221 ctaacggaca atggctaaaa tccattactt ttaagctacc aattatagaa gaaaatctca
     2281 acatagattt ggacaatgat gaacaagttg aatgtgtaag tttattagag aaacgtagtt
     2341 aatcctcaaa aggttcccca aactttttga gtcccactga cgcatcacgc tgaggcggta
     2401 tcactgcttg tacgagttga agcatcagcg aagtaaaagt agatgttcag ccaatgcgac
     2461 gaggtgagac cgaaggtcga taaggtgtgt tctgggtata ggactcgtaa agtaagtagg
     2521 aaatatgatg agatgataca gagagcctga attggtcagg tgacgtgctt atgtacatta
     2581 gcctgataat gaaaatggag agattatcga tggttatatt ggaattgtac caaaatgatt
     2641 attctaaaga tttagtagca tttgattcca tagaagatgg gaaagccttt gtagctcaaa
     2701 tcccgggata cactctggaa acagaagatg gttttgaagt ggagtatttt aatcctaaaa
     2761 acataccgga ttatatggaa attattttta acggaaatat tgttccttta tctaaattta
     2821 tgttcgatcc tgaggaaaat gtaaacatta tttggaaaga gatttcaaat ttatccctca
     2881 aaaatgatag agtgatcgaa ggatattcaa aaattgatgc atatgtcgtt aacaaccatg
     2941 aagttaaagc ctatgtcgaa acaagagaaa cgaactatcg taaagcaaaa gacttcttag
     3001 aaagccgcgg atatgaaatc gacagaagct ttttcggaag tgaagacggt gaagcgattc
     3061 tttacagaaa aaaagggatc gaagtttggc atttcttgtg tcacttagac ccaatgtttg
     3121 tagagattga agatgtagaa ggatatgtta aagaagaagt tggagagatt caatagtcaa
     3181 ccaaagttcc ttgtgagtat atacctttgc tagtaaaaga gtcaaaacgt tataacgaag
     3241 gggggtaaga aaacccttga gtgtaagtct ttttcttgtt tagagggaaa gtattagagt
     3301 agccgctcat aatttatact agatttgata actgatttga gacagatttt atttctataa
     3361 atattgtgaa aattttttaa taccaaagat ttaaagttac tgtgtaaaaa atcctctcca
     3421 cttttaaact aatgtattat aaaagccagt tgacacaagt gttacacctg tgatagaatt
     3481 aacttgaggt gatgaaaatg gcaaccgata aaaatagaat aatgattagc ttggatgata
     3541 aaaatctaga gaaacttgaa aatttagtag aagatgctag agatagaagg ggaatgcgac
     3601 taacaaagtc ccaggttatt gaattactcc taaataccgt tgattatttc gatgatatta
     3661 tgggggctat ttactcaaaa aaataagagc aaaattgcta ttatttttta caaattggtg
     3721 taacactagt gatataggag tgatgaaatg gttgtttata ttagacaaag taaattacca
     3781 agtgaggttt caattaataa atacaatgct caagtaggtg cctacttaca aggagaagaa
     3841 gttattttat atcaatcttt ttctgaaata aaagagttaa caagtgaaga tatagttgta
     3901 gattatataa tggagactag agcattacta aaaatgatgg gcttaaacgt tccggttcat
     3961 gactatccta ttgagcttaa agagttttat ggtcgaaaga tttatcctgg tattttagga
     4021 gagattgtga atatacctga taattgggga aaatttatta agcctaaagc tggttcaaaa
     4081 gtctttactg gaagagttgt taatggaacc catgatttaa taggtattgg tctacctttc
     4141 gactatccta tatggattag tgaggttgta gaattcatag ctgaatggcg ttgttttgtg
     4201 ttagatggtc gcgtattaga tgttcgaccc tatacaggtg attatcatgc acaatttgat
     4261 gcaagtgtaa gtgatgaagc gatatcatgt tggaaagatg cgccaatagc ttatggacta
     4321 gatatcggtg ttactcgcga tggcagaaca cttgttgttg aagtaaatga tggttatgca
     4381 ttgggaaatt atggcctatc tcctttaaaa tcaatcaatt ttcatagagc taggtggaaa
     4441 gaaatggtaa aaccctattt tgaaaaaaat gaaattttta aaatccaaca ggatgttatt
     4501 ttctaaaata aatatggtag ataaccaata taaaaagcat caaaatgaac aaggaggaat
     4561 ctgatgcttg gagcaattat tggagatatt gtcggttctg tttacgaatg gaacaatatc
     4621 aaaacaaagg actttccttt atttcggaag gactgctttt ttacagatga cacggttatg
     4681 acctgtgctg ttgcagaagc aattatgaat ggtggacaaa aagacgactt cattgacgcg
     4741 atgaagaaat atggcagaat gtatccgaat gctgattacg gtgctcggtt taatgcatgg
     4801 ctaaacagcg ataaccgtga gccttataat agctttggga atggatcagc tatgcgtatt
     4861 tctccatgtg cttggatcat ggactgtggt ttttatgcga aaactggtat atggccatca
     4921 tctagaggac ttacgagtct ttctgcagag gtaactcata atcatccaga aggtgtcaaa
     4981 ggcgctatgg ctacagctga tgctatcttt ctatgtcgtt tttactttgg tggttattgt
     5041 agagagtacg agcaatcaat taacgacaat cctacagagt gtaaaagacg aattaaggat
     5101 tatatagaaa aagaatacga ttacaatcta tctcaaactt tagatgaaat ccgtcctaac
     5161 tatcgtttta acgaaacatg tcaggaaact gtccctcaag ccattatcgc ctttcttgaa
     5221 agtagagact tcgaagatgc gataagaaat gccatctcac ttggtggcga cagtgatact
     5281 ctcgcagcaa tcacttgtag catagcagag gcagcttacg gtattcctga ttggatcaag
     5341 gataaggcct attcttactt ggatgaaccc ttaaaggatg tagttaggcg atgggaaaat
     5401 agaataaaag cgtattaatc tccagtacgt cagatttctc ttttctgtat tttcattgta
     5461 taataggatt acatttactt gcatacgacg aaatgtaaac atttctgttt aaaattaagg
     5521 ataaaatcaa tgaaaaaagc aatggtaatt atcaacccta cttctggtgg cgagaaggct
     5581 ttggattaca aagaaaagct ggaaaataaa gcaaaagaat actttgaata tgttgaaacc
     5641 aaaattaccg aaaaagcgct ggatgcaaca cattttgctg aagaagcttc tcgtgagcag
     5701 tatgatgcag tggttgtgtt tggtggagat gggactgtca atgaagtcat ttcaggtatt
     5761 gatgagagag actacattcc taagttaggg attatcccag gcggtacggg taacctcatt
     5821 acaaaacttt tggaaatcaa tcaagacatc gatggcgcaa ttgacgaact ggattttgat
     5881 ttaaccaata agattgatat cggtaaagca aatgacaact attttggtta tatctttagt
     5941 atcggttctc tgcctgaggc gattcacaat gttgaaatag aggacaaaac aaaattcggt
     6001 attttaacct atgctgtaaa taccatgaag tctgtcatga cagatcaggt ctttaacatt
     6061 aaggttgaga cagaaaatgg aaattatgtt ggtgaagcta gccatgtttt ggtccttttg
     6121 acaaattact tcgctgataa gaaaatcttt gaagaaaaca aggacggcta tgccaacatt
     6181 ttgattctga aagatgcctc tatattctcc aaattatccg tcattcctga tttattaaaa
     6241 ggggatgttg tcgcaaatga taatatcgag tatatcaaag cgcgtaatat taaaatctct
     6301 tcagatagtg aattggagtc agatgttgac ggagataaat cagataacct acctgtagaa
     6361 atcaaagtcc tagctcagcg agtagaagta ttttcaaaac cgaaagagga ttagtatata
     6421 gagaaagcct tttttaaggc tttttgtata ctttaaaaga tagttccttt aacaacggac
     6481 attccttgca aatagtttac aaaaatagta tactggattt attgagtttg aaaacgtttg
     6541 cgtaaaattt ggatgaatac tttaggagac aaattgatgg aattgagtgc tatttaccat
     6601 aggcctgagt cggagtatgc ctatctttat aaggataaga aactccatat tcgaattcga
     6661 actaagaaag gggacattga aagcatcaac ttgcactatg gggacccttt tatctttatg
     6721 gaggagtttt atcaggatac aaaagaaatg gtcaagataa cttctggtac cttatttgac
     6781 cattggcagg ttgaagtgtc agttgacttt gcacgtatcc agtatctctt tgagctcaga
     6841 gatacagaag gtcaaaatat tttgtatggc gataaagggt gtgtggaaaa ttctctagaa
     6901 aatcttcatg caattgggaa tggatttaag ttgccttatc ttcatgagat tgatgcctgc
     6961 aaagttcctg actgggtttc aaatacggta tggtatcaga tatttcctga aagatttgcc
     7021 aatggcaatg ctctattaaa ccctgaaggg actttagact gggattcatc tgtcacacct
     7081 aagagcgatg atttctttgg tggtgattta caggggatta ttgatcatat gaattacttg
     7141 caagacttgg gtattactgg actatatctt tgtcccatct ttgaatctac aagcaatcac
     7201 aagtacaata cgacagatta ctttgaaatt gaccgtcatt ttggagacag tgttgcatgg
     7261 gtgcggcaag ggatttttta gaactaatta atcacaaagg gctacctctt tttaatccgc
     7321 ttgtaggtga ttctcatgta aataatagac aagaatatga caatacaggg agtggaaatt
     7381 tataacctga aaagtggaat gaaactgcaa agcagcttta taatgctata atgtggttga
     7441 ttattttatg gaatgctaag ccggatacac ctttatttaa ttttaaagac gaagtaatta
     7501 agtataaaac atatgagcct tttgaaagca gtataaaaag agtaaatact actataaaga
     7561 atggtagtaa agggaaaact ctgactgaga tga
//
LOCUS       DAVLUM010000084         7412 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLUM010000084 DAVLUM010000000
VERSION     DAVLUM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.084"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            459..684
                     /locus_tag="VYN42_001826"
                     /pseudo
     CDS             459..684
                     /locus_tag="VYN42_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            850..1143
                     /locus_tag="VYN42_001827"
                     /pseudo
     CDS             850..1143
                     /locus_tag="VYN42_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167986.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(1368..2873)
                     /gene="pyk"
                     /locus_tag="VYN42_001828"
     CDS             complement(1368..2873)
                     /gene="pyk"
                     /locus_tag="VYN42_001828"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1462862.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(2932..3939)
                     /gene="pfkA"
                     /locus_tag="VYN42_001829"
     CDS             complement(2932..3939)
                     /gene="pfkA"
                     /locus_tag="VYN42_001829"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1462863.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            complement(4021..7122)
                     /locus_tag="VYN42_001830"
     CDS             complement(4021..7122)
                     /locus_tag="VYN42_001830"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1462864.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGQSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
BASE COUNT         2256 a         1619 c         1284 g         2253 t
ORIGIN      
        1 caactataaa acaatataga ctagtaatgg ttggactcaa taagaattgg gtactaagat
       61 aggtataagt aaaaacacca ttagaaatta tgaaaaaagg gttaggtcta ctaagaaaaa
      121 tactatattt gacttagtta aagtattcag tagcttgatc gatgccctct ttcctccagt
      181 tcaaaaggat tctcctagcg atatccaatc tatctacgac caacgggaac cacccagaca
      241 aggtaaagtt ctgacctatg ccgagaggca actgtatgat cagaaaaacg aagtatcgta
      301 aaaatcatca gactggacga ctacagacag actacttact ctcgtgttag gtagtttatc
      361 tctgcaggta gccgctcgat gcaggacaac gatttagata tggagtttcc attatcccag
      421 acgactacga cccaatcgct tatgtcgtca gcaagtccat ggagccaaag ataagaaaca
      481 gcgactacct atttatcaag aataccccac agattgacta taataccatc ggcatcttcc
      541 aagtagacgg cactaactat gtcaagaaac tccgccaagg ctacctcaaa aaaactcaat
      601 cccgaatact ccgacatcca cctagacgaa agcaaccata ttcgtaccat cgggaaagtt
      661 gtcaggctat atagggagaa ttaaaaaagg gggagaatgg cgatataaaa caaacagatt
      721 ttaaaagatt cgaaaaactt tgaaaaagtt cattctacat ttcaaaaaaa gaataagtga
      781 cctaagatag attagatttt gttaaacaat agtgatatgt aaatttagag aaaggcattt
      841 aagatcactt tgcaaaaggc aaatactaaa ctagagaaac cgataaacca gccccttagt
      901 tcccatattt tcaggcacac actccttagt acactagctg agaagaatgc tataatggtt
      961 agagtggaac acaaaaacgc taaaacagta aataacatct acactcacgt aagtaaaaga
     1021 atggagtaag ctactttgga ggttttaaat accatatcat taaatcgaaa atatatcaga
     1081 tcgaatctag acaagtacat tacgattgct aaaacatttg tagaaattca tttgactttc
     1141 taatcaattt gtgcatatct tatttcatac tcaatgaaaa tcaaagagca aactaggaag
     1201 ctagccgcaa gctgtacttg agtacggtaa ggcgacgctg acgtggtttg aagagatttt
     1261 cgaagagtat caatccatta tgaaagtttt gcctatttct taccctctat acaaaaagcc
     1321 tatcacacaa gctctaaagc tggatatgat aggtttttat atttttctta acgtactgtg
     1381 cggatacgca ttgtgtttgt gcgaacagct tctcctactg gcacaccagc aacgataacg
     1441 atatcatcgc ctgactcaac gagacctgct tctaccgctt tacgttcagc gatttcgaac
     1501 atatcgtcag ttgaagatgg agcatctgtc aacattggga taacacccca gttcaacatc
     1561 aagccacgtt ctgtcaattc gtcaaatgtc aatgctaaga tatcagcatt tggacggtat
     1621 ttagaaatca aacgtgcagt atgacctgtc ttagtaagag ttacaaccaa tttgatatcc
     1681 attgagctag tagcatcttt aacagcagaa gccattactt ctgtcttaga gttacgctca
     1741 aatgaatctg aatcaagacg tccgtattca ttaagaagag cttgagcgtt cttgtcgatt
     1801 gtagccattg tagttactga ctcgagtggg tatttaccgt ttgcagactc gcctgacagc
     1861 attgtagcgt cagttccgtc gataacagcg ttgaatacgt ctgatacttc tgaacgagtt
     1921 gcacgtggtt tttcagtcat tgtttcaagc atgtttgttg cagtgataac aactttacct
     1981 gcagcattga ctttcttgat aatcattttt tgataaactg gaaccatttc gaacggtact
     2041 tcgataccca tatcaccacg agcaatcata ataccatcag ctgcttcgat gatttcgtct
     2101 aagttatcga taccttgttg gttttcgatt ttagcgaaca attgaacatg tccgtttcca
     2161 gtttcttcac agattgcacg aacttcgttc acatcttttg cagtacgtac gaatgaaatt
     2221 gcgatgaagt tgataccttg ttcaagaccg aaacggatat cgtcgttatc gcgttcagca
     2281 agagctggga aaggaatttt agtgttaggg atgttcacac ctttttgttt agcgatgata
     2341 ccatcgtttt caacttcaac ttcaaattca cgagttgcat catctttagc aaccacacga
     2401 agaccaagtt taccatcgtc aaccaaaact tgacgaccaa cttcaacatc atcatagata
     2461 tcaagagcac cagcaacgtt caacgcaatc acttcacgag ttgatttgat tccttgttta
     2521 gttgcaacac gaattttttc accagttttg tatgaatatt ctttagcttc accttcgaac
     2581 aattctgtac ggatttcagg tccttttgta tcaagaagga aaccaacttt tttacctgca
     2641 attttttccg caagtttaac agttgccata cgctcacctt gttcttggtg gtcgccgtgt
     2701 gagaagttga atcggaatgt gttagcacca gcttcaatca atttagcaat gtttttagct
     2761 gaagcttcaa catcaagttt ttcaccccag tatccatcct caccgaattt tttaccacca
     2821 cggatttcta ccgcaggacc caaagttgca acgatcttta cacgtttgtt catgattttt
     2881 gtgactcctt tatatatatg acctttttgg tcttattaac taaattgtaa attatgacaa
     2941 gctcttattc aagctagata gctcaatatc ggctttgtgc gggttgttaa ccacaatctt
     3001 accttctgca gtaaggctaa acaatgcccc ttcttctgca gtaccaagaa ttggattttc
     3061 aaccattttt tcgttacgaa taccaaccgc aacaccaccg ataccttctt taagaagttt
     3121 aacagcatgt gcacccatac gtgacgccaa aacacggtca cgcgcagttg gagaaccacc
     3181 acgttgaata tgtccaagtt ctgttacacg aaggtcgctt gtatctccag cttctttaag
     3241 tttttgacca aattcagccg ctgacatcac accttcagct aagacgatga tattgtgttt
     3301 tttaccacat tcataaccag ctttgatgct tgctacgata tcttccatct tgaagcctgc
     3361 ttcagggatg atgatttcat cagcaccagt tgcaatacca gcccaaagag cgatatcacc
     3421 agcgttacgt cccataactt cgattacaaa agtacgacgg tgacttgatg atgtatcacg
     3481 aatcttatcg atagcgtcca tggcagtagt aaccgctgtg tcaaaaccga ttgtaaagtc
     3541 agtaccaacg atatcgttat cgattgtacc tggaagacca atagctggga agccatgttc
     3601 agtcaaacgc atagcgccgt ggtaagatcc gtcaccaccg ataacaacta caccttcaat
     3661 tccgtgtttt ttcaattgct caatcccttt aagttgccct tcaagttgag cgaactctgg
     3721 gtaacgagct gagtgaagga aagtaccacc acgagaaatg atgtccccta ctgaagctgc
     3781 atctagggga tgaatttcac cggcaaccat accagcatat ccgtcataga taccaaaaac
     3841 ttccattcct tctgaaattg cttgacgaac aactgcacgg atggcagcgt tcataccagg
     3901 ggcgtctcca ccactagtca aaacagcaat acgtttcata ttggttatgc tcctttttct
     3961 tttaacattc ttactgatta taccacattt acgttgaaaa ttcttctatt ttccgtattt
     4021 ttagcgataa atcgttttca taacgatttc attcaatttc tcctctaatt cattggattt
     4081 agctacaaaa tgatggggag aaacgatggt tttctgttcc tcttcatacc ggatgatgac
     4141 tgggattggg cctttaaatt gttctaaaat gcgtgaaatt tcttgatccg attcatgatt
     4201 tttcacctgt atccaaaagc gttcagcaac tgcttctctt atttcttgtg caatcatttg
     4261 cagacggcca tcacgtgatt gtatttttcc ttttacatag tagaaggctc cctcttttat
     4321 ttcctgtcca acctgacgat ataagtctga aaagagagtg acatccaatt ttttcttact
     4381 atcatctgcc tgtaagaagg ccatattttc accctttttg gtacgaatca cttttatttt
     4441 ctgaacttca accaagataa tagcatagct attttctgac aaatttccga ttggggtaat
     4501 cgggtaaata gccttacttg caatagcttg tagtggatgt ttgctgacac ctatccctaa
     4561 aagctcttgt tccatataaa atttttcttg ttccgtccaa tcttccgatt cctgccaact
     4621 ataaatagca tctccaaaca aacttcccaa ctctttcaca aattcaaata gattagctaa
     4681 gttattaaat actttttgac gatttttttc aaatgaatcg aaaagaccaa cttttaccaa
     4741 aggttctagc agaggaagtt tcagataatt ctcaggtaat ttagctataa aatcttcaat
     4801 gttagaataa ggtctatttt caataatcca gagagctaaa tcattactga ctcctttaat
     4861 ggatttcaaa cctagataga tggccttgtt ggcaatttta tcgtgatagg gaatggtgtt
     4921 gatggataga gaggctactt caaaacctgc ttcaagtgca tctattaagt aatcactgtt
     4981 ggaagaattt aacatgacct gataaaaaat ggctggataa tgcgttttga aataagccaa
     5041 ctggaaggcc aaggctgagt aggcataggc gtgtgacctg ttaaaaccat aacctgcaaa
     5101 cttctccata acatcaaaga cctgctctgc tttttccaca gtatgaccag cttctaatga
     5161 accttgaata aaggaagccc tcatctcatg catggcagag gcatcctttt tccccatagc
     5221 ccgacgcaaa atatcggctt tcccaagact aaatccggca agtcgctggg caacctgcat
     5281 aacctgctcc tgatagagca ttatgccgta ggttggagcc aaaatatcct ccagtactgg
     5341 atccagaaca gtcacttctt cctgcccatg ctttcttgcc acaaaattat tgatatagtc
     5401 actagcaccc ggtcgattta gagaagtagt cgcgacgaca tcttcaaaac agactggttg
     5461 cacacgctta agcagacgaa tggcacctgg ttgctcaaat tgaaagatac cttttgtatt
     5521 accagaggca aataaagcta acgtttcttt gtcttctaaa tcgatttctt caattttcag
     5581 atgaatacct tctgtttcag caagcaactc ttgcatcttc tggacaaagg tcaaatttcg
     5641 tagtcccaga aagtccatct tcaaaagtcc gctagcctca actccatgag catcatactg
     5701 agtcagtgga atttcatcac catactttag aggaatgtag ttggttaaat cttggtcact
     5761 aattacaaca ccagccgcat ggacagaggt ttgccttgga tagccctcta tcttgcaagc
     5821 aatctcaaaa gctttttggt attctaactt actattgatt tgctgacgaa actggagatt
     5881 gccctcatag gccgacttaa gattgtcacg aaaactgatt ttcttagtaa ttgcagataa
     5941 ttcatactct ggcacaccaa agcgtttcaa gacatctcga agagcttgct tggctccaaa
     6001 ggttgaaaaa gtaacgattt gtgccgcatg tttactacca tatttattac caacatatct
     6061 gataaaatct ggacgataaa tatctgggat atcaatatca atatcaggca tggtatagcg
     6121 ttcacgatta agaaagcgtt caaaaatcag atttttctct actgggtcaa tccccgtgat
     6181 gtctaaggca taagaaacca aactgcctac tgcagaaccc cttcccattc ccatataata
     6241 gccattcgat tgtccaaaac gcaacaaatc ccaaacaacc aagaaataat catcaaagcc
     6301 catatcatga ataacagaca attcttggtc tagtctatct tgatattctt tactagtcaa
     6361 ccccttctga acaagcccca gttcagcacg ctctctcaac tcctctactg ctggtctagc
     6421 tggattaaaa cgaggcagtt tcagactagt atccaagtcg taagaaatgc ctgaaataag
     6481 cttttctaaa ttgtccaaag cttgcggaaa acgctcttgg aatagtttct ctaaagaact
     6541 tgctgatata aagacatctt gtctcgaacg caagggaact tctctgagcg gtagattttc
     6601 tttaatcgct gttaaaactt gaagaacttc tctatccctg ctttcaaaag cgttgacccg
     6661 ataaagaggt aagataggat gatgaaattc gcttgctagt gtttctggat aaacccctat
     6721 atagtaatca cagcctagtt ctaacgactc aactctatca aaataaggca caatgaccgc
     6781 gatatcctcc aggtactggg acaggactga ccaagttttc tccccctgca tcttggctgt
     6841 cgaaagcttc atcaactgct gatagcccac actagataga gctaaaaagc gcaaattcac
     6901 ttcctgatca tctacaaaca ctgtcatttc aagccctagc aaaggatgaa tgccgtattt
     6961 ttttgtaatc tctagaaagt cgaaagcgcc ataaagattg tcaatatcca tcatagccaa
     7021 atgagtgtag ccgtattctt tagctgctct cacatacttt tcgatcgaaa tgacgctttc
     7081 cataaaacta tagactgttt ttgtatctag ttgtgcgatc aatttacact tctcctctat
     7141 ccttctcact atattatacc attttcacct ataaatggct tctcttgaga aaaatttcat
     7201 cagcttacta atttattttc tattcatttg tattttcgtc atcattttta tatttatact
     7261 atattgtata taaaaataga aagcatataa tataaatctc ctagaacttt tataccctat
     7321 ctatttattc ttattgttac tctgttctct atattgaatt tagtgcttta ttcattttta
     7381 ttggattatt tccttttgaa gttaacaatt cc
//
LOCUS       DAVLUM010000085         7299 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLUM010000085 DAVLUM010000000
VERSION     DAVLUM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.085"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(16..1362)
                     /gene="celB"
                     /locus_tag="VYN42_001831"
     CDS             complement(16..1362)
                     /gene="celB"
                     /locus_tag="VYN42_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV1462865.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(1442..1948)
                     /locus_tag="VYN42_001832"
     CDS             complement(1442..1948)
                     /locus_tag="VYN42_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462866.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLALSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(1979..2293)
                     /locus_tag="VYN42_001833"
     CDS             complement(1979..2293)
                     /locus_tag="VYN42_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV1462867.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(2303..4282)
                     /locus_tag="VYN42_001834"
     CDS             complement(2303..4282)
                     /locus_tag="VYN42_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1462868.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(4400..4714)
                     /locus_tag="VYN42_001835"
     CDS             complement(4400..4714)
                     /locus_tag="VYN42_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV1462869.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(4844..5083)
                     /locus_tag="VYN42_001836"
     CDS             complement(4844..5083)
                     /locus_tag="VYN42_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV1462870.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(5135..6571)
                     /locus_tag="VYN42_001837"
     CDS             complement(5135..6571)
                     /locus_tag="VYN42_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1462871.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(6761..7099)
                     /locus_tag="VYN42_001838"
     CDS             complement(6761..7099)
                     /locus_tag="VYN42_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV1462872.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKNLDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT         2466 a         1442 c          972 g         2419 t
ORIGIN      
        1 atactttttt acttattaga taccttgctc ttctttcacc aatttttgat catatacacg
       61 gatgaatgga agatagacta ggaatgctgc aaatgcacat actagagcaa ctaatacagc
      121 tcgaagatct gctgtcccta agaaagctcc aatccctact ggagttggcc atggaacctg
      181 tgcgataatt ggcttaataa agtttagaga attcgctacg taataaatag tagcagtaac
      241 cattggtgct aaaataaatg gtatagccaa ggctggatta tagataatag gtaatccaaa
      301 aattaatggt tcattaatat taaataaggc tggaactaca gatgctcgtc ctattgcttt
      361 aagctgttca gatttagagg caaaagcaat atataaacat agtcctaaag ttgcaccaga
      421 accacctgca attacaaaca tattagaaaa ttcacctgca acagcgaagt gcccgccagc
      481 agcattttca gccatgttag caagagcaat tggactaaca aatgcaaaaa caatgttcgc
      541 accgtggata cctacaatcc aaagtagttg agtcaataga taaataatca ttaaaccaat
      601 ccacgaatta gtcagattgg atacaaaacc aaatggaatt gcaatgactt taaaaatatc
      661 tgttcccatt gctacaagaa gaccgttgat aaagataaca acaaatgcaa caacaaatcc
      721 cggaaccaaa gcggtaaatc cacgagaaac tccttctgga acagcttcag gcattttaat
      781 aacccaatta tgtttaacac acatacgata aataagaaca gtcacaattg ccataatgat
      841 tgcggtaaaa atccctgttg tcccaaaacg tgcgactcca tttcccattg cccatccatc
      901 tgcaattact gcaccttctt ttagacttgt cacagtcttc atcattccac catcaaaaat
      961 gatttgcggt actgtcatga caaaagccat caaggcaagc aaggcaccat taagaggatt
     1021 catattgagt tcttcttcct ctgcataaat ttttgtcaat tcatatgcaa gtgatagaac
     1081 gaaataaaga gatagagaac ccatagtcgc atagtttgca accatgtaaa gtgatgtgaa
     1141 tttatcaaat gaagcagaga aaatatctgc cacaattggc caaaatgaga aagcttgtgg
     1201 caaaatactg aataccaaaa acattgatcc tacaatagta aatggtacag cagccatacc
     1261 tgcagccgtg atagcacgca ctactttaaa ctgagcaagt ttgcccattg gtcccataac
     1321 atggttttca agaaaaccaa acaacccgtt ttgttgatcc ataaatagac ctccttaata
     1381 aaacataata atttttactt tctaaagact ggtttcaaat acaaattata ctagatcagg
     1441 attataaact aagtgagttc ttttccaatt ggacaaattg ttgataagcc ttatctgttc
     1501 gtttataaat ttttttaatt cttctaatgt ctaacaaact cagagctaaa cctaatagaa
     1561 gaactacaaa aacaaataaa cgtgctactt ggttattttc aaaaatcgga aaaagattct
     1621 taaaccaact tgtccaagtt aaaacaagta atcctattga aataagcatt tgtattctaa
     1681 caaacattag tgttattccc aacttttctt tcctatttcc atagagttta aattgttcaa
     1741 cagttgctaa aatagaaaat actatgagca taatggggaa aataataata ggcgagggac
     1801 taataaactg actcaaaagc caataaatat tcccaaaaaa gaagagtgct attgaataac
     1861 gtagaagaag atatcgatta aaaaaagtat tagttagagc catctctcga cgttgttgtt
     1921 caatcttttg tcgttctttt ttatccatat catttcctcc ttatataaca acacatattt
     1981 agttaacttt cttataaaga gctaacattt cctttgctac ttctaataat gtcatagtgg
     2041 tcattaaatg atcttgagca tgtaccatga taatttcaat tttaatttcc actccacttg
     2101 cgtattcttg caagagtttg gtttgtgcat gatgcgcttc aagaattatc tcatttgatt
     2161 gatttaattt actttctgca tcatcaaaac taccttctct catttttgca aatgcttcat
     2221 gtatttctga ccttgcattt cccgaatgca ggataatttc aaatgctgca acctgcagtt
     2281 cctcttgatt catatgaacc tcctatttta tcttctcaaa tatgttaata aaatcttcaa
     2341 agttattgca agatattagc tgattttgca attcatcatt ctctgtcaga gagactatct
     2401 ttttagtcac agttgccaaa ccttcgttcc catatattga tggagataga agaaatacta
     2461 gctggacatg tgaactttga ttatcccaga gtagcgaatc tttacaaatt gcaaccgaaa
     2521 cctttccctc tgtaccaaag ggctgaatag gatgcggaac tgcaattttt tcagaaaaaa
     2581 caactgaact taattcttcg cgctgtttaa ttccataaag taaagattgt tcaaactcat
     2641 ttgattcacc aacagataaa ccctcaacca tcttttcaag taaatttacc ttgtctgatt
     2701 cagtacatat taaaaaattt tctttactaa aatactgtct aaagccgttg ttttcaaatt
     2761 tgttaatctt tgatgattgt acataactag aaacttgcat ctgatccata gcttttctaa
     2821 tcatttccat ctcatcactt ttaagaaaca cactaacttt aaaaactggg atttgaaaat
     2881 atagatttga taaatcaaca gctgacacta taaaatctat tcctttaagt ttttcttgat
     2941 tcaattcata gtagcctatt acatcaacaa cttctactcg cttcccaaac tccgtttcca
     3001 aacgatttct taacatttgg gctgcaccaa atcctgttgc acaaatagca agaatattaa
     3061 acttagtact ctctttgcta cgttccatag cagctaaaaa gtgaagactt acatatgcta
     3121 cttcatcatc tgatattgtc cactccaaga acttgtccat atttgcaaga atttctctag
     3181 tcataaagaa tatatcacta taattctgtt taatttcatc taccaaaggg ttatttaagg
     3241 taatccggct ttctaaacgt acttgtagtg tcattagatg agttatcaat ccttcaatta
     3301 gttggaaatc tgaagaaaag ttatacatat catctaatcc taaattctga aatgttttaa
     3361 ataaagattt ttttaaaact tcttcagaaa tattcttctg atttttttga cattgttgac
     3421 tcttagctaa caaatgcaaa gtaatgtagt ctatttcctg aactggaaat tcctgatttg
     3481 ttacttctct tactttagaa agaattcttt gggcaacctt tctctctatt gcatcatcag
     3541 tcatctgaca gtctatattt tttatttcaa atccggattt taaacgaatc acagacaatg
     3601 ctatgtgaac tactaaattc tgtagtacaa aatcagatag ttttaggttg gcctcttggc
     3661 attcatccaa aacaattcta gcaaattctt ctaatggaac agtttgatca aaaaagttaa
     3721 attttacata gcaatgtatt gttttaaaaa attgattctc taggaaataa tttatgataa
     3781 aacgtcgttt atcacgttcc tcgcctgaga cataaactcc tttattcgcc ctactctcaa
     3841 tggacaaatt atactctgat aacatcactc gtatctttct gaaatcatga gataatgttg
     3901 aacggctaac gtaaagttca tcagctaaat catcaaaaag aactggaact tgctcaaata
     3961 ataatttatt taagataaat actaaacgat catcaccttt tgaaaccgca gttttcgtat
     4021 agtcttcttc cagttcataa gtttgtctaa actcctggta agcgccttga ttctcaaaaa
     4081 atatttgata cccttgacct tgttttgaaa tcaaccggac tccttgaata atcattgtct
     4141 tctcaattaa tttcagtaca ttacggacag ttctatctga acaggataaa tattctgcca
     4201 gttctttgct tgtaacaaaa cgttccttat tttttattaa aaattgaagg atatctttct
     4261 ctttaatgtt taacacattc attccctcct aaaacgtatg ttttcatata ttgaagcata
     4321 ttatacactt aaatcagttt atatcaaact caaaacaatt tatcttaacc taaatattta
     4381 ttgacatttc atgtgttcat caaatattct caagaatcaa attagccatt ttttcaattc
     4441 ccattggaat aggaatatag gcttgaggag gtatttgtac aactggtttt cctgctttag
     4501 aaccagcctc ttcaaattgc ttaaagtaca tttttgtttg agggctgaca agatacaaat
     4561 caaaagctgc tgctgcgata gctttccctc cttcagtagc actaatagca tcaactacaa
     4621 tatctttccc ttttcctttt agaaactctg ttgttttctg tgccataagt gatgaagaca
     4681 ttcctgctgc acaaataatt aaagcttttg ccataatatt ttctcctttt cttaaatcca
     4741 atcaaagctg tgctaagttg gcttatttgt tatctatttt tattataaaa taaagcgttt
     4801 ccaatgacaa ttccctcatt ttcctaaatg atatggaaaa aaattattta tacttcaatt
     4861 tataaaataa aattattcct gagagtagaa atgaaacact atttgctaaa atcaaaggca
     4921 agtctcctat acgaatacca tgagcaagcc acaatgcaat accaataact tgcataacat
     4981 acatacctag agcaatagat cctgtgtcct ttgtcttaac tatacgaaaa acttgtggta
     5041 aaaatgcaaa tgttgttaaa attgctgcaa tacttccaat catatgtcat cccaatatgc
     5101 taaacaaact gagaataatc tcagtttgtt tatactattc tactgattca ccgttagatg
     5161 aaataacttc cttataccag ccaaaagatt ttttcgggga acgattataa cttcccttcc
     5221 cattgtcatc tttatctaca taaataaaac cataacgttt ccgcatttca ccggtaccag
     5281 ctgaaaccaa atcaatacat ccccatggag tataacccat taaatcaaca ccatcttcaa
     5341 ctacagcctt tttcatttca cgaatatggg cacctagata ttcaattcta taatcatcat
     5401 gtaccatacc atctgctgca acttgatcta tagctccaaa accattttca acaataaaga
     5461 gtggtaagtg atagtggtct gtaaaccaat ttaacgcata acgtaaacct tctggatcaa
     5521 tttgccactc ccattcagaa gccttaacat aattattttt cactaaatct tctgtttcaa
     5581 gataatcaaa ataaggatta ttttcacgat gagagtctat agcaaaggac atatagtaac
     5641 tgaaaccaat gtaatctaca gtcccaccaa gtaaatcttc tttatcctgg tcagtaaaat
     5701 caactgaaat accttttcgt tcccaatact tgaaaatatg ctcaggatat ttacctaaaa
     5761 catgcacatc agcaaaataa taacgcttct gcatagcttt cattgccatt aagatatcct
     5821 taggattgca agtaactgga taaattggac acatcgcaat catacaacct atttgaaaat
     5881 ctggattaat ctcatgacca atttttacag ctcgtgcaga agcaactaat tcgtaatgtg
     5941 ctgcttgata cataattgct tctctattat caccttcctc atatacaata cctgagttag
     6001 taaatggtgc aaaatcttcc tgataattcg cttgattatt gatttcattg aaagtcatcc
     6061 aatatttaac cttatctttg taacgtttaa atacgacttc tgcaaaacga gcaaagaaat
     6121 caatcaattt cctatttttc caaccaccat attcggtcac taagtgataa ggcatttcaa
     6181 aatgagatag agtgatgaca ggttcaatac cattctttaa gcattcatca aaaagattat
     6241 cataaaactg taatccttct tcattcggct ctaactcatc accttttgga aagatacgtg
     6301 tccatgcaat agaggtacgg aagcacttga atcccatttc agcaaaaagt gctatgtctt
     6361 ctttataacg atgataaaaa tctatcgcct catgatttgg ataatattta ccctctaaaa
     6421 ctcccaaagt aatttcacga gctactccat gacgaccagc agtcataaca tcagcaacac
     6481 taattccctt gccaccttct tgccatccac cttcaagttg atgagcagca acagcaccac
     6541 cccataaaaa tccatcttta aaagtagtca tcttttttcc tcctgacttt gatactctta
     6601 ttataaacct taaaccaaaa gatgaaaacg cattcttttt ccttattgtt aaggaaagaa
     6661 gtaattttta atggaaatag aacaatatct tcttgtattc tcgtaatgat atctttacga
     6721 ttttcaatac tttcaaacta caaaaactct cacaataatt ctaattccct gtgtctataa
     6781 acgacttatc gctttctggc atcccagaat catcttctat ataacgttca acttgcatct
     6841 gcaagtgata tttttttctt aaatctaagt ttttctgcat tgtctttgat tgataatgtt
     6901 tatctaaagt ttcttgattt atccactgat caataaggag aatagttccc tctttttcaa
     6961 ttggtaaaaa atattcgtat ttcaagttac ctttttgatt tctaatttct ttaacaaggc
     7021 cactatcaag catttctctt gcaaacttta ttgcactatc tccatcacct ttataatata
     7081 catgaatagt caatgtcatc ttatatcctc caaaatcatc cttcaatttt aaaaaaacaa
     7141 gtttagatga ggatctaaac ttgtttttta tgaactaatt atctaacgtt tcgccattac
     7201 tttcaatcac ttctttatac caataaaatg attttttctt atagcgattt atagtcaatt
     7261 gaaacaagag caggacaaaa gagcctcata aaaggtatt
//
LOCUS       DAVLUM010000086         6954 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLUM010000086 DAVLUM010000000
VERSION     DAVLUM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.086"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..1659
                     /gene="phtD"
                     /locus_tag="VYN42_001839"
     CDS             <1..1659
                     /gene="phtD"
                     /locus_tag="VYN42_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1462873.1"
                     /translation="DPAQITSRTARGVAVPHGNHYHFIPYEQMSELEERIARIIPLRY
                     RSNHWVPDSRPEQPSPQPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENG
                     VSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLPSSDREFYNKAYDLLARIH
                     QDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHPERLGKPNAQIT
                     YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERA
                     AAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVK
                     NGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFG
                     NASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGL
                     NPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIR
                     QNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
     gene            1869..4988
                     /gene="phtE"
                     /locus_tag="VYN42_001840"
     CDS             1869..4988
                     /gene="phtE"
                     /locus_tag="VYN42_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1462874.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     GRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            5161..6078
                     /gene="adcAII"
                     /locus_tag="VYN42_001841"
     CDS             5161..6078
                     /gene="adcAII"
                     /locus_tag="VYN42_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1462875.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            6086..>6954
                     /gene="phtD"
                     /locus_tag="VYN42_001842"
     CDS             6086..>6954
                     /gene="phtD"
                     /locus_tag="VYN42_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1462876.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHV"
BASE COUNT         2478 a         1232 c         1413 g         1831 t
ORIGIN      
        1 gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag ctgtccctca tggtaaccat
       61 taccacttta tcccttatga acaaatgtct gaattggaag aacgaattgc tcgtattatt
      121 ccccttcgtt atcgttcaaa ccattgggta ccagattcaa gaccagaaca accaagtcca
      181 caacctagtc caagtccgca acctgcacca aatcctcaac cagctccaag caatccaatt
      241 gatgagaaat tggtcaaaga agctgttcga aaagtaggcg atggttatgt ctttgaggag
      301 aatggagttt ctcgttatat cccagccaag gatctttcag cagaaacagc agcaggcatt
      361 gatagcaaac tggccaagca ggaaagttta tctcataagc taggaactaa gaaaactgac
      421 ctcccatcta gtgatcgaga attttacaat aaggcttatg acttactagc aagaattcac
      481 caagatttac ttgataataa aggtcgacaa gttgattttg aggctttgga taacctgttg
      541 gaacgactca aggatgtctc aagtgataaa gtcaagttag tggaagatat tcttgccttc
      601 ttagctccga ttcgtcatcc agaacgttta ggaaaaccaa atgcgcaaat tacctacact
      661 gatgatgaga ttcaagtagc caagttggca ggcaagtaca caacagaaga cggttatatc
      721 tttgatcctc gtgatataac cagtgatgag ggggatgcct atgtaactcc acatatgacc
      781 catagccact ggattaaaaa agatagtttg tctgaagctg agagagcggc agcccaggct
      841 tatgctaaag agaaaggttt gacccctcct tcgacagacc atcaggattc aggaaatact
      901 gaggcaaaag gagcagaagc tatctacaac cgcgtgaaag cagctaagaa ggtgccactt
      961 gatcgtatgc cttacaatct tcaatatact gtagaagtca aaaacggtag tttaatcata
     1021 cctcattatg accattacca taacatcaaa tttgagtggt ttgacgaagg cctttatgag
     1081 gcacctaagg ggtatactct tgaggatctt ttggcgactg tcaagtacta tgtcgaacat
     1141 ccaaacgaac gtccgcattc agataatggt tttggtaacg ctagcgacca tgttcaaaga
     1201 aacaaaaatg gtcaagctga taccaatcaa acggaaaaac caaacgagga gaaacctcag
     1261 acagaaaaac ctgaggaaga taaggaacat gatgaagtaa gtgagccaac tcaccctgaa
     1321 tctgatgaaa aagagaatca cgctggttta aatccttcag cagataatct ttataaacca
     1381 agcactgata cggaagagac agaggaagaa gctgaagata ctacagatga ggctgaaatt
     1441 cctcaagtag agcattctgt tattaacgct aagatagcag aggcggaggc cttgctagaa
     1501 aaagtaacag attctagtat tagacaaaat gctgtggaga cattgactgg tctaaaaagt
     1561 agtcttcttc tcggaacgaa agataataac actatttcag cagaagtaga tagtctcttg
     1621 gctttgttaa aagaaagtca accgactcct atacagtagt aaaatgaatg gagcatattt
     1681 tatggagaag taacctttcg tgttacttct cttttttaga aaaacgtaac agaaacttga
     1741 caaaagtaat tttaaatagt aaactattta ctggttaatt aaatggttaa ataaccggtt
     1801 tagaaaacta tttaataaag taaaagaagt tgagaaaaaa cttcatcatt tattgaaatg
     1861 agggatttat gaaattcagt aaaaaatata tagcagctgg atcagctgtt atcgtatcct
     1921 tgagtctatg tgcctatgca ctaaaccagc atcgttcgca ggaaaataag gacaataatc
     1981 gtgtctctta tgtagatggc agccagtcaa gtcagaaaag tgaaaacttg acaccagacc
     2041 aggttagcca gaaagaagga attcaggccg agcaaattgt aatcaaaatt acagatcagg
     2101 gctatgtaac gtcacacggt gaccactatc attactataa tgggaaagtt ccttatgatg
     2161 ccctctttag tgaagaactc ttgatgaagg atccaaacta tcaacttaaa gacgctgata
     2221 ttgtcaatga agtcaagggt ggttatatca tcaaggtcga tggaaaatat tatgtctacc
     2281 tgaaagatgc agctcatgct gataatgttc gaactaaaga tgaaatcaat cgtcaaaaac
     2341 aagaacatgt caaagataat gagaaggtta actctaatgt tgctgtagca aggtctcagg
     2401 gacgatatac gacaaatgat ggttatgtct ttaatccagc tgatattatc gaagatacgg
     2461 gtaatgctta tatcgttcct catggaggtc actatcacta cattcccaaa agcgatttat
     2521 ctgctagtga attagcagca gctaaagcac atctggctgg aaaaaatatg caaccgagtc
     2581 agttaagcta ttcttcaaca gctagtgaca ataacacgca atctgtagca aaaggatcaa
     2641 ctagcaagcc agcaaataaa tctgaaaatc tccagagtct tttgaaggaa ctctatgatt
     2701 cacctagcgc ccaacgttac agtgaatcag atggcctggt ctttgaccct gctaagatta
     2761 tcagtcgtac accaaatgga gttgcgattc cgcatggcga ccattaccac tttattcctt
     2821 acagcaagct ttctgcctta gaagaaaaga ttgccagaat ggtgcctatc agtggaactg
     2881 gttctacagt ttctacaaat gcaaaaccta atgaagtagt gtctagtcta ggcagtcttt
     2941 caagcaatcc ttcttcttta acgacaagta aggagctctc ttcagcatct gatggttata
     3001 tttttaatcc aaaagatatc gttgaagaaa cggctacagc ttatattgta agacatggtg
     3061 atcatttcca ttacattcca aaatcaaatc aaattgggca accgactctt ccaaacaata
     3121 gtctagcaac accttctcca tctcttccaa tcaatccagg aacttcacat gagaaacatg
     3181 aagaagatgg atacggattt gatgctaatc gtattatcgc tgaagatgaa tcaggttttg
     3241 tcatgagtca cggagaccac aatcattatt tcttcaagaa ggacttgaca gaagagcaaa
     3301 ttaaggctgc gcaaaaacat ttagaggaag ttaaaactag tcataatgga ttagattctt
     3361 tgtcatctca tgaacaggat tatccaagta atgccaaaga aatgaaagat ttagataaaa
     3421 aaatcgaaga aaaaattgct ggcattatga aacaatatgg tgtcaaacgt gaaagtattg
     3481 tcgtgaataa agaaaaaaat gcgattattt atccgcatgg agatcaccat catgcagatc
     3541 cgattgatga acataaaccg gttggaattg gtcattctca cagtaactat gaactgttta
     3601 aacccgaaga aggagttgct aaaaaagaag ggaataaagt ttatactgga gaagaattaa
     3661 cgaatgttgt taatttgtta aaaaatagta cgtttaataa tcaaaacttt actctagcca
     3721 atggtcaaaa acgcgtttct tttagttttc cgcctgaatt ggagaaaaaa ttaggtatca
     3781 atatgctagt aaaattaata acaccagatg gaaaagtatt ggagaaagta tctggtaaag
     3841 tatttggaga aggagtaggg aatattgcaa actttgaatt agatcaacct tatttaccag
     3901 gacaaacatt taagtatact atcgcttcaa aagattatcc agaagtaagt tatgatggta
     3961 catttacagt tccaacctct ttagcttaca aaatggccag tcaaacgatt ttctatcctt
     4021 tccatgcagg ggatacttat ttaagagtga accctcaatt tgcagtgcct aaaggaactg
     4081 atgctttagg cagagtgttt gatgaatttc atggaaatgc ttatttagaa aataactata
     4141 aagttggtga aatcaaatta ccgattccga aattaaacca aggaacaacc agaacggccg
     4201 gaaataaaat tcctgtaacc ttcatggcaa atgcttattt ggacaatcaa tcgacttata
     4261 ttgtggaagt acctatcttg gaaaaagaaa atcaaactga taaaccaagt attctaccac
     4321 aatttaaaag gaataaagca caagaaaact caaaacttga tgaaaaggta gaagaaccaa
     4381 agactagtga gaaggtagaa aaagaaaaac tttctgaaac tgggaatagt actagtaatt
     4441 caacgttaga agaagttcct acagtggatc ctgtacaaga aaaagtagca aaatttgctg
     4501 aaagttatgg gatgaagcta gaaaatgtct tgtttaatat ggacggaaca attgaattat
     4561 atttaccatc gggagaagtc attaaaaaga atatggcaga ttttacagga gaagcacctc
     4621 aaggaaatgg tgaaaataaa ccatctgaaa atggaaaagt atctactgga acagttgaga
     4681 accaaccaac agaaaataaa ccagcagatt ctttaccaga ggcaccaaac gaaaaacctg
     4741 taaaaccaga aaactcaacg gataatggaa tgttgaatcc agaagggaat gtggggagtg
     4801 accctatgtt agatccagca ttagaggaag ctccagcagt agatcctgta caagaaaaat
     4861 tagaaaaatt tacagctagt tacggattag gcttagatag tgttatattc aatatggatg
     4921 gaacgattga attaagattg ccaagtggag aagtgataaa aaagaattta tctgatctca
     4981 tagcgtaagg aatagcagta gaaaaagtct gaatcaaaaa tgaagttctc tcaaaagtta
     5041 gaaataaaac tctgactttg ggagaatttc attttattat taatatataa aatttcttga
     5101 catacaactt aaaaagaggt ggaatattta ctagttaatt aaatggttaa ggagttgttc
     5161 atgaagaaac aaaatttatt tttagtcctg ttaagtgtct ttcttttgtg cttgggggct
     5221 tgtggtcaaa aggaaagtca gacaggaaag gggatgaaaa ttgtgaccag tttttatcct
     5281 atctacgcta tggttaagga agtatctggt gacttgaatg atgttcggat gattcagtca
     5341 agtagtggga ttcactcctt tgaaccttcg gcaaatgata tcgcagccat ctatgatgca
     5401 gatgtctttg tttaccattc tcatacactc gaatcttggg caggaagtct ggatccaaat
     5461 ctaaaaaaat ccaaagtgaa ggtcttagag gcttctgagg gaatgacctt ggaacgtgtc
     5521 cctggactag aggatgtgga agcaggggat ggagttgatg aaaaaacgct ctatgaccct
     5581 cacacatggc tagatcctga aaaagctgga gaagaagccc aaattatcgc tgataaactt
     5641 tcagaggtgg atagtgagca taaagagact tatcaaaaaa atgcgcaagc ctttatcaaa
     5701 aaagctcagg aattgactaa gaaattccaa ccaaaatttg aaaaagcgac tcagaaaaca
     5761 tttgtaacac aacatacagc cttttcttat ctagcgaaga gatttgggct taatcaactt
     5821 ggtattgcag gtatctctcc tgaacaagaa ccaagtccac gacaactaac agaaattcag
     5881 gaatttgtta agacctataa ggttaaaacg atttttacag aaagtaacgc ttcttcaaaa
     5941 gtagctgaaa ctcttgtcaa atcaacaggt gtgggtctta aaactctgaa tcctttagag
     6001 tcagacccac aaaatgacaa gacctattta gaaaatcttg aagaaaatat gagtattcta
     6061 gcagaagaat taaagtgagg aaagaatgaa aatcaataaa aaatatctag caggttcagt
     6121 ggcagtcctt gccctaagtg tttgttccta tgaacttggt cgtcaccaag ctggtcaggt
     6181 taagaaagag tctaatcgag tttcttatat agatggtgat caggctggtc aaaaggcaga
     6241 aaatttgaca ccagatgaag tcagtaagag agaggggatc aacgccgaac aaattgttat
     6301 caagattacg gatcaaggtt atgtgacctc tcatggagac cattatcatt actataatgg
     6361 caaggttcct tatgatgcca tcatcagtga agaacttctc atgaaagatc cgaattatca
     6421 gttgaaggat tcagacattg tcaatgaaat caagggtggc tatgtgatta aggtagacgg
     6481 aaaatactat gtttacctta aagatgcggc ccatgcggac aatattcgga caaaagaaga
     6541 gattaaacgt cagaagcagg aacgcagtca taatcataac tcaagagcag ataatgctgt
     6601 tgctgcagcc agagcccaag gacgttatac aacggatgat gggtatatct tcaatgcttc
     6661 tgatatcatt gaagatactg gtgatgctta tatcgttcct cacggcgacc attaccatta
     6721 cattcctaag agtgatttgt ctgccagtga attagctgct gcccaagcct attggaatgg
     6781 gaagcaggga tctcgtcctt cttcaagttc tagttataat gcaaatccag ctcaaccaag
     6841 attgtcagag aaccacaatc tgactgtcac tccaacttat catcaaaatc aaggggaaaa
     6901 catttcaagc cttttacgtg aattgtatgc taaaccctta tcagaacgcc atgt
//
LOCUS       DAVLUM010000087         6914 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLUM010000087 DAVLUM010000000
VERSION     DAVLUM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.087"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            62..991
                     /locus_tag="VYN42_001843"
     CDS             62..991
                     /locus_tag="VYN42_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1462877.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            1005..2444
                     /locus_tag="VYN42_001844"
     CDS             1005..2444
                     /locus_tag="VYN42_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462878.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            2513..4090
                     /locus_tag="VYN42_001845"
     CDS             2513..4090
                     /locus_tag="VYN42_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1462879.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            4150..5610
                     /locus_tag="VYN42_001846"
     CDS             4150..5610
                     /locus_tag="VYN42_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1462880.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNIEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            5632..6087
                     /locus_tag="VYN42_001847"
     CDS             5632..6087
                     /locus_tag="VYN42_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEV1462881.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            6174..6580
                     /gene="cdd"
                     /locus_tag="VYN42_001848"
                     /pseudo
     CDS             6174..6580
                     /gene="cdd"
                     /locus_tag="VYN42_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            6593..>6914
                     /locus_tag="VYN42_001849"
     CDS             6593..>6914
                     /locus_tag="VYN42_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1462882.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGT"
BASE COUNT         2434 a          896 c         1297 g         2287 t
ORIGIN      
        1 ttattagcta ataagattgc taaaaaactt ggcgaagaag gaattgtata aggggggtaa
       61 aatgattttt tcaaaaaata caaaaaagag taatagagac aaagaaacct tcgttgatta
      121 tctctttata ttcattttaa taataataac cttacttatg ttgtatccat tatggtgggt
      181 agtgatgacg tcactttcag aaccagtttg gctatctaaa aacgttgtta aattatttcc
      241 cttaaaaata gatattactg catataagtt tatttttggg gattctaaac tatggcaagc
      301 atatggtaat agtgtattgt atgctgcact atctacaatt gttagtgttg cggtatgtag
      361 tatgtatgcc tatccactta caattcctga aattaggggt aaaaaattct ggaatactct
      421 tattttgatt ccaatgttct ttagtggagg aatgatcccg ctttatatac aagttgcaaa
      481 cctcggttta ttgaatactg cttgggctct tgttttacct ggtgctgttt ctacatatta
      541 tataattttg tttagaacac agtttaaatc aatcccaatg gagcttcgtg agtctgctag
      601 aattgatggg gcaagtgaat ttagaatttt ttggaattta gtattaccat tatcaaaagt
      661 tattttcatg attatagcac tttattgcat agttggttca tggaatagtt ttactcctcc
      721 attactttat ttgaatgacg acactaagat gcctttatct atttatttga gaaatttagt
      781 tgttacaaat acaactgata ctgctgaatt atcactttct gcaggtaata catattacca
      841 acaaattgct gctcaaggtg gaggtattgg tatgcgtatt gctattaaga tgggtactat
      901 tgttgttagt gttattccaa ttatgatgat ttatccattt attcagaaac attttgttaa
      961 gggaatcctg ctaggttctg tgaaaggtta ataaggtaat tattttgcaa aatttaaaaa
     1021 aatatctttt attagatagc ggtttagtag ttgggtatac attagaaaat gctcaattaa
     1081 aattaaataa gctaaaaaaa gatactgaaa acaatccact atttggtgaa gagtattttg
     1141 ccgaaaatcc taaattatgg gaagttcgtt ttgataattc atatccaaac gttatctatg
     1201 ataaagaatt gaaattatat agatgttggt atcaaacatt tgttagtgat gaagcaagcg
     1261 aagagactcc tttagcagaa cgtggagaga aggaatacat tgtcaagtca tctagaatga
     1321 cagcactttg ctatgctgaa agtaaagatg gagtaaaatg ggaaaaacca aatctcaatc
     1381 tagtaaaatt taaaggttca aaagataata atattgttct gatgcatgca cacggtgcag
     1441 gtatcatgct agatgaacag gagttggatc ctaagaaacg atataaatta gtttcaaaat
     1501 tagaattttc tccgaatctt cattacatgg ttgttgtttt ttcagaagac ggtattcatt
     1561 ttgacgaacc tattccatgg aaaaaatgga atcctgcagc agatagtcat aattttccat
     1621 ttagagatcc aaaaactggt aaatacgctg ttattacaag aacctgggca aataacgtac
     1681 gtctaagtgc aattactttc agtgatgatt ttattaattg gtcagaacct aaagaaatcc
     1741 ttaggggaga tggatttgaa gatcaaattt attctatgcc agtaatttca tacgcggata
     1801 tctatttagg ttttgcttca atgtaccacg aaggcgacac tttaaatgaa aactatgata
     1861 aagtagactt agaattgaaa ttctctgcta atttggaaca atgggatagt gtatgtaagg
     1921 gcgactatct cattgaaagg ggaggtggag tatacccgca gaatgctgat tttgatgcta
     1981 gttgtatttt cacggctgct ccaataattg aagatgataa gatttggttc tactatatgg
     2041 gtggaaatgg taatcacact ggcttccgag aaagttcatt agctagagga tatattaaga
     2101 aagaccaatt tgcttattat actaataaga gagaaggaat tccagctaaa atatctacag
     2161 ttagcttcca aacttacgat gatgaaattt atatcttagc tgatattcct gaaaatggtt
     2221 atattaaagt tgcggtaggt actaaatacg gtaatgctta ttcagatttt ggtcaggaag
     2281 atatctctct tgttcaagtt tccgatggta agtataagtt ggaatttaat aaaaaatcta
     2341 tcttagattt aggtaattct ccagttgcgt tcaaatttga aatcgagaat gcaaaattgt
     2401 atggtattga aggtagtatt cagcaacact atctcaaata ttaaccagaa taattcgtta
     2461 acaaataatc tctatattag tggagataga tatataaaat ggaggtctta ttatggtaaa
     2521 gcttaataag gtattaaaag ggagtgttgc attcctgagt gcaagtttat tgctagcagc
     2581 ttgtggcaat aacgctaatt caaagcccgc tgaaaaaaca gctgatggta aaacgaaaat
     2641 ttcgtttcta tctacatggc aaattaatga tgttcgtccg cctaaagatg aaacacttgt
     2701 tggtcaatgg ttagaagaac agctaggtat tgatattgat cttgtaacta ttcctggcga
     2761 gggagtaagt tctaaagtaa attctcttat tactagtaac cagttaccga ctgttttgtt
     2821 gacaacagga gataagagtg atatcgctgg tatcaacaaa cttggtaaac agggtgcatt
     2881 cttagatttg tcacaacaca tggacaaact accaaactat aagaagtacc ttgaaaaaaa
     2941 taatgcatta gctcaaatag aagatgatga aaaacatatt tatgctttca caaaattctt
     3001 tactgatgag aatatcatgt atactacacc aattctgaga aaagacttac ttgttggttc
     3061 agaatttgaa gatctttcaa aaattaaaac tgttgatgac tatacaaaag ttttgaaata
     3121 tttgactgaa aaacaaggtt ctccagcatt tattcaacgt aatggctatg aaggcttcat
     3181 gaagcgagtt acaccattgt ggaatttaag ccatcgtaca tactatgact atgaatcaga
     3241 ttcatataaa catccagttg aacaacctca attgaaacaa ttcgttgaat ggttgaaaga
     3301 attacgtaaa gataacgtac ttcaccctga ctgggcagtt atgaaagatg aaacttggga
     3361 aggtctattg gcttctaaca agggttcatt cactgttgac cgtatgaata tcattggaga
     3421 taataacttt gataaatcat ttgattggca gccacttgtt tatccaaaaa ttaatggaaa
     3481 acgttatttg caaccgaaaa caccgtacat ttctgattca ggttgggtaa tcaatgccaa
     3541 tgcaccaaaa gaagaaattg ataaagcgtt agaattcttt aatttcttat acgctgatga
     3601 aaatcaagaa aaacttgcta ttggatttga aggtaaaaca tttacacgtg aaaaccctaa
     3661 tactcaagca ggtattaaat ggttgattca aatttacggt gaaaatgctg gaaatgataa
     3721 agcagaactg ctgtttaaac atggtaacca agcatttact cgcgttcaaa ctaaattaga
     3781 tattgaggca cagccaggaa cattccctaa agttatgtat gatcaagtag ataaaattaa
     3841 gaaagattta ggtggtttta gaccagatac tccggttctt tcctttacaa ctgaagaatt
     3901 agatgtttta actaaatctg aagcaggatt aaatactttc tttgatgaaa atattattaa
     3961 attcattgaa ggacaaagag atatgagtga gtgggattca tttatcaatg aagctaaatc
     4021 taaagacttg gataaagtta caaaagtata taatgatgcc tacaaacgtg tcaaagatag
     4081 aatgaaatag actaaatggt agctctctgg tttttcagag agctactact gcctgagggg
     4141 gagtaagctt tgtatgatgt agtaattata ggtgcaggaa gttcgggcgc attggctgca
     4201 attgcttcgg ggcgtctagg gttaaaaact tgtctaatag agaagggaag tagaattggt
     4261 ggagttccta ttaatacact aatggggtca tttgctaatc tatattttga tgattctggt
     4321 agagtaaatg caagtaaaat tgttggggaa ttaatagaac gtattatcaa aaaaggtggt
     4381 actgtcttta actctatgga agaattgatg aatgtaaatg atttttatca gattacaatt
     4441 ccctatcaac cagaagttta tgaatcggtt ttaactgata tgttgattga gtctaaagtt
     4501 gatattttac taaatattga agttaataat attatttatg atagtaaaaa tattaaaagt
     4561 cttgaaattt taagtaatca ggaagttaaa ttgattgatt ctaaagtttt tattgatgct
     4621 acagggaatg caacaattgc ttctgctagt ggagctgatg tttatgaaaa aaattcttct
     4681 tacggttgtt taatgagagt tggaggagtt gatatctcaa agactataga acatattgaa
     4741 aaaacaaagc agtggaacta tatagaagga tataatcagt ggttagaaga agtattagca
     4801 aatcgaaagt acagagccac tggagcagtt ttaaaagatc cagtttctta tgatcatgcc
     4861 cctatgcttt caaaagacga ccattttatg aatgatgaaa aatggaatta cattaaagaa
     4921 agatgggaaa aatttagatt tatttacact ttagaagtat cactatttag gaatgaatta
     4981 aaaaaagctg tagaatctgg ggattttaat tttgaaattt atcatgatga taaatctgga
     5041 gtcactatga atggcgacgg tataagctat ggttcatggg gtcaaaatgt agcattaatt
     5101 aatgttgcaa aagcatttgg attcaatccc aaatatatgg aagatgaatc acatgctaat
     5161 attctttcta gaaaatataa tttaacattt ttatcttttc ttaaaaaata tgtaccaggt
     5221 tttgaaaatt cttttatcct tgatcaggga actagagcta ctaacagatc atgtaggcac
     5281 attgataatt catctatgat ggacgaaatt cttgattttc caatgtatac atttaagact
     5341 atgtatagct atcaaactcc taaagaaata acgtacaaat caattgtagg tggaaaattg
     5401 aataatttgt ttgtaatagg taaaggtgct taccaatccg aaagttttag atcacaaatt
     5461 agttgtatgt taatggggat atcatcagca gcagcggcaa aaactattat tgaagataaa
     5521 agcaatactc taaacattaa tagagatttg tttaaatcga acttagatat attatttaca
     5581 tgggagtttt ctaattggat tactgattaa caaataataa gggaatatta aatgaatgat
     5641 actaataaaa atcaatactt tgtttatgaa tttgatacta gctttgtaga aatgtcttat
     5701 tctcagtttt ttgaaggata ttgtattctt ttttcaaaag aaccctatcc ttctttatct
     5761 gatatgccaa tggaatttag aaaagaattt ttaatggaaa tgagtatatt aggtgatgcg
     5821 atgcttgaag tgttaaatgc ctatagaatt aattatgata tcttaggaaa ttcaacacct
     5881 gtacttcatg ctcatttatt tccgagatac atgtgggaag aggaagagag aagaaaaact
     5941 gtagttcata gatatgattc ttcagttttt agcaatcctg agtttgaatt tactatagaa
     6001 aagcatggac caattattaa aaaactgagg tctgctattg atagacatta tagagagtat
     6061 caacaattat tagatgattc aaactgaact ccacattttc gattagattt aataccttgt
     6121 atattacaac taggttgtgg atgatataat tttttgaaaa atatatttta ggaatgactt
     6181 ataaagcaat tatatcagag gctattaaat caatggccaa agcttatgct ccttattctg
     6241 attttaaggt tggagctgcg ttagtaactg aagataaaaa attttttctg gatgtaatat
     6301 agaaaatgct gctttttctc ctacttgctg tgcagaacga gtatcttttt ataaagctgt
     6361 atttaaagga gaacgttcgt tttcaagaat atgtattgta ggtggaaaaa atggtatctt
     6421 atcatctttt atagcacctt gcggagtgtg tcgccaggta atgatagaat tttgtaatcc
     6481 tgattcattt gaagttatat tggctagtga tgttgatact tataaagtat ataaacttaa
     6541 agaactacta ccagttagtt ttaatcaaga aaatttataa caggagggaa ctatggaatt
     6601 agttgaattt aaaaatggac atgttaatac ggttcatgag catatcgcaa taacgaaagt
     6661 aaaagagttt ctaaataatc atgatatacc aaaagataaa ggtggcatac ataaaatttc
     6721 tactgatttc ttttacaata taattgatat ggaaactaca actgaagaga atagaccgtg
     6781 ggaaagtcat aaggaatatt atgatgtcca ttatctgtta aatggagaag aaataatttt
     6841 atataatttc ttgtctcaaa tggaattgtc tgaatataaa gtagatgatg attggcaaca
     6901 aatgaatggg acag
//
LOCUS       DAVLUM010000088         6690 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLUM010000088 DAVLUM010000000
VERSION     DAVLUM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.088"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..2263
                     /locus_tag="VYN42_001850"
     CDS             <1..2263
                     /locus_tag="VYN42_001850"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1462883.1"
                     /translation="QYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTY
                     QDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDVFRKE
                     TGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLATFSNQ
                     DVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKA
                     LYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPR
                     GFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVKADWS
                     NGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGE
                     DFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAH
                     KVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSIDFRES
                     INALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQAIQN
                     QYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSSTNKG
                     LLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKGYLNL
                     QNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNTDYHL
                     TVDLAQSMLTLPC"
     gene            2280..2750
                     /locus_tag="VYN42_001851"
     CDS             2280..2750
                     /locus_tag="VYN42_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1462884.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(3254..6604)
                     /locus_tag="VYN42_001852"
     CDS             complement(3254..6604)
                     /locus_tag="VYN42_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1462885.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIENLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         2079 a         1457 c         1133 g         2021 t
ORIGIN      
        1 tcaatatagt tatatcaatt ttccaaaaga aaatgtctta tctgaactaa aaaaatgtgg
       61 ctttgattta caaaatacag ccaatcacaa agactcactt gaaacctttt tacgtcgttt
      121 ctttttcact tatcaagaca ccaactaccc actttcgatc ctagcagctg ataaaaaaac
      181 agacctgctg acattttttc aatcagaaga tgaactgaca gcagatattt tttatactgt
      241 tgcttttcaa cttttaggct tttcttattt ggttgacttc gaagatagtg acgtttttcg
      301 taaagaaact ggatttccca ttatatatgg tgacttgatt gaaaatctct atcagttact
      361 caatactcgc accaaaaaag gaaatactct tatcgaccaa cttgttagtg atggtcttat
      421 tccggaggat aatgactacc actactttaa cggcaagagt ttggctactt tttctaacca
      481 ggatgtcatt cgtgaagtcg tttacgttga gtctcgtgtc gatactgacc aaaaagggct
      541 atcagaccta gtaaaggtta gcattattcg ccctcgtttt gatggaaaaa tccctgccat
      601 catgacagcc agcccttatc atcagggaac caatgacaag gctagtgaca aggctctcta
      661 caagatggag ggcgagcttg aggttaagct tcctcacaag attgagctag agaaacctca
      721 actaaatctc gtccaacccc aaggtaaagc tgagcttata gcagaggctg aggaaaagct
      781 aactcacatc aactctagct atacactaaa cgactacttc cttccgagag gctttgccaa
      841 tctctatgtc tcaggtgttg gtaccaaaga ctcgacaggt ttcatgacta atggagacta
      901 ccagcaaatc gaggcttata aaaatgtcat cgattggctt aacggccgtt gccgtgcctt
      961 tactgatcac acgcgccagc gtcaagtcaa ggctgattgg tcaaacggaa aagttgctac
     1021 aacaggactt tcctatctag gtaccatgtc caatggtctt gcgactacag gagtcgatgg
     1081 tttagaagtt atcattgccg aggcaggaat ttcatcatgg tacaactact accgtgaaaa
     1141 cggtctggtg actagcccag gtggttatcc aggtgaggac tttgactccc ttgctgagtt
     1201 aacctattct cgtaatctct tagctggcga ctatatccgt ggcaatgaag ctcaccaagc
     1261 tgacttagaa aaagtgaaag ctcagctaga ccgaaaaact ggggactaca atcagttttg
     1321 gcatgaccgc aattatctgc tcaatgccca taaagtaaag gcagaggttg tctttactca
     1381 tggttctcag gattggaatg tcaaaccact tcatgtttac cagatgttcc atgctcttcc
     1441 tactcatata aacaagcatc tctttttcca taatggtgcc catgtttaca tgaacaattg
     1501 gcaatcaatt gacttccgtg agtccataaa tgccttattg accaagaaat tactaggaca
     1561 ggaaacagac tttcaacttc ctactgttat ctggcaggac aatacagctc cacagacttg
     1621 gttatcactt gataacttcg gtgggcaaga aaactgtgaa accttctcac ttggtcaaga
     1681 agagcaagct attcaaaacc agtacccaga taaggatttt gagcgctatg gtaagacata
     1741 ccaaaccttc aatacagagc tctatcaagg gaaagccaat cagattacta ttaaccttcc
     1801 tgtgactaaa gatctccacc taaacggtcg cgctcagctc aatcttcgta tcaaatccag
     1861 tacaaacaag gggctcttat ctgcccaact gctagaattt gggcaaaaga aatacctaca
     1921 accttatcca gctattttaa gtgctagaac cattgacaac ggtcgctatc acatgttgga
     1981 aaatctctgt gaattgccat ttagaccaga ggcacaacga gtcgtgacaa aaggttacct
     2041 taatttacaa aatagaaatg atttactgtt agtagaggat attactgcag atgaatggat
     2101 ggatgttcaa tttgaactgc agccaactat ttacaagcta aaagaaggag acactctccg
     2161 tttagtcctc tatactactg actttgaaat caccatccgt gacaatacag actaccactt
     2221 gactgtcgac ctcgctcagt ccatgcttac cttaccttgc taaaaggagt tacattatta
     2281 tgaataaatc agaacaccgc caccaactta tacgcgctct tatcacaaaa aacaagattc
     2341 atacacaggc tgagttgcaa gcccttcttg ctaagaacga cattcaagta acccaggcaa
     2401 ccctctcacg cgacatcaaa aatatgaacc tatcaaaagt ccgcgaagaa gatagcgctt
     2461 attatgttct taacaatggt tccatctcaa aatgggaaaa acgtctcgaa ctctacatgg
     2521 aagacgccct tgtctggatg cgcccagttc aacaccaagt cctactaaaa acccttcctg
     2581 gactggctca atcctttggt tctatcattg atactttgag cttccctgac gctatcgcta
     2641 ccctttgtgg taatgatgtc tgtcttatca tctgtgaaga tgcagatact gctcaaaagt
     2701 gctttgaaga actgaaaaaa ttcgccccac catttttctt tgaagaataa taaatgacta
     2761 caactaacaa ttatgcttaa aaaaactggt agaaagtctt taacatcaga aaacgcatag
     2821 tatcaagtgt tgaaaaccct tgatactatg cgttttgctt tatcctagga agatttatac
     2881 tcttcgaaaa tctcttcaat ccgcgtcagc ttccatctgc aacctcaaaa cagtgttttg
     2941 agcagcctgc agctagtttc ctagtttgct ctttgatttt cattgagtat tatttcattt
     3001 tctcctgcaa ttgaattctt gctcggcttt ttgttttcta tttctttaaa atcaaagtag
     3061 ctcttttgtt aataactcga tcaacaaaca tcgtggtaca agtatctact ttgaaattta
     3121 tcaaccactt aacaactgat actgtattct aggaaaacga tgacattctt cctaataaaa
     3181 cttctcatat atagcataaa tttctactct ttttaatttt aaatgagtct cagcatggca
     3241 atcactttag aatttaagcc gcttctccag ctcgattatt gataagttca atgatttgaa
     3301 caatattacg aagtactggt agttggtgtt ggaagagtag ttgaacagaa ccataagatt
     3361 taaacggctc ttgcgttaac actttcgtct ctaaaaaacc attttctaca atgtagtcta
     3421 caatcaattt tacaaatgaa atctgcctgg cattaagatt ctcatccgac aaaaatttag
     3481 aaaaaatacg attggcagac tctctatcta agccaataat ctcacgaacc aatctcggaa
     3541 ttgccttatt ttcataatga ctttggtagt ctgctttact acctaatttt tcccagagca
     3601 atttttcaag tgcaagcata tcatcagatg tcaacttttt attatggtat agcttagaaa
     3661 tggactcctc atccagatga gttttcaaat aatgctcaac tttttcattg taagaccgaa
     3721 gatcgttgac ctgcaaaaat gctgtggtct cgtgaacagt ggagagtata cgatcttcaa
     3781 agttaacata gtagggttta cggtctgttt tatccaaaaa ctgtaataaa tctcgaatag
     3841 caagacgaat tttttccaaa tcagacaagt taacttcttt ccaaaattca ggctcctgta
     3901 ctttcctgat aatttcagcc tgctcaaaaa cctgcgggat attgccaata gcagaaagag
     3961 ctctagccgt cttcatcact tgggaaatat gaacagtgga agatttagct gtcagttgcc
     4021 ccaactgaat atgaagcaac cacaaatcaa atctcctcgc catctcatct tctttatctt
     4081 catcaaataa aagcggagag agattttttt gaatggtttc acttgtaaca gcagttagat
     4141 tctgccaact ttccaatttc ctatagctat aaactgtatc taaaaccata cgaaccctga
     4201 agtccaactc atttaagttc tctatacgac cttgaagttc cgagacaagc tgctgacggt
     4261 atgctctcgc aaactgatct tcttggtatt ggagtccctg aagttctcga atcaagtcca
     4321 ctttgatatt aaataaacgc tgagtcaacg aaacaatgtg acgaccctct ccatctcttg
     4381 gatctgcacg aaaataatca aaattatccc cataatcaaa taccaagaag ttttccttat
     4441 cctgctcagg tccaaataaa tctttacata gacgggttcc tcgaccaatc atctgccaaa
     4501 acttagtttt agagcgtact ttcttgaaga agactaaatt aacaacctct ggtacatcaa
     4561 tacctgtatc taacatatcg acagaaatcg caatttgagg atacttctcc ttaattttaa
     4621 aatcatcaat caaggtctga taatgcttaa tactataatc aatcacctga gcatagtcgc
     4681 tccctttttc aggatagcgg ttgttaaaaa tacctctgat atattccgca tggtcatgat
     4741 ttttagcaaa aataatagtt ttaccaattt catcacccga ggctgtctga attcctcttg
     4801 tcatgagttc atttaaaaca atttctactg tacttttatt gaaaataaag gaattaaaca
     4861 cactcccatc aatatctttt tcacagctat cgtcttcaaa tttgctatca aaatgttcct
     4921 tttcttcttc ggacaaatca tcataatgta gaccatccgt aggtagtttc agtttggttt
     4981 cgatagaatg ataggctact aaatatccgt ctttaacagc ctcttccaaa tcatatgcat
     5041 atgttggaac cccattctcc aaattaaaga atccataggt gtttttatct aaatcttgac
     5101 gcggagtagc tgttaagcct acaattcttg catcaaaata atcaaaaatg gacttgtatt
     5161 tctgataaat agaacggtga gattcgtcaa ttatgataag gtcaaaatgc ccaacagtaa
     5221 aagggcgttg atttacttct tcttgaccac taatcgctcc aatcatggtc ggataagttg
     5281 aaaagaccat acgacttgat tgagctcctt ctttatcttc taagaagtta caaacggaaa
     5341 gatctgggag taattttcta aacgaatcat aggcttgctt aaccaaggaa gttctatcgg
     5401 ctaagaagag aacgtttttt acccagttat gacgtgataa gatatcaact agagaaactg
     5461 ctgtacgagt tttccccgcc ccagttgcca taaccaaaag tgcctgtcta cgatgattag
     5521 agaaagcttc acaaacgctt gcaatggcat gtttttggta gtgacgcccg gaaatatcgt
     5581 ccctaatttt actagaaata tcctcaagcg gtttttgaag atgacgtcta tccatcacta
     5641 attgcaattc ttcttgagag taaaagcctg caatctggcg gcggttcgga ccatcaagta
     5701 tatagtgctt caacccattt gtaataaagc aaattggctg atagccgata tgtttctcca
     5761 aagcttcagc atattctttg acctgtactt cccctacttc tggattgaca gaggcttttt
     5821 tagcctccac aatcgctaaa attttcccat ttttaccata aagtacgtag tcacagtaac
     5881 caattcctga accgtgcttg agaccatcaa cggctatctc aacacgacag ttttcttcaa
     5941 atatccatcc tgctaaacgg agatcgatat caataaagag ctttcttgtc tctgcctcag
     6001 ataattgttc aatatggaaa ggcacatctt gccgttgcgc tgcagtctca cgtttttcag
     6061 tataagtctc ttgaacttct acggactgag cagccatctg ttcatgaaaa tcaggcagtt
     6121 ctggtaaact gtcttgtaac tttatcatag attgtggagt ttctcggtat ttgatgtttg
     6181 ctgaaagtgg taagcacttc tcatcaaaat aacgctccac aaattcattg ctgtaacaat
     6241 aatcgataaa attaacaaac tgatacaaat gatgtaaagc taaaatcgct tctcgttcct
     6301 taatttcacc accatgagca gcatggtttc cccaccgaat caacagaact atctgcttgt
     6361 ggagttcaga atctacgata tccctaaaat catcatccca tactaaagaa gatagagtag
     6421 cacgataggg agcttctaaa tatgaatcgt gactatatat ccaatggaca gcctgctcca
     6481 aagcacgacg cgccataaag gcagtagcca cagttgatgt agcaatcata ttttcagctt
     6541 caatgcaagg ttttgaaaaa gattcatatt cgtcattttt taaaagaaag ctaaaatttc
     6601 ccattttttt ctcactttaa acaaatagtt tagctatatt atactaaatt tcaagctatt
     6661 tctccacact tttatagcta tctcacaagc
//
LOCUS       DAVLUM010000089         6180 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLUM010000089 DAVLUM010000000
VERSION     DAVLUM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.089"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..1217)
                     /gene="ltrA"
                     /locus_tag="VYN42_001853"
     CDS             complement(<1..1217)
                     /gene="ltrA"
                     /locus_tag="VYN42_001853"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV1462886.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIALTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLE"
     gene            complement(1970..2648)
                     /locus_tag="VYN42_001854"
                     /pseudo
     CDS             complement(1970..2648)
                     /locus_tag="VYN42_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(2716..4539)
                     /locus_tag="VYN42_001855"
     CDS             complement(2716..4539)
                     /locus_tag="VYN42_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1462887.1"
                     /translation="MVITKHFAVHGKCYRKKIIKYILNPEKTENLALVSHYGMRNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRHEENQRLIHAHHIIQSFSPEDHLTPKQINQ
                     IGYETMKELTGGKFRFIVATHVDKNHFHNHIIVNSVDNNSDKKLKWNYKVERNLRMIS
                     DRFSKIAGAKIIENRYSYHQYKVYRKTNHKYELKQRLYFLMENSTDFEDFKKNAPLLH
                     VKMDFSHKHATFFMTDSTMRQVVRGNKLNHKQAYTEEFFKNYFAKRKMEELMEFILPK
                     VDNLEDLIKKAKLFGLNINPKQKHVSFQFAGVEVKETELDKKNLYDVEFFKDYFEKRK
                     DLKAPEVQDLVQVYQEERFSKEKELPSEEKFWESYQEFRRNRDAIHEFEVELSLNQIE
                     KVVDDGIYIKVKFGIRQEGLIFLPNMELDMEEDKVKVFIRETSSYYVYYKDDAEKNCY
                     MKGRTLIRQFSSENQTIPFRRKTTVEMIKEKIEEVYTLLELDTDKHSYITIKDELVHE
                     LAASELRINAFQERVTTLNQVAEYLLASVENKQEMKMNLSKLNITDKIGIDVVEKELN
                     ELGIQIELESDRYENIVFKLNKFINRLSKKISKEEGIGFQK"
     gene            complement(4526..4891)
                     /locus_tag="VYN42_001856"
     CDS             complement(4526..4891)
                     /locus_tag="VYN42_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1462888.1"
                     /translation="MENRYRTNLKKVFLSDSELGQLKHCIDQSGCQSFSEYARRTLLD
                     PGMNFITIDTTGYQDLVFELKRIGNNINQIARSVNQSQLISSEELQDLKKGIADLIRE
                     VEKEFSIQAKKLREFHGHH"
     gene            complement(4896..5252)
                     /locus_tag="VYN42_001857"
     CDS             complement(4896..5252)
                     /locus_tag="VYN42_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462889.1"
                     /translation="MPEQYRDIRKEVNLTANELEMIGVMMKNKGFEHFSSFARNKLLE
                     NELEMTAEKWFTFWRAQKLEQISRDVYEILILSRAEHQVTQEHVSILLTCVQELIQEI
                     GNSISLSQDFRKKYMR"
BASE COUNT         1792 a         1301 c          930 g         2157 t
ORIGIN      
        1 ttttcaagga ctggttttga tatagcacgt ttaagtaccg acttctgagc tactaattga
       61 taatggtcgc cccagccaga taccttatct gctatccatt taggaactcc taacttaagc
      121 aatccccata atcgtctcga tttcttcttc cattgcttcc agataatcac tcgtaggcga
      181 gtacgcaagc gctcatctat gctggcgact atacttttca tatttcccaa tgagaaatag
      241 tttatccatc ctcgaataga caaattcagt tgctcaatac gtcttgttag agctatactc
      301 catttcctct gtgttagttt cttcaattta agcttaaatc tccgaacact atcttgatgt
      361 ggacggcttt tccaaccatc tgatgatttc cagaacccaa aacctagata tttcaactct
      421 cttggtctgg taatcttagt cttggtcatg tttactttca aacctagccg tttctcaata
      481 aaacgactga ctgaatacat cacacgctta gcggctgcct cgcttccgac cgtaatcaca
      541 caatcatctg cgtagcgcac aaatcgaagt cccctctttt ctaattcctt gtccaattca
      601 ttaagcatga tattggataa gagaggagat aaatttcctc cctgtggtgt accaactagt
      661 gttttataac gttgaccatt aatgataaca cctgaatgaa gatacttacg aatcaaggat
      721 tccgtatctc cgtcttcgat aatgttatgt actaaggaca tcaatctatc ttgaggaact
      781 gtatcgaaaa atttctctag gtctatatcc actatccact catagccgtc atttaagtat
      841 tctaagagct tcatgatggc tttttcacat gacctatttg gtctgaagcc ataactcgta
      901 tctgagaaat ggggttcaca aatggggcta ataacttgga caatggcctg ttgaatcatt
      961 ctatccataa ctgttggaat tcctagttga cggatgcctc cgtctggttt aggtatctca
     1021 actttaagaa ctggttgagg cttatatttt ctctgtttta tcagttcctt agtcaagcgc
     1081 cagttttgtc tgagataatt atccatctct tcgatagtca ttccatcaat cccagctgag
     1141 cctttattgg attttacttg attgtaggct tccagcatat tttcgcgtga taatatctta
     1201 tctagcagtt ttgacatgtg cgtattcctt tcttgttttg gtgcctgagg gacatcttat
     1261 attggtgaac cttcatctag tcattacgtg tcaaagtcca gttctatcag accactcatt
     1321 ttacagacac aagtgaagta ggattacttc gatctgtcgt tttctctttc tagcgacaga
     1381 cctcaaacag tctctcccca gactgtttga gtattcaccc cttcgctcca cttccattac
     1441 ggaaatttcc tcactactat gggctcggct gacttctcat gattcgttgt tactacgctt
     1501 tcagcgctca tgaaacctca cgggataagt cgtacatctt tcctcgttta tacaagatat
     1561 gaggacgtta aaaggttaca gtgaaaatag gaaatctgac gcagagtctt tagactctag
     1621 aaagatttat ctttttcaca caaaccttag tccgaattca attactctcg tgatttacac
     1681 atataggtta cgactacctt tttggacttt agagtttgaa gcctccttat ccgctatata
     1741 cgccttacta tcacgttcct gttcgtagag ccacgatttc gctatccctt cctctccctg
     1801 ctacctcacg atagtcaggc ttgggaatcg ctattgggtt caccggtagc aggtgcccac
     1861 cgaggactta cacctcagat gcacgacatg cccgtcgtac cttaaaaagc cttggaaaaa
     1921 actgtttcca aggctttctc tatatttgtc cttattgacc aaaccagtta cattgcttta
     1981 tcgtatctgt gattttagta atagcctctt cagtattatt ctgcaaccat agatagcgac
     2041 aaacattata attaaattta atagaaaggt ttaattcttc gattgtgttt aacttgagtt
     2101 gatttacttg atactctaac ttttctctaa tttcattaaa actctctaaa tcttcaatat
     2161 cataataaaa attgaataga gtatttgcaa cttgagggta ggtcaagtca gttacactta
     2221 actgagatag taccttctcc aatattgcca cagcctcctc tttttgccca tagaaataaa
     2281 aatctataag agattttatc cactccatat aaaatttatt taccagagac aagcgatgta
     2341 cctttacact ctctaattca tatatatttc aaagattcat aatttcgatt tgtgataaat
     2401 gtctgggcta actttttaaa ctctgataac tcatcaatct cttctacaat ctgctcatta
     2461 aaaaaataat ctacactaac ttttaacttc ttagacagag catataaaaa gtctgctcct
     2521 ggagtaaatt ctccattctc taatcgacta atctgtccct gtttacatat cccctcagtc
     2581 aattctcgct gagacatttt taattctttt cgtctatttt ttaatctggt tgctaatagt
     2641 gtgcccaagt ttgcattttc cttttctatt cgatttcaaa agatacaaat tatatataag
     2701 caatgactag ataggttatt tttgaaaacc tatcccttct tcttttgaaa ttttcttact
     2761 caaacgattg ataaacttat tcaatttaaa tacgatgttc tcatatctat cgctctctaa
     2821 ttctatttgg atacctaact cattcaactc cttctcaaca acatcaatgc caattttatc
     2881 agttatattc aactttgaaa gattcatttt catttcttgc ttattttcaa ctgaagccag
     2941 taaatattct gctacttgat ttaaggttgt cactcgttct tgaaaagcat tgattctcaa
     3001 ttcagaagct gctaattcat gaactagttc atctttaatt gtaatataag agtgcttatc
     3061 cgtatccagc tcaagtaaag tatacacttc ctcaatcttc tcctttatca tctccacagt
     3121 tgttttcctg cggaacggaa ttgtttgatt ttcagagctg aattggcgaa ttaatgttct
     3181 acctttcata tagcaatttt tctcggcatc atctttgtaa tagacatagt aggagctcgt
     3241 ttctctgata aaaaccttca ccttatcctc ctccatatcg agctccatgt taggcaaaaa
     3301 gataagccct tcctgacgaa taccaaactt gaccttgatg taaataccat catccactac
     3361 tttttcaatt tgattgagtg acaactctac ctcaaattca tgaatagcat ctctatttct
     3421 cctgaactct tgataggact cccaaaactt ctcctcgctt gggagttctt tttcttttga
     3481 gaatctttct tcttgataaa cttgaactaa atcctgaact tctggagctt tcaaatcttt
     3541 tctcttctca aaataatctt tgaaaaactc tacatcatat aagtttttct tgtctagttc
     3601 tgtttctttc acttctactc ctgcaaattg aaaagaaaca tgcttttgct taggattgat
     3661 atttaatcca aatagttttg cttttttaat cagatcttct aagttatcaa ccttgggtaa
     3721 aataaattcc ataagctctt ccattttcct ttttgcgaag taattcttga aaaattcttc
     3781 tgtgtaagct tgcttgtgat tgagtttatt accacgcacc acttgtctca tagttgagtc
     3841 cgtcataaaa aaggtagcat gcttgtgact gaaatccatc ttcacatgta gtaatggagc
     3901 gttctttttg aaatcctcaa aatcggtaga attttccatc aaaaaataga gtcgttgctt
     3961 aagttcatac ttgtgattgg tcttacgata aactttatac tgatggtaag aatagcgatt
     4021 ctcaataatt tttgcacctg caattttaga aaatctatct gaaatcatgc gaagatttcg
     4081 ttcgacttta taattccact ttagtttttt gtccgaattg ttatcaaccg aattaacaat
     4141 gatatgatta tggaaatgat ttttatcaac gtgagtcgca acgataaaac gaaatttacc
     4201 accagttaac tccttcattg tctcatagcc aatctgattg atttgtttag gagtgagatg
     4261 atcttcgggt gaaaaggact gaatgatatg atgagcatga attagtcgtt gattttcctc
     4321 atgcctgtcg tggcgaaaat cgtaaagcgt atcattactg ataaaatttt catgatacat
     4381 ctgcaccatc tcctcataac taggaaaatc cagaaaattc ctcatgccat agtgcgatac
     4441 caatgcaaga ttttcggtct tctcaggatt gagaatatac ttgataattt ttttgcgata
     4501 acactttccg tgaacggcaa aatgcttagt gatgaccatg aaactccctc aactttttag
     4561 cttgaatact aaactctttc tctacctctc ttatcaagtc agcgattccc tttttcaagt
     4621 cttgcaattc ttcacttgaa atcaactgag attgattgac acttcgggca atctggttga
     4681 tgttattacc aatcctcttc aactcaaata ctaaatcttg ataaccagtt gtatcaatgg
     4741 tgatgaaatt cataccaggg tcaagtagag ttcgtcgagc atattctgaa aaagattgac
     4801 aaccgctttg gtcgatacaa tgtttcaact gacccaattc gctatcagac aggaaaactt
     4861 tctttagatt ggttcggtaa cgattttcca tgtgcctacc tcatgtattt tttacggaag
     4921 tcttgactaa gagaaatgga attccctatt tcttgaatca attcctgaac gcaggttaag
     4981 agaatggata cgtgttcttg ggtgacttga tgttctgccc ttgataagat taaaatctca
     5041 taaacatcac gactgatttg ttccaacttt tgagctcgcc agaaggtgaa ccacttttca
     5101 gcagtcattt ctaactcgtt ctccagtaac ttgtttctgg caaatgaaga aaagtgttca
     5161 aatcctttat ttttcatcat tacgccaatc atttctaatt catttgcggt caaattaacc
     5221 tctttgcgaa tgtctctgta ttgttctggc atactacttc ctcactttta tctattgtcg
     5281 gataattccc gaccccgtgt caaccacggg aaacttataa aaacaaaatc tatcatcttg
     5341 taaggctttg cgagctcaga tattgtgtcc acaatatccc aaaaatcata tcgccagcta
     5401 atcaaaacct accagttttg acagctaacg ataagataac ttggtggctc cgcccccaaa
     5461 cccccagtga agatttgagg ttttattttc ttaagaatga tataagaata gcagagaaaa
     5521 tttggaaaag atatcacagg agaatgagag gatgaaaaaa agagagcaaa tgctctcaat
     5581 gaactcatat aaatatatat caaaatactc ttcaaaaaca taaggttcta aagattatgt
     5641 agaaaaagct ttagcaagtc ttaaacactc tgttgctcta acttatactg gtcgatgcta
     5701 aaataattta attccttgaa gtaattttcc agcttttaaa tgatactctt gatttttcat
     5761 ctcctctaaa cgactatcta cagctaaggc aaatatattc catattacat tccatcttcg
     5821 tatcttgttc ttgtcatata atcttaaatg tcatagagca tggatttcat attttgataa
     5881 ttaggtattc ctaccaatgc tcgactagct ctatttatcc cttcaacata accctttgag
     5941 tcattcaata taccaaaatt ccagaacctt ttagaattat tcggtgtcta gttgtaaccg
     6001 taatactcgt aaaatggcta atgtagtaca atcatcttca ttttttattt ttcaactcct
     6061 gcactattaa aatcaatgtg ccaattaatt gcagaaccta aaacacctgt aatatcaaat
     6121 tgcaatctat cttgatttag actagtcaaa tatatcttct ttctataaaa tcttcaaaag
//
LOCUS       DAVLUM010000090         6101 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLUM010000090 DAVLUM010000000
VERSION     DAVLUM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.090"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(101..376)
                     /locus_tag="VYN42_001858"
     CDS             complement(101..376)
                     /locus_tag="VYN42_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1462890.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(483..1322)
                     /locus_tag="VYN42_001859"
     CDS             complement(483..1322)
                     /locus_tag="VYN42_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1462891.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSRVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1464..2312
                     /locus_tag="VYN42_001860"
     CDS             1464..2312
                     /locus_tag="VYN42_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1462892.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2405..3322)
                     /locus_tag="VYN42_001861"
     CDS             complement(2405..3322)
                     /locus_tag="VYN42_001861"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1462893.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3760..3965
                     /locus_tag="VYN42_001862"
                     /pseudo
     CDS             3760..3965
                     /locus_tag="VYN42_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1980 domain-containing protein"
     gene            complement(4170..4463)
                     /gene="rpmA"
                     /locus_tag="VYN42_001863"
     CDS             complement(4170..4463)
                     /gene="rpmA"
                     /locus_tag="VYN42_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1462894.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4480..4824)
                     /locus_tag="VYN42_001864"
     CDS             complement(4480..4824)
                     /locus_tag="VYN42_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1462895.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4840..5154)
                     /gene="rplU"
                     /locus_tag="VYN42_001865"
     CDS             complement(4840..5154)
                     /gene="rplU"
                     /locus_tag="VYN42_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1462896.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5190..5277)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5342..6040)
                     /locus_tag="VYN42_001866"
     CDS             complement(5342..6040)
                     /locus_tag="VYN42_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1462897.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIGFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
BASE COUNT         1872 a         1262 c         1008 g         1959 t
ORIGIN      
        1 aacattcaac tttttaactc tatttattac tagatttcat aattaaaaag cctactgacc
       61 aagctagaaa gcttgataca ataggctttt taaagactga ttatttaaca gcgtctttaa
      121 gagctttacc agctttgaat gctggtactt tagaagctgc aattgtcatt tctttaccag
      181 tttgtgggtt gcgaccttta cgttctgcgc gctcacgaac ttcaaagtta ccaaaaccga
      241 tcaactgaac tttttcacca gctgcaagat agtcagctac tgctgcaaat acagcttcaa
      301 ctgctgctgc tgagtctttc ttagtcaatt ctgtagcttc tgctacttta gcgatcaaat
      361 cttgtttgtt tgccatgtta atgattcctc caaataattt ctaattaaca aatataatca
      421 tatcctaaaa tcccttttag gtcaagttaa aaacgctatt tcttcccatt ttatttattt
      481 ttttaggagt ggtaacgtat caaaatagcc caagcgttct cacccgtgtg agtttgaata
      541 atggaacccg tttccaaaac agaaattggc ttttcaacat aagcttgtaa gctttctttc
      601 atctcttttg cccaatcatc actaccagaa tatgaaattc caatctctgc tacagcacgt
      661 tcagaaagcg atgttatcaa ctcatctaac cattttttaa atgttttagt tccacgacct
      721 ttaaccattg gctgcaattc atggtctttc atttgcatga caacacggat attgagaaga
      781 gagctcaaca agccagttac acggctaatt cgtccacctt tgacaagatt ttccaaagtt
      841 gaaacaccaa tataaagctc tgtatggttt ttaacctctt ctacacgaga taaaattgcc
      901 tccatatctt taccttcttg agctaacttc gcagcctcaa caacttggaa tttcagggct
      961 tggtcagtga aggaactatc aacaacagtc acatctgcag tagataggct agcaccttgg
     1021 cgtgctgctt ctaccgtacc cgaaagagca tgggacatat gaatagcaag aatctggcca
     1081 ccatctttgc ataggtcttc aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt
     1141 ttcggaagat tcttactttc ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc
     1201 gcatcagaat aaacaacatt atcaatcatt acagataatg gaacaattgt aatatctaat
     1261 tgctttacta gttcaggttc aatagtaaca gatgaatcgg ttacaatctt aatttttgtc
     1321 atagtatcaa tctttctatt ttaggattca gattggtttc cttacttcta attatatcaa
     1381 aaaaaagatt aaaaatccta atggagtcaa tcaaattttc cgtaaaattt gatataatca
     1441 acttataaga aaagaggtgt cctatgatta aaaaaattta ccccattttt accattttac
     1501 taggtgctgc tatttatgct tttggactga cttattttgt agttccccat catctctttg
     1561 aaggaggggc gacaggcatt accctcatca ccttttatct ttttaaaatc cctgtttccc
     1621 tcatgaacct gctgattaat attccccttt tcatcctagc ttggaagatt tttggagcca
     1681 aatccctcta ttctagttta ctaggaacct tagctttgtc cggctggtta gctttttttg
     1741 agcatattcc ccttcatatt gatcttcaag gtgatttact aatcacagcc cttatagcgg
     1801 gaatcctatt gggaattggc cttggaatta tttttaatgc tggaggtaca actggcggaa
     1861 ctgatattct agctcgtatt ctcaacaaat acactcatat atccatagga aaactgctct
     1921 ttatcttaga tttttgtatt ctcatgttga ttctcctaat cttcaaggat ttgagattgg
     1981 tttcctacac gcttttgttt gattttattg tttctcgtgt tattgatttg attggtgaag
     2041 gaggatatgc cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa cttgctaagg
     2101 cgattaatga tgacctcgga agaggtgtta cttttatttc tggtcaaggc tactatagta
     2161 aagaaaattt gaaaatcatc tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg
     2221 aaatgattca tcgaatcgat cctcaagcct ttataactat tacagaagcc catgaaatcc
     2281 taggagaagg cttcaccttt gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt
     2341 tagactaaat catctatctt ttgggttaca gacaacctct tttttatttt atttactcaa
     2401 gctcttaaga ccaattccga gttacttctt catcagcctt taactgatcc actaattggt
     2461 caactgagtc aaatttggtc atatcacgaa tgcgatcaag ccaataaacc atgacggttt
     2521 ccccataaat atcttgatta aaatcaaaaa tattgacttc aaaacgtgct tcttctccat
     2581 caaaggtcac atttttcccg acactagcca tagcacgata cttctgtctt tgaatctcaa
     2641 catcaacgac ataaacgcca tctgctggca tataagtacg gtctaaaagc actaaattcg
     2701 ctgtcggata accaattgta cgaccacgag cattaccatg aaccaccata cctcttgatg
     2761 gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt tccatctaaa atagcttgac
     2821 ggatacgagt tgaactaatc tttcctttct catcttctac aggtggaaca atgataactt
     2881 ctccatcaaa gtaatccttt aaatcttctg ctgttttttt gtcagaacca aatgtataat
     2941 caaaacctgc aacaataatt ttggcattca tagccttgat ataagttgca aagaattctt
     3001 gtgcagtgag actagcgaat tgactactaa aatcaaggag atataattct tctacacctt
     3061 cgcgctttaa ttttctttca cgttcagcag ggttcaaaat atgcaaaaac aaatctggat
     3121 gataaggctc taaagcgatc tttggagatt cattaaaggt cataacgacg ataggtaata
     3181 aatcctttct cgcagccttg ttggcaacac gaaataattc ttgatgcccc ttatgtatgc
     3241 catcaaaata gccgagaaca acgactgaat cagatggtgt gccaatatct ttttggtttt
     3301 ttataggaat agtaataatc ataaaataat tatatcatag cgatagctat ttctggaaca
     3361 gaaaatctga aatgttgttt ttttcacatg aagtgtacct gttttcaaaa agcactttat
     3421 tctatcgttg cttaactatg aactttgcaa tattcttctc aaaaacttgt aggacatctt
     3481 caaaattttg caaggagtga ttagacttgt tcggtaacca taaagtgtca tactatgctt
     3541 atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat tggtgccgaa
     3601 aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa tgagacaact
     3661 tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc actttccctg
     3721 atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt ccaacaactc
     3781 ccatttagtg tgcttcagac tgggctattt ttctctccat ctgttagctt ggattctcag
     3841 acagtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa accattcaga
     3901 caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat agtcaattga
     3961 aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt gttctattcc
     4021 agattcaatc cactatacat attaaaaagt atgggtacca aaacaaaaaa acaggctctc
     4081 cgaaaactcg gaaagcctta ttttaagctg tttctagctt cctcaccttt acatttcaag
     4141 gttcgggata aaaggttcaa tggacctttt tatttagcga ttgggtaaac agaaacttgt
     4201 tttttatcgc gtcctttacg ttcaaagcgt actacgcctt caactttagc gaacaaagta
     4261 tcgtctccac cacgaccaac gtttacacct ggatagatgt gtgtaccacg ttgacggtaa
     4321 aggattgatc cacctgttac agtttgtccg tcagctgctt tagctccaag acgttttgct
     4381 tgtgaatcac gtccgtttga tgtagaacct ccaccttttt tgtgggcgaa aagttgcaag
     4441 ttgttaagag tcatttttaa cataatgttt tcctccgtgt tagttttctg tgataactct
     4501 ggtttggacg aactcagaat agttctccga taagtttgcc atacctaaga aaaatgattc
     4561 aaagaataac tgggtcattt ctctctggtg tgaaggaaga tcttttggta tttcaaccat
     4621 cagatagcca ccttcatctt cgtttaattc taggattggt tcatagcctg caaatttctc
     4681 aatagaattg ataaagttaa tggcaagcgt agaaaccgat gcacacacga catctaagcc
     4741 gtattcgcca ctctcggcgt gtccagtaat ttccgcactc ctcagctcgc catcttcggc
     4801 tctctcaaag actgcctgta tcatgtgttc tccttaaaat taagcgttga ttgcgttgat
     4861 gacaactttt gtatatggtt gacggtgacc ttgtttacgg tggctacctt ttttaggttt
     4921 gtacttgtaa gtaaccactt tcttttgttt tccttgtttt tcaacagttc caactacagt
     4981 agctccagca acaagtggag ttccgacaac agtgttttca ccaccaacaa gaacaacttc
     5041 gttaaaagta acttcttgac cagcttcaac gttcaatttt tcaacgtaaa ctgcttgacc
     5101 aacttcaact ttaacttgtt ttccgccagt tttgataatt gcgtatgtgc tcattatgca
     5161 cctcctatga tttttatggg tttccccgat tttttgtgaa gactcgccta gcatcgtggg
     5221 acgaaccact taaacttgaa taatcaagca acgatgttcg tgcggttgca caggatcgtg
     5281 catagtcaac tcttcaagta tagcatatct cctattttct tacaagtaat aacacctaaa
     5341 atcaagcttt ttcttttact tttttctgcc aagaggcaaa aagcatgctg aggtaaaaaa
     5401 cgctcatcat aataggaaca ccaagaatgg tcttttcatg atagaaaatc gtcaaatagg
     5461 ctgaaaagac aacgccaagg acaaaactac taagcaggct aacaaatatg aatccttcac
     5521 gcaaaaaagg agtgtgcttg gttcggaaat aatctccaaa agccagcatg gtccgtttga
     5581 tattccctgt cataaaagcg ttattatagg caatacccga cacttctcca aaagcagttg
     5641 tcaccagtcc catacagaag gccaagggcg gcactagata gatattatcc acagtttgcg
     5701 gcacaaaacc aataatgatt gataagattg ccaagggaat caaggacaga ataggttttt
     5761 tcacaattct caatttttcc ttataaatcg ttaataaaaa gactcccatc ataaacgcta
     5821 gcaaggtgag aaccttgtcc ctaacatccg aaacattatt tttaattaat tctactgaaa
     5881 gaaagacaac atttccagtt tgtccagcta caagggtatt cccgcgaaca ataaaagtgt
     5941 aagcatccac atatccagca caaaacgtca aaaaaagtgc taacctttta gactgacgtg
     6001 atatttttct tataggtaat aacctcattt tacctcccat tgtattttct cttagaaata
     6061 ttgtaccatt ttctttctaa aaaatcgtag gctaccattt a
//
LOCUS       DAVLUM010000091         6033 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLUM010000091 DAVLUM010000000
VERSION     DAVLUM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6033
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.091"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            128..1897
                     /locus_tag="VYN42_001867"
     CDS             128..1897
                     /locus_tag="VYN42_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1462898.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGSIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNILLGVLVAAVVSFLIA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            1921..3876
                     /locus_tag="VYN42_001868"
     CDS             1921..3876
                     /locus_tag="VYN42_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1462899.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLSNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIVNEKIKKLEN"
     gene            3878..4315
                     /locus_tag="VYN42_001869"
     CDS             3878..4315
                     /locus_tag="VYN42_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1462900.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            4377..5513
                     /locus_tag="VYN42_001870"
     CDS             4377..5513
                     /locus_tag="VYN42_001870"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1462901.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1853 a         1010 c         1232 g         1938 t
ORIGIN      
        1 taatttttaa gcctttttgc ccagcctcat caaaagtaat gttttgacac aaaatctgtg
       61 acaaaacttt agttttaaag gtttttaact ttgtatatac tagttttaag aaaaggagga
      121 tgatctaatg gaagaaaaag tatcattgaa agtcagggtt caaaaactag ggacatcgct
      181 ttcaaatatg gttatgccca atattggagc atttattgct tggggagtat tgactgccct
      241 ctttatcgct gatggctatc tgccaaatga acagttagct actgttgttg gtcctatgtt
      301 aacgtattta ttgccaatcc tgattggtta cacaggtgga tatatgatcc atggccaacg
      361 tggtgccgtt gtaggatcta ttgctactgt tggtgcaatc acaggttcta gtgttcctat
      421 gtttatcgga gctatggtaa tgggcccact gggaggatgg actatcaaga aatttgatga
      481 gaagttccaa gaaaaaattc gtcccggatt tgaaatgtta gttaataact tctcagctgg
      541 tctcgttggt tttgcattat tgcttttggc tttctacgca atcggtccag tcgtatcgac
      601 tcttactgga gctgttggga atggtgttga ggctattgtc aatgctcgcc tccttcctat
      661 ggctaatatt atcatcgaac cggctaaagt ccttttcctc aataatgccc tcaatcatgg
      721 catttttact cctctgggag tagaacaggt agctcaagct ggtaagtcaa ttctcttcct
      781 attggaagct aatcctggac caggcctggg aattctatta gcttatgctg tattcggtaa
      841 aggttctgct aaatcttctt cttggggggc aatggttatt catttcttcg gagggattca
      901 tgaaatttac tttccttatg ttatgatgaa gcctactcta tttttagctg ctatggcagg
      961 aggtatctct ggaactttta cttttcaact cttagacgct ggtcttaaat ctccagcttc
     1021 accaggttct attattgcga ttatggctac ggcgccaaaa ggtgtttggc cccatctaaa
     1081 tattctttta ggtgttttag tggcagcagt tgtttctttc cttatagcag cccttattct
     1141 tcatgcagac aagtcaactg aggattcgct cgaagctgct caggcggcta cccaagcagc
     1201 taaggctcag tctaaaggtc agttagtatc aacttctgtt gatgcagttg tttcgacaga
     1261 ctcagtggaa aaaatcattt tcgcctgcga tgctggtatg ggaagctctg ctatgggagc
     1321 tagtattctt cgagataagg ttaaaaaagc aggtctagag attccagtat ctaatcaggc
     1381 aatctcaaat ttgcttgata caccaaaaac attaattgtt actcaggaag aactgacacc
     1441 aagagctaaa gacaagagtc caagtgctat tcatgtttct gttgataatt tcttagcgtc
     1501 ccctcgttat gatgaaattg tagcttcatt aacaggagct tctccaatag cagaaattga
     1561 aggagatata ccaacttcag caccagtaga tagtcaggaa attgacctta accatattga
     1621 tgctgtagta gttgcttatg gtaaagcaca gggaactgca actatgggct gtgaaacgat
     1681 tcgggctatc tttagaaaca agaatattcg tattccagtt tctactgcca aaatttcaga
     1741 attaggtgaa tttaattcta aaaacataat gattgtaaca actatttctt tacaggcaga
     1801 agtgcagcaa gcagcaccga attctcaatt tcttattgtg gatagtttag taacaacacc
     1861 agaatatgac aaaatggctg ctagaatgta caaatagaac tagaggtttc taaattacga
     1921 atgctattaa ccaaacgaga agaacaatta ttgaaggctt tcctacatgt agggaagctt
     1981 tcaatgcaag atatgactga aatcttacag gtttcatcta gaacaattta tcgaacttta
     2041 tcagatttga cagatagcat ggagcaatat ggaatcgaaa taacgaagca tgggaaatac
     2101 tatattttga ctggagagtt ggatgatttg ccgacagaac ttgaagtgtt agttgagtat
     2161 agtccccaag aaagacaaga gttgattacc tatcgccttc tgactgagag cggttttgtc
     2221 accaatgaag cattgcaaga gtgcacgaaa gtcagtaatg taactattat tcaggatatt
     2281 tcagatattg ataagcgtct tttagacttt gatctgaaaa ttgaacgaca aaaaggttat
     2341 cggatttctg gtgattcagt tggtaagaga agatttttgg ctattttact gacaaactgt
     2401 atctcagtag cagatttttc aaccggtaat tttgggagct ttgatatttt agaagcagat
     2461 agaactaggc tggccagtca gattgttaat aagcaactgt caggttttcc agatatggat
     2521 gctaggatga agatgttttt tgcgatcttg ttatctctta taggtcagga gcaaaacatt
     2581 gaaaattcac ctaatactag taagcaggct ttggaaattt ctcaaaaaat ttttcaaact
     2641 tactctaagc agactgcaca attttatagt attcaggaaa ttatctattt tgcgagcatc
     2701 ttggatgaat taatcattaa acgtcaggac aatccgctct ttacggagaa atttgatggt
     2761 gaatttttct acaatatttc aaatctgatt gatacggttt ccatgtatac caagattgac
     2821 ttttttaagg acaaggtttt attcaatttt cttttccatc atattcggct cagtttaggc
     2881 gtccctatcc tttttcaggg tgaaaatttg ccagaatctg tccagatttt agttgaaagg
     2941 aataaatttc tttatacagt catcagtctt ttagtgaatg atatttttcc gaaatatctt
     3001 catacagagt atgagtatgg catgattgcc ctacatttta tctctagctt aggccgtagt
     3061 ccagagattt atccagtccg tgttttgctt ttaacggatg aacgtcgggt cactagagat
     3121 ttattagtca gtaaaattaa gagtgttgct ccttttgtag agttgataga tattcagtct
     3181 ctagtagatt accacagtat tgatctcagt cagtatgatt atattttatc taccaagccg
     3241 ctgagtaatc aggaaatcga tgtaatttct agttttccaa ccgtcaaaga attgcttgaa
     3301 ttacaggaac gacttcagta tgtacaggca catcgtacaa ttgtcgcgcg tgatgctatc
     3361 gctccagaga aaagttatga cttgcaagat tatttaatat ctagtagtca gcttttgagt
     3421 caatttgagt tggttcaatt ggagaataat caatcatttg agcacacggt agaacaaatc
     3481 atccaatatc agaagaatgt gagtgacaga gattacctaa caagaaaatt gttatctcac
     3541 ttccagaata gtcctatggc tattcctaat actggtctgg tgcttttaca tagtcagtct
     3601 agcaaagtaa caacaaatag ttttactatg tttgaactca aactacctat ctccgcattg
     3661 tcaatgaaac gagaggaaga agaggtcaaa aggtgtctgc taatgctaat gtctaaagaa
     3721 gctagcgagg aagctagaga tttaatgaca gctattagtc agtcgattat tgaaaatcat
     3781 ctttatacag agatttacaa gacgggaaat caatccatta tttatcagat gctaaatact
     3841 attgttaacg aaaaaattaa gaaattggag aactaatatg aaacttgaaa aacatttgat
     3901 taagcttaat aaacaatttt ctaacaagga ggaagctatt tgttattgtg ggcaagttct
     3961 ttatgagggt ggatatgtta atgaagacta tattgaagcc atgattgagc gagataaaga
     4021 gctatctgtt tacatgggta actttatcgc cataccgcat ggaacagatg cagcaaaaaa
     4081 tgatgtcctt aagtctggta ttacagtcgt tcaagtccct agaggggttg attttgggaa
     4141 tgtatctaac cctcaagtgg caacggttct ttttggtatt gctggtattg gtaatgaaca
     4201 cttagaaatt attcagaaaa tttctatctt ctgtgcagat gtggataatg ttcttaaact
     4261 agcagatgct cagtcaaaag aggaagtatt gcgcttattt gatgctgttg aataattgaa
     4321 tttcgtcatt tgtcatctag tatatatgtc cctcaaatag gaaaaggaga aattgaatga
     4381 aacattctgt tcattttggt gccggtaata tcggtcgtgg ttttataggt gaaattctat
     4441 ttaaaaatgg tttccatatt gattttgtgg atgtcaataa tcagataatt catgctctaa
     4501 atgaaaaggg caagtatgaa attgaaattg cacagaaagg acagtctcgt atagaagtaa
     4561 ctaatgtggc tggcattaat agcaaagaac atcctgagca agtcattgaa gcgattcaaa
     4621 agacggatat tattactact gcaatcggac ctaatatact cccttttatc gctgaacttc
     4681 tagccaaagg aatcgaagct cgccgagttg cagggaatac acaggtattg gatgttatgg
     4741 cctgtgaaaa tatgattggc gggtctcaat ttctttatca agaagtcaag aaatatttaa
     4801 gtccggaagg tttgacattt gctgataact acataggttt tccaaatgct gcagtagaca
     4861 ggattgttcc agcacaaagt cacgaagatt ccctttttgt tgtggtcgag ccctttaatg
     4921 aatgggtcgt ggaaaccaag cgtcttaaaa atccagattt acgtctaaaa gatgtgcatt
     4981 atgaagaaga tttagaaccc tttattgagc gaaaactttt ttcagtcaat tctggacatg
     5041 caacttcagc ttacattggt gcgcattatg gtgccaagac aattttggaa gctcttcaaa
     5101 atcctaatat caaatctcgg attgaatctg tattagctga aattcggagt ctcttgattg
     5161 ccaaatggaa ctttgataaa aaagaattgg agaattatca caaagtcatt atagaacggt
     5221 ttgaaaaccc tttcatagtg gacgaagtta gtcgcgtagc tcgtactcca atccgaaaat
     5281 taggctataa tgaacgattc atccggccga tacgtgaatt gaaagaactc agtttgtcat
     5341 ataaaaacct acttaaaaca gttggctatg cctttgacta tcgcgatgta aatgatgaag
     5401 aaagtattcg attaggtgaa ttgttggcta aacaatcagt caaagatgtt gttatacaag
     5461 ttacaggttt agacgaccaa gaattgattg agcaaattgt agagtatatt taatcttttt
     5521 cgaaaatctc ttcaaatcag gttagcatcg ctttgtctta ggcatatgtt actgacttcg
     5581 tcagttctat ctacaacctc aaagcagtgc tttgagctga ctccgtcagt cttatctgca
     5641 acctcaaaac actgtttgag ttatctgcgg taatctttct agcttgtctt tgatttttgt
     5701 tgttatttat aaggtaaaag aagctggaca aaaagtcttc aaaatcggga aaaggcagcc
     5761 tatcgggtgt tcaaaaatct tgataggatg tcctttatta tggaaagcct tattggattt
     5821 tctcctcaga ttgagttttt gatcagcttt atgagatagg ttttgctaga gatgtagccc
     5881 atcatgttat ttttatggac agtgggaaaa ttgttgaaaa aaataatgcc catcaattct
     5941 ttagtggtcc aagagaagaa cgaaccaagc aattttggaa cgaattcttt cgaatgcgat
     6001 ctatatagta aaatgaaaca agaacaggac aaa
//
LOCUS       DAVLUM010000092         5991 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLUM010000092 DAVLUM010000000
VERSION     DAVLUM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.092"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..738)
                     /locus_tag="VYN42_001871"
     CDS             complement(<1..738)
                     /locus_tag="VYN42_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1462902.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKL"
     gene            complement(740..1297)
                     /locus_tag="VYN42_001872"
     CDS             complement(740..1297)
                     /locus_tag="VYN42_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462903.1"
                     /translation="MARTELPDKIEIERLVLRVRTVADAEDIHVYASLPEVAYPAGFL
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(1284..1775)
                     /locus_tag="VYN42_001873"
     CDS             complement(1284..1775)
                     /locus_tag="VYN42_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEV1462904.1"
                     /translation="MTTCSSSCSLGDWVVIGVVARENAAEQIKQYQKFTVNISDETSM
                     LAMEQAGFISHQEKLERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFA
                     KILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKD
                     GKN"
     gene            complement(2145..2540)
                     /locus_tag="VYN42_001874"
     CDS             complement(2145..2540)
                     /locus_tag="VYN42_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1462905.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGINSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(2636..2890)
                     /locus_tag="VYN42_001875"
     CDS             complement(2636..2890)
                     /locus_tag="VYN42_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1462906.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(2900..4234)
                     /locus_tag="VYN42_001876"
     CDS             complement(2900..4234)
                     /locus_tag="VYN42_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1462907.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEVFEAFAIEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDVYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(4234..4467)
                     /locus_tag="VYN42_001877"
     CDS             complement(4234..4467)
                     /locus_tag="VYN42_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1462908.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            4498..4572
                     /locus_tag="VYN42_001878"
                     /pseudo
     CDS             4498..4572
                     /locus_tag="VYN42_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4927..5109)
                     /locus_tag="VYN42_001879"
     CDS             complement(4927..5109)
                     /locus_tag="VYN42_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462909.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(5111..5890)
                     /locus_tag="VYN42_001880"
     CDS             complement(5111..5890)
                     /locus_tag="VYN42_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462910.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         1759 a         1355 c         1038 g         1839 t
ORIGIN      
        1 caacttatta taattaccat agagctctgt aagagcatta aagtattctt tcactagagc
       61 tatagcgtca atcttagatg tttcttggtt tagttttatc aactcccctt tcaatttttt
      121 ccatttaaag ttggaattta aaagataatc taaatcaata tagaaatcta ttataacagt
      181 ctcatcatct gggctaacag cttttacctc atttattggt aagtcagtat gttgcgaata
      241 atttctcaaa gaatggcaaa atcgataagc aaaattggta tcatactgat agcttgcaaa
      301 accatgtata caatcaaact cctcactatc tttggaatat ttttgtttaa tttggttttc
      361 gttaaaatcg acaaacaatt ttccactgga taataaatga atcatgaaac gatttacatc
      421 tgcctcttca atttctaatt cctttgactc aagtttattt ttaatactta aaaaatccga
      481 gacatctgaa ataaacaatt cgaacatatt cttgattttt tgaaaattct tttgaatctc
      541 aaaaatttgg tccgagactg acattatttc cttggttggt tcaatatcag agatgacaat
      601 acgtttttca ttgttgttaa tttctaaata agctaatcgc tcgataatat cactatcatt
      661 taattcagca tactcaacat caatttggcg taactgcttc tcagatagag agcttacttc
      721 ctcttttaca tcgctcatct tattcctccc actcgctctt cagcaagcca tatatcagac
      781 tgtcacagcg gtttccttga acatcctttc ggtctcttat gcgagcttcg agggtaaagc
      841 caagcttttc cgcgactcgt ttactttgaa ggttatatcc aaagcaagtt agttcaatct
      901 tgtgaagacc aagttcttta aaagctagat caatcaaggc acacgctgct tctggaacat
      961 aacctcgccc ccaatagtct gggtgtaagg tatagccgat ttccagcaca tcatcttcat
     1021 ggcgatggtt gaaatcgaca gagccaacga tcttatccgt tcctttgacg acaatcccgt
     1081 agcctgctgg gagattttcc ttttgattac gctccggaag aatgtgctcc agataataaa
     1141 tctcatcttc caaggtcttg acgggcagaa aacctgctgg gtaggcgacc tctggcaaac
     1201 tagcatagac atggatatcc tcagcatccg ccactgtgcg gactcgtaaa acgagacgtt
     1261 ctatttcgat tttatctggc agctcagttc ttgccatcct tcttcctcgc ttttttgatg
     1321 aaactgccct tcatatctac acgcttgtcc agatagcgat aaacgcgctg atatccatct
     1381 cccatgaaat aggttggggc aaacagttga tttttaaaat gtcccttttc atccaggagt
     1441 tctggggcaa caagtcgctc aagaatcttg gcaaagatgt ggcaaatacc gtcttcctca
     1501 acaatcctat ctacccgaca atctaaaaca agtggacagg cgtctaaaat aggagtctga
     1561 gttcgttcag aaatttcata atgcactccc aaacgttcca atttctcctg atgactgata
     1621 aaaccagcct gctccatcgc aagcatagaa gtttcatcag aaatattcac agtaaatttt
     1681 tgatactgtt tgatctgctc tgcggcattc tctctcgcaa cgactccaat cacaacccaa
     1741 tctcctagac tacaagagga actacatgtc gtgatgttat agccaaaatt ctaatcttga
     1801 tatcctaaaa taaaaacagg aaaaccatag tatagtttac ttgtgttaaa agattgcttc
     1861 ataacaaccc cctttgacta agacgtaaaa gaaaagccct gccatctaca tgacagggac
     1921 gaatgtgttt atccgcggta ccacccaatt tcgggccaag cccgcatctt tagtctttaa
     1981 aataaaaaga cagaaatatt tcattttttc agtcattagc aaccagtttt gacacatttg
     2041 tggacttctc agcgccgcca ctttctgtaa aatgtgggat tcaaaacacc tctaatggct
     2101 ctattgtagc aagtttttct cggaaatgca aggctcaaga aaaattactt gaacttgatg
     2161 ccattttctt tcaatttctt aatggtagct gggccgattc ctttcaaagc aaggagttct
     2221 ttttcagtcc agtttttgaa atctgaagca gaattgattc cttcatcata gaaagtcttg
     2281 gcacgatcaa gtggaagtcc acccaagttt gctgcaaaat cttctacaga attagctact
     2341 ttttgagctt gctctttggt agcttctact gcttgttcaa cttttttaga aacagcctta
     2401 ccagctgcgc ttgctgactg ttctgcacgc ttcacgactt tttttgtctc atctacaacc
     2461 ttagtcacag tacttgaaaa ggcacctgcg cgacggaggc catttcgtaa ttgtttttta
     2521 cgattgagtt tctttgacat gataaaatcc tttcaataaa aaatccctgc tctgacaagg
     2581 atttaacata aacattctat caagatttta gtgaaaaatc aagaatcttt ctcgtttaat
     2641 aatttcgctc accaaacaag ccttctggca aatcatggaa tcccttgcct actttgaagt
     2701 tttcaaactt accaagcaag aactgataag catccaagcg actctcgtag cgaatcatgg
     2761 catctttggc acgctcgtcc tggtcttctt cgtaaacttt ttggctttcc ttgtgcgcca
     2821 tgtcgttaat catgatttgg gtattgaccc aagcttcaaa ttccttcata aattcttgtt
     2881 cgtaactcat tttttctcct tattctaatc cacgaaaata gtccgtatca atctcacggt
     2941 agggctggat atcctgaacg tattccagta caccttggaa ttctccgttt tcatcgtgta
     3001 ctgcagcata ggtgatgtgg acaaacttgc ctcgcgactc agacttgaac cacatttcat
     3061 acttgtcctt ggtcccctca cgaagtccct tcatgatagc cttgaccttg tccaaatact
     3121 taggcggatg acagagttcg acattgcgcc cgacttggga cggcgtccgt ttgaaaatca
     3181 tctcatcagc tggcgtattg tcattgtaat actggaaaat atcttcttta ttgacaaagg
     3241 taatctccat agggagatga ttgaggatga gattggcctg ctcgactgaa agatagccat
     3301 taccaaaagc ctgttgacta tggcggtcca gcacagcttc cttttcctta ggggtaaagg
     3361 taatggtaaa atggccttct ggcgtatcta tgacttgttg aacttgacct tctgccgtat
     3421 ctagctgtac aggctcctct gcaatctttt cctcaataaa gctctgtcgt tctggcaccc
     3481 atttctctga cggacggatg atggcatagc catagacatc gctctcctcc gcaatctgaa
     3541 gccagtcatc ctgagtaaaa gactcaagga gaatcatgag gaggatggac tcttccttga
     3601 aaatcatact ttcaaactct atcgcaaaag cttcaaaaac ttcctttaca ctgctaattg
     3661 acacttctgg tagtgacttg gctgtcgtta gagctgtttg aaagagttcc ctaatctgat
     3721 catccactcc ccacataact ttgggaggtg aatcgtgtcc atagcgctcc atgataggaa
     3781 agaagagttc ttctttacgt tggtaatgga tgtcaaattg ccccacaagt cccatctgac
     3841 gcaccaagcc cttgcgcatc tccgcaagca tttcctcgtc ttccatcaac tcataggtat
     3901 ctaacaatct acgaatgcga atcaaagctg cacggagggc caaattttct tctttgaaga
     3961 cacgaactgg gtgacctgga tgctcagtat ctgaaacttc gacacctttg atagcatttt
     4021 taaaaagatt ggcatggaca tcacagagtt ccataacatc ttcaaaggtg acacctgagt
     4081 ctgagttcat cagctcgtgc tccataaggg aaatctcaat ggctgagaca cccgcaaagg
     4141 tcgcatcaaa acgctcctga accgactcag gagaggcgcc attatgcaat tctaataaaa
     4201 tatcccgtag gacatgaatc cgttcatctg ccattagtct aatccaatca cttcgtagcc
     4261 attcgcttcc agtgtgcgta caatcttgtc cataggagtt cctgctagct tagaaccctg
     4321 tttaagtgat actttacgac caactgtatt gcgcattaag ggattggcaa ggggtttaaa
     4381 acccagctcc actagaattt ccaagacttc tggatgcttg tccaccactt ctgcaacagg
     4441 aattgacaca tcgatgatat tgtccatgac gacctccatt atatgttcta atactcaatg
     4501 aaaatcaaag agcaaactag gaagctagcc gcaggttgct caaaacagtg ttttgaggtt
     4561 gtagatagaa ctgacgaagt cagctcaaaa caccgttttg aggttgtgga tagaactgac
     4621 gaagtcagta acatatatac tgcaaggtga agctgacgtg gtttgaagag attttcgaag
     4681 agtataaaat gattttactg cttatattat accatatgga gagagattaa aaaactagca
     4741 gtggagttcc tgctagctct ctgcgacttg gattaccatc tagataagtt taaagagcca
     4801 atccaatatc ttaaataata tcttgtaaaa cagcaattga actgcaaaag aaatgatcat
     4861 ccaaaagaat ttcacaatcc caataatcgg tttgataaaa agaatagcaa gaagaccaaa
     4921 aaaatttcat tctctctcct ctggcttaat gagccaccga gccgtatcca ttagcttatc
     4981 tgcaataaaa agtttgccca gaccaacaac gacatggtca gctttcttta tcgttttcat
     5041 cacttttaca ccttgcacgg tcaaaaagta attaccataa attttagcaa aagctttgat
     5101 aggattcata ttactctcct ttgatgattt cagcctcttt tcggattgtt tcaacatctt
     5161 cttgatattg aacttcacta tagttgacta gcttggataa ttctttctgc aagctttccc
     5221 ccattggttt catagttgca aaggttaaac cacctgaaat gataccaccc aagataggaa
     5281 taaatttccc tattcctttg gccagccctc ccttggtaag attcacacca aatattctta
     5341 agactttttt caaaataggg taccaaagcg tctttgttaa agctttatta ggcactgttt
     5401 tcattacctg tttggcaatt gttataccac cagcacgtag caaagcagcg gttccattca
     5461 cccctaacat tacgcctaga taaagcaaga gggtattttg agcatcttca ctcaactcct
     5521 cgcgtgaagc ccaaagatcc tcataaccat aaatataacc taattcttga gccaatttca
     5581 gagagaaagc ataaaattga gccacatcag ctggaatggt aattgccata gcaagccctc
     5641 cagctaatcc tgccaaaaca gaagtcccac tcgctaataa tacattgtcc cgaatacaag
     5701 cattagctac acgatctaat atttcttgag atagaagagt cgttgtacct tgttccaata
     5761 aggtaggaat atcttttgga tccaattctt tggaaaactt atccactaaa aatttcgaac
     5821 gatcaacctt aacaacaggt agtttcacca cttgttgcaa tacttgcata gctaagtctt
     5881 gttcagccat atacaaactc cttatttctt ttttacacct tatcatatta tatttcctac
     5941 aaaaaaagca ttttctaatt agataacatt aaaaaataca gaaccccttt t
//
LOCUS       DAVLUM010000093         5827 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLUM010000093 DAVLUM010000000
VERSION     DAVLUM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.093"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            1..1018
                     /locus_tag="VYN42_001881"
                     /pseudo
     CDS             1..1018
                     /locus_tag="VYN42_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1134..1937)
                     /locus_tag="VYN42_001882"
     CDS             complement(1134..1937)
                     /locus_tag="VYN42_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1462911.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2212..2967)
                     /locus_tag="VYN42_001883"
     CDS             complement(2212..2967)
                     /locus_tag="VYN42_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1462912.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(3037..5688)
                     /locus_tag="VYN42_001884"
     CDS             complement(3037..5688)
                     /locus_tag="VYN42_001884"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1462913.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVADHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGSEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(5700..>5827)
                     /locus_tag="VYN42_001885"
     CDS             complement(5700..>5827)
                     /locus_tag="VYN42_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1462914.1"
                     /translation="YDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
BASE COUNT         1773 a         1214 c         1121 g         1719 t
ORIGIN      
        1 cgttacggaa tagagttcgt caaaaaaggg aaaaatcgtt actattctcc tgatttaaaa
       61 caagaaatga ttaataaagt ctgacatgaa ggctggacta aagatagagt ttctcttgaa
      121 tactgcctcc caagtcgtac gatacttctt aactggctag cacaatacag gaaaaacggg
      181 tatactattg ttgagaaaac aagagagaga gtacctgaga gcggagaagg ccatcctaaa
      241 aaagttaaga gaactccgat tgaaggagga aaaagagaaa gaagaaagac agaaattgtt
      301 caagaattaa tgactgagtt ttcgttagat cttcttctaa aatccattaa actagctcgt
      361 tggacctact actatcactt gaaacagcta gataaaccag ataaggacca agagcttaaa
      421 gctgaaattc aatccatttt tatctaacac aagggaaatt atacttatcg tcgggttcat
      481 ttagaactaa gaaatcgtgg ttatctggta aatcataaaa gagttcaagg cttgatgaaa
      541 gtactcaatt tacaagctaa aatgcgacag aaacgaaaat attcttctca taaaggagac
      601 gttggtaaga aagcagagaa tctcattcaa ggccaatttg aaggctctaa aacaatggaa
      661 aagtgctaca cagatgtgac agaatttgcc attccagtaa gtactcaaaa gctttactta
      721 tcaccagttt tagatggctt taacagcgaa attattgctt ttaatctttc aacttcaccc
      781 aacttagaac aagtacaaac aatgttggaa caggcattca aagagaagca ctatggtgga
      841 atccttcttt gggattctga aatcggaaat gttttacggt tatgagaagt cgtttcagtc
      901 gcttaagcaa ttggaacaag ctattgtaga ctatattgat tactacaaca ataaacgaat
      961 taaggtaaaa ctaaaaggac ttagccttgt gcaatacaga actaaatcct tcggataaat
     1021 tatttgtcta actttttggg gtcagtacac ctaaaacttt gatgatatac gttttcttgt
     1081 gagaatattt acttcatttt tgcctaaaat tcaatgttta ctcagtattt ggattatgaa
     1141 aaatcgaggt ctaaatctag atacattttt tctgaagaca aatcattttg accaccgagc
     1201 aagagatttt caaaaaaagc tgttaaaaac tcagaacgtc gctgtaaaat ctttgcatta
     1261 tctaatacca aggcatcacg aaaatatttg gaatgttgct gaaatggtgt attatcaata
     1321 tcaaaaccaa actcacgaag atactgaatc aaaaagaccg ttactgtccg agtgtttcct
     1381 tcgcgaaatg gatgaatctg ccagattcct gaaataaaat gctggatttg tttaaccaca
     1441 tccgcctgag ttagtgtcgc atatgcaact tgtttttcct gattaaaatc ataatctaag
     1501 gtcatttgaa tcatggagta atcagagtac acaacacttt caccattcaa aacaggttca
     1561 ttctttgtga tattggtctg acgaaattgc cccaccggaa tagagggttc aaatatatct
     1621 tgaaacaact ccttatgaat agcaagtaag gtcgcaggac taaagctaaa gcctcttcga
     1681 gacaatagtt ctacaatacg tagagaaacc aagtctgcct cttccgtact tgcatcaata
     1741 gtatggtgat aagccgttgc atcctcataa acctgctcat aagtcagttc tccccgggac
     1801 tgtttctcag ccaaagattc catatacgct gatggcacta gattgtcaac tttctgcaga
     1861 ccaaaaccta tccgccataa atcacgcttc gcttcataag acaagtttgg attgtcaatg
     1921 ttgtaagttg gttgcataga aatatccttt caattgtttt tcttcattac cagtaaatca
     1981 cgaaattggt tggaaactgg cttaaactat aaaaagtcct cacaataggt tctatgatat
     2041 atatatactt catgtaaata ataaaagagt tataatcagc actactgata aattcaatac
     2101 cgatttcgcc atcttaaaac ttagtcaaac gaataccgtt gatttccagt tcattaagtc
     2161 gttgacctgt caagacttct cgttccttca actggaaaag ttaaggggga actaatacaa
     2221 atcctctacg cttctatatt caatgatttc atttttgata atattctttt taaactcaaa
     2281 atgttttaaa ggattatcga ttaacactaa ctttggaata tcatctagat ttgtgaccaa
     2341 ggataaaata aaatccgatt gaaactcctt gactttttca aattcttttg cagttaaacg
     2401 cacacgcccc ttagattttc ggataccttt tacttcggca aggtaagaat actcttggac
     2461 atctacctga aagtcatatc catcaccata aagacgggca tcggttaact gtccaccttg
     2521 gaatttttct tctttatcaa aatgaaggat aaaataattc tcagcctcca ttcccgtttc
     2581 ctgtagacgt ttgaatttag ttcgaactat tggtttttca acgatggtta tgcctgtttt
     2641 cttcccttca ctggcaagta acattttaac tatttcagca taactatgaa catcttcatt
     2701 tccaaacatc atatcaatta aatctttacg aaaacgataa acttcagctt tctgccacca
     2761 accttttcga ttattgtcaa aataaggatc aaataaatcc attctatttt ttacaactcc
     2821 agttgtttca gcaattccca gagaaaccac atagcgataa aactccgact tgctagagca
     2881 ttgaaattct tttataaaaa gcttgtcaaa cttggcaaga ccgtagccaa ttaaatttaa
     2941 caattcataa tgagggtgtt tggacatcac tttctccatc aatagatatt gatttcatta
     3001 taccaaaaaa cacggctcat caccgtgttt ctgtgtttat ttcaccaact tcttcatctc
     3061 atcaatacgt gctacggtca catcatactt ggcttggtag tcggcttgtt tgtctttttc
     3121 tttttggaca acttctggtt tagcgttggc gacgaagcgt tcgttagaga gtttcttacc
     3181 aaccatgtcc agttcttttt gccatttagc gagttctttg tcgagacgag ctagttcttc
     3241 ttcaacattg aggagatcgg ccagtggcaa gaagatttcg gatcctgtaa taacgcttga
     3301 catagccagt tcaggtgcag ggatggttga tgcgatttcc aagtgttctg gatttgtaaa
     3361 gcgtttgata tagttgacat tgctgttaaa gaaggcttcc aagtcactat cgcttgtctt
     3421 aacaaggatg gtgataggct tgcttggtgc tacatttact tccgcacgcg cattccgaac
     3481 agcacgaatt aagtctttga gactttccac accagtgtga gccgcaaggt cttcaaaggc
     3541 tagattaaca gttgggtatg cagctgtcac gatagaacct tctgagattt gtccaaagat
     3601 ttcctctgtc acgaatggca tgattgggtg aaggagacga aggatcttgt ccaaagtgta
     3661 tagtagaaca gaacgtgtga tgactttctc ttcttcgtta tcgctataaa ggacttcctt
     3721 ggtcaactca acataccagt tggcaaattc ttcccaaatg aagttgtaaa ggatatgatc
     3781 agccacacca aactcgaact tatcaaagtt ttcagtaact tttgcaatgg tttcgttgag
     3841 attgtggaga atccagcggt ccgtcacatt accagcctca cctgttgcaa cttttgtgac
     3901 attgtcatgc gccacatcca gcgtcaaacc tccattgttc atgaggatat agcgagaaat
     3961 gttccaaatc ttgttaataa agttccatga agcatccatt ttctcataag agaaacgcac
     4021 gtcttgtcct ggcgcagaac cgtttgaaag gaaccatcga agggcatcgg caccgtattt
     4081 ctcgataaca tccattgggt caatcccgtt accgagagac ttagacatct tgcgtccttg
     4141 ctcgtcacga atgagaccgt ggataaggac gttttggaat ggttgacggc ctgtgaattc
     4201 caatgactgg aagatcatac gagacaccca gaagaagatg atgtcgtaac ctgttaccaa
     4261 ggttgaagtt gggaaataac gtttaaagtc ttctgagtcg acttcaggcc agcccatggt
     4321 tgaaaatggc cagagggcag aactgaacca agtatccaag acgtcttcgt cctgagtcca
     4381 tccgtcacct tctggagctt cttcgccgac atacatttca ccatcagcat tgtaccaggc
     4441 agggatttgg tgaccccacc aaagctgacg agagataacc cagtcgtgga cattttccat
     4501 ccattgaagg aaggtatcgt tgaaacgagg tgggtagaat tcgaccttgt cctctgtgtc
     4561 ttggttggca atggcgttct tagccaattg gtccatcttg acgaaccatt gagtagacaa
     4621 gcgtggctca actacgacac ctgtccgttc tgagtgaccg actgaatgga cacgtttttc
     4681 gattttgaca agggcaccga tttcttccaa cttagcaacg actgccttac gagcttcaaa
     4741 acgatccatg cctgaaaatt caaaggcaag ctcattcata gttccgtcgt cgttcatgac
     4801 gttgacttgt ggcaagttat gacgttggcc aaccaagaag tcatttggat cgtgggcagg
     4861 tgtgattttc acgacaccag taccaaactc aggatctgcg tgctcatctc caacgattgg
     4921 gatgagttta ttagcgattg gaaggatgac gtttttacca atcaagtcct tgtagcgcgg
     4981 gtcttctgga ttaaccgcaa ccgcaacgtc cccaaacata gtctcaggac gagttgtagc
     5041 aacttcaagg gcgcgtgaac catcttccag catgtaattc atgtggtaga aggcaccttc
     5101 tacatccttg tgaatcacct caatatcaga aagggctgtg cgagctgctg ggtcccagtt
     5161 gatgataaac tcaccacgat agatccagcc tttcttgtaa aggtccacaa agaccttacg
     5221 aacagctttt gacaaacctt cgtcaagagt gaaacgctca cgagaatagt ctacagaaag
     5281 ccccatcttg ccccattgtt ccttgatggt agtggcatat tcgtctttcc attcccagac
     5341 cttcgtcaag aaagactcac gacctaggtc ataacgcgta ataccctcac cacgtaagcg
     5401 ctcctcaacc ttagcctgag tcgcaatacc agcgtggtcc atacctggaa gccaaagggt
     5461 atcaaagccc tgcatgcgtt tttgacggat gatgatatcc tgcaaagtcg tatcccaagc
     5521 gtgaccaagg tgaagtttcc cagttacgtt tggtggtgga atcacgattg aataaggctt
     5581 agccttttga tcgcctgaag gcttgaaaac atccgcatca agccattttt ggtaacgacc
     5641 agcctcaacc tcggctggat tgtatttaga tgaaagttct ttagacatgt gtgttctcct
     5701 taattacttt tattgacaat tttaaccaaa ccaatttttg aaagttcaat ataaatctct
     5761 tcaatttcag caaatgctgc aagtggtgac atagtataat ttccaggatt atatttaaga
     5821 tcatact
//
LOCUS       DAVLUM010000094         5521 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLUM010000094 DAVLUM010000000
VERSION     DAVLUM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.094"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            4..1059
                     /locus_tag="VYN42_001886"
     CDS             4..1059
                     /locus_tag="VYN42_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1462915.1"
                     /translation="MKKYNIVDLFSGAGGLSYGFEMAGFNVLLGIDNDEKALETFQKN
                     HQNSEILCGDIANISYEEDIKPIIGEQKIDIIVGGPPCQGMSLSGPRRFDDPRNKLYL
                     SYIRLVREIQPTAFVIENVIGIVSLFKGQIKDTIIEEFSKMGYKVQFKVLLASDYGVP
                     QNRKRVIFVGTRNDGFEYPEALGTIITTEMAISDLPTLENELGEIEMSYVSEPQNDYQ
                     KLMRKRSNVVLNHVAAKHSEKVISTIALVPDGGNYKNLPKELRETRKFNVAWTRFASW
                     KPAPTIDTGHRHHFHYKYNRVPTVRESARLQSFPDDFIFYGSKTQQFRQVGNAVPPLM
                     AQQIANNLLKYLKNNEE"
     gene            1062..2462
                     /locus_tag="VYN42_001887"
     CDS             1062..2462
                     /locus_tag="VYN42_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1462916.1"
                     /translation="MYQVPEKYYFRLHHPRPRFKNDVENVLVYMATNISYLGILPKKE
                     FSQQLNDIIKQYAGNADKTEKTINNWRTEISSLFGMMIEKEGFVYSGNRAKELTEDQD
                     LIRFFKTFLYNFEYPGGHLKDNEIVKLCQIGVQFKPAQYLLELFTEASQAEEKTIYLT
                     DEEVAHCIFNDLRCTRDREPVLEIWNRIKENRASKVAYDTKGDVIRYAKDILDYMVIA
                     SLLTVQGGRYKINSMEEQAINDFLQSDATFDGYAQFIGNASTTIEGVRNFRSAWFEYV
                     NRDLGDIDFRTNFNLYLPSDIDFTEEKTDIIGHLTEHIEYSEKISTAVVGSSGEAIVI
                     NHEKQKLREHGQEQLLHLVNFIPTQFGVGYDVQSFECDDSELRKYIEVKTTVSNASIT
                     FNSFHITPNEWRTAKSVRDRYYIYRLQISKHSKKLFIIKNLYELVKNEKMLLIERKDG
                     YDVRFSSSVGFEENLI"
     gene            2459..3499
                     /gene="dcm"
                     /locus_tag="VYN42_001888"
     CDS             2459..3499
                     /gene="dcm"
                     /locus_tag="VYN42_001888"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEV1462917.1"
                     /translation="MKKLKIASLFSGGGGTDIGFAGGFDFLGKHYADNQIEIVYANDI
                     EDSANKMFEKNFGVTPDNRNIREIKSDEIPSFDILTGGFPCQSFSVSAQNPKRLGIKD
                     EKGTLFFEMVRVLKAHQPKAFFAENVKGILSANNKEAFPLIIEEFEKAGYNVSYKLCV
                     ATKYGVPQKRERVFIVGIRKDLNFTFEFPEEPIQNVEDYTPLKVILQQDIDEKYYFSE
                     RAVQGMLNSKSGKKMNKGRAQDIEQPSNTVSSHLAKVSLNSTDPVLLENGRYRRYTPR
                     EVARIQSFPENYELLGSEGAQYRMLGNAIPPVMMWYIAEKLVSDLRNSDVIAKQQKLE
                     ESFGQLDLFEAS"
     gene            3524..4318
                     /locus_tag="VYN42_001889"
     CDS             3524..4318
                     /locus_tag="VYN42_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEV1462918.1"
                     /translation="MELNFQDKSFIKVFFNSDGYVLNFSNSTFANFTFNSVGVNIQEK
                     YGGSKGKALQAFVDNEPDELVLKLALDLLRYYEDLPDSYYEKTEERNSQALKLKERLS
                     KYEVSQIAYLNNAAKSLSDYFDSDYIDKQMGIMNEMISRSPADAIGKAKELLESCFKH
                     ILDHEKIEYSNSNDIATLQKKVFKFLNLDSNENISAKNNQDVKVVLSGLNQIIKGINN
                     LRNDKGDGHGKGANFIELPPRYASVVVGSALTVVSFVWETYQDKQK"
     gene            4336..4899
                     /locus_tag="VYN42_001890"
     CDS             4336..4899
                     /locus_tag="VYN42_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HEV1462919.1"
                     /translation="MSKNQEKLHFQLKKFIVNVGWTHKIHAVRIDELESYIRWFRIAT
                     IIISGVVSSGLVGILWFDEYWIKLVTVFLSLVTTIIFSITKEFNFEERLALERKSVDE
                     LWNLRVLAEILLSEVVYNGKPSSEIQEFFEELKFRRDATYSQLSNASPKNVSKASKLI
                     KSRKDNDYEEDYRYFIPKELMEIKEEE"
     gene            4899..5521
                     /locus_tag="VYN42_001891"
                     /pseudo
     CDS             4899..5521
                     /locus_tag="VYN42_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
BASE COUNT         1918 a          762 c         1113 g         1728 t
ORIGIN      
        1 cagttgaaaa aatataacat tgtagattta ttttcaggag caggtggtct atcttatgga
       61 ttcgagatgg ctggatttaa tgttctatta ggaattgata atgacgaaaa agccttagaa
      121 acctttcaaa aaaatcatca gaattcagaa atattatgtg gagatattgc gaatatatct
      181 tatgaggaag atataaaacc aataattgga gaacaaaaaa ttgacataat tgtaggtggt
      241 cccccttgtc aggggatgtc gctttctgga cctagaagat ttgatgatcc aaggaacaaa
      301 ctttatttgt cttatattcg attggttcga gaaatacagc caactgcttt tgtcattgaa
      361 aatgtgattg ggattgttag tttgtttaaa gggcaaataa aagatactat tatagaagaa
      421 ttttcgaaaa tgggttataa ggttcagttt aaagtgttgc tggcctctga ctatggagtt
      481 cctcaaaata gaaaacgtgt tatttttgtg gggacgagga atgatggatt tgaatatcct
      541 gaagcattgg gaacaatcat tacaacagag atggcaattt ctgatttacc aacattagaa
      601 aatgaacttg gcgagataga aatgtcttat gtttcagaac cacaaaatga ctatcaaaaa
      661 ctaatgcgaa aacgttcaaa cgtagttttg aaccacgttg cagccaagca ttcagaaaaa
      721 gtgataagta caattgccct tgtccctgac ggtggaaatt ataaaaatct cccgaaggaa
      781 ttacgagaaa caagaaaatt taatgtcgct tggacacgat ttgctagttg gaagccagct
      841 cctacgattg atacggggca tagacatcat ttccactata agtataatcg tgtgccaaca
      901 gtgagggaat ctgctcgtct acaatctttt ccagatgatt ttatctttta cggaagtaaa
      961 acacagcaat ttagacaagt tggtaatgct gttcctcctt taatggctca gcagattgca
     1021 aacaatttac tgaaatattt aaaaaataac gaagagtaac tatgtatcaa gttccagaga
     1081 aatattattt tagactacat cacccaagac ctcgttttaa aaatgatgtc gaaaatgtac
     1141 ttgtttatat ggcaacgaat atttcttatt tgggaatatt gcctaaaaag gaatttagtc
     1201 agcaactaaa tgacattatc aaacaatatg caggaaatgc agataaaaca gagaaaacaa
     1261 tcaataattg gcgaacagag atttcttctt tgtttggaat gatgattgag aaagaaggct
     1321 ttgtctattc aggaaatagg gctaaggaat tgactgaaga ccaagacctt attcgctttt
     1381 ttaaaacctt tttgtataat tttgaatatc ctggtgggca tctaaaagat aacgagattg
     1441 ttaaactttg tcaaatcgga gttcaattta agccagctca gtatctactg gaactattta
     1501 cagaagcctc acaagctgaa gaaaaaacta tttacctcac cgatgaagaa gtcgcccatt
     1561 gtatctttaa tgatttgaga tgtactcgtg atagagagcc tgttttggaa atatggaatc
     1621 gtatcaaaga gaatagagcg tctaaagtag cttacgatac taaaggagat gttattcgat
     1681 atgccaaaga tattttagat tacatggtga tagcgagttt actaactgtt caaggtggta
     1741 ggtataaaat aaattctatg gaagagcaag caataaatga ctttttgcaa tcagatgcta
     1801 cctttgatgg ctatgctcaa tttattggaa atgcttctac aacaattgaa ggtgttcgaa
     1861 attttagaag tgcttggttc gaatatgtca atcgtgattt aggagatatt gattttagga
     1921 caaactttaa tctctacctt ccaagtgata ttgattttac tgaagagaaa acagatatta
     1981 tcggacatct aactgaacac atcgaataca gcgagaaaat atctaccgct gttgtaggga
     2041 gttcgggaga agctattgtt atcaatcatg aaaaacaaaa attacgagaa catgggcaag
     2101 aacagttgct ccatctggtg aattttattc caacacagtt tggtgtcggc tacgatgttc
     2161 aatcttttga gtgtgatgat tctgagctga gaaagtatat tgaagtcaaa acaactgtca
     2221 gcaatgcttc tattactttt aattcgtttc atatcacacc aaacgaatgg cgaactgcta
     2281 aatctgtgcg tgatagatac tatatttatc gtttgcagat ttctaaacat agcaaaaaat
     2341 tgtttattat caagaatttg tatgagttag tcaaaaatga gaagatgctt ctgattgaga
     2401 gaaaagatgg atatgatgtc cgtttttcat cgtcagttgg ctttgaggag aatttaattt
     2461 gaagaaacta aaaattgcct ctctttttag tggagggggt ggaacggata ttggttttgc
     2521 tggtggattt gattttttag gtaaacatta tgccgacaat caaattgaga ttgtctatgc
     2581 aaatgatatt gaagacagtg ccaataaaat gtttgaaaag aattttggtg ttactccaga
     2641 caatcgaaat atccgagaaa taaaatcaga tgaaatccca tctttcgata ttttaacggg
     2701 aggttttcct tgtcaatcat tttctgttag tgctcaaaat ccgaaacgct taggaataaa
     2761 agacgaaaaa gggacattgt tttttgagat ggtgcgagtg ttaaaagctc atcaaccaaa
     2821 agcatttttt gccgaaaatg ttaagggaat tttgtctgca aacaataaag aagcctttcc
     2881 tctaattatt gaagagttcg aaaaagctgg ttataatgtt tcttataaac tttgcgtagc
     2941 caccaaatac ggcgttccgc aaaagagaga gcgtgtgttt attgttggta ttcgaaagga
     3001 tttgaatttt acttttgaat ttcctgaaga gcctattcaa aatgtagaag attatacacc
     3061 actaaaagta attcttcagc aagatattga tgaaaagtat tattttagtg agagggctgt
     3121 gcaaggaatg ctaaatagta aatctggcaa aaaaatgaat aaaggacgag cacaagacat
     3181 tgaacagccg agtaatacgg ttagttctca cttagcaaaa gtatccttaa atagcactga
     3241 ccctgttttg ttagaaaatg gacgttaccg tcgctatact ccaagagagg ttgcacgtat
     3301 tcagtcgttt ccagaaaact atgaattgct tggttcagaa ggtgctcaat atagaatgct
     3361 ggggaatgct attccaccag taatgatgtg gtatattgct gaaaagttag tgtcagattt
     3421 acgaaatagt gatgtaattg caaagcaaca gaaactcgaa gaaagttttg gtcaactgga
     3481 tttgtttgaa gcgagttgat gttttaaatc tagggaactt gatatggaat taaattttca
     3541 agataagagt tttataaaag tattttttaa tagtgacggt tatgtattaa atttttctaa
     3601 ctctactttt gctaatttta cttttaattc agtaggagta aatattcaag agaaatatgg
     3661 aggttcaaaa gggaaagctt tacaggcttt tgtagataac gaaccagatg aactggtttt
     3721 aaaattggct ttagatttac ttagatatta tgaagacctt cctgactcat attacgagaa
     3781 aactgaagag aggaactctc aggcattgaa attgaaagag agactttcga aatatgaagt
     3841 ctcacaaata gcctacttaa ataatgctgc taaatcttta tctgactatt ttgatagcga
     3901 ctatatagat aagcaaatgg ggattatgaa tgaaatgatt tctcgctctc cagcggacgc
     3961 tattggaaaa gctaaggaat tgttggaatc gtgttttaaa catattttag accatgaaaa
     4021 aattgagtat tctaattcta atgatattgc aactttgcaa aagaaagtct ttaaattttt
     4081 aaacttggat tctaatgaaa atatttcagc aaaaaataat caagatgtga aggtggttct
     4141 aagtggtttg aatcaaatta tcaagggtat taacaatctt agaaatgata aaggtgatgg
     4201 tcatggtaag ggagctaact ttatagaatt gccaccaagg tatgcttcag ttgttgtagg
     4261 ttctgcatta acggtagtgt catttgtttg ggaaacatac caagataagc aaaaatagta
     4321 aaggagggag atttaatgtc gaaaaatcaa gaaaaattac actttcaact taaaaaattt
     4381 atagtaaatg taggttggac tcacaaaatt catgcggtta gaattgacga gttagaaagc
     4441 tatattcgat ggtttagaat agcaacaata atcatttctg gagttgtctc ttctggctta
     4501 gttggaatac tttggtttga tgaatattgg ataaagcttg ttacagtatt tttatcatta
     4561 gtcacgacaa taatttttag catcacaaag gagtttaact ttgaggaacg actagctttg
     4621 gagaggaaat ctgttgatga gctttggaat cttagagtgt tagctgaaat tcttttatct
     4681 gaggtggttt acaatggaaa accatccagt gaaatccaag aatttttcga agaattaaaa
     4741 tttcgaagag atgctactta tagtcaactt tctaatgctt ctcccaaaaa tgtatccaag
     4801 gcttcaaaac taataaaatc gagaaaagat aatgattatg aggaggatta tagatacttt
     4861 attccaaaag aattgatgga aattaaggag gaagagtaat gtctttatct aatgatttta
     4921 aagaattttg cgaagacgaa ctccccatga cggatgagga atgggaaaaa tgggagaata
     4981 gattaaaaga gattacgaaa cgacttaatc gaaaatttta ttccttagat gagcttgacg
     5041 atcaagaaac tgacaacggt ttgattgttg gtagtgtggg gagaacgacg gctgttcgaa
     5101 atgttagtga ttttgattat attttttctc taccatcaga agtgtataga tgatttgatt
     5161 cttatgaggg caatggtcaa tcagcactcc tacaggaaat aaaaaacgaa ttactaaaaa
     5221 gatacccaaa tacaaaaata aaaggagacg gacaggtcgt tgttattgat ttttcggatg
     5281 gtggaaaaat tgagttagtt ccagctttcg aaaaatctga tggtaatttt aaatatcctg
     5341 attctcgtaa cggaggttct tggaaaacta ctaaaccaaa gtctgaaatt gaaaaatgca
     5401 aatctttaaa ttccaatttt aatagtcatt tttctaactt aacaaggctc atacgacaat
     5461 ggaaaaatca tatgggcttt tcatttaagg ggttgttgat agatactttg atatctgatt
     5521 t
//
LOCUS       DAVLUM010000095         5326 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLUM010000095 DAVLUM010000000
VERSION     DAVLUM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.095"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     misc_feature    76..211
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            250..750
                     /locus_tag="VYN42_001892"
     CDS             250..750
                     /locus_tag="VYN42_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1462920.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNNFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            826..1194
                     /gene="rplL"
                     /locus_tag="VYN42_001893"
     CDS             826..1194
                     /gene="rplL"
                     /locus_tag="VYN42_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1462921.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            1381..1551
                     /locus_tag="VYN42_001894"
     CDS             1381..1551
                     /locus_tag="VYN42_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462922.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            1551..1802
                     /locus_tag="VYN42_001895"
                     /pseudo
     CDS             1551..1802
                     /locus_tag="VYN42_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            1789..2136
                     /locus_tag="VYN42_001896"
                     /pseudo
     CDS             1789..2136
                     /locus_tag="VYN42_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2129..2509
                     /locus_tag="VYN42_001897"
     CDS             2129..2509
                     /locus_tag="VYN42_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462923.1"
                     /translation="MIDLYLSKNSRRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLKLTDFIEMILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            2522..2665
                     /locus_tag="VYN42_001898"
     CDS             2522..2665
                     /locus_tag="VYN42_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462924.1"
                     /translation="MAERFWKNLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            2758..3345
                     /locus_tag="VYN42_001899"
     CDS             2758..3345
                     /locus_tag="VYN42_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462925.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            3547..3684
                     /locus_tag="VYN42_001900"
     CDS             3547..3684
                     /locus_tag="VYN42_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1462926.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            3980..>5326
                     /locus_tag="VYN42_001901"
     CDS             join(3980..4421,4421..>5326)
                     /locus_tag="VYN42_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1462927.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSF"
BASE COUNT         1750 a          835 c         1130 g         1611 t
ORIGIN      
        1 aagaaaaatt acgaaaaatt ttaaaaaaag tttgcaaaaa tcttgcattc tttttttgac
       61 tatgctatac ttatatacgg tttaaaaaaa ctgcctaaga cagtagggga gctcgactca
      121 taaatatcct accgaggaca agacgtatca tgtaaaaaga agcgtattgt actttcgtgt
      181 ctaggtttgg gcgcgttttt ctttttgaaa aattccccaa gcaaaataat tacggaggtg
      241 aacacactaa tgagtgaagc aattattgct aaaaaagcgg aactagttga cgtagtagct
      301 gaaaaaatga aagctgctgc atctatcgtc gttgtagacg ctcgtggttt gacagttgag
      361 caagatacag ttcttcgtcg tgagcttcgt ggaagcgaag ttgagtataa agttattaaa
      421 aactcaatct tgcgtcgtgc agctgaaaaa gctggtcttg aagatcttgc atctgtattt
      481 gttggaccat ctgcagtagc attttctaat gaagatgtta tcgcaccagc gaaaatcttg
      541 aacaactttt ctaaaaacgc tgaagcactt gaaattaaag gtggtgcaat cgaaggcgct
      601 gtcgcatcta aagaagagat tcttgcactt gcaactcttc caaaccgcga aggacttctt
      661 tctatgctcc tttctgtact tcaagcgcca gtgcgcaacg ttgctcttgc agtcaaagcg
      721 gttgcagaaa gcaaagaaga cgcggcttaa tcttaagcta cacagcgtag cctagctacg
      781 aaaaaaacta ttataaaatt taaaacttat ttggaggaaa taacaatggc attgaacatt
      841 gaaaacatta ttgctgaaat taaagaagct tcaatccttg aattgaacga ccttgtaaaa
      901 gctatcgaag aagaatttgg tgtaactgca gctgctcctg tagctgttgc tgcagctgat
      961 gctgctgatg ctggtgctgc taaagattca ttcgacgttg aattgacatc tgcaggcgac
     1021 aaaaaagttg gcgttatcaa agttgtacgt gaaatcactg gtcttggtct taaagaagct
     1081 aaagaacttg ttgacggtgc accagcactt gttaaagaag gcgttgcaac tgcagaagct
     1141 gaagaaatca aagctaaatt ggaagaagct ggagcttcag ttactcttaa ataatagagt
     1201 atcgcaattt gattgcggaa tccctattta ccagtctttg agagcgataa gcgattgata
     1261 gaaactgata aattgatttg gtttcctgcc aaaaattctt tggcaggatt tttgttttaa
     1321 taaactttcg ggggtagaca ctagattgtc tacccctttt tttgtgtttc ggaggtaatt
     1381 atgcaaaagg aaggacagtc atcacgtcaa ttcgtgaaga gtcatctcat gactatcatg
     1441 ggagttgata ttgtaaaagc aactcagtta gttgatgaaa tggaacaagt aggtttaatc
     1501 cgatttgatg aatttggaaa tgttggaatt ttagtcttgg agggacaata atgaagcgta
     1561 ttaccgctaa tcaatatcag acatcagagc gttattataa gctccccaaa cttttatttg
     1621 agagtgaacg gtataagaat atgaaactgg aggttaaggt ggtttactca gttttaaaag
     1681 atcggttgga gttgtctttg agcaaaggtt ggattgatga ggatggggct atttatttga
     1741 tttattccaa ttcaaatttg atggcacttt taggctgttc aaagtcaaaa ttactctcca
     1801 tgtgagtttg aagtaacatt tttagatgat taccataaaa aacacaacta cccactattt
     1861 tacgaatcct atcttcaaaa cgttatggaa ttccttgaaa gtcaagacat aaagaatggg
     1921 gttgatgcct ttgtagatga tcatcaaaat ctcgtttttg ttttatatgg acaaggctat
     1981 cgagccgagg gaaaagaggg aatacttaca acccaagtaa ctgtaaaagc ttatgatgaa
     2041 gacaagaaac cgattaactt cgcaaattta ttagattcct taatcgtctc agaatatcaa
     2101 atggaaccga atctttggga ggtctcctat gattgatctc tatctaagta aaaatagccg
     2161 aagaaatcaa cttcttttag acttcttcca aaactatggc atcgaggtat cttgtcattc
     2221 agtttctgaa atgacaaagg acaaattaat tgagatgatg agctattctt cagattgttt
     2281 tgagttttta tctccaaatt tattacgttt taagaatcga gataacctaa aattaacaga
     2341 tttcatcgaa atgatattaa aaaatcctga actaaccatc agacttcctc ttgcggtttc
     2401 aaataagcga gtttatccaa gtctgaattt ggaagaggct agagctctat tgccaagaga
     2461 tacgaaacaa ttgatttaca tggcgcaaac acattattta tctaactaaa ggagaagcaa
     2521 tatggctgaa cgattttgga agaacttgtc cattattttg gctgaaagaa atatcagctg
     2581 gattgagtta accagaaaaa tgtttgcggg agagtttcac tatccaagtg aattgaatcg
     2641 tttgtatcaa aagattcgcc actagaagat ggaacaacga atgcctcaaa gttcatgggt
     2701 agaaaggatt gtgcaggtat tagatttaga ttatgaagat ttatttcgga ggtaactatg
     2761 aaaagaataa ttccagttta tatattccaa caagtaaatg tcctattggt atctctatac
     2821 ttattgaaat ttctttgtat cggtgagtta accatactac agattctcta tggttcgtca
     2881 ctcatttctt ttttatggat gtatggccaa cgcaaacaag cgcataaggt caatatgaaa
     2941 tctaggatga aatggcttgg tgttgaattt gttagcctac tgattataag tctatgtttt
     3001 agtctgattc atgctcaagg aagcacgaat caagcaaact taattggcct tcaacatcaa
     3061 attccttggt tttcattttt attgttctta atcaatgcga gtatggttga agaatttctg
     3121 tatcgagaaa ttttatggaa tttggtcaga aaattagata tcagagttgc tttgacaagt
     3181 gttttatttg ccttagcaca tcatacagga accattctag cttggtgttt gtatgtttca
     3241 cttgggatgt ttttaggtat ggtgcgctat aaatctgact tatggggcag tatgggacta
     3301 catttggtgt ggaacctact agtttatagt ttgctgcttt tttaaaatag gtgacctgat
     3361 ttttaggtaa cttctaaaac taacttccag ttttgggaga gagatggaag ttactttgaa
     3421 aagttacgga aacattattt tctatgtgac aacattgtat aattgcttgc attttactgg
     3481 tggagagagt ataatgaggg tggataaagt acttaatccc aaaaatttaa ataggaggag
     3541 ctagctatgg cagaagaagt attaaatctt caattagtat ctgttcaagt tgacgaaaca
     3601 gatgaagttg atggaatgcg atttagtaca ttcagtacaa accgttgcgg taactggagt
     3661 gcttttagtt gggaaaattg ttaattcatt taaattgtaa actttaggga ttctctgaag
     3721 ttatggatgt cgttccaata tgtgtacgtt ggaatgttag tgcttatatg gggggaacag
     3781 aatcctctct tgattgaaga caagttagcc attaggctgg tttgtctctt tgtcaactgt
     3841 agtgggttga tataatagta ttagtgagtg ggataaaagt ttcatttagt ttattcagta
     3901 caaatttaac gggtcaagat ttattgaact gcaccccaat agttagacag aaaaaatcta
     3961 acttttgggg tgttttatta tgaaattgag ttatgaagat aaagttcaga tctatgaact
     4021 aagaaagcaa ggacaaagct tcaaacagct ttcaaaaaga tttggtgtgg atgtttctgg
     4081 tctaaagtac atggtgaaat taattgaccg ttatggcata gaaatcgtta aaaaagggaa
     4141 gaatcgtcac tattcttcta aattgaaaca agaaatgatg gataaagcct tactggaagg
     4201 ttgttcacaa agaagtatta gtcttgatta tgccctccca aaccaaggaa tgctttcatt
     4261 ttggccggca caatacaaga aaaacgggta tactattgtt gagaaaacaa gagggagacc
     4321 agctaaaatg ggacgtaaac ggaagaagac ttgggaagaa atgacagaac tagaacgact
     4381 ccaggaggag aatgaacgct tacggactga ggtggcctac ctaaaaaagt taaaagagtt
     4441 agaggaaagg gacgaagccc tagagcgaga aaggcagaga cagttagaga aatggtttca
     4501 ggaggatttc gactagattt tcttcttgaa acagcacgtt tagctcgctc gacttactat
     4561 tatcagttga aacaactgga tggggttgat aaagataaag agattaaaac cgaaattcag
     4621 ggcattgata atgaacataa aggcaactat ggctatcgtc gaatccattt agaactaagg
     4681 aatcgtggtt ttgtggtcaa tcataagaaa gttcaacggt tgatgagaat tcttggttta
     4741 acggctcgaa ttcgccgtaa acggaagtat tcttcctacc aaggagagat tggcaagaaa
     4801 gcagagaatc tcattcaacg ccagttcgaa gcatcgaggc caatggaaaa gtgctataca
     4861 gatgtgacag agtttgccat tccaaatagc acacagaaac tctatttatc accagtttta
     4921 gatggtttta acagtgaaat cattgcttat catctttcta cttcgccaaa cttagaacaa
     4981 gtgaagagta tgttagaaca ggcctttaca gagaaatact atgagaatac gattctccat
     5041 agtgaccaag gctggcaata ccaacacgat tcttatcatc ggttcctaga gagtaaggaa
     5101 attcaagcat ccatgtcacg caagggcaac agcccagaca acggcatgat ggaatctttc
     5161 tttggcattt taaaatccga aatgttttat ggctatgaga agaactttag atctttagaa
     5221 aaccttgaac aagctattgt ggactacatt gattactaca acaacaaacg aattaaggta
     5281 aaactaaaag gacttagttc tgtgcagtac agaactaaat cctttg
//
LOCUS       DAVLUM010000096         5028 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLUM010000096 DAVLUM010000000
VERSION     DAVLUM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.096"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(359..1087)
                     /locus_tag="VYN42_001902"
     CDS             complement(359..1087)
                     /locus_tag="VYN42_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1462928.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1245..2654
                     /locus_tag="VYN42_001903"
     CDS             1245..2654
                     /locus_tag="VYN42_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1462929.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2672..3967
                     /locus_tag="VYN42_001904"
     CDS             2672..3967
                     /locus_tag="VYN42_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1462930.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3972..4280
                     /locus_tag="VYN42_001905"
     CDS             3972..4280
                     /locus_tag="VYN42_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1462931.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4277..4585
                     /locus_tag="VYN42_001906"
     CDS             4277..4585
                     /locus_tag="VYN42_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1462932.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1699 a          844 c          919 g         1566 t
ORIGIN      
        1 gggagattga aattcatttc tagcaatttt ttagaagtca cagtctacta ttctaacctc
       61 aatatactat atgtgttaca agaaaagact caaaaacttc tcgtcagtgt aagaatgttt
      121 gaaacactat ttaaaactaa ataactataa gaagtatatc aggtgaacaa tttcagtacc
      181 tactctataa gctatacgaa gatatttttc aacatgatgg ataaaacgat cactctttta
      241 aagtcatctt atttagaaaa gagaaaccat ttaagcatag atgggacctt cttgccctgt
      301 tttaaatttt tcttaaacta gagcctgtaa aagattggct tcattttcac attttctcct
      361 aggaggaatg tcgtaatgca aaagaattaa attcaaataa atcatagcga tgacgactaa
      421 tcgagtactc aaacggagtt ccattatcca aataagccac ttgttctact tcaaataccg
      481 gttccgttgg aaggagctgc aagtaatgtt gctcattttc tgaactagaa gaagctcgta
      541 agatttttgt agcactggca atatgcaatc ctaactttcc ttcaatgtaa ttgtaaatcg
      601 atttttgtaa aatatcttca gtaatacctg gaataacatc ggtactcata taagtttgtt
      661 ccagaacata aggtttaccg tcaataatac gcaggcggta aatattataa actggactct
      721 gcaaagcgac ctgtagtttt tctgctaaaa attcatttgc aaattctaat ttgaagtgaa
      781 taatcctcga gtcaattgta gaatgagcat cttcagatat ttttgtcagt ccccggatat
      841 ctctttctgg aacgattaat tttctttttg agctgccacg agagagaaca aaggttccct
      901 gcccacgttt tctaaaaatt aagccctcag aaactaacaa gtctaaagct tttttgatcg
      961 tcattcgact acaggcaaac tgtttagcta atgtcatttc atcaggcaat tgttcgttca
     1021 tggtatattt attacaaaga atcttttcac gaatctcatt gtaaataaat aaatattttg
     1081 tactcattta atctggttct ctctataata ttctaatagt agtataacaa agttcaagaa
     1141 atgaggcaaa cacaagatat gtatcaacaa tttttaaaaa tgtctagaca aattttaaag
     1201 ttatgctata ctttatgtat agaataatag aaaggaggtt gagcatgaaa aaaaagttag
     1261 tatttcctaa tctgttttgg tggggagctg cttctagcgg acctcagaca gaaggtcaat
     1321 atggaaaagt acatgaaaat gtgatggact actggttcaa aacgcatcca gaagattttt
     1381 tcgataatgt cggacctctt gtagccagta acttttttca tacttacacc gaagatttcc
     1441 acttgatgaa ggaaattgga gttaattctt tccgcacttc catccaatgg agtcgactca
     1501 tcaagaattt agagacaggt gagcctgatc caaaaggtat tgctttctac aatgccatca
     1561 ttgaagaagc taaaaagaac cagatggatc ttgtgatgaa tttacatcat tttgatttac
     1621 cagtggaact tcttcaaaaa tacggtggtt gggaaagcaa acatgtagtg gagttattcg
     1681 tgaagtttgc caagactgct ttcacatgct ttggagataa ggttcattac tggacaactt
     1741 tcaatgagcc aatggtcatt ccagaagcag gatacttata tgctttccat tatccaaatc
     1801 taaaaggaaa gggaaaagag gccgtacaag tcatctataa tctaaacctt gctagtgcaa
     1861 aagtgattca actatatcgc tcattaggac ttgatggaaa gattgggatt attttaaact
     1921 tgacacctgc ttatccaaga agtaattctc cagaagactt agaagcaagt cgatttacag
     1981 atgacttctt taacaaagtc ttcttgaatc cagctgttaa aggaactttc ccagaaagat
     2041 tggtaaaaca gctagagaga gatggcgtgt tatggagtca taccgaaaaa gagcttcaac
     2101 tgatgaaatc aaatacggtt gattttcttg gagtaaacta ctaccatcca aaacgtgttc
     2161 aagcacaagc aaatcctgag gaatatcaga cgccctggat gccagaccaa tacttcaaag
     2221 agtatgaatg gccggagcgt cgcatgaatc catatcgtgg ttgggaaatt tttccgaaag
     2281 ccatttatga tattgctatg attgtgaagg aagaatatga taatattcca tggtttatca
     2341 gtgaaaacgg aatgggtgtt gaaaacgaag cacggtttat cggtgaaaat ggagttatcg
     2401 atgacgtgta tcgtattgaa ttttatgaag aacatttaag atggctacat aaagccattg
     2461 aagagggaag tcactgtttt ggataccacg cttggaccgc atttgattgc tggtcttgga
     2521 ataatgcata taagaatcgt tacggattta tctccgttga tttagaaacg caaaagagaa
     2581 ccatcaagag ctcaggaaga tggtatcgca aagtaagtga caataacggt tttgaagtag
     2641 aaattgagga gtaaagagag gagatattca gatgaaaaac tcaaaattta tagatcaatt
     2701 tgccaccttt gctggtaaac tagggaacca aattcattta aaaaccctaa gagatgcatt
     2761 cgtaacagta atgccattat atattttggc aggtttaatc gttcttttga acaacacggt
     2821 atttaagtgg attttccaag gggatacatt aacaagattc caatattggg gaataacaat
     2881 tgcaaacggt actttaagta tttcaggtat gattattgct gtaatggttg gttatttctt
     2941 agctaaaaac agagatttcg aaaacccgtt agcagcatca atgctatcat tagtttcttt
     3001 aattgtgatg atgccaaata cagtttctgt agttcctgac ggagcaaaag atgcggtaaa
     3061 catttcaggt gttctttcat tcaacaacac aggtacaggc gcaatgttcg ccggggttat
     3121 cgtagcgatt attgcaacag aattattcat tgaattatca aacgttaaag ctttacaaat
     3181 gaaccttggt gaaaatattc caccagctgt tagtagatca tttagcgtat tacttccagt
     3241 catgactgtc atctccttat ttgggattgt ttcagcatta ttattcaata taactggaat
     3301 gaacttaatc tcaatcatta caatctttat tcaagaacca attcgtcata ttggtacaag
     3361 cttaatcggg gtcattatta tttactcttt aggaaatatg ttatggctat ttggtattca
     3421 ccaagcagtt atttacagtg ccatcttaga accattacta ttaattaaca ttactgaaaa
     3481 catcactgca gcaaataatg gacaagccat tccacacatc atcaacttat cacaaataca
     3541 aacattcgct ttaatgggtg gtagtggatc tacattatgt ttattaatag caacattctt
     3601 agtgagtcgc aatgctgtct ctaaaaacgt ggctaaatta tcttttggac ctggtatctt
     3661 caatatcaat gaaccagtat tattcggtta cccaatcgtt tataacattt cattagctat
     3721 tccatttatc acagttccag tccttggtat tttaatcagc tacttagcaa cagttacagg
     3781 attcatgagt cctgcattta tacaagttcc ttggactaca ccagtattct taaatgcatg
     3841 gttagcaaca gcaggggacg tgagagcagt tctagttcaa ttcatcatct ttgcacttgg
     3901 agttcttcta tacattccat ttatcaaagt taatgacaaa gttgttgaac aagaaatgga
     3961 aggttaagat tatgaaacaa attttattag tatgtaatgc gggaatgtcg acaagtatgc
     4021 ttgttaaaaa aatgcaacaa agtgcgactg aacgtgggat tgaaatttct atccaagcaa
     4081 aatcaatgac agaagcgaaa aagaatatcc atgaagcaga tgtcattcta attgggccac
     4141 aaattcgtta tgagttactt gctgtgaaag aaattgcagg aaatatccct gtagatacca
     4201 ttgatatgcg ggattacgga atgatgaatg gagcaaaagt tctggaacaa gcacttgcat
     4261 ggataggaga aataagatga cagaagaaat ggaatatatc tgttttcagc tcattgccaa
     4321 tagtggagca gccaaatcat cctttattga agccatccaa ctagctaagg caggaaattt
     4381 aaaagaagcg aaaattaaag ttgaagaagc ggaagactcc ttagtagaag tgcacaagat
     4441 tcactctaat ctcatacaaa aagaagctac tggagaaaaa ataggattct ccttgctatt
     4501 tatgcatgca gaagaccaaa tggcttcaac ggagattatt cagttgctat ctaaagaatt
     4561 catcgatctc tatcaaaata aataggaaca ctgtcgttcc catctgtctt tattaatgac
     4621 ggctacattg taggaacctc caaaagttgg acaaaatgat tgaaaggatt ggatcctgca
     4681 ttacacaaga tccaatcctt ttcttttact ctagttttta taatatgttg aatctagaat
     4741 agtccactgt agtttctaaa aaattgctgg aaatggatgt taagctccaa tttatttgtt
     4801 tatatcttat ttcagtttac tatactagct tattattcta gtgaaaaatt gaatgagcca
     4861 ctatttattt aatatgtatg atgagggaat gactcaaaaa cttcttgtcg atataagaat
     4921 atctgagata gtattttaaa acgaaaggat tataaaagct catttccttc gcacttattt
     4981 tatagagatc tatcattata ctctttagaa atcaaaaagc aacacacc
//
LOCUS       DAVLUM010000097         4942 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLUM010000097 DAVLUM010000000
VERSION     DAVLUM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4942
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.097"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            322..1194
                     /locus_tag="VYN42_001907"
     CDS             322..1194
                     /locus_tag="VYN42_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1462933.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            1207..1371
                     /locus_tag="VYN42_001908"
     CDS             1207..1371
                     /locus_tag="VYN42_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462934.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(1340..1684)
                     /locus_tag="VYN42_001909"
                     /pseudo
     CDS             complement(1340..1684)
                     /locus_tag="VYN42_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1827..2138
                     /locus_tag="VYN42_001910"
     CDS             1827..2138
                     /locus_tag="VYN42_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462935.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            2142..2858
                     /locus_tag="VYN42_001911"
     CDS             2142..2858
                     /locus_tag="VYN42_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1462936.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(2988..3803)
                     /locus_tag="VYN42_001912"
     CDS             complement(2988..3803)
                     /locus_tag="VYN42_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1462937.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(3800..4705)
                     /locus_tag="VYN42_001913"
     CDS             complement(3800..4705)
                     /locus_tag="VYN42_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1462938.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
BASE COUNT         1649 a          852 c         1000 g         1441 t
ORIGIN      
        1 agttgttcat atcttatttc aatctattat gtttttcacc tctaacaatc gcaatctctt
       61 ctttatccat gaatgaaatc gctttctatt tttgtaagta aagcataaca cgaaatccac
      121 gaaaatgaaa acctttgttg tgttttcgta aaaaatttgt tgacagagca cgaaacgcct
      181 actataatta aatcaagttt aaggaaataa caaaaaaaca aatcggaggg aaagacgatg
      241 aacacattaa atgagaaagt aatcaatatc tgtaaagcag tagttaaaga aactttaatc
      301 caagacattt aggagaaaga aatgaagaaa tcaagaaaat tagccacatt aggaatctgt
      361 tcagccttgt ttttaggctt ggctgcttgt caacaacaac atgctacttc tgaggggacg
      421 aatcaaaggc aaagcagttc agcgaaagtt ccatggaaag cttcatacac caacctaaac
      481 aaccaggtaa gtacagaaga ggtcaaatct ctcttatcag ctcacttgga tccaaatagt
      541 gttgatgcat tttttaatct cgttaatgac tataatacca ttgtcggctc aactggctta
      601 tcaggagatt tcacttcctt tactcacacc gaatacgatg ttgagaaaat cagtcatctc
      661 tggaatcaaa agaagggcga tttcgttggg accaactgcc gtatcaatag ttattgtctt
      721 ttgaaaaatt cagtcaccat tccaaagctt gaaaagaatg accaattgct tttcctagat
      781 aatgatgcga ttgataaagg aaaggtcttt gattcacaag ataaggaaga gtttgatatt
      841 ctattttcga gagttccaac tgaggcaact acagatgtca aggttcacgc tgaaaagatg
      901 gaaacattct tctcacaatt tcaattcaat gaaaaagctc gaatgctgtc tgtagtcttg
      961 cacgacaatt tggatggcga gtatctgttt gtaggccacg ttggggtctt agtacctgct
     1021 gatgacggtt tcttatttgt agagaaattg actttcgaag agccctacca agcgattaaa
     1081 tttgctagta aggaagattg ctacaagtat ttgggcacca agtatgcgga ttatacaggc
     1141 gagggactgg ctaagccttt tatcatggat aatgataagt gggttaaact ttaatagtgt
     1201 tatgatatga cagtaatctt aggattttta tttctatttt tgatgacttg gtgggttatt
     1261 tcaatcgtta atagccagaa accactcaaa aatgaaacat ttattggcta tgtccaaaga
     1321 tacgatattg atgggaatgg ctatcaatca ttaccgtgtc ctcagaactg agaggagttc
     1381 ttgaaatcgt aacaccactt tgaacaagag ttacttcaac ccattggctc cgccggagta
     1441 agttgctttc gtgaacacca aaatcagccg caatttcttc ataagtgcgg tattctcaca
     1501 catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt cgtccacctt
     1561 ttgcgtgttt aagttgataa gctgttttta atacagctaa catctcttca aaagtggtac
     1621 gctgaacacc aacaagacgc ttaaatcgtg catcagttag ttgtttactt gcttcatcat
     1681 tcatagaact actataccat attttgtttc gcaggaagtc taatgctaaa atcttatcag
     1741 tgagaagatt tcttaaagtt tattctttgt agtttcatct gtattagtac ataatttaac
     1801 ttagagaaaa taggaggact aatcgaatgg aattaaaaga ttttacagaa aaagaacagg
     1861 aaatgattaa gaaaaggctt acaatgtcta atattagtga caaagaaact actgagaaga
     1921 ttctggcgct agtaccacaa gacttgatta agcgaatccc gttttttgtc agaaaacatg
     1981 ctacaacacg tacgattaaa cgcatttcaa ttgaataccc tgaactctac gctgtagctc
     2041 aaacaagtgg tgagattcca gaaaaagaac gcgaagaatt gcgtcagatt atcacaacta
     2101 tctttgaaca aaagatgaat aagcatagta ttaagtagag aatgaaaaaa tattttatta
     2161 gcggtttggg aagcaatgcc tatcatagca aggatttttt tcaagaacta gattcgcagg
     2221 tctattttct aaatccatat gaaaagcatc ttcgagatga aacagaattg aaatcatggt
     2281 ttaaaaatga gattgtagag gaagaatcta tctgtctgat aggccattct cttggaggag
     2341 atttagctcg ttatttcgca tcggaatttg aagaagtaaa gaaactgatt cttttggatg
     2401 gtggctatct agatttagat aagattttac ctttggatac agagttagag gaaactaaaa
     2461 attatatcaa atctcaaatt gtttcggact tagctcttct tatttctaaa gagaagtccg
     2521 aagcaaagca ttggtcagaa aatatggaga aagctgtaag acagtcctat cactggaatg
     2581 ttgagtataa tagatatgag ttggctataa attatgaaaa tatagaagcg atactccgcc
     2641 tacggagaaa aatacaagct tttaagagag aagtgggaga taccttgttt attagtcctc
     2701 gctatcctaa tggagctaca tggagagagg aagccctaaa agaattgcca gactatttta
     2761 atactatttt tttagaaaac tttggccatg agctttatac tcaagcacct aaagaaatcg
     2821 ctagtctaat gaatgagtgg ctcgcttatt ttctatgagc tacttgtatt gctggaaatg
     2881 gtataagatg aaaatctaca agtcactaat tttcatataa caaaaaaacg aacaggctct
     2941 ttttctgtta ttcagaagag aacttgttcg tttttatctt gattttctta aaaagctcta
     3001 tatacatagg gattttctgg tttatcgact ttggtaaagc tgtcgatttc caaggttgga
     3061 aggttttgtt tgagttcttt atggtagtga ttgaccagtt ttcctttggc tgtaatccag
     3121 gtgttgtttt catactgccg ggtattgccc ttggtcagca atccatagac accagaatct
     3181 gcgatacagt ggataatgcc gaatcggaac agaaattgac tattggcatg actggggtcg
     3241 ttatagacaa agcctgtaaa ctggattgtc ttgccctcaa attcatctgg atagtcgtag
     3301 atagcctcca tgacttccat atagttttca ttagtgatct gaatactatc ttgggataag
     3361 tatttatccg ccgccgttcg catttccttt tcataggctg attttgaaaa ataagaacta
     3421 gtatctggtt tcaaatattg gcttgtcgtc ccttcacttg tctgaatagc tagatccgtt
     3481 ccttccgata gggggaaatg ataaccttta gcagaaacgg tctgagaatc caagctaaca
     3541 gttgggaaag ttaagccgat gacaagtgga atagccagaa gagaaatact cgtcatcttg
     3601 gccaatcggc tgttcagatg actgtgggtt ttgacttgct tcatccagat atacaattga
     3661 acaattgcca agataaagga aagcaccatg gagatatagg ccagatagga atagtgcatg
     3721 ttgatgtact ggtttagttt gcccgacaga tggaggtaaa tagtcagttc aaaatagcca
     3781 gctaaaacta aaaatcgaat cataggatga ctccaatcaa gagagaatag gctaaaacga
     3841 ccagagtcac aatcgtaatg aagtgactaa taaatcgtgc tttcaagtaa tttttcatca
     3901 tgagaatatt tttgatatcc agcattgggc caatgacgag aaaggccaga actggtgcca
     3961 aaccgaaact cgagagtaga gaagcaccta taaaggcatc cgcctcacta cagagcgaaa
     4021 gaagaaaggc taaaagcatc aagagcagga tagcaaaaag aggagtcgca ctgatagagg
     4081 tcagaatccg agtcggaacg tagacctgta ttatagaagc aaagaggcag ccaaatacca
     4141 aataacgccc cgtatcaaaa aattcatcaa tggcctgcac aaagacttga aaaacttttt
     4201 ttgcagaact caagtaagaa aaatcatgct catgacaagc cagacgattt tctttctgaa
     4261 tcggttcttg ccagaaaaat cctagaaaaa ttcctagtat tacagccaca agaatggaac
     4321 ccagagctcg taatagggcg acatggaagg agttgccaaa ggcagaatag gtcgcaaaaa
     4381 gaacaatggg attgataaca ggtgctgtca caagaaaagg aacggccgtg taacttggaa
     4441 cctttttttc cagaaaacga ttgatgatgg ggacgattcc acattcacaa gaagggaaaa
     4501 gtataccgac aaaggtccca aaaaagattc tcccccaacg atttcgaggg agaaaatgat
     4561 aaaccttgtc aggtgtgata taaacttcaa tcagccctga gacaatgctt cctatcagaa
     4621 cgaagggaag ggcttcaatg ataatggaga gaaaaatggc tccagtttga agtacactag
     4681 atgggagttg ttgaaaagca gtcatctagt ttttcttttc tgctttgact tttttctctt
     4741 tgtcatcagg gaaagtaact tgtttcaaat cagggagttt agcaaactct tcaaacatct
     4801 tgtccaagtc gtctcgtttt gtaaatttga cagccatagg tgtacctcga ttctaaattc
     4861 tacctctatt atactattat tttgcggaaa agggaaaagt taaaatttca aattgagtag
     4921 ctaagagata atatagcttg at
//
LOCUS       DAVLUM010000098         4700 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLUM010000098 DAVLUM010000000
VERSION     DAVLUM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.098"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(471..1022)
                     /locus_tag="VYN42_001914"
     CDS             complement(471..1022)
                     /locus_tag="VYN42_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1462939.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1372..2196)
                     /gene="nadE"
                     /locus_tag="VYN42_001915"
     CDS             complement(1372..2196)
                     /gene="nadE"
                     /locus_tag="VYN42_001915"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1462940.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGCLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGFHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(2193..3653)
                     /locus_tag="VYN42_001916"
     CDS             complement(2193..3653)
                     /locus_tag="VYN42_001916"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1462941.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3769..4257)
                     /locus_tag="VYN42_001917"
     CDS             complement(3769..4257)
                     /locus_tag="VYN42_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462942.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4247..4456)
                     /locus_tag="VYN42_001918"
     CDS             complement(4247..4456)
                     /locus_tag="VYN42_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462943.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT         1356 a         1073 c          854 g         1417 t
ORIGIN      
        1 catcttatct aaatacatgc taatatattt agatacaaat attccaactt gataattttc
       61 actcatcttt catcattcct tatacaacta tgcagtataa atagaatagt tttctcatca
      121 gaatgagact attttaatat tagataattt gatagaaaaa cataaataaa attggttgaa
      181 tttaattccc taactcgata gaggattcta ttttaaattt aacaacagct aggattacac
      241 tataaaaagt acattaccac ctgttcggct ggagaatcta gtcgattagc tccctcttag
      301 ttacaagctt caagcgattt tttaactaat actaaaccag attaaagaag gaactagagc
      361 atctgtcttg tactaatcaa tatgctattt taaaattgca aataaacttg gaatgctaat
      421 tattatattt acaataaata gttgacttcg atagaaacag aaaatagaat tcaacattct
      481 tccctactta taccataata aataagatcc gcaagatagc cttttctctc tacaccatta
      541 acaatggttt gtagatagga cattccagcc ttttccatga cacggcctga agctgggttg
      601 agactggcat aacgtgctct gaccttttga aaacctgctt gagtaaaaca aaagtccaag
      661 acagctttca aggcctctgt catcatacca tgtccccagt aagccttgcc tagcacatag
      721 ccgatttcac agcttaaatc agcctcgtct atcttaacga tgctgatatc tcctatcact
      781 tgctctgggt tttcttttag acaaatggcc catttgtaat agttgagatt agtataggaa
      841 gcaacccaat tgcgaatcga gtttcgagtg atttcgacat caggatgggg atcccaggta
      901 acataggtca gattctcagc ggatgaagcc caattttgaa acatggcttc tgcatcactc
      961 tccacaaatc ttcttaaaat caaacgttct gtctgtaata tttgcgtacc aatagatttc
     1021 atgatgctac ctcacttcct tatttctatg ctcgtagtaa aaaggctcaa ctcagtaaca
     1081 gctagaaaac gagtttgtct tctaatttct tgacgcagtc gctgcctggt ttgaaatgcg
     1141 atctagcaag ctttttcaaa cctagtcatc gttgcagggg taagacgatg aaatcgaact
     1201 cttcgagtta ccgaatctgc ctcattttct tatttctaaa ctcggggttc aagatccccc
     1261 agaccttctc tcactttctt attttaagat gagaggctga aaacctccag tggaggtttt
     1321 tcttgctttt taatttcagg gcaagaagct aaaaaggtcc cccggacctt tttactccca
     1381 aaagtcatca aatacggtga tgggtaagtg gcgtttgtgt tggcctttgt gccaccagtt
     1441 ttcaatggtc gcttgagctt ctgggctgat tgttttgcct tctaggtagt cgtcaatctc
     1501 tgcgtaggtg actccaagtg cgacttcgtc agctaggcct ggtttatctt cttctagatc
     1561 tgccgttggg attttttcat aaagggctgg ctctgcgcca agtttctgca agagctgttt
     1621 tccttggcgt ttattgaggc ggtaaagagg gagaatatcc gcaccgccgt caccaaactt
     1681 ggtaaagaaa cctgtgatat tttccgcggc gtggtctgtt ccaatgaccg ctccgctatg
     1741 gaaaccagca agggcatact gagcaatcat acggcaacgt gccttgatat tccccttgtt
     1801 gaagtctgaa acaggactac ctgtcgcttc aactgcagct gtcatggcat cagctgattc
     1861 cttgatattc acaaccaagc tgacatctgg ctggatgaag gctagggctt tttgagcatc
     1921 tgcttcatca gcttgcactc cgtatggcag gcggacagcg ataaatttgt agctatcgtc
     1981 tcccgtttca gctcgcagtt cttccatagc taattgcgcc aaacatcctg ccaaggttga
     2041 gtcttgtccc ccagaaatcc ctagtacaaa ggtttttagg aagggatgtt ttttcagata
     2101 tctttttaag aaatcaatag aacgacggat ttcttcctgg gcatcaatca ctggtttgac
     2161 acccagctct tggataatcg tttcttgcaa actcattctt cttctccttc accaagggct
     2221 tccttgcgca tcttatcaat caagtccatc ttatcttgcc atacatcacg cgccaaatcc
     2281 actggatagt gctgcggatt gagcacacgc ttatactcat cccacaactt gtcaaattcc
     2341 ttacgggcat aatcctgaat gtcagtcaaa ctaggcaagt tgtaaactaa tattccttct
     2401 ttgaagatat ccaccaagag aggaacggca tcaaaattac gaaccgtctt cttgatgtat
     2461 gtataggtcg gatggaacat cttgatttct gtcatgtcgc taatatccac accatcataa
     2521 gtgatatagt cgccttctga cttgcctttt tcacgactgg taatgcgcca cacctgcttc
     2581 ttacctggcg tagaaacttt ttcagcatta ttagacagct taatcgtatt gcgcatctga
     2641 ccagtttcat cttcgattgc aacaatcttg taaactgcac caagagctgg ctggtcataa
     2701 gctgtaatca gcttggtacc cacgccccag acatcaatct tggccttttg catcttgagg
     2761 ttaaggatgg tattttcatc tagatcatta gaagcataaa tcttagcctc tgtaaatcca
     2821 gcctcatcca gttgctgacg gactttctta gaaatgtagg caatatcccc agagtcaatc
     2881 cgcacaccca taaagttaat ctgatcaccc agctcacgcg ccacctgaat ggcagctggt
     2941 acaccgatgc gaagggtgtc ataggtatcc acaagaaaga cacaattttt gtgggtcgca
     3001 gcgtaagcct tgaaagcttc atagtcattg ccataaacct gtaccaaggc atgggcatgg
     3061 gttcccaaaa caggaatgtc aaagagctta cccgcacgca cgttgctggt tccattggcc
     3121 ccaccaatca ccgctgcgcg tgttccccag atggccgcat ccatttcttg agcccgacgt
     3181 gtcccaaact ccatcaaggg ttcatcttcg ataaccgaac gaatacgagc tgccttcgtc
     3241 gccaccaagg tctggtagtt gacgatgttc aaaagagccg tttcgaccaa ctgacattgg
     3301 gctagaggtc cttccacctg cacaatcggt tcattagcaa aaaccaaatc cccttcttgg
     3361 gcagaacgaa cggtcaactc caacttgaaa ttgcgaaggt aatccaagaa cgccccatga
     3421 taaccaagcg actccaaata ggctatatca ctatctgaaa aacgcaagtc ttcaagatag
     3481 ttcacaattc tttccaaacc tgcaaaaacc gcatagccgt tcttaaaagg ctgttggcgg
     3541 aaatacacct caaagaccgc cttcttattg tgaatccctt ggtcaaagta aacctgcatc
     3601 atgttgatct ggtacaagtc cgtgtgcaat gtcaaactat catctggata catacttttc
     3661 ctacttcctt agctagaaac ccatgaaaat tttcaagaac tttcatgtat tccaataaat
     3721 tagtactatt atatcacatt ttagctggat tgagaaaaga gtaacaagct attctccact
     3781 ctccaattca tccatatctt gttcaaattt tttctgagcc cattcgccat agctcttaag
     3841 accaagattg ccaataaaga cccacggaag gtaaatgaca taagtaatga cccaagcaga
     3901 caggtattta aaattcaaag gattgtgctg ataaatttct atgttgaatt gataattctg
     3961 caacatcaaa agagccgtaa tagccaaggt taggaaaaaa caacccaaaa tcgtaaaatg
     4021 aaaacgacta tagtaggtca ctcccagata acgggcgcga ttgaaaaagt aaaatgtccc
     4081 tatgatgata acgattagca gcatattaga attaaaaagg cttggtgcta atactgaaat
     4141 gatataagat aggagcgaca aagcaatgca gatatagaaa ctttcagagc ccgctttatt
     4201 gaacagttgt tcttctcttt cgtctagtaa ttgataataa taaaatctat ttttcatctt
     4261 cttcctccca aaatagttgg tctagggttt tccctaaaca tctgcaaata gactggcaga
     4321 gcgagagact gggattgtat tttcccgcct ctatcaaacc aatagtctgg cgtgtcaccc
     4381 cgacagcctc tgccagttga ccttgtgtta aatcacgctc tacccgagct aattttaatt
     4441 ttaaattttt agccaccttc gtcctcctta tagttttaat actcatctac tcttaaaaaa
     4501 tccaaaacca acacaagcta tcagctattt attataaccc cattaatttg cactccagta
     4561 ttatcttcag ccgaaaatca gtattttagg ttgtttgaaa taaacttcct agtttactct
     4621 tttattttta tttagtatta gctttagtag gatcttttaa acgagttttt attgcttata
     4681 tttcttgttt agtttagttg
//
LOCUS       DAVLUM010000099         4582 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLUM010000099 DAVLUM010000000
VERSION     DAVLUM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.099"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..1257
                     /locus_tag="VYN42_001919"
     rRNA            <1..1257
                     /locus_tag="VYN42_001919"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1309..1381
                     /locus_tag="VYN42_001920"
     tRNA            1309..1381
                     /locus_tag="VYN42_001920"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1342..1344,aa:Ala,seq:tgc)
     gene            1506..4407
                     /locus_tag="VYN42_001921"
     rRNA            1506..4407
                     /locus_tag="VYN42_001921"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4484..>4582
                     /gene="rrf"
                     /locus_tag="VYN42_001922"
     rRNA            4484..>4582
                     /gene="rrf"
                     /locus_tag="VYN42_001922"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1274 a          942 c         1358 g         1008 t
ORIGIN      
        1 atagccgacc tgagagggtg atcggccaca ctgggactga gacacggccc agactcctac
       61 gggaggcagc agtagggaat cttcggcaat ggacggaagt ctgaccgagc aacgccgcgt
      121 gagtgaagaa ggttttcgga tcgtaaagct ctgttgtaag agaagaacga gtgtgagagt
      181 ggaaagttca cactgtgacg gtatcttacc agaaagggac ggctaactac gtgccagcag
      241 ccgcggtaat acgtaggtcc cgagcgttgt ccggatttat tgggcgtaaa gcgagcgcag
      301 gcggttagat aagtctgaag ttaaaggctg tggcttaacc atagtaggct ttggaaactg
      361 tttaacttga gtgcaagagg ggagagtgga attccatgtg tagcggtgaa atgcgtagat
      421 atatggagga acaccggtgg cgaaagcggc tctctggctt gtaactgacg ctgaggctcg
      481 aaagcgtggg gagcaaacag gattagatac cctggtagtc cacgctgtaa acgatgagtg
      541 ctaggtgtta gaccctttcc ggggtttagt gccgtagcta acgcattaag cactccgcct
      601 ggggagtacg accgcaaggt tgaaactcaa aggaattgac gggggcccgc acaagcggtg
      661 gagcatgtgg tttaattcga agcaacgcga agaaccttac caggtcttga catccctctg
      721 accgctctag agatagagtt ttccttcggg acagaggtga caggtggtgc atggttgtcg
      781 tcagctcgtg tcgtgagatg ttgggttaag tcccgcaacg agcgcaaccc ctattgttag
      841 ttgccatcat ttagttgggc actctagcga gactgccggt aataaaccgg aggaaggtgg
      901 ggatgacgtc aaatcatcat gccccttatg acctgggcta cacacgtgct acaatggctg
      961 gtacaacgag tcgcaagccg gtgacggcaa gctaatctct taaagccagt ctcagttcgg
     1021 attgtaggct gcaactcgcc tacatgaagt cggaatcgct agtaatcgcg gatcagcacg
     1081 ccgcggtgaa tacgttcccg ggccttgtac acaccgcccg tcacaccacg agagtttgta
     1141 acacccgaag tcggtgaggt aaccgtaagg agccagccgc ctaaggtggg atagatgatt
     1201 ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac ctcctttcta
     1261 aggataagga actgcgcatt ggtcttgttt agtcttgaga ggtcttgtgg ggccttagct
     1321 cagctgggag agcgcctgct ttgcacgcag gaggtcagcg gttcgatccc gctaggctcc
     1381 attggtgaga gatcaccaag taatgcacat tgaaaattga atatctatat caaatagtaa
     1441 caagaaaata aaccgaaaac gctgtagtat taataagagt ttatgactga aaggtcagaa
     1501 aataaggtta agttaataag ggcgcacggt ggatgccttg gcactaggag ccgacgaagg
     1561 acgtgacaaa cgacgatatg ccttgggtag ctgtaagtaa gcgatgatcc agggatttcc
     1621 gaatggggga acccaacagg taatacctgt tacccacatc tgttaaggat gtgaggagga
     1681 agacgcagtg aactgaaaca tctaagtagc tgcaggaaga gaaagcaaaa gcgattgcct
     1741 tagtagcggc gagcgaaacg gcagaagggc aaaccgaaga gtttactctt cggggttgta
     1801 ggactgcaat gtggactcaa agattataga agaatgattt gggaagatca gccaaagaga
     1861 gtaatagcct cgtatttaaa atagtctttg tacttagcag tatcctgagt acggcgggac
     1921 acgtgaaatc ccgtcggaat ctgggaggac catctcccaa ccctaaatac tccctagtga
     1981 ccgatagtga accagtaccg tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat
     2041 agaacctgaa accgtgtgcc tacaacaagt tcgagcccgt taatgggtga gagcgtgcct
     2101 tttgtagaat gaaccggcga gttacgttat gatgcgaggt taagttgaag agacggagcc
     2161 gtagggaaac cgagtctgaa tagggcgcct tagtatcatg acgtagaccc gaaaccatgt
     2221 gacctaccca tgagcaggtt gaaggtgcgg taagacgcac tggaggaccg aaccagggca
     2281 cgttgaaaag tgcttggatg acttgtgggt agcggagaaa ttccaaacga acttggagat
     2341 agctggttct ctccgaaata gctttagggc tagcgtcgac attagagatt cttggaggta
     2401 gagcactgtt tgggtgaggg gtccatcccg gattaccaat ctcagataaa ctccgaatgc
     2461 caatgaatta tggtcggcag tcagactgcg agtgctaaga tccgtagtcg aaagggaaac
     2521 agcccagacc accagctaag gtcccaaaat aattgttaag tggaaaagga tgtggggttg
     2581 cacagacaac taggatgtta gcttagaagc agctattcat tcaaagagtg cgtaatagct
     2641 cactagtcga gtgaccctgc gccgaaaatg taccggggct aaaacaattt accgaagctg
     2701 tggatacctt tataggtatg gtaggagagc gttctatgtg tgatgaaggt ataccgtgag
     2761 gagtgctgga acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat
     2821 cctgtccacc gtaagactaa ggtttccagg ggaaggctcg tccgccctgg gttagtcggg
     2881 acctaaggag agaccgaaag gtgtatccga tggacaacag gttgatattc ctgtactaga
     2941 gtatgtagtg atggagggac gcagtaggct aactaaagca gacgattgga agagtctgtc
     3001 taagcagtga ggtgtgaatt gagtcaaatg cttaattcta taacattgag ctgtgatggg
     3061 gagcgaagtt tagtagcgaa gttagtgacg tcacactgcc aagaaaagct tctagcgttt
     3121 aaacatactc tacccgtacc gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg
     3181 agcgagagaa ctctcgttaa ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg
     3241 tgctgactta aagtcagccg cagtgaatag gcccaagcaa ctgtttatca aaaacacagc
     3301 tctctgctaa atcgtaagat gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta
     3361 agaggagtgc ttagcgtaag cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa
     3421 ctataacggt cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg
     3481 cgtaatgatt tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga
     3541 tgcaggttac ccgcgacagg acggaaagac cccatggagc tttactgcag tttgatattg
     3601 agtgtctgta ccacatgtac aggataggta ggagtctaag agatcgggac gccagtttcg
     3661 aaggagacgc tgttgggata ctacccttgt gttatggcca ctctaaccca gataggtgat
     3721 ccctatcgga gacagtgtct gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta
     3781 acggaggcgc ccaaaggttc cctcagaatg gttggaaatc attcgcagag tgtaaaggta
     3841 taagggagct tgactgcgag agctacaact cgagcaggga cgaaagtcgg gcttagtgat
     3901 ccggtggttc cgtatggaag ggccatcgct caacggataa aagctaccct ggggataaca
     3961 ggcttatctc ccccaagagt tcacatcgac ggggaggttt ggcacctcga tgtcggctcg
     4021 tcgcatcctg gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac
     4081 gcgagctggg ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa
     4141 atttgagagg atctgctcct agtacgagag gaccagagtg gacttaccgc tggtgtacca
     4201 gttgtcttgc caaaggcatc gctgggtagc tatgtaggga agggataaac gctgaaagca
     4261 tctaagtgtg aaacccacct caagatgaga tttcccatga ttatatatca gtaagagccc
     4321 tgagagatga tcaggtagat aggttagaag tggaagtgtg gcgacacatg tagcggacta
     4381 atactaatag ctcgaggact tatccaaagt aactgagaat atgaaagcga acggttttct
     4441 tgaattgaat agatattcaa ttttgagtag gtattactca gagttaagtg acgatagcct
     4501 aggagataca cctgtaccca tgccgaacac agaagttaag ccctagaacg ccggaagtag
     4561 ttgggggttg ccccctgtga ga
//
LOCUS       DAVLUM010000100         4302 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLUM010000100 DAVLUM010000000
VERSION     DAVLUM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4302
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.100"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            720..1712
                     /locus_tag="VYN42_001923"
     CDS             720..1712
                     /locus_tag="VYN42_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1462944.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VYN42_001924"
     CDS             1714..2532
                     /locus_tag="VYN42_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1462945.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VYN42_001925"
     CDS             2534..3319
                     /locus_tag="VYN42_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1462946.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLILISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VYN42_001926"
     CDS             3417..3635
                     /locus_tag="VYN42_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1462947.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3766
                     /locus_tag="VYN42_001927"
     CDS             3620..3766
                     /locus_tag="VYN42_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1462948.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFP"
     gene            complement(4205..4302)
                     /locus_tag="VYN42_001928"
                     /pseudo
     CDS             complement(4205..4302)
                     /locus_tag="VYN42_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         1191 a          745 c          920 g         1446 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gtttataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccagact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgacg gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtcattt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggggagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccga aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatatt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgct gagattttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca aacctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaagcttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagc ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt ccttaactat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctatttttta
     3841 ttctcagagt gctatactgt aagtgtaatc gccgatttag ctcagttggt agagcaaggc
     3901 actcgtaaag cctaggttat aggtagataa acgactgagg agttgaaaaa atagataggt
     3961 agaagataac cgttaagcct tactcttagc ggttatttat attgtttaat agcgctaata
     4021 tttcatcaat tatgcctgtt ttcgtgtttc tggtagttgt tcaagtttat tgctactatt
     4081 tttgatggta tgaatgtgct tataatgtat cccggttaac gaaagttttg gacttatact
     4141 cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc gtgcgtatgg ttactgacta
     4201 cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag
     4261 tttgctcttt gattttcatt gagtactaat cttatttttt aa
//
LOCUS       DAVLUM010000101         4295 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLUM010000101 DAVLUM010000000
VERSION     DAVLUM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.101"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            112..1137
                     /locus_tag="VYN42_001929"
     CDS             112..1137
                     /locus_tag="VYN42_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1462949.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNILG
                     NACKNAK"
     gene            1127..2134
                     /locus_tag="VYN42_001930"
     CDS             1127..2134
                     /locus_tag="VYN42_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1462950.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2134..3141
                     /locus_tag="VYN42_001931"
     CDS             2134..3141
                     /locus_tag="VYN42_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1462951.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3141..3935
                     /locus_tag="VYN42_001932"
     CDS             3141..3935
                     /locus_tag="VYN42_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1462952.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
     gene            4226..>4295
                     /locus_tag="VYN42_001933"
     CDS             4226..>4295
                     /locus_tag="VYN42_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV1462953.1"
                     /translation="MRKYNQLVKTIKEEIKTLKGWIG"
BASE COUNT         1563 a          615 c          726 g         1391 t
ORIGIN      
        1 aaaactagat ccttttttga aaaaattata ttattaaatt tgtaactgca tctattgaca
       61 atgataatta ttatcgatac aatagacttg aaatatgttt aaggagtttt tatgaaaaac
      121 aaattttttc taatagctat tttagctatg tgtatagttt ttagcgcttg ttcttctaat
      181 tctgttaaaa atgaagaaaa tacttctaaa gagcatgcgc ctgataaaat agttttagat
      241 catgctttcg gtcaaactat attagataaa aaacctgaaa gagttgcaac tattgcttgg
      301 ggaaatcatg atgtagcatt agctttagga atagttcctg ttggattttc aaaagcaaat
      361 tacggtgtaa gtgctgataa aggagtttta ccatggacag aagaaaaaat caaagaacta
      421 aatggtaaag ctaacctatt tgacgatttg gatggactta actttgaagc aatatcaaat
      481 tctaaaccag atgttatctt agcaggttat tctggtataa ctaaagaaga ttatgacact
      541 ctatcaaaaa ttgctcctgt agcagcatac aaatctaaac cttggcaaac tttatggaga
      601 gatatgatta aaattgattc aaaagcctta ggtatggaaa aagaaggtga tgagttaatc
      661 aaaaatactg aagctcgtat atccaaagaa ttagaaaaac atccagaaat caaaggaaaa
      721 atcaaaggaa aaaaagtatt atttactatg attaatgctg cagatacatc aaaattctgg
      781 atttatacta gcaaagatcc aagagcaaat tatttaacag atttaggtct agttttccct
      841 gaatcattaa aagaatttga gagtgaagat agttttgcaa aggaaatttc tgcagaagaa
      901 gcaaataaga taaatgatgc tgatgtaatc ataacttatg gtgatgataa aactcttgaa
      961 gctttacaaa aagatcctct tttaggtaaa ataaatgcaa ttaaaaatgg tgccgttgct
     1021 gtaattccag ataatacacc gttagcagcc tcatgcactc caacaccact ttcaataaac
     1081 tatactattg aagaatacct aaatatttta ggaaatgcat gcaaaaatgc gaaataaaaa
     1141 acaaataaac ctaggcataa tttttgtaat ctgcctaggt cttcttatta caatattttt
     1201 gtcattaaag cttggaacaa aagaaattaa tatcagagat tttttagcag cttttggaat
     1261 gggcaataca aatgatgatt ttattaaatc aattatatat aaaagaatac ctagaactat
     1321 ttttgcaatt ttagcaggtt ctagtcttgc cataagcggt gtattgatgc aatcagttac
     1381 tagaaaccca atagctgatc caggtatact cggtataaac acaggagcaa gtcttagtgt
     1441 agtaattggt ctttcttttt taggaatttc atcaagcata agccatataa gttttgcaat
     1501 cattggtggc ttagtaagtg caatttttgt atacgcgatt gctgtaagcg gaaaagcagg
     1561 ccttacccct ataaaacttg ccttatcagg aacttgtgtt agtatggctt taagcagttt
     1621 tgtaagtttt ttaattttac cgaataataa cgtcttagac aaatttagat tttggcaaat
     1681 aggtagcctt ggagcagcta cattatcttc tatatctaca ctactacctt ttataatttt
     1741 aggtcacttg atagctatat ttatttcatc agatttaaac gctttagcta tgggtgatga
     1801 aatggctgtt ggtcttggag ttaatgttaa taggataaga tcacttgcaa taattgcaag
     1861 tgtgctttta tgttcaagta ttactgcaat tggtggacct attggcttcg taggtcttat
     1921 agttcctcac ttttgtggct tatttataag caaagatata cgcacaatga ccatttcttc
     1981 atcttttata ggtgcagagc tcttgcttat atgtgatata atcggccgta tgttaggtaa
     2041 accaggtgaa attgaagtag ggataattac tgcaataatc gggggtccag tacttattta
     2101 tgtaactatg aaaaatagag gggttaataa ctaatgcaaa atttaattat aggtattcaa
     2161 aaaagaaaaa atagaataac actattttcc tcactatttt tattaataat aatcagtcta
     2221 tcatttttca ttttacttat cggagatgaa agttattctt tttcaacttt gattaaagtc
     2281 ttaaatagtg aaactgttcc tggagctagt ttttcgatta tggaaattag attaccaaaa
     2341 ttattagcag gaattatagc tggctggtct tttggattgg caggatttat ctttcaaact
     2401 atgttaagaa atcctcttgc aagtcctgat ataatcggtg tcacaagttc ttcatctatt
     2461 gcagcggtct tttgcatatt ggtattaaaa acaaatagtt taactactgg aattatttca
     2521 ataacttgtg gactaacatc atctttaata ttatttttac tagctaaaaa agatggtttt
     2581 tcagcagcaa gactgataat attaggtatt ggttttcaag ctgtcacaag agcaggcacc
     2641 tcatttttat tgttgaaagt agcaagatat gaattacaag aagttatgag atggctcagt
     2701 ggctctttat cttttacaaa gttagatgac atacctcttg ttctaatagt aagtattatt
     2761 gctactatat tagttttatt ttttaataaa agactagaaa ttattgaact tggtgaagaa
     2821 atagcaatcg gacttggagc aaatcccgag ctttcaaggc ttgttttaat tttttgcgct
     2881 gtatctttaa ctgctttttc tacttcaatt acaggaccaa tagcttgtat atctttttta
     2941 gctggtccca tagccttaaa tattggcaag aaaagaagcc caatattagc tggattggtt
     3001 ggaattttac tagttttgtt atcagacata ttctctcaaa atattttacc agctagatat
     3061 ccagtaggtg ttgtaactgg cttgttaggt tcaccatact taatatactt actaataaaa
     3121 atgaacagga ggaatatata atgaaaggtc tgtggtcaaa taatcttacc tgcggttatg
     3181 atgaaaaaat aatcttggaa aatataaata taaaaatacc tgaagaaaaa atatcagtta
     3241 ttattgggtc aaatggttgt gggaaatcaa cactcattaa aaccttgtct cgacttataa
     3301 agccattaga gggagaagta ttgcttgata ataaatcaat taattcttat aaagaaaaag
     3361 atttagcaaa acacatagct atattacctc aatctccaat aatccctgaa tcaataacag
     3421 tagctgatct tgtaagccgt ggtcgtttcc cctacagaaa gccttttaag agtcttggaa
     3481 aagatgacct tgaaataata aacagatcaa tggttaaggc caatgttgaa gatctagcaa
     3541 ataacctagt tgaagaactt tctgggggtc aaaggcaaag agtatggata gctctagccc
     3601 tagcccaaga tacaagtatc ctacttttag atgagccaac tacttacttg gatatctcat
     3661 atcaaataga actattagac ctcttgactg atctaaacca aaaatataag acaaccattt
     3721 gcatgatttt gcacgatata aatctaacag caagatacgc tgattaccta tttgcaatta
     3781 aagaaggtaa acttgttgca gagggaaagc ctgaagatat actaaatgat aaactagtta
     3841 aagatatctt taatcttgaa gcaaaaatta tacgtgaccc tatttccaat tcgcctctaa
     3901 tgattcctat tggcaagcac catattaact cttaataatt gaatattgga attcatttaa
     3961 aagtcgcaaa ttttgaactg accctcaaaa gttaggccaa aaaactaact aaaggaggtc
     4021 agttttttaa tggcaaatac agcacagaat ttaagataaa attagtaaaa gaatatcatg
     4081 aatgaaaaat aggatataga gaataacagc aatattaaaa agatcaggac tgataataaa
     4141 caaaaagaaa gtacaacgac tagttcaaaa gctaaaactt caagtaaaaa gttattcaag
     4201 aaaataggga aactataata gagaaataag aaaatataat caacttgtaa aaacaataaa
     4261 agaagagata aaaacattaa agggttggat aggaa
//
LOCUS       DAVLUM010000102         4280 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLUM010000102 DAVLUM010000000
VERSION     DAVLUM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.102"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            1..185
                     /locus_tag="VYN42_001934"
                     /pseudo
     CDS             1..185
                     /locus_tag="VYN42_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            352..552
                     /locus_tag="VYN42_001935"
     CDS             352..552
                     /locus_tag="VYN42_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462954.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            594..998
                     /locus_tag="VYN42_001936"
     CDS             594..998
                     /locus_tag="VYN42_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462955.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1229..1936
                     /gene="ccdA2"
                     /locus_tag="VYN42_001937"
     CDS             1229..1936
                     /gene="ccdA2"
                     /locus_tag="VYN42_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1462956.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1947..2504
                     /gene="sdbB"
                     /locus_tag="VYN42_001938"
     CDS             1947..2504
                     /gene="sdbB"
                     /locus_tag="VYN42_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1462957.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2878..4269
                     /locus_tag="VYN42_001939"
     CDS             2878..4269
                     /locus_tag="VYN42_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1462958.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYRIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
BASE COUNT         1249 a          774 c          909 g         1348 t
ORIGIN      
        1 gtcagttaat aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag
       61 gtctaacaaa tggtgaatta atcgctccaa tgacttacga agagatgatg acgagcgact
      121 tttttgaagt atggtttcag aagtttttct taccaacatt aaccacacca tcggttatta
      181 tagtaaaatg aaataagaat aggacaaatc gatcaggaca gtaaaatcga attctaacaa
      241 tgttttagaa gtccatatgt actattctag tttcaatata ccataactgt tcctagtcaa
      301 cctgcaagcc ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca
      361 agcgcttcgg ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt
      421 cgtgccttga gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatccg
      481 aaaatcgatg caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc
      541 ttgacagagt aaggtctgca tactgcagta gagtctgtga aggctgggct gccttggact
      601 ctctcaaaga tgtgaaagca aatgctagcg acagcaagcc tgcacaggac aagaaggatg
      661 caaaacaagg aacggaagat agtaaggatt cagataagat gactgaaaca aactcagttc
      721 cggcaggagt gattgtggtc agtctacttg ccctcctagg cgtgattgcc ttctggctga
      781 ttcgccgtaa gaaagagtca gaaatccagc aattaagcac ggaattgatc aaggttctag
      841 gacagctaga tgcagaaaaa gcggataaaa aagtccttgc caaagcccaa aaccttctcc
      901 aagaaaccct tgatttcgtg aaagaagaaa atggctcagc agagacagaa actaaactag
      961 tagaggagct taaagcaatc cttgacaaac tcaagtaaaa catgatttat gaaatgtcag
     1021 acctaaaaga cattttcgtt cacaaaagca gcgatgagta atccttgtcg ttgctttttg
     1081 gctattttgg gggataagat ccgccttgac tagcaaaaga aaagattggt ccaatagtgc
     1141 ccgatacgat tttgcgtagc agaaagctta caaataaaat tgaatatagt aaaataggat
     1201 tagaattatt aagaaagttg gttctttatt ggaaacgata gtatttttaa tctctgtttt
     1261 tctagcaggt gttttatcct ttttttctcc ttgtattttt cctcttctgc cagtctatgc
     1321 tgggatttta ttggatgatc aagaaagtgc aaaaagcttt tctttgtttg ggagaaaggt
     1381 tctctggtca ggcttgattc gaacactttg ctttatcgct ggtatctctc tcattttctt
     1441 tattctaggc tttggtgctg gttactttgg tcatattctc tatgcaaatt ggtttcgata
     1501 tgtcatggga gctattatta tcattttggg tcttcaccag atggaaattt ttcatttgaa
     1561 gaaattagaa gttcaaaaaa gttttacctt taaaaaatca gattctaatc gttattggtc
     1621 agctttttta cttggtatta cctttagctt tggttggaca ccttgtattg gtccagtttt
     1681 aagttctgtt ttagcacttg cggcttctgg aggcaatggt gcttggcaag gagcgattta
     1741 tactctcatt tacactctgg gcatggccct tcctttcttg gtcttggcac tagcttcagg
     1801 tctagtcatg ccatatttta gtaaaatcaa gcgtcatatg atgctactaa agaaaattgg
     1861 tggtttcctc attgttttaa tgggaatttt gttactatta ggacaagtaa atgttctagc
     1921 tggaattttt gaataaagga ggacaaatga aaaaagtaat gtttgctggc ttaagtctct
     1981 tgtcattagt tgtattgatg gcctgtggtg aggaagaaac taaaaagact caagcagcac
     2041 aacagccaaa acaacaaacg actgtacaac aaatttctgt tggaaaagat gctccagact
     2101 ttacattgca atccatggat ggcaaagaag ttaagttatc tgattttaag ggtaaaaagg
     2161 tttacttgaa gttttgggct tcatggtgtg gtccatgcaa gaaaagtatg ccagagttga
     2221 tggaactagc ggcgaaacca gatcgtgatt tcgaaattct tactgtcatt gcaccaggaa
     2281 ttcaaggtga aaaaactgtt gagcaattcc cacaatggtt ccaggaacaa ggatataagg
     2341 atatcccagt tctttatgat accaaagcaa ccaccttcca agcttatcaa attcgaagca
     2401 ttcctacaga atatttaatt gatagccaag gaaagattgg aaagattcaa tttggtgcta
     2461 tcagtaatgc ggatgcagaa gcagcattta aagaaatgaa ctagaatcga taaaatctga
     2521 ttacaagatg tagtcagatt ttggtaactt ctaaaactaa cttccagttt cccacaacct
     2581 agcttttagt atgagaaaaa cgcgtgacat cagtggaaat ccgtcttaga ctaacttcca
     2641 ctggttttct ttttcttgat atataagggt tcaaaagcga aaagactcag aaaaagtgca
     2701 cgacaaatag ccctaaaaca gagtcgtctt agagtaactt ccagttttgg gagagagatg
     2761 gaagttactt tgagaagtta cggtagtcag atttttttag aaaaacattt tataaatatt
     2821 cacatatctc ctatatttat ggtaaaatag aattatcagt ttattttgga gtcaaagatg
     2881 aatatattta gaacaaagaa tgttagttta gataaaacag agatgcatag gcatttgaag
     2941 ttatgggatt tgattttgct gggtatcgga gccatggtag ggacaggcgt ctttacaatc
     3001 acaggtactg cagctgcaac acttgctggc ccagccctag tgatttcaat cgttatttct
     3061 gccttgtgtg tgggattatc agccctcttt tttgcagaat ttgcctcgcg agtacccgct
     3121 acaggaggtg cctatagtta cctctatgct atcttaggag aattccctgc ctggttggct
     3181 ggttggttaa ccatgatgga gttcatgaca gccatatcag gcgtagcttc gggttgggca
     3241 gcttatttta aaggcttgct ctctcaatac aggatagcct ttcctcaggc tttaaatggt
     3301 acctttaatc ctcaagcagg gacatttgtt gatttattgc ctattcttgt cttggtcttg
     3361 gtgacttcgc ttgttttact aaatgccaag gcagccttac gctttaattc gattctagtt
     3421 attttgaaat tttccgcttt agctctcttt gttttagtag gaatttggaa tattaagttt
     3481 gataattgga gcaattttgc tccttacggt tttggacaaa tctatggagc tagcactggt
     3541 attatggctg gtgcgtcctt gatgttcttc ggttttttgg gatttgaatc catctctatg
     3601 gctgtagatg aagtcaagac tcctcaaaaa aatattccta gagggattgt cttatcgctt
     3661 tctatcgtaa ccattctcta tgccttggtg acccttgttt tgactggtgt ggttcactat
     3721 agtcatttaa atgtcgatga tgccgttgcc tttgcccttc gtagtgttgg gattagttgg
     3781 gcagccaact atgtgtcatt agtggctatc ttgaccttga ttacagtttg tatttcgatg
     3841 acctatgccc tatcgcgtat gatttacagt ttagcacgtg acggcttagt gcctgctgcc
     3901 tttaaggaac tgacgaagac tagcaagata ccaaagaatg ctactatctt gacaggtcta
     3961 gcttcagcag tagcagcagg aatgttccca ctagccagta ttgcagcctt tttaaatatt
     4021 tgtaccttag cctacttgat catgttggct tatggtctga ttcgcttacg gaaagaaaaa
     4081 ggaatgccca aagctgggga atttaaaaca ccattggtac ctctgttacc aattttatcg
     4141 atcatcattt gtttatcctt catgttacag tataatatga atacctggat tgctttccta
     4201 gttgcgttgt tagtaggaag tattatttac ttcacttatg gctataagca ttctaccata
     4261 gaagaataaa gtgaaagtct
//
LOCUS       DAVLUM010000103         4252 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLUM010000103 DAVLUM010000000
VERSION     DAVLUM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.103"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..336)
                     /locus_tag="VYN42_001940"
     CDS             complement(<1..336)
                     /locus_tag="VYN42_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462959.1"
                     /translation="MKKCWLTTNFEDYLKALSTNELTLLVKNLEIDLSEISIFYDVKF
                     EFYKKDRLSITDKGKTVDSESIIIYIGSNTKCQKIVELYASNRKYNFISYKSINNFLD
                     TEFEQKYAYV"
     gene            complement(359..1141)
                     /locus_tag="VYN42_001941"
     CDS             complement(359..1141)
                     /locus_tag="VYN42_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEV1462960.1"
                     /translation="MKQIILSTGSTSSLGLDNLATFEKFTKNKVYDYEIFFQSRLELT
                     ASEIKKVKEYCSQKGVSVNSIHPFMEGYEVPNLFSINIKKYAEAKDIFYRFLEICVLL
                     NSKYLIMHGPLQNCDWDNSIDRIKFFISEAKKYNVDIAIENKDYTLFYCPKRIILLKE
                     QLESDNWGFVLDFKSAWKANISLIDMVEAMGDRLLFSHVSFRDLENHKYGIPFQKFDK
                     SVYEIFSYMKEKYKTPRYVIEVDLVESEIDIIRTISHVEELL"
     gene            complement(1151..1777)
                     /locus_tag="VYN42_001942"
     CDS             complement(1151..1777)
                     /locus_tag="VYN42_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1462961.1"
                     /translation="MKVGDKVKKALIITAHPDDAEISMGGHIINMVNNGYYVKLLVLS
                     VPEDKTRILEAGKSAEFLGIELKIVGDKSQVSQFSSSELVSIIDNEIEEFDPSYVFTH
                     WENDAHKDHRIIFKAVQSSSRCHSFTFLSFSPPNIYVSNALQFVPNIFVEINIEKKLR
                     AIEFHRSQVNQKSYPIDGPKVQSVLFGKHIGVDYAEGFILIRHIDRKC"
     gene            complement(1761..3056)
                     /locus_tag="VYN42_001943"
     CDS             complement(1761..3056)
                     /locus_tag="VYN42_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1462962.1"
                     /translation="MKNNFLSRIQNKKANITIWGAGYIGLSTAYHFALVGFRVKIFDT
                     NHRLIQNLLEGNLPFKIDLDEEIFSKLIFNKSILPEVVEHADTYSDEIQIICINTERN
                     GVPISRPLTTVLDNITTVSEQLVIVESTISPNWIDTIIRPKLNDLQYLTVAPRRDWFL
                     ETGLNLKTLPRVIGTLGSNYRMEVLKLYEMLSYVVIEVTDAYHACLVKAVENSIRYIN
                     VVFANEMMRAFPRYNMAEIFDAASTKWNIPYYHPSIGIGGYCLPLAPKYILDAVNDSE
                     ELPMLRESVKSDLKQSDFITDLIKSYNCQKVVVLGLSYAPETKIWKNSPAVSLIYSLL
                     RNGIEVKINDPYFSSEEIQEITTVQSFSLNSESLQEFDILVIATSHKSYDGELERILF
                     DLNKEMIIFDNFGVNKNLSKLPNIHYFEIGNFQYNESRR"
     gene            complement(3157..3228)
                     /gene="shp3"
                     /locus_tag="VYN42_001944"
     CDS             complement(3157..3228)
                     /gene="shp3"
                     /locus_tag="VYN42_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEV1462963.1"
                     /translation="MKKISKFLPILFLVMDIIIIVGG"
     gene            3309..4160
                     /locus_tag="VYN42_001945"
     CDS             3309..4160
                     /locus_tag="VYN42_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV1462964.1"
                     /translation="MKSKLGVTLRKIRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTKTESFANLVQYIRKQYSSQNINNIQSLLSDS
                     SNYTLNSLEKTMVKSILHTMDSNVIPSDEELLQLTDYFFKVEKWGYYEIILLVNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKRIVTQLAINCLILSIDKKKFSNCSYLIDEIK
                     ELLDNELNFYEQTVFLYATGYFEFKRQLSSGIETMKQVIQVLDILGEDKLKLHYTSHF
                     DKLVNNK"
BASE COUNT         1484 a          747 c          507 g         1514 t
ORIGIN      
        1 cacataagca tatttctgtt caaactcagt atccaaaaaa ttatttatac ttttatatga
       61 aataaaatta tactttctat tgcttgcata taactctaca atcttctgac acttggtgtt
      121 acttccaata taaataatga ttgactcgct atctacagtc tttcctttgt ctgttattga
      181 taatctgtcc tttttataaa attcaaactt cacatcgtaa aaaattgaaa tttctgacaa
      241 atcaatttct aaatttttca caagtaatgt caattcgttt gtacttaatg cttttagata
      301 gtcttcaaag tttgttgtaa gccaacattt tttcatatct taactctctt ccttaaattc
      361 ataacagctc ctctacatga gaaattgtcc gaataatatc aatttcactc tctactaaat
      421 caacttcaat aacatatcta ggagtcttgt atttttcctt catgtatgaa aaaatttcat
      481 atacactttt atcaaatttc tgaaatggaa ttccatattt atgattttct aaatccctaa
      541 acgaaacatg agaaaataat aacctatcac ccatggcctc taccatatct attaaagata
      601 tattcgcttt ccaagctgac ttaaaatcta gaacaaaacc ccaattatca ctttctagct
      661 gttctttcaa gagaataatt cgcttaggac aatagaaaag tgtatagtct ttattttcaa
      721 tagctatatc aacattatac tttttagcct cagaaataaa aaactttatt ctatcaatac
      781 tattatccca gtcacaattt tgtaaagggc cgtgcataat taaatatttt gaatttaata
      841 atacgcatat ctctaaaaaa cggtagaata tatctttggc ttctgcatac ttttttatat
      901 ttatagagaa tagatttgga acctcatatc cctccataaa aggatgtata gaattaacac
      961 ttactccctt ttggctacaa tattctttta ctttttttat ttcagaagca gtcaattcca
     1021 atctagattg gaaaaaaatt tcataatcat atactttatt tttagtaaat ttttcaaaag
     1081 ttgctaaatt atctaaccct agagaactag tgcttccagt ggataatatt atttgtttca
     1141 tacttcctca ttaacacttt ctatctatgt gtctaatcag tataaatccc tctgcataat
     1201 ctactcctat atgtttacca aataagacag attgaacttt aggtccatct attggatatg
     1261 acttttgatt cacttgactt ctatggaatt caatagccct caactttttc tcaatattga
     1321 tttctacaaa aatatttgga acaaactgca aagcattgct aacatatata ttaggaggag
     1381 aaaacgatag aaaagtaaac gaatgacacc tactagagga ctgcacagct ttaaatatta
     1441 ttcgatgatc tttatgggca tcattttccc aatgtgtaaa aacataagat ggatcaaatt
     1501 cctcaatttc gttatcaata attgaaacta attcacttga actaaactga gaaacttgag
     1561 atttgtcacc aactattttt aattctatcc ctagaaattc tgcagacttt cctgcttcta
     1621 aaatcctcgt tttatcttct ggaactgata aaaccagtag tttgacataa taaccattat
     1681 taaccatatt aattatatgt ccacccatag aaatttcagc atcatctgga tgggcagtaa
     1741 ttattaatgc ttttttcact ttatctccta ctttcattat attggaagtt cccaatttca
     1801 aaataatgaa tatttggtaa tttagataga ttcttattca ctccaaaatt atcaaaaata
     1861 atcatttctt tatttaaatc aaaaagtatt ctctccaatt ctccatcata gcttttatgt
     1921 gaggtagcaa ttaccagtat atcaaattct tgtagtgact cactatttaa actgaaagat
     1981 tgaacagtcg ttatttcttg aatttcttca ctagagaaat atggatcatt tattttcact
     2041 tctattccat ttcttaacaa agaatagatt aaactaacag ctggggaatt cttccaaatt
     2101 ttagtctccg gagcataact tagacctaat actactactt tttgacagtt atagcttttg
     2161 attaagtcag taataaagtc agactgcttt aaatcagatt taactgactc cctcagcata
     2221 ggtaactcct cactatcatt gactgcatcc aaaatatatt taggagctaa cggaagacag
     2281 taccctccaa ttccaattga cggatgataa taaggaatat tccacttagt tgaagcagca
     2341 tcaaaaattt cagccatatt atatcttgga aatgctctca tcatttcatt agcaaataca
     2401 acattaatat agcgtataga attttcaacc gcctttacta aacaagcgtg atatgcatca
     2461 gttacctcaa tcacaacata agaaagcatt tcatataatt tcaaaacctc catacgataa
     2521 tttgatccca atgtaccaat aactcgagga agtgttttta aatttaatcc agtctctaaa
     2581 aaccagtctc tcctaggagc aactgttaga tattgcaaat cattcaactt tggtcttata
     2641 attgtatcaa tccaatttgg agaaattgta ctttcaacaa taactagttg ttcagatact
     2701 gttgttatat tatctaatac agtagttaat ggtctactaa taggtactcc atttctttca
     2761 gtattaatac agataatttg tatctcatca gaatatgtat cagcatgttc tacaacttct
     2821 ggtaaaatgg atttattaaa tattaactta ctaaatattt cttcatctaa atcaatttta
     2881 aatggcagat ttccttcaag taaattctgt atcaatctat gattagtatc aaaaattttg
     2941 acgcggaaac ctaccaatgc aaagtggtaa gctgtagata gacctatata tcctgcaccc
     3001 caaattgtaa tatttgcctt cttattttga attctactta ggaaattatt tttcatcgta
     3061 tgttaaactt tctacgttat tttattcata atttagtcat aatcaataga attagtcttt
     3121 agatactcta aagacttagg tgtacaccta agcattttat ccaccaacaa taatgataat
     3181 atccattacc aaaaacaaaa tcggtaaaaa ttttgaaatt ttcttcatac tctgacttcc
     3241 tttcattttt tatttattgt acaataaata agaaataagt taatttttgt taggaaaatg
     3301 ggaaaactat gaaatcaaaa cttggtgtca cacttagaaa aattcgtaag ggcaaacaaa
     3361 ttagtctatg ttctgtagct gatgagcatc tttcaaaatc gcaaatctct cgttttgaac
     3421 gtggggaatc agaaatatct tgtattcgac tgatcaatat tttagacaaa ttacacatta
     3481 cgttagatga gtttcttatt ttacacgatg aagactatac caaaactgag tcttttgcta
     3541 acttagtaca gtatatccgt aaacaatatt catcacaaaa catcaataat atacaatctc
     3601 tactttcgga ttcctcaaat tacaccttaa attctttgga gaaaacaatg gtaaaatcca
     3661 ttttacacac aatggattcg aacgtcattc catcagatga agagttactt caactaacag
     3721 actatttctt caaagttgaa aaatggggtt actatgaaat cattttatta gttaactgtg
     3781 tacgcacaat taactacaac tcctatttcc tattgacaaa ggagatgtta aataattaca
     3841 tctactcttc tctaaataaa accaataaac gaattgtcac tcaactcgca ataaattgtt
     3901 tgattcttag catcgataag aaaaaatttt ctaattgctc ctatttaatt gatgagataa
     3961 aggagttgtt agataacgaa ttaaatttct atgaacagac agtttttctc tatgccacgg
     4021 gttactttga atttaaacgt caattaagta gtggtattga aacaatgaaa caagttatac
     4081 aagttctcga tattttagga gaagacaagt taaaattaca ctatactagc cattttgata
     4141 aacttgtaaa caataaatga aatgattcct taccatctaa cgttttataa tcaagagtct
     4201 caataaaacc ttatcaactc cgatgaactt gtagttttaa ctatagacag at
//
LOCUS       DAVLUM010000104         4164 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLUM010000104 DAVLUM010000000
VERSION     DAVLUM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.104"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(280..1506)
                     /locus_tag="VYN42_001946"
     CDS             complement(280..1506)
                     /locus_tag="VYN42_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1462965.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1578..2243)
                     /locus_tag="VYN42_001947"
     CDS             complement(1578..2243)
                     /locus_tag="VYN42_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1462966.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2311..2508)
                     /locus_tag="VYN42_001948"
     CDS             complement(2311..2508)
                     /locus_tag="VYN42_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV1462967.1"
                     /translation="MLNLQFAETMELTEAELETVYGGELGYNAVIPGGSWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            complement(2794..3657)
                     /locus_tag="VYN42_001949"
     CDS             complement(2794..3657)
                     /locus_tag="VYN42_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1462968.1"
                     /translation="MIEKMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLANPQLIALFE
                     LRLQQYKKLID"
BASE COUNT         1446 a          785 c          747 g         1186 t
ORIGIN      
        1 gtgaagctga cgtggtttga agagagtttc gaagagtaca agtaggctga aaagaatcca
       61 gccacagcat ggactattat atagcagatt gaaataagat gagaacaaat cgattgggaa
      121 agtaaaatta atttctataa atgttttagc aattgtttcg tactatttta gattcagtct
      181 attataacac attcagaaaa gagaaaaaag tctgttgatt ttgaccatca taaaaagact
      241 ggcaatccag tctcaaacat atattataga aattctccac taaatacttt cacgaatatt
      301 cagaagcata acaaaggcaa ctagaagaaa tagcaataaa acaaagctaa ctgccagagt
      361 tccaaagcta gtagcaatgg ttaccaaagc tattgtaaat aagctaggta aaacaaccgt
      421 aatggcaccg atagaggatt gaactgctcc cattgactcc tcaggtattt gtttaaagac
      481 gagttcttgc aatctaggag agagaacacc tgcgaaaaag gcatccaagg tactaaagat
      541 gagaatccag tcaaaacgaa ctgtggcaaa tcctactaga agaagcaact ggatgacaag
      601 tgaggcatag agagctgttt ttatggaaat ggtatgttgc agatagccac ttacaaggct
      661 tccgacaatc agggctgaca gttcaaaagt ggatagcaag gcaagagatt gacctgtttg
      721 taaattcaaa aagggttgat tcctcaaaaa tagagtagag acaggaactg taacatttat
      781 cactgcttga ctagtagaga taataaacaa aaccaagagc accttattca tattccatat
      841 caatttcgat gattggagca aatgctggca aaaggatttt acagagagtc cttcttgata
      901 gttaatcgtt ttttctactt tcaagaggtc agtttttatg aagaggatac ctaaaaatgc
      961 gattaaaaag gtaagagcgt tcagcaagga aatgaactgg atggagagaa tccctagcaa
     1021 gactcctcct agaatattac tgattgtttt cactaaacta acagttgact gtttaaatcc
     1081 aatagcttct gccagatggt cttgcccaat aattctaatg aaaatcggag tgagcatggc
     1141 tcctgaaaag taactcaatg tgtcagacaa gaggttaagc agacaaataa atgctactag
     1201 caacaaggag aaagactgcc ctgaaagtga taaagaaacg atagagtaaa gcaaaaattt
     1261 tgcaaaacta atgactgtgt atttcaagac acgatgatgt tgaaaatctg ccaaaactcc
     1321 cagaaagatt tgtaaaattt ggggaagggt ttctgaaatc gtaatgagta aaatcgccaa
     1381 aggtgcaaaa gacgcatctg ccacataatt cagaaaggcc agataaaaaa tcgtatcccc
     1441 aagcgttgaa atccactggt tgatagttaa ttgcctaaaa tctctatttt gaagaaatac
     1501 tttcatcaca actccttctt aagttcaaat gggaatcttt ccccaaggat agaccgcgat
     1561 actactaaca accaaaatta cagtaacatc aaaagctgac caatgccatt gtagactata
     1621 tgcagtccaa taggccaata aattgacttt gtcattctaa ataagactgc aaatataaga
     1681 cctccaccca tatagaagac aaagtctgtc aagacccaac cgtgattact aatgtgcgag
     1741 accccaaata aaacagcgga accaagtaca tctagccccc atttctttcc tttttccaga
     1801 gcagtcatca ctaatccacg ataaatcatg tcttcaaaaa tgggacctgc aatcacagga
     1861 taaaaaaaat acatcaaaaa tgccgtagct cctgtaaaag taggagcagc atgttgataa
     1921 gaaatttcat ttcgagtagg tgggaaaaga aaaaaggtga caaaattcca agcaacaaaa
     1981 gcaagcagag ctaggaagga atagaaaaga taggatcctt taaactttct actattgatt
     2041 ttctgccatt tccccgacca aatcatagca ataagagcaa ataaaaccac aagaaaattc
     2101 aacatcatat ccgacagata ataggcaaag tcagatagcc cagcaacaag gtcgctgcgt
     2161 aaaactaaaa cactgaactt ctggtcagca ataactagta gaaaaactat aataaagtag
     2221 cggtgtgaga ttatcttttt cattctattt tctcctatac tatgaaataa agacagtccc
     2281 tacccaagaa aaaggcaagg actctgaata tcaataatgg cgacgattaa cagtggaaga
     2341 atcatggtta aaatatttct tccagaaatt agtgattgac caagacgttc ctaaacctcc
     2401 ccaactacca cctgggataa cggcattata cccaagttcc cctccataaa ctgtctccaa
     2461 ctcagcttct gtcaattcca ttgtttctgc aaattgtaaa tttaacatct tttacactcc
     2521 ttcaattatc ttcatttgta aaccacttct gcgacctagg atttgcttca agtgttttac
     2581 aagtacagta taacacgaaa attggcttat tttagaaaat cgcatatttg atattttttc
     2641 ttatagaaat ttcagatttg cgattttggt gaatttgatt acttctctgg tataataaag
     2701 ttactactaa tgaggagtgg agaaatacga agaaacaaat tttaacatta ttgaaaatcg
     2761 ttgctgagat tattattatt ttgccatttc taactaatcg ataagctttt tgtattgctg
     2821 caaacgcaat tcaaaaaggg ctattaattg tggatttgct aatacttgca gagattggat
     2881 aaagtgttca atctcttttt gattgcttcc cttagtttga aggaaaatgc tcatcttctt
     2941 taaaaactgc cacaataatt tctcaaaaac atcgtatgga cggagcatac tctccagctc
     3001 ggcttcaaag attgggatgt aggagaaaag ttttcgctcc atgagttctg ataagatatt
     3061 taagagtcct tgcttcatat acaatcgatt gtgtactaac tctttaaatt ctttggattt
     3121 ttcgagtaag gaggttgata aaaaaatcag atcttgattg ctcaagaagg gcatggtatt
     3181 gcaaaagaga tagagttcaa accaggtcca agactcgata gcatagagat aggtggtcaa
     3241 aaactcgcta tcctcctctg ctagtgggta gcttttattt agtgaatgga tggcatcttt
     3301 aatcacgatg gcattcaaac gacgataggt ctgcgccatc tgttcttgat cgacttcctc
     3361 caatagctgc tctaaagcag ctatatcctg atgggcaaag cgattcacaa cctttcgacc
     3421 gattcgcata tgtggagatt cttgatagtt gttgagcttg tgcccaaact catcaaaggt
     3481 cacatttata ccttggatag ctagaatcaa cttatccgca gacagcatag actgccctag
     3541 ttcaaacttg gacaactgag aagctgttag accctcacaa gccacatctg tctgcttaag
     3601 ctttctcgcc aaacgtaatt ccttgtaaaa ttcccccagt tccatttttt caatcatcct
     3661 accacctcct agcttttgca tattatatca ttatttgtgt tcatttgtca aaacattctg
     3721 acactttggt gattgaaaaa gccagcctta agctgactct aaaaggaccg agccttgtac
     3781 aatacagaac tcaatcctcg ttctaaatag aatgtctaac ttttttgggc agtacacgag
     3841 cttggggaac agccactgga acgatgaggg gtgagctcaa aatatcctcc agttatgttt
     3901 ttcctaatag tataccggaa gagtgaaagg attttataat ggagcggtta caaagaacct
     3961 actttctatt aaacagtata ctatgaaaat gtgaaaattt aacatttttt tgtacaaatt
     4021 ttataaatta ttgccttttt aatatcaata gttaatctct tatccagatc ccccttgtgt
     4081 aaactttatc tttataagct tcaaggcccc tatcccatct atttgcaaca attagatcac
     4141 tttgttttgt aaatagttca aaat
//
LOCUS       DAVLUM010000105         3961 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLUM010000105 DAVLUM010000000
VERSION     DAVLUM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.105"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            51..1262
                     /locus_tag="VYN42_001950"
     CDS             51..1262
                     /locus_tag="VYN42_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1462969.1"
                     /translation="MKIDKKNEAFLIVSRGISRIGDIMFDFANNTFLAGLNPTSLSLV
                     AVYQSLESVIGVLFNLFGGVIADSFKRKKIIIVANILCGIACIILSFISQEQWMVFAI
                     VITNIILAFMSAFSGPSYKAFTKEIVKKDSISQLNSLLEITSTIIKVTIPMVAILLYK
                     LLGIHGVLLLDGFSFLIAASLISFIVPVNDEVVTKDKMTIGGVLNDLKIGFKYIYSHK
                     TIFMIIILSAFVNFFLAAYNLLLPYSNQMFGEISDGLYGVFLTAEAIGGFIGAILSGV
                     INKTLSSKRLMVFLSCSGLMLMLSTPLYFLFQNFIILAFSPALFSLFISIFNIQFFSI
                     VQREVDTEFLGRVFGIIFTVAILFMPVGSGFFSVVLNPNNTFNLFIIGVSITILSLIF
                     STLLKRYDKNS"
     gene            1921..2142
                     /locus_tag="VYN42_001951"
     CDS             1921..2142
                     /locus_tag="VYN42_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1462970.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            2313..2453
                     /locus_tag="VYN42_001952"
     CDS             2313..2453
                     /locus_tag="VYN42_001952"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462971.1"
                     /translation="MIQMIYNDTSDRSGCHRKRAASEILMMTSSVMPWRRLIKDKREV
                     IF"
     gene            2635..>3961
                     /locus_tag="VYN42_001953"
     CDS             2635..>3961
                     /locus_tag="VYN42_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1462972.1"
                     /translation="MSNNVEIIKANPLVTRRNDNSGSLSRRVAAYCRVSSDSDDQKNS
                     YDSQVRHYREYISQHQDWILVDIYADEGISGTQVGKRQDFQRLISDCLDGKIDYIITK
                     AIARFARNTLDTLKYVRLLKDKQIGVFFEEENIDTLTMDGELLLTILSSVAQQEVENT
                     SAHVKKGLKMKMQRGELIGFQGCLGYDYNQDTKSISINEKEAKIVRYIFERYIDGIGG
                     RAIARELDELGYKTPRGLDHWQDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLINF
                     GEEDKYYIKNNHDAIISPEIFTQAQEIRLRRSGNKKTIANTNGKRERYSRMYPFSSRL
                     ECGFCGTVLSRRSWHSSSEYKKIIWHCTTSIKRGKKHCTHSKGIEEKAIENAFLQSYQ
                     QLFYENNNLTEDFLEIIKEELTDDTLKVELNKIVSKLNSLYKKEEKLVSM"
BASE COUNT         1385 a          512 c          708 g         1356 t
ORIGIN      
        1 aaaaatgatt attacgataa aagaaaatat tcataattaa ggagttattc ttgaaaatag
       61 ataaaaaaaa cgaggctttc cttattgtaa gtagaggcat atctcgaatt ggagatatta
      121 tgtttgactt tgcgaataat acctttcttg caggattaaa tccaacatct ttatcattgg
      181 ttgcagtata tcagtcacta gaaagtgtga taggtgttct ttttaattta tttggtggag
      241 tcattgcaga tagtttcaag cggaaaaaaa ttattattgt tgcaaatatc ttatgtggta
      301 ttgcttgtat aattctttca ttcatatcac aagagcagtg gatggtcttt gcaattgtca
      361 tcactaatat tatcttggca tttatgagtg ctttttctgg accgtcctat aaagcattta
      421 caaaagaaat tgtaaaaaag gatagtatat cacaacttaa ttcattgcta gagataacaa
      481 gtactataat taaagtaaca ataccaatgg tagcaatttt attatataag ctacttggga
      541 tacatggtgt tttactattg gatggattct catttctaat tgctgcatca ctgatttcct
      601 ttattgtacc cgttaatgac gaagtggtca caaaggataa aatgacaata ggaggagttt
      661 taaatgactt aaaaataggg tttaagtata tttatagtca taagacaata tttatgatta
      721 ttattctctc tgcttttgtt aatttttttc tagcagctta taatttattg ttaccttata
      781 gtaatcaaat gtttggagaa atttcagatg ggctttatgg tgtttttcta actgcggaag
      841 caattggagg atttattgga gcgatattaa gtggtgttat aaataaaacc ttgtcaagca
      901 aacgtttaat ggtcttctta tcatgttcag gattgatgtt aatgctatca acgccactct
      961 attttttgtt tcaaaacttc attattctag ccttttctcc ggcattattt agtctattta
     1021 tttctatttt taatattcaa tttttctcta ttgttcaaag agaagttgat actgagtttc
     1081 tcggtagagt ctttggaatc atctttacgg tagctattct ttttatgcca gttgggtctg
     1141 gatttttctc agtagtttta aatcctaaca atacttttaa tctttttatt attggtgtat
     1201 ctattacgat attatcgcta atattcagca cgctattgaa gaggtatgat aaaaatagct
     1261 gatatagaga atttagagcg cctttggaat atatttttgg aatttaatca atcacagttg
     1321 aatgtgaagg gcaatctgtt ttagaagaat acaatcaaga tatcattatg ctattacttt
     1381 agttcagtta aaatattgag aagtattact tttatttaaa aagcatcata aaggactcca
     1441 attaattttt aatgattttt ctaatctaat tttgtggtta ttgacaaata aagtctagtt
     1501 aattgctttg aaatccatgg attggtttat atacatctgt taatgcaacg gataatttta
     1561 ttgataagta gggagtggct attattcaac ttttaggttc tgaaagtaag agattcatat
     1621 tagaaatatc atgttgacca tttttcaatt tgctggttag tagtaatctg gacatcatta
     1681 atcccttcct taacaaaatt atgtgacttt tgttaccgga ttactgctga ttttttaata
     1741 gcttataaca tttttagacg gttaatagat tttgaccgtc tttcttaata ttgtcttacc
     1801 tataatagat atgcttatga gatatgttta ataaattaat tttagttcaa aatgtccagt
     1861 taggacactt tgaatgattt cttagtttta tatattatac ttttctcagg agaaagctag
     1921 atgtacagac gtttgagaga tttgagggaa gatcacgatt tgacccaaaa acaaatagct
     1981 aaaatacttt cgtttacaaa ctcagcttat gctaaaattg aacgaggtga gcatacgtta
     2041 acagcagatg tattggtaac tctctcaaac ttttacgatg tcagtacaga ctacctattg
     2101 gaattgacag attttcctga taaaattcgc tttagaaaat aatctcctca atttcataga
     2161 gtgtgaaaat gaggagatta ttttatttgg ttctttgaca attaaatagt ccaaaatggt
     2221 actttcctca tttgtggagc agttttgaat ggctcgccat gataagagcg acataaaaac
     2281 catcaataaa atagagcgat actttatatg ccatgataca aatgatatac aatgatactt
     2341 ctgaccgttc aggctgccac cgtaaaagag cagcaagtga aattcttatg atgacttcat
     2401 cagtcatgcc atggaggaga ttgataaaag ataaaaggga agtgattttt tgaaatcaaa
     2461 tttagaaaat tatatagtcg agctagagat gctaaatcta ttattcttaa aaaaacttat
     2521 tagcgaaaaa gaatatgaaa aaataaagct gaaactgcgt aaaatatata caaattagct
     2581 gacctttttt attggttgcg gtaaaataat tgcagagaaa taggaggttc agccatgtca
     2641 aataacgttg aaattataaa agcaaatcct ttagtaacta gaagaaatga taatagtggt
     2701 tctttatcga ggagagtagc agcatattgt cgtgttagtt ccgatagtga tgatcaaaaa
     2761 aatagctatg attctcaagt tcgtcattat agagagtata tatcacagca ccaagattgg
     2821 attttggttg acatttatgc tgatgaaggg atttcaggaa ctcaagttgg aaaaagacaa
     2881 gattttcaaa gattaatttc agattgcctt gatggaaaaa tagactatat cattaccaaa
     2941 gccattgctc gctttgctag aaatacatta gatactctca aatatgttcg tttgctcaaa
     3001 gataaacaaa ttggtgtatt tttcgaagaa gaaaatattg atactttaac tatggatggt
     3061 gagttactat tgacgatatt aagttcagtg gctcaacagg aagttgaaaa tacatctgcc
     3121 catgttaaaa agggtttaaa aatgaagatg caacgtggag aacttattgg ttttcaaggt
     3181 tgtcttggtt atgactataa tcaagataca aagtcgatat caataaatga aaaagaagcc
     3241 aagatagtac gttatatttt tgaacgatac attgatggta ttgggggtag ggcaatagct
     3301 agagaacttg atgaactagg ttataaaact ccgagaggtc tggatcactg gcaagataca
     3361 acagttttag gaattattaa aaacgagaag tataaaggtg atattctaat gggaaaaact
     3421 ttcactgttg accccattag taagagacgt ttaataaatt tcggtgaaga agataaatac
     3481 tacattaaaa ataaccatga tgcaataatt agtccagaaa tttttacaca ggcgcaagaa
     3541 attcgattac ggagatcagg aaacaaaaaa accatagcaa atacaaatgg taaacgagaa
     3601 agatattcaa gaatgtaccc ttttagcagt agattagaat gtggtttttg tggtactgtt
     3661 ctgtctagaa gaagttggca ctctagttca gaatacaaaa aaattatttg gcactgtaca
     3721 acatctataa agagaggtaa aaagcattgc actcatagta aaggaataga ggaaaaagca
     3781 atagaaaatg cttttttaca gagctaccaa cagttgtttt atgaaaataa taacctaact
     3841 gaagactttc ttgaaattat aaaagaagag cttactgatg ataccttaaa agtggagtta
     3901 aataagatag ttagtaaatt aaattcgttg tacaaaaaag aagaaaaatt agtttcaatg
     3961 a
//
LOCUS       DAVLUM010000106         3958 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLUM010000106 DAVLUM010000000
VERSION     DAVLUM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.106"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(110..1525)
                     /locus_tag="VYN42_001954"
     CDS             complement(110..1525)
                     /locus_tag="VYN42_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1462973.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1538..3376)
                     /locus_tag="VYN42_001955"
     CDS             complement(1538..3376)
                     /locus_tag="VYN42_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1462974.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDAPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3394..>3958)
                     /locus_tag="VYN42_001956"
     CDS             complement(3394..>3958)
                     /locus_tag="VYN42_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1462975.1"
                     /translation="IYINLTDHISSSIERYKEGIIISNPLRWEISKYYKEEFELGKRA
                     LQIIKKELGIELPIDEAAFIALHFVNANLENNFQESYKITEIIMGIEKIIQDFYCTEF
                     NQDSIDYYRFITHIKLFAHRLVENTTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQ
                     TEYNYLLTSSELVYLMAHIRRLTKNLD"
BASE COUNT         1327 a          788 c          524 g         1319 t
ORIGIN      
        1 tcccctataa aataaagaag tttagaattt aatgtcttcc aaacttcttt attccatatt
       61 taatgaaatg ccaccttaac cgtgataata gctagtcatc aataaaaaac tatttgaata
      121 aggattctcc atttgattca atcactcctt tataccaagt aaaggacatt ttcttatatc
      181 gattgaatgt gccatttcca tcatcatttc gatcaacata aatgagaccg tacctcttag
      241 aaagctgtgc agtggacata gaaacgcagt caatacatcc ccaagacgta tagcccataa
      301 tttccacacc atcttgtaga gcttcagcta cttgcaataa atgttctttc atatactgaa
      361 ttctataatc atcttggact gttaagttat taaattcatc ttttattagt tgatctttag
      421 cacctaatcc gttttccact ataaataatg gaatttgata acggtcataa tatctattta
      481 aaattatacg tagtccaatt ggatcaattt gccatcccca ctcagaagac tctaaataag
      541 gatttactaa accaccaata atattccctt ctcctgaatt atactgtgtt ggaagagcag
      601 attgagtcac actcatgtaa tagctaaagg ataaaaaatc tacagtataa ttttttaata
      661 actctgcatc ttcagctgca aactctatgt taatgtcatg ttccttaaaa tatctttttg
      721 cataattcgg ataataacct ctaacatgca catctgaaaa tagataattt agattctcat
      781 actcatgagt cgcccataca tcttttggat ttggagtcat tggataagct ggcatagcta
      841 ataccataca ccccacctta aactctgaat taatctcacg agcaattttt gtaaccaaac
      901 tcgaggcgac taattcatga tgtatagctt gatataattc ttgtttcgaa agattctcct
      961 taggtatatc tattcctcca ctagtaaacg gtaattccaa aacagagttt acttcgttaa
     1021 atgtaagcca atatttaact ttatctttat acctttctaa aactgttcga gcaaattttt
     1081 cataaaaatg aatcattctc ctatcaatcc atccatgata ttttcttgct aaatataatg
     1141 gagtctcata gtgtgaaaga gttacaagtg gctctatccc gtgagcatgt agttcatcaa
     1201 acaattcatc ataatatttc aaaccagctt cgttaggttc ttcttcatct ccttttggaa
     1261 aaattctact ccatgcaata gaagtacgaa aaacattaaa gcccatttca gaaaacaagg
     1321 ttatatcttc cttatattta tgataaaaat caatacctaa taattttaag ttatcttctg
     1381 taggattttc tgttgcttct cctaatccac ctttgggtaa cacatcctga actgataagc
     1441 ccttaccatc ttcattatat gctccctcta cttgattagc tgcaacagct ccaccccaaa
     1501 gaaaatcatc tggaaaaatg gtcataactt tcctccatta taatattacc agtagttcct
     1561 tagaatgctc gattgtctga ttattaggta atactaatac atctagaaaa tcattggtat
     1621 tcgttacaat tactggtgta actgtttcgt agcctttagt cttgattaaa tttaagtcca
     1681 tttcaaaaat caactgattt ttgaaaactc tgtctccttc ttctacatga ctaataaaac
     1741 cttgaccttt tagctcaaca gtatctaatc cgatatgaat tagtaactca acaccctcat
     1801 cactcttcaa tccaattgcg tgcttagtcg gaaaaatatt tgtaattttc ccatcaaatg
     1861 gtgcataaac cttaccttca cttgggataa tcgctactcc gtctccaatt agtttatctg
     1921 aaaatgtttt atcctgaaca tcgcttaacg gaatgatttc tcctgatata ggagaaaata
     1981 tcattttttt atttgaaact ccagcttcaa cttctaaatt actagaactc tcttcttcat
     2041 cgattccaaa tatataagct aatacaaagg taataacaac cgaaatgacc gccacaatta
     2101 aagcatttac aatatttgat ggtgcatcag aataaataaa ttgaggcaac gctatcaaag
     2161 atgggacagc aaatagatac gctttaacac tagtaagacc tgcaaataat cccgctaatc
     2221 caccaccaat catagctgca taaagcggtt ttttatattt taaagtcaca ccatataatg
     2281 caggttcggt aattcctgca agtaaggctg agaaacctgc tgcaaaagca atttgttttg
     2341 tattattatt tttactcttt aatgcaacag ccatcgaagc agccccttga gctaagtttg
     2401 accctaacat tgctggaaga attaatacgt ctggagtagc aatagatgcc gccaaaaaaa
     2461 taggtgcaaa agcccaatgc attccagtca taacaataaa tggcataata gcaccaagaa
     2521 tagctaatgt aagccatcca gctacaccat acatttgccc aactagattt gataatcctt
     2581 caccaacaat tactccaata ggtccgacta caactaaggc aatacagctt gatactaata
     2641 atactagcgt aggttgcaaa aaactcttag taacagctgg tgttaattta gcaatcattt
     2701 tttcaatata tttcatcaac caaaccataa taagaattgg aacgactgac gaaccataac
     2761 tagctggtgt cacaggtaca ccaaataaac taagaggatt ccctgattgc accatttgaa
     2821 caaaatttgg atggagaagt acacctgcta cagacatagc taatgtagat gttactttta
     2881 atttttgtga tgcagaataa gctaataaca gcggtaagaa ataatatgga gcatccccaa
     2941 aaaatgtcaa aaaagcaata gtctgagaat ctgattgcaa tataccaagc attggtaaaa
     3001 taattaccaa gactttcagc atacctcccc ctaacattgc tggaatgatt ggagtcatgg
     3061 aaccagcgat atactcaatg attctttcta aaatattccc tttgtgccct tgaacaactg
     3121 aatcggattc aaaattgcca agtttaacga attctttata ataattagct acatcattac
     3181 caagtataat ttgatattgt ccattctttt tcataatacc tattacacct ggtatcttct
     3241 tcacatcatc atcattgact aaattttcat cttttaattc taatcttaaa cgtgttacac
     3301 aatgggtaac tctattgaca tttttttcac ctccaattac atcgaggatt ttttgtacct
     3361 tatctttata actcatggta ttctcctatt ctattaatct aaattttttg ttaagcgacg
     3421 aatatgagcc atcaaataaa ctaattcact agaagtcagc aaataattgt actcagtttg
     3481 tataaacatt gccacctgtt caccacattc atattctcta ggatatttat ttttcattaa
     3541 tgctaacaag tcttcatcat catcgtcaca ataagttgta ttttcaacca agcgatgggc
     3601 aaataatttt atatgagtta tgaatctata ataatcaata gaatcttggt taaactcagt
     3661 acaatagaaa tcttgaatga ttttctcaat tcccataatt atttcagtga ttttatacga
     3721 ctcttgaaaa ttattttcta aattagcatt aacaaaatgt agcgctatga atgcagcttc
     3781 gtcaattgga agttcaatac ctaactcttt ttttattatt tgtaaagccc ttttcccaag
     3841 ttcaaattct tctttataat atttcgatat ttcccagcgt aggggattcg aaataataat
     3901 cccttcttta taacgttcta tgctcgaaga aatatgatcc gttaaattaa tatagata
//
LOCUS       DAVLUM010000107         3907 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLUM010000107 DAVLUM010000000
VERSION     DAVLUM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.107"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            371..598
                     /locus_tag="VYN42_001957"
     CDS             371..598
                     /locus_tag="VYN42_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462976.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VYN42_001958"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VYN42_001958"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1462977.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNNQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGIEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1333 a          647 c          864 g         1063 t
ORIGIN      
        1 gtcagtttca tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 attaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataatc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga atttaagcca
     1321 gatgccaagg ccccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattag gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tccatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aagaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga gggagaaaag gaagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaaaatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacacttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtatagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttca
//
LOCUS       DAVLUM010000108         3678 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLUM010000108 DAVLUM010000000
VERSION     DAVLUM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.108"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(84..617)
                     /locus_tag="VYN42_001959"
     CDS             complement(84..617)
                     /locus_tag="VYN42_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1462978.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(706..1482)
                     /gene="recX"
                     /locus_tag="VYN42_001960"
     CDS             complement(706..1482)
                     /gene="recX"
                     /locus_tag="VYN42_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1462979.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(1492..2268)
                     /locus_tag="VYN42_001961"
     CDS             complement(1492..2268)
                     /locus_tag="VYN42_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEV1462980.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVIIYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2325..>3678
                     /gene="rlmD"
                     /locus_tag="VYN42_001962"
     CDS             2325..>3678
                     /gene="rlmD"
                     /locus_tag="VYN42_001962"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1462981.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKVVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1153 a          661 c          690 g         1174 t
ORIGIN      
        1 ttattccttt ttgtgtttac acaatttatt ttatactacc aaaaaaaaca aggtcaggat
       61 tttgttcctg acctttgaca actttaccga ttctttagtt ctacatagcg cttgtaccaa
      121 atgtttacat aggcttctga gaaaggacca cgtccattgt taatccaatc aacaagaatt
      181 ttgacatgtt cttttaaaat atagtccaag tcatcagaat aattcatttt gcgtttgtga
      241 cgctcgtact cttcaacgtc caagagacgt ttttccccat ctgtaaaaat tttaacatcc
      301 aaatcgtaat caatatactt cagtgcttct tcatccagat agtaggggct agccatattg
      361 caatagtaag aagttccatt atcacgaatc atggcaatga tattaaacca atatttcttg
      421 tgaaagtaaa caatagccgg ttctcgagtg acccaacgac gaccatcact ttcggtaaca
      481 agtgtatgat cgttgacacc aataatggcg ttttctgttg tttttagtac catggtgtcc
      541 cgccaagttc ggtggagact cccatcatgc ttataacttt gaattgtaat aaagtcgcct
      601 tcttttggaa gcttcataac taaccaactt tctacaattt ataagtttat catttactat
      661 tgtaccataa aattacctaa aatctgtgaa tttcacttgg aaatattaaa gatattctct
      721 aagagcgctt gctatatccg aaaaatcgta gccctttcgt gctaaaactt gagttaaacg
      781 ctgcttcagt tcgtatcctt catactttcg agcatactta ctatattgtt tatcaagttc
      841 cttgaagatg agttcttgag tcgtttcttg gtcaacttgg ctatctaagt cgtcaaaggc
      901 aattttagca tcagaataag agaagccctt gttagtcaag ttctggataa tcttatcttg
      961 cagggcacga gatggaagtt ttccctcata ttttttcaat agtttattag ctacacgttg
     1021 agcaacttca gaaaaatcaa attctttcaa gttctcttct atagtagatt ttgaaatccc
     1081 tttttgagct agtttctgag tcagcacata aggacccttg tctcctgaaa gttgattggt
     1141 attgatgata gcataagcgt actgaccatc attaatccac ttatcttctt taagattagc
     1201 aataacttga gaaacgatgt ttttatcaat atcgtatttt ttcagatatt ctctgacttc
     1261 tttttcagtg cgtgctttaa aggataagtg gtagagagcg agattcttac cataagaaaa
     1321 ctgggcaaaa tcctgaatct cggtcagttc ctctttacta atgaccttat ctcgagacag
     1381 cataaaacgg acaatggtat cttccgtgat ataagaggtt tgctgtccat ctagttccat
     1441 caagtagaga cgttttttct tttcaagttt tgtgattttc ataatttcct ttcatctaaa
     1501 tgcttcgaaa gctgcaacaa gtcgtagttt atccatattt acatattctc taccgtaata
     1561 gtcgagaaat aattcagcat acgtagcatc ttgtaggttg taatgaaggg accaaattgc
     1621 ccaaaagagg tcgatatgtc ggtcactaaa accagccaat cccaagtcaa taaagcaaga
     1681 aaaatgagag gcatccttca agatgaaatt tggcaggcag gcatctccat gaataaaagc
     1741 atcagctttg agaatgtaac ctttctcttg tatcagttgg taagcttctt cacgactgtg
     1801 aatgtgaaat tgaggcagaa gagtcttgtt ataaaaagtc cccttctgat agttttttaa
     1861 ggctttttct ttataacgct tcagatgatt ttccgacgga aaagattgtg gtttaagact
     1921 gtgaagtttg tttaatgctt gagccagggt ttgacagagt ctttcgggtt gatttaaaaa
     1981 agcgagagcg ttgctgccaa tggcttcttt agtcagaagg aagtccttat ttgctgataa
     2041 atagataatc actggagttc ccaatccttc agtttcgaac caacttgcaa tcttagtttc
     2101 ttgagctaat ctgccttttt gatctatttt taaatagtaa cctgaatcta tatataggac
     2161 agttgcactt gaatgagaag aactatcaga gagattagct cccttgatat agcttcgtaa
     2221 ttgttcaggg aaatctagta tactaaagcg aggtgttttt gaattcatgc ttttattgta
     2281 acatattctt aaatatctta gaaactccat ggtataatag acatatgaat ctgaaagtga
     2341 aacaaaaaat accattaaaa atcaagcgca tgggaattaa cggtgaggga atcggctttt
     2401 accaaaaaac attagtcttt gtaccaggag ctctcaaagg cgaagatatc tattgtcaga
     2461 ttacttctat tagacgcaac tttgttgaag caaaattact gaaggtcaac aagaagtcta
     2521 aatttcgaat tgtgccatct tgtactattt ataatgaatg cggaggctgc caaatcatgc
     2581 acctgcatta tgataagcag ctggagttca agacggactt acttcatcaa gcgctgaaaa
     2641 aatttgctcc tgcaggatat gaaaattatg aaattcgtcc aactattgga atgcaggaac
     2701 caaaatatta cagagctaag ttacaatttc agactcgaaa atttaaaaat caggtcaagg
     2761 cgggcttata tgcacaaaac tctcactatt tagtagagtt gaaagactgc ctggtacaag
     2821 ataaggaaac ccaagtgatt gctaatcgct tagcagaatt acttacttat caccagattc
     2881 caatcacgga tgagagaaaa gttctaggtg tccgtactat tatggtccga cgcgcgagaa
     2941 agaccggaca ggttcagatt attattgtta caaaccgcca gcttaattta actcaattgg
     3001 taaaagagtt ggttaaagat ttcccagaag ttgtgacagt agctgttaat acaaatacag
     3061 ctaaaaccag tgagatatat ggtgaaaaga cagagattat ctgggggcaa gagagtattc
     3121 aagaaggtgt actcaattat gaattttcac tatcccctcg agctttttat caactaaatc
     3181 ctgagcaaac agaagtcctc tatagcgaag cagtaaaagc gctggatgtt gataaagaaa
     3241 accatttgat tgacgcttat tgtggagttg gaacgattgg atttgccttt gcaaagaaag
     3301 taaaaacact cagaggtatg gatattattc cagaagctat tgaagatgcc aagcgaaatg
     3361 ctaaaagaat gggatttgac aatactcatt atgaagctgg aacggcagaa gagattattc
     3421 ctcgttggta caaggaaggc taccgagcag atgctttgat tgttgaccca ccacgtacag
     3481 gtctggatga taagttatta gatactattc ttacttatgt accagaaaaa gtggtttata
     3541 tttcttgtaa tgtttcgacc ttggctcgtg atttggtacg cttagtagaa gtctatgatc
     3601 ttcattatat ccagtcggtc gatatgttcc cacatacagc tcgaactgaa gctgttgtaa
     3661 aattaataaa aaaagttt
//
LOCUS       DAVLUM010000109         3672 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLUM010000109 DAVLUM010000000
VERSION     DAVLUM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.109"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..506)
                     /locus_tag="VYN42_001963"
     CDS             complement(<1..506)
                     /locus_tag="VYN42_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462982.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQ"
     gene            complement(821..1879)
                     /locus_tag="VYN42_001964"
     CDS             complement(821..1879)
                     /locus_tag="VYN42_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462983.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(2684..2896)
                     /locus_tag="VYN42_001965"
     CDS             complement(2684..2896)
                     /locus_tag="VYN42_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462984.1"
                     /translation="MLVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(2904..3273)
                     /locus_tag="VYN42_001966"
                     /pseudo
     CDS             complement(2904..3273)
                     /locus_tag="VYN42_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
BASE COUNT         1362 a          667 c          464 g         1179 t
ORIGIN      
        1 tgttgattct caattctata aagtttttgt actaatgcta tgataataga aaatggaata
       61 agaggcaaaa gcaacggttt gtcatacaca aaagtaaaga aaaaatagta tgaaattagt
      121 gttgtaaagt acaagaagta gtaaaattta aacagattct tagttgtttg actctcctta
      181 taaaacactg ctattcctgg actaaatccc attagttggt gaaagagaat tcgatagtat
      241 ttcctagctc ctataatgat cacaaatata aaataaaaat aaattggtct taatttacaa
      301 aagattgagg aaactagtaa tagcaaagta tgtaagcatt gagacaaaat atagaataac
      361 ggtatcgcca atacaaaggt taagatggca tgagaggggg ttcctaagat gtccaatttt
      421 ataaatactg ggctgacaca aaatatcgtg cttataagca gtaaaatcat taaaattgtg
      481 tcaaaaaaat aacgcttatt tttcatttag tctactttcc attgttaaat aatactactg
      541 ctaacaccaa gccaacttag cacattgcat cacctaatcc tgcgctactt gtccataatc
      601 ctttaatgtt tctactaaaa ttattccaat ttcccccatc aagatagctt atttatccta
      661 gacaatgcct actgcaacag tataaataag attcatcagc catcttttct ggcaatcata
      721 tgagtagcct aatgatattt ctagttactc aaaaatatct agctatacta gagttatttc
      781 taatccctag gacacttgtt aatccaaatg taacaaattt tcacccctta ataggactct
      841 ttctggaaaa aatataaggt ctatctttat aaaaaaatct atcatattgg gatggcacgc
      901 atctggaatt taaacaagct ataaattcat ttataactac tatttgttta gaggcaacag
      961 catcttgtat accgccctcg aaagaaccat cttgtaattc cgaaatattt ttgtttaaat
     1021 attgttttga caaatctctt aatgcttcat tatcgtaaat gattcccaaa aatccaacct
     1081 tatatagtaa ataatttaaa cttacaaagt aattgaatcc catagtatat ttttctttat
     1141 aaagcaaagg taaaacttta taaaaaatat ctaagtcaac ctcactctga ttctgaagca
     1201 agtaggagtc aagcaaattt tcaaaaatag ctaacaatat gattggtgta aggtttttgt
     1261 attcacatgt caagtattcc gagtatcgtg cagatgatat ttcttttata taactttttg
     1321 aaagcaagat tttttcaaat tcatcatcta ttattaatct tctatttcca atccaagcag
     1381 tattaccacc caaataagat tgtacaaata gcaatatgta agagaacatg aacgtaaata
     1441 ctgaaagagg tagaattcta tgcgtaaaaa aatagacgat aatggtagcc aggagtaaag
     1501 ctatctctcg tgacaatcga attcttttca gcatcttttt taacagtccg taaggttgtc
     1561 cttggcaata ttcttgaact aaattaatcg gaatgacatc tctcaccatt tctggaaagt
     1621 agagtaagtt tataggttga aatctccagc tcccatcata agtaaatgga tatagaacca
     1681 aatacttaaa agattttttt cttataaact taattatcac aatatgaatg actgttgcaa
     1741 tgaagtatat taaatataaa agtaaaaccg ccatcaatat acttacaaaa atccccttgg
     1801 aatcaatcaa tggaaaataa aatattgcaa ctagaagcga ataaagtccc gctaataaat
     1861 atttctgatc atctttcatt caaaacacca tattatttac taagaataca tcagtacaat
     1921 agagcaattc tgtaagtcaa tatttgataa agcaaagctt taaacccttc cccagacgtc
     1981 agcttttatt caacccacta cagttgacaa ggagcccaaa ttattgataa aaactttagt
     2041 catcatcgtc tctataaaaa tattttctat acactcttga taataccaaa attaatgcca
     2101 atatcatacc aagagctata ataataaaat aacaaaaaat gaatttcacc aattcctgca
     2161 aaaaaatgtt tcatagctat agttttacgc ccataaatat ccatcaaatt taccgtctac
     2221 gatatctaaa ccatatgcaa tggctcctcc taatgagaaa acttcagcaa cagtagccgc
     2281 aatattaaga gcattagtaa tagttgccat actaactcca ccaatatatc ttgttatagc
     2341 acttagttac ctagataaga tatcctttag cttgcttcca aaatttaagt ctgcacctat
     2401 aatatgagtt catattagta ctgctaaatc ctatctatag taatgtaaaa cacctaaata
     2461 aagtcatctc tccaattcat tcaagaaatg aagaaaggca aaaaatcttt aaaataagaa
     2521 aaatgcatat tatcaggtgt tcaaaaatat tgatgatata cgttatatag atagaaagat
     2581 ttactcaatc tcactttcaa attgagtttt ttcccaacct cgtttttaat ttatatcttc
     2641 aataaaatct aatgacctag ttgatatgtc atatggaata atattattta atctgtaatt
     2701 tttttaaaaa acttaataat aaatttgctc cactgattgc tatcaatatt tcaattggta
     2761 aaaaatagta attccaaata aaatgagaaa tcagcaatga tagaaaaata acaatatcaa
     2821 ttttcctgtt gttgacatac tctgtaattt tatggtacag gaatgcaaca ataactgaaa
     2881 ttaaaacaac caacataaga ttattaacct attctcaatt gactatcacg tcgcccatcc
     2941 cagccatcaa taatattggt aaaaatccaa tcagctccag caccaattcc agcagatgca
     3001 atacttctaa taacagtatt tgcaaaagca tttccaatat gaattcctaa tactcctaaa
     3061 cctttaacaa tcccagctac cagtgcggag cgtaatccat aagatgcaag aactagttga
     3121 aggcctccac ctcctgctgc tgctaatgct gcatatgctg caccagtaat ggctcctgta
     3181 attgcccacc tgggtatata tagccccccc atcaaggtac atcatctctt cttcatcaat
     3241 cacaacataa ttatttggta atacaagttc catttatttt ctcctttttt attaagcatg
     3301 gttaggatgg tttcataaca agtgatcgca ggctttgttt agttacctaa attagacttc
     3361 cttcctttat cttattttaa atatttaaaa ccagttactg cttgaagctt aacagtttac
     3421 ttaattcaaa taacagctaa tcactgattc cctgatttta tcaaatatac taataacaac
     3481 aattgtgata cgatcatcat tataagaaca acatttaacg aatcaaagtt tttccgagat
     3541 aataataaag caacagcaag cagtattatt actaaagatt gaataactac tattactctt
     3601 aacattttat cctccactaa caactcaagc tcccttacat tatatcgacc agccccatgg
     3661 aaagattata gc
//
LOCUS       DAVLUM010000110         3373 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLUM010000110 DAVLUM010000000
VERSION     DAVLUM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.110"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..911)
                     /gene="phtA"
                     /locus_tag="VYN42_001967"
     CDS             complement(<1..911)
                     /gene="phtA"
                     /locus_tag="VYN42_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1462985.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHV"
     gene            complement(1165..2898)
                     /gene="ptsP"
                     /locus_tag="VYN42_001968"
     CDS             complement(1165..2898)
                     /gene="ptsP"
                     /locus_tag="VYN42_001968"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1462986.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(2904..3167)
                     /locus_tag="VYN42_001969"
     CDS             complement(2904..3167)
                     /locus_tag="VYN42_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1462987.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
BASE COUNT          885 a          729 c          641 g         1118 t
ORIGIN      
        1 acatggcgtt gactcaaagg cagtttgtag agctgtttca agagactatc aatgtcatta
       61 ctttgacttg cttgactgtt agtgttgctg ttgttgcttg tgttagtatt tgtagttcct
      121 ggattgctta cagaaggtac ccagtttgtt cttggagtgt tatcgctatt ttgtcggcga
      181 taggttcttg aatttgacag atttccccga ccagatagga aggcttctgc agcagctaac
      241 tcgctagctg ataactcatt cttaggaatg taatggtaat gatctccatg aggaacgata
      301 taagcatcac cagtatcctc tatgatatca gaagcattaa agatataacc atcatctgta
      361 gtatagcgtc cttgcgaacg tgccaaggca acagcaccat cgtttcttgg agtcccacct
      421 tcacgatgtt gactatgctc ttgtttttgt cgattgattt cctcttttgt acggacgtta
      481 tccgcgtggg cagcatcctt aaggtaaaca tagtattttc catctacctt gataacataa
      541 ccacccttga tttcactgat aatatcctcg tcttttagct ggtagtttgg atccttcatc
      601 agcaattctt cactgatgat agcgtcataa ggaaccttcc cattgtaata atgatagtgg
      661 tcgccatgtg aagtgacata gccttggtct gttatcttga tgacgatttg ctcagcattg
      721 attccttcac gcttgctaac ctcatcagga gtcaaattct ccgttttttg cgtcgcttgt
      781 tttccatcta tataggaaac acgattattt tccttaaccg ttctagcttg atacagtccc
      841 aactcgtaag aacaaacact taaaatcaaa gctgccgcag aaccaacaag gtatttctta
      901 ttaattttca tcgaaactct ctttctattt gatatttcta gttgcaattc atttctaaat
      961 tgcagaaact cctctctatt acttaactgg ttaatagttt actcctaaat ctccaacttg
     1021 tcaagaattt tatgaaccat ttaagtattt tttgttctga ccactacttt ttcaaggttg
     1081 gactttctat aagaaagatt ttcttgaaaa ttctttttaa aatatcaaaa aaatccctgt
     1141 aactgagttg cagggatttt tcgattaatc aaaattaacg tattcttttt gaagttcaag
     1201 aacttcttcc attgttgagc attctgtaag ggcacggttt gcgtactctt ccatcttagc
     1261 tgtgtcgagt ttcttcatca agctgcgtgt acgaagtaca gatgttgctg acatagagaa
     1321 ctcatccaag cccattccga caagaagtgg aacagcttgt tggtcaccag ccatctcacc
     1381 acacatacca gcccatttac cttcagcgtg agctgctttg atcacattgt taatcaagcg
     1441 taggattgat gggttgtatg gttggtaaag gtatgaaact tgttcgttca tacggtctgc
     1501 tgccattgta tattggatca agtcatttgt accaattgag aagaagtcaa cttctttagc
     1561 aaattggtct gcaagcatag ccgctgcagg aatctcgatc atgataccaa cttgaatgtt
     1621 atccgcaact gcaacacctt cagcaagaag gtttgctttt tcttcatcaa agactgcttt
     1681 cgctgcacgg aattctttca agagcgcaac cattgggaac atgatacgca attgaccgtg
     1741 aacagacgca cgaagaagag cacggatttg tgtgcggaac atagcatctc cagtctcaga
     1801 gatagagata cgaagagcac ggaatccaag gaatgggttc atttcgtgag gcatatcgaa
     1861 gtaaggaagt tccttatctc caccgatatc cattgtacga acgacaacag gtttaccgtt
     1921 cattccttca agaacagcct tgtatgcttc atactgctca tcttcagttg ggaagtcttg
     1981 agaatccatg tacaagaact ctgtacggta aagtccaaca gcttctgcac cgttgttgtt
     2041 aacaccttca acgtcttttg gagtaccaat attggcagcc aactcgaagt gtttaccgtc
     2101 agcagtcact gtttgagcat ctttcaaaag tgcccattca gctttttgtt tcgcataggc
     2161 ttcaccagct gctttaaatt ctgccgcttg ttcatctgtt gggttgataa tcacttctcc
     2221 agtgatcccg ttaacagcaa ggatgtcacc gtctttaacg atttcagtga tgttgtttgt
     2281 acctaataca gcagcaattt caagtgtacg tgccatgata gctgagtggc ttgtacgtcc
     2341 accaatgttg gttacaaaag cttttacaaa gtttttgtcc aattgagctg tatctgaagg
     2401 agtcaagtca tgcgcaatca caatcacttc ttcattgata gaagctgggt ttggcaattt
     2461 tttaccaaga aggtttgcca atacacgttt tgtcacgtcg cggatatccg ctgcgcgttc
     2521 ttgcatgtat gggttgtctt ccatgccttc aaagatagtg ataaacatat ctgtaacttc
     2581 tttcagacct gcttctgcat tcactttctt cgcacggata gtttccttga tttggctgat
     2641 catttctggg tcagcaagaa ccattaagtg agcatcaaaa acttgagctg cttcttcacc
     2701 gagcgtacct actgctttct cgcgaataac agaaagctcg tcttgtgatg cctgtagagc
     2761 ggcatcaagg cgagcttctt ctgcgtttgt atcttcgact gtaatagtct caaatgacaa
     2821 atccggctga acgagtagat atgcttttgc aactgcaaca ccgtcagatg ctgcgattcc
     2881 tttaagcatt tctgtcattt cccttatgcc aatccttctt tttccattgt ttctgagatt
     2941 gcagcgatag cgtcatctgc atctgcacct tcagctgaga tagttacgtc agcaccttga
     3001 ccaacaccaa gactcataac acccataatt gatttaaggt taactgattt acctttgtac
     3061 tcaagagtga tatctgaagc aaatttgcta gcagtttgta ccaacaatgt tgctggacgt
     3121 gcgtgaatac ctgtttctgc cactacgtgg aaatctttag aagccatagt ttgactctcc
     3181 ttttgttctt tctttttttg agttatatgt gataaccctt acaatttagt attataccat
     3241 cttctaggat ttttttcaag cattttctgg attttccttc aatttccttt cagataactt
     3301 gctgaaaatc ttctatccta gataacaaaa cacaggatat agtttcttca aaaacaattt
     3361 ataggataat cat
//
LOCUS       DAVLUM010000111         3364 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLUM010000111 DAVLUM010000000
VERSION     DAVLUM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.111"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..185)
                     /locus_tag="VYN42_001970"
     CDS             complement(<1..185)
                     /locus_tag="VYN42_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator BglG"
                     /protein_id="HEV1462988.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTE"
     gene            complement(485..3164)
                     /locus_tag="VYN42_001971"
                     /pseudo
     CDS             complement(485..3164)
                     /locus_tag="VYN42_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         1068 a          754 c          497 g         1045 t
ORIGIN      
        1 atctctgtaa aacgggtcat attatctcta tttttgagaa aaaaactttt ctcaatatca
       61 attggattta ctttatctcc agtttttctt ccaaaagcta tgccccttcc aaaaagaaga
      121 atatcgatat cttttttact ttgcgcaatt acggcattgt ggtttagtat tcgttttatg
      181 atcataaaat ttccctttta aaataaaagg aacctactta aaaacatcaa gaaacttctt
      241 ccgatgtgat taaataggtt cctgctcact tgtattagtg ataacatcct tttatttcaa
      301 tttttaatgg tgacatgaag cttaaataat taataactct gtaaccattt tcattttatg
      361 atatttcaat ctatttgtca agtacttgta gaaatttttt tattttgtgt gattcgaatg
      421 tgataatggc aacagtctca ctaaagaaat gaaaatcata catagaaatt tttaaaaatt
      481 ttctctatcg taaacctgcc actagttcag aaactatact agctgattcc aaacgtaata
      541 tggtcatctc atctaccttc cctaataatg gcattgcacc ataccaaaca atagtcttat
      601 tcaccaaaag aataggcgtt actatttttg attgagtaaa agacacttta attttctggc
      661 tcttcaactg gtctagccat gctttatttg caaccgtctc tggtatacat atctcaattt
      721 gactaatcct aaattctttt agaaaattca tcagttttgt ctggtgcaca taaggtaaaa
      781 taagcagaca ttcctgtctt tcccctgcta agtcctctct caacaccttc tcatatctac
      841 tatcaacata aacgaattgt ttctcctcac cctcgatgac acgataatcc atctttcgat
      901 aagctacttg tcgtttctga aacatctttt ctaaataagg aacatgaata tccacataat
      961 cgaaaatacg caccaaagac ttatccttgt agtttctatg aatccgacct gcatactgaa
     1021 ttaaattatt tttccaagaa aagggtgctg ccaagataag cgtgtccaac tgaggtaagt
     1081 caaaaccttc gccaatgtat tttccagtag acaacaaaac aaacccttta tctaactgtt
     1141 ctaacgtctc cagtaaactc gttctttctc ggactttggt ttttccgcta ataatgtaac
     1201 agtcatcaac ctctttctct ttcaataact tttcaaagac atctatctgt tgaattcgat
     1261 taactaaaac caagatattc cgtccttctg ccacttgggc tagaatatcc ttgagaatca
     1321 actgattcct cgctgagtct gtagcaatcc aatcactgag ctgtataaaa ttacttgctt
     1381 tggtcttttc aatctccaaa tgaccaaaag aagtgaatct taattgcaat tgccgtttaa
     1441 aatccgtttc cctcttatca gcagtatgga gtatctcacc aattctctga aaaacaatag
     1501 gctcatgacc attcttacgc tcaggcgtag ccgtcaaacc gtaaagatac ttccctctaa
     1561 actgagcaac aactttttca aacatcaagg cagagacatg atgacactca tccacaatca
     1621 tcatctcata ctcatccaaa agactttgac tattttccaa cttaaataga gattgaatca
     1681 taacgacatc aaccagttta ctcagccatt tcttagtccc accgtactgt ccaacatagc
     1741 cgattacctt ttcacgacct gatgccgtat aacggatagc ctcctcctct tcgaaagtca
     1801 aaaagcagtt taagcgatct agccattggt ctaagagttg cttattatgg actagaataa
     1861 ttgtttttgt tttccgttca gagataagag cagcacctaa aacggtcttc ccaaaaccag
     1921 tctccgcatg aagtaaacca ttttctttag aagtcatatc tgacagggct aactcttgct
     1981 caaaagtgag ttctccctta aattccacgc taatagacct ttgtaccttt ctcctatctt
     2041 ccacagatac ctgcttaaat ttatcttgca atggatacag caaacctctt ggcaaccata
     2101 aataatgatc ggattctcca aataaataca ttctctcagg aatttgatag gttggctgtc
     2161 gcatagcctg ctttaaataa aattcgggat tagaaaatga agccatattt ttcaagaaaa
     2221 acagtgtctt gggtgtcaca gacgattttt caagttggat catattggat aagacgatct
     2281 tcaactcctt gtccaattct tgcttgccta actcttcttg gattaacagt gccactttag
     2341 cagttgaaac cctctgaatt tcttgtagat acctccattg gtcttcataa ggctgaaact
     2401 gttcatccac aaagaccgtt cgcccttgat ggtaagcttc tccttgaaaa ggcaaggcaa
     2461 tcaaatttcc aaatcccccc cttaggaagg acatcctgat ttagaaacat gcgatcaaaa
     2521 gaatcaaagg acagttgcat actttcctgc attgccaatt ctaatagttt ctttccaaac
     2581 aagcgagcct ctcgactcgg aatagcttcc tcaaagaaga accaaatatg gagtccgtga
     2641 cccgaacgag aaatctctag atgggcttcc atctggcgtt ccctggctat tcttcgaata
     2701 gttaaaccag cttctttcca atctccttca tcaaaatcca gtaccaaaaa ataacagcta
     2761 tcatctaagt gcataggaaa gataccgata gctgtctccc cacgaaaatg agatttcaag
     2821 acggagtccg tcaatgtctg gaaactccgt ttttcaggtg gcaactgctt ccaaccataa
     2881 tcataggatg gaaagtactg aattttccct tgatcattga taaaactctt agcataaaca
     2941 tcataacggc cagcaaacac ggaggtaaac aattgtaatt tttcttgcgt cgtcaagtga
     3001 ctactttgaa gttggaacat ctcctcgaac caagagcgtt ccatcacaaa ctgactcttg
     3061 tctttaagac gtttacacaa gaaaaactca ctatccccat caaaagaaga aaagacatca
     3121 agtacttcta ccacaattcc atccaaagac acaaaaacag ccataaaagt cgcctccttg
     3181 attcctatag gctgattata acaagaatag ctgaaattgt acacgaaaat aaaatcctaa
     3241 tagtactcat tttgtatgtg gctaatattc cgtctcgctc cggaatgtac gaggtaaata
     3301 gagtttaaac gagcagtcta taaaattcaa aaaacgcatc atatcaggtg tacatgaact
     3361 acac
//
LOCUS       DAVLUM010000112         3228 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLUM010000112 DAVLUM010000000
VERSION     DAVLUM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3228
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.112"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(21..746)
                     /locus_tag="VYN42_001972"
     CDS             complement(21..746)
                     /locus_tag="VYN42_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEV1462989.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYYVDKTYQVEVNGLLTPDHIQAFQKRIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            908..2749
                     /gene="typA"
                     /locus_tag="VYN42_001973"
     CDS             908..2749
                     /gene="typA"
                     /locus_tag="VYN42_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1462990.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            2769..3023
                     /locus_tag="VYN42_001974"
     CDS             2769..3023
                     /locus_tag="VYN42_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1462991.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT          947 a          607 c          711 g          963 t
ORIGIN      
        1 gttttaaagc tttttttgtt ttatcgactc atctctaaat agtttttaat gatttgtaac
       61 tctttttggt tcaaagggcg gtagttacct tctgctaaat ctgggttcaa tgtgaagtcc
      121 ccaaattgga ttctcttgag gctagtcacc ttaacaccaa ccgagaggaa cattttcttg
      181 atttgatgaa attttccttc tgaaatggtg atagaggctt gactgaggga gggacttgca
      241 gatagaatct ctagttttgc gggtttacag acagtaccat ctaaaaagac aattctcttt
      301 tgaaaggctt ggatatggtc aggtgttaga agtccattaa cctcaacttg ataagtctta
      361 tcgacataat attggggatg gaggagttgg aagcccaagg gaccgttatc ggtcaagaga
      421 aggagtcctg ttgtatctcg gtccagtcgg ccgacggcat agagcttgtc agactggatg
      481 tcagatggaa gcaggtccat gacggtcgga agttccttgt ctttgttggc tgtaacgaca
      541 ccagcaggtt tatgaagcat aagataggtg tgttcatagc cttgaatgat tcgatcctga
      601 aaaaggagtt cttgtagtcc tgtatcgata ttttgggcta gggatcgggc tgggcaacta
      661 tcgacgagaa tgtccccttt gagtaaggct tgtttcatgg cctttcggct gattttttct
      721 tgagctaata aattatctaa acgcatactg tgcctatctt atcataagtc gcttgctttg
      781 aaaaggcttg acgtgaaaag aaaagcggag tgaaaacatt tacacttgct tgagttatgt
      841 tatttatttg aaattatggt ataatcgttc agttagaaaa taaattttga atattataga
      901 ggaaatcatg acaaaattaa gagaagatat ccgtaacatt gcgattatcg cccacgttga
      961 ccacggtaaa acaaccctgg ttgacgaatt attgaaacaa tcagaaacgc ttgatgcacg
     1021 tactgaattg gcagagcgtg ctatggactc aaacgatatc gaaaaagagc gtgggattac
     1081 catccttgct aaaaatactg ccgttgctta caacggaact cgtatcaaca ttatggacac
     1141 accaggacat gcggacttcg gtggagaagt tgagcgtatc atgaaaatgg ttgacggtgt
     1201 tgtcttggtc gtagatgcct atgaaggaac catgccacaa actcgtttcg tattgaaaaa
     1261 agccttggaa caagaccttg tcccaatcgt ggttgttaac aaaatcgata agccatcagc
     1321 tcgtccagca gaagtagtgg atgaagtctt ggaacttttc atcgagcttg gtgcagatga
     1381 cgaccagctt gatttcccag tggtttatgc ttcagcgatc aacggaactt cttcattgtc
     1441 agatgatcca gctgaccaag aagcgactat ggcaccaatc tttgacacga ttatcgacca
     1501 tatcccagct ccagtagata actcagatga gcctttgcag ttccaagtgt cacttttgga
     1561 ctacaatgac ttcgttggac gtatcggtat cggtcgtgtc ttccgtggta cagttaaggt
     1621 tggggaccaa gttacccttt ctaaacttga cggtacaact aaaaacttcc gtgttacaaa
     1681 actcttcggt ttctttggtt tggaacgtcg tgaaatccaa gaagccaaag cgggtgactt
     1741 gattgccgtt tcaggtatgg aagacatctt tgtcggtgaa accatcactc cgacagatgc
     1801 agtagaagct cttccaatcc tacacatcga tgagccaact cttcaaatga ctttcttggt
     1861 caacaactca ccatttgctg gtaaagaagg taaatgggta acttctcgta aggtggaaga
     1921 acgcttgcag gcagaattgc aaacagacgt ttcccttcgt gttgacccaa ctgattcacc
     1981 agataaatgg actgtttcag gacgtggaga attgcacttg tcaatcctta tcgaaacaat
     2041 gcgtcgtgag ggctatgaac ttcaagtatc tcgtccagaa gttatcgtaa aagaaatcga
     2101 cggtgttaaa tgtgaaccat ttgaacgtgt acaaatcgac actccagaag aataccaagg
     2161 gtctgttatc caaagccttt ctgaacgtaa aggtgaaatg ttggatatga tttcaactgg
     2221 taatggtcaa actcgtttgg tcttccttgt tccagcgcgt ggtttgattg gatactcaac
     2281 tgagttcttg tcaatgactc gtggttacgg tatcatgaac cataccttcg accaatactt
     2341 gccattgatt ccaggggaaa ttggtggacg tcaccgtggt gcccttgttt ctatcgatgc
     2401 tggtaaggct acaacttact caatcatgtc tatcgaagaa cgtggtacga tctttgtcaa
     2461 cccaggtact gaggtttatg aaggaatgat catcggtgaa aactctcgtg aaaatgactt
     2521 gacagttaac atcacgaagg caaaacaaat gaccaacgtt cgttcagcta ctaaggacca
     2581 aacagctgtt atcaagacgc ctcgtatctt gacacttgaa gagtctcttg agttcttgaa
     2641 cgacgatgag tacatggaag taacgcctga gtctatccgt ttgcgtaaac aaatccttaa
     2701 caaagcagag cgtgagaaag ctaacaagaa gaaaaaatca gctgaataag agctagaaag
     2761 agagaaagat ggtctattta gtcctaggaa ttttactgct cctactctat gtatttgcga
     2821 caccagaaag cattaaaggg actgtcaata tcgtcgctat ggtatgtatt ttagtggcac
     2881 tcttgatttt attggttcta tcttttctga aaatttttca attaccaaca gaaatattcc
     2941 tagcaatagc catgttgatt ctagcttact ttagtgttag agacatcaca ctcatgccag
     3001 ttaaaaaaag taaaagaaga taaaaaagag agtttcggct ctctttttgc taggaatttt
     3061 acaagattgc aatttatttt tgagttatca ccatctcttt tgtttggata atatgaatgg
     3121 gaaaaacttg aataaaattc tttaatggca tctattttat atttggttag tactggttgc
     3181 atattatttt gaaataaaac tactatataa tattattcat agaggtaa
//
LOCUS       DAVLUM010000113         3206 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLUM010000113 DAVLUM010000000
VERSION     DAVLUM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.113"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            239..2563
                     /gene="pflB"
                     /locus_tag="VYN42_001975"
     CDS             239..2563
                     /gene="pflB"
                     /locus_tag="VYN42_001975"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1462992.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(2701..>3206)
                     /locus_tag="VYN42_001976"
     CDS             complement(2701..>3206)
                     /locus_tag="VYN42_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1462993.1"
                     /translation="MNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTN
                     KEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPLFQTVFKTF
                     LKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSQA"
BASE COUNT         1002 a          631 c          641 g          932 t
ORIGIN      
        1 ttcgatttcc attgagtgtt actgcttatt ttcttttatt ataccctttt ttctgaaaaa
       61 aagaaaaaag gactttattt tttcaaaaat ataatacagt ttgaaataaa atatagactg
      121 ttttagaaaa gaaagtgtaa aaatagggaa ttttcacttg ttgaaatcgg ttactatatg
      181 gtatacttgt cttatgaatg taacagatga ctgttactag aaaaaagagg acattaatat
      241 ggttgttaag acagttgttg aagcacaaga tatttttgac aaagcttggg aaggcttcaa
      301 aggcgtagat tggaaagaaa aagcaagtgt atcacgattt gtacaagcta actacacacc
      361 ttatgatgga gacgaaagct tccttgcagg accaacagag cgttcacttc acatcaagaa
      421 aattgtagaa gaaactaaag cacactacga agaaactcgt ttcccaatgg acactcgtcc
      481 aacatctatc gctgatatcc ctgctggatt tatcgacaaa gaaaatgaag ttatcttcgg
      541 tatccaaaac gatgaactct tcaaattgaa cttcatgcca aaaggtggta tccgtatggc
      601 tgaaactact ttgaaagaaa atggatacga accagaccca gctgttcacg aaatcttcac
      661 taaatatgta acaacagtta acgacggtat tttccgtgcc tacacttcaa atattcgtcg
      721 cgctcgtcac gcacacactg taactggtct tccagatgca tactcacgcg gacgtatcat
      781 cggtgtttac gcacgtcttg ctctttacgg tgcagactac ttgatgcaag aaaaagtaaa
      841 tgactggaat gcaatcaaag aaatcgatga agaaacaatc cgtcttcgtg aagaagtaaa
      901 ccttcaatac caagcattgc aacaagttgt tcgcctgggt gacctttacg gggttgatgt
      961 tcgcaaacca gcgatgaacg tgaaagaagc aatccaatgg gttaacattg ctttcatggc
     1021 tgtctgccgt gtgattaacg gtgctgctac atctctaggt cgtgtaccaa tcgtattgga
     1081 catatttgca gaacgtgacc ttgctcgtgg tacatttact gaatcagaaa tccaagaatt
     1141 cgttgatgat ttcgttatga aacttcgtac agttaaattt gctcgtacaa aagcttatga
     1201 ccaattgtac tcaggtgacc caacctttat cacaacttct atggctggta tgggtaacga
     1261 cggtcgtcac cgtgttacta agatggacta ccgtttcttg aacactcttg acaacatcgg
     1321 taactcacca gaaccaaact tgacagttct ttggactgac aaattgccat acaacttccg
     1381 tcgctactgt atgcacatga gccacaaaca ctcttctatc caatacgaag gtgtaacaac
     1441 aatggctaaa gacggatatg gtgaaatgag ctgtatctca tgctgtgtgt ctccacttga
     1501 tccagaaaat gaagaacaac gccacaacat ccagtacttc ggtgctcgtg taaacgttct
     1561 taaagccctt cttactggtt tgaatggtgg ttacgacgat gttcacaaag actacaaagt
     1621 atttgatatc gaaccaatcc gtgacgaagt tcttgaattt gaatcagtta aagcgaactt
     1681 tgaaaaatct cttgactggt tgactgacac ttacgtagat gccttgaaca tcatccacta
     1741 catgactgat aggtacaact acgaagctgt tcaaatggcc ttcttgccaa ctaaacaacg
     1801 tgccaacatg ggattcggta tctgtggatt tgctaacact gttgatacat tgtcagctat
     1861 caaatacgct acagttaaac caatccgtga cgaagatggc tacatctacg attacgaaac
     1921 aatcggtgac tacccacgct ggggtgaaga tgacccacgt tcaaacgaat tggcagaatg
     1981 gttgatcgaa gcttacacaa ctcgtctacg tagccacaaa ctatacaaag acgcagaagc
     2041 tacagtatca cttttgacaa tcacatctaa cgttgcttac tctaaacaaa ctggtaactc
     2101 accagttcac aaaggtgtat acctcaacga agatggttct gtgaacttgt ctaaacttga
     2161 attcttctca ccaggtgcta acccatctaa caaagctaaa ggtggttggt tgcaaaactt
     2221 gaactcactt tctagccttg actttagtta tgcagctgac ggtatctcat tgactacaca
     2281 agtatcacct cgcgctcttg gtaagactcg tgatgaacaa gttgataact tggtaacaat
     2341 ccttgatggt tacttcgaaa acggtggaca acacgttaac ttgaacgtta tggacttgaa
     2401 cgatgtttac gaaaaaatca tgtcaggcga agacgttatc gtacgtatct ctggatactg
     2461 tgtaaacact aaatacctca ctccagaaca aaaaactgaa ttgacacaac gtgtcttcca
     2521 cgaagttctt tcaatggatg acgccttgga tgcattgagc taatcaagtt cttgaataat
     2581 aaaaaggaac cctcggtcaa acgactgagg gttttgtgct tgggatagta tgagcaattc
     2641 cttcggcgca atatgcaatg tttttgggct ctttgtcaac tgtagtgggt tgaaaaaaag
     2701 ctaagcttga gaaaggacaa atttcgtcct ttcttttttg atattcaggg cgataaaaat
     2761 ccgttttttg aagttttcaa agttccgaaa accaaaggca ttgcgcttga taagtttgat
     2821 gagattattg gtcgcttcca gtttggcatt agaatagtgt agttgaaggg cgttgacgat
     2881 tttctctttg ttctttagaa aggttttaaa gacagtctga aaaagaggat gaacctgctt
     2941 cagattgtcc tcaatgagtc cgaaaaattt ctcagggtct ttgttctgaa agtgaaaaag
     3001 taagagttga tagatctgat agtggtgttt caagtcttct gaatagctta aaatcttgtc
     3061 aagaatttct ttatttgtta agtgcatgcg aaaagtaggg cgataaaaac gtttatcgct
     3121 caatttacga ctatcctgtt ggatgagttt ccagtaacgc ttgatagcct tgtattcatg
     3181 agattttcgt tcaaactgat tcataa
//
LOCUS       DAVLUM010000114         3169 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLUM010000114 DAVLUM010000000
VERSION     DAVLUM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3169
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.114"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..410
                     /locus_tag="VYN42_001977"
     CDS             <1..410
                     /locus_tag="VYN42_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462994.1"
                     /translation="LQDYHEIWKLQSKSELPCVALSYISLIKPYLSESVREQIDLLEV
                     KRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKILEVRPDFVLIEQNIDDS
                     LNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            881..1255
                     /locus_tag="VYN42_001978"
     CDS             881..1255
                     /locus_tag="VYN42_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1462995.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            1463..2365
                     /locus_tag="VYN42_001979"
     CDS             1463..2365
                     /locus_tag="VYN42_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462996.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            2421..2774
                     /locus_tag="VYN42_001980"
     CDS             2421..2774
                     /locus_tag="VYN42_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1462997.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            2771..>3169
                     /locus_tag="VYN42_001981"
     CDS             2771..>3169
                     /locus_tag="VYN42_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462998.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKY"
BASE COUNT         1060 a          403 c          577 g         1129 t
ORIGIN      
        1 atcttcagga ttatcatgaa atttggaaat tgcaatcaaa atctgagttg ccatgcgtgg
       61 ctttatctta tatcagtttg atcaagccat atctttcaga gagcgtgcgt gaacaaattg
      121 atttattaga agttaagcga tttaaaaaaa taaatcatcc aatatcactt tatggtatgt
      181 tggatgttat aaaattaaat ctatatttac ggcattataa tgaaaaaaat aaatatgaat
      241 caatgttaaa gaaaatttta gaggtaagac cagactttgt tttaatcgag cagaatattg
      301 atgatagttt aaatagctcg caaccattat ctttatcttt agctatttca gaaatccaac
      361 ttttgcttga agtgtatata gggatcaaac atgtttcaat taggagataa aactagaata
      421 acatttgcta ttataggggc aagttgcata ttagtcagta tgtatcttat acctctcatt
      481 aacacggata ataaattttg ggaaatactt ttatttatat taggtgtatt gctaattgga
      541 attgcgttac taagtcaaaa aaaataaatt ttgtgtaagt gagtacgtaa ttattaatat
      601 tggctgtttt atggtggaaa gcatccatag cttttcgtaa aataatctga ttggctaata
      661 tttgcagtag gtgttgtcta tgataaagaa acctatcttg attggatttt agaactgtta
      721 agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa taaggtagag
      781 aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc acttgttagg
      841 aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg tattaccaaa
      901 taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat tttctattcc
      961 gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag gtggaggagc
     1021 aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta caagcgcaat
     1081 tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg caggatttgc
     1141 actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta ttacaacaat
     1201 ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt ggtaactaga
     1261 tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc tatttatatc
     1321 atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt tgattatttg
     1381 gattaatgtc gtttttttga ttttaatcat agcaatgata atttatccaa aattaagaaa
     1441 atgataagga cactgtaaaa ttatgatacg taaactaatc atttttttac taatgctccc
     1501 tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat tgaatctaga
     1561 atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga ttttatcaaa
     1621 aatagtttta gacatactat acgcattgaa agatttgtac aagaaagaag ctcttattac
     1681 gatttttcct tttattttta taggcaggaa gaaagtaaat gtgaggttct cgccctattt
     1741 ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta tatggagttt
     1801 tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg tcatcattat
     1861 gcttactaca atattttttt ggactataat ggatatcaat catctcgttt ttaataagac
     1921 ggaatttctt ttcaatcaaa ataaatggga aaaagaagat tcgtttgaaa gtgatttgac
     1981 aaatacgtta aaggataaaa tacaaaaatc agatctcagt tattctgact taatgtctct
     2041 tcagctgtat gatgcgatga atcaatccac ctttttaacg gatagtgaac tttttgagga
     2101 tattctgagt aaaattgaag attctcataa cacccttctg tgtacaggtc ttgtcgagtt
     2161 actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg ttgataaaat
     2221 tagaatacag ctcatcagaa taaatcaatt agattttttc tattatacaa gttggttaag
     2281 gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc ggaaattatt
     2341 actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg aaacaatttc
     2401 aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt gtgattgatg
     2461 aagaagaaat gatgtatctt gatggggggg cttatttaag caagagtgat tgtcaaggaa
     2521 tttgtgcagc tttagctatg agcccaggaa cttttatagc attagctgga tctgcagttt
     2581 taactaaaaa actaataaac tatattaagt ttggaggtct tggaggctgg cttattggtg
     2641 cagcagcagg tgtattggct acagcagcag gaaaaatagc ttactgtatt ggatatggtg
     2701 ctcttaatag aggttgtgat attagcggga acccttatcc ttgggatgga ttcatatctg
     2761 cgacagtaag atgaataatg tagataagat tcgaaaaata catattatcg tatgttggat
     2821 gtatatattt ttatcattca gggcgattat aaatgacacg gagtattttt tgcttatttt
     2881 tttagctttt atctactcaa tagtatcact acctctatat tctgtgaaaa ataaaatagt
     2941 atctatctgt ctagccataa attcgattct gttaatgagt ttccccattt taatcaataa
     3001 gtttttccca gaaagttttt tgacttatac cgtattaata agtgttttta tcctagagtt
     3061 agcaatcttt catttaattg gggaagattt tgctactaaa ttgactaacg aatataagaa
     3121 aattagtcag tttagaagca aggtgtctca atctccttgg ataaaatat
//
LOCUS       DAVLUM010000115         3064 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLUM010000115 DAVLUM010000000
VERSION     DAVLUM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.115"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(190..918)
                     /locus_tag="VYN42_001982"
                     /pseudo
     CDS             complement(190..918)
                     /locus_tag="VYN42_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(1178..1489)
                     /locus_tag="VYN42_001983"
     CDS             complement(1178..1489)
                     /locus_tag="VYN42_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1462999.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1504..2790)
                     /locus_tag="VYN42_001984"
     CDS             complement(1504..2790)
                     /locus_tag="VYN42_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1463000.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          915 a          673 c          537 g          939 t
ORIGIN      
        1 ttcaaaatat ctaagacatc gcttctttgt ttaatttgat aggctttgat acctaagctc
       61 cgactttatc acttaaaaaa taaaaaagac agctaatctc ttgcgcatca ggggatttcg
      121 ccattcttta atctcgttta agtgttgtat atggagcttt gcataatttt ttaaaactaa
      181 acaactacat taagcacgaa ctgtgacgct ggttccatct tccttataaa gattgataag
      241 cccctcttta agagctcgaa ccatgtctcc agcttgaaca ggttgtggga ctttaatagt
      301 caatagttcc attggatttg gagcgcggtc gattttattg cctttagcat catgcaaatc
      361 ttcaatatag gtttcaaaat gacggaaacc tggaccataa aactcaactt ggtccccttc
      421 gttaatgacg ttccgttgac gaatggttgc tgtttgtgcc gcatcatcat aagaaaccac
      481 ttcagcgaca aacttgtact cagggatttt acgacgagca ccaaacaact gctcattttc
      541 agatggtata ccgtagtaga aacctgttgc caattcacgt tgggcaacct tccacatctc
      601 gtccaccaag tcttgtttga tagcttcaaa cttttcagga ctttcaagat aggcatccac
      661 agccgccttg tagcagttgg ttactgttga tacatagtga atagactcca tacgtccttc
      721 gatttttaga ctgtccacac cattttcaat catatctgag atatggtcaa tcatagacat
      781 atcaacggct gacattgaaa attcttctgg aatctcaccc tgcaaactct tacgttcttt
      841 cccaaatggc atatcgtaaa ggtcgtactt ccaacggcat gactgagaac atccaccacg
      901 gttggcatca cgcatactct agacggattg ttttgacaat tctaaccttt tagactttgc
      961 ataataactg ttaaacagtc gaaaattacc ccagttttaa caagtagtca aaataccaga
     1021 taaagtaaaa aggggctagg aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt
     1081 attgaacaat cttgatatta tgcgttttat tgtgggaaga tttacttcat tttctcttgg
     1141 aattgagttt tctcctactt caaaactaga tgatttgcta tttaaaatag cgttccttat
     1201 gattttggca acctggatta aagcgagaaa aacaaaagag gcaacttaag ctttctttat
     1261 attgcttata tgttaatagt tttagacaaa caccacataa aataggctta tcctgtatca
     1321 aagataaggg ataaggctca aaagggtgat tttctaatga atcatgacac cgataacaag
     1381 cataatactt tttacaatca tagcattgta aagcaataat atccaacttg ctatggtaat
     1441 gaatgcatct tgtttgctta tccactaaga aaccctgtgc ctctatcatt tccttttcct
     1501 ttcttaagct cgaactgtga cgctggttcc atcttcctta taaagattga tgagtccttc
     1561 ttttaatgca cgaaccatgt ctcctgattg aacgggttgt gggactttaa tagtcaatag
     1621 ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca aatcttcaat
     1681 ataggtttca aaatgacgga aacctggacc ataaaactca acttggtccc cttcgttaat
     1741 gacgtttcgt tgacgaatgg ttgctgtttg taccgcatca tcataagaaa ccacttcagc
     1801 gacaaacttg tactcaggaa ttttacggcg agcaccaaac aactgctcat tttcagatgg
     1861 tataccgtag tagaaacctg ttgccaattc acgttgggca accttccaca tctcgtccac
     1921 caagtcttgt ttgatagctt caaacttttc aggactttca agataggcat ccacagccgc
     1981 cttgtagcag ttggttactg ttgatacgta gtgaatagac ttcatacgtc cttcgatttt
     2041 tagactgtcc acaccatttt caatcatatc tggaatatgg tcaatcatag acatgtcaac
     2101 ggctgacatt gaaaattctt ctggaatctc accctgcaaa ctcttacgtt ctttcccaaa
     2161 tggcatatcg taaaggtcgt atttccaacg gcatgactga gaacatccac cacggttggc
     2221 atcacgcata ctcatgtggt ttgaaagagt acaacgtcca gagtatgaaa tacacatagc
     2281 tccatggaca aaggcttcaa tttcaacatc tgtacgtttg cggatctcag ctaattcttc
     2341 cattgaaacc tcacgcgcta aaacgacacg agtcaagcct agctctttcc agaactcaag
     2401 ggtttcatag ttagtggcac tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc
     2461 agtcgctgca atcataatca aggctgggtc agatacgata actgctgcaa tcccaatatc
     2521 acgcagttta cggaaccact caccagcacc agcttcattt ccttcgtgca taaccatatt
     2581 agccgctaca tagaccttgg caccatactt ggccgcaaac tgcacgcctt cttccatctg
     2641 ttcgaaagta aagtttcccg cacggctacg aagaccatag gcctgaccac cgataaagac
     2701 agcatctgct ccatactgaa cagctacctt tagcttctct aaagtccctg caggtgataa
     2761 aacctcagga cgttttaatg tttttgtcat gatttctcct atttgcaata taaaagtttg
     2821 acatttttcc ttctcatttt atagtaaata aaggataaaa tcaagcctag acggattgtt
     2881 ttgacaattc taatctttta gactttgcat aataactgtt aaacagtcga aaattatccc
     2941 agttttaaca agtagtcaaa aagtctagaa aagtaaaaac cagtatccaa agatactgac
     3001 tcgtaaaaat acataaatta gtccttagat gactactccc actctgttgc tcctataatg
     3061 gaaa
//
LOCUS       DAVLUM010000116         3057 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLUM010000116 DAVLUM010000000
VERSION     DAVLUM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.116"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            185..2200
                     /locus_tag="VYN42_001985"
     CDS             185..2200
                     /locus_tag="VYN42_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1463001.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWFIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGEGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            2202..2834
                     /locus_tag="VYN42_001986"
     CDS             2202..2834
                     /locus_tag="VYN42_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1463002.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
BASE COUNT          933 a          549 c          636 g          939 t
ORIGIN      
        1 acaaggaaaa agaaaggggt ttcattgcat gagaaaaaaa cgtggaatta aaaaattagt
       61 tacatttgat gcgggatggt aaagaataat tgaagaagat tcttttatca atagtttagt
      121 aagcttgtta gtttatagag ggcaggggta tttctgccct ctgttttaga ataaggaatg
      181 cactatgaaa aaattattta tactcatatc caacctgctt gctagtttgt tctttgtttg
      241 ggtatttacc atttggactg atacatatgt ctcccattat taccccaacg ttgttgtacg
      301 tgattcttcc cctgaaacaa cttttcagca tgttgctaca cgcttggaaa aactagcaga
      361 agaaacagat agctttattg cgattcaaca ccaagatcct aactcagaag gtactacagt
      421 tttttcttat acgacctttg gggacggaaa gttgcctgat gggcttcagg aaaaaaatct
      481 agaagatgct caaagtagta gtgttgaaac aaactatttt gtattcgatg gacacctaga
      541 tattcacttg ctaagggaag agctaagtca acttggcttg actaacatgc acctgacaat
      601 tccatctaaa ctatctacgt taatggctat ctttagtaac ggatttcagt taatcagtct
      661 attgattttc atcttaacct ttgtagcact gactttaatt agtcaaatta gccaattacg
      721 gtcatcgggc attcgcctca tttcaggaga gaaacggtgg ttcattttcc ttagaccagt
      781 tggtgaggat ttgaaagcga tagctgttgg tttcagttta gctggcgtgc tcgccattct
      841 tatgcaaaaa attctgtcgc ttccaacgca atccctaatg accataggag aaggcttgct
      901 cagttataat ctcatcttgt tgtcgatctc cctgtttttc gctcaactct tcgcagttgg
      961 gataaaaaag atacacctga tgcagattat aaaagggcaa gtgcctgtca gaggaatcat
     1021 tagtttgatt ttaatcggtc aactattagc gattattatt gtaacgctgg gaatagggag
     1081 tagcttaaag tattcccaag cctggcaaca gcatcggatt ggacaagagg cttggagtca
     1141 ggaaagacaa ctgattaccc tatcaatcag ccgtgaagga acgagtcctg gttttgatga
     1201 acaagctcaa aggaaactca gaacttggta tcaattgatg gatctggctg tttcagaaca
     1261 aaaggctttc ttatctagac accagttaat tgaccgtact ttgcaaaatg gcatggcttc
     1321 ctccaaaaac ttgataacct ctacagaatg gcacgattac aacccgaatg gcaatgtcct
     1381 tatcgtcaca ccgcaatact tggagcgtca aaacattcct gtagatacaa ctattgagca
     1441 aaagatgaat caccttaatg taggggagtt tgtcttattg ctgcctgaac acctccgttc
     1501 agaggaagaa cattataaat ctgtttttga agacgactta accagtcgca tgtctagtca
     1561 agatgaacga cagcaaatga ctgctacggt aggttattta gaatcaggtc aggatcgttt
     1621 tgtgtataat acgaccccta tttcttacca gcagtttttg aaagatccaa tcatcattgt
     1681 tataacaccc caatcaactg gtccacagtc cattttgttt tggatagacg cagtacagaa
     1741 ctacgttctc tttaatcaat tgtctgatgc ccaggagctt atccagagac aaggcattga
     1801 aaattgggtc tcagaaatgc aaacaggtta ccacaactac atcacattat tggataatat
     1861 ccagagggaa cgttgggtaa tgctagcagg agctgtgctt gggattgcaa cttcaatctt
     1921 gttgtttaac actatgaata ggctctactt tgaagaattt agacgtgcca tttttatcaa
     1981 acgcattgca ggtctcaggt tcttagaaat ccatcgcact tatctctttg ctcaactggg
     2041 tgtgttttta ctgggatttg ttgcgagtgt atttcttcag gtagagatag gagttgcttt
     2101 cttagtcttg ttactcttta ctggtctatc tcttttacag ttacatgtcc aaatgcagaa
     2161 agaaaacaag atgtccattc ttgttttgaa gggaggttaa tatgattgaa cttaaacagg
     2221 tgagtaaatc ttttggagaa cgagagttat tttcgaatct ttcaatgaca tttgaggctg
     2281 gaaaagtcta tgccttaatt ggttcaagtg gtagcggaaa aacaaccttg atgaacatga
     2341 ttgggaaatt agaaccttat gatgggacga ttttttaccg aggtaaagac ttggccaatt
     2401 ataaatcgag tgattttttc cgtcacgaat tgggctacct cttccagaac tttggcttaa
     2461 ttgaaaacca aagtattgaa gaaaacctta agctaggtct cattggccaa aagttgagtc
     2521 ggtcggaaca gcggttgagg cagaagcagg ctttagaaca ggtcggcctg gcttatcttg
     2581 acctagataa gcgcatcttt gagttatcgg gcggagaatc gcaacgggtt gccttggcaa
     2641 aaattatctt aaagaatcca ccctttattc tggcagatga gccaacagct tcaatagacc
     2701 cagcaacctc tcagttgatt atggagattt tgctatctct tcgagatgat aataggctaa
     2761 tcattatcgc aacacataat ccggcaattt gggagatggc tgatgaagtg ttcacgatgg
     2821 atcatctgaa ataaaaatcc ttgtttttaa ttgcacgatg agttactgaa atattatcat
     2881 gaatcaataa ttggagttaa tttagaattg tactttatta atattgaggt aactttttct
     2941 tgataaagga ggaaatagtg gagaggaagt tagaatgaaa aaattcgaca attatattat
     3001 tgagaagcct tgcgattcta attcagataa actgcaaaaa atcttaataa ttgaaaa
//
LOCUS       DAVLUM010000117         3048 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLUM010000117 DAVLUM010000000
VERSION     DAVLUM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.117"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            357..833
                     /locus_tag="VYN42_001987"
     CDS             357..833
                     /locus_tag="VYN42_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1463003.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            833..1609
                     /locus_tag="VYN42_001988"
     CDS             833..1609
                     /locus_tag="VYN42_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV1463004.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLRVVEERHKELEGKNSYGI"
     gene            1599..>3048
                     /locus_tag="VYN42_001989"
     CDS             1599..>3048
                     /locus_tag="VYN42_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1463005.1"
                     /translation="MEFKKLVIENFRNFSSIEVALSNKNVIFGMNDSGKTNLLFAIRY
                     LLDRTIRNKGFIKSDYHRHDTSRPIKIQLELDLSDRKMEGDEESLKSSHSRLLISTVA
                     GARNNSSLDTFFISLEAVYNEKELFGNPVLSWGSTLDNLVEVPQYGTRSDIDKIFQIV
                     YVNPAIELDSFFKRNRRILFSDDSKTDEDVKLEEEIENNIEKLNENISNLHLITSVQS
                     QLTEAYKSYRKENLEIKIQSEISISGYLDNLTPYINWNDDTHNYPTSGDGRKKLLSYA
                     INHLISEKQYNKKVIIYLIEEPENSLHRSVQISLSKQLFVQNIYEYFFLTTHSAEVLY
                     EMDNTQLIKITNQQDATGQSVYYTVPNEFSNLKKKLNKSLAQSIFYDRILLVEGPSEY
                     YLFSAIFEYVSPNFEADGKYLLQVDGINFKPYSELYKALGIDFWIKTDNDLKASRGDK
                     HVFSPIGLNRCIDLLDHSATPILDNYRIDFSSK"
BASE COUNT         1105 a          414 c          560 g          969 t
ORIGIN      
        1 caacacttta ttgaggtatt ggatacgctt tgctaatagc ctaataatca catgtggagt
       61 gttgctacaa cgaaaaaggt gataatcctt gatttcaagc tattttataa gcattttgtc
      121 tttgtagata aaggcaattt tgacaataaa aatcctaaaa ggtgaatcgt tatagatgta
      181 tttgtagata tcgtttgcgc atcgaaaaaa ttaatacaag aataaatatt tatggctctt
      241 taggtgactt ttatagaagt aaagtttagg atagaaaaac aagaaataac gcaccatttt
      301 tggtgcgtta tgctttttta tgctataatg gatttataaa aataaaggag tttgctatga
      361 ttggaaagaa cataaaatcc ttacgtaaaa cacatgactt aacacaaccc gaatttgcac
      421 gaattatagg aatttctcga aatagcttga gtcgttatga aaatggaact agttcagtct
      481 ctacggaatt aattgacatc atttgtcaga agtttaatgt atcttatgtc gatattgtag
      541 gagaagataa aatgctcaat cctgttgaag attatgaatt gactttgaaa attgaaattg
      601 tgaaagaaag aggtgctaat ctattatctc gactctatcg ctatcaagat agtcagggaa
      661 ttagcattga tgatgaatct aatccttgga ttttaatgag tgatgatctt tctgatttga
      721 ttcatacgaa tatctattta gtagaaactt ttgatgaaat agagagatat agtggctatt
      781 tggatggaat tgaacgtatg ttagagatat ctgaaaagcg gatggtagct taatggaaat
      841 ccaagattat actgatagtg aattcaaaca tgctttagca aggaatcttc gttcactgac
      901 aagaggaaaa aagtccagta agcaacctat agcgattttg cttggaggtc aaagtggtgc
      961 cggtaagact acaattcatc gtattaaaca gaaagaattt caaggaaata ttgttatcat
     1021 agatggtgat agttttcgtt ctcagcatcc acactattta gaactgcagc aagaatatgg
     1081 caaagacagt gtagaatata ccaaagattt tgcaggaaaa atggtagagt ctttagtaac
     1141 aaaattgagt agtttgagat acaatctttt gatagaggga actttacgaa cagttgatgt
     1201 tccaaagaaa acagcacaac tcttgaaaaa taagggatat gaagtacaat tggccttaat
     1261 tgcgacaaag cctgaattgt cgtatctaag tactcttatc cgttatgaag aactgtacat
     1321 tatcaatcca aatcaagcac gcgcaactcc aaaagaacat catgatttca ttgtaaatca
     1381 tctagttgat aatacacgac aattggaaga actggctatc tttgaaagaa ttcaaattta
     1441 ccaacgagat agaagttctg tatatgattc aaaagaaaat acaacttcag cagcagatgt
     1501 tcttcaagag ttactctttg gggagtggag tcaggtagag aaagagatgt tgagggtggt
     1561 ggaagaaaga cataaagagt tagaaggaaa aaatagttat ggaatttaaa aaactagtaa
     1621 ttgaaaattt tcgtaatttt agttctattg aggttgcttt atcaaataaa aatgttatat
     1681 ttggaatgaa tgattcaggg aaaacaaacc ttctatttgc aataagatac ctcttggaca
     1741 gaactatacg aaataaaggt tttattaaat cggattatca tagacatgat actagtagac
     1801 ctataaaaat acaacttgag cttgatttgt ctgatagaaa aatggagggg gatgaagaat
     1861 cactaaaatc ttcacattct cgtcttctaa tttcaacggt agctggagca agaaataact
     1921 ctagcttaga tacattcttt atctcattag aagcagttta taatgagaaa gagttatttg
     1981 gaaatccggt attaagctgg ggctcaacac tagataattt agtggaagtt cctcaatatg
     2041 gtacaagaag tgacattgat aaaatattcc aaatagttta tgtaaatccc gctatagagt
     2101 tagattcctt ttttaagcga aatagaagga tattgttctc tgatgattct aaaactgatg
     2161 aggatgtaaa gcttgaggaa gagattgaga ataacattga aaaattaaat gaaaatattt
     2221 ctaacttaca tttgattact agtgttcaat cacagttgac tgaagcctat aaaagttatc
     2281 gtaaagaaaa tttagaaatt aaaattcaat cagagatatc tatttcagga tatttagaca
     2341 atctcacacc atacattaac tggaatgatg atactcacaa ttatccgacg tcaggagacg
     2401 gtcgtaaaaa gcttttatca tatgctatta accatttaat ttcagagaaa caatacaaca
     2461 agaaggtaat tatttattta attgaggagc cagagaatag cttacatcgt tccgttcaaa
     2521 tctctctttc aaagcaactt tttgttcaga atatttatga atactttttt ctaacgactc
     2581 attcagcaga agttctttat gaaatggata atactcagct cattaagata accaatcaac
     2641 aagatgcaac agggcaatca gtctattaca cagttcctaa tgaattttca aacttaaaga
     2701 aaaaattaaa taaatcgttg gctcagtcaa tcttttatga taggattctt ttggtcgaag
     2761 gtccatcaga atattatcta ttttctgcta tttttgaata tgtaagtccc aatttcgagg
     2821 ctgatggaaa atacttatta caagttgatg gaataaattt taaaccttat tcagagctat
     2881 ataaggcatt agggattgat ttttggatta aaactgataa tgatttaaaa gctagtcgtg
     2941 gagataaaca tgtattttct cctattggct taaataggtg tattgacttg cttgatcata
     3001 gtgcgactcc tatattagat aattatcgta tagatttctc ttcaaaag
//
LOCUS       DAVLUM010000118         3045 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLUM010000118 DAVLUM010000000
VERSION     DAVLUM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.118"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(89..961)
                     /locus_tag="VYN42_001990"
     CDS             complement(89..961)
                     /locus_tag="VYN42_001990"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1463006.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1198..2508
                     /locus_tag="VYN42_001991"
     CDS             1198..2508
                     /locus_tag="VYN42_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1463007.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(2874..>3045)
                     /locus_tag="VYN42_001992"
     CDS             complement(2874..>3045)
                     /locus_tag="VYN42_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1463008.1"
                     /translation="RTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTLSSGVTLI
                     TGKNGTGKSTLL"
BASE COUNT          913 a          697 c          505 g          930 t
ORIGIN      
        1 actatatttg aagaggcgtt taaactatct gacataaaac tcgttctaga ggaaagacat
       61 cctttaaaaa gttagtttat tttacaactt agacatcaag gtaggttaac cccttcatgg
      121 aaaaatcaag actcttagca ctatgggtta aactaccact ggagacgtaa tcaatcgcta
      181 aaccacgaaa acggctaata gtggtcatat caatatttcc agaacattca atccgagaac
      241 gtcctgcaat tagggtaatg gcctgttcaa tctgttccaa tgacatatta tccaacatga
      301 taatatcagc acccgccgcc gcagcttctt cggcagcagc aaggctttcc acttccacct
      361 cgaccatttt cacaaaagga gcataggcac gcgcttgagc aattgccttt tgaacactac
      421 ctactgccgc aatgtgattg tcttttagca tgatagcatc tgataaatta aagcgatgat
      481 tatagccacc gccaactctc acggcatatt tctcaaaaag acgtaaatta ggagtagttt
      541 ttcgagtatc aaatacctta atgcaatcat cgtctaaggc ttctacataa gcagctgtca
      601 tcgaagcaat ccctgataaa tgttgtaaaa aattcaaggc aacgcgttca catgttaaga
      661 gacttctcac cgagcctatg atttctaaaa ccaaatcgcc actagtcaaa cgatccccat
      721 ccttaaattg atgaggattc tggaaggtca cctcggcatc aaatagggta aaaacccttt
      781 taaaaacggt tagccccgct aaaacaccag cttccttggc aaaaagcgac accttggctt
      841 ggccatgatg atcaaaaatg gcattggtac tgtaatcttc ggaatgaaca tcttctcgca
      901 aggctgcttt caatgtatca tctatttgaa aaggggttaa atcagttgaa atgattgaca
      961 tcactaagtc ctctattttt aatatcactt gtaagcatta gaggcaatca ctattaactt
     1021 ccataggaaa tcacaagcct gaatacctca tttttaattc taacaagtgt caatacaatt
     1081 gtcaagacaa ttgtattttt tttgtgtata atagtcaagt accaatagga aacaggtggt
     1141 cttttgagcg ccaaaattgc caacctattt ccatattcta actgaaagga caattcaatg
     1201 attcatttaa taatgattag cgccattgct ctagccattg gaattggtta ccgcaccaaa
     1261 atcaatattg gcctgctggc tattgctttt tcttacctca tcgcaaccac tctcatggga
     1321 ttaagcccca aagaacttct tcatttttgg ccaacctcac tcttttttac catttttagc
     1381 gtctctctct tttataactt tgcaataact aacggtactc ttgatgtttt ggctcaacac
     1441 attctctacc gcacacgcac ctaccctaac gccctctaca tgattttata cctgatggca
     1501 acccttttgt ctgctttagg tgctggattt ttcactacta tggccgtttg ctgtcctcta
     1561 gcgattaccc tctgtcaaaa agcggacaaa caccctttga ttggagctca agccgtcaat
     1621 tggggagctt caggaggggc taatttgata accagtagct caggcattgt ctttcaaggc
     1681 ctgtttaagc aaatgggatg ggaagagcaa gctttttcac ttggcaatca tatctttatc
     1741 gtcagcatta tctacccact catcgtcttg cttttattat cctgttacag tcactatagt
     1801 aagggaaaaa caaactcatc cttgactatt gaccaaccac cactcctcag caaggttcaa
     1861 agacaaacca ccttgctcat gatcagcagc atggttttgg tttggctttt tcccttgttg
     1921 catctcattt tcccaaacat cgcctggata gctacttatc aaaaaacatt tgatattggc
     1981 tttgtctcaa tactcatggt ctgcctcgcc ttaaggctca aattagggaa gcaagaagcc
     2041 attttagcta aggttccctg ggctacaatt atcatgctct gcggcatgag cttactaatg
     2101 tctctagcgg tcaagtcagg tttagtcaca ctgatagggc acctcatgac aacaaccatt
     2161 cctcatttct ggttacctct gttcttttgt gtgatagccg gagtgatgtc actctttagt
     2221 tccaccctat ccgttgtagc tccaaccctc tttcccatca ttgctatcat cagtgctcaa
     2281 aatcctcaga ttgatattca cttactcaca acagccaccg ttattggcgc tctatctact
     2341 aatatctcac ccttttcatc agctggttct ctcattcaac tctcacttcc caatatagag
     2401 gaacgtggcc ttgccttcaa aaagcaaatt attctgggtg tccccatcag cttaagtttg
     2461 ggactcttga ccacctggat tctcatcctt ctagcttcct taagttagat ttattatcta
     2521 acttaagggt ggacttggta taataaagta gacacaaaat taagtggaaa cgaggaaaag
     2581 tcattatgcc aaaaaaaacc tttgataaag ccttcaaact ctctgctgta aacctcatcc
     2641 tgtaaaaatg attagttcaa ctttaaaaat tcatcccaat agtctttatc gatggattca
     2701 agaatatgaa aaatatgaag aaagtgcgtt cccaggacat gggagcgcac ttcgtcatac
     2761 tcaatttgaa atatagtgaa atgaaataag accaggacaa atagatcagg atagtcaaat
     2821 cgatttctaa caatatttta gaagtagatg tgtactattc tagtttcaat ctactatagt
     2881 aaagttgact ttcctgtacc atttttacca gtaattaatg tcacgcctga actcaaagta
     2941 tcaaaagaaa tattatcaaa caatatacga tgatccaccc tatacgaaat attttctact
     3001 ttcatttttt ctccttttga actaatagca aaagaaacag ttctg
//
LOCUS       DAVLUM010000119         3022 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLUM010000119 DAVLUM010000000
VERSION     DAVLUM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.119"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            18..1055
                     /locus_tag="VYN42_001993"
     CDS             18..1055
                     /locus_tag="VYN42_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1463009.1"
                     /translation="MIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAI
                     NDYNFNLLLIALPPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSIL
                     QYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYE
                     EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFID
                     PETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSG
                     VINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKI
                     EQFFAHIDALI"
     gene            1112..1909
                     /gene="psrA"
                     /locus_tag="VYN42_001994"
     CDS             1112..1909
                     /gene="psrA"
                     /locus_tag="VYN42_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1463010.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1920..2528
                     /locus_tag="VYN42_001995"
     CDS             1920..2528
                     /locus_tag="VYN42_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1463011.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETSSYPIYKIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(2476..3021)
                     /locus_tag="VYN42_001996"
     CDS             complement(2476..3021)
                     /locus_tag="VYN42_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1463012.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         1092 a          449 c          492 g          989 t
ORIGIN      
        1 gagaacttaa agagtatttg atagctagta cagcatttat tgttttggat actttactta
       61 acgaaacata tttgaaatat tatttattat cagataattt tatcaatcgt gttaataata
      121 aatctactgg aacaagttat cctgcaatca atgattataa ttttaatcta ttattaattg
      181 ctctcccccc actatccgaa caacaacgaa tagtagaagc aatcgaatca gctttagaaa
      241 aagtagatga atatgctgaa agttataata gactagaaca gctagataaa gaatttccag
      301 ataaactaaa aaaatctatt cttcaatatg ctatgcaagg aaaattagtt gaacaagacc
      361 caaatgatga atcagtcgaa gttttacttg aaaaaatacg agcagaaaaa caaaaactct
      421 ttgaagaagg caagattaaa aagaaagatt tggacatttc tattgtttcc caaggagatg
      481 ataactctta ttatgaggaa gtaccttgtg aaataccaga aagttgggaa tgggtgaggt
      541 taaacgatat aacctcctac attcaaagag ggaagtctcc aaaatattca aatattccta
      601 tataccctgt gattgctcag aaatgtaatc aatggtctgg cttttctatt gacttagcaa
      661 gatttattga tcccgaaaca gttcatagtt accagaaaga aagattacta agagatggtg
      721 atttaatgtg gaattcaaca ggtctaggta cgttaggacg attagctatt taccatgaaa
      781 ataaaaatcc ttatggctgg gctgttgcag atagccatgt tacagttata agagtcttat
      841 cgggagttat taattgccat ttcatctata attttctttc ctctcctatt gttcagtcag
      901 ttattgaaga aaaagcgtcg ggtagtacaa aacaaaaaga attattaacg aaaactataa
      961 aagaatattt aatccccctc ccaccccttc ctgaacaatc cagaatcgtt gataaaatcg
     1021 aacaattttt cgcccatatt gacgcactaa tttagtataa tagttttacg tgcggtggaa
     1081 tttctatcaa acataagata ggagttttac gttgaaagat tttgaattac atttgaagaa
     1141 agctggttta gctgaaaata ctgtgcgttc gtacctttat ggtgttcgat ttttcttgga
     1201 gaattacgaa ctcaaaatgg aagatttatt tgaatacaaa ggatatttat tagacaattt
     1261 taaacctaaa actgtcaatt tgcgactaca aggagtaaat aaatatctgg cttttattgg
     1321 tcatgatgat ttgaaattaa aatttgtcaa agtacagcaa aaaccatttt tagaagatgt
     1381 cattagccat gctgattacc tttttcttaa acgtagtttg aaaaaagatg gtattttaaa
     1441 atggcatttt gtcgtttggt ttttaggtgc aactggggct cgtgtaagtg aacttattaa
     1501 actaaaagta gagcatgtag aaatcggtta ttttgacatt tactcaaaag gtggtaaaat
     1561 tcgtagactg tacattccta aaaaattaag aaatagttgt cttagttggt tagaatcaga
     1621 aaatcgccga agtggttatt tatttttgaa taaatttaac gaaccaatta cagcaagagg
     1681 agttgctcaa cagttaaaaa attatgctga taaatacaaa atgaatccta aagtaattta
     1741 ccctcattct tttaggcatt tatttgctaa gaatttttta gcgaagtata atgatattgc
     1801 cttgcttgca gatttgatgg gacacgaaag tatagaaact actcgaattt atctaaggaa
     1861 aacagctact gaacaacaaa atattgtaga taaaattgtt aattggtaaa aaataacagg
     1921 tggtcaaact gactacctgc tatttttgtg attatggctc ttattatggg aacaaagacg
     1981 aaacatcctc ttatcctata tataaaatcc cagaagcatg gagatatatt aaatttgcta
     2041 gcctagttaa cttcagaata ggaaaaactc ctccacgcag tgaagctact ttttggggaa
     2101 ctgaaatacc ctgggtatct atatcagata tgcctatatc tggttatgta actaatacga
     2161 gagaatctat ttctaaatta gcattaaaat caaagaaaat agacatttca cctaaaggaa
     2221 ctttattaat gagctttaaa ttatctattg gaaaagttgc catattggat attcctgcca
     2281 ctcataatga agccattata tcgatattcc cctatgctaa taaagaaaat attatcagag
     2341 attacttaat gatatttttg ccacttatct ctactttagg tgattcaaaa gatgctatca
     2401 aagggaaaac attaaatagt accagtatct ccgaattatt aatccctatt tctaatcatg
     2461 aagagatgaa aagaatcatt tccaaagttg atttactttt tcaaaaagtt tctcaacttt
     2521 ttgagtaata agttcctgtt cctcaaaagg agctaacgga attaatagct cgcttagtgt
     2581 agttttagga atattatata aagcttgacc tgatagttta gttattgctt tcaattgttt
     2641 ataaaataac ggagaggaca agttaaataa tagaaatttt gaaataatct ctgaactttc
     2701 gaatggtgtt aattggaaaa taaatccacc agccacaaca ccatcatagt ctttatcgat
     2761 tcttgcaaac tttccaatat gttctaaaga ggttgataca ggtgttatta gctgattatg
     2821 ttttaaataa acttgctcag aggagatgaa ttgtgtatca atgtagtaat cattatccaa
     2881 cagagaaaat tctaaaggct taatattacc accacgtata attctaacac ctttattatt
     2941 aatgcttaaa tcgcccttct tgtaagaaag acctgtattc attgaaaaaa tatcttttat
     3001 ttttataaca acccaattca ta
//
LOCUS       DAVLUM010000120         2953 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLUM010000120 DAVLUM010000000
VERSION     DAVLUM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.120"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(105..2363)
                     /locus_tag="VYN42_001997"
     CDS             complement(105..2363)
                     /locus_tag="VYN42_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1463013.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPSISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2592..2822)
                     /locus_tag="VYN42_001998"
     CDS             complement(2592..2822)
                     /locus_tag="VYN42_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1463014.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
BASE COUNT          804 a          604 c          606 g          939 t
ORIGIN      
        1 attatatatc ataatggaca aagggcaagc tgtcaagaaa ttacagttat tttagtaaaa
       61 aaagaagcag aaaaatttca ttttctactc cttttctata ggatttattt ttctttttca
      121 gaacttttaa cttcagcttt tttggcagat ttaatctgaa tgtttccctt gctagtcata
      181 actgctttga gatctttttc gcttggattt tcaaggtagt agtcagtgat tgtgtcctca
      241 atatagtctt gaatagtccg acgaagtggg cgtgctccca tttttggatc ataacctagg
      301 tcaaccaact tttccttgac cttatcagtt acatccaaac gaatgttgtt gctagagagg
      361 cgcttgttaa catctgctag catgagctcg acaatctgaa ggaggttatc cttgctgaga
      421 gccttaaatt cgataatgcc atcaaaacgg ttcataaact ctgggctaaa gaagttaccg
      481 agttcaccga ggacagaatt ggtacgtcct tctctagcag caccaaatcc aacgctagct
      541 tcggtctttc ctgtacctgc atttgaggtc atgataatga tggcatcctt gaagctaacg
      601 gtgcgtcctt gcccgtctgt caaacgacca tcgtccaaga cttgaagaaa catgtgcata
      661 acatctgggt gagctttttc cacttcatcg agaaggatga gagaatatgg attgtggcga
      721 actttttcag ttaattgacc agcctcatca tagccaacat aacctggagg agcgccgacc
      781 aacttagcca cactatgttt ttccatgtat tcactcatat caaagcgaat catactatca
      841 gcagaaccaa aaagttcgat agccagttgt ttggaaagtt ctgtcttacc gacaccagtt
      901 ggcccaacga agaggaagct tccgattggg cggttagggg taccaagtcc gacacgatta
      961 cggcgaatag ccttggcaat cttatcgact gcatcatctt gaccaataac atgagacttg
     1021 agatcttcgg ctagatggat gagttgagat tgttctttct ctttcaaatc accaacaggg
     1081 atattggttt tctgctcgat aatgtgctca atagttttct cgctgatgct aggagtatcc
     1141 tggtctgtga tctttttctt ttgcatttcc ttatacttgg caatctggtc gcggaagtag
     1201 gccgccttct caaaatcttc ttctcgtgta gcttgagact tgagattttc agcctcaatc
     1261 aagcgctgat caattacttt aggatccaca aaattcaagg tcaagttcat cttagaacca
     1321 gcttcatcta ggaggtcaat ggccttgtca ggcaagaagc gatcttggat gtagcgattg
     1381 gaaagagttg cagctgcttc aatcgcagca tctgtatatt gaacgtggtg gtaatcttcg
     1441 tatttctttt gaatcccttt gagaatagtg attgtttcgt ccaccgttgg ttcatcgact
     1501 ttaacaggct gcatacgacg ctcgagggca gcatcctttt caatgatacg gtattcattg
     1561 agggtagtag caccgactag ttgcagttct ccacgagcaa gggctggctt gaggatattt
     1621 cctgcgtcca tattaccatc actcgcagaa ccagcaccaa caatttcatg gatttcatcg
     1681 ataaagagga tgatgtcttc acgtttgcga atttcttcca tgagtttttg catgcgttct
     1741 tcaaattgtc ctcgaatccc cgttccttga actaagctaa ccacatccag acggatgact
     1801 tgtttacctt ggagtttatg tggcacatcg ccatcgacaa ttttctgagc tagaccttcg
     1861 acaacggccg tttttccgac accaggttca ccgataagga caggattatt cttggttcta
     1921 cgattgagaa tctcgatgac acggataatc tcatcgtcgc gcccaataac ggggtcaatg
     1981 tctccacgac gggcaatttc agttacatta ataccaaatt cttccagcag gcctttttct
     2041 tggctaggtg gcggagtttg agcagatcca cgattttggg aaccataacc gccgtttcca
     2101 ccgtaacctc cacctgattg ggttggggga ataggaggag tattgctaga aggtctgaaa
     2161 ttgtttagat cattgaagaa atcaccaaag ggatcgaagt cacgattgtt cagatccgtc
     2221 atacctttga agaggctatt gttaggatct gttttgataa tcttatagca gttttgacag
     2281 aggtcaattt gtttttgttt tccattgaga ttggtgtaaa gatgaattgt tgagtcgtta
     2341 attttacagt tttgacaaag catacatcta cctcatttct ttctttagcc tgacttgttt
     2401 aaaggtcaaa aatagtcaaa ttctatactc tcattataac aggattgggg tgtaaagcaa
     2461 gtaaaaagat tgaagctttg agaagttgtt acaatgaaaa tttttgtgaa tttggactat
     2521 aaaaaaatcc tatttgtgag acaaaaagga ttttacttag acatgcaggg acaatcccag
     2581 cttgttttag attagtagag aagttcgtaa atttccattg cgattaagtc aatgctatca
     2641 aacgtatacg tttcgcgatc ttctacgtca cgaagggtaa agattgggcc gttttcttcg
     2701 tcgtggctgt acgcaacttc tgcaacaaca actccttcgc gttcaaaatt acgttttaaa
     2761 tttccgccat cgtttgccat tgcttcaagg cggttgatga ttctaaccaa atgtgattcc
     2821 attttgattc tccttcattt cttatcgtta ctattttacc ataaaggagg ccaacttgac
     2881 tagaaaaaac taagatttct cgctaattct gctagtttaa atatttttaa ataaattgga
     2941 taaaaaattt aaa
//
LOCUS       DAVLUM010000121         2902 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLUM010000121 DAVLUM010000000
VERSION     DAVLUM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.121"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..255
                     /locus_tag="VYN42_001999"
     CDS             <1..255
                     /locus_tag="VYN42_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1463015.1"
                     /translation="PNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPL
                     ALQNEFADFVAQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            315..551
                     /locus_tag="VYN42_002000"
     CDS             315..551
                     /locus_tag="VYN42_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV1463016.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            548..961
                     /locus_tag="VYN42_002001"
     CDS             548..961
                     /locus_tag="VYN42_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV1463017.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            1079..2044
                     /locus_tag="VYN42_002002"
     CDS             1079..2044
                     /locus_tag="VYN42_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1463018.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            2078..>2902
                     /locus_tag="VYN42_002003"
     CDS             2078..>2902
                     /locus_tag="VYN42_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1463019.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGREIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIYG
                     SGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL"
BASE COUNT         1065 a          409 c          574 g          854 t
ORIGIN      
        1 ccaaatctaa atcagaaatt tattatccat gttttaagga ataataatta tagtcgagtg
       61 atatcaggaa gtgctcagcc tcagttacca attacaaaat taaaaaaaat acttctcccc
      121 ctccccccac tagccctcca aaatgagttc gcagactttg tagcccaggt cgacaaatca
      181 caattggcaa tccaaaaatc tctggaagaa cttgaaactt tgaagaaatc tctgatgcag
      241 gagtattttg gctgatattc tgccattgta attacggtaa tgatttgtta taatacttca
      301 aaggaggaaa tcagatggta gtaaaaacaa gaaaacaagg aaattcaatc accattacga
      361 ttccaagtga atttaatatt ccaagtggtg ttaaatacga agcgaaattg ttaccaagtg
      421 gtgagattat ctttactcct gaagaattgg ggcagcaggt ttcttatgta tctgatgatg
      481 cctttgactt aaatttagat aaaatatttg acgaatacga cgatgttttc aaagctttgg
      541 tggaaaaatg acaatctatc tgacagaaaa gcaaattgaa aaaataaatg ctttagcaat
      601 tcaacggtat tctccaaatg agaaaattca aacagttagt tcttctgcct taaatatgat
      661 tgtgaactta ccagaacaat ttgtctttgg gaagtctctt tatccaacaa tttttgataa
      721 agcaacgata ctatttgtcc aattgataaa gaagcatgtt tttgctaatg ctaataaaag
      781 aactgctttc ttcgttttgg tcaaattttt acaattaaac ggctatcgtt tttctgtaac
      841 ggtagaagaa gcagtaaaaa tgtgtgtaac catcgcagta gaagctttaa ctgatgaaaa
      901 aatgacaagc tactccaaat gggtttctga acattctgtt agagaaaagg tcaaaaagta
      961 acctagtatg ctggatttga atgagcacaa gaaaataaat gaacagacaa tattagaatt
     1021 ctgtaatgca gaaactgata ttgtctcttt ttattgatga ataagaaagt gagaaattat
     1081 ggaatcaaaa gttacaatta tcatgcaaga aatgttacct cttttaaata atgaacaatt
     1141 actagcgttg agagagagtt tagaacatca tctagtagac ggaaaaaagc agcagaagta
     1201 ttcgaataat aacctgttgc aactatttat taccgccaag caggtagagg gctgtagctc
     1261 aaaaacaatt cgttattacc agaggacgat tgaaaacttg tttaatgcta ttaaagagtc
     1321 tgtgacacaa ctcacaacag atgatttaag gagttattta gcaaattacc agtctgaaaa
     1381 ggattgtagt aaggcaaatt tagacaatat taggcgtata ttgtcttctt tttttgcttg
     1441 gcttgagcaa gaggaatata tcattaaaaa tcccattcga cggataaaga aaattaagac
     1501 tgagcaaaat gtgaaggaaa cttatactga tgaacatttg gaaattatgc gtgataactg
     1561 tgaaaatttg agagatttgg caataataga cctactagca tcgacaggta tgcgtgtagg
     1621 ggagcttgta cagttgaatc gttcagatat tgattttgaa aacagagagt gtgttgtctt
     1681 tggtaaagga aagaaggaga gaccagtata ttttgacgct cggacgaaaa ttcatttaag
     1741 aaattatctt aacgacagaa aagatagtca ccctgctctt tttgtaacgt tagttggaaa
     1801 agtccagagg cttggaattg ctggtgtaga gattcgctta agaaagttag gagacaaact
     1861 cggtatacaa aaggttcacc cacataagtt cagaagaact ttagcgacta aggcaattga
     1921 taaaggtatg cctatcgaac aagtccaaaa actgctaggt catagcaaga ttgacacaac
     1981 cctggcctat gccatggtca atcaaaataa tgtcaagcat tcacaccaaa aattcatctc
     2041 ttaaaagcaa atcccgatat tccgaggagg tggttgcatg aagaaagtga aattagggga
     2101 agtggctact tttatcaatg gctatgcttt taaacctcaa gattggtcat ctgaagggag
     2161 agagattatc agaatacaga atctgactaa aacttcaaca gagataaatt attattcggg
     2221 tacgattgat aaaaaataca ttgttgaagc tggtgatatc cttatttcgt ggtcgggtac
     2281 attaggggtt tttcagtggt gtggaagatc cgcagtatta aatcagcaca tttttaaagt
     2341 ggtttttgat aagatagata tagataaatc gtattttaaa tatgttgttg aaaaaggttt
     2401 acaagatgct gtaaaacata ctcatggttc cacaatgaaa catttaacta aaaaatattt
     2461 tgataatatt atagttccat atacaaattt gggagagcaa caaagaattg caagtgagct
     2521 ggatttgtta agcaagctga ttttaaggag acaagaacaa cttgaagagc ttaatctact
     2581 tgtaaaatcc cgatttaacg agatgtttgg ggatgttatt ctaaatgaaa aagaatggaa
     2641 agttagcaaa tggaacgaga ttctaacaat aagaaatggt aaaaatcaaa aacaggttga
     2701 agatgctgat gggaaatttc ctatttatgg aagtggggga attatgggat atgctaaaga
     2761 ttggatagtg aagaaaaatt cagttattat tggacgtaaa ggaaatataa ataaacctat
     2821 tttagttaga gaaaattttt ggaatgtaga tacagcattt ggattagagc ctgttttaga
     2881 aaaaataaac tcagaatatt ta
//
LOCUS       DAVLUM010000122         2887 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLUM010000122 DAVLUM010000000
VERSION     DAVLUM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.122"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(79..540)
                     /locus_tag="VYN42_002004"
     CDS             complement(79..540)
                     /locus_tag="VYN42_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1463020.1"
                     /translation="MGKERREQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(507..650)
                     /locus_tag="VYN42_002005"
     CDS             complement(507..650)
                     /locus_tag="VYN42_002005"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV1463021.1"
                     /translation="MAYSTDFKQGALDSIKGGHRHVEAAKVFDVGVRTLFTWEKKDVS
                     KGT"
     gene            920..1300
                     /locus_tag="VYN42_002006"
     CDS             920..1300
                     /locus_tag="VYN42_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1463022.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            1399..1620
                     /locus_tag="VYN42_002007"
     CDS             1399..1620
                     /locus_tag="VYN42_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1463023.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            1637..1951
                     /gene="trxA"
                     /locus_tag="VYN42_002008"
     CDS             1637..1951
                     /gene="trxA"
                     /locus_tag="VYN42_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1463024.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            2256..2789
                     /gene="queF"
                     /locus_tag="VYN42_002009"
     CDS             2256..2789
                     /gene="queF"
                     /locus_tag="VYN42_002009"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1463025.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT          897 a          607 c          542 g          841 t
ORIGIN      
        1 tttttataaa gacacgcaaa tgagtataaa tcagctaatt tttggtttgc attcctattt
       61 ttatgcataa ttattctgtc attctctaat ttgtgaatca atatatctga ttagaaaact
      121 accattgagt ttttgctcca cctcattagt ccgctcaaaa cgccgtccgc taatcttgtc
      181 atagactttc tcccctctag gagcccctgc ataaggacga tagaggtagc ggttgattcc
      241 cgtttcgtca atatatagga ctggtaaatc ttttaggtta tccaaaatat caagaaactc
      301 agaaactttc tcaggctttt gttccctaaa actggtcgtc ttttttaaaa tgaccttaat
      361 ctgctttaaa actgcccata cggagggcaa agcacaatca aaacgggccg caatttcccg
      421 taaaaaagcg tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg
      481 ctttttgacg actcgctttt tccgctctaa gttcccttgc tcacgtcttt cttttcccac
      541 gtgaagagag ttctgacgcc gacatcaaaa actttggccg cctcgacatg tctgtgccct
      601 cctttgatgg aatctaatgc tccttgttta aaatcagtac tatatgccat agctttatta
      661 gaccatgctt attttaaact aagcaactat agatagagaa atgaaataaa atctgaattc
      721 gaatgtgata aggagttaga aattgaaaca ataggattcc cccattattc acacaaaaat
      781 aaaaccacta aaaaacagag cttgccagca ttcttgaaaa gtagtataat tattgcatgc
      841 gcaatcatct tgtgacgcag agactgcccg ttaatggact ttcttctata attatgactc
      901 taaaaagaaa ggagacacta tgacctattt ggaaaaatgg tttgacttca atcggcgtca
      961 gaaagaaatt gaaagtctct tggaagagac cattgcccaa cagagcgagc aaagtctgac
     1021 cttgaaagag ttctacctgc tctactatct ggacttggct gaagaaaaat ctctacgcca
     1081 gattgacctg ccagataagc ttcatctgag cccgagcgca gtttctagga tggtggctcg
     1141 cttggaagct aaaaattgcg gtctactcag tcgcatgtgt tgccatcaag atagacgctc
     1201 tagttttatc tgcctgacaa atgatgggca aaagacactg gcctcgctac aaaagactgt
     1261 cgaagaaagc ttggaagcag gtttggattt cttgatttaa gatgatttta aaaaaagttg
     1321 cgtgcgcaat catttttctt gacattctct tttataagga gtaaaataaa gttagcatta
     1381 aacaaaggag ttttaaacat gattgaaatt acctatatag atgccagcaa gaacgaaaga
     1441 actgtgactt tcgagtctta tgaagacttt gaacgttcgc aacaagcttg ccttatcggc
     1501 gtcgcagact actaccctgt ccaaaaatta acttacaagg gtcataattt ggactaccat
     1561 gggacttatg gagatatctt cttctatctc atgaaacaag atttaagcca atataactaa
     1621 aaaaaggaga aatacaatgg caaaagcaat tacagatgca acattcgaac aagaaacaaa
     1681 agacggtttg gtcttagtag acttctgggc aacttggtgt ggtccatgtc gtatgcaagg
     1741 tccaatcttg gacaaattgt ctgaagaact ttcagaagat gtcttgaaaa tcgttaaaat
     1801 ggacgttgat gaaaatccaa acacagctcg tgcttttgga atcatgtcta ttccaactct
     1861 tctcttcaaa aaagacggcc aagttgtcaa acaagttgca ggtgttcaca cagcagaaca
     1921 aatcaaggcc atcattgctg aattgagcta atcaaacgag agaccaagta ctttctttgg
     1981 tctctttttt cttgtccttt gccatttttc aaaaaatatg ctagactata gttgattgac
     2041 actagaatag tacacctcta cttctaaaac attgttagaa atcgatttga ttgtcccaat
     2101 cggtttgtcc tgttcttatt tcattttact atataagtag aatattacga tgtttgggat
     2161 atgtcatcgc taaaaaaact cgatttggta ttttttagct ccctaatggg agctttttgc
     2221 gtgctctgaa catttcccat tttagaagga gtactatgaa acgtcaatca gccttggtcg
     2281 tctttagtgg tggtcaagat tcaacaacct gccttttctg ggccatgcaa cactatgaaa
     2341 cagtcgaagc tgtcaccttt gcctacggcc aacgtcatca cctcgaaatt caaattacta
     2401 gagaaatcgc taaggaacag ggcattcgtc accatatcct cgatatgtct ctgctgggac
     2461 aaatcactgc tcagccagac tttgcgacga ttcatatttc ctacattcct gacaagctct
     2521 gtgtcgagtc aaaatccctc aaactatatc tatttagcta ccgaaaccac ggagatttcc
     2581 acgaaaactg tatcaacacc atcgggaaag acttggtcaa cttgctagac cctcgctatt
     2641 tagaagtctg gggaaaattc actccgcgcg gtggcatttc aatcgacccc tactataact
     2701 acggtaagca aggaactaag tatgagggct tggcagaaca acgcctcttc caacacgacc
     2761 tttatccaga gaaaattgac aaccgctaaa gtcatactca atgaaaatca aagagcaaac
     2821 taggaagtta gccgcaggtt gctcaaagca gtgtttgagg ttatagataa gactgacgaa
     2881 gtcagct
//
LOCUS       DAVLUM010000123         2877 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLUM010000123 DAVLUM010000000
VERSION     DAVLUM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.123"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(98..535)
                     /locus_tag="VYN42_002010"
     CDS             complement(98..535)
                     /locus_tag="VYN42_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1463026.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(576..1583)
                     /locus_tag="VYN42_002011"
     CDS             complement(576..1583)
                     /locus_tag="VYN42_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000231692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1463027.1"
                     /translation="MVFNPLYTFWIDYVKFFYRPYYSCRKIFKEEDSINHRKASYINT
                     QDNNYNKHIKDYFSMVDNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILL
                     KKIFDVGLRKGYYSSNPAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFT
                     VLFFTGLRLGEALALTWQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINK
                     KLSQELQDWEKRQKHLLEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSILKK
                     IRIHDFRHSHASLLINQGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDL
                     L"
     gene            complement(1869..2636)
                     /locus_tag="VYN42_002012"
     CDS             complement(1869..2636)
                     /locus_tag="VYN42_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HEV1463028.1"
                     /translation="MTNTAKKLTILSANLNFYMSNKVQKKTSEKIVKMLLSEEQNPKP
                     TFIALQEVGNRVIYKVEKDEIEDYSVNIERIENKLFNEGYGVIRPKQYGKEKDASNPV
                     NTRLFYLKKSVESIKELTPLGLGIKEDFYNRQCGGIFTINNQTIAVYSLHFKWQKDER
                     GAFWKKYIEIAESNKYNHLILAGDFNESLINVTTELSDKITKMKNYMVDASHDLPTWK
                     DKQLDHIFITPNTKIENYSTLDNDFSDHKALQVTIIV"
BASE COUNT          829 a          460 c          432 g         1156 t
ORIGIN      
        1 tatgccagtt cgagaccgac cgccagtata gtaataaaga caaagtttat aagccttgtc
       61 ttttgttttc tctttataaa attttatagt ttagttacta actttttttc tttgctctta
      121 aaaatctaat agcagaactg tatttcttat ttctctctaa gtctttttca gtaattaatg
      181 gtagtcttgt taaatctgaa ttatgccgta aatccgccaa ctttacaact ctagcgagtt
      241 catttttctt tactagattg agataagatt gataatcttg tccttttttc tttgtgagta
      301 tatcaacggc ttctataatg ttttttgaaa aaccttcctt ttttaggtct agtagggtta
      361 gtgaagtatc ttcaattaca tcatgtagat aggcgacagc tttctcttca tcagttgcga
      421 caaaactagc tactgtttca gggtgtttaa tgtagtcaat tcctgctcta tcaatttgtc
      481 caaagtgtgc ttttttagct acttcatgtg cttttattac ttgtgatgta tccatgattt
      541 aattataaac tttccattta taaaactcaa ttactttata gtaaatcatc tagtttatca
      601 gctaaatcct tttgcttact tgggtacaag tgagagtagg tatcaatcgt ggttgttata
      661 gaagcatgtc ctagtcgctc ttttacaact agataatctt ccccttggtt aatcagcagg
      721 gaagcgtgtg agtgcctaaa atcgtgtatg cgtatctttt ttagtatgct atcacgttca
      781 atgattttct tgtactgctt ttcaatagca ttttttgtaa ttgtgatagg actattttga
      841 aacacttgta atgttaggct attgttggta aattgctcta atagatgttt ttgtcgcttt
      901 tcccaatctt gtaattcttg gcttaatttt ttattgataa caattcttct tgttcctgct
      961 ttagtttttg ttgtgctgat atgagttact cctttattaa catagacaga cttcgtgata
     1021 tgaattgtat tacttgaaaa gtcgatgtct tgccatgtta gggcaagagc ttccccaagt
     1081 cttaatcctg taaagaatag aacagtaaag agtagtttga tattgtattc ttcgggttca
     1141 aatagtgtca aaaacttctg aaattctttg actgtccaaa attgcatttt tgttttttca
     1201 attggcaact tttttattaa ttttgctgga ttggaggagt aatagccttt tcgcaaacca
     1261 acatcaaaaa tttttttgag taaaatcatg attttgttaa tagtatttgt gcttaacggt
     1321 ttatcagaat ttttagctac tttttgccta agatgttctc taaattggta gatgtcttca
     1381 taggttagtt ttccgacatt atcgaccata gaaaaataat ctttgatgtg tttgttgtaa
     1441 ttattatctt gtgtattgat atagcttgct tttcgatgat ttatactatc ttcttcctta
     1501 aaaatttttc tacaagaata ataaggcctg taaaaaaact tgacataatc aatccaaaag
     1561 gtataaaggg gattgaaaac caagtattta tcaataagag gcccactaac aattcagttc
     1621 ctattctact aagaaaaagt ctacgagaag taataacata gggattaact tttactttca
     1681 cagatttgct cagtttcagt attttcatct tcattcctct cagaaattaa tgtatctata
     1741 caaccaatta aaaagataaa tggattttaa taaggtcagg ccctctaata tttgcaatac
     1801 tagtaataat ataagttttg gttaaaactg caacggttct aattttaaat aatttcattt
     1861 cggaactcct aaactataat agtcacctgc aaagctttgt ggtcactgaa atcattatcg
     1921 agagttgaat agttttcgat tttggtattt ggtgtgataa aaatgtgatc aagttgttta
     1981 tccttccatg ttggtaagtc atgactggca tctaccatat aatttttcat ttttgttatt
     2041 ttgtcagaca attcagtagt tacattgatt aagctctcgt taaaatcgcc cgccaaaata
     2101 agatgattat acttgttaga ctcagcaatt tcaatatatt ttttccaaaa tgcacctctt
     2161 tcatcttttt gccatttgaa atgaagagag taaactgcaa tagtttggtt attgatagta
     2221 aaaataccac cacattgtct attatagaaa tcttctttta ttcctaatcc taagggagtt
     2281 aattctttga tagattcaac tgattttttt aagtaaaaca atcgagtatt tacaggattg
     2341 ctcgcatctt tttcttttcc atattgctta gggcgtatca ctccgtatcc ttcattaaat
     2401 agtttatttt ctattcgttc tatattcaca ctgtaatctt caatttcatc tttttctact
     2461 ttataaataa cgcgattacc cacctcctgc aatgctataa aagttggttt ggggttttgt
     2521 tcctctgaca ataacatttt tacgatcttt tctgatgttt tcttctggac tttattactc
     2581 atataaaagt ttaaattggc actcaaaata gttaattttt ttgctgtatt agtcataaca
     2641 gagttcctcc tgttgataga tattttttat tttaggttaa attttagttc aattattgat
     2701 atttatttgg tgattctcta cttgtcgcga tagatttcat ttttatgtta attatcaaat
     2761 ctgtcccatg tttcacagtc atctttgatg tcatcttcat tacaaagtag aacatcataa
     2821 aaataatcga aagcttcttg ttcttctact accatggcaa acacctcata tataggc
//
LOCUS       DAVLUM010000124         2798 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLUM010000124 DAVLUM010000000
VERSION     DAVLUM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.124"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            332..2798
                     /locus_tag="VYN42_002013"
                     /pseudo
     CDS             332..2798
                     /locus_tag="VYN42_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808684.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
BASE COUNT          972 a          337 c          576 g          913 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagagatt ctctggagtt atggatgtcg ttccaatatg tgcacgttgg aatgttagtg
      121 cttatatggg gagaatccaa aggattctcc ctttttattt aaataagtct gtctagctat
      181 agatatatta agtttgataa aatttcttgg agattttgtt atggattata atttcaattt
      241 ggagcatcct ttctttttca ctaataatga ttatagtaca gatactagca taaagtacca
      301 agtaagtctg ccttttaatt ggcacgaagt aatgaataat gatgagtggg tttatcaata
      361 ccctattgga aaatttgttg aaagacaagg gtggaaaata cacattagtt cagagtataa
      421 cagttcacat gaattgttac aagatgtagc aaaaatttgc catgaaatgc gaattccatt
      481 taaacatctt agtacagaag acaaatttat catgcgaaac gggaaattgg ttattcgagg
      541 attttctggt aaatttatta catgttatcc aaatcaaaat gaattagagt cggttttgca
      601 aaggttagaa agtgccttaa agcaatataa tgggccatat attttaagcg ataaacgttg
      661 ggatgaagca ccaatatatc tgaggtatgg tgtgtttagg ccgtcaaggg atgatgaaaa
      721 gaaggttgct attgatgaat taattgttgg cgatgaagtt gttaaagatg aacgtttacc
      781 agtatttaaa attccaaaag gtatagtgcc ccctgacttt ttgaataaat ggcttgacaa
      841 gaaagataaa aaacagggag actttccctt tattatagat aatgcaatta gattttcaaa
      901 cagtggtggg atatataatg ctaggctaaa agaagatggg aaaaaaataa ttttaaaaga
      961 ggctagaccg tatacaggtc taggatttga tggtacttat tcttcagaga aattagcttc
     1021 ggagtgcaaa gcactaaaaa ttctaaatga atggagtgag acgcctaaaa tatactggca
     1081 cggtaagatc tgggagcaca ccttcttagg aattgaacat atgaagggcg ttccactaaa
     1141 tagatgggtt accaataatt ttcctttata tgaagttgtt gataagacca aagattatct
     1201 attgagagtt tcaaagatag tagaaaaact catcgattta acgaataagt ttcattctga
     1261 aaatgtatat catcaagatt tacatttagg aaatatcttg gttaaggatg aagatgagat
     1321 tagtataata gactgggaac aggctgtctt ttcaaatgat gaaaaagttg tacataaagt
     1381 tgcagcccct ggttttagag catggcgaga aacacttccc agtgagatag attggtatgg
     1441 tattagacaa atagctcatt atttatacat gccactagta actacatcgg atttgacata
     1501 caactatgta agtcaaacca ggatagaagg aaaaaaacta tttgagtctt tgggttatac
     1561 aagagaacat atagattatg tagaaagttt attgtcatat ctagattcta aatgtccaca
     1621 gattgagaat atttccagga aaaaagtttt aaaacccatg catgagatta gaactatcga
     1681 gagtgagcaa gatatacaag attttattat aaaattattg agagggttta cgctaactta
     1741 tggacagtgg cgtaaagaat ttcaatcaag attcttccca gttcattatt atggtctgaa
     1801 ttttaatcaa ggaattgcgt tttcagattt agctatcctt tggagttatc aacaactagc
     1861 taagaaagta aaaaatttca agtttgatga ctattatgag attcgaacac aggttattaa
     1921 tgaggcagta aataatttta agaaatcgtc cctttctggt cttttgatgg taaaattggt
     1981 acaatctggc tcatttatga atttggggag atagatcggg cagttgaact ttttacaact
     2041 cattttatag agatatttga gaattcacaa aataaaaatt tatatagtgg gcaggctgga
     2101 attttactgg ttggactgta ttttcttagt aaaggggaaa ttgataataa actaggagaa
     2161 gaaatactaa ttaggcttag agaatatact ttaaattata tagaaaatcc agaaactttt
     2221 tgtaaagttg gcgctagtga tgttcagagt aatgatcctt atgagaattt tggtggatta
     2281 ctatatggtc acgcaggggt agcttggctc ttcggtgaag cttataaatt aactggtgaa
     2341 agtatctata aaaatggtct agaattggct gtagataaag aattagttgc ttataaagta
     2401 gatagtaata attcattgca gtacagccaa ggtagattac taccatatct agcaactgga
     2461 agtgctggcc tgcttttact tattaataga aataaagaaa tcttgtcaag caaatactta
     2521 aaatatttaa cttctttaga gagggcaact gatgtagttt tttgtgtatt accaggttta
     2581 tttaacggat tttgtggtct tgaagttgct aataatatat atagtgatat cgatgataac
     2641 ttttcaggac aaaagaaatt aattgaacaa ctttatagat atttgtgtgt aattgaagaa
     2701 ggatttgtta ttgcgggaga taatggttta aagataacaa cagatattgc ttcgggattt
     2761 gcgggtgttg caattggatt ggtatcaata atggataa
//
LOCUS       DAVLUM010000125         2752 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLUM010000125 DAVLUM010000000
VERSION     DAVLUM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.125"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..852
                     /locus_tag="VYN42_002014"
     CDS             <1..852
                     /locus_tag="VYN42_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1463029.1"
                     /translation="ASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            863..1447
                     /locus_tag="VYN42_002015"
     CDS             863..1447
                     /locus_tag="VYN42_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1463030.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     YMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            1447..2142
                     /locus_tag="VYN42_002016"
     CDS             1447..2142
                     /locus_tag="VYN42_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1463031.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KKPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            2130..>2752
                     /locus_tag="VYN42_002017"
     CDS             2130..>2752
                     /locus_tag="VYN42_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1463032.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDR"
BASE COUNT          988 a          357 c          533 g          874 t
ORIGIN      
        1 gcatctaaag agggcttgat ggaaatattt tatttatcgc ccaaaataga aagattaaaa
       61 gaaattcaaa atcaagattt acaagaaggc gatgactata gcttaaaaaa atttgatatt
      121 gatctaaaag atgttgagtt tgcctacaat aaagacgcaa aagttttaaa tggtgtaagt
      181 tttaaagcta agcagggaga ggtcactgct ttggtaggtg caagtggctg cggtaaaaca
      241 actatcttga aacttatatc aagactttat gattatgaca agggacaaat cttaatcgat
      301 ggcaaagata taaaagaaat atcaacagaa tctctttttg ataaggtctc tatagttttc
      361 caagatgtgg ttctctttaa tcaaagcgtt atggaaaata ttagaatcgg aaagcaagat
      421 gcaagtgacg aagaggttaa aagagcagca aaacttgcaa attgcacaga ttttatagaa
      481 aaaatggata aaggtttcga tacagttatt ggtgagaacg gagctgagct atcaggagga
      541 gaaagacaaa gattatcaat agccagagcc ttcttaaaag atgcgccgat attgatctta
      601 gatgagataa cagcaagcct tgatgttaac aacgagaaaa agattcaaga gtctttaaat
      661 aatttagtta aagataaaac tgttgtaatc atttcacata gaatgaaatc catagaaaat
      721 gcagacaaga tagtagttct tcaaaacgga agagtagaaa gcgaaggtaa gcatgaagag
      781 cttttacaaa aatcaaaaat ttacaaaaat ttaatagaaa agacaaaaat ggcagaagaa
      841 tttatttatt aggaggacta caatggataa taaaaaatta aaagtaaaag atttagtaag
      901 catcggtgtt tttggcgtaa tttattttgc cttcatgttt ggagttggta tgatgggctt
      961 gattccaata ttgttcttaa tatacccgac agtattagcc atagttgcag gaactgttgt
     1021 tatgttattt atggctaagg ttcaaaagcc atgggcacta tttatatttg gtatgatatc
     1081 accacttgtg atgtttgcag ctggtcatac ctacgtagtt gtggttttat cacttatagt
     1141 aatgataata gcagaattaa ttagaaagat tggtaattat aattcattta aatacaatat
     1201 gctttcttat gcaatcttca gcacatggat atgtagctct ttaatgcaaa tgcttttagc
     1261 aaaagaaaaa tatatggagt ggtctttgat gacgatggga aaagattatg ttgatgtatt
     1321 agaaaagtta ataacttatc cttacatggc tttagtagcc ttaggtgctt tcttaggagg
     1381 aattcttgga gcatatatag gcaaggctct attgaaaaaa cactttgaaa aagcaggcat
     1441 tgtataatgc ctactttttc ttcaaatgct ccctttaatc ccaatccgat ctctaagata
     1501 ttagtcgtat ttatcacagg cttaactgtt atgcatagca taaacatccg ttttgagctg
     1561 gcaattgttt gtcttattgg tattttgctt tatttgaatg gatacaaaaa aacacttttc
     1621 aaatggatta tattgtgtgg gatactttac tccttgccta attttatggt gttatctgaa
     1681 ttaaacccta tagttaagat gtttttgagt atacctattg ttattagaat gtttatttta
     1741 ccatttatgg cagcaagctt tatgataaag acctcggatg taggcgcaat aatttcatcg
     1801 atggataagc ttaagatttc aaagaatgta tccataccta ttgcggttat gtttagattc
     1861 ttcccatctt ttaaggagga gaagaaaaac atcaaaatag ctatgagagt aagagggata
     1921 aattttaaaa aaccagtcaa atatcttgaa tatgtttctg tgccactact cattatatca
     1981 tctaatatat cagatgacat tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt
     2041 gccaagacca gatacattcg cgtaaagata cagctaattg attttgttta tgttttagcg
     2101 gttgctggac ttattgtggg aggcttaata tggttgaaat aaaaaattta agtcttgatt
     2161 atggtgaaga gcatatatta gatgatatat cactatccat agccgaggga gagtgcgtgc
     2221 tatttacagg aaaaagtgga aatggtaagt catctttaat aaattcaatc aatggactag
     2281 ctgtaaggta tgacaacgca aagacaaagg gcgaaataat tattgatggt aagaatataa
     2341 aaaatttgga actttatcaa atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga
     2401 catatttttt taatgtcaat acgacattag aattattatt ttatttggaa aatatcggtc
     2461 ttgcaagaga agagatggac aggcgtttga aggatatgct tgagatattc ccgataaaaa
     2521 atcttttgaa cagaaatata tttaatctat ccggcggtga aaaacaaatt ctttgcattg
     2581 cagcttctta tatagcaggt acaaagatta tagttatgga tgagccttca tcgaatttag
     2641 atattaaaag cataagtgtt ttggcaaaga tgctaaagat attaaaagag aaaggcataa
     2701 gcataattgt tgcagagcat agaatttatt atttgatgga catagttgac cg
//
LOCUS       DAVLUM010000126         2534 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLUM010000126 DAVLUM010000000
VERSION     DAVLUM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2534
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.126"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            21..1367
                     /gene="gdhA"
                     /locus_tag="VYN42_002018"
     CDS             21..1367
                     /gene="gdhA"
                     /locus_tag="VYN42_002018"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1463033.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2045..2491)
                     /locus_tag="VYN42_002019"
     CDS             complement(2045..2491)
                     /locus_tag="VYN42_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1463034.1"
                     /translation="MNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTII
                     SEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQII
                     VAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT          788 a          496 c          447 g          803 t
ORIGIN      
        1 gacaataaaa ggagaacgat atgacatctg ctaaagaata tatccaaagc gtgttcgaaa
       61 ctgtaaaaac tcgtaacggg cacgaggctg aattcctcca agctgttgaa gaatttttca
      121 acactttgga acctgtattt gaaaaacacc ctgagtatat cgaagaaaat atcttggcac
      181 gtattactga gcctgagcgc gtggtttctt tccgtgttcc ttgggttgac cgtgatggaa
      241 aaattcaagt aaaccgtggt taccgtgttc aattcaactc agctgttgga ccatacaaag
      301 gtggacttcg tttccaccca actgtaaacc aagggatctt gaaattcctc ggatttgaac
      361 aaatctttaa aaatgtctta actggacttc ctatcggtgg aggtaaaggt ggatcagact
      421 tcgatcctaa aggtaaaaca gatgctgaag tgatgcgctt ctgccaaagc ttcatgactg
      481 aattgcaaaa acacatcgga ccatcacttg acgtacctgc tggtgatatc ggtgttggtg
      541 gacgtgagat tggttacctt tacggtcaat acaaacgtct taaccaattt gatgctggtg
      601 tcttgactgg taaacctctt ggatttggtg gtagcttgat tcgtccagaa gcaactggtt
      661 acggtttggt ttactatact gaagaaatgc tcaaagctaa cggtaacagc tttgctggta
      721 agaaagtcgt tatttcaggt tctggtaacg ttgctcaata tgctcttcaa aaagcaactg
      781 aactcggtgc aactgttatt tctgtttctg actcaaatgg ttatgtcatc gatgaaaatg
      841 gtatcgactt cgatcttttg gttgatgtta aagaaaaacg tcgtgctcgt ttgactgagt
      901 atgcagctga aaaagcaact gcaacctacc acgaaggtac tgtatggact tacgctggaa
      961 actatgacat tgctcttcca tgtgccactc aaaacgaaat caacggtgaa gcagctaaac
     1021 gtttggttgc tcaaggcgtt atctgtgtat ctgaaggtgc caacatgccg agcgaccttg
     1081 atgccatcaa agtttacaaa gaaaatggta tcttatacgg acctgcaaaa gctgccaacg
     1141 ctggtggtgt agccgtttca gcccttgaaa tgagccaaaa cagccttcgc ctctcatgga
     1201 ctcgtgaaga agttgatgac cgtctcaaag acatcatgac aaacatcttc aacacagcta
     1261 aaacaacttc agaaacatac ggtcttgata aagactacct tgcaggagct aacattgctg
     1321 cctttgaaaa tgtagcaaac gctatgattg cccaaggtat tgtttaagat ttatttgctt
     1381 aatcctcaat cactacgatt ggggattttt agttgagtta gacagttggg aaattctaat
     1441 taaataaaat aaaaactgaa caaattaatt gcggaattca aaccaatttc taacatattt
     1501 ctagaaatta atttgacttt tctaatcgat ttgttcatat cttatttcaa tttactatac
     1561 ttacttaacc ctttttatac tcaatgaaaa tcaaagagca aactaggaag cgagtcgcag
     1621 gctgtacttg agtacggcaa ggcaaagctg acgtggtttg aagagatttt caaagagtat
     1681 taaacaaaaa gaaaaaacgc tactcctaag aatagcgatt taatcatgtt tttaagctac
     1741 tactgtagtt gctctattat ttaagtgtta tgaataactt caatatcttt aaagcttttt
     1801 gttagattta taatttcaac tatagccatc tctactcctt agtgtacagc aaaaaattat
     1861 gcttaattct tattgttttt gtaaacaatc agcgaaccca atactattcc attcaacaat
     1921 cctaaagaaa taccatattc aactggaaaa tctaaaaaat tgcaaacact attccaatca
     1981 tcacccctag tgaggctgtt gttaaaatta catattcatt ttctttcttc attttcttta
     2041 cacctcattt cctttttgta tataagctgt agtactctcc accaagatcc attaagtact
     2101 tatgatttcc tgactcaaca atcttaccac ctttcattac aacaataata tccgcatcct
     2161 taatcgttga caatctatga gctacaatta tttgagtaca gccctgactt tttatatact
     2221 ttgttattct ttcctcatta atagtgtcta aagcactagt tgcttcatct aaaattacaa
     2281 tactaggatt atttattaat gcacgtgcca gtgctatccg ttgtctttga ccacctgaaa
     2341 tatttgaacc catctctgag atgatagtat taaatttcat cggcatagcc atgatttcat
     2401 catagatttg aactgcttta caaacttcct ctatcttttg tgaagtaact tcgtgcttta
     2461 aagttatgtt atcaagaata cttctgttca ataaaaacga atcctgtgga actactccta
     2521 aattttgact taat
//
LOCUS       DAVLUM010000127         2391 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLUM010000127 DAVLUM010000000
VERSION     DAVLUM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2391
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.127"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            77..1600
                     /locus_tag="VYN42_002020"
     CDS             77..1600
                     /locus_tag="VYN42_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016648332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1463035.1"
                     /translation="MFSHILGFRLETNLRKRGIDGLEKASFRFFDLNPSGQIRKIIDD
                     NAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGIILLALTIIGGLILGAMMGE
                     QEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFKSFYKAIKDYSKYAYDYSLS
                     CKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLELIMILFLSGVLFVSFMRMM
                     WYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNYNIEFENVSFAYNDKAVIEN
                     LSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSIKIGGIAISEYSDEALIKAI
                     SFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGCDLILDKFPERENTIIGSKG
                     VYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEFELQKAFKNLMKDKTVIMIA
                     HRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSLQEMFNSANEWRVSNERVL"
     gene            1584..>2391
                     /locus_tag="VYN42_002021"
     CDS             1584..>2391
                     /locus_tag="VYN42_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1463036.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKE"
BASE COUNT          850 a          323 c          446 g          772 t
ORIGIN      
        1 atccggtgca gagagcatag cattaaaatc tgttattaca ctaacaagtg gagcgatatt
       61 ttattttgtc tcaggaatgt tttcacatat cttgggattc aggcttgaaa caaatttaag
      121 aaaaagggga atcgatggtc tggaaaaagc aagttttagg ttctttgact taaatccatc
      181 tggtcaaata agaaagatta tagatgacaa tgctgcacaa actcatcagg tggtagcaca
      241 catgattccc gatagttctc aggcaataat cacacccgta cttgtacttg cacttggctt
      301 tatagtaagt ataagagttg gcataatttt gcttgctctt actataattg gtggcttaat
      361 tttaggggca atgatgggcg agcaagaatt tatgaagata taccaagaat ccctatctaa
      421 actaagtgct gaaactgttg agtacgtgag aggaatgcaa gttgtaaaaa tatttaaagc
      481 aaatgtagag tcttttaaaa gcttttataa ggcgataaaa gattactcaa agtatgctta
      541 tgattattcc ctatcttgta aaaggcctta tgttttgtat caatggttat tttttggact
      601 gattgcaatt ttaattattc ctatagttta ttttatgact agcttagcta gcgcaaaggt
      661 gattttactt gagcttatca tgattttatt tttatcagga gttctctttg tttcattcat
      721 gagaatgatg tggtactcca tgtatatttc tcaaggaaat tatgcagtag atactttaga
      781 ggcgctttac gaagatatgc aaaaagacaa attagtgcat ggtaatatca ataattttaa
      841 aaactataat atagaatttg agaatgttag ctttgcttat aatgataaag ctgtcattga
      901 aaatttatcc tttaatttag aagaaggaaa gtcctacgca cttgtcggtt catctggatc
      961 aggcaaatca acagtagcaa aacttatatc aggtttttat aatgttaata aaggaagcat
     1021 aaagataggc gggatagcaa taagtgaata ttctgacgaa gccttaatta aagccatttc
     1081 ctttgttttt caagattcaa aattattcaa gaagagcatt tatgataatg tagctttagc
     1141 taataaagat gcgacgaaag atgacgttat gagagcctta aaattagcag gatgcgattt
     1201 aatattagac aaattcccag aaagagaaaa tacaatcata ggctcaaaag gtgtttattt
     1261 atccggtgga gaaaaacaaa gaattgcaat tgctagagca attttaaagg attccaaaat
     1321 tattattatg gatgaagcat cagcatctat tgacccagat aacgagtttg aattgcaaaa
     1381 agcttttaaa aatcttatga aggataaaac agttatcatg attgcacaca ggctatctac
     1441 aattaaagac cttgatgaaa ttattgtcat ggatagtgga aaaattatag aaagagggtc
     1501 tgacaaagaa ttaatgtcaa aagatacaag gtataagagc ctgcaagaga tgtttaacag
     1561 tgcgaatgaa tggagggttt caaatgaaag agttttataa aaaaagattt gctcttacag
     1621 atggaggagc aagaaattta agtaaagcaa cactggcttc atttttcgtt tattgtataa
     1681 acatgcttcc tgccatatta cttatgattt ttgctcagga agttttggaa aatatgggca
     1741 aaagcaatgg cttttatata gtattctcag ttttgacttt gatagcaatg tatattttgc
     1801 tttctatcga atacgataaa ttatataaca caacctatca agaaagtgca gatttaagaa
     1861 taaggacagc ggagaattta tcaaaattac ctctatctta cttttctaaa catgacattt
     1921 ccgacatttc acaaacaatc atggctgata ttgaaggcat agagcatgca atgagccact
     1981 caataccaaa ggtgggcggc atggtactgt ttttcccatt aatatctgta atgatgctag
     2041 cgggcaatgt caagatgggt ttagctgtaa ttattccatc tattttaagc tttatattta
     2101 tacctttatc taaaaaatat caggttaatg gacagaatag atattatgat gtcttaagaa
     2161 aaaactcaga aagctttcaa gaaaatatcg aaatgcaaat ggagattaaa gcatataatt
     2221 tatcgaagga tattaaagat gacttatata aaaaaatgga agatagtgag agagtacact
     2281 taaaagcgga agtaactaca attttaactt tgtctatatc ttcaatattt agctttatat
     2341 ctcttgctgt tgtgatattt gtcggcgtaa atctaattat taataaagag a
//
LOCUS       DAVLUM010000128         2360 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLUM010000128 DAVLUM010000000
VERSION     DAVLUM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.128"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..76
                     /locus_tag="VYN42_002022"
     CDS             <1..76
                     /locus_tag="VYN42_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV1463037.1"
                     /translation="LKKLLSDKEKLSPKKWNEEKILLM"
     gene            402..575
                     /locus_tag="VYN42_002023"
     CDS             402..575
                     /locus_tag="VYN42_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463038.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            875..1288
                     /locus_tag="VYN42_002024"
     CDS             875..1288
                     /locus_tag="VYN42_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV1463039.1"
                     /translation="MNETLEKANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDL
                     KKELNKLGVSFSVMKNKESKNYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIK
                     KYKDLSKNKDKTKEKEKRKVKEKVKPNKKDMTREI"
     gene            1415..2119
                     /locus_tag="VYN42_002025"
     CDS             1415..2119
                     /locus_tag="VYN42_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1463040.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEIVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKKSTPIFYGEF
                     KNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLR
                     QKGLNKKMNYDVGESL"
BASE COUNT         1179 a          306 c          380 g          495 t
ORIGIN      
        1 attaaaaaaa ctcctatcag ataaggaaaa actaagtcct aaaaagtgga atgaagaaaa
       61 aattctttta atgtaaaatc ttgaagaaat aaataaagaa aaagacaaga taaaagatga
      121 ataccaggaa attaatcata taaaatattc agtagatttt gtaaacaaag aacttggtat
      181 agatttatcc atagaaatag ataagctaat aaaacaggga gaaaaaccaa gtgtaatagc
      241 acagattaaa aagttccaag accaagtcaa taaagataat gaatacagag aaatgatgaa
      301 aaacaagaaa atggatcaag aaagataaga cctggtaaaa atatcttatc caagctataa
      361 tatgaccaaa caactaaagt cagatctagg aggtaataga gatgaataaa aggcaagagc
      421 taatagatga actcataaaa gcaaatgaag atggaacata caaaacctat aaaagcacag
      481 aagaaataaa agcaatgaac aatgaagaaa tacagattat atattccaac atgaaaaact
      541 atctatcaga caaaagaaca cacataaact attaaaggtg gaaaggtagt gtaagctatt
      601 tttaaaagta taaaaggtac aaagacctaa gaaatatata aaaacatcaa aataaagtat
      661 tccaccacca agaacaataa aataaaaaca agcaaaggga agtatagaaa aattaaaacc
      721 tatacttccc ttttttaatt caaacaaagg agagaaaagc atgataaacg aagaaataag
      781 caaggaagca ggtcaagcag cacaaaccat aatatcatac acaataaagg caacaaaaga
      841 atcaatcaat ttataaaaag aaataagaaa aaagatgaat gaaactttag aaaaagcaaa
      901 tggaaactta aaaagtctta tgggcgatga aatgaaaata aaagacctct acaagaaagg
      961 acaactagaa aatataagca tagatcaaat cgacctcaaa gacttaaaaa aagaactaaa
     1021 caaacttgga gtaagtttct cagtaatgaa aaacaaagaa agcaaaaact atgaaatatt
     1081 cttccaagcc aaagacataa aagtaatgga atatgccttt aagcaagtca tagccaagga
     1141 aaataaaaaa gaaaaagaaa gtatcctaaa acaaataaag aaatacaaag acctatccaa
     1201 aaacaaagat aagacaaaag aaaaagaaaa aaggaaagta aaagaaaaag taaaaccaaa
     1261 caaaaaagat atgaccagag aaatctaaag ggagtaacga aaagttacac ccttaaataa
     1321 ccataataac aagacttccg aaaaacagaa gttcagaatt ccgaaaatcg gaaatcaaga
     1381 atttcgatta tcgaaaatca agaaaggagc agatatggca acaaacaaaa gatactattg
     1441 gataaaatta aaagaagaat ttttcacaga caaaaggata aaaaggttaa ggagaatatc
     1501 tggaggagat acctatacga taatctacct aaaacttcta ctactaagcc taaaagatga
     1561 gggcaaactc tattatgacg gagtagaaag tgattttata aaagagttag cactaaccat
     1621 agatgaaaca gacgatgatg taatggtaac agtaaattat ttaatcaatc aaggcttatt
     1681 agaaattgta acagaaaatg atgaatacta cctaactgaa ataccaaact taatcggatc
     1741 agaaacagcc tgggcagaga aaaaaagaag atacagacaa aataaacaga ggacattgtc
     1801 cttaatgagt ccaacccatg tccgacaaga gatagagata gagaaagata tagagataga
     1861 taaaaagtcc acccccattt tttatggaga atttaaaaat gtaaggttaa gcaaagaaga
     1921 atataaaaat ctaaaagaaa aattaaactc gcacacagat ataatgataa ataaactatc
     1981 cagatacatg gaaagcagtg gtaagaccta tcaaaaccac tatgtgacaa tcttaaaatg
     2041 gtatgaagaa gataaagaca aactaagaca gaaaggttta aataaaaaaa tgaattatga
     2101 tgtaggagaa tctttataga taaaaagagg tggaaaggca ctattaaaga ctttaagtct
     2161 aaaaaggtat caaagtatgc cagagataaa aaaatataaa tatgacactt taagggcgat
     2221 tagaaaatta aagaaatgct agaagacttt tagatgacag ttaccaagaa ggtctaattt
     2281 tcactgctac ttatgcagtg aaaattagac ctttttatat aagcaaattc tatttcaaaa
     2341 ttggttacca agaaagactt
//
LOCUS       DAVLUM010000129         2220 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLUM010000129 DAVLUM010000000
VERSION     DAVLUM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.129"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..1341
                     /locus_tag="VYN42_002026"
     CDS             <1..1341
                     /locus_tag="VYN42_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463041.1"
                     /translation="YYNFFDSEKGKFPYTDEMDIFSFHGHSREDKLFIYNGYVCCTNN
                     DNNVMETRNINDIPHWAKNPEYYEGKKDIVDIKEIKCKIAFLNSCSGIHLKKSLYRKE
                     YWISEGFRVSYPAVVIGSTIIKDGSSIENIFFIELIKAGYSVGESVNVLNKMSKALKY
                     DTGSFCILGAPEFRLTTPNSRFENTLHEIQQFTENLIVLKNRLKKYLEIFHKQKRIDI
                     YGIKDKRIQNIQMNVGNQLQSLVRKINISNIHRYNLGQLNHEMDSLESQLTDLQNRII
                     SDLSTKTRTGNYLFSEYYHELSEIDYEEFRENSCPNCNNSILLQKFTVVPENINRFVY
                     KCSRCGTSIDLPSNVFVDINLKIEINIEELEIKVFFDYQNLIKKGEFTTIDCEILEAD
                     RYSIERVVANNQDNVQGEITFKYNRQKTPMQVYYLKAYVMIDGQLLHRSIPINL"
     gene            1370..>2220
                     /locus_tag="VYN42_002027"
     CDS             1370..>2220
                     /locus_tag="VYN42_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HEV1463042.1"
                     /translation="MESKISILDRLYSWIYIKKLKKLGAIIEENVVICFGAKLFFNEE
                     CLIQKDTVIGRFVLIEANRITIGNNCLFFPRTLIYSKETFSLGTRGKISKDCIFRANK
                     INIGREFWCNEAVRIGEGGWNQKSANIKIGDYQFIGPRAQINVSDSVELMGYGGLGIE
                     TMIFTHGAGHGQSATDGFYAEQNKVIIQKNVSILTRAIILPGVIVSQGTTVAANAIVT
                     KSFPKHSLIGGVPARYIGQSNKEISVKEQKNIIVDILKEGLGTEPVIKNNSFCFEKFN
                     ENITFQY"
BASE COUNT          852 a          246 c          420 g          702 t
ORIGIN      
        1 tattataatt tctttgattc tgagaaggga aaattcccat atactgatga gatggatatt
       61 ttttcattcc atggacacag tcgagaagat aaactcttta tttataatgg atatgtatgt
      121 tgtacaaata atgataataa tgtgatggaa acgagaaata tcaatgatat tcctcattgg
      181 gctaaaaatc cagaatacta tgagggaaaa aaggacatag tagatattaa agaaataaaa
      241 tgtaaaattg cctttttaaa ttcttgtagt ggtattcact taaaaaaaag tctatatcga
      301 aaggaatatt ggatttctga aggctttcgt gttagctatc cagctgtagt aattgggagt
      361 actattatta aagatggtag tagtattgaa aatatattct ttatagaatt aataaaagct
      421 ggatatagtg tgggggaatc agttaatgtt ttgaacaaaa tgtcaaaagc cttaaagtat
      481 gatactggtt cgttttgtat tttaggtgct cctgaattta ggctgacaac tccaaatagt
      541 aggtttgaga atacattgca tgaaatccaa caattcactg aaaatcttat tgttctgaaa
      601 aatcgtttaa aaaaatattt ggaaattttt cataaacaaa agagaataga tatttatggt
      661 ataaaagata aacgaattca aaatatacaa atgaatgtag gcaatcagct acaatcgctt
      721 gtgagaaaaa tcaatatttc aaatatacat agatataact taggtcaatt aaatcatgaa
      781 atggatagtc tagaaagtca attaacggat ttacagaata gaataatttc cgatttgagt
      841 acgaaaacta gaacaggaaa ttatttattt tcagagtatt atcatgaact ttcagaaata
      901 gattatgaag agtttcgaga aaactcttgt cccaattgta ataattccat tctgctacag
      961 aaattcacag tagtcccaga aaatataaat aggtttgtgt ataaatgttc aagatgtggt
     1021 acatcaattg atttacctag taatgttttt gtagatataa atttaaaaat tgaaattaat
     1081 attgaagaat tagagataaa ggtattcttt gattatcaaa acctcattaa gaaaggggaa
     1141 tttacaacaa tagattgtga aatattagag gccgatagat attcaattga aagagtagta
     1201 gctaataatc aagataatgt gcagggggag attactttta aatataatcg ccaaaagaca
     1261 ccgatgcaag tatattattt gaaagcatat gtaatgatcg atggtcagtt actacatagg
     1321 agtattccta taaatttgta agttagttaa gaattgttgg tgattagaca tggaatcaaa
     1381 aatttcaatt ttagatagac tatattcatg gatttatatt aagaaattaa aaaaactagg
     1441 tgcaattata gaagagaatg ttgtgatttg ctttggtgca aagctttttt tcaatgaaga
     1501 atgcttaatt cagaaggata cggtcatcgg tagatttgta ctaatagaag caaataggat
     1561 aacaattggg aataattgct tatttttccc acgaacttta atttattcca aggaaacatt
     1621 tagtttggga acacgaggaa aaattagtaa agattgtata tttagggcga ataaaataaa
     1681 tattggaaga gaattttggt gcaatgaggc agtaagaatt ggagaaggcg gttggaatca
     1741 aaaaagtgca aatattaaaa ttggtgatta tcaattcata ggaccacgag ctcaaattaa
     1801 tgtaagtgat tctgtggaac tcatgggata tggtggtcta ggaatcgaga cgatgatctt
     1861 tacgcatggt gcgggacatg gccaatcagc aactgatgga ttttatgctg aacaaaataa
     1921 agttattatt caaaaaaatg tctcaatttt aacaagagct attattctac caggtgttat
     1981 agtcagtcaa ggcaccactg tagcggcaaa tgctatcgta accaagagtt ttccaaagca
     2041 ctcgttaata ggaggagtac cggctaggta tattggtcag agtaataaag aaatttctgt
     2101 gaaagagcaa aaaaatatta ttgttgacat attaaaagaa ggattaggaa cagaaccagt
     2161 gataaaaaac aatagctttt gttttgagaa atttaatgaa aatattactt ttcaatatga
//
LOCUS       DAVLUM010000130         2087 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLUM010000130 DAVLUM010000000
VERSION     DAVLUM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2087
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.130"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            116..856
                     /locus_tag="VYN42_002028"
     CDS             116..856
                     /locus_tag="VYN42_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1463043.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            859..>2087
                     /locus_tag="VYN42_002029"
     CDS             859..>2087
                     /locus_tag="VYN42_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463044.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILP"
BASE COUNT          682 a          268 c          379 g          758 t
ORIGIN      
        1 gtatttcatt tattgaagtt tcacatcatt atgacttaaa tgacaagaga tacactgata
       61 tatataaatt ggaaaatgga acacttttca aaattaagtg attggaggca agaatatgga
      121 taaagattat atattaaaag tgaaagggct gtatcatcaa tttttactag gaaataataa
      181 aacgttgcaa gtgctgaaaa atgtttctct ttctgcttcg agaggagaat ttataagtat
      241 tctaggaatt agtggttctg gaaagtcaac tttattaaaa tgtatttcta gtttgcttga
      301 accaacaagt ggggaagtaa ttttaaatgg aatcaacccc tataaaatca gaaatgcaaa
      361 attgtcaagt ataagacgta acgaagtatc ttttatattt caagcataca atttaatacc
      421 ttccctgccg gtaatagaaa atatagcact tcctttgcga ttatcacaaa aaaaattaac
      481 tattaaaaat gtagaaaact tactcaaaag aatgaagttt aatgctggct taaacgattt
      541 tgttggaact ctgtctggtg gagaacaaca gaaggttgct atagctagag cggttattgc
      601 tgatagtgat ataatatttg ctgatgagcc aactggggct ttagacagcg tttctcgtga
      661 agtaattttt gaattattga gagagttagt aggggcgggt aagtgtgtaa ttatggtaac
      721 gcacgatata gaattggcct cgaaaactga tcgtgcatta atattgaaag atggaaaaat
      781 tttcaaagaa cttcatagac ctagcgggga agagttgtat aaaatcttag aggtacaatc
      841 aactacggag gaatagagat gctcagatta gtttactatc aatttttaca taataagaaa
      901 caatggttag gcgtttcacc agtaattttt gtttcgagtt tagttatggg attggctgtt
      961 aatggggtaa ttaatgttga gaataattcg caagtatttg tcggacttcc agatcctaaa
     1021 ccaattttta tgtttccgat agtattcgga ggagtaacat tattctttgt gctctctaac
     1081 ataataaata tgttggttga aatttttaga gatgattacg aacttctgga ggtgttggga
     1141 gcaagtctcc ttcaactatc atttcttgtg gggggacaga tttttatcat ttcctcgatt
     1201 attagtttta ttgcatatct atgctctata tttgttacgt caaattatta ttatttttta
     1261 caatactttt tcggggaaaa tatattacct gatatccaat ttcaaacgag tgctgttgga
     1321 tgtatcatta cagtagtgtt gatttcattt ttagcctttc taagtggttg cttttatacg
     1381 ttcaagaaga ttagaaatag gaagagttct aaaataaggc atgttctttc aatagtaaaa
     1441 agaatactgc tattggctgg ttttagtgtt atctggttgc tttctttgca acaaattttc
     1501 caagatagca caattttagc gaaggcccag ataatattca atattgtaat cttagatatt
     1561 gtgattattt atcaattatc tccttttata cagtcatgtt ttatcaaact actttctata
     1621 attatattta gaaataattt tatgttcatt gtttcgaagt ggaatttact atatcgtaag
     1681 ccttatataa aatctatcag tgctgcaatt acaggagcta tattactaat ttctagtttt
     1741 caaatgattt ctcagaatat actatctcaa tttcaagatg acagtgattt agagctaaaa
     1801 gtggcattta ttgtctatgt aggagcacca attttgatag tacttgcaaa tattatttca
     1861 attgcatttt tgtcatcgca tcaagaaagg attgagattc agcaatttga aattttagga
     1921 acttctaatt accagatggt taagattaaa gttggtgagg ctatattttt gacatttgtt
     1981 acttcattaa ttgcattttt acttaacatt aaaattatgg ctttaatata ctactcttta
     2041 gaggatattt taatagatga tatgaatctt ttggggttaa tacttcc
//
LOCUS       DAVLUM010000131         1908 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLUM010000131 DAVLUM010000000
VERSION     DAVLUM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.131"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            94..1725
                     /locus_tag="VYN42_002030"
     CDS             94..1725
                     /locus_tag="VYN42_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1463045.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNTTNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIGLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT          548 a          403 c          374 g          583 t
ORIGIN      
        1 ttacaaactt gacattaaca cttgttagat ttacttttat cctttaaaat agaataggag
       61 atattccgcg attatttttc ggaggaaaaa gaaatgtcca ttaattggca ggaaatttta
      121 tttcactttt taggtggtct ggggctattc ttatatagca tcaagaccat gggagacggt
      181 ttacaacaag ctgctggaga tcgccttcgt ttttacattg acaaatatac tagtaatcct
      241 ttctttggag ttctggttgg tattgggatg actgctctaa ttcagtctag ttctggtgta
      301 acagttatca cagtcggcct ggtcagtgcc ggtctcttaa ccttacgtca ggctatcggg
      361 attgtcatgg gtgctaatat tgggacaact gtcacatcct ttctcatcgg ttttaaatta
      421 ggtaactatg ccctacctat gctctttatc ggtgccgtct gtctcttttt tacaaaaaat
      481 cggacagtca ataatatcgg acgcatcctc tttggtatcg gtggtatctt ttttgccctc
      541 aatctcatga gcggcgcaat ggctccactc aaggatttac aggtctttaa ggactatatg
      601 attgagctaa gtaagaatcc tgttttgggt gtctttgtcg gtactggctt gaccttgcta
      661 attcaagctt cttcggctac cattgggatt ttacaaaacc tctacgccgg caatctaatt
      721 gacctacagg gagctttgcc agttctattt ggtgacaata tcgggacaac cattacagcc
      781 atcattgcct ctttaggggc taatattgca gctaaacggg tagcaggagc tcatgttgcc
      841 ttcaacgtta tcggaacagt cgtctgcgtt atttttctag ttccttttac tgtcctgatt
      901 cattggtttg aagctacgct aaatctagca ccggaaatga ccatcgcctt tgctcacgga
      961 acctttaata ctaccaacac cattgtccaa tttccattta tcggagctct ggcttacttt
     1021 gtaaccaaga ttattcctgg agaggacgag gttgtcaaat acgaaccctt atatcttgat
     1081 gaacatttca tcaaacaggc cccatctatc gctctaggaa atgctaagaa agagctcttg
     1141 cacttaggaa actacgctgc taaagccttt gacctttcct ataagtacat cattggcttg
     1201 gatgaaaaag ttgctgaaaa agggcataaa accgaagaag caattaacac catcgatgag
     1261 caattaacac gttatctcat tgccctttca agcgaagctc tcagccaaaa agaaagtgaa
     1321 gtgcttacca atatccttga ttcctcccgt gatttggaac ggattggaga ccacacggag
     1381 gctctactca atctgactga ctatcttcaa cggaaaaatg ttgaattttc tgatgccgcc
     1441 ttgaaagaat tagaggaagt ttaccgccaa actagtgact ttatcaaaga tgctctggat
     1501 agtgtggaaa acaatgatat tgaaaaagca cgcagtcttg tagaacgtca tgaagcaatc
     1561 aataagatag aacgtgttct cagaaaaacc cacatcaaac gcctcaacaa aggcgaatgt
     1621 tcaacacaag ctggggtcaa ctttatcgac atcatctcac actacactcg tgtatcagac
     1681 cacgctatga accttgctga aaaggttttt gcagaacaaa tctaagaacc aagaagctat
     1741 ccatcataat tggatggctt cttacttttt cctaagcaag actaggctga atgaaactga
     1801 aagagtattc tgcagatata tagtatattg aaactagaat agtacacctc tatttctaaa
     1861 acattcttag aaatcgattt gactgtcctg atcgatttgt cctgttat
//
LOCUS       DAVLUM010000132         1905 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLUM010000132 DAVLUM010000000
VERSION     DAVLUM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.132"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(325..1218)
                     /locus_tag="VYN42_002031"
     CDS             complement(325..1218)
                     /locus_tag="VYN42_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1463046.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
BASE COUNT          642 a          381 c          209 g          673 t
ORIGIN      
        1 acttttatac gattactacc tctttttagt ttacacttcc tacatcataa ataaacatac
       61 tcaaccctca caatctccaa ataactcttc tatatcattg aaaattgagt ttcatcctct
      121 atactaatgt aggacattcc tttaatccaa tataagaata ccttgttcca ttaatctcta
      181 cccgatatta tagatagaac caaattccta tacttaaaag gacaaataac gttccaacca
      241 taataaacct cctttctttt tgagaacgtt ttctttatag gtttagtata gcaaaaacat
      301 gaaaaaaaca acatgactta gaagtcaggt tgttgggaaa tctatctgtt tttctgctaa
      361 aattctctga actaatacct gatcgtctag caattctgct agagaaatcg ccttttcata
      421 gaaactttct gcctctaaaa tattcttgtc tacaaataaa gcatattttg cctttagcaa
      481 aaatagatga ggtcggtaaa aaacatgtct tgttttagca ataattttct caaatgtttg
      541 aatatatatc agactatcct ctgtctgaat ttggataaat aggctcagaa gaactttttc
      601 catttgaact aggctagcct tatcttcata ttctgaacat agcaatactt tttgagctaa
      661 ctcctcaaaa tgttctttat cttctaatcc catagcacaa caaaagaaat acaattcaat
      721 aatcaacaaa tcatttacag aaaaatattt cttttttaat aactgctgga aatattcttc
      781 cactaaccct aaaccgtagg tcacatctga actaccataa atatcaaaac gagcttgtgt
      841 cacatccaca attaactgct cttcctcagg caaattctca taatagtttt catatatttc
      901 ctcaagtata gcttcttttc gttcgattct tcccttatca gcgtaggttt gagaatgaat
      961 cagctcatct ttgagtttta ggaatccttt tggaatctct ataaccttaa catccacaat
     1021 attctgtaat gatactccaa gtttatccgc aatcaataat aatttaggaa gtgttgctaa
     1081 agcttgccca ttttcaatac gtgctagctg acgaatcgtc aactctgatt catcaccaca
     1141 aatatctatc tgagtttttc cacaagatcg cctaatagtt ttgattttat aaccaatttc
     1201 acgtttcaac tcatccatag taatactcct taagttgatt acaaagattt ctttttcttc
     1261 ctaattcttt tgtcaatcat atataaaacg ataagcgaaa acagcggtag aacaatataa
     1321 ctcttttcac tcattatcag ctgaaatccc agggttgcta gtatcttaaa gatgaaaata
     1381 ttcatcaaaa atagaaaaac aaatactaaa aaatatttta aaaccttctt catttctttt
     1441 cttcaacttt cctaatttct acacctattt tatcgaaaat atatataaaa ctccaaataa
     1501 acacttcgac tgcacttttt ttggcaaaaa atagacagaa caaacatcct acctactaaa
     1561 aatatgatat gaaaggaaaa tgatttttta ctgacaccct aggcaagctt gggacaaata
     1621 aatcattgat agcaacattt acgacatcct atttaaagtt ccttcaattt ctaatgtccc
     1681 cgctatttct aagccacctc tggtatgatc tattcctagt cagaatagat aacaccgttc
     1741 taaattacga ttcatagtta ctcttttttg actcgttact ataagactcc tatttacatg
     1801 cgcaaaataa ttttgattca gattcatcat ttatagtttt gattattttt taacagattt
     1861 ttctgttttc ttctccgaag actttaaaaa tttttttcta attaa
//
LOCUS       DAVLUM010000133         1892 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLUM010000133 DAVLUM010000000
VERSION     DAVLUM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.133"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(1..348)
                     /locus_tag="VYN42_002032"
                     /pseudo
     CDS             complement(1..348)
                     /locus_tag="VYN42_002032"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(386..718)
                     /locus_tag="VYN42_002033"
     CDS             complement(386..718)
                     /locus_tag="VYN42_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1463047.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(731..1504)
                     /locus_tag="VYN42_002034"
     CDS             complement(731..1504)
                     /locus_tag="VYN42_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1463048.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGIGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
BASE COUNT          645 a          343 c          198 g          706 t
ORIGIN      
        1 ttctacaaat ttgaatgtag atttttcaaa aacttttgtg tcatctttta ataatttttg
       61 taatttcatt tcaaagtagt ctgcatatat tagatgtgaa ttttcaaggc aacagaacca
      121 aaaatttaaa caagctgaca caactaaatt tctattcttg ccgatttttt cgtaataatg
      181 tgtacgctct agtatttctt ttccgaccat gtaaatataa tctatttcaa aaagatgata
      241 taaattacca atcagcgtta tctcatagga ctcccatcgt tccttctgga ataaatagtc
      301 atatactaaa tttagatcat ctctactaac tacatgatta caatctagct gatttcataa
      361 tccctgaacc ataattgtat ttattttatg agtttttccc actcttctca aaaagttttt
      421 gttgcttatt ttttattacc tccaatcctt taatattcaa actataaaaa tttggagata
      481 aattaaccaa aaaatcatca cgctccgatc ttttataatg ttctaagtga ttacaaaaat
      541 tctctatcga aacattgata tttgataata attcaaaaaa tgttgaaaga gaaatttcat
      601 tttctcccct ttcaaatcta gaaagttgag attttgatat agaatcagct gcagcatact
      661 ctaaagaata tccgtttaat tttctaaaat atcgaaaagc ttctccgtaa tttttcacac
      721 tttcattccc ttaactttct tttcgagcga taaacatacc atattcttta ggaatgatca
      781 acataccatt attaaactca ctttccaatc ttttacgtat tatttcctct tctagtgaac
      841 ctatttctga aattccttta aacgattgga tgtatttaac taggtcatct atactagtta
      901 cctgtaactc atcatcatag agtaatgtat cgacagagtt aaaataccta ctcaggtacc
      961 ttttaccatt ttgtaaagta aacgttctat tttctaaatc ttgattaacc tcatctttaa
     1021 ataaacttgc caaataattt acaactccat tttcaccaaa tgtagcacag taaaaaattc
     1081 ctccggtttt taagacccta ttcacctcag agagagcttt aggaatatca ttcacatgat
     1141 gtagaagcat attagcaata acaatatcaa aagtttcatt ctcaaaagaa atcttttgaa
     1201 tatccattat ctcataattg acattgtttc tatttccaat cactgacttc gttgatttta
     1261 ccatatcttt agaaaaatct gtaacaatca actgcttcat tttatctata gaatcactat
     1321 tacttttcca caattctcct ataccacatc ccaattctag aacctttact tcatcagtga
     1381 tttggtagtt agaaaatatc caattattaa atcccaattt attttttgaa tacttcttat
     1441 gcaattctac tcgaatatca agattatcat gacttttata ttgttcaatt actttatcaa
     1501 tcattttaaa tgacctccac tctataattt ggcattatat cacaagaata aagatagtgt
     1561 taaataagtt gtataaatgc aaaaaaggaa taaatccatt atagcagagt tacaacacat
     1621 tactagaaag agatttattc ctacgactca gtttggcatg cttaacttcc taactcaaaa
     1681 acaaagcatc gattaattta tccgttcttc ttttgaaaca gatttgaact gataattgct
     1741 cgttttaatt taagaagctc ttttgagcaa aacttcattt ttttaagagt ccaacaattt
     1801 ctgtctatcg cttttctact agcaaaaaaa cctaccttga ggcaagtttt catttatata
     1861 tctaatttcg taatagtata gtaaaatgaa at
//
LOCUS       DAVLUM010000134         1885 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLUM010000134 DAVLUM010000000
VERSION     DAVLUM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1885
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.134"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            26..823
                     /locus_tag="VYN42_002035"
                     /pseudo
     CDS             26..823
                     /locus_tag="VYN42_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(858..1704)
                     /locus_tag="VYN42_002036"
                     /pseudo
     CDS             complement(858..1704)
                     /locus_tag="VYN42_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(1812..1885)
                     /locus_tag="VYN42_002037"
     tRNA            complement(1812..1885)
                     /locus_tag="VYN42_002037"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1849..1851),aa:Asn,seq:gtt)
BASE COUNT          595 a          376 c          317 g          597 t
ORIGIN      
        1 gattttctag tataaaaaaa ttcaaactag aattcttctt agaaaaggcc gttttaagtg
       61 ctatcattgc tcaaaaatgg aggtcgctga gacttctatc gtcaagaaga atcatcaaat
      121 tccttgtatc atcaaccaaa agattgctca gaagctaatt gaaaagactt ctatgaccga
      181 cattgatcat cagttgtcta tttcaacttc aactgtcatt cgcaagatca ataattttca
      241 ctttgagcat gatttttcgc gtcttcctga gattatgtcc taggacgttg aaacagtccg
      301 gggagtgact gtttcaatcg ggagatggag atgagcttta ttgctcagga ctttgataaa
      361 ctcaatatca taactgttct tgagagcaga acacaagcca tcatccgaaa tcccatgaat
      421 acaaggctat caagcgctac tggaagctca ttcaacaaga tagtcagaaa ctgagtgata
      481 aacgatttta tcgccctact tttcgtatgc acttgactaa taaagaaatt ctagataaac
      541 ttttgagcta ttccgaagac ttgaaacacc actataatct ctatcagctc ttgcttttcc
      601 acctctgttt cagactttgt ttaaaacctt cctcaaagat aaagagaaaa tcgtcaacgc
      661 ccttcaatta ccttattcca acgccaaact ggaagccacc aataatctca tcaaacttat
      721 caagcacaat gcctttggtt ttaggaactt tgaaaacttc aaaaaagaaa ggacgaaatt
      781 tgtcctttct agatcttcgc tttcttcaac ccactacagt tgacaaagaa ccgaaaaatg
      841 tctcgcctct aatatagtca attgaaacaa gaacaagaga aaagagcctc gtaaaaggta
      901 ttgcaacttg gtaatacctt tttgaggttc tttttgatat aagcccatgt tttctcaata
      961 ggattgtact caggtgagta gggaggaaga ggtaaaagtt tatgcccaaa ctcctcgcat
     1021 aaaagttcta acttacccat tctatggaat cttgcattat ccataataat aaccgatggt
     1081 gtggttaatg ttggtaagag aaacttctga aaccaagctt caaaaaagtc gctcgtcacc
     1141 atctcttcgt aagtcattgg agcgattaac tcaccatttg ttagacctgc aaccaaagaa
     1201 atcctctgat atcttcttcc agatacttta cctcttatta actgaccttt taatgagcga
     1261 ccatattctc gataaaaata agtatcgaat cctgtttcat caatctaaac aggtgctagg
     1321 tgctttaaac tattaaaatt tttaagaaat aaggctactt tttctgggtc ttgttcatag
     1381 taggtgtggt tctttttttc gagtgtagcc catagctttg agcgcatagt ggatggtagt
     1441 tggatgacag ccaaattcag aagctatttc agtcaaataa gcgtctggat tgtcagtaag
     1501 atagttttta agtctatctc tatcaacctt tcttggtttt gttcctttta cttggtggtt
     1561 tagctctcct gttttctctt ttagctttaa ccagccataa atggtattac gtgagatttg
     1621 gaaaacgtgt gacgcttctg ttatactacc tgttcgctca caataagaga gaactttttt
     1681 acgaaaatct attgaatatg ccataaaaag attataccac attgtgtact atttttggtt
     1741 cattttacta taacacaaaa tagattatta ttacataaca aaaaagaggt ctaaacctct
     1801 taactcaatt actccgccag taggactcga acctacgaca tcatgattaa cagtcatgcg
     1861 ctactaccaa ctgagctatg gcgga
//
LOCUS       DAVLUM010000135         1850 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLUM010000135 DAVLUM010000000
VERSION     DAVLUM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1850
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.135"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..331)
                     /locus_tag="VYN42_002038"
     CDS             complement(<1..331)
                     /locus_tag="VYN42_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463049.1"
                     /translation="MSEVDFNEAVTYEFTSDTCQLANSIYQSLFKFFDKKNFSDDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNCNGCMGDFPHDFF
                     DIYLDHVA"
     gene            complement(389..1102)
                     /locus_tag="VYN42_002039"
     CDS             complement(389..1102)
                     /locus_tag="VYN42_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1463050.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            1664..>1850
                     /locus_tag="VYN42_002040"
     CDS             1664..>1850
                     /locus_tag="VYN42_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEV1463051.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYS"
BASE COUNT          605 a          361 c          293 g          591 t
ORIGIN      
        1 ttgctacatg atctaggtat atatcaaaaa agtcatgagg aaaatctccc atacagccat
       61 tacaattcat attgaggcta tattttcgat tagtaagata attcggaaat atatttccta
      121 ttactctaag attatctact tgtgaatccc ttctcccaat ataatcccct tctttgacta
      181 atgatggaga tttccaagta aaaattaaat cgtcagagaa atttttctta tcaaaaaact
      241 taaaaagaga ttgataaata ctatttgcta attgacaagt gtcagatgta aattcataag
      301 taacagcttc attaaaatca acttcagaca tttcaatgta ctcttcaata gtaatattag
      361 cttttttgta gtcattagct cgtctccttt aaaatgtgat cttttcaaga atatttttat
      421 ctaaacaatc cagcaagtct tggtaagaat agacttcgta agtcggctgg gcttgtgtgt
      481 gattttcgag gtgatgagga ttataccaga tagtgtcaat ccccgcatta ttgccacctt
      541 gaatgtcggc agttagagaa tctccaatca tcagcgtctt ttctttacta aatccagcaa
      601 tttgctggcc aatcttttca taaaagagag catccggctt ttgagtttgc aactgttctg
      661 agataaagac ttgattgaaa taaggtgcta gaccagattg agccaaacgt cctgtctgaa
      721 tggcagtaat gccatttgtc gcagcataca agttataatc acgctcaatg aggctgtcca
      781 agagatcatg agcgcccgat agtgtttgtc cctgctgggc gaggtaaaat tggtaacgct
      841 gggcaagaaa actaccgtct ttttcctgtc caaaatgagc aaataaacga gaaaatcgcg
      901 tgttaaccag ctcttgttta ctgattttct tcagctccaa gtctttccag agagccttgt
      961 tcataggaac gtaataatct ttataagcct gaatatccgc aactccttct tcttttagaa
     1021 gttgggtcaa agccacatcc tcagcagcat caaaatcaag aagagtgtgg tcgaggtcga
     1081 agagtagaaa tttgtagaac aatttgaggt tttcctttct gaaaattcat taagaacatt
     1141 atatcataaa gcacctcata caattaacta atttaatcac ttaaaaaaaa ttcgaacact
     1201 ttctatacaa ctgacagctc aaatctttca gaatagaaca atactaacta tcgagcaccc
     1261 cgccttcata aatatatgtg taattctaga cctagaattc ctataaacta aatgctttca
     1321 tactcttcca agtaattgat tgccttaaat tttaattttt gaaggattct aaagctagaa
     1381 tagtcccatc acaatcagtt ttgattgatt cacaatttag aaacactata gtttcactcc
     1441 tgttaaaata aaaaggaact gcataaagca atccctttct gattttgaaa tcatttaccc
     1501 ccaattattc accccaaatc taaaaaccat ccagaatcct tgccttagct tagatcctgg
     1561 atggtttctt ttttcaccca atgggtgttt tttactagac aaaaaagaat ttccccttta
     1621 tggtataagt gtagaaaaaa acacaaaaag aaaggaaact cacatgaaca gtttaccaaa
     1681 tcatcacttc caaaacaagt ctttttacca actatctttc gatggaggtc atttaaccca
     1741 gtatggtggt cttatctttt ttcaggaact tttttcccag ttgaaactaa aagagcggat
     1801 ttctaagtat ttagtaacga atgaccaacg ccgctactgt cgttattcgg
//
LOCUS       DAVLUM010000136         1769 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLUM010000136 DAVLUM010000000
VERSION     DAVLUM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.136"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            125..916
                     /locus_tag="VYN42_002041"
     CDS             125..916
                     /locus_tag="VYN42_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1463052.1"
                     /translation="MNFALNKGEIVGQVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLSITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            932..1660
                     /locus_tag="VYN42_002042"
     CDS             932..1660
                     /locus_tag="VYN42_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1463053.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAILGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
BASE COUNT          602 a          226 c          290 g          651 t
ORIGIN      
        1 aagaggcgca actttttaaa attaatgaga atcaaagaga aaaccaataa tattaatgga
       61 ggaataaaaa atgtaagtta taaatgtaag taagcattat ggtcattcaa tcattctcaa
      121 agacataaat tttgcactta acaagggtga aattgttggt caagtaggga gaaatggagt
      181 tggtaagagt acgttgatga aaattcttgt tcagaataat caaccgactt caggtaatat
      241 tataagcagt gataatgttg ggtatttaat cgaagaacca aaattatttt tatctaaaac
      301 aggtttagag aatttaaaat atttgtcaaa tttatatggt gttgactaca atcaagaaag
      361 atttagaagt ttgatccaag agttagattt aactcagtct attaataaaa aagtaaagac
      421 ctattctttg ggtacaaaac aaaaattagc tttgcttcta actctcgtta cggaacctga
      481 tatattgatt ttagatgaac cgactaatgg tttagatatt gaatcatcac aaatagtttt
      541 atcggttcta aaaaatttag ctttacatga aaatgtggga attttaatat cgagtcataa
      601 attagaagat attgaggaaa tttgtgagag ggttcttttc ttggagaacg ggcttttgac
      661 atttcaaaaa gtaggaaaag atagtcataa tttcttgttt gagatagctt tttcatcagc
      721 tacagataga gacattttca ttaccaaaca agaatttggg gatattgttc aggaagaggg
      781 actgagcatt actatgtctg ggaatattca aagtagtgag ctttttaaat tttttaacga
      841 aaactctatt aaagtagttg attttgaaac taaaaaagag acgcttaaag atatttatct
      901 aaatcgttca aaataaagga aggttataat catgaaatta aataaattta attttcttaa
      961 ggaaaatata agaaatttat attcatcagg cgtaatatat ctcagtttgc ttatctcgtt
     1021 tataccgccg atattgctta cattctttat tctaaagact caagggacat cgcttggtat
     1081 taagcatatt tcaaactttt atgctatact cggtatgtta atggctgtta tacatgctaa
     1141 tcgagtcatt agtagagatt tttcccacaa tacggtaagt ttgttttata atcaacagaa
     1201 gaatcggatg atttacgtct tgtctaattt tctatatgcc atctcagttt ccattattta
     1261 tgctttgaat ggcattgtgt tactagtcat agtaagtaaa ttgggtattc caggtgattt
     1321 aggattagat tttatagtag ctattgtagt caatacaatt ttgttagtcc tgttttattt
     1381 tctattatct tacattttct atttatacaa attgaaaagt ggcttggtat ttggtatttt
     1441 agtagcttta ctactcttta tccctaatat attaaatacg atgatgatga atactagtaa
     1501 tgatttgttt atcaaagcaa ttgaacttct tcctttttat tctttacctg tatttgtggc
     1561 ttcaaatacg atgtctatta gtcagtatct tgtgctaatc actacaatca ttttattgta
     1621 ctttttcact ctcaagaaaa gcaagaagta ttcattttag tttcatttag tattattttg
     1681 catacctaaa atacaataaa aaaatcagtc atcttggtat gctcctgctt tcactattca
     1741 acacgttttt gacttatact aggctcatt
//
LOCUS       DAVLUM010000137         1745 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLUM010000137 DAVLUM010000000
VERSION     DAVLUM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.137"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            33..1577
                     /locus_tag="VYN42_002043"
     CDS             33..1577
                     /locus_tag="VYN42_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1463054.1"
                     /translation="MLIYAATINALVLNELIAMNLERFLKLSIYQMIVWCGIIFLDWV
                     VKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLSWLNNDVQTLNDQAFKQ
                     LFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKIFASKMREVSLNLTNQN
                     EAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQRKTTVETLAGAISFFL
                     NIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGELGGQLSSIIGTKPIFL
                     KLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDKEILKNLNFCFQRNEKYLI
                     LGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNMVSNVLYVDQKAYLFEGT
                     IRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDDGRLLSGGQKQKITLAR
                     GLIRNKRIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVTHAPHPELKQYFTKIYQ
                     FPKDFI"
BASE COUNT          609 a          209 c          324 g          603 t
ORIGIN      
        1 tattaacgat atttattgtt gctggtcaat tattgctaat ttatgcagca actattaatg
       61 ctctggtgtt gaatgaatta attgcgatga atttagagcg gtttttgaaa ttgtcaatct
      121 accaaatgat tgtctggtgt gggataatat tccttgactg ggtagtgaaa aattatcagg
      181 ttgaagtgat ccaagagttt aatctagaga ttcgaaatag agttgccaca gacatctcta
      241 actctaccta tcaagaattt catagtaaat catcaggaac atatctttcg tggctaaata
      301 atgatgttca gactttaaat gatcaggctt ttaaacaact ttttttagta ataaaaggaa
      361 tttctggtac tatatttgca gttgtgactc ttaatcacta tcattggtca ttgactgtag
      421 ccaccttgtt ttcattaatg attatgctac ttgtaccaaa aatctttgca tcgaaaatgc
      481 gagaagttag tctaaattta actaaccaaa atgaagcttt tttaaaatct agtgagacta
      541 tattgaatgg atttgatgtg ttagcgtcct tgaatctttt atatgtattg cctaagaaaa
      601 ttaaagaagc aggaatttta ttaaagatgg ttatacaaag aaagacaact gtagaaacgt
      661 tagcaggcgc tattagcttc tttctcaata ttttttttca gatatctctc gtttttttaa
      721 caggctatct tgcaataaaa ggaatagtga aaattggtac tattgaagca ataggagcac
      781 taacaggtgt tatttttaca gcgctaggtg aattaggagg tcaattatcc tctattattg
      841 gtacgaagcc tattttttta aaattgtatt caattaatcc aattgagtca aataaaatga
      901 atgatatcga accaaatgag gtgaatagag attttccgtt atatgaagca aaaaatattt
      961 gctataagta tggagataaa gaaatattaa aaaacttaaa tttttgtttt caacgtaatg
     1021 aaaagtattt aattttaggt gaaagtggaa gcgggaaatc tacattatta aaattattga
     1081 atggcttttt gagagattat agtggagaat tgcgattctg cggggatgat ataaaaaaaa
     1141 cctcctattt aaatatggtt tcgaatgttc tatatgtaga tcaaaaagct tatttgtttg
     1201 aaggtacgat tagagataat attttattgg aagaaaatta tactgatgaa gaaatactac
     1261 agtctttaga gcaagttggt ttgagtgtaa aagattttcc taataacatt ttagattatt
     1321 atgttggtga tgatgggaga ttactatcag gagggcagaa acaaaaaatt actttagcta
     1381 gagggctaat tagaaataag agaatagtat taattgacga gggaacttct gctatcgata
     1441 ggagaacttc gttagcgatt gaacgtaaga tattagatag agaggatttg actgtcatta
     1501 ttgttaccca tgctccgcat ccggaactta aacaatattt tactaagata tatcaatttc
     1561 caaaggattt tatttaagaa tataggggag ggaaacatga gattctattg tgaagcttat
     1621 gaggtaatta ctgaagagaa aaaagtatca ttttttatgt agatgaaaaa cccttaaggt
     1681 atctgttatt tgactatata tttctactag ttctagctaa aaaaaatatc ccaatcttat
     1741 gaact
//
LOCUS       DAVLUM010000138         1733 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLUM010000138 DAVLUM010000000
VERSION     DAVLUM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.138"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..785
                     /locus_tag="VYN42_002044"
     CDS             <1..785
                     /locus_tag="VYN42_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1463055.1"
                     /translation="TDNKKYPFVVKPRLGAGSIGVTIIQNKSELKDFISSPLSQNLMV
                     ETFTNGEMYHVDGLFKDNEMLLYSVSKYFNDCLSFKTNTPLGSYMIDDSNPLSRKLYD
                     ATLKVLTKIPTPNHTIPFHAEFFVDGEKVTFCEIASRVGGGLINDSFKLLTNIDLQKT
                     FVKSQIGIDYLNIIKSDKRTAWITIPPKEGELLSVNLYKDSWVEKVNFDETSIGRRYS
                     GGDYSASALIAYLISGTDEDDLKNKILHIIEWQDKNTIYKEK"
     gene            821..1450
                     /locus_tag="VYN42_002045"
     CDS             821..1450
                     /locus_tag="VYN42_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1463056.1"
                     /translation="MFILGSGDQGLAVLSIYEGEVEGLVDIFEEGRFIGCKILDKTVL
                     GGLKWFESLLLTLDRKPRAIVAFGDNFKREEIFCSYKNKVEYINVICNSARIFKHSFL
                     GKGNFIGTNVTIQALVEIGDNNIINSGSIVSCNCKIGNNVNISPGVILSGNVKIDDNV
                     FIGAGATIRDAVSIGFGAIIGAGATVIHNVPENAVVVGTPGKIIKYRSV"
BASE COUNT          606 a          195 c          334 g          598 t
ORIGIN      
        1 ttactgataa caaaaaatat ccatttgtag tgaaacctag acttggtgca ggatcaattg
       61 gtgtaacaat aatacaaaat aaatctgaat taaaagattt tattagtagt cctctaagtc
      121 aaaatttaat ggttgaaact ttcacaaatg gggagatgta ccatgtggat ggtttattta
      181 aagataatga aatgctgtta tattctgttt caaaatattt caatgattgt ttatcgttta
      241 aaactaatac accgctaggc tcatatatga ttgatgatag caatcccctt tcgagaaaat
      301 tatatgatgc aacattaaag gtattaacta aaataccgac tcctaatcat acaattcctt
      361 ttcatgctga attttttgta gatggtgaga aggttacttt ttgcgaaatt gcttctagag
      421 taggaggagg gctgataaat gattccttca aattactaac taatattgat ttacaaaaaa
      481 cattcgtaaa aagtcaaata ggaattgatt atttaaatat aataaaatct gataagagaa
      541 cagcttggat aacaattcct cctaaagaag gagaattact atctgttaat ttgtataaag
      601 attcatgggt tgagaaagtg aattttgatg agacctctat tgggagaaga tatagtggcg
      661 gtgattatag cgcttctgct cttatagcat atttgattag tggaactgat gaagacgatt
      721 tgaagaataa aattttacat attattgagt ggcaagataa aaatacaata tataaagaga
      781 aataatcata agtttgtttt aaaaattgtg ggtaaaggat atgtttatac taggttcagg
      841 agatcaagga ttggcggtat tgtcaattta tgaaggtgaa gttgagggat tggtagatat
      901 ttttgaggaa ggtcgcttta ttggttgcaa aatcttagat aaaactgttt tagggggatt
      961 aaaatggttt gaaagtttac tcttaacact tgataggaag cctagagcaa ttgttgcatt
     1021 tggtgataat tttaagcgcg aagaaatatt ttgttcatat aaaaataagg tggagtacat
     1081 taatgttata tgtaattccg cgagaatttt taaacattct tttttaggaa aaggaaattt
     1141 tattggtacc aatgtgacta ttcaagcact tgtagaaatc ggtgacaaca atattataaa
     1201 ttctggtagt attgtttcat gtaattgtaa aattggtaat aatgtaaata tttccccagg
     1261 tgttatatta tctggaaatg ttaaaattga tgataacgtt tttattggtg caggagcaac
     1321 aattagagat gcggtaagca ttggctttgg tgctataatt ggtgcaggtg ctaccgtaat
     1381 acataacgta ccggaaaatg ctgtggtagt aggaacacca gggaaaataa taaaatatag
     1441 atcagtttga agagaaactc ttcattgcca tataacttaa gtttcatcgc atgtcagtaa
     1501 tctcataagg aattagttag atattagtgt tagctcctag gtttcaactg atctaatgat
     1561 taatgtaaga attcttaaag tatacatttc gacactgtaa ttatgacaga agtattttgg
     1621 gatagttggc tcaacaaatt gaaatctttt caacttgtga atttttagga ttatcttatt
     1681 tgactttatg agtattgttt acgttcaata ctttacaata acatattaag gtt
//
LOCUS       DAVLUM010000139         1728 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLUM010000139 DAVLUM010000000
VERSION     DAVLUM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1728
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.139"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..>1728)
                     /locus_tag="VYN42_002046"
     CDS             complement(<1..>1728)
                     /locus_tag="VYN42_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV1463057.1"
                     /translation="NRLTEGLRTKVDISALNVTAENIRQSVKSLETDTQNKLNQKLSQ
                     AEFEVRAGSIRQEILNATKDKASKSELTQTAEELASKIASVHLGRRNLLKGTKELARY
                     KPVSEYNGFKVIRTVAGATRYQDSYVERTVIPTAGTEYIAIFYARASENDYPVRCHFY
                     NPNTVVSSENSSGYKSRSSDGLSIIRLSTDWQLCWVKWTQTATDQAKTVIIGRHGPQV
                     GGKEGVWVEICAPAIFEGNLAGDWSPAYEDQDERVSAVESNFKQRADSLEAGVSRLTE
                     GLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATK
                     DKASKSELTQTAEELSSKIASVQVGGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKT
                     IDVSDSPVTGFDKAIRLTSSNARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQT
                     YWQVNDNSGISPIFTLKDENWTKLSFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQ
                     LEDGSLATSSKEAPEDIEGQISTVESTFKQRANSLDAGVRSLTEGLRTKVDISSLNVT
                     AENIRQSVKR"
BASE COUNT          387 a          449 c          357 g          535 t
ORIGIN      
        1 cctcttcaca gattgccgga tattttcagc agtcacattg agtgagctga tatccacttt
       61 ggttctaagc ccttcagtca agcttctcac accagcgtcg agcgagttgg ctcgttgttt
      121 aaaggtcgat tctactgttg aaatctgacc ttctatatct tcaggagctt cttttgagct
      181 tgttgccaaa cttccgtctt ccagctgggg cgcaagaaca tctaaatatt ctccgacttc
      241 agcatttacg agatacacat agccaattga tgcgactcca gccctatttc tagcgctagt
      301 aaacgatagc tttgtccaat tttcatcctt taatgtaaag atgggcgaaa tacccgaatt
      361 atcattgact tgccaataag tttgtagctt gaccttttga cctcttctgc ctttgaccca
      421 acaagacatc gtgtatgtgc cttgcgagat ataaaatcca tcttgagcaa tacctatttg
      481 gtctctagca ttgcttgagg tcaatcgtat cgctttatca aagccagtta ctggactgtc
      541 tgatacatca atcgtctttg ccgtcccagc gcctgacggt ctaaaagtac ctgatgccca
      601 caatcctctg gctagcatca tgcgctttgt accccggata taattcctac ccccgacctg
      661 cacactcgct atcttactag agagctcctc agctgtctgc gtgagttctg acttgctggc
      721 tttatccttg gttgcattca ggatttcctg acgaatagag ccggctcgca cctcaaattc
      781 agcctgactc aacttctgat ttagcttgtt ctgcgtgtct gtctcaagac tcttcacaga
      841 ttgccggata ttctcagcag ttacgttgag tgagctgata tcggctttgg ttctaaggcc
      901 ttcagtcaga cggcttacac cagcttcgag tgaatcagca cgctgtttaa agttggattc
      961 gaccgctgag acacgttcgt cttggtcttc gtatgctggt gaccagtcac ctgcaagatt
     1021 tccctcaaaa atggcagggg cgcagatttc aacccatacc ccctctttac cgcctacttg
     1081 agggccatgg cggccaatga tgaccgtctt ggcttgatct gttgcggttt gggtccattt
     1141 aacccagcac aactgccagt ctgtcgagag acggataata gacaagccat ctgacgacct
     1201 tgacttatat ccgctgctgt tttctgatga tacaaccgtg ttaggattgt aaaaatgaca
     1261 gcgcacagga tagtcatttt cactggctcg tgcataaaag atagctatat actctgtccc
     1321 agccgttggt ataacggttc tttccacata gctatcctga tatctagttg ctcctgcgac
     1381 tgttctgata actttaaaac cattatattc actaaccggc ttgtatctcg caagctcttt
     1441 tgtgcctttc agcagatttc tgcgccctaa gtgcacactc gctatcttac tagctagctc
     1501 ctcagctgtc tgcgtaagtt ctgacttgct ggctttatcc ttggttgcgt tcaggatttc
     1561 ctgacggata gagccggctc gcacctcaaa ttcagcctga ctcaacttct gatttagctt
     1621 gttctgcgtg tctgtctcaa gactcttcac agattgccgg atattttcag cagtcacgtt
     1681 gagtgcgctg atatccactt tggttctaag gccttcagtc agacgatt
//
LOCUS       DAVLUM010000140         1672 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLUM010000140 DAVLUM010000000
VERSION     DAVLUM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.140"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            147..833
                     /locus_tag="VYN42_002047"
     CDS             147..833
                     /locus_tag="VYN42_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1463058.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            834..>1672
                     /locus_tag="VYN42_002048"
     CDS             834..>1672
                     /locus_tag="VYN42_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1463059.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSA"
BASE COUNT          545 a          232 c          319 g          576 t
ORIGIN      
        1 tacgccttaa atgctaaaat atttctataa attaatttaa ctttcctgat agggctgttc
       61 atatcttatt tcaattcact atataaataa aattgtagta gatgttattg aattagtaaa
      121 aaaataaaaa aacggaggtt ttctgaatgg aaactaaaaa aattaaaaat ttaaaaggtc
      181 aaataattgt ttcctgccaa gcgttagaag gagagccact ttatactcca aatggaggag
      241 tgatgccgtt attagcaaaa gccgcctttc aagcaggcgc taaaggtatt cgtgctaatt
      301 ctgtccgcga tatttcagaa ataaaagaag aagttgactt accaattata ggtatcataa
      361 aaagagatta cgatggcttt gaacctttta tttcagcaac tatgaaagag attgatgaat
      421 tagttagtga aggagtagac attttagctt tggattgtac taatcgttca agaccaggtt
      481 atgataatat tactgacttt attcatgata ttaaagtcaa gtatccaaac caattattaa
      541 tggctgatat ttctactttt gaagaaggga aagtagctgc tgaatcggga gtagattttg
      601 tgggtacgac attatctggt tatacaccat atagccctaa aaaagataat cctgattttg
      661 agttagttga aagattggta aaagagcttg acgtaccagt tattgctgaa ggaagaataa
      721 gtactccgga acaagctaga aaaatgttag atttaggtgc ttacgcagtg gttgttggag
      781 gagctatcac tcgtcctttg gaaatagcga agaagtttat tgaggtagtt tagatgaatc
      841 aagaaatatt aaaaaagagt aagattcaat tgacagttga acatattcaa aaatattgga
      901 ttttatattt aatgatgatt ccagcaactg ttctactaat tttatttacg tatggaccaa
      961 tgtacggcat tattatggcc tttcaagact ttactgtctt caagggatat actggaagtc
     1021 catttgtcgg tttaaaacat tttcaaagat tgttctcaga tcctttgttt tatagattgt
     1081 tcaagaatac gttcatggta ggggttttag actttttatt ctctttccca gctccgctta
     1141 tttttgcact catattaaac gaagtcagaa aagtaagatt taagagtgta gttcaatcta
     1201 ttagttatct tcctcatttt attcccctag tggttatggt tggtattatt tttgaactat
     1261 ttggttcata tggtattatt aacagtttac tttcatcact tggaatggag ccaataagtt
     1321 tctttacaaa atctgaatgg ttcttgcctc tctacattgg ttcaggagta tggaaaacaa
     1381 taggttgggg ttctatcatt tatatgggag cattaaccaa tatagattca actttatatg
     1441 aagcagcaga tatggacggg gctaatagat ggcacaaaat gtggcatgta actctaccaa
     1501 gtttaagacc tacagtagtt actttgttta tactaaatgc tggtggtatc atgcaagtag
     1561 gatttgaaaa ggtattcttg atgtctagtc ctgcaacata tgaagtatct gatgtattat
     1621 ctacttatgt ttatagacaa ggtattttaa attctgattt cagttactca gc
//
LOCUS       DAVLUM010000141         1626 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLUM010000141 DAVLUM010000000
VERSION     DAVLUM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1626
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.141"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            212..1573
                     /gene="dnaA"
                     /locus_tag="VYN42_002049"
     CDS             212..1573
                     /gene="dnaA"
                     /locus_tag="VYN42_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1463060.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
BASE COUNT          554 a          281 c          285 g          506 t
ORIGIN      
        1 gctgttcttt tattttttta tctcacaagg ttatccacta tgtttttcga taaaaagctt
       61 aataaatcaa taatttcttc ttttatcccc aacctgtgga taaagtttag taacattgtg
      121 gattattttt cacagcttgt ggaaaattct tgctatctat ggtaaaatat ctctagtatt
      181 aaacttttaa atagtaaagg aggagaaagg attgaaagaa aaacaatttt ggaatcgtat
      241 attagaattt gcacaagaaa gactgactcg atccatgtat gatttctatg ctattcaagc
      301 tgaacttatc aaggtagagg aaaatgttgc cactatattt ctacctcgct ctgaaatgga
      361 aatggtctgg gaaaaacaac taaaagatat tattgtagta gctggttttg aaatttatga
      421 cgctgaaata actccccact atattttcac caaacctcaa gatacgacta gctcacaagt
      481 tgaagaagct acaaatttaa ctctttatga ctatagtcca aagttagtat ctattcctta
      541 ttcagatacg ggattaaaag aaaagtatac ctttgataac tttattcaag gggatggaaa
      601 tgtttgggct gtatcagccg ctttagctgt ctctgaagat ttggctctga cctataaccc
      661 tctttttatc tatggaggac caggccttgg taagactcac ttattaaacg ctattggaaa
      721 tgaaattcta aaaaatattc ctaatgcgcg tgttaaatat atccctgccg aaagctttat
      781 taatgacttt cttgatcacc taagacttgg ggaaatggaa aagtttaaaa agacctatcg
      841 tagtcttgat cttttgttaa tcgatgatat ccagtcactc agcggaaaaa aagtcgcaac
      901 tcaggaagaa tttttcaata cctttaacgc ccttcatgac aagcaaaaac agattgtcct
      961 aacgagtgat cgtagtccaa aacatctaga agggctcgag gagaggcttg tcacgcgttt
     1021 tagttgggga ttgacacaaa ctatcacacc ccctgacttt gaaacacgta ttgccatttt
     1081 acaaagtaaa acggaacatt taggctacaa tttccaaagt gatactctag aatacctagc
     1141 tgggcaattt gattcaaatg ttcgagatct tgagggagcc atcaacgaca tcactttaat
     1201 tgccagagta aaaaaaatca aggatatcac tattgatatt gctgcagaag ccattagagc
     1261 ccgcaaacaa gatgttagcc aaatgctcgt catcccaatt gataaaatcc aaactgaagt
     1321 tggtaacttt tatggtgtta gtatcaaaga aatgaaggga agtagacgcc ttcaaaatat
     1381 tgttttggcc cgtcaagtag ccatgtattt atctagagaa ctaacagata atagtcttcc
     1441 aaaaattggg aaggaatttg ggggaaaaga tcataccaca gtcattcatg cccatgccaa
     1501 aataaaatct ttgattgatc aagacgataa tttacgttta gaaattgaat caatcaaaaa
     1561 gaaaatcaaa taatttgtgg ataactttta gttttttatc ttttttatcc acatttttta
     1621 aacaag
//
LOCUS       DAVLUM010000142         1575 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLUM010000142 DAVLUM010000000
VERSION     DAVLUM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.142"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..239
                     /locus_tag="VYN42_002050"
     CDS             <1..239
                     /locus_tag="VYN42_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEV1463061.1"
                     /translation="KHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQLLKLSSLYAY
                     SELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            complement(402..1037)
                     /locus_tag="VYN42_002051"
     CDS             complement(402..1037)
                     /locus_tag="VYN42_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1463062.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGDSLSQIIHTSLN"
     gene            complement(1108..1407)
                     /locus_tag="VYN42_002052"
     CDS             complement(1108..1407)
                     /locus_tag="VYN42_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1463063.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYYDYD"
BASE COUNT          507 a          309 c          282 g          477 t
ORIGIN      
        1 tcaaacatct agctggaggt gacttccaaa ctttaacaat caaacgcttc cgccatcttt
       61 ttcttcacgt ggtgggaaaa tgtgttcgaa caggacgcaa gcagctcctc aaattgtcta
      121 gtctctatgc ctattccgaa ttgttttcag cactttattc taggattaga aaagtcaacc
      181 tgaatcttcc tgttccttat gaaccacctg gaagaaaagc gtcgttaatg atgcattaaa
      241 gaacagtcga gatgaaaaaa tcgtgtgacg caccaaggga ggagtctgcc cttttgagga
      301 aatctagcga ggaaaaacga tactggaaca gcagaaagta aaactgacct catgaggagg
      361 aagaaagtgg ctcatgaggt caggggtttt gtaagttaca tctagttgag agaggtatga
      421 atgatttggg ataaagaatc ccccatgatg gataagagag tctgaccaga aaagagtttt
      481 atacctgctg ctctcatttc cttaatccga gtgataatca ctaaagcaaa gaaagataag
      541 ccaaatattg ctaaactaat taaaataagg ggatttagta atattcgaaa agcaagaaaa
      601 tagggcggta tctttcggtc agcacttgct ttataaccca aatctcctaa tttatcggca
      661 agcttttctt tcgtcaagga gcctgacaaa aggagataac tatttagcgg atcactacgt
      721 tcacgacttt cttggctagc ttcttggaat tcttttggta aagttccctg accataagtt
      781 gcataagtaa agtgagtcgt cccatcctta ctcggctcta caattcttct agctattaaa
      841 ctctgttctg agtttgcaaa attctccaat tcctgttcaa atacctcacg cgtcggttcc
      901 tgagtatctt ttttgacacg aagtaaagaa acggaatcat agcttgcata taaatattgt
      961 ggcgcacgta agacaataat ccaagcaagg aagaagctga gaaaaaaagt tgataataat
     1021 atgaatagtt tcttcatagt agactccttg taaacaaaat tccccctgta atttcttaca
     1081 aggggaatta tctaagaaaa ctaaatatta gtcatagtca tagtaaaatg ctacttgttc
     1141 tccccattta gtccaaatcc atgcgtagga ggtttttcca gcaggagctt ctcctttatc
     1201 agaatgacca tcccatctgc tcacgatgga tgaataatga tattttttac catgatagta
     1261 atttgaaaaa gcccaaccac ctcctgaacc ttctccatat gtccatactc ctccatctgg
     1321 atattgtaca gcagctgatg cagctcccaa taatgtaaaa cttgaaataa gaactagagc
     1381 aagtaatcta tgttttttcg ttttcatttt attttttctt tcaaaaaaag cacaccttga
     1441 gcaacaatgc aacaaaataa accctcctct ctcttttgtt gaaaccgctt tcttatgtga
     1501 taagaataac atttttatta tttgttgtca aggaaaaaat cgaatttttt agatatttta
     1561 ctatattacc tctat
//
LOCUS       DAVLUM010000143         1545 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLUM010000143 DAVLUM010000000
VERSION     DAVLUM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.143"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(1..152)
                     /locus_tag="VYN42_002053"
                     /pseudo
     CDS             complement(1..152)
                     /locus_tag="VYN42_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(501..893)
                     /gene="rpsI"
                     /locus_tag="VYN42_002054"
     CDS             complement(501..893)
                     /gene="rpsI"
                     /locus_tag="VYN42_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1463064.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(912..1358)
                     /gene="rplM"
                     /locus_tag="VYN42_002055"
     CDS             complement(912..1358)
                     /gene="rplM"
                     /locus_tag="VYN42_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1463065.1"
                     /translation="MNKTTFMAKPAQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
BASE COUNT          445 a          295 c          306 g          499 t
ORIGIN      
        1 acctttttga ggtgcttttt gatatgagcc catgttttct caataggatt gtactcaggt
       61 gagtagggag gaagaggtaa aagtttatac ccaaactctt cacacaagag ttctagcttc
      121 cccattctat ggaatcttgc attatccata atatagtaga ttgaaagtag aatagtacac
      181 ctctacttct aaaacattgt tagaattcga tttgactatc ctcgatttgt cctattctta
      241 tttcatatta ctataaaaat aaggtaaact tttcaaaaaa gcacgaaaaa agcacccata
      301 aggtaaactt ttgagtgctt tgaaacattg atataatcgt attgattaac gttttgaggc
      361 aactgacctt gtcaggttgc agccacattt gtaagcgact aaagtcgcaa caactgtgtc
      421 aattgcacca atttaataag aaagtataaa aaaagaacac cccgaaaggt gctctgtata
      481 agtatagtaa ttctttcgaa ttaacgttta ctaaattgtg atgctttacg agctttctta
      541 agacctggtt tcttacgttc aactttacgt gagtcacgtg taagaagtcc tgcgcgtttc
      601 aatgaatcgc ggaagtctgg gtctacttga agaagggcac gagcgatacc gtgacggata
      661 gctcctgatt gaccagcgta tccaccacct acaacgttaa cgaaaacgtc gtatgaacct
      721 acagttgaag taactgcgaa tggttggttg atgacaagac gaaggtcagc gtgtgggatg
      781 tactcttcaa catctttttt gttaacagtg attttaccag ttcctggaac aaggcgaacg
      841 cgtgcaacag cgtttttacg acgtccagta cctgcatatt gtgcttgtga catactttat
      901 tgttcctttc cttagataag ttctgaaatg tcaagaactt ctggttgttg tgcagcatga
      961 gtgtgctcag ctccaacaaa tactttcaac ttcatacctt gagcgcgtcc aagtgtattg
     1021 tgtggaagca tacctttaac tgatttctca atcaaacgta ctgcattttt agaacgaagt
     1081 tcacctgcag agatttgttt caatccacct gggtggtttg agtgagtgta gtagatttta
     1141 tcagttgctt ttttaccagt caatttaact ttttcagcat tgataacaat cacgaagtca
     1201 cctgtatcag tgtgtggtgt aaatgttggt ttgttttttc cgcgaagtac gctagcaact
     1261 actgcagaaa gacgtccaag tggtacatca gttgcgtcaa ctacgtacca tttacgttca
     1321 acttgggctg gtttagccat aaatgttgtt ttgttcatga tttctcctat atatagttcg
     1381 atttttgttt acggtgatgg gtgttccttc ccatcgaaaa gtatttggaa ggttccgggg
     1441 cctttcaaat ggggtaaaca ataccgccta ctatcatacc aaatttcacc cctaaaagtc
     1501 aatagatatg aaaaatattt ttcggtaact tctcaaagta actga
//
LOCUS       DAVLUM010000144         1526 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLUM010000144 DAVLUM010000000
VERSION     DAVLUM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.144"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            24..1247
                     /locus_tag="VYN42_002056"
     CDS             24..1247
                     /locus_tag="VYN42_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1463066.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKNLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
BASE COUNT          550 a          281 c          204 g          491 t
ORIGIN      
        1 aaataaacca aaggaggaaa caaatgatta caaaacaatc agccttttta caaaatagag
       61 ccactatact ggagtttcta tatcgaaatc cagcaacatc ccgtacagat attgttaatg
      121 aaacaggact tactccagca acaacgacta acatcataaa agagctaagc gaacagtccc
      181 tcatatacga aactggtgat gaatttagcg agttttccgg atctggaaga cgtagaaaaa
      241 ctatttctat cacagataat attccgtatg ttgttggagg tattgaaata aacgtcctag
      301 gtatctttct cagtctatgt gacttacaag ggaaaactct tttcgagaca gaaattttga
      361 atgaagatta tcctatttca gaaatcaatt ccaccattac caatatgata aaaacagcta
      421 tagagtacgt ccctttggag acaaaattac ttggatttgg cttatcaata cctggacatt
      481 ataacaaaga ctccggaagt atcattacaa acaaccccat atgggaatct tttaatttat
      541 taaatgtaat taaaagattc aattttcctt ttattgtaaa aaataatatc gattgtatgg
      601 ctataggaca ataccttttt aatccacaca atacccccga taactttatt ttcctacacg
      661 ctggattagg tatttacact tcctttttca caaaagaaaa aataggagcc tctaaaaatc
      721 cttatatcgg agaaattgga cacaccattg tcgaattgaa tgggcaatat tgtgaatgcg
      781 gaaaaaaagg ttgtttacaa acatatattt ctgatgcttg gttaatcaaa catgctcaat
      841 tattatttaa aaattctcaa ctaactgtac taaaaaacct tgtaaaaact gaaaaagaca
      901 ttcatttaga tactctttta acagcttaca acttaggcga ttctgcttta cgccaacaaa
      961 ttgataaagg agtcaattta ttggccactt ctattgcaaa tcttctcctc atcaatcctg
     1021 ctgataaaat ctatatcaac agtcaattgc ttaattatca acctttcact catgaagtca
     1081 gggataaaat ccaagatcaa ctccactttg ttccctttac tcgtaatata gaaattgaaa
     1141 ttttacctta caacaaacat cgtggaagta taggagcttg tgcattagct atcgttgctt
     1201 ttttcataga gcatagcaat gtattacaag atattatttc accttaatat atattagaaa
     1261 tctatagacc tgtttaaatc aactataacc tgtagtaaat atctcgtatt tagacaatat
     1321 gaaaacaaga cgacttccat ataggaaacc gccttctctc tatgttgagt gatttatatt
     1381 aaaataactt ttcttctagc tgcattttat tattgtaaaa acattcatca taacccccag
     1441 aacttaaata acaattttta ttcaagatac atactcctag aataaacttt atatgaaatt
     1501 ctcatttttg tttttacaat tctcct
//
LOCUS       DAVLUM010000145         1518 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLUM010000145 DAVLUM010000000
VERSION     DAVLUM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.145"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            217..1419
                     /gene="rpsA"
                     /locus_tag="VYN42_002057"
     CDS             217..1419
                     /gene="rpsA"
                     /locus_tag="VYN42_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1463067.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT          474 a          247 c          353 g          444 t
ORIGIN      
        1 gtaaggcaag ggactttgac tccctcatgc gttggttcga atccagctac cccagttctt
       61 aggtaataat caagataaaa agcaaaatat cttagggtat tttattttta taattgaaag
      121 acgtgaatga tatgaacatg tccttgctgg tgcttaggaa aaaaattata agtatgtcaa
      181 gtttaagaaa aacttgattg ttggaggatt ttttagatga acgaatttga agatttgcta
      241 aatagcgtta gtcaagttga gactggtgat gttgttagtg ctgaagtatt gacagttgat
      301 gcgactcaag ctaacgttgc aatctctgga actggtgttg aaggtgtctt gactcttcgc
      361 gaattgacaa acgatcgtga tgcagatatc aatgactttg ttaaagtagg agaagtattg
      421 gatgttcttg tacttcgtca agtagttggt aaagatactg atacagttac ataccttgta
      481 tctaaaaaac gccttgaagc tcgcaaagca tgggacaaac ttgttggtcg cgaagaagaa
      541 gttgttactg ttaaaggaac gcgtgccgtt aaaggtggac tttcagtaga atttgaaggt
      601 gttcgtggat ttatcccagc ttcaatgttg gatactcgtt tcgtacgtaa cgctgagcgt
      661 tttgtaggtc aagaatttga tactaaaatc aaagaagtta acgctaaaga aaaccgcttc
      721 atcctttcac gtcgtgaagt tgttgaagca gctactgcag cagctcgcgc tgaagtattc
      781 ggtaaattgg ctgttggtga tgttgtaact ggtaaagttg ctcgtatcac aagcttcggc
      841 gctttcatcg accttggtgg tgttgacgga ttggttcact tgactgaatt gtcacatgaa
      901 cgtaacgtat caccaaaatc agttgtaact gttggtgaag aaattgaagt gaaaatcctt
      961 gatcttaacg aagaagaagg acgtgtatca ctttcactta aagcaacagt accaggacca
     1021 tgggatggcg ttgagcaaaa attggctaaa ggtgatgtag tagaaggaac agttaaacgt
     1081 ttgactgact tcggtgcatt tgttgaagta ttgccaggta tcgatggact tgttcacgta
     1141 tcacaaattt cacacaaacg gattgaaaat ccaaaagaag ctcttaaagt tggtcaagaa
     1201 gttcaagtta aagttcttga agttaacgca gatgcagaac gcgtgtcact ttctattaaa
     1261 gctcttgaag aacgtccagc ccaagaagaa ggacaaaaag aagaaaaacg tgctgctcgt
     1321 ccacgtcgtc caagacgtca agaaaagcgt gatttcgaac ttccagaaac acaaacagga
     1381 ttttcaatgg ctgatttgtt tggtgacatc gaactttaat caaattgaaa attcacaaaa
     1441 tcctttgttt actaaacaag ggatttttct ggctctttgt caactgtagt gggttgaaga
     1501 aaagctaagc tcgagaaa
//
LOCUS       DAVLUM010000146         1507 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLUM010000146 DAVLUM010000000
VERSION     DAVLUM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.146"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            11..247
                     /locus_tag="VYN42_002058"
     CDS             11..247
                     /locus_tag="VYN42_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEV1463068.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKSISHEEMMRRYG"
     gene            240..971
                     /locus_tag="VYN42_002059"
     CDS             240..971
                     /locus_tag="VYN42_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1463069.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(1082..1165)
                     /locus_tag="VYN42_002060"
     tRNA            complement(1082..1165)
                     /locus_tag="VYN42_002060"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1129..1131),aa:Leu,seq:caa)
     gene            complement(1175..1246)
                     /locus_tag="VYN42_002061"
     tRNA            complement(1175..1246)
                     /locus_tag="VYN42_002061"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1212..1214),aa:Gln,seq:ttg)
     gene            complement(1257..1329)
                     /locus_tag="VYN42_002062"
     tRNA            complement(1257..1329)
                     /locus_tag="VYN42_002062"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1294..1296),aa:His,seq:gtg)
     gene            complement(1344..1414)
                     /locus_tag="VYN42_002063"
     tRNA            complement(1344..1414)
                     /locus_tag="VYN42_002063"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1380..1382),aa:Trp,seq:cca)
     gene            complement(1419..1499)
                     /locus_tag="VYN42_002064"
     tRNA            complement(1419..1499)
                     /locus_tag="VYN42_002064"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1463..1465),aa:Tyr,seq:gta)
BASE COUNT          521 a          271 c          274 g          441 t
ORIGIN      
        1 tggctgttat atgaataatg ttgttactac acaaatttct attcaactta gtcaagagtt
       61 aaattcttta ttaaatgcta ttgttgaaga aaataataca acaaagactg actttattag
      121 acaagctgtt atagagaaaa ttgaagatat gtatgatatt aaggtcgctg atgaagctta
      181 taaaaaatgg gttgaatgtg gcaaaaaatc tatctcacat gaagaaatga tgagacgcta
      241 tggctaaatt atacgcaata tctgatatac atggatactt ggatgaattc agagacgctc
      301 tcaataaagt aaatttaaac gataaagata atcgcctatt tttactagga gattatcttg
      361 ataatggact tcaatctttt caagtcattt ccaaaataat cgaacttgag gaggtttatc
      421 ctaatcaaat tattactctt ctagggaatc atgaagaatg gttttatgat tggttgattt
      481 tagataaacc tactgcttca gcatttccag aaacaataaa aagcttcttc tctccagagg
      541 aattgaacta tatttttaaa tcgaatgcta acaactttga aacaggtgtt agaaatgaaa
      601 ttaaaaataa tatcaaattc aacccattta taaactggtt taaaaagcga tatagggata
      661 aacgctatta tgaaactgat acccaaattt ttgttcatgc aggcattgat gaagaagcag
      721 gaatgctttg gaaagaacta acgagttcaa agatatttac aaacaaattt ccaattacca
      781 ctggtagatt tcataaagct attatttcgg gccatattgc ttcttgggaa gtagctaaag
      841 atagaagata cctaggtaag atttactatg atagtaaaag tcattactta attgatggag
      901 atgtaacgaa tagcaaaaca atacctgttc tttactatga tacaattacc caaaaatatc
      961 actttctata acttttaatc atgtgctttt atatgaaatt agtaattatt agtaacaatt
     1021 ccaagaaatt tcttatgaca taacaaaaag acaaggtcct aaaaccttgt ctttaatact
     1081 ataccggcgg ccggggtcga accggcacgt ccttgcggac actggatttt gagtccagcg
     1141 cgtctgccaa ttccgccacg ccggcaaata gtaactgggg tagctggatt cgaaccaacg
     1201 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaatat aaaataggcg
     1261 agtgatgggg atcgaaccca cgcatgccag agccacaatc tggtgtgtta accacttcac
     1321 cacacccgcc ataattctat taacacgggc agtaggaatt gaacccacac tgaaggtttt
     1381 ggagacctta gttctacctt taaactatgc ccgtaaaatg gaaggggagg gattcgaacc
     1441 cccgaacccg aaggagcgga tttacagtcc gccgcgttta gcctcttcgc tacccttcca
     1501 aaatata
//
LOCUS       DAVLUM010000147         1496 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLUM010000147 DAVLUM010000000
VERSION     DAVLUM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.147"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            482..1081
                     /locus_tag="VYN42_002065"
     CDS             482..1081
                     /locus_tag="VYN42_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463070.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPIFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            1224..1394
                     /locus_tag="VYN42_002066"
                     /pseudo
     CDS             1224..1394
                     /locus_tag="VYN42_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          517 a          219 c          295 g          465 t
ORIGIN      
        1 gcctcataat ccagcttagc gataatttct ttgtgggtat ccatattgat gatatctaga
       61 atcttgatgt ttgggtcttt aatatcgagc agttttgtga taaaatgtaa ttgttccata
      121 tgattctttc taatgagttg ttttgtcgct tttcattata ggtcatatgg gacttttttt
      181 ctacacaaaa ataagctcca taatatccat aggggattta cccactacaa atattataga
      241 gccgttaata tttggagaag aggatggcca tcttctccat ttttatgtgc agagttatag
      301 tgacttgatg ctgggaaagt acactgtgac tgctaatact caatgaaaat caaagtgcaa
      361 actaggaagc tagccgcagg ctgtacttga gtacgtcaag gtgaagctga cgtggtttga
      421 atttgatttt cgaagagtat aaaacattcc tagaagttgc tttgatttcc ctaatctatt
      481 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      541 agttcattta gatgtaagca ttgaagataa tcagggaggt agtgggcata atttcagttc
      601 tgtttcaagt agctcacaaa cagctaaata tgaagaaact ggttataata acaattcatc
      661 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      721 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      781 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaaaaagaaa taacagtaaa
      841 aattgtttct gctaaaccga catatccaga caaaatctta gtgaaaaatc ctgataatat
      901 aaaagataca gaaaaaaatg ccattattga aaaattgaaa gaggcaaata aaaatcatcc
      961 agcaggagct ccaatctttg ctaaaggtga aggagagcat gcaaatgata ttgtagcaac
     1021 ttattcagat ggtacaactt attatgtacc gttaaatgat gtgacaaaat atgcgaggta
     1081 gtggttgtac cactcactta ttcacctccc cgtgatttgt agtagtgata ggctttctaa
     1141 ctattattat aaaacaaaat aaagagcaca acactttttc attctgtgtt gtgccttgag
     1201 tgaaacgaaa ggaatgaatt ataaatatga aaagtatagt cactagcata gatgagcgct
     1261 tgcgtactcg cctacgagtg attatctgga agcaatggaa gaagaaatcg agacgattat
     1321 ggggattgct taagttaggg gttcctaaat ggatagcaga taaggtatct ggctggggcg
     1381 accactatca attatagtaa aatgaaataa gaataggacg aatcgatcag ggaagtcaaa
     1441 tcgatttcta acaatatttt agaagtagag gtgtactatt ctagtttcaa tctact
//
LOCUS       DAVLUM010000148         1469 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVLUM010000148 DAVLUM010000000
VERSION     DAVLUM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.148"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(510..>1469)
                     /locus_tag="VYN42_002067"
     CDS             complement(510..>1469)
                     /locus_tag="VYN42_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1463071.1"
                     /translation="KVDECKNNEKYSSAGHTFCWKKENSTYAEGLYWFYEGGSFIIDI
                     HDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSLCTFDFDNIKDD
                     FVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQIILTKALERVAM
                     EILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKALEDVARFLDDHF
                     ATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETLLLNTELPIKEI
                     AESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT          502 a          245 c          188 g          534 t
ORIGIN      
        1 gcaaattatt tacagaaaga acaaaaatgc tctgaaacac tgatttcaaa gcattttttg
       61 ttagtttaaa attactccca ttcttctttt ccaaacgtac aatatatcca aaaccattca
      121 aaatactaga ttctattttt tataatatca ctaaatccac ctaattatag gacgttttca
      181 gatttttagt cccgtcccag tcccagtacc ggagaaatat tgttttaata taatatctct
      241 ttttgtcttc taagctctta aaagcaaaag aacaagtaaa gagtcaagac aaggataaaa
      301 agtccatatt agggcaaata aaaagcttta agacagatga caaatctaag tcaaataaga
      361 aagaccatag caaaggtgca gagagataaa tattggcggt cttcggactg cctttatttt
      421 ttatccattt ttcaaatcaa atttattcag actatatatg cacatataca cttaaattca
      481 tataaaaaca tggcttgtaa aaaattactt taatcacaat aatcgcattt aaaattgtga
      541 tgtttgcaag ctaaattacg gacttcactt ggaagttttc ccttgtatct tttataatag
      601 atagaaaatt tgctggcaga tgaatatcca acagattctg ctatctcttt tataggtagt
      661 tcagtgttta aaagaagagt ttcagctaca ttcattcttt ttctttgagt gtactctgta
      721 atgctttgac aatatttttc cttaaataaa ttttttaatt tagtaccact cattttagat
      781 attttttcaa gcgtgccttg atttacattc gttgcaaaat gatcatctaa gaatcttgct
      841 acatcttcaa gtgctttatc atcatcaatt tcaattttat atttttttct atttaagtat
      901 gtgtcaatta ctatacttat ccattcattt gcctttgctt taaagaaaaa atcagcggca
      961 ggagcgtcca tcttacaatt taatatttcc attgccaccc tttctaaggc ctttgtaagt
     1021 attatttgat tcggttgaag caaggttgaa taaaaagatt ctggattaat gttaatagat
     1081 gctaaatgtt tttctattag ctctttttta aaaccaatgg aaacagcaag ataacaacaa
     1141 ttctcgtgta ataaaaaaac aaaatcatct tttatattat caaaatcaaa agtacataaa
     1201 gagtttgcgg taatagtttg atacggatta aacttttctc cgtttgcact gacaatgtaa
     1261 cttgaataaa ttgaaacata gtctgacata ctataagtgc tattttgaac tacttcctct
     1321 ttaatataaa aatcatgtat atcgataatg aagctgcctc cttcataaaa ccaatatagg
     1381 ccttctgcat aagttgaatt ctcttttttc caacaaaatg tatgacctgc acttgaatac
     1441 ttctcattgt ttttacattc atctacttt
//
LOCUS       DAVLUM010000149         1442 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVLUM010000149 DAVLUM010000000
VERSION     DAVLUM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.149"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..259)
                     /locus_tag="VYN42_002068"
     CDS             complement(<1..259)
                     /locus_tag="VYN42_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEV1463072.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADLGIHESNLIRRS"
     gene            515..1442
                     /locus_tag="VYN42_002069"
                     /pseudo
     CDS             515..1442
                     /locus_tag="VYN42_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          456 a          271 c          276 g          439 t
ORIGIN      
        1 ggctccgacg gattaagttg ctttcgtgaa taccaagatc agccgcaatt tcttcataag
       61 ttcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg cttaatttag
      121 gttttcgccc accttttgcg tgtttaagtt gataagctgt ttttaataca gctaacatct
      181 cttcaaaagt cgtgcgttga acaccaacaa gacgcttaaa tcgtgcatcg gttagttgtt
      241 tacttgcttc ataattcata gaactattat accatatttt gtttcgcagg aagtctattg
      301 aaaaatctcc agactagaga actcacggat agttcctaat ctggagattt cttatttgca
      361 cttttcttgt acaactttag tccacggtaa ataggcctct aaaacctctt tgtttacgag
      421 agtttcctcg tttggaagac attctagaag ataggataga tatttctcgc tatttatact
      481 agactaaaat caaaaagcat tatacaatag tgatatgaaa tcaactaaag aagaaatcca
      541 aaccatcaaa acacttttaa aagactctcg tacagctaaa tatcataaac gccttcaaat
      601 cgttctattt cgtctgatgg gcaaatctta taaagagatt atagagcttt tagactgtaa
      661 tcaaacaacg atttggcgaa atgtaaaaaa atatgaggag ttcggactcg actctctcct
      721 tcaagaaaca cgtggtggtc gtaaccatgc atatatgaca gttgaggaag agaaagcctt
      781 tcttgcccgt catttgaagg ctacagaggc aggagaattt gttacaattg atgccttatt
      841 tcaggcttat aaaaaggagt taggtcgttc ctacacacgt gatgccttct atcaactgtt
      901 gaagcgccat ggttggcgaa atattatgcc acgtccagaa catcctaaga aagcagacgc
      961 tcaaaccatt gtcgcgtcta aaaataaaat ctcaattcaa gaagaaaaga aagcgcttta
     1021 aaaccagtag acgttttcat aaggttcgct tgatgtacca agatgaggct ggcttcggta
     1081 gaatcagtaa actgggatct tgttggtctc caataggagt aggtccacat gtccatagtc
     1141 actatatacg agaatttcac tattgttatg gagctgttga tgcccataca ggcgaatcat
     1201 ttttcttaat agctggtgga tgtaatactg agtggatgaa cgtcttttta gaagagcttt
     1261 cacaagctta tccagatgat tattttttac tcgttatgga caatgctata tggcataaat
     1321 caagtatctt aaagattccg actaatattg gctttgcatt tattcctcca tacacaccag
     1381 agatgaaccc cattgaacaa gtgtggaaag agattcgtaa acgtggattt aagaataaag
     1441 cc
//
LOCUS       DAVLUM010000150         1425 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVLUM010000150 DAVLUM010000000
VERSION     DAVLUM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.150"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..1268)
                     /locus_tag="VYN42_002070"
     CDS             complement(<1..1268)
                     /locus_tag="VYN42_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEV1463073.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASISISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGEGVDSVYHVPIYYELTVINDGSKLTFTYTVTYVNPKTKTLGNISKMGPG
                     YSIYNTGTSTQTMLTLGSGLGKPSGVKNSITDKNGVQVQYYNMSTMTKRGSGYTWGNG
                     AQMNGLFAKRGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFNGGGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASASA"
     gene            complement(1266..1379)
                     /locus_tag="VYN42_002071"
                     /pseudo
     CDS             complement(1266..1379)
                     /locus_tag="VYN42_002071"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
BASE COUNT          387 a          306 c          275 g          457 t
ORIGIN      
        1 cttgctgagg ctgaggcgct tgtcgatgct gaagctgagg cgctttgact agcacttact
       61 gagagtgact tagactgtga aagtgactga ctggtcgtgc tagattcaac tacctttcct
      121 ccaccattga agtagttagt tctaatgtta tctgttttag cagcgtaagg ggtaaatgta
      181 aaggatgtat ccgttccagt aattggtaca gtccaagatg atgttaatcc atatcctcgc
      241 ttagcaaata aaccattcat ttgggcacca tttccccaag tatacccact accccgcttc
      301 gtcattgtag acatattata gtattgaacc tgtacaccat ttttgtcagt aatggagttc
      361 tttacacctg aaggtttacc aagaccactg ccaagggtta acattgtttg tgttgaagta
      421 cctgtattat agatagaata cccaggaccc atctttgata tattaccaag agtctttgtt
      481 ttaggattca catacgtaac cgtataggta aaggtcaatt ttgaaccatc atttatcact
      541 gtcaattcat agtaaattgg aacatgatat accgaatcta caccttcacc tgtataaact
      601 tttgtctcac ttttagcaat gtttagactt gcattaattg caggggcgcc atttacaatc
      661 gtattgccag aaaaaacagc agcttttata gaagccagca attgctcgat ggaatccact
      721 gaacgcttgc gtcgcttagc ataagattgg agattgacat ttgtaactga tgctacataa
      781 tcactagctg gtttcttacg atcttcttcg accttcttag cagttgcttc tgtagcggca
      841 gctgtttgtg atcctaccac agtagatgat gcagagatac ttatcgaagc cgatgtactt
      901 gctgattctg atgcacttgt actcgctgag gtcgaagcgc tggttgaggc tgactcagat
      961 gcagatgtac ttgccgactc tgaagctgac aaactagttg aactcgctga attacttgta
     1021 gatatcgtac ctagaactac tgtatcattt gttgccaaag catccgtttt ctctacagtt
     1081 ttttcaagta ctgccgactc atttgtaaat accttcgttt gagttgcaac ggttccactt
     1141 atgacagttc ccgcagcaac tattcccttg aggatatcaa gcccagtaat tgaatgactt
     1201 actttatctt ctaccgtttc ggtcatgacc tgagtagtat caacaccacc acgcatgacc
     1261 ttaaacaagc caaaaagaga agtcgaggcc cgtagccaat gcttccctga tttgattaat
     1321 ttgaaccgag ttactcggtc tgtttctcta tattcaccct tctgacgtct aaaaaatatt
     1381 ttgaaatttc ctttcgagta ttattttcat gtatggatat aaata
//
LOCUS       DAVLUM010000151         1355 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVLUM010000151 DAVLUM010000000
VERSION     DAVLUM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.151"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            119..1126
                     /locus_tag="VYN42_002072"
     CDS             119..1126
                     /locus_tag="VYN42_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1463074.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            1129..1329
                     /locus_tag="VYN42_002073"
     CDS             1129..1329
                     /locus_tag="VYN42_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1463075.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
BASE COUNT          413 a          268 c          277 g          397 t
ORIGIN      
        1 tcacctttta aaagaaatta ttgggctgaa agtttttagt gattattttt caactttcta
       61 ttgactttta aaaacaaagt gatatcattt agatatcaaa taatgggagg tcattcttat
      121 gactgaaaaa ctaatcaatt caaaaccaaa tggtgtattc gcattgattc tcattgaatt
      181 gacgctcgta cttggtatct ttatatttat aatgggtgtt ggttcggaaa acatttttgg
      241 aattattatc ggacctttac taatcgtaat tgcaggtcta gctcatgctg gtttaaaagt
      301 tgtcaaacct caggaagctc tggttctgac actctttggt aattatacag gtaccatcaa
      361 agaacctggt ttttactttg tcaatccctt cagcgtagca gtcaaccctg caaaccacac
      421 tcgacttgga caaagtggtg atgttagcac aaaatctcct tttttaggtg ctaaatcatc
      481 aaatgacaat gatgtaaatc ttgaaattgg caagaaacac atttccctca aagtcatgac
      541 cttgagcaat tcccgtcaaa aaatcaatga ttgcttagga aaccctgtag aaatcggtat
      601 cgcggtaact tggagagttg tcgataccgc taaggcagtc ttcaacgttg ataactacaa
      661 agaatatctt tcattgcaat gtgatagcgc cctccgtaat attgtccgca tctatcctta
      721 cgatgtgtct cctaatgtgg atactacggg tgacgggcaa gcagatgaag gtagtctccg
      781 tggctctagt gaaattgtag ctaaccgtat tcgtgaagaa atccaaagtc gtgttgagga
      841 tgctggcttg gaaatccttg aagcacgtat cacttaccta gcttatgctc cagaaattgc
      901 tgccgttatg cttcaacgcc aacaagcatc tgccattatt gatgcacgga agatgattgt
      961 agatggtgct gtaggaatgg ttgaaatggc actagaacgg ctcaatgaag gggaattggt
     1021 agaacttgac gaagaacgaa aagctgccat ggtttcaaat ctccttgtcg ttctttgtgg
     1081 caatcatgat gcacaaccaa ttgtcaacac aggaagtctt tactaaagat ggctgaagct
     1141 aaaaaaaagc agatccccct tcgactctca acaaagttat acgctgcact cgcatcatgg
     1201 gcagaagacg actttcgttc agtcaatggg caaatcgaat atctcctcac agagtgtgtc
     1261 aagcaacgga aaaaagacgg aaaatacgta tcagaaacca ttgacgaacc atttgagatt
     1321 gatatttaac accttctcct gtctgccgtg tcgga
//
LOCUS       DAVLUM010000152         1280 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVLUM010000152 DAVLUM010000000
VERSION     DAVLUM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.152"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(667..1239)
                     /locus_tag="VYN42_002074"
     CDS             complement(667..1239)
                     /locus_tag="VYN42_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463076.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGIYLAQLWDKNDAIPNNGRINF"
BASE COUNT          388 a          220 c          210 g          462 t
ORIGIN      
        1 gtgttgttta ttacctttct tgtaataagc ttgttacctg ataagatttt tggaaaaaat
       61 aaaaaaattt ggaaaatagt ttttgcaata ttgacggcag tggcagcatt gtcatttatg
      121 tactaagtta ttttaagaat gtagggaaat aaaccctaca tttttttaag ttttttctgt
      181 tttctaaatt ctatttatcc aagagcttca acatttcttg cttcttcgct tcaagttctg
      241 cacgcttttc ttcgatttcg gcatgttttt tctcgagttc agaacaactt gcatcattgc
      301 taaattcttt tcgccatcag gagatagggt gagtctacat gtctattact cacccaaagc
      361 agtcctacaa agcaggaatt ttctgttact tttttggaaa tagtaacgtt tatacagctt
      421 tgacacttcg tatcaaagcg ccaaacacac tccgagggat ttacagaaag cagaaaagga
      481 atgatctggt ataagatcat tccttttctc tctttttctt taagtaatta tatacaatgt
      541 acgacgaagt cgtcattgca atgctgatcc accacctaaa gggaacttta aacaacattg
      601 ataagataaa gaatataaac aacgaaaata cgttataccc aattaatttt attgtatatc
      661 tcatgattaa aagttaatcc ttccgttgtt aggaatggca tcatttttat cccataattg
      721 tgctaaataa atccccggtg ataataaatt catagcgaat tctaaagcaa catcatttac
      781 aaaccaacta cctagatatc tagaaattgc tgaacgaata gcactttttg ctgcatgttt
      841 tccttttact ttaattagat ttgcaaggcc tgcagtagtt cctcctaatg ctaaagctat
      901 tgcagtatct aatagagcac ccatttgatt aactgtaata ccttgccaag ctgctctaaa
      961 tggagagtat gtaggtggga ttgtataatc gccttgtaat tgtcggttaa ttacttcttt
     1021 gatccattgt tgtgagacgt ctggatgaaa agattggatt tcgtttgcaa gtgtattgat
     1081 ttgttcttct gttagagaag tgacaggttg aagttccata tttgtttcaa tttgtgatac
     1141 ttgttcagaa gcgtatacag ctgaaacact tggaatcgct gatacaatta acacaattga
     1201 cgtcaaaaaa accgaaataa atttcattaa tttgttcatg agcttttctc ctttttattt
     1261 gtatctgctt acattttatc
//
LOCUS       DAVLUM010000153         1249 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.153, whole genome shotgun sequence.
ACCESSION   DAVLUM010000153 DAVLUM010000000
VERSION     DAVLUM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.153"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            219..695
                     /locus_tag="VYN42_002075"
                     /pseudo
     CDS             219..695
                     /locus_tag="VYN42_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            733..1035
                     /locus_tag="VYN42_002076"
     CDS             733..1035
                     /locus_tag="VYN42_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1463077.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            1043..>1249
                     /locus_tag="VYN42_002077"
     CDS             1043..>1249
                     /locus_tag="VYN42_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1463078.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYE"
BASE COUNT          426 a          214 c          238 g          371 t
ORIGIN      
        1 aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtattag aacagaaaaa
       61 tgcttggagt atttgtttgt gtgtttattt ttatataaca aactataaac aaaacaaaaa
      121 tataaaaaag agacaaaaaa gaacagaaag taattaacaa cgatttcata tagtgttata
      181 cttatagcat aaagttaatg gaaagaaggg aaaaccttat ggtattagat tatttctttg
      241 acaaaaacct tgtgttttgc ttagaagcgg ataatcaaga ataactcttt gatcaggtag
      301 caagcttgtt ggaggaacga gaaattgtaa ctccaactta tcgtgaagcc ttgatcacgc
      361 gtgaaaagtc atttccaact ggtttagata tggaatttct aggaaaggac ttgccaaatg
      421 tagcgattcc tcacacagat attgttcata atttggctga aaaagttgtg gtcgttcgat
      481 tagagaaacc ggtgactttc cataatatga ttgcgccaga taaggaagta gaagtatcct
      541 tgctcttctt tatcattaat aattcaagtt caagtcaaac gaacattctt gctcagttaa
      601 tggacttctt cacaggaaat ggtcatcttg aagacctatc aaaaatttct gaaccagaag
      661 ccctttatgc ttacattgct gaagcaaccg cttaatcttg tctattaaaa aataaaatcg
      721 gaggaaatcc aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac
      781 caaattaaaa gtgctctaga agaagaactt tcaaaccgtg gttacgatgt tcactgtgat
      841 gcagttatgg tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca
      901 atcgctgcaa cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc
      961 ttattccgta tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa
     1021 caaaacatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa ctgatgcacg
     1081 atttaagcgt cttgttggtg ttcagcgcac gacttttgaa gagatgttag ctgtattaaa
     1141 aacagcttat caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga
     1201 ccttcttatg gccactcttc aatatgtgcg agaatatcga acttatgaa
//
LOCUS       DAVLUM010000154         1203 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.154, whole genome shotgun sequence.
ACCESSION   DAVLUM010000154 DAVLUM010000000
VERSION     DAVLUM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.154"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            521..691
                     /locus_tag="VYN42_002078"
     CDS             521..691
                     /locus_tag="VYN42_002078"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1463079.1"
                     /translation="MTKQIPKFTKDTAQLYTCKWLLYNKVTKMYDHTIVNHSVREYIT
                     DSISTNTIEEAE"
BASE COUNT          457 a          211 c          177 g          358 t
ORIGIN      
        1 aaagagcaaa ctaggaagct agctgcaggc tgctcaaaac actgttttga ggttgtagat
       61 agaactgacg aagtcagtaa catctatacg gtaaggcgac gctgatgtgg tttgaagaga
      121 ttttcgaaaa gtattagtta aatcttgttt aatatctcta caccatacta ttttacatat
      181 attatttagc gccacatagt actgaactct ctccaaaaac ggttatgcct ctttgaatag
      241 ggcgttatca caagaaaagc atctccacgt ttcaacttca tatggctcaa aaacaatcaa
      301 ttgatgctaa aacctgtacc tagatgtttc ggttcataaa accataaaac tgtaaaagtg
      361 gatgaaattg atagcgatag tcaaatcaag aggcatcata actctaaaaa gtcacaatat
      421 ataagttcat cctcggaaaa atatcattct aattgttgaa atgcctacat gaaaagaaac
      481 gtcaaatgct catgaaacaa cgaatacagg tatcaaaact atgacaaaac aaatccctaa
      541 atttactaaa gacactgctc aactttacac ctgtaaatgg ttgttgtata ataaagttac
      601 aaagatgtac gaccacacta ttgtaaatca tagtgttcgc gaatatatta ctgatagcat
      661 ttctacaaat acaattgaag aggctgaata ggctttaaac gaaatatgtc agtgttttgg
      721 cattcctagc cttcatatca tttaaagaat tgtatagata aaattttttc caatacagac
      781 actcgtaaca actgcttcat ttttctacca acatatttag gaacaggata agatacaaga
      841 ggattaatcc atagctcagt tctataccaa tctaagacaa ataagctaaa aaaacgattg
      901 ataataagca aatagattcc aaattttctc tatctgctca ttttaataaa caatactagt
      961 gtaactatcc ttccagtcag aagcttgtca aatcacaccg aaaattcttc taaaatttat
     1021 ctcgttaggc aatcaagcaa aaactcgacg atagtacaaa cattatcata cagaattgac
     1081 ttcctaaatt atatacttta gtaaggtttt cggataagaa aaaaggttca ttttacattt
     1141 ctaaacattc ttttctaaga tgaaaaacag aatttttcga ttgtaattta aagcaacaag
     1201 aag
//
LOCUS       DAVLUM010000155         1178 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.155, whole genome shotgun sequence.
ACCESSION   DAVLUM010000155 DAVLUM010000000
VERSION     DAVLUM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1178
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.155"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..1163)
                     /locus_tag="VYN42_002079"
     CDS             complement(<1..1163)
                     /locus_tag="VYN42_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEV1463080.1"
                     /translation="MELSEMINNVFESCIHPEYHFIDLSKIKENRIAIIGGNKSEYLN
                     LILNLMLQGKVVIPINPIQTNSQIETLLNLSDVEAVLTDNSFQCKSEKKTYLFCEFKH
                     IYNNHEREISDTPLVFFSSGTTGVPKPVMINKLAFTELINLMIAQLEISSDDVLYLPS
                     HIAFIQSLWAAMIVIFSGGRVIFKDRITYKTFFKELQLNDATITVMVPTTMNKLVNLY
                     TNTLQGCKKLRCIIVGGEIINKDSANFLLNKLKNTNIANAYGMVETTAVCCLQYGRDL
                     KNINSVGTTLPGVEVEVKNIDDDGNGDIWIKTNRFMSGYYPSKYTGEWLYTGDRGYKN
                     KEGLLFVTGRESLSINKGGIKINPIEIEQIILQLPDIQLCKVEKISDNIYGEN"
BASE COUNT          382 a          220 c          137 g          439 t
ORIGIN      
        1 taattttctc cgtaaatatt atcactaatt ttttcaactt tacaaagttg aatatctggc
       61 aattgaagaa taatctgttc aatttcaata ggattaattt ttatacctcc cttattaatt
      121 gacaaacttt cacggcctgt tacaaataaa agtccttcct tatttttata tcctctatct
      181 cctgtatata accattcacc agtgtattta ctcgggtaat atccgctcat aaagcgattt
      241 gtctttatcc agatatcgcc attaccatca tcatctatat tctttacttc aacttcaacc
      301 cccggtagag ttgtaccaac agagttaata ttttttaaat cacgtccata ttgtagacaa
      361 caaactgcgg ttgtctctac cataccatat gcatttgcta tgtttgtgtt tttcaattta
      421 tttaataaaa agtttgcact atccttattt ataatctctc cacctacaat aatacatctt
      481 aattttttac acccttggag agtatttgta tataaattaa caagtttatt catcgtagta
      541 ggtaccataa ccgttattgt tgcatcgttt agttgaagtt ccttaaaaaa tgttttatat
      601 gtaatcctat ctttaaaaat tactcttccc cccgaaaaaa ttactatcat cgcagcccag
      661 agagattgaa tgaaagcaat gtgggagggg agatacaaca catcatcact agatatttct
      721 aactgtgcta tcatcagatt aattaattct gtaaaagcta atttattaat cattaccggc
      781 ttaggcactc ctgttgtacc tgatgaaaaa aacactaaag gagtgtccga aatctctctt
      841 tcatgattat tataaatatg tttaaattca caaaatagat acgttttttt ctcactttta
      901 cattgaaagc tattatctgt taatactgct tcaacatcag acaaattcaa aagtgtttct
      961 atttgagaat tagtttggat cggattaata gggataacaa ccttaccttg tagcataaga
     1021 tttaagatta aatttaaata ctcagattta tttcctccta taattgctat cctattctct
     1081 tttatctttg ataaatcaat aaaatgatat tcaggatgta tacaactttc aaacacatta
     1141 ttaatcattt ccgacaattc catatctcac ctaaactt
//
LOCUS       DAVLUM010000156         1162 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.156, whole genome shotgun sequence.
ACCESSION   DAVLUM010000156 DAVLUM010000000
VERSION     DAVLUM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.156"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..212)
                     /locus_tag="VYN42_002080"
     CDS             complement(<1..212)
                     /locus_tag="VYN42_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV1463081.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEI"
     gene            complement(225..974)
                     /locus_tag="VYN42_002081"
     CDS             complement(225..974)
                     /locus_tag="VYN42_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1463082.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVAHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          409 a          220 c          123 g          410 t
ORIGIN      
        1 ttaatttcag aaaatgtatc aaaaaaagta atatttaagt tattctcgca aaaaaacttc
       61 ataagctctt catttttaga tggaagaatg ccctttttta aattatttat ttttacagaa
      121 tctatatcat atgcaacaac tttatattta gatgcaaata gtaacgcgta ggccagccca
      181 acatgcccca aaccaattac tgctatattc ataaaactac ttccttattt cttaatccaa
      241 aatctaatag aataagctgc cccattcctt aaatacaact ctttaatatt gtttaaaagt
      301 ttttcaactg atttccagat tatcaaaatc tgagatttat agcacaatat tgatgatatt
      361 ctatcaatat aatgtttttc atcaagttcc tcttgataca tttttaattc tttagttttt
      421 cccatataac taaccatact actatcactt acatatggga agtcctcata atatattact
      481 ttataacgca taaattcaag cgcccttcca atactattca caaaaacatg agcaacatgg
      541 tcaccaagtg aaagcggaca atatacgaca catttgtcgt ctaaatgcat taacagctct
      601 tttatgatat cattctttaa tgtgtcctca ttttttaatt cactatagat atgacggtat
      661 agaaaattgc catttctatc tttcctatag agacattcat agtacgataa gtgtctaaaa
      721 tcacattgta gacgttcaca agctaacctg tcttctttct tcctttcttc aatcggatat
      781 ttcccaaggt tacacaactt atgaaattgc ttagcagagg gctgtagctg ttggctcaaa
      841 gggtaaccag aaaatatagt aataacaagt acaatttctc cttctgaagt taattttgaa
      901 atataatcac cacaggaaaa aattgcgtca tctaaatgtg gagataaaaa gatatactta
      961 gtattgttac tcataaccat tccctctaca atttatctaa aaactcacta agtgtctgat
     1021 taaattccac atcatcaaaa aaattcacct tattcttaat aatgaatatt tcgttaaata
     1081 aacatatata taaatatttc aatatccttt caatatcatc ctctaaattc tcctcaatat
     1141 tttgtatcag cccatttaca at
//
LOCUS       DAVLUM010000157         1152 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.157, whole genome shotgun sequence.
ACCESSION   DAVLUM010000157 DAVLUM010000000
VERSION     DAVLUM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.157"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            84..491
                     /locus_tag="VYN42_002082"
     CDS             84..491
                     /locus_tag="VYN42_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1463083.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VYN42_002083"
     CDS             656..955
                     /locus_tag="VYN42_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1463084.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          412 a          227 c          196 g          317 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaatcacg taagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgttataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct at
//
LOCUS       DAVLUM010000158         1121 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.158, whole genome shotgun sequence.
ACCESSION   DAVLUM010000158 DAVLUM010000000
VERSION     DAVLUM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.158"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            23..307
                     /locus_tag="VYN42_002084"
     CDS             23..307
                     /locus_tag="VYN42_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463085.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            300..538
                     /locus_tag="VYN42_002085"
                     /pseudo
     CDS             300..538
                     /locus_tag="VYN42_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            634..852
                     /locus_tag="VYN42_002086"
     CDS             634..852
                     /locus_tag="VYN42_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463086.1"
                     /translation="MMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT          412 a          176 c          185 g          348 t
ORIGIN      
        1 taaattccat aggaggaaga caatggattg gtacgattat atgatacagg catccaaaca
       61 atcacaattc aacgcaagcc attggtttcg ctatttgcga aaagttattt ttgaagacta
      121 ttcttattta acaaaccaag atgtagaaaa gttgctagac tccaaagaac taacccgttt
      181 tcaaaaaatt agcttgaagt atgcctttca agagcatact ccaactcata aatatgtgat
      241 ttcattaaat aaacctgcta agttaaccaa tgttcaaaaa ttgatggaga aatacaaaca
      301 tggataaaat gaaaccggtc ttccaagccc taaataagaa attaattcag gaaaatctga
      361 ctttaacaat tatggttatg tcttagaata tcatggttta cgtgccacac aagatgttga
      421 tgctttttat gaccaaaatc agaaaatcaa tgaaattatt gctcgtgtag gaaaacagtt
      481 taatcttaac atccacgaag agttatggct caacaatcat gttgcaaagc aaatatgaac
      541 aaacaacctc ccttaagttt atgcgaatcc ttgtactcat ttgagaatct gaccgtttta
      601 gtagtcccta ttgagtatgt gttaggaatg aagatgatga gtatcagaga gcaggatttg
      661 aaagatattg gtgcaattat taaatacaaa aactttcatt caccattcga tacctttaaa
      721 tatttaaaag atatgggatt tgatactatt gacctctctg ttctattaga aggttttagt
      781 tatgcttatg gtatggattg gttagaaaaa ttttttaaag aaaatcaaga taaacttcgc
      841 gaattttatt aacagtatca aacaagatga ttgtcaatta gccagtcgtc ttgtttttat
      901 gatggaatga aataaaatcg gaacaaatca cttagagaat tccagacaat ttctagcact
      961 gtttgagacg tttcagcgga ctatagcaaa atgaaataag aataagacaa atcgatcagg
     1021 acagtcaaat cgatttctaa gaatgtttta gaagtaaagg tgtactattc taatttcaat
     1081 ctactatatt tcagattcgg tccactattc cttcccaaaa a
//
LOCUS       DAVLUM010000159         1117 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.159, whole genome shotgun sequence.
ACCESSION   DAVLUM010000159 DAVLUM010000000
VERSION     DAVLUM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.159"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            24..>1117
                     /locus_tag="VYN42_002087"
     CDS             24..>1117
                     /locus_tag="VYN42_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEV1463087.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKT"
BASE COUNT          383 a          156 c          210 g          368 t
ORIGIN      
        1 accattatta aggggtcata cttgtgaatc agagtaatga aatattttta aatacaatac
       61 aggaaaaaac acactataag aggtctatct cttcatcatt tcaggaatta aaaaaatgga
      121 attctttgat atttaggaga gggcgatatt ggtaccaatt tgataattgg agtataccca
      181 atactggtgt aataaaggaa tggtatgtcg aagataatga ctggattcct aaggttagtt
      241 cttccagttt agacaattca aattcactta aaattgtctt tgatgtggaa aaatatactt
      301 tgccagatga tagtatctta caggatgtta ggatttcatc tgatgagagt tatatagttt
      361 tggttgtatc ctcactgcgt agcactaatt taattggaat aaaaaaatat actatggaag
      421 agttatttat cattgaagat atttcagtag aaagttcgtt ctatttgggt aaattcggtg
      481 ttatgtatac tcgctccaaa gagtacggga ggccaagtaa gttattctat aaatcttttg
      541 atagctttac agaagaggaa ctgtttgaag aaaacgaatg ctcttttcga ttaaaaatag
      601 tccacattga tagcaataat tgttttgtaa agtcagtaga ctttcagaaa ggcaggattt
      661 ttctatacag tttcgaccgg acgggttttg ttagacactc ttacacagaa acggtagccc
      721 caacacctag agatatcgct ctatttagta cagaaaaagc acagtacttt cttgggctct
      781 cttcaactga agaaaagaaa gatcaactaa ttctaaggga aacttcttcg ggagacagag
      841 tttctattac tataccatat caagataggg ctagaagagt tcactgtata ggacgttata
      901 tccttttaga ctgttcaaac gcagcgaatt ccgtctttta tcttgctaca tttaaaaata
      961 atagtttgag ggagttgagt gttaataaga taacatttga tgaaaagaca acactttatg
     1021 aaaattcatt ttctgatcgt gttcttctgt ttttagagag gagaactttt tacgaaaaaa
     1081 tacttagttt tgatttaata gaaaatacat taaaaac
//
LOCUS       DAVLUM010000160         1062 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.160, whole genome shotgun sequence.
ACCESSION   DAVLUM010000160 DAVLUM010000000
VERSION     DAVLUM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.160"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            121..>1062
                     /locus_tag="VYN42_002088"
     CDS             121..>1062
                     /locus_tag="VYN42_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV1463088.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFL"
BASE COUNT          380 a          190 c          218 g          274 t
ORIGIN      
        1 gtttagctga aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta
       61 taagaaaaca cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag
      121 atgcaagaac attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt
      181 gagcggtgga agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaaaggcg
      241 cctcaaacga ttcataatga agtcaaaaga ggtacaactt tacaacaagt gagaaaaggg
      301 ctatacaaaa aggtctattc tgccgattac gcacaaactg tttaccaatt caatcgaaaa
      361 cggtcggtga aaaagttaat tttaacaaag gaaatcagag agaagatctt acactatcat
      421 aagcaaaaat tttcgcctga aatgatggtt aacaagaagc aagtgaaagt tggtatttca
      481 accatctact actggtttca taatggtcat ttaggattga cgaaggccga catgctttat
      541 cccagaaaaa ggaaaggtgt caagaagcaa gctagtccga actttaagcc ggcaggtaaa
      601 tctatcgaag aacgtcctga cgttattaat cttcgcttgg aaaatggtca ttatgaaatt
      661 gataccgtcc tactgactaa gataaaaaat tattgcctgt tagtcttaac cgaccggcgg
      721 agcagacacc aaattataag gttaattcca aataaaactg ctgaatctgt caatcaggcg
      781 cttacgttac tattagggga gcatcgtatt ctgtccatta ctgcagataa tggttcggag
      841 ttcaaacgat tgtctgaggt atttcctgag gaacatatct actacgcaca tgcttactct
      901 tcatgggaga gaggttcaaa tgaaaatcat aatcgattaa ttcggagatg gttacctaaa
      961 ggaaccaaga aaacgactcc gaaagaagta gcttttatcg aaaattggat taacaactac
     1021 cctaaaaaat gcttggacta caagtcgcca agtgaatttc tt
//
LOCUS       DAVLUM010000161         1047 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.161, whole genome shotgun sequence.
ACCESSION   DAVLUM010000161 DAVLUM010000000
VERSION     DAVLUM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.161"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(15..866)
                     /locus_tag="VYN42_002089"
     CDS             complement(15..866)
                     /locus_tag="VYN42_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1463089.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYIWNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLSEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKVFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVEILEKE
                     INDFSNL"
BASE COUNT          331 a          147 c          181 g          388 t
ORIGIN      
        1 agagttatta caaattatag gtttgaaaaa tcattaattt ctttttcgag tatttcaact
       61 aatgcctctt ctttggttag tcgtaataaa gttattcctt tatcaatcaa atcggagtta
      121 tgttgtagta ttcccaagcg tacttgagag aatccaagaa tatcgtatat ttttaattct
      181 tctgctaata ccaaaagttg tagggtgatt gtttcacatt ctttgaataa atgatgttga
      241 aaatatacag tggagagatt ggctaaaaaa gatgataaaa atacttttgt ttctcggaag
      301 tatttatatt tctcgatggt tttcataatt ctatcaataa gaaggggaag attttcagaa
      361 ggaaagaaaa agagaatggt tccaagcaat ttcaaatcac taatgtacca tgtatccata
      421 ggttcaagat agtcccaaat ttcttcagac aaatctttca agacgtggtt gtttttgaat
      481 cctttagttc gtaactctgt gacaattttt gtatgacgat agatattttg aataggaaca
      541 tcgtgatgtg tcttaagata tttttgacat ttctcagtga gttcaaccat ttttctagta
      601 tcttgaaaag tagacggatt ttggctctct acaataatat ctcgcctttt actaggatgg
      661 tattcgttcc atatatactt gaattctgcc aagctcatat caatttgttc aagaagaaat
      721 accatgtttt caaaactggg aataacttta ccgtgttcaa tatttgttag agttgtccga
      781 tgtatgactt gtccacatac atcttgttgg gtcaatcctt ttgactttcg aatttcttta
      841 aaaatctgtc cataatccca tctcatattg ttcctcctag gtaaatgtga atattttcta
      901 catttataaa aaacgtagaa aaaggtggta ttattatatc aaaaaggagg gaaaagtcat
      961 ggaaatagaa gattcactta attttgttat atattgtaat gattgggagc ctttaatacc
     1021 atggtttgat atatggtttt gggagtg
//
LOCUS       DAVLUM010000162         1047 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.162, whole genome shotgun sequence.
ACCESSION   DAVLUM010000162 DAVLUM010000000
VERSION     DAVLUM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.162"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..675
                     /locus_tag="VYN42_002090"
     CDS             <1..675
                     /locus_tag="VYN42_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HEV1463090.1"
                     /translation="SKDILGMINSLNIDPSYVKFLSKFHKRNFTIYDLLNYCRVHKLF
                     ELIDELCQMQKYIEYIQHRITFQINLFDFRGSEIFEGIYYKCVDKYERPFLDAGTYSN
                     LIFEVTKKNILSGGLAVCIEAILDRIHISQKPKKVFVKYVGGENFKIDDFYNILTLIR
                     KEKLKNHFVKEEVSSLAIAKAKRRAYIQKYDLFIAIGEREKNSHEFMIEELKTGLRRI
                     LILNGG"
     gene            665..>1047
                     /locus_tag="VYN42_002091"
     CDS             665..>1047
                     /locus_tag="VYN42_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463091.1"
                     /translation="MEDNQVRRKLYYGISSAAGWSWGVSFLVTYTLIHEKGVIPFAVW
                     AFFNSLAIPIFGVLFKKLSRLKEIMVNNLWLVYFMAIVQCFSIIINLQAMFQMGTLIG
                     LSSSMSTLISLFAGGIFIISVIKNG"
BASE COUNT          370 a          112 c          191 g          374 t
ORIGIN      
        1 agtaaagaca tattaggtat gataaattca ttaaatattg atccaagtta tgtaaaattt
       61 ttatcgaaat ttcataagag gaattttaca atatatgatt tattaaacta ttgtagggtt
      121 cataaactat tcgaactaat tgatgaactt tgtcaaatgc agaaatatat agagtatata
      181 caacatcgca ttacttttca aattaatttg ttcgacttta gaggatctga aatttttgaa
      241 ggtatttatt ataaatgtgt agataaatat gagagaccat ttttagatgc tggaacttac
      301 tctaatttaa tatttgaagt aactaaaaag aacattctca gtggtggttt ggcggtctgt
      361 atagaagcta ttttagatag aattcatatt tcacaaaaac ctaaaaaagt ttttgtgaaa
      421 tatgttggtg gagagaattt caaaatcgat gatttttata atattttgac tctcatccga
      481 aaggaaaaat taaaaaatca ttttgttaaa gaagaagtta gttcgttggc tatagctaaa
      541 gctaagagga gggcctacat tcagaaatac gatttattta tagctattgg tgaaagggaa
      601 aaaaacagtc atgaatttat gattgaagaa ttaaaaacag gattaagaag aatattaata
      661 ttaaatggag gataatcaag tgcgaaggaa attatattac ggaatcagtt cagcggctgg
      721 atggtcttgg ggagtttctt ttttagtgac gtatacatta attcatgaaa aaggggtaat
      781 cccttttgca gtgtgggctt ttttcaattc tttagctatt ccaatttttg gggtactttt
      841 taaaaaatta tcaagactaa aggaaattat ggtaaataat ctctggttag tatactttat
      901 ggctatagtt caatgctttt cgattattat taatttacag gcaatgttcc aaatgggaac
      961 tttaattggt ctctcttcaa gtatgtcaac gttaatttct ttatttgctg gggggatatt
     1021 cataataagt gtcatcaaga atggcta
//
LOCUS       DAVLUM010000163         1040 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.163, whole genome shotgun sequence.
ACCESSION   DAVLUM010000163 DAVLUM010000000
VERSION     DAVLUM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.163"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..>1040)
                     /locus_tag="VYN42_002092"
     CDS             complement(<1..>1040)
                     /locus_tag="VYN42_002092"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463092.1"
                     /translation="LAETDALVLAEAEALVDAEADALVDAEADALVLAETDALVDAEA
                     DALVDAEAEALVLAEAEALVLAEADALVDAEAEALVDAEADALVDAEADALVDAEAEA
                     LVDAEAEALVDADSDAEVLAEAEALVDAEAEALVDADAEALVLAEAEALVDADSEADV
                     LAEADALVDAEAEALVDAEAEALVDAEADALVDAEAEALVDAEADALVDAEAEALVDA
                     EAEALVDAEAEALVDADSEAEVLAEAEALVDAEAEALVDADAEALVLAEADALVDAEA
                     EALVLAEADALVLVDADVLAEAEALVEAEAEALVDADSEALVDAEAEALVDADSEALV
                     EAEVEALVLAEA"
BASE COUNT          247 a          349 c          230 g          214 t
ORIGIN      
        1 tcagcctcag caagcacaag cgcctcgact tcagcctcaa cgagtgcctc tgaatctgca
       61 tcaaccagtg cttcagcttc agcgtcaaca agtgcctctg aatctgcatc aaccagtgct
      121 tcagcttcag cctcaaccag cgcctcggcc tcagcaagta catcggcatc aacaagcacc
      181 agtgcgtcgg cttcagcaag tactagcgcc tcagcctcag catcaaccag tgcatcagcc
      241 tcagcaagta ctagcgcctc agcatcagcg tcaacaagtg cttcggcttc agcatcaaca
      301 agtgcctcgg cctcagcaag cacctcagct tctgaatcgg catcaacgag tgcttcggct
      361 tccgcatcaa caagtgcttc ggcttccgca tcaacaagtg cttcagcttc agcatcaaca
      421 agtgcgtcag cttccgcatc aacgagtgct tcggcttccg catcaacgag tgcgtcggct
      481 tcagcgtcaa cgagtgcttc ggcttcagca tcaacgagtg cttcggcttc agcgtcaaca
      541 agtgcgtcag cttcagcaag cacatcagct tctgaatctg catcaaccag tgcttcagcc
      601 tcagcaagta ctagcgcctc agcatcagcg tcaacaagtg cttcggcttc cgcatcaaca
      661 agtgcctcgg cctcagcaag cacctcagcg tctgaatcgg catcaacgag tgcttcggct
      721 tccgcatcaa caagtgcttc agcttcagca tcaacaagtg cgtcagcttc cgcatcaacg
      781 agtgcgtcgg cttccgcatc aacgagtgct tcggcttcag cgtcaaccag tgcgtcagcc
      841 tcagcaagca caagcgcctc agcttcagca agtaccagtg cttcagcttc cgcatcaacg
      901 agtgcgtcgg cttcagcgtc aaccagtgca tcagtctcag caagcaccag tgcgtcggct
      961 tccgcatcaa ccagtgcatc agcctcagca tcgacaagcg cttcagcttc agcaagtacc
     1021 agcgcatcag tctcagcaag
//
LOCUS       DAVLUM010000164          969 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.164, whole genome shotgun sequence.
ACCESSION   DAVLUM010000164 DAVLUM010000000
VERSION     DAVLUM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.164"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            85..801
                     /locus_tag="VYN42_002093"
     CDS             85..801
                     /locus_tag="VYN42_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1463093.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
BASE COUNT          340 a          190 c          152 g          287 t
ORIGIN      
        1 attctaattt tttattcaaa agactactat tttttcgctt ttatggtaaa attttctata
       61 gagaaggaaa atagaggtaa aaatatggca attcccaaat atcaatacat aaaagacgaa
      121 ttaaaaaata aaatcatctc tgggcagttt agcagtggag ataaatttta cactgaagca
      181 gaactcattt caatgtacga tgtcagctct atcacagttg ttcgcgcctt aaacgacctt
      241 gccaaagatg gctatattgt ccgccaacaa ggaaaaggaa ccttcgtttc acgtgcgcgc
      301 aaacacaagc ttgtagagtt ttcagatatt gaactcttca atgctaaaga tgataaggta
      361 actgttcttt caattgaacg cggaaacaag cttgtttact tggaaaaatt gggtctacgc
      421 ggcgatcaat tctactacaa gattgaacgt atccgcgaat caaacggtgt cgtttatatc
      481 taccatacat cctacatccc agaacaatat atcaacgcaa attatccaaa ccttgaatac
      541 tatagttcta tctataatcg tttcaagtta gactaccaca ttcacatgaa tgatgaacac
      601 tttgaagaaa tcaacgaaat agtctttcca actccagaac atgcggcttc agtcctcgga
      661 gtcgatgaac aattccctac tgtcctacaa actaaaatca ccaaactcga atcaactggc
      721 caagttttag aatacagtga aacttacaaa cgatctgatt actacaagat taaatttatc
      781 tcatgtgacc gtgatcacta agaagaaagc ctgagcctaa tcgctcgggc tttttctatg
      841 cttattatac cacaccaaaa aggtagcgct tacctatttt tggaagattc tataatttgt
      901 ggaatatttt atagaaatag aaccaaaaat tatactagat atatatatgt atttttcgac
      961 caatctgaa
//
LOCUS       DAVLUM010000165          881 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.165, whole genome shotgun sequence.
ACCESSION   DAVLUM010000165 DAVLUM010000000
VERSION     DAVLUM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.165"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(8..81)
                     /locus_tag="VYN42_002094"
     tRNA            complement(8..81)
                     /locus_tag="VYN42_002094"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="VYN42_002095"
     tRNA            complement(95..168)
                     /locus_tag="VYN42_002095"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="VYN42_002096"
     tRNA            complement(174..247)
                     /locus_tag="VYN42_002096"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="VYN42_002097"
     tRNA            complement(263..336)
                     /locus_tag="VYN42_002097"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="VYN42_002098"
     tRNA            complement(346..431)
                     /locus_tag="VYN42_002098"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="VYN42_002099"
     tRNA            complement(439..510)
                     /locus_tag="VYN42_002099"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="VYN42_002100"
     tRNA            complement(533..605)
                     /locus_tag="VYN42_002100"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="VYN42_002101"
     tRNA            complement(624..705)
                     /locus_tag="VYN42_002101"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
     gene            complement(711..783)
                     /locus_tag="VYN42_002102"
     tRNA            complement(711..783)
                     /locus_tag="VYN42_002102"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(748..750),aa:Lys,seq:ttt)
     gene            complement(808..880)
                     /locus_tag="VYN42_002103"
     tRNA            complement(808..880)
                     /locus_tag="VYN42_002103"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Asp,seq:gtc)
BASE COUNT          232 a          256 c          199 g          194 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      781 gtctaaaata acttgcgtta tcttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      841 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc t
//
LOCUS       DAVLUM010000166          877 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.166, whole genome shotgun sequence.
ACCESSION   DAVLUM010000166 DAVLUM010000000
VERSION     DAVLUM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.166"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..>877
                     /locus_tag="VYN42_002104"
     CDS             <1..>877
                     /locus_tag="VYN42_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV1463094.1"
                     /translation="LFQLLTGYGTDYACKELSADVYFPKLLEGGQLASQPTLSRFLSR
                     TDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGY
                     HPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYD
                     LIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDENLTILPHSAYSETLYQAGSWSHKRR
                     VCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTD
                     SSTLIKNEVRMMMSCI"
BASE COUNT          246 a          199 c          176 g          256 t
ORIGIN      
        1 cctctttcaa ctgttaacag gctatggaac ggactatgct tgtaaagaat tgtcagctga
       61 tgtctacttt ccaaaattgt tggaaggagg gcagcttgct tcacagccaa ccttatcccg
      121 ttttctttcc agaactgacg aggaaacagt ccatagtttg cgatgcctca accttgaatt
      181 ggtcgaattc tttttacagt ttcaccagct aaaccaactc attgtagata tcgattctac
      241 ccatttcaca acttatggca agcaagaagg tgttgcttat aacgcccact atcgtgctca
      301 tggctatcat cctctttatg ctttcgaggg gaagacaggt tattgtttca atgcccagct
      361 tcgtcctggt aatcgttatt gttctgaaga ggcagacagc tttatcacac ctgttttaga
      421 acggtttaat caacttctct ttcgaatgga tagtggcttt gcgaccccaa aattatacga
      481 tttaattgaa aaaacagggc aatactacct cataaaactc aagaaaaata ctgttctgag
      541 ccgtcttgga gacctttccc tcccttgccc acaggatgag aacttaacca tcttgcccca
      601 ctccgcctac tcagaaactc tctatcaagc aggatcttgg tcgcacaagc gtcgtgtctg
      661 ccagttctct gaacgaaaag aaggaaactt gttctacgat gttatttctc tcgttacaaa
      721 tatgacgagt ggaacaagcc aagaccagtt tcagctttat cgtggacgtg gtcaagccga
      781 gaatttcatc aaggagatga aggagggatt ttttggcgat aaaacggata gttcaacctt
      841 aatcaaaaac gaagttcgta tgatgatgag ctgtatc
//
LOCUS       DAVLUM010000167          815 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.167, whole genome shotgun sequence.
ACCESSION   DAVLUM010000167 DAVLUM010000000
VERSION     DAVLUM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.167"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..809
                     /locus_tag="VYN42_002105"
     CDS             <1..809
                     /locus_tag="VYN42_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEV1463095.1"
                     /translation="YFSKVIWTKKDSYDVSIPISLFWKSEDTDELPRRKKCILSVYGA
                     YGKNDNSDLDEIMLSIIDAGFIYAIVHVRGGGYLGGEWYRSGKALNKWNSIRDFIEGV
                     NYLRENDVIDSKRLGLITSSAGGIIAGAVLNEEKNLLQSILLFSPFINPYDTLQNPND
                     PLSKTEIAEWGDIRDPEVKAYIKSYSPMQNIEKARDSNTVIVNILGEKDPYINNNEVI
                     EWSKKLNSIGVKSLLYLNKAAGHGGFTPSDVLLMIDTLNYFFEEVGRNNL"
BASE COUNT          283 a           90 c          175 g          267 t
ORIGIN      
        1 aatatttttc taaggtgatt tggactaaaa aagacagtta tgatgtaagc ataccgattt
       61 ctttattttg gaaaagtgaa gatacggatg agctcccaag aagaaaaaaa tgtattctaa
      121 gtgtctatgg ggcttatggt aagaatgata attctgattt agatgaaatt atgttatcta
      181 taatagatgc aggttttatt tatgctatag ttcatgtaag aggtggaggc tatttgggtg
      241 gtgaatggta tcgctcagga aaggcgttaa acaaatggaa ttctatcaga gattttattg
      301 agggagtaaa ttatttaagg gaaaatgatg taattgacag taagcgatta ggtttaataa
      361 cttctagtgc aggtggaata attgctggtg cggtgttgaa cgaggaaaaa aatttattgc
      421 aaagcattct cttattttcg ccatttataa atccttatga tacacttcag aatccaaatg
      481 atcctctttc taagaccgaa atagcagagt ggggagatat tagagaccct gaagtaaagg
      541 cttatataaa gtcatattcg cctatgcaaa atattgaaaa ggcacgagac tcaaatactg
      601 ttatagttaa tattttgggt gagaaagacc catatattaa taataacgaa gtgatagagt
      661 ggtcaaagaa attaaattct attggagtta aaagtttgtt gtatttaaac aaagcagctg
      721 gtcatggagg ttttactcca tcagatgttc tcttaatgat tgatacttta aattatttct
      781 ttgaagaagt gggaaggaat aacttatgaa ttatt
//
LOCUS       DAVLUM010000168          769 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.168, whole genome shotgun sequence.
ACCESSION   DAVLUM010000168 DAVLUM010000000
VERSION     DAVLUM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.168"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..>769)
                     /locus_tag="VYN42_002106"
     CDS             complement(<1..>769)
                     /locus_tag="VYN42_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV1463096.1"
                     /translation="LSRTKNELSGVKSAQATYEETTTRRLSELTNLANGKASKSELTQ
                     TAEELASRIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDY
                     VRISFDVTFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSED
                     YQTNNVFIRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQ
                     RADSLDAGVSRLTEGLRTKADISSLNVTAENIRQSVKR"
BASE COUNT          212 a          186 c          161 g          210 t
ORIGIN      
        1 cctcttcaca gattgccgga tattttcagc agtcacattg agtgagctga tatcggcttt
       61 agttctaagg ccttcagtca gacggcttac accagcgtcg agtgaatcag cacgctgctt
      121 aaagttggat tcgactactg agacacggtc ttcttggtct tcatacgctg gttgataggc
      181 tggaaaataa ttaccaaccg ataacatagc gttctcaatg acgacctgca gaccagcagg
      241 aaatccataa ttagtaccaa aacgaatgaa cacattatta gtctgatagt cctcagaaga
      301 actagacaag tcaatcgtaa actcaaaatg ttggcgttcg acagttccac ctttaaaaat
      361 taagtttctg taggcatacc atggatgagc actaaaatgc accatagcag gcatgtcatt
      421 tactagggcg acagggaaag tcacatcaaa agatatgcga acataatcac gcttgaacct
      481 gtcactgttc ttccagaaat caggaactat gaatgttcga tagtcgtata ccgcttgacc
      541 tcctgttgtg aacgttcttg aacgtgaatt cctgaagtaa ttccgtgaac tacctgcctg
      601 cacactcgca atccgactag ccagctcctc agctgtttgc gtgagttctg acttgctggc
      661 tttaccattg gccaagttgg tcagttctga cagtctacga gtcgtcgtct cctcatacgt
      721 cgcttgcgct gacttcacgc cagacagttc attcttagtc cgactaagt
//
LOCUS       DAVLUM010000169          747 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.169, whole genome shotgun sequence.
ACCESSION   DAVLUM010000169 DAVLUM010000000
VERSION     DAVLUM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.169"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            301..681
                     /locus_tag="VYN42_002107"
     CDS             301..681
                     /locus_tag="VYN42_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1463097.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
BASE COUNT          235 a          110 c          149 g          253 t
ORIGIN      
        1 gaaactagaa tagtatacct ctacttctaa aacattgtta gaaatcgatt tgactgtcct
       61 gttcttattt cattttacta tatcttaaca gatagtgtaa ataaagataa actatttact
      121 ggctaattga tcagttaaac actagttaag gagtaatgat gaaaaaaaga acaatactat
      181 tattgatggc cagtctgtta gctcttgtct taggagcatg tggtttcttg gacatattga
      241 tcctggatca ttctcatcag gattactctt tactgctatt ttagaaactg gggtggtttg
      301 atggaaagta ttggtattgg tcttgttatc gtttcacatt ccaaacacat tgcagaaggt
      361 gttgttgaac tgattagtaa agtagctaaa gatgttccga ttacttatgt aggaggaacc
      421 gagggcggag gaattggaac gagttttgat caagtagata gggttgtttc cgaaaatcca
      481 gcagatactt tacttgcctt ttttgaccta ggttctgcta aaatgaactt aaaaatggtg
      541 actgatttca gtgataaaag tatcatcatc aacagggttc caattgtaga aggtgcctat
      601 aatgcagctg ctcttcttca ggctggtgca gaactgtcag ttattcaaac acagttagcg
      661 gagcttgaaa tcaataaata aggaatttta ctataactct ttttataggt aagctattga
      721 ttatctcaac tataaaatgt taagtaa
//
LOCUS       DAVLUM010000170          732 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.170, whole genome shotgun sequence.
ACCESSION   DAVLUM010000170 DAVLUM010000000
VERSION     DAVLUM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.170"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(481..>732)
                     /locus_tag="VYN42_002108"
     CDS             complement(481..>732)
                     /locus_tag="VYN42_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1463098.1"
                     /translation="IFLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFL
                     GYLLVIQKAGYLFSVLLLFSNFSVPFIKAKEYELFKNSK"
BASE COUNT          271 a          127 c           91 g          243 t
ORIGIN      
        1 atgtgacgat tctccattta ctccattaaa tcagttttat tttagactat cataaaacaa
       61 tcacctcttc aataaaaacc atttgcgaaa tactattctg aagcattgat agctcagatt
      121 tctcagaata gagctgtcct aactatcgag cagctcaaat acatatatat gagcaattct
      181 aagcctagaa ttgctataaa ataaatgttt ccaggctatt ctaagtcttt gactgcttaa
      241 aattttacat tctgaaggat tctaaagcta gaacagctca aaatcacgag aactaaggta
      301 ttcgaaactt cagagtaata caatccccat aggaattctc cattcttatt aagcatgatt
      361 aaaatgtaat cctaacaagt gatcctcgac tgtgtttgta gcacttagtt acctagataa
      421 gactatttcc ctttattata tctgatttta agccgttcta agatttaacc tatgtttcta
      481 ttacttgcta tttttaaata attcgtattc ctttgctttg ataaatggaa ctgaaaaatt
      541 agaaaaaaga agtaaaaccg aaaacaaata gcctgctttt tgaatcacta aaagatatcc
      601 taaaaataag taagctataa catccaatgc gaaaagaaaa aatattctcc tcttcattaa
      661 agtacttgtg tcaaataatc tgatgaataa aaattttatc gtagtatcta cacaaatttt
      721 tatcaaaaag at
//
LOCUS       DAVLUM010000171          680 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.171, whole genome shotgun sequence.
ACCESSION   DAVLUM010000171 DAVLUM010000000
VERSION     DAVLUM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.171"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..593
                     /locus_tag="VYN42_002109"
     CDS             <1..593
                     /locus_tag="VYN42_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1463099.1"
                     /translation="QIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSNGRGKSTLLRC
                     LIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNELRLGVKNFDEE
                     KAKIILKDLGLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFIFFDEPSSGMDYSNMI
                     KISELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          272 a           77 c          119 g          212 t
ORIGIN      
        1 atcagataaa aaatcttagc tacaaattta ctgatgatga gtgtttaagc ttaaaagata
       61 tttcattcaa gcttgggaaa atttatggca taataggatc caacggacga ggaaaatcaa
      121 cgcttttaag atgtttaata ggtcttgaga aaaaatcaaa agaagaaatt tattttaagg
      181 gagagaagct atctaaaaaa gaaagactca aaaactcttc acttgttatg caagatgtaa
      241 atcatcaatt attcacagat gaagtattca acgagcttag attaggagta aagaattttg
      301 atgaagaaaa ggcgaaaatc attttaaaag atttaggcct ggacgaattt attgaaaggc
      361 atccgatgag tttatcagga gggcaaaagc aaaggcttgc aatagcatct gttatgtgca
      421 agaattctcc atttatcttt tttgacgaac cttcaagtgg tatggattat tccaatatga
      481 taaaaatatc tgaactgatt aataagtata aaaccatgga taaaataatt tttattgttt
      541 cccatgatat agaattttta aatgaagtgg cagatgaaat ttttgaattg taaaatagag
      601 tctgttaaac atgtctatag aactagtaaa ttgtctaaaa atttaaaaga tactaacaca
      661 tattgatatt tatagaaaat
//
LOCUS       DAVLUM010000172          673 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.172, whole genome shotgun sequence.
ACCESSION   DAVLUM010000172 DAVLUM010000000
VERSION     DAVLUM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.172"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..>673
                     /locus_tag="VYN42_002110"
     CDS             <1..>673
                     /locus_tag="VYN42_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="catalyzes the formation of UDP-glucuronate from
                     UDP-glucose; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV1463100.1"
                     /translation="PTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSN
                     KLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTA
                     NIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPRI
                     GNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKP
                     KIVGIY"
BASE COUNT          246 a           85 c          122 g          220 t
ORIGIN      
        1 ccgacagatt atgatgagaa aattggtagt tttaatacat atgaaatcga acaaacggta
       61 tcgaagattc tgagggtaaa acctaatgga aagattattt taaagtcaac agttccgatc
      121 ggcttttcaa acaaattaaa aaggctgttt gatacaaaaa atatcatttt tgtccctgaa
      181 tttttgagag aaggttgttc tatatatgat aatttatatc caagtcgcat agttgttgga
      241 gatgagacag ttgaaggaag aaaaattgca gagttgttcc tttcgattag tactcatagt
      301 actgccaata ttaaaaatgt tatgttagtt tctcctactg aagcagaagc aattaagctt
      361 ttttctaaca cattcttagc tctccgtgtt gcttttttta atgaactaga ttcttttgct
      421 gagaggagaa gtttaaatgc tgaagttgta ataaaaggtg tttgtttaga tccaagaatt
      481 ggaaattttt ataataatcc ttcttttgga tttggaggat attgtcttcc caaagatact
      541 aaacaattaa aaaaagaatt tatagaaata aatgccccag tgatagaagc gattgatatt
      601 tcaaacacaa atagaaaaca gttcatagtt aaacaaatat tggaacgaaa gccaaagata
      661 gtaggaatat ata
//
LOCUS       DAVLUM010000173          634 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.173, whole genome shotgun sequence.
ACCESSION   DAVLUM010000173 DAVLUM010000000
VERSION     DAVLUM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.173"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            69..634
                     /locus_tag="VYN42_002111"
                     /pseudo
     CDS             69..634
                     /locus_tag="VYN42_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835973.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
BASE COUNT          226 a           75 c          107 g          226 t
ORIGIN      
        1 ataaaaagaa aatcattatc agaaaattat gggaggtagt caaactgact tactcaatta
       61 gtgttgtttt gttacatcaa ggagataaaa atagtttatt agagtctttg tcaatagtgg
      121 agagacaaac attaaaagat atagaagtta ttattgtaaa tcaatctaca gaggagatag
      181 cttccattag ccaacagatg aatctatcat ttaatattaa gattatagat gagaattctt
      241 ttgctgagtt gtctgatatg attacaggag attatattac gtttctatct tcaaatgatt
      301 cattatttga ttggacattt gaaaagatgt atcatgcgat aaaattatcc gattctgatg
      361 ttgttcttgg tcattttgct gatttggttg atggagtatt ttacttttat cctttggggg
      421 ggataattgg ttgacagaaa atttaacgaa tgttcaagtt ttacaaaaga tggatgatac
      481 agatcatcga attagaaaac aatatcgctc attatttgga aaattattca atagtaagct
      541 tttacgaaaa ataaatcaat ttgatataaa caaccttatt tggagacttt atattcactc
      601 taaaactgca acctatatta atttcccgac atat
//
LOCUS       DAVLUM010000174          632 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.174, whole genome shotgun sequence.
ACCESSION   DAVLUM010000174 DAVLUM010000000
VERSION     DAVLUM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.174"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            78..374
                     /locus_tag="VYN42_002112"
     CDS             78..374
                     /locus_tag="VYN42_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV1463101.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
BASE COUNT          214 a           80 c          109 g          229 t
ORIGIN      
        1 gaagagagtt aggaatacaa catgtgcgaa ttaactctca ataaaacata cataatatac
       61 aaaaggagta cactaaaatg aaatctaaaa gaatggaatt tcataataaa tttcttattg
      121 tttcagcaat gttagcagtc attagttggt taagcttagg tgttgtttct tttcctatgt
      181 tggctgggac attaggaatt tcgacaaaag ctgctgctac tgtagtcaat ttgattagtg
      241 cttatagtac agttacagca gtaatttcaa ttgtaggtgc aatcacagga gtaggttcta
      301 ttggttcggg tattgcagca acagttcttt atatattgaa aaagaaaggt gctgctaaag
      361 cagctctatg gtagaactag atgaaaatac tttctaaaaa agaatgtgaa agtattttag
      421 gttatcttaa ttttattggg ataacccttt tgttttttgt tatcataagt ttgtcaatct
      481 attttaaaag ctatcttcct tttcaaggga aattattttt actttttttg gtagtagatt
      541 acgctacttt gaatcgttat aatatgaaac tgcctatcca aagtaaaaaa ataaatactt
      601 tctatataag gaaaaactat atttttctct at
//
LOCUS       DAVLUM010000175          615 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.175, whole genome shotgun sequence.
ACCESSION   DAVLUM010000175 DAVLUM010000000
VERSION     DAVLUM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.175"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(130..>615)
                     /locus_tag="VYN42_002113"
     CDS             complement(130..>615)
                     /locus_tag="VYN42_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1463102.1"
                     /translation="YTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADT
                     NQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQVETEKV
                     EEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKES
                     K"
BASE COUNT          125 a          131 c          110 g          249 t
ORIGIN      
        1 ctagtttcaa tctactatat tttgcacatt ttcatgaaaa aaatgagaac tagaactcac
       61 attctgctct catttttcgt tttcccgttc tcctatcctg tttttaggag ttagaaaatg
      121 ctgctacctt tacttactct cctttaataa agccaatagt ttttcagctt ctgccataat
      181 agtattgttg tcctgggtgc caaatagtaa attatttttt aatcctgtga gagtctcttt
      241 ggcattggac ttgataattg gatcctggat ttttccaagt aaatcttcag cctctctcag
      301 tttttcttca accttttcag tctcgacctg aggttcttct gattcctctg gtgattcttc
      361 ttctggttcc tctgttggtt ttggagactc tggtttctcg ctttgcggtt tctcttctcg
      421 aggggtttct tcctcaggtt tttctgtctg aggtttctcc tcgcttggtt tttccgtttg
      481 attggtatca gcttgaccat ttttgtttct ttgaacatgg tcactagcgt taccaaaacc
      541 attatctgaa tgcggacgtt cgtttggatg ttcgacatag tacttgacag tcgccaaaag
      601 atcctcaaga gtata
//
LOCUS       DAVLUM010000176          615 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.176, whole genome shotgun sequence.
ACCESSION   DAVLUM010000176 DAVLUM010000000
VERSION     DAVLUM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.176"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..>615
                     /locus_tag="VYN42_002114"
     CDS             <1..>615
                     /locus_tag="VYN42_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pblB"
                     /protein_id="HEV1463103.1"
                     /translation="ATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDISK
                     TGIWTTSTYTAAIDSESKYLGYNALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGST
                     TNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQT
                     TNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVE"
BASE COUNT          212 a          108 c          139 g          156 t
ORIGIN      
        1 gcaaccaagg ataaagccag caagtcagaa ctcacgcaga cagctgagga gctagctagt
       61 cggattgcga gtgtgcaggc atccggtcga aatctattct tgaactcact attcaagcag
      121 gatatttcaa aaacaggaat ttggacaacg agtacatata cggctgctat cgatagcgaa
      181 agtaagtatc ttggatataa cgctcttaaa attataggtc tgaatccatc tggccgtgat
      241 ggagggaatc ccaaggttac ttatccagct ctgggtcaat tcgggaaagt aattcccgga
      301 agtacgacta atcaagatgt aaccattagt ttttatgcta aggcaaataa aaatggaata
      361 atgctaagat ctcgattagg gaatatcgga tataaaactg gaaatgtgac attgtcgaca
      421 gaaattaaac gatatgttgt ccatattcca aaaggttgga caaacgaatc caagcagacc
      481 acaaatgaat ggttgttcaa tttcaaccag gaaggaaccg tttggatttg gatgccgaag
      541 tttgaaataa gcgatgtaga tacttcttat tcagaagctc ctgaagatat agaaggtcag
      601 atttcaacag ttgaa
//
LOCUS       DAVLUM010000177          538 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.177, whole genome shotgun sequence.
ACCESSION   DAVLUM010000177 DAVLUM010000000
VERSION     DAVLUM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.177"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            <1..>538
                     /locus_tag="VYN42_002115"
     CDS             <1..>538
                     /locus_tag="VYN42_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1463104.1"
                     /translation="ILSNEDLGATNARNIGIKNSRGKYISFLDDDDEYMPDRILKLMA
                     CFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEV
                     LELINGFEKIDSHQDGVVLLKLLVQGYQIDIVREFLVNYYAHSKENGITGVTQKTINA
                     DEEYYNYCRKYFNLLSFNE"
BASE COUNT          199 a           56 c          109 g          174 t
ORIGIN      
        1 attttaagta atgaagattt aggtgcaact aatgccagaa acataggtat caaaaattct
       61 agaggtaagt atatatcatt tttagacgat gatgatgaat atatgccaga tcgaatttta
      121 aagttgatgg cttgttttaa aaagagtaga atgaagaatt tagctttagt ttatagttat
      181 ggaataataa tttatccaaa tggtacacga gaagaggaga agaccgattt tgttggaaat
      241 cccttgtttg ttcaaatggt tcacaatata gcaggtacgt cattttggtt gtgtaaaaaa
      301 gaggtgctag aattaattaa tggttttgag aaaatagatt cacatcagga cggtgttgtt
      361 ttattaaaac tacttgttca aggataccaa attgatatag tgcgagaatt cttggtgaat
      421 tactacgctc acagtaaaga aaacggtatc actggagtga cacaaaaaac aattaatgca
      481 gatgaagaat attataatta ctgtaggaaa tattttaatt tattgagttt caacgaga
//
LOCUS       DAVLUM010000178          519 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.178, whole genome shotgun sequence.
ACCESSION   DAVLUM010000178 DAVLUM010000000
VERSION     DAVLUM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.178"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            complement(<1..483)
                     /locus_tag="VYN42_002116"
     CDS             complement(<1..483)
                     /locus_tag="VYN42_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1463105.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     K"
BASE COUNT          176 a           96 c           60 g          187 t
ORIGIN      
        1 tttcatggaa attaagcgtt tagcaatcat atcaatactt cttgcatcca ctgttgataa
       61 agtctcatca ataaaaatat aatcccaatt tttagcaaaa attaaggata agcctaattt
      121 gaattttgtt ccagtagatg ctgtcatata gttatctccg attttattat caaaaaaagt
      181 attaatttgt tctttatcct caaatgatag atggatttga aaagaatcac acaacaactg
      241 caaattttct tctatagtaa atggaacaac cccaagctga ttggtatcaa ggtatagtac
      301 atctttggag acacaattct ttaaaccact atcaaaagtc tctagcccag ctaaaagttg
      361 tagaagggtg ctctttcctg aaccattctc tccttcaact ctgtaaattc ccttatcaat
      421 ctctagtgat atatttttca atatacattt atcataactt ttagattcat tttcaatttt
      481 cataatttaa ttccctctat caacgctgct aaaattaat
//
LOCUS       DAVLUM010000179          395 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00031973
            SAMN33607348-rid17952433.denovo.179, whole genome shotgun sequence.
ACCESSION   DAVLUM010000179 DAVLUM010000000
VERSION     DAVLUM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607348
            Sequence Read Archive: SRR23725619
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721496.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721496.1
            Genome Coverage       :: 158x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:47:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,117
            CDSs (total)                      :: 2,080
            Genes (coding)                    :: 1,947
            CDSs (with protein)               :: 1,947
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 54 of 133
            Pseudo Genes (incomplete)         :: 62 of 133
            Pseudo Genes (internal stop)      :: 45 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607348-rid17952433.denovo.179"
                     /strain="AUSMDU00031973"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST9107"
     gene            1..253
                     /gene="tnpB"
                     /locus_tag="VYN42_002117"
                     /pseudo
     CDS             1..253
                     /gene="tnpB"
                     /locus_tag="VYN42_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          115 a           77 c           75 g          128 t
ORIGIN      
        1 agactcatta gcctatgtag ttaaaaccca ctttgaattg gatcctttct ccggtcaagt
       61 ctttctcttt tgtggtggac gtaaagaccg ctttaaagcc ctttactggg atggtcaagg
      121 attttggcta ctatataaac gctttgagaa cggaaaactg acttgaccaa gtacagaaaa
      181 ggatgtcaaa gctctcacac ctgaacaagt agactggctt atgaagggct tttctatcac
      241 tccccaaata tagtggattt aaactagaat agtacacccc tacttctaaa acattgttag
      301 aaatcgattt gactgtcctg atcaatttgt cctgttcttg tttcatttta ctatagaacg
      361 atttgaaggc gtttatgata tttagctgta cgaga
//
